ライフサイエンスコーパス: non-classical

1 assembled MHCI proteins, both classical and non-classical.

2 the plasmon in such stacks is unambiguously non-classical.

3 m evolution of a photon, then the exciton is non-classical.

4 , characterized as classical inflammatory or non-classical.

5 ated with bottom-up model derivation for the non-classical 2D COF crystallization processes.

6 iption, temporal order is expected to become non-classical-a scenario beyond the scope of current the

7 g has been increasingly investigated for its non-classical actions in stimulation of innate immunity

8 esistance to kynurenic acid which suggests a non-classical activation of NMDA receptors by mitochondr

9 AtAGP30 is a non-classical AGP core protein from Arabidopsis that is

10 This cDNA, DcAGP1, encodes a new class of non-classical' AGP with strong similarity to a family of

11 Identification of novel, non-classical and druggable AR-target genes may provide

12 as due to an increase in absolute numbers of non-classical and intermediate monocytes.

13 changed over time with an increasing rate of non-classical and subclinical phenotypes.

14 indicate that monocytes (both classical and non-classical) and CD4(+) cells (T(h)1 and T(h)2) were i

15 Adhered CCR2(+) cells were mostly the non-classical, anti-inflammatory Ly6C(lo) type, and they

16 emble antithrombin III-binding classical and non-classical anticoagulant polysaccharide structures fo

17 nhibited by classical antifolates but not by non-classical antifolates or biopterin.

18 down of TbFT1-3 increased susceptibly to the non-classical antifolates pyrimethamine and nolatrexed.

19 s antigen-dependent activation, primarily by non-classical antigen-presenting cells.

20 epigenetically primed for regulation by the non-classical AP-1 family member BATF.

21 nduced cell death may be occurring through a non-classical apoptosis pathway that is not dependent on

22 three-dimensional suprastructures which have non-classical architectures (non-Archimedean/Platonic so

23 ods for the direct synthesis of sulfonylated non-classical arene bioisosteres, which could improve th

24 tuitive view on how the Coulomb interaction, non-classical aspects, the strength of the driving field

25 and/or persistent collateral sensitivity to non-classical BCR-ABL1 drugs arises in emergent tumor su

26 (or triggered) single-photon sources exhibit non-classical behaviour in that they emit, with a high d

27 This non-classical behaviour of the electrical conductance an

28 the Bell inequality was designed to test for non-classical behaviour without assuming the applicabili

29 was inactive against glycine receptor, its "non-classical" binding sites on alpha7 nAChR should be w

30 rminal alkyne moiety proved to be a suitable non-classical bioisosteric replacement for the higher ha

31 luster containing B. inopinata and the other non-classical Brucella species but also revealed signifi

32 henotypes are due to loss-of-function in the non-classical cadherin celsr1a.

33 We have identified a non-classical cadherin, Cad74A, as a putative adhesion g

34 Thus, non-classical cadherins that function in adhesion are li

35 tivate endothelial nitric oxide (eNOS) via a non-classical, "calcium-independent" pathway.

36 c molecules, mostly lipids, presented by the non-classical CD1 family (CD1a-e).

37 cially for proinflammatory and profibrogenic non-classical CD14 + CD16+ monocytes.

38 osely with circulating monocytes, especially non-classical CD14+ CD16+ monocytes, which were found to

39 .001), whilst intermediate (CD14++CD16+) and non-classical (CD14+CD16+) monocytes increased (both p <

40 Intermediate and non-classical cells are known to exhibit varying levels

41 delta T-cell receptor and its ligand, T22, a non-classical class I major histocompatibility complex (

42 isms of regulation is the recognition of the non-classical class I MHC molecule HLA-E, in complex wit

43 HLA-E is a non-classical class I MHC protein involved in innate and

44 Here, we show that the non-classical class I-like major histocompatibility comp

45 ctive peptides is generated by processing at non-classical cleavage sites that do not contain basic r

46 Neither the peptidases responsible for non-classical cleavages nor the compartment involved in

47 t, I argue that there is no agreement within non-classical cognitive science as to whether one should

48 te of an atomic memory is transformed into a non-classical collective atomic state by Rydberg-level i

49 k interactions do not allow fast creation of non-classical collective states.

50 proband with femorogluteal lipodystrophy and non classical congenital adrenal hyperplasia, and an ess

51 s stages of differentiation, we identified a non-classical consensus splicing sequence in intron 2 ad

52 s contribution, we investigate the bipartite non-classical correlations (NCCs) of a system formed by

53 Here we report non-classical correlations between single photons and ph

54 Here we present the observation of non-classical correlations between two photons in the ne

55 At the macroscopic optical-field level non-classical correlations can also be important, as in

56 Compared to previous investigations of non-classical correlations for photon pairs produced in

57 ton pairs-discrete light quanta that exhibit non-classical correlations-play a crucial role in quantu

58 s demonstrate that it is possible to harness non-classical crystal growth to fabricate organic molecu

59 Non-classical crystallisation (NCC) pathways are widely

60 The results shed new light on non-classical crystallization mechanisms and have implic

61 Thromboxane synthase (TXAS) is a "non-classical" cytochrome P450.

62 ferating cell nuclear antigen (PCNA) and two non-classical DNA polymerases, Rev1 and DNA polymerase e

63 l theories with maximal certainty have their non-classical dynamics absolutely restricted to only the

64 also plays a positive role as the enabler of non-classical dynamics in an interferometer.

65 ry minimizes certainty in return for maximal non-classical dynamics.

66 abilistic theories this heavily curtails the non-classical dynamics.

67 ion processing and metrology applications, a non-classical emitter of single photons is required.

68 his increase in expression was mostly due to non-classical enhancer activity within the intron, and m

69 hways of metastasis along with classical and non-classical epithelial-mesenchymal transition.

70 of classical ERalpha-regulated genes, while non-classical ERalpha-regulated genes were less impacted

71 Classical and non-classical estrogen and mineralocorticoid receptors w

72 synaptotagmin-1 is able to utilize the FGF-1 non-classical exocytotic pathway and that the release of

73 s: 1) classical (malabsorption syndrome); 2) non-classical (extraintestinal and/or gastrointestinal s

74 symptoms in men and women with classical and non-classical Fabry disease (FD).

75 After nucleated in this non-classical fashion, individual droplets grow until be

76 ified as classical fast spiking (n = 10), as non-classical fast spiking (n = 3, including one burst-f

77 nstrate a mechanism that is able to transfer non-classical features imprinted on the state of a matte

78 tum physics relies on detectors sensitive to non-classical features of systems, enabling precise test

79 in biology requires clear identification of non-classical features that these processes can exhibit

80 Here, we describe a non-classical fibrin clotting mechanism mediated by SARS

81 om temperature can manifest and benefit from non-classical fluctuations of collective pigment motions

82 This supports non-classical formation of aragonite within both a synth

83 y, alerts us to the increasing evidence for 'non-classical' forms of protein translocation that may i

84 we experimentally reveal that the predicted non-classical function of CBX7 is biologically significa

85 the first computational framework to predict non-classical functions and cofactors of a given HMR, ba

86 Recently, several non-classical functions of histone modification regulato

87 in ChIP-seq data-rich cell types and predict non-classical functions of HMRs.

88 with special focus on the recently described non-classical functions of PcG complexes in stem cells a

89 s highly variable and includes classical and non-classical gastrointestinal symptoms, extraintestinal

90 prisingly, paternally-expressed genes of the non-classical gene imprinted network were strikingly enr

91 controlling adaptation to such environments, non-classical genetic effects are likely to be observed.

92 e tomographically verify preservation of the non-classical Greenberger-Horne-Zeilinger state.

93 Human leucocyte antigen-G (HLA-G) is a non-classical HLA class I molecule demonstrated original

94 ally identifies the dosage contribution of a non-classical HLA gene to disease etiology.

95 risk of a synonymous mutation at HLA-DOA, a non-classical HLA gene, on anti-citrullinated protein au

96 LA class I-derived peptides displayed on the non-classical HLA-E for recognition by CD94-NKG2 recepto

97 The BBB selectively allows classical and non-classical hormones entry to and exit from the CNS, t

98 Expression of the non-classical human leukocyte antigen-G (HLA-G) promotes

99 Computational studies reveal that a non-classical hydrogen bond between iodide and the aldeh

100 Herein, we highlight that non-classical hydrogen bonding (NCHB), likely resulting

101 Here, we will discuss non-classical immunoregulatory properties of C3 and C5 c

102 The presence of the observed strong non-classical induction force implied that energies of n

103 hat the heritable variations are produced by non-classical inheritance systems, including non-DNA inh

104 tein inhibitor, DARPin E2_79, acts through a non-classical inhibition mechanism, not only blocking Ig

105 itial state of sufficient purity to create a non-classical, inseparable state.

106 both classical TPRT-mediated insertions and non-classical insertions.

107 These results suggest that SAMHD1 is a non-classical interferon-stimulated gene regulated throu

108 Chloride intracellular channels (CLIC) are non-classical ion channels lacking a signal sequence for

109 es for high-fidelity quantum simulations and non-classical itinerant photon generation(12,13).

110 h atypical language laterality also included non-classical language areas such as the superior and mi

111 chip that can receive, image and manipulate non-classical light over free space.

112 he demonstration of these capabilities using non-classical light remains challenging.

113 providing direct evidence for a solid-state non-classical light source, this result proves that a si

114 are one of the most promising platforms for non-classical light sources and quantum logic gates whic

115 Non-classical light sources offer a myriad of possibilit

116 uantum electrodynamic techniques or prepared non-classical light sources.

117 t on-chip photon correlation measurements of non-classical light.

118 The non-classical major histocompatibility complex (MHC) hom

119 Disruption of the non-classical Major Histocompatibility Complex (MHC) Ib

120 ss potential implications on the notion that non-classical major histocompatibility complex (MHC) mol

121 The protein HLA-E is a non-classical major histocompatibility complex (MHC) mol

122 altering and/or mimicking: (1) classical and non-classical major histocompatibility complex (MHC) pro

123 tructural characterizations of classical and non-classical major histocompatibility complex class II

124 It encodes the beta subunit of the non-classical major histocompatibility complex class II

125 Qa-1 epitopes, the peptides that bind to non-classical major histocompatibility complex Ib Qa-1 m

126 at recognize lipid antigens presented by the non-classical Major Histocompatibility Complex molecule

127 d mTOR pathways, and provide an example of a non-classical means for SHH-mediated protein regulation

128 These results together reveal a non-classical mechanism by which VDR acts as a c-Jun/AP-

129 As such, MS-PCET can function as a non-classical mechanism for homolytic bond activation, p

130 The present study describes a non-classical mechanism that does not require internaliz

131 /ZMYND10) are very frequently inactivated by non-classical mechanisms such as promoter hypermethylati

132 ion could be mediated by allosteric or other non-classical mechanisms.

133 turn inhibits c-Jun-dependent cell death by non-classical mechanisms.

134 Calpain 5 (CAPN5) is a non-classical member of the calpain family.

135 4 ligands, of which classical metal-binding, non-classical metal-binding, non-metal-binding and metal

136 However, little is known about how these non-classical MHC class I (MHCI) molecules diverged from

137 epending on type, interact with classical or non-classical MHC class I antigens of the adaptive immun

138 ure NKT cells are positively selected by the non-classical MHC class I molecule CD1d, which is expres

139 -invariant T cell receptor restricted to the non-classical MHC class I molecule MR1 presenting bacter

140 natural killer-cell receptor), often bind to non-classical MHC class I molecules, such as the human M

141 ymorphism (11 alleles), as was expected of a non-classical MHC gene.

142 We and others have demonstrated that the non-classical MHC I molecule HLA-E can present pathogen-

143 assical MHC (MHC-Ia), we have shown that the non-classical MHC molecule (MHC-Ib) H2-M3 was a ligand f

144 cells recognize glycolipids presented by the non-classical MHC molecule CD1d.

145 hat senescent dermal fibroblasts express the non-classical MHC molecule HLA-E, which interacts with t

146 The non-classical MHC molecule T22 represents the best chara

147 HLA-F, a non-classical MHC molecule, is not known to present pept

148 to the medulla, included cells restricted by non-classical MHC molecules and expressed the receptor N

149 ovel insights into the role of classical and non-classical MHC molecules in graft rejection.

150 microbial non-peptidic antigens presented by non-classical MHC MR1.

151 -DRB exon 2 alleles and characterized a new, non-classical, MHC II gene (MHC-DOB) for white-tailed de

152 bond strengths and a recent structure of the non-classical MHCII protein HLA-DO reveal changes in the

153 overview of the regions within classical and non-classical MHCII proteins that display conformational

154 w that Salmonella can exploit mammalian cell non-classical microRNA processing machinery to further p

155 non-classical states of motion by capturing non-classical microwave signals prepared by the most coh

156 recognize antigens presented by a variety of non-classical molecules.

157 Non-classical monoamine recognition evolved in two steps

158 rategies directed towards enhancing Ly6c(Lo) non-classical monocyte function may mitigate the detrime

159 However, acute nociception and DRG non-classical monocyte numbers were reduced in CX(3)CR(1

160 n blood contains classical, intermediate and non-classical monocyte subsets that each express charact

161 IKV infection was observed, in contrast to a non-classical monocyte-mediated M2-skewed immunosuppress

162 : 0.395; 95 %CI: 0.260-0.530; p < 0.001) and non-classical monocytes (beta: 0.629; 95 %CI: 0.516-0.74

163 In addition, although the frequencies of non-classical monocytes (CD14(+)CD16(+)) were not signif

164 classical monocytes (CD14(hi)/CD16(-)), and non-classical monocytes (CD14(low)/CD16(+)) compared to

165 l monocytes (Ly6c(Hi)) and pro-reparative or non-classical monocytes (Ly6c(Lo)).

166 ats by LPS response profiles consistent with non-classical monocytes and alternatively-activated macr

167 CD16(-) classical monocytes, CD14(+)CD16(++) non-classical monocytes and CD14(++)CD16(+) intermediate

168 The DCs originate from non-classical monocytes and form stable, cognate interac

169 ing of blood monocyte subsets indicates that non-classical monocytes are biased progenitors of altern

170 Here, we demonstrate that circulating non-classical monocytes are directly recruited to polyme

171 Elevated classical and non-classical monocytes are potential risk factors for A

172 a previously unknown role for blood-derived non-classical monocytes as contributors to alternatively

173 t cancer, and levels of these miRs in CD115+ non-classical monocytes correlates with metastatic tumor

174 in Ly6c(Hi) classical monocytes and Ly6c(Lo) non-classical monocytes determine susceptibility to peri

175 advanced stages of PAOD, while classical and non-classical monocytes displayed no such trend.

176 We uncover a role for non-classical monocytes in B-ALL survival, and demonstra

177 inated more frequently from intermediate and non-classical monocytes in CF patients.

178 n exacerbated M2-skewed immunosuppression of non-classical monocytes in conjunction with a global sup

179 Pharmacologic inhibition of Ly6c(Lo) non-classical monocytes in this setting restored suscept

180 LFA-1-dependent endothelial surveillance by non-classical monocytes may detect immune complexes thro

181 Glomerular endothelium and non-classical monocytes overexpressed a distinct chemoki

182 Higher levels of non-classical monocytes pre-fistuloplasty were associate

183 recruitment kinetics and functional role of non-classical monocytes remains unclear.

184 Non-classical monocytes surveyed the glomerular endothel

185 ll molecule FTY720 recruits S1PR3-expressing non-classical monocytes that support vascular remodeling

186 vation and P2X7R activity were comparable in non-classical monocytes to other subsets: their diminish

187 re provided evidence that both classical and non-classical monocytes undergo periods of intravascular

188 t to RRV-mediated liver injury when Ly6c(Lo) non-classical monocytes were expanded.

189 During NTN, non-classical monocytes were recruited first, but subseq

190 ranscriptional profile expressed by Ly6c(Lo) non-classical monocytes, and a physiologic abundance of

191 s, where there is a physiologic expansion of non-classical monocytes, and in the neonatal liver upon

192 g of peripheral blood revealed reductions of non-classical monocytes, and subsets of NK and T lymphoc

193 Here we show that primary human non-classical monocytes, exposed to LPS or LPS + BzATP (

194 intermediate monocytes, and CD14(+)CD16 ++: non-classical monocytes.

195 nd IL-18 along with more robust induction of non-classical monocytes.

196 CyTOF analysis revealed a reduction in non-classical monocytes.

197 pression, cytokine and chemokine levels, and non-classical monocytes; 3) gene signature of leukocyte

198 moment that is responsible for the observed non-classical morphologies.

199 An archetype of such non-classical motion is tunnelling through an energy bar

200 a single atom unequivocally demonstrated the non-classical nature of radiation.

201 ffect of directed emission combined with the non-classical nature of the emitted light.

202 Schwarz inequality is clear evidence for the non-classical nature of the mechanical state generated.

203 per-resolution techniques which leverage the non-classical nature of the optical signals radiated by

204 LacNAc (slan) antigen identifies a subset of non-classical (NC) monocytes in the bloodstream, namely

205 Recently, examples of non-classical neurotransmission have also been reported,

206 ha, but repressed by treatment of cells with non-classical NF-kappaB activators, anthracyclins and UV

207 previously unsuspected role of M64 within a non-classical NLS may contribute to its invariance among

208 "Non-classical" notions consider formation pathways of cr

209 aused by the impaired function of a flanking non-classical nuclear localization signal (NLS).

210 ave been proposed as intermediate species in non-classical nucleation processes.

211 undamental and mechanistic understanding of "non-classical" nucleation and crystallization in this Pe

212 Providing an outline of "non-classical" nucleation, we demonstrate that prenuclea

213 nsformation of a classical state to a highly non-classical one and a Gaussian state to a non-Gaussian

214 ent, and stable generation and processing of non-classical optical states.

215 s evolved a new way to recognize amines in a non-classical orientation.

216 g and antibunching simultaneously is a fully non-classical outcome of the wave-particle duality of ph

217 iO(2) , an oxide/metal inverse catalyst with non-classical oxygen-saturated TiO(2) overlayers were ob

218 Transglutaminase 2 (TG2) is secreted by a non-classical pathway into the extracellular space, wher

219 nalyses suggest that SGSs are secreted via a non-classical pathway that involves cleavage into a 300-

220 The proposed model for ClyA represents a non-classical pathway to attack eukaryotic host cells.

221 rs bind to and are internalized by ECs via a non-classical pathway, CAM-mediated endocytosis.

222 g the possibility of its being secreted by a non-classical pathway, which is not clearly understood.

223 athrin machinery and mediate signalling via 'non-classical' pathways.

224 We also identify a subset of non-classical PDAC samples that exhibit the HNF1A/KDM6A-

225 one disorder in the native-state can lead to non-classical Phi(M)-values (Phi(M) > 1) in the rate-det

226 g excited spin qubits can act as a source of non-classical phonons.

227 s are a unique and exciting nanomaterial for non-classical photocatalytic mineralization of organic c

228 Non-classical photon correlations between the emission f

229 ed detector is subsequently used to estimate non-classical photon number states.

230 th by a factor of 7.47 under preservation of non-classical photon-number statistics.

231 The results demonstrate the necessity of a non-classical picture for this class of microscopic syst

232 ta has distinct effects on classical PKC and non-classical PKC activity.

233 nstitutive and autonomous Ca(2+)-independent non-classical PKC activity.

234 ificity for moesin and with activation under non-classical PKC conditions.

235 of facilitating selection of the appropriate non-classical polymerase and polymerase-switching events

236 In the symptomatic group the non-classical prevailed over the classical phenotype (66

237 d cell-coupling in the proximal kidney via a non-classical pro-fibrotic mechanism and the data provid

238 f these steroid-peptide links, especially on non-classical progesterone actions through allopregnanol

239 is a critical tool for understanding how the non-classical properties of matter might be functionalis

240 suring the Husimi Q function and confirm the non-classical properties of these transient states by ca

241 therefore suggest that investigation of the non-classical properties of vibrational motions assistin

242 lar cartilage vesicles (ACVs) participate in non-classical protein secretion, intercellular communica

243 lization of radicals facilitate the observed non-classical quasi-metallic behaviour.

244 erfamily can participate in the catalysis of non-classical reactions.

245 Models seeking to explain these non-classical receptive field (nCRF) effects in terms of

246 results reveal possibly a context-dependent, non-classical regulatory role for SOX9.

247 ssical class I genes, two CD1 genes and some non-classical Rfp-Y genes are known in chicken, and all

248 o Here, we show that AChE plays an essential non-classical role in vertebrate gut morphogenesis.

249 To explore the 'non-classical' role of AChE, we examined embryos mutant

250 te that AChE is dispensable for its proposed non-classical roles in muscle fiber formation and sensor

251 n addition, AChE is thought to play several 'non-classical' roles that do not require catalytic funct

252 n processing T. gondii oocysts, in line with non-classical routes of infection, and open new perspect

253 time, the near-to unfathomable potential of "non-classical" routes for the synthesis of inorganic fun

254 Perhaps most excitingly, phenoxazines have "non-classical" RTA activity, where they trap >2 peroxyl

255 eveloped to facilitate the discovery of such non-classical secreted proteins; however, the existing m

256 Among all the secreted proteins, 'non-classical' secreted proteins are difficult to identi

257 r the development of improved predictors of 'non-classical' secreted proteins from sequence data.

258 -quality dataset of experimentally verified 'non-classical' secreted proteins, which we then used to

259 ain, is believed to play a major role in the non-classical secretion of the aFGF release complex medi

260 s this regulatory element with classical and non-classical secretion pathways.

261 Non-classical secretory vesicles, collectively referred

262 myeloid LKB1 deficient mice had AMs with a 'non-classical' (SiglecFlowCD11bpos) phenotype.

263 ion of two gold centers to enforce selective non-classical sigma,pi-activation with bifunctional subs

264 miR-744 also enhanced the activation of non-classical signal components, such as ERK and p38.

265 ignaling, but may activate MAPK to occur via non-classical signaling intermediates.

266 peutic target due to its ability to activate non-classical signaling pathways involved in neuroprotec

267 mediated chemoattraction represents a novel, non-classical signaling system that has therapeutic pote

268 eriochlorophylls coordinated by LH2 act as a non-classical single-photon emitter.

269 /junction-enriched neighborhood, revealing a non-classical small molecule inhibitory mechanism based

270 acellular cysteine protease belonging to the non-classical small optic lobe (SOL) family of calpains,

271 n superpositions of spin configurations with non-classical spin correlations, complicating interpreta

272 This allows measurement-based non-classical state preparation, which has been applied

273 Preparation of these non-classical states in resonators is non-trivial due to

274 s process, it should be possible to generate non-classical states of light by measurement and perform

275 To create and manipulate non-classical states of light for quantum information pr

276 The generation of non-classical states of light is of fundamental scientif

277 The deterministic generation of non-classical states of light, including squeezed states

278 rthermore, it will enable the preparation of non-classical states of motion by capturing non-classica

279 pid advances in the control and detection of non-classical states of motion, possibly even testing qu

280 Non-classical steady-state phases arising from the inter

281 ized 2NB(+) and unequivocally confirmed its "non-classical" structure inside the ZSM-5 zeolite by ab

282 subdivided into classical, intermediate and non-classical subsets on the basis of surface CD14 and C

283 categorized into classical, intermediate or non-classical subsets, and subsequently differentiated i

284 During the evolution, non-classical superpositions of coherent states (that is

285 likely an amalgamation of multiple existing non-classical theories and highlights the need for the d

286 On one extreme, non-classical theories with maximal certainty have their

287 Indeed, in recent years, with the advent of "non-classical" theories, a primary focus of research con

288 for developing the science and technology of non-classical thermotropic glycolipid mesophases, which

289 that dephasing dynamics itself can exhibit (non)classical traits, depending on the nature of the sys

290 We test various "non-classical" transcription activators (comprising a co

291 ion that is required for the activity of the non-classical translation initiation factor eIF5A.

292 Consumption of fish by dogs enables a non-classical transmission pathway for Guinea worm in Ch

293 ack-donations are crucial in explaining this non-classical trend of the An-L bond lengths in both ser

294 For the first time, we show that this non-classical truncated form of FGFR1 can independently

295 Recently, FH gene was also identified as a "non-classical" tumor suppressor gene and heterozygous mu

296 These include a non-classical tyrosine motif that serves as the signal f

297 Existence of the non-classical VDR pathway was suggested by a requirement

298 the yeast vacuole/lysosome by a constitutive non-classical vesicular transport mechanism, the cytopla

299 ts with autophagosome marker ATG8s through a non-classical VLIR motif.

300 y fibres are primarily due to differences in non-classical, voltage-dependent ion channels, active cl