ライフサイエンスコーパス: nitration

1 vity, in contrast to the 1:1.3 ratio for the nitration).

2 els of oxidized RNA and enhanced protein Tyr nitration.

3 ates an unusual anaerobic pathway for phenol nitration.

4 -beta-actin association and protein tyrosine nitration.

5 eptide for RhoA 1) to shield Tyr(34) against nitration.

6 for post-translational modification through nitration.

7 and to determine the specific sites of their nitration.

8 OH are significant in prevention of tyrosine nitration.

9 ndrion via a mechanism that requires protein nitration.

10 of particle-bound PAHs toward heterogeneous nitration.

11 de accompanied by extensive vascular protein nitration.

12 ation and Western blot analysis for tyrosine nitration.

13 eased by 40% due to an inactivating tyrosine nitration.

14 with a novel modification of Syt1, tyrosine nitration.

15 roxynitrite production, and protein tyrosine nitration.

16 ced by increases in 3-nitrotyrosine and PGIS nitration.

17 many ECD fragments contained the site(s) of nitration.

18 from normal to inverse electron demand upon nitration.

19 ed oxido-nitrosative stress and lung protein nitration.

20 with the (*)NO2 present, leading to o-phenol nitration.

21 ion is required to trigger midgut epithelial nitration.

22 a slightly deactivating aryl substituent in nitrations.

23 In this work we characterize Prx2 tyrosine nitration, a post-translational modification on a noncat

24 In lieu of the unsatisfactory nitration, a regioselective acylation with Cl3CCOCl was

25 ultiple active chimeras that showed improved nitration activity, increased coupling efficiency and hi

26 alyzed for protein glycation, oxidation, and nitration adducts by stable isotopic dilution analysis t

27 pression, protein nitrosylation, and protein nitration, alleviating nitrosative stress.

28 group has previously demonstrated that STAT1 nitration also mediates MDSC inhibitory effects on immun

29 erobic-anammox cathode MDC (AnA(mox)MDC) and nitration-anammox cathode MDC (NiA(mox)MDC)) were compar

30 t-mediated protein modification via tyrosine nitration and 4-OH-2-nonenol adduction.

31 ) as critical mediators of midgut epithelial nitration and antiplasmodial immunity that enhance nitri

32 In conclusion, oxidized LDL-mediated PGIS nitration and associated thromboxane receptor stimulatio

33 TAT-fused NipR1 attenuated RhoA nitration and barrier disruption in LPS-challenged human

34 ts blocked Ang II effects on Kv4.3, tyrosine nitration and CaMKIIdelta oxidation and activation.

35 transfer, preventing peroxynitrite-dependent nitration and consequent inactivation of Fe-SODB.

36 Both ceruloplasmin tyrosine nitration and cysteine thiol oxidation may be operant in

37 vity while increasing ceruloplasmin tyrosine nitration and cysteine thiol oxidation.

38 bunit of phosphoinositide 3-kinase (PI3K) by nitration and diverts the PI3K-Akt survival signal to th

39 which preceded histological changes, protein nitration and DNA double-strand-break induction.

40 ogenous sources of peroxynitrite resulted in nitration and inactivation of Fe-SODA but not Fe-SODB, s

41 (2) peroxynitrite-mediated posttranslational nitration and inactivation of glial-related enzymes (glu

42 Here, we show that UVB radiation causes nitration and inactivation of MnSOD leading to mitochond

43 Exposure to UVB results in nitration and inactivation of Polgamma, which is prevent

44 tivity of Polgamma by preventing UVB-induced nitration and inactivation of Polgamma.

45 Furthermore, ADMA enhanced Akt1 nitration and increased its activity.

46 In WT mice, hyperoxia elicited tyrosine nitration and inhibition of sEH and decreased generation

47 The second involves post-translational nitration and modification of glia-derived proteins know

48 eonicotinoid insecticide) to photoinduce the nitration and nitrosation of three aromatic probes (phen

49 The contribution of NO(3)(-)/NO(2)(-) to the nitration and nitrosation processes was found to be mino

50 ond-forming reactions (amination, amidation, nitration and nitrosation) that involve the use of boron

51 There is much interest in the nitration and oxidation reaction mechanisms initiated by

52 ecies) production such as inhibiting protein nitration and protein aldehyde formation and specificall

53 site with substrate protects against Tyr385 nitration and redirects nitration to alternative Tyr res

54 serum FeOxI is associated with ceruloplasmin nitration and reduced survival in patients with HF.

55 cells was resistant to peroxynitrite-induced nitration and reduction of A subunit binding.

56 ls of serum protein glycation, oxidation and nitration and related hydrolysis products, glycation, ox

57 NOS causes marked mitochondrial cytochrome c nitration and release and subsequent photoreceptor apopt

58 ion at S70 directly correlates with B56delta nitration and repression of SOD1, but inversely correlat

59 l cells resulted in marked decrease of IRAK4 nitration and restored the inflammatory response after l

60 ite, NOx, S-nitrosoglutahione reductase, Tyr-nitration and S-nitrosylation along with the expression

61 ms, based on fluorescein bleaching, tyrosine nitration and serum albumin thiol oxidation.

62 The two-stage nitration and subsequent deacetylation of readily availa

63 response to lipopolysaccharide through IRAK4 nitration and the resultant impairment of kinase activit

64 logical mechanisms accounting for fatty acid nitration and the specific structural characteristics of

65 mechanisms that target ookinetes-epithelial nitration and thioester-containing protein 1 (TEP1)-medi

66 itrotyrosine (NY), Akt and p38 activity, p85 nitration, and caspase-3 cleavage were measured in brain

67 d peroxynitrite-induced FeOxI drop, tyrosine nitration, and cysteine oxidation; flavonoid(-)-epicatec

68 n adducts, protein carbonyl content, protein nitration, and DNA damage determined by the content of 8

69 ncreased generation of nitric oxide, protein nitration, and lipid peroxidation.

70 uantification of the extent of chlorination, nitration, and oxidation in human hemoglobin and to exam

71 The extents of chlorination, nitration, and oxidation of a total of 12 sites and type

72 Signaling protein levels, nitration, and phosphorylation were quantitated by immun

73 ased formation of protein carbonyls, protein nitration, and protein S-nitrosylation.

74 l oxidized LDL and glycated LDL levels, PGIS nitration, and retina cell apoptosis, thereby preserving

75 Thus, tyrosine nitration appears as another mechanism to modulate these

76 Peroxynitrite production and tyrosine nitration are present in several pathological conditions

77 igarette smoking and the extents of tyrosine nitration at alpha-Tyr-24 and at alpha-Tyr-42.

78 or of smoking, chlorination at alpha-Tyr-24, nitration at alpha-Tyr-42, and oxidation at the three me

79 the extents of chlorination at alpha-Tyr-24, nitration at alpha-Tyr-42, and oxidation at the three me

80 sequence-specific identification of protein nitration at low concentrations of 3-NT in complex prote

81 rategy enabled us to investigate the role of nitration at single or multiple tyrosine residues in reg

82 not been possible to determine the roles of nitration at specific residues in regulating the physiol

83 This resulted in site-specific nitration at the 70 kDa polypeptide and impairment of co

84 s is a critical residue for COX-1 catalysis, nitration at this site results in enzyme inactivation.

85 , we found that PKG-1alpha is susceptible to nitration at tyrosine 247 and 425.

86 sisting of sulfonylation at cysteine 674 and nitration at tyrosines 294/295.

87 gain a more mechanistic understanding of how nitration attenuates PKG activity, we developed a homolo

88 Previous studies have shown that tyrosine nitration attenuates PKG-1alpha activity.

89 and functional importance of apoA-I Tyr(166) nitration based upon studies of HDL-like particles recov

90 Herein we report the creation of improved nitration biocatalysts through constructing and characte

91 rp uncovered remarkable regio-promiscuity of nitration biocatalysts.

92 loride (L-NIL) solely restricts lung protein nitration but fails to prevent or reverse the major toba

93 chin, which prevented ceruloplasmin tyrosine nitration but not cysteine oxidation, partially impeded

94 first detailed insight into the mechanism of nitration by a member of the TxtE subfamily and highligh

95 The reactivity of ambient particles toward nitration by N2O5/NO3/NO2, defined by relative 1-NPY for

96 However, the examined nitration by NO2(+) is supported by (1) the absence of 3

97 teine 674 sulfonylation and tyrosine 294/295 nitration, (c) restored SERCA activity, and (d) improved

98 The nitration can enhance the allergenic potential of protei

99 The reaction proceeded as a nitration-debromination sequence to highly stereoselecti

100 en ovalbumin (OVA) was nitrated in different nitration degrees, and the secondary structures of prote

101 ransport via RhBG at 3 months and a tyrosine nitration-dependent inactivation of GS in 12-month-old T

102 longation is interrupted upon Y10 nitration: Nitration disrupts fibril-forming folds by preventing H1

103 showed that peroxynitrite-mediated tyrosine nitration down-regulates mitochondrial metabolism in tum

104 oxidized LDL and glycated LDL, induced PGIS nitration, enhanced apoptotic cell death, and impaired b

105 When multiple potential sites of nitration exist, tandem mass spectrometry (MS/MS) method

106 Kinetic analyses suggest that tyrosine nitration facilitates the intermolecular disulfide forma

107 ned urinary protein glycation, oxidation and nitration free adducts by stable isotopic dilution analy

108 ydrolysis products, glycation, oxidation and nitration free adducts in patients with type 1 diabetes

109 Post-translational protein nitration has attracted interest owing to its involvemen

110 We report that nitration (i.e., the irreversible addition of a nitro gr

111 Pathways of GUA nitration in aqueous solution under atmospherically rele

112 nitration in polluted air, while the rate of nitration in bulk material may be low depending on phase

113 increased SK/IK protein levels and tyrosine nitration in cultured human cardiac microvascular endoth

114 of the other four tyrosine residues prone to nitration in Hsp90, was sufficient to down-regulate mito

115 activation at low NO levels, the role of Tyr nitration in p53 activation was evaluated.

116 e reported that oxidative modifications, and nitration in particular, of T cells as well as serum pro

117 ate in protecting COX-1 from inactivation by nitration in pathophysiological settings.

118 e surface of aerosol particles undergo rapid nitration in polluted air, while the rate of nitration i

119 Tyrosine nitration in proteins is an important post-translational

120 possibilities for investigating the role of nitration in regulating protein structure and function i

121 ciation, eNOS activity, and protein tyrosine nitration in the lungs.

122 lity of "shielding" peptides to prevent RhoA nitration in the management of ALI.

123 discovered low endogenous levels of tyrosine nitration in the peptide YYCFQGNQFLR in the heme-binding

124 tudies show that phenolic substrates undergo nitration in the presence of PN or PN-metal complexes, i

125 Tyrosine nitration in these conditions has been reported extensiv

126 study we evaluated the possible role of RhoA nitration in this process.

127 primary endogenous substrate for fatty acid nitration in vitro and in vivo, yielding up to 10(5) gre

128 pid peroxidation, protein carbonylation, and nitration in WAT and liver.

129 ation, methylthiolation, S-nitrosylation and nitration) in a natural microbial community from an acid

130 tyrosine formation (ONOO(-)-specific protein nitration) in endothelial plasma membrane in DM, which c

131 rtook this study to test our hypothesis that nitration inactivates PKCdelta, contributing to impaired

132 eroxynitrite promoted further PDI oxidation, nitration, inactivation, and covalent oligomerization.

133 atic and cellular mechanisms account for CLA nitration, including reactions catalyzed by mitochondria

134 ells have high levels of endogenous tyrosine nitration, indicating production of peroxynitrite.

135 f alpha-syn play critical roles in mediating nitration-induced alpha-syn oligomerization.

136 phenyl)porphyrinato iron III chloride or the nitration inhibitor epicatechin.

137 re, we developed a peptide designated NipR1 (nitration inhibitory peptide for RhoA 1) to shield Tyr(3

138 Protein nitration is a frequent post-translational modification

139 n reported extensively, but whether tyrosine nitration is a marker or plays a role in the cell-death

140 Tyrosine nitration is an important sequel of cellular signaling i

141 tal chelators, and heme ligands reveals that nitration is contingent upon the binding of nitrite to h

142 Biological protein nitration is involved in several disease states, includi

143 Protein nitration is involved in the endothelial barrier dysfunc

144 Increased protein glycation, oxidation and nitration is linked to the development of diabetic nephr

145 In the nucleus of NOS activated cells, nitration levels of beta-catenin influenced its associat

146 In addition, tyrosine nitration may help regulate the repair cycle of photosys

147 ase inactivation, NO consumption, or protein nitration may modulate the biological actions of IDO exp

148 ring posttranslational modifications such as nitration may play a role in antibody-mediated autoimmun

149 ns, but precise localization of the sites of nitration may require either of the "slow-heating" metho

150 First, we confirm the recently proposed nitration mechanism, advancing the understanding of atmo

151 dues to alanine (S617A and S1179A) inhibited nitration-mediated eNOS translocation to the mitochondri

152 Thus, we have identified a new mechanism of nitration-mediated RhoA activation involved in LPS-media

153 Enantioselective electrophilic aromatic nitration methodology is needed to advance chirality-ass

154 athology involving oxidative damage, protein nitration, myofiber cell death and marked neuromuscular

155 ch fibril elongation is interrupted upon Y10 nitration: Nitration disrupts fibril-forming folds by pr

156 g phosphorylation, acetylation, methylation, nitration, nitrosylation, and sulfoxidation and consider

157 Whether PGIS nitration occurs in human diabetic atherosclerotic arter

158 d to produce nitronium ion, leading to ortho-nitration of 2,4-di-tert-butylphenol (DTBP).

159 zo-1,2,4-oxadiazole (4), was obtained by the nitration of 5,5'-diamino-3,3'-azo-1,2,4-oxadiazole usin

160 Among numerous approaches, nitration of a 3-farnesyl-substituted unprotected pyrrol

161 Nitration of a 76-kDa cochlear protein correlated with c

162 O can promote the regio- and stereoselective nitration of a broad range of olefins.

163 of PP2A results from peroxynitrite-mediated nitration of a conserved tyrosine residue within B56delt

164 and efficient method for the regioselective nitration of a series of aliphatic and aromatic carboxyl

165 s reveal that cell death can be triggered by nitration of a single protein and highlight nitrated Hsp

166 Here, we show that nitration of a single tyrosine residue on a small propor

167 seful reagent for regio- and stereoselective nitration of a wide variety of aromatic, aliphatic, and

168 We assessed S-nitrosylation and nitration of AJ-associated proteins to identify downstre

169 e AgNO2/Pd(PPh3)4-promoted regiocontrolled o-nitration of alpha-sulfonylmethylstyrenes in MeNO2 with

170 The resultant nitration of amino acids is considered a specific effect

171 tion of a diazonium compound was observed by nitration of an amino substituted triazolyl tetrazole wi

172 Thus, site-specific nitration of apoA-I at Tyr(166) is an abundant modificat

173 The nitration of aromatic amines by the photofragmentation p

174 PCET) mediated regioselective ortho-specific nitration of aromatic C(sp(2))-H bonds using chelation-a

175 gent was prepared and used for the efficient nitration of aromatic compounds (even aniline derivative

176 The nitration of benzene by nitronium ion in the gas phase h

177 Moreover, high NO levels provoked nitration of beta-catenin, and induced its translocation

178 Iron(III)-mediated radical nitration of bisarylsulfonyl hydrazones is described.

179 The ipso-nitration of calix[6]arene-based molecular receptors is

180 The atmospherically relevant nitration of catechols is taken as a case example.

181 Together these data suggest that nitration of CCL2 during inflammation provides a mechani

182 Cisplatin induced nitration of cellular proteins within the organ of Corti

183 ant Oxr1 attenuated oxidative stress marker, nitration of cellular proteins, and ameliorated apoptosi

184 his inhibition was mediated through tyrosine nitration of chlamydial protein by peroxynitrite, an NO

185 Nitration of CyPD and ANT in LGN mitochondria occurs by

186 ) emission signal at 550 nm is observed upon nitration of DHAs due to the generation of fluorescent d

187 thesized easily in a one-step process by the nitration of FOX-7 in high yield (>93%).

188 PO is the major pathway for chlorination and nitration of HDL in human atherosclerotic tissue.

189 on monitoring were used to quantify tyrosine nitration of in vivo samples and when hemopexin was incu

190 s insulin action in hepatocytes via tyrosine nitration of insulin receptors.

191 Furthermore, in vitro nitration of IRAK4 resulted in impairment of the kinase

192 In vitro nitration of Lba with excess nitrite produced several is

193 h, these results support the hypothesis that nitration of Lmo4 influences cisplatin-induced ototoxici

194 cochlear proteins and is the first to report nitration of Lmo4.

195 monary Rtp801 and consequent iNOS/NO-induced nitration of lung proteins, that otherwise lead to incre

196 Cu-catalyzed chemo- and regioselective ortho-nitration of N,1-diaryl-5-aminotetrazoles and N,4-diaryl

197 Cu-catalyzed chemo- and regioselective ortho-nitration of N,1-diaryl-5-aminotetrazoles and N,4-diaryl

198 Regioselective ring nitration of N-alkyl anilines is reported using tert-but

199 reactions, an alternative route through the nitration of N-ethoxycarbonyl-protected 3,4-diaminofuraz

200 Molecular modeling indicates that nitration of one Tyr327 stabilizes the dimer by about 2.

201 eased endothelial permeability, also induced nitration of p120-catenin-associated p190RhoGAP-A.

202 Thus, eNOS-dependent nitration of p190RhoGAP-A represents a crucial mechanism

203 xygenation injury dramatically increased the nitration of p85 and activation of p38 but decreased Akt

204 ) are formed in combustion activities and by nitration of PAHs in the atmosphere and may be equally o

205 apoptosis, accompanied by increased tyrosine nitration of PGIS and decreased PGIS activity.

206 etes, suggesting a possible role of tyrosine nitration of PGIS in the development of atherosclerosis

207 We propose that VCP/p97-mediated Tyr nitration of PP2A increases the levels of phosphatases P

208 sent study was to determine whether tyrosine nitration of prostacyclin synthase (PGIS) contributes to

209 ling by interaction with diverse targets and nitration of protein tyrosines.

210 NO and its derivatives induce nitration of proteins during inflammation.

211 Nitration of Prx has been reported in vitro as well as i

212 Radical nitration of readily available 2-bromo-2-fluorostyrenes

213 Our data demonstrate that both nitration of specific tyrosine residues and interaction

214 showed that the inactivation was related to nitration of specific tyrosine residues in the three sub

215 Nano-LC-MS/MS showed this was related to de-nitration of specific tyrosine residues, suggesting KGDH

216 T. cruzi Fe-SODs is due to the site-specific nitration of the critical and universally conserved Tyr(

217 h undergoes I2 -catalyzed oxidative alpha-CH nitration of the nitromethyl subunit followed by [3+2] c

218 Nitration of the pro-survival chaperone heat shock prote

219 We find that nitration of the single tyrosine (Y39) in this domain di

220 em mass spectrometry assay demonstrated that nitration of the STAT1-Tyr701 occurs in PBMC derived fro

221 Moreover, we observe that nitration of the three tyrosines (Y125/133/136) in the C

222 , and a general trend for the regioselective nitration of three aromatic units out of six in moderate

223 The regiochemistry of the nitration of toluene by NO2(+)BF4(-) in dichloromethane

224 supports H(2)O(2)/ONOO(-)-mediated oxidation/nitration of TPH1 and DDC, affecting, in turn, enzyme fu

225 Nitration of Tyr often causes loss of protein activity a

226 Our study shows that the nitration of Tyr(247) and the attenuation of cGMP bindin

227 ited preserved activity, suggesting that the nitration of Tyr(247) is critical in attenuating PKG-1al

228 This model predicted that the nitration of Tyr(247) would decrease the affinity of PKG

229 NO derived from iNOS mediates nitration of tyrosine residues in IRF5 protein, leading

230 NO mediates nitration of tyrosine residues in RORgammat, leading to

231 on by investigating the effects of oxidative nitration of tyrosine residues on the structure of aS an

232 genes, ArgR, showed that post-translational nitration of tyrosine residues within this protein is re

233 peroxynitrite caused a fairly indiscriminate nitration of tyrosine residues, reversible modifications

234 Nitration of tyrosine reverses the tyrosine inhibition o

235 The oxidation and nitration of unsaturated fatty acids by oxides of nitrog

236 Nitration of Y(56) and Y(142) was previously reported.

237 These results lead us to suggest that nitration of Y125/133/136 reduces the membrane-binding a

238 dynamics simulations predicted that tyrosine nitrations of CYP2B6 would cause significant destabilizi

239 We propose that cumulative nitrations of Y190, Y317, and Y380 by reactive nitrogen

240 mice was associated with increased levels of nitration on STAT1.

241 Nitration on Tyr-24, Tyr-42 (alpha-globin), and Tyr-130

242 y established that COX-1 undergoes selective nitration on Tyr385 via a mechanism that requires the pr

243 er, post-translational modifications such as nitration, phosphorylation, and sulfoxidation of specifi

244 xpands our ability to study the role protein nitration plays in disease development through producing

245 evidence of residual but significant protein nitration, prevalent oxidative DNA damage, and poly(ADP-

246 Inhibition of cochlear protein nitration prevented cisplatin-induced hearing loss.

247 urthermore, a newly developed regioselective nitration procedure for perylene monoimide diesters (PMI

248 me binding by hemopexin declined as tyrosine nitration proceeded in vitro Three nitrated tyrosines re

249 The o-nitration process provides a series of sulfonyl o-nitros

250 Finally, a biocatalytic nitration process was developed to nitrate 4-Me-DL-Trp.

251 ly described the development of biocatalytic nitration processes driven by an engineered P450 TxtE fu

252 h are also involved in physiological protein nitration processes.

253 , with the maximal yield of the oxidation or nitration product occurring at a 1:1 ratio.

254 Notably, covalent nitration products 4, 5 and 6, 7 were obtained by reacti

255 vivo, yielding up to 10(5) greater extent of nitration products as compared with bis-allylic linoleic

256 isomers purified from the biomimetic acidic nitration products of conjugated linoleic acid (CLA).

257 ing rate constants of nitration with NO2(+), nitration rates are competitive under nighttime and liqu

258 A direct and selective aromatic nitration reaction may be useful in biotechnology for th

259 increase in the relative rate of an aromatic nitration reaction, affording functionalization on the a

260 gy controls the stereochemistry of threefold nitration reactions from above the aromatic rings with c

261 on and triggers cell death via oxidation and nitration reactions.

262 133F, Y136F and Y133/136F) can still undergo nitration readily to form higher-order oligomers.

263 e plasmon resonance spectroscopy showed that nitration reduced heparan sulphate binding by CCL2.

264 Nitration reduced the potential of CCL2 to stimulate mon

265 odulin nitrated at Tyr-99 revealed that this nitration reduces nitric-oxide production and increases

266 SK/IK activities via oxidation- and tyrosine nitration-related mechanisms.

267 everal caspases, resulting in an ineffective nitration response that makes the parasite undetectable

268 Pfs47 suppresses midgut nitration responses that are critical to activate the co

269 Furthermore, inhibition of B56delta(Y289) nitration restores PP2A holoenzyme assembly, thereby per

270 Our investigations show that tyrosine nitration results in a change of the conformational stat

271 Mass spectrometry identified a single nitration site in Akt1 located at the tyrosine residue (

272 We also found that Tyr-192 is the major nitration site in apoA-I of circulating HDL but that Tyr

273 sion HDL, and Tyr-18 of apoA-I was the major nitration site in HDL exposed to MPO in vitro, suggestin

274 Mass spectroscopy identified a single nitration site, located at Tyr(34) in RhoA.

275 CuCl2.2H2O as catalyst and Fe(NO3)3.9H2O as nitration source at room temperature.

276 CuCl2.2H2O as catalyst and Fe(NO3)3.9H2O as nitration source at room temperature.

277 tomic force microscopy, we report that Abeta nitration stabilizes soluble, highly toxic oligomers and

278 t depending on the cell type, distinct Hsp90 nitration states regulate different aspects of cellular

279 uggested that the mechanism by which Tyr(34) nitration stimulates RhoA activity was through a decreas

280 This nitration strategy controls the stereochemistry of three

281 eported here is an enantioselective aromatic nitration strategy operating with chiral diester auxilia

282 as halogenation, formylation, carboxylation, nitration, sulfonation, and others are discussed in deta

283 5F-PKG-1alpha, were both less susceptible to nitration than WT PKG-1alpha, but only Y247F-PKG-1alpha

284 that diabetes preferentially increases PGIS nitration that is associated with excessive vascular inf

285 was performed to determine the potential for nitration to alter the chemical and biological propertie

286 tects against Tyr385 nitration and redirects nitration to alternative Tyr residues on COX-1, preservi

287 ne is required for mitigating damaging lipid nitration under nitrooxidative stress conditions and, co

288 ctive iminoquinone intermediate (2OHCBZ) and nitration via peroxynitrite (2OHCBZ and 3OHCBZ) as well

289 roxidase substrates, NO consumption, and IDO nitration was inhibited by l-Trp.

290 tive nitrogen species and prevents DNA bases nitration, what makes beech seeds oil interesting raw ma

291 d, for example, by posttranslational protein nitration, which also occurs via diet-derived nitrating

292 Oxidative stress causes PKCdelta nitration, which prevents its phosphorylation and contri

293 ster than that of NO and also leads to l-Trp nitration, while little evidence of product formation is

294 iate in the classic SEAr reaction of benzene nitration with mixed acid.

295 rder kinetic rate constants of methoxyphenol nitration with NO2(*) are substantially higher than the

296 her than the corresponding rate constants of nitration with NO2(+), nitration rates are competitive u

297 ed myocardial complex II to in vitro protein nitration with OONO(-).

298 sttranslational modification of proteins via nitration within atherosclerotic plaque-laden arteries a

299 sequentially, and we propose that epithelial nitration works as an opsonization-like system that prom

300 For example, when Y39 is not available for nitration (Y39F and Y39/125F), the extent of cross-linki