ライフサイエンスコーパス: non-canonical

1 be pathogenic within the thalamic network is non-canonical.

2 5' end N(7)-methyl guanosine (m(7)G) cap, a non-canonical 5' nicotinamide adenine dinucleotide (NAD(

3 ple helix can tolerate up to two consecutive non-canonical A*G-C base triplets.

4 asion of epithelial breast cancer cells, via non-canonical activation of GLI-signaling.

5 de of LTbetaR signalling dampened epithelial non-canonical activation of NF-kappaB, reduced TGFbeta s

6 ng human beige adipose tissue and identified non-canonical activators.

7 Recent studies have revealed non-canonical activities of apoptotic caspases involving

8 Our study reveals a non-canonical adaptive mechanism by which thermal stress

9 ernally-functionalized DNA nanowires through non-canonical, Ag(+)-mediated base pairing in duplexes c

10 nformational properties of disease-relevant, non-canonical aggregates.

11 roteasome assembly in mutant yeast producing non-canonical alpha4-alpha4 CPs.

12 y, heterologous celC expression also induced non-canonical alterations in ROS (Reactive Oxygen Specie

13 Here, we rationally design non-canonical amino acid analogs with extended carbon ch

14 global degradation rates in tissues using a non-canonical amino acid and mass spectrometry.

15 lar dynamics simulations and state-dependent non-canonical amino acid cross-linking.

16 ts the cellular incorporation of one type of non-canonical amino acid into a protein - to enable the

17 tive place avoidance task and bio-orthogonal non-canonical amino acid tagging (BONCAT) followed by SW

18 Here, we apply bioorthogonal non-canonical amino acid tagging (BONCAT) to visualize a

19 Here, we use BONCAT (bioorthogonal non-canonical amino acid tagging) to measure translation

20 n initiate translation in vivo with aromatic non-canonical amino acids (ncAAs) bearing diverse sidech

21 labelling of newly synthesised proteins with non-canonical amino acids (NCAAs) by genetically restric

22 ode expansion (GCE) technologies incorporate non-canonical amino acids (ncAAs) into proteins at amber

23 Herein, we report a system for incorporating non-canonical amino acids (ncAAs) into proteins displaye

24 s for the incorporation of multiple distinct non-canonical amino acids (ncAAs), and the encoded biosy

25 d direct the incorporation of three distinct non-canonical amino acids into a single polypeptide.

26 proteins, and can also incorporate multiple non-canonical amino acids into synthesized polypeptides.

27 he encoded incorporation of several distinct non-canonical amino acids.

28 ence suggests that phosphorylation of other "non-canonical" amino acids also regulates critical aspec

29 -specific incorporation of the azide-bearing non-canonical-amino-acid azidonorleucine (ANL) during pr

30 Non-canonical and C-to-U RNA-editing events are enriched

31 dothelial cells (HDMECs), we found that both non-canonical and canonical p38 activation pathways comp

32 In summary, our results identify ALK5 and non-canonical androgen receptors as potential therapeuti

33 Despite their non-canonical architecture and mechanochemistry, Schizos

34 hat activates G protein-dependent as well as non-canonical arrestin-dependent signaling pathways.

35 and clonogenicity of hepatocytes by a novel non-canonical/atypical beta-catenin-dependent mechanism.

36 IAA33 is a non-canonical AUX/IAA protein lacking a TIR1-binding dom

37 ides insight into the molecular functions of non-canonical AUX/IAA proteins in auxin signaling transd

38 This non-canonical axis of the renin-angiotensin system consi

39 ), a class of non-coding RNAs generated from non-canonical back-splicing events, have emerged to play

40 nstrate site-specific incorporation of these non-canonical, backbone-extended monomers at the N- and

41 tagonistic relationship between LSD1 and the non-canonical BAF (ncBAF) chromatin remodelling complex.

42 n as GLTSCR1, which encodes a subunit of the non-canonical BAF (ncBAF) complex.

43 Depletion of BRD9 causes the loss of non-canonical BAF at CTCF-associated loci and promotes m

44 s a core component of the recently described non-canonical BAF chromatin-remodelling complex that als

45 Our results implicate the disruption of non-canonical BAF in the diverse cancer types that carry

46 e triplets were the most stable, while three non-canonical base triplets completely disrupted triple-

47 hyl-5-uridine (m5U) is one the most abundant non-canonical bases present in cellular RNA, and in yeas

48 understanding of chemical modifications and non-canonical bases; this in turn requires advances in c

49 However, the basis for the non-canonical biogenesis of miR-451 is unclear.

50 enable the genetically encoded synthesis of non-canonical biopolymers and provide a platform for tra

51 ids (ncAAs), and the encoded biosynthesis of non-canonical biopolymers, requires the discovery of mul

52 expected set of free circular introns with a non-canonical branchpoint enriched in neuronal projectio

53 an also remove FAD and dephospho-CoA (dpCoA) non-canonical caps from RNA, and we have named these act

54 nging to the genus Leishmania synthesize the non-canonical carbohydrate reserve, mannogen, which is c

55 zyme that uses N(delta)-methylhistidine as a non-canonical catalytic nucleophile.

56 Bacteria with these non-canonical cell-wall cross-links achieve a high optic

57 d surface area in the front sheet due to the non-canonical conformation of the CC' loop, which provid

58 function uniquely in sensory neurons through non-canonical coupling to ion channels, enabling rapid m

59 The mechanisms that control canonical versus non-canonical CP biogenesis remain poorly understood.

60 ith seven subunits arranged alpha1-alpha7, a non-canonical CP in which a second copy of the alpha4 su

61 Here we report a non-canonical cross-coupling approach for the constructi

62 re the biological consequence of introducing non-canonical cross-links into the cell wall of Escheric

63 how that rodent mitoCLU is translated from a non-canonical CUG (Leu) start site in Exon 3, a site tha

64 Notably, we identified a non-canonical cytochrome P450 that catalyses the remarka

65 chemical and in vivo analysis, we identify a non-canonical D box (D2) that is critical for cyclin A2

66 evidence suggests that cocaine also triggers non-canonical, DA-independent, mechanisms that contribut

67 malaria parasite Plasmodium falciparum, and non-canonical databases, which we show by detecting miss

68 es have demonstrated that they also activate non-canonical DDRs (ncDDRs) that regulate cell type-spec

69 nscriptional activator and repressor, with a non-canonical deacetylase-independent function that is v

70 GSCs have a non-canonical distribution of PRC2 activity and lack sil

71 Here we reveal a non-canonical DNA damage response, which we call RING (r

72 nal change that mediates stable binding to a non-canonical DNA motif.

73 We identify a non-canonical E-box element in Bmal1 and demonstrate tha

74 it was reported that AspH substrates have a non-canonical EGFD disulfide pattern.

75 uding internal tandem duplications and other non-canonical events in 170 pediatric cancer transcripto

76 Crystal structures reveal that PaClpP2 has non-canonical features in its N- and C-terminal regions

77 els in a native, membrane environment with a non-canonical fluorescent amino acid and measurement (us

78 yield an abasic site driving formation of a non-canonical fold, such as a G4, to be displayed to apu

79 dification in DNA, in which DNA "damage" and non-canonical folds collaborate to turn on or off gene e

80 Reiterative transcription is a non-canonical form of RNA synthesis by RNA polymerase in

81 tive abundance of 133 isomiRs, including the non-canonical forms of the aforementioned miRNAs.

82 cytoplasmic domain of IncA, which reveals a non-canonical four-helix bundle.

83 Guanine-quadruplexes (G4s) are non-canonical four-stranded structures that can be forme

84 We have identified a novel non-canonical function of several autophagy proteins in

85 This study focuses on the non-canonical function of the Wnt16 ligand during early

86 Our data reveal a non-canonical function of YAP1 and TEAD4 as ERalpha cofa

87 Finally, we discuss the non-canonical functions of cutaneous immune cells includ

88 However, the non-canonical functions of DGCR8 have not been studied.

89 rse cellular regulatory mechanisms including non-canonical functions outside the chromatin environmen

90 enetic code during protein synthesis, and in non-canonical functions unrelated to translation.

91 dentify varying neutrophil states and assign non-canonical functions, including vascular repair and h

92 complex trafficking open the possibility for non-canonical functions.

93 can be switched from protein biosynthesis to non-canonical functions.

94 We have previously shown that non-canonical Fzl1/2/7 signaling antagonizes the progres

95 ties for selective chemical targeting of the non-canonical G-quadruplex structure within the PARP1 pr

96 genome-mapping experiments have identified a non-canonical G-quadruplex-forming sequence containing b

97 that Galphaq activates FAK through TRIO-RhoA non-canonical Galphaq-signaling, and genetic ablation or

98 GQ stabilizing compound, berberine, to these non-canonical genetic structures using UV-Vis and fluore

99 ng experiments using various combinations of non-canonical gRNAs and different Cas9s.

100 Non-canonical gRNAs and new engineered variants of Cas9

101 all transmembrane helices have at least one non-canonical H-bond formed by a serine or threonine res

102 ere, we report that RNF168 ubiquitinates the non-canonical H2A variants H2AZ and macroH2A1/2 at the d

103 and NOR logical controls in addition to two non-canonical half-AND operations.

104 nonical strain Merlin HCMV proteins, and two non-canonical HCMV proteins, in infected cells.

105 y and was applied to predict the presence of non-canonical HD-GYP phosphodiesterases in many bacteria

106 an importance of hypoxia-independent, i.e., non-canonical, HIF-1 stabilization for intestinal tumori

107 ctin interaction toward nucleosomes with the non-canonical histone H2A.Z, thereby focusing the pathwa

108 ion of hundreds of shared and tumor-specific non-canonical HLA peptides, including an immunogenic pep

109 (AT)12 forms stable periodic structures with non-canonical hydrogen bonds in some regions and non-can

110 hage priming by inhibiting the activation of non-canonical IkappaB kinase varepsilon and IkappaBalpha

111 Small-molecule inhibitors of non-canonical IkappaB kinases TANK-binding kinase 1 (TBK

112 ls distinct epigenetic mechanisms regulating non-canonical imprinted gene expression between embryoni

113 ed clusters and eight other genes, including non-canonical imprinted genes.

114 ver, the underlying regulatory mechanisms of non-canonical imprinting in post-implantation developmen

115 This novel maternal H3K27me3-mediated non-canonical imprinting mechanism further emphasizes th

116 ation-dependent (canonical) and independent (non-canonical) imprinting by assaying hybrid embryos wit

117 We find that non-canonical imprints are localized to endogenous retro

118 that oocyte-derived H3K27me3 associated with non-canonical imprints is not maintained beyond pre-impl

119 Additionally, LysRS acts as a non-canonical inducer of the immune response and has tra

120 h significant increase in both canonical and non-canonical inflammasome activation and decrease in T-

121 an unexpected role for cathepsin activity in non-canonical inflammasome regulation.

122 On the other hand, caspase-11 delineates a non-canonical inflammasome that promotes pyroptotic cell

123 s required for pyroptotic cell death via the non-canonical inflammasome, and that lipopolysaccharide

124 an E. coli strain in which the efficiency of non-canonical initiation equals elongation.

125 The non-canonical initiation factor DENR promotes translatio

126 ing long non-coding (lnc) RNA that activates non-canonical innate immune signaling upon detection of

127 A new study demonstrates how a non-canonical interaction of ECT2 with centralspindlin u

128 in the Golgi endomembranes and suggest that non-canonical interactions between MET and other RTKs oc

129 d in vitro motility assays, we elucidate the non-canonical interactions that drive this motor's funct

130 of PV+INTs and results in the emergence of a non-canonical 'intermediate spiking (IS)' subset of PV+I

131 lows a developmental program that alternates non-canonical intraerythrocytic replication with dissemi

132 They show that GluD1, through a non-canonical ionotropic-independent mechanism, controls

133 ponent of the meiotic cohesin complex, via a non-canonical JAK/STAT pathway, and consequently promote

134 We confirm associations at 13 non-canonical loci, with two involving non-coding region

135 do not fully understand how networks of such non-canonical macromolecules generate behavior.

136 clearance of pathogenic SIV challenge virus, non-canonical major histocompatibility complex restricti

137 Here we reveal a non-canonical mechanism by which GPR158 exerts its effec

138 that KRAS-mutated cells acquire copper via a non-canonical mechanism involving macropinocytosis, whic

139 This non-canonical mechanism of MAPK activation couples T3 ac

140 at holo-WhiB1 regulates gene expression by a non-canonical mechanism relative to well-characterized s

141 e expression of inflammatory genes through a non-canonical mechanism.

142 ctionality of the Nudix decapping enzymes on non-canonical metabolite caps.

143 kable groups using azidohomoalanine (AHA), a non-canonical methionine analogue containing an azide gr

144 n originate from dedicated miRNA genes, from non-canonical miRNA genes, or from mirror-miRNA genes an

145 function of uridylated isomiRs in regulating non-canonical miRNA targets.

146 ew unbiased method to identify canonical and non-canonical miRNA-binding sites from peaks identified

147 Mirtrons are non-canonical miRNAs arising by splicing and debranching

148 omes between strains, and the assessments of non-canonical mitosis events.

149 d solution NMR data support the existence of non-canonical modes of HJ interaction in solution.

150 n repair proteins BLM and BRCA2 as well as a non-canonical monoubiquitylation-independent function of

151 (GTAAAC/T) but were enriched for a related, non-canonical motif (GTAAAG/A), which was preferentially

152 '-OH ends inflicted during tRNA splicing and non-canonical mRNA splicing in the fungal unfolded prote

153 mes can eliminate most of the incomplete and non-canonical NAD caps through their decapping, deNADdin

154 otic mRNA 5'-end quality control, removal of non-canonical NAD+ cap and maturation of fungal rRNA pre

155 '-end caps (including pyrophosphate) and the non-canonical NAD+ cap on mRNAs, and possesses distribut

156 I/SNF-related complexes, the Brd9-containing non-canonical (nc) BAF complex promoted Foxp3 expression

157 er show that Bicra physically binds to other non-canonical ncBAF complex members, including the BRD9/

158 omplement-induced Rab5 effector that induces non-canonical NF-kappaB in endothelial cells (EC).

159 ggest that fetal C4BPA-induced activation of non-canonical NF-kappaB in human placenta may play a cri

160 own as MAP3K14) is the rate-limiting step in non-canonical NF-kappaB pathway activation(2,7), the mec

161 tic agents (small-molecule activators of the non-canonical NF-kappaB pathway).

162 strate that DR3 engages the canonical and/or non-canonical NF-kappaB pathways, and thus stimulates na

163 key regulator proteins of the canonical and non-canonical NF-kappaB pathways, such as Nfkb2, and its

164 Non-canonical NF-kappaB signaling is implicated in infla

165 The non-canonical NF-kappaB signaling may be a central integ

166 Non-canonical NF-kappaB signaling was shown to aggravate

167 The non-canonical NF-kappaB signalling cascade is essential

168 SIX1 and SIX2 are integral components of the non-canonical NF-kappaB signalling cascade.

169 Here we show that activation of the non-canonical NF-kappaB signalling pathway by AZD5582 re

170 n adaptive and innate immune cells, enhanced non-canonical NF-kappaB signalling, and enriched LTbetaR

171 . felis infection enhances the activation of non-canonical NF-kappaB that is associated with increase

172 e was associated with aberrant activation of non-canonical NF-kappaB.

173 nduced by Helicobacter through activation of non-canonical NF-kappaB.

174 r work thus defines an important function of non-canonical NFkB and M-cells in immune homeostasis, in

175 Here we show that epithelial non-canonical NFkB signaling mediated by NFkB-inducing k

176 nts showed higher editing efficiency at most non-canonical NG PAM sites tested, and enabled much more

177 ested, whereas it showed limited activity at non-canonical NGH (H = A, C, T) PAM sites.

178 nsfer is mediated by the symbiosis-specific, non-canonical NPC2 proteins, which gradually accumulate

179 Our data suggest that non-canonical NPCs are adapted to the symbiosome environ

180 attering as a pathway to solve and determine non-canonical nucleic acid motifs and reveal the variabi

181 ng experimental evidence suggests that these non-canonical nucleic acid structures form in vivo and p

182 Finally, the uncharacterised, non-canonical ORFL147C protein was found to interact wit

183 was virtually undetectable, indicating that non-canonical p38 activation may exist for other GPCRs.

184 Overall, these data support a non-canonical p53 function in the regulation of adipocyt

185 e metastasis of neighboring cancer cells via non-canonical paracrine-mediated activation of GLI activ

186 nists stimulate p38 MAPK activation via this non-canonical pathway in human endothelial cells derived

187 , we propose a model where light activates a non-canonical pathway mediated by rhodopsin but independ

188 tudies indicate that either the canonical or non-canonical pathways of inflammasome activation have a

189 Non-canonical pathways, by contrast, mainly regulate cel

190 ches are required to robustly identify these non-canonical peptides.

191 e family of bacterial SidE enzymes catalyzes non-canonical phosphoribosyl-linked (PR) serine ubiquiti

192 n are largely unsuitable for the analysis of non-canonical phosphorylation due to their relative inst

193 p avenues for high-throughput exploration of non-canonical phosphorylation in all organisms.

194 lisation probabilities, the number of unique non-canonical phosphosites is approximately one-third of

195 plants that might play an important role in non-canonical poly(A) site choice in response to abiotic

196 PAPD5 is a non-canonical polymerase that oligoadenylates and destab

197 he V990M mutation affected the gating of the non-canonical pore of TRPM3, resulting in large inward c

198 a ribosomal precursor processed by 49 mostly non-canonical posttranslational modifications.

199 volution of core components of canonical and non-canonical PRC1 complexes in animals.

200 ere, we report that TFEB also orchestrates a non-canonical program that controls the cell cycle/VEGFR

201 Here, we identify a non-canonical promoter element that plays a key role.

202 he correction of pathological mutations with non-canonical protospacer-adjacent motifs.

203 cted concept that GSDMC/caspase-8 mediates a non-canonical pyroptosis pathway in cancer cells, causin

204 type CRCs identified associations of NF1 and non-canonical RAS/RAF aberrations with primary resistanc

205 esponding to 6368 ortholog groups) and 3,651 non-canonical RBPs without known RBDs.

206 by cold in a tissue-specific manner through non-canonical RdDM, involving RDR6 and AGO6.

207 l Hh-GLI1 signaling, and additionally in the non-canonical regulation of GLI1 through pERK1/2.

208 exity and interplay of the components of the non-canonical renin-angiotensin system, and discuss the

209 Angiotensin-(1-9), a component of the non-canonical renin-angiotensin system, has a short half

210 Non-canonical residues, caps, crosslinks, and nicks are

211 ALN paternal allele expression is imposed by non-canonical RNA-directed DNA methylation (RdDM) of the

212 The selective enrichment of non-canonical RNA-editing events within MNR adjacency pr

213 Our findings demonstrate a non-canonical role for a caspase in promoting developmen

214 Taken together, our findings uncover a non-canonical role for E2F4 that provide insights into t

215 In summary, our work identifies a non-canonical role of caspase-8 exploited by cancer cell

216 ain aminoacyl t-RNA synthetase have multiple non-canonical roles in both transcription and translatio

217 In addition, oligodendrocytes play diverse non-canonical roles including axonal metabolic support a

218 urther place complosome activities among the non-canonical roles of other intracellular innate danger

219 s, p21(CIP) and p16(INK4a), and results in a non-canonical senescence-associated secretory phenotype,

220 we show that SF3B1K700E spliceosomes utilize non-canonical sequence variants (at position -1 relative

221 40% of the total miRNA pool was composed by non-canonical sequences.

222 rived from individuals who were positive for non-canonical serologies (omnibus_p = 9.2 x 10(-17)).

223 several independently expressed antibodies (non-canonical serologies).

224 ps based on the presence of canonical and/or non-canonical serologies.

225 ically, IL-33 triggered calcium influx via a non-canonical signaling pathway specifically in EC cells

226 lutamatergic synaptic strength by engaging a non-canonical signaling pathway that interferes with ves

227 Recently, we uncovered a non-canonical signalling mechanism for the plant hormone

228 ICRF193-dependent manner by NSE2 at a novel non-canonical site (K1520) and that K1520 sumoylation is

229 tides to prevent RNA-primed transcription at non-canonical sites in the mitochondrial genome, sheddin

230 reduces the poly(A) site usage within these non-canonical sites.

231 h its endogenous DNA targets, dependent on a non-canonical small RNA (scaRNA) and tracrRNA.

232 imal Cascade utilizes previously overlooked, non-canonical small subunits to stabilize R-loop formati

233 Here we demonstrate that the non-canonical SMC family protein, SmcHD1, which is impor

234 otropic phase behavior and provide access to non-canonical soft matter Frank-Kasper A15 and sigma pha

235 canonical hydrogen bonds in some regions and non-canonical stacking in others, whereas (CG)12 forms a

236 We show that NTEs with non-canonical start codons govern the subcellular protei

237 hosphorylation, raising the possibility that non-canonical STAT function may contribute to the effect

238 Our study identifies non-canonical STAT3 activation as the crucial signalling

239 t may facilitate nucleotide exchange), and a non-canonical state in which the G protein is rotated by

240 In the non-canonical state, NTSR1 exhibits features of both act

241 and non-pyroptotic functions in response to non-canonical stimuli.

242 iation and apoptosis, but it also exhibits a non-canonical structural role in poising chromatin for c

243 Thus, these studies reveal a non-canonical, structural role for the IP3Rs and direct

244 Non-canonical structures are linked to this expansion.

245 RNA sequences rich in guanine (G) can adopt non-canonical structures known as G-quadruplexes (G4).

246 d SteE then forces GSK3 to phosphorylate the non-canonical substrate signal transducer and activator

247 is experiments, we show that YcjX utilizes a non-canonical switch 2' motif not previously observed in

248 mon synapse configurations are less-studied, non-canonical synapse types that are prevalent throughou

249 a first step in the design of bacteria with non-canonical "synthetic" cell walls.

250 ve de novo production of cinnamoyltropine, a non-canonical TA.

251 conclude that multiple GPCR agonists utilize non-canonical TAB1-TAB2 and TAB1-TAB3-dependent p38 acti

252 commonly phosphorylated motif in mitosis (a non-canonical target of Cyclin B-Cdk1), and of BCL9L at

253 We identified a set of non-canonical targets in human cells that are specifical

254 (OPCs), we demonstrate that HIF1a activates non-canonical targets to impair generation of oligodendr

255 Non-canonical targets, including Ascl2 and Dlx3, were su

256 ary mitotic death pathway is engaged through non-canonical telomere deprotection, regulated by TRF2,

257 the catalytic activity of this new family of non-canonical, terpene cyclases.

258 oliferation; suggesting the involvement of a non-canonical Tgfb signaling pathway.

259 EI expression levels are regulated through a non-canonical TGFbeta signaling pathway by 3'-UTR-mediat

260 at fat-specific cold mimetics via activating non-canonical thermogenesis protect against obesity.

261 rises bipolar minifilaments(8-10) as well as non-canonical three-legged configurations.

262 idual transposon mRNAs, Mael helps Rhi drive non-canonical transcription of piRNA precursors without

263 itogen-activated protein kinase (MAPK) via a non-canonical transforming growth factor-beta-activated

264 equesters RNA-binding proteins(5) before its non-canonical translation into neural-toxic dipeptide pr

265 cted cells by increasing DRiP synthesis from non-canonical translation of "untranslated" regions and

266 nderstanding how peptides are generated from non-canonical translation of defective ribosomal product

267 We show that the non-canonical tubulin Tuba8, transiently expressed in co

268 d analytical approach that characterizes the non-canonical tumor HLA peptide repertoire, by incorpora

269 Recent studies suggest that non-canonical tumor-specific HLA peptides derived from a

270 3D motion, the model explains the strikingly non-canonical tuning present in existing electrophysiolo

271 itecture of SM N100, introducing the role of non-canonical ubiquitination sites and deepening our mol

272 ts weak deubiquitinase activity towards this non-canonical ubiquitination.

273 epressed in KRAS(G12D) tumors by functional, non-canonical upstream open reading frames in its 5' unt

274 ally located force generator, and indicate a non-canonical use of cadherin on the basal side of an ep

275 ozygous, potentially pathogenic variant in a non-canonical, well-conserved splice site within TRAPPC4

276 R-127-5p, which results in the modulation of non-canonical Wnt and EGFR pathways.

277 In the current study, we show that Wnt5A, a non-canonical Wnt ligand that drives a metastatic, thera

278 The non-canonical Wnt ligand Wnt5a, secreted by proximal str

279 Wnt ligands belonging to both canonical and non-canonical Wnt pathways regulate membrane potential s

280 ddressed the interplay between canonical and non-canonical Wnt pathways.

281 e developed a light-activated version of the non-canonical Wnt receptor Frizzled 7 (Fz7) to analyze h

282 ling through beta-catenin, signaling via the non-canonical Wnt receptor Ryk regulates interneuron cel

283 Fz7) to analyze how restricted activation of non-canonical Wnt signaling affects directed anterior ax

284 Our findings highlight how non-canonical Wnt signaling coordinates collective cell

285 ntrast to the situation in epithelial cells, non-canonical Wnt signaling functions permissively rathe

286 Non-canonical Wnt signaling plays a central role for coo

287 to transactivate trimeric G-proteins during non-canonical Wnt signaling via a novel G-protein bindin

288 Raralpha inactivation leads to inhibition of non-canonical Wnt signaling, without affecting the canon

289 itive endoderm (PrE) and can be regulated by non-canonical Wnt signaling.

290 his collective cell behavior is regulated by non-canonical Wnt signaling.

291 he central blastoderm by local activation of non-canonical Wnt signalling within the blastoderm margi

292 These pathways include canonical and non-canonical WNT signalling, the Hippo-Yes-associated p

293 o pluripotency of MSCs reduced circFOXP1 and non-canonical Wnt, whereas canonical Wnt was boosted.

294 These data reveal an important role for non-canonical Wnt-Ryk signaling in establishing the corr

295 le spatiotemporally restricted activation of non-canonical Wnt-signaling drives cell polarization in

296 Epigenetic-mediated activation of non-canonical WNT/beta-catenin/MMP signaling and a YY1/l

297 lateral side, suggesting that endocytosis of non-canonical Wnt/receptor complexes preferentially take

298 work (GRN) by canonical Wnt/beta-catenin and non-canonical Wnt1/Wnt8-Fzl5/8-JNK signaling.

299 induced pluripotent stem cells and show that non-canonical WNT4 signalling drives the metabolic matur

300 um and signal through Bmp morphogens and the non-canonical Wnt5a ligand.