ライフサイエンスコーパス: non-native

1 ibuted, nitrogen-demanding plants (including non-natives).

2 n result in complexes that are substantially non-native.

3 ater than the effect of non-natives on other non-natives.

4 with increasing native abundance, increasing non-native abundance was associated with steeper decline

5 rected evolution was applied to enhance this non-native activity and create a highly efficient cataly

6 In the current study, we sought to identify non-native AHLs capable of agonizing or antagonizing Cep

7 Recently, the use of fluoropyruvate as a non-native aldolase substrate has arisen as a solution.

8 MP-2 and MMP-9 was redesigned to incorporate non-native amino acids (Flp and mep), resulting in an in

9 e native S. epidermidis AIP signals and five non-native analogs with distinct activity profiles in th

10 that md is independent of initial amounts of non-native ancestry.

11 as used for the focus groups, of whom 4 were non-native and 7 native speakers of English.

12 er thermal treatments needed to give rise to non-native and aggregated species.

13 s are asymmetrical with interactions between non-native and native plants.

14 marine species is limited: just four marine non-native and one cryptogenic species that were likely

15 Macrocyclic products bearing non-native and rigidifying structural motifs, isotopic l

16 ekeepers rely both on native Apis cerana and non-native Apis mellifera, putting bee populations at pa

17 th landscape simplification and increases in non-natives appeared to favour species associated with d

18 ptor (EpoR), to dimerize EpoR ectodomains in non-native architectures.

19 oth timing and plasticity between native and non-natives are hypothesised to promote invasion success

20 r study supports eco-evolutionary novelty of non-natives as a driver of their outsized impacts on com

21 st to previous studies, we observed that the non-native assemblage was surprisingly unresponsive to e

22 For the assessment on non-native backbones, FASPR showed an equivalent or bett

23 Wolbachia to induce parthenogenesis in these non-native backgrounds.

24 ing that hydrolysis yielded an intermediate (non-native) beta-Lg state.

25 he degree of discrimination of native versus non-native binding and the optimization of which becomes

26 The addition of non-native biosynthetic and regulatory components can, h

27 s, NBs lose niche position and relocate to a non-native brain region that is rich in neurosecretory n

28 "Fischer-Tropsch" type coupling of non-native C(1) substrates to higher-order C(>=2) produc

29 ignal type 1 (PTS1) for rapidly sequestering non-native cargo proteins.

30 Finally, we describe the discovery of non-native catalytic functions that may provide future o

31 on in cdc10 mutants by promoting assembly of non-native Cdc11/Shs1-Cdc12-Cdc3-Cdc3-Cdc12-Cdc11/Shs1 h

32 nt to measure the population dynamics of the non-native cladoceran zooplankter Daphnia lumholtzi and

33 rough direction of the enzymes to native and non-native compartments boost the production of target t

34 higher catalyst stability when subjected to non-native conditions compared to the free enzyme, doubl

35 9 targets the SUMOylation of a transitional, non-native conformation of F508del NBD1: (a) its modific

36 ate that the Hsp27-Ubc9 pathway recognizes a non-native conformation of mutant NBD1, which leads to i

37 of a peroxidase active state, which is a key non-native conformational state in apoptosis.

38 The native conformation is stabilized while non-native conformations are destabilized by our optimiz

39 atically create such diverse and well-packed non-native conformations from any protein structure shou

40 effective discrimination of near-native and non-native conformations of protein complexes.

41 the ER stress-dependent secretion of TTR in non-native conformations that accumulate extracellularly

42 the ER stress-dependent secretion of TTR in non-native conformations under these conditions, indicat

43 een performed in detergent, which can induce non-native conformations, or in vivo, where contribution

44 reams, and lowest of all in streams draining non-native conifers.

45 t to recently established methods, which use non-native connections, the Pd-catalyzed prenylation pro

46 X-ray crystallography often requires non-native constructs involving mutations or truncations

47 to be particularly favoured by formation of non-native contacts between the C-termini of the two hel

48 Non-native contacts can, however, influence folding kine

49 was an unstructured N-terminus stabilized by non-native contacts in a conformation that is topologica

50 proteins while accounting for the effects of non-native contacts.

51 y to native language phonemic contrasts than non-native contrasts.

52 riseusin C, 4'-deacetyl-griseusin A, and two non-native counterparts in 11-14 steps is reported.

53 on in transversal tubules (T-tubules) to the non-native crest of the sarcolemma, where their open pro

54 ically-active/native decoys from millions of non-native decoys is one of the major challenges in comp

55 in positive and negative samples (native and non-native decoys) in a decoy set makes the problem even

56 on spread from known introduction points or non-native distributions and ignore the transport proces

57 Remarkably, the introduction of a non-native disulfide bond was critical for formation of

58 ilization of the structure by formation of a non-native disulfide bond.

59 ues, there is the potential for formation of non-native disulfide bonds, making it necessary for the

60 ve a mechanism for the isomerization of such non-native disulfide bonds.

61 utathionylation and S-nitrosylation and form non-native disulfide bonds.

62 hain all-atom simulations predicted that one non-native disulfide in particular, between Cys(32) and

63 characterized, but our understanding of how non-native disulfides are reduced so that the correct or

64 secretion of proteins that are known to form non-native disulfides during their folding.

65 l assay to demonstrate that the reduction in non-native disulfides requires NADPH as the ultimate ele

66 ure as well as those that are not, so-called non-native disulfides.

67 of FPs misfold and fail to fluoresce due to non-native disulphide bond formation.

68 raphic studies of the nucleosomes containing non-native DNA sequences.

69 its native symbiont Breviolum minutum or the non-native Durusdinium trenchii.

70 strate potential consequences of introducing non-native ecosystem engineers to lakes worldwide.

71 died how electron transfer from substrate to non-native electron acceptors can differentially modify

72 lectrostatic interactions, and in particular non-native electrostatic interactions, are involved in f

73 e transitions follow a path involving strong non-native electrostatic interactions, resulting in a tr

74 er, and in particular we uncover the role of non-native electrostatic interactions.

75 es using a chemical cross-linker and removed non-native Env by immunodepletion with non-neutralizing

76 We then examine non-native enzyme activities that have been exploited fo

77 Expression of the non-native enzymes in S7002 afforded unique hydrocarbon

78 robustly exists in dynamic equilibrium with non-native excited state (ES) conformations that have a

79 rete tissue-types in the seed in which these non-native fatty acids preferentially accumulated.

80 rmine covariation in abundance of native and non-native fish species in a highly variable desert rive

81 errae, is known to be negatively impacted by non-native fish, while the threatened toad, Anaxyrus can

82 ften simplify riverine communities and favor non-native fishes, but their influence on life-history e

83 onal uniqueness was higher in native than in non-native fishes.

84 pre-16S rRNA only transiently, likely due to non-native folding of the rRNA during transcription.

85 e free-energy landscape discriminate against non-native folds.

86 rm the predicted benefits of introduction of non-native forms of Rubisco with higher carboxylation ra

87 events shows that bS16 binds both native and non-native forms of the rRNA.

88 yielded peptide assemblies with enhanced and non-native functionalities.

89 Plant nanobionics aims to embed non-native functions to plants by interfacing them with

90 tments hinders efforts to repurpose them for non-native functions.

91 spectral coverage for harvesting light using non-native genetically-encoded light-absorbers, thereby

92 mum extent to which orang-utans representing non-native, geographically and reproductively isolated t

93 ordered, and even well-folded proteins adopt non-native geometries during synthesis, folding, transpo

94 were well folded, including 16 with designed non-native geometries.

95 are narrow, and thus the ability to colonize non-native habitats requires that a number of conditions

96 also reveals the obligatory attainment of a non-native hairpin intermediate (H1) that eventually rea

97 Mutagenesis demonstrated that D46 suppresses non-native Hh precursor autoprocessing and is indispensa

98 nd the reconstitution of desired traits in a non-native host is considered.

99 be the construction of a functional CCM in a non-native host, achieved by expressing genes from an au

100 these differential effects suggest that the non-native host-symbiont pairing is sub-optimal with res

101 plasmid partitioning proteins in native and non-native hosts reveal chromosome-hitchhiking as the li

102 ins and indicate that model systems based on non-native Httex1 sequences may not accurately reproduce

103 king, interactions are mediated by transient non-native hydrogen bonds, which efficiently catch the i

104 y trapped conformations caused by long-lived non-native hydrogen bonds.

105 alysis reveals that kanamycin B stabilizes a non-native, idiosyncratic conformation of the riboswitch

106 se from their high abundance or whether each non-native individual has a disproportionate impact - th

107 the majority seem to be hyperplastic whereby non-native individuals express phenotypes that exceed th

108 ce mate-finding Allee effects in an invading non-native insect population.

109 ound ecological and economic impacts of many non-native insect species, early detection and eradicati

110 Here, we identified a non-native interaction interface on the three-dimensiona

111 The chain flexibility and non-native interactions make diverse binding pathways po

112 models omit the potentially crucial role of non-native interactions.

113 al association results in the formation of a non-native intermediate, separated by a significant free

114 chanisms while shedding light on the role of non-native intermediates which may crucially affect orga

115 W42Q aggregation required formation of a non-native intramolecular disulfide bond but not intermo

116 tigated the ecological effects of native and non-native invaders across levels of biological organisa

117 cies introductions exceeded those induced by non-native invaders.

118 Non-native invasive plants can establish in natural area

119 N ratio, were invaded to a greater extent by non-native invasive species than ectomycorrhizal (ECM) d

120 The discovery of non-native kelp washed up on Antarctic beaches led us to

121 We found non-native kelps, with a wide range of "hitchhiking" pas

122 rogressively favoring mapping of native over non-native language across the first year of life.

123 ss individuals; and (2) that with increasing non-native language proficiency, reading and speech comp

124 riments, showing (1) that in both native and non-native languages, while language production was left

125 nd gp41 was an effective method for removing non-native-like Env.

126 o- and regioselectivity as well as result in non-native linkages that may suffer from instability in

127 w that (i) the MD simulation overstabilize a non-native loop conformation, (ii) eNOE data support its

128 e introduction and range size indicates that non-native marine invertebrate species are not at equili

129 As a result, the risk of harmful non-native marine species being introduced into this cri

130 We review current knowledge of non-native marine species in the Antarctic region, the p

131 Evidence of non-native marine species is limited: just four marine n

132 Non-native marine species will interact with other anthr

133 logical factors that resist establishment of non-native marine species, changes to resistance under c

134 e, which may facilitate the establishment of non-native marine species.

135 Here we use four non-native metabolic reactions to rewire central carbon

136 ity when subjected to chemically similar but non-native metal substitutions is a long-standing puzzle

137 te states of the zinc-bound native CA II and non-native metal-substituted CA IIs, we demonstrate that

138 odulin kinase II-mediated phosphorylation in non-native microdomains and resulted in an elevated ICa,

139 ween the host, the indigenous microbiota and non-native microorganisms, including bacteria, viruses a

140 anding how these same proteins interact with non-native mineral surfaces has important implications f

141 dependent nanomachines that actively reshape non-native, misfolded proteins and assist a wide variety

142 These AHL analogs are the first reported non-native molecules that both directly modulate CepR an

143 ration at pH 6.8 and 8.0 led to formation of non-native monomers and reduced the DH to 75%, but showe

144 in vitro, and use them to infect native and non-native mosquito vectors.

145 Most strikingly, in non-native musicians, neural responses to the formant fr

146 ative speakers, non-native nonmusicians, and non-native musicians.

147 to be hijacked to induce the degradation of non-native neo-substrates using bivalent compounds known

148 al hydroxylation, these enzymes can catalyze non-native nitrile group installation when an azido grou

149 syllable in three groups of native speakers, non-native nonmusicians, and non-native musicians.

150 e formant frequencies of speech, compared to non-native nonmusicians, suggesting that automatic encod

151 In contrast, the other two are non-native oligomers in which the native dimer interface

152 s bad neighbours, but the negative effect of non-natives on natives was around two times greater than

153 around two times greater than the effect of non-natives on other non-natives.

154 en species of aphids (Insecta, Hemiptera) of non-native origin have expanded their range in Europe, h

155 pulation persistence, potentially benefiting non-native over native species under climate change.

156 actor activity with extrinsic signals, while non-native paralogs enforced differentiation even in the

157 MRSA strains have acquired a non-native penicillin-binding protein called PBP2a that

158 CRP, in its non-native pentameric structural conformation, binds to

159 In about 20% of cases plasticity causes non-native phenotypes to diverge from the native phenoty

160 urs at the expense of the ability to process non-native phonemes.

161 chanisms underlying processing of native and non-native phonemic contrasts were recently delineated i

162 e break also disrupted durable learning on a non-native phonetic classification task.

163 n via the native radical transfer pathway or non-native photochemical oxidation, following photosensi

164 and soil physico-chemical properties between non-native Pinus radiata plantations, and nearby native

165 Non-native plant occurrence was negatively related to na

166 mmunity composition: cover of graminoids and non-native plant species significantly increased, and co

167 ecies than in the presence of a neighbouring non-native plant species.

168 itish sites do not differ between native and non-native plant species.

169 ajor habitat types that interactions between non-native plants are asymmetrical with interactions bet

170 ow temporal variation in dominant native and non-native plants impacted the abundance and richness of

171 Non-native plants reached higher abundances than natives

172 In contrast, the performance of non-native plants was five times higher in the presence

173 Non-native plants were always bad neighbours, but the ne

174 t functional groups, and cover of native and non-native plants.

175 ays and challenged them with both native and non-native polyketide substrates.

176 ound that China is the likely source of most non-native populations, with at least four separate intr

177 benefits of stocking-or removing established non-native populations-under a rapidly changing climate.

178 sed on the stabilization of native PPIs, and non-native PPIs have received little consideration.

179 d on the identification and stabilization of non-native PPIs of N protein could be applied toward dru

180 ed a meta-analysis to quantify the effect of non-native prey on native predator populations.

181 Relative to native prey, non-native prey similarly or negatively affect native pr

182 We compute MCS solution-sets for a non-native product indigoidine, a sustainable pigment, i

183 , RASP, SCATD and SCWRL4) on both native and non-native protein backbones.

184 The non-native protein functions also raise the prospect of

185 peptide strategy, we designed a peptide with non-native protein sequence, AP3, which exhibited potent

186 Computationally generated non-native protein structure conformations (or decoys) a

187 Relief from excess levels of non-native proteins by increasing the levels of folding

188 The promiscuous interaction with non-native proteins generates complexes that can form ag

189 e mostly been studied using stably expressed non-native proteins in immortalized cell lines.

190 Molecular chaperones act on non-native proteins in the cell to prevent their aggrega

191 ATPase machine that rescues various forms of non-native proteins including the highly resistant amylo

192 theless, these tools are based on engineered non-native proteins that may (i) express at nonphysiolog

193 erones result in distinct binding modes with non-native proteins that ultimately define the activity

194 cavities that open and close to encapsulate non-native proteins.

195 le hydrophobic segments across the length of non-native proteins.

196 nd up-regulating ERAD components that remove non-native proteins.

197 litate pine establishment in both native and non-native ranges, and that are associated with their in

198 The establishment of non-native Rhizophora mangle along Hawaiian coastlines o

199 management from across Europe, applying the Non-Native Risk Management scheme to defined invasion sc

200 cooperative Rev binding, and also identifies non-native RRE conformational states as new targets for

201 and our analysis of the simulations point to non-native salt bridges between helices as the source, w

202 of interconverting conformers that contain (non-)native secondary structure and lack the tightly pac

203 how that these truncated GFPs can bind other non-native sequences, and this promiscuity invites the p

204 ellulose degradation can be enhanced through non-native SLH domain GHs engineered into the genomes of

205 Non-native speakers of English who hold nursing qualific

206 edicting invasiveness and impact of Invasive Non-Native Species (INNS) by incorporating differences i

207 Invasive non-native species (NNS) are internationally recognized

208 ociated with the successful establishment of non-native species across large geographic regions.

209 abundance of native fish species rather than non-native species and have altered community structures

210 ough such knowledge is fundamental to manage non-native species and mitigate their impacts.

211 icting regions at risk from introductions of non-native species and the subsequent invasions is a fun

212 eillance for the detection and monitoring of non-native species and the timely implementation of cont

213 change, land-use change and introductions of non-native species are key determinants of biodiversity

214 Predictors for the ecological effects of non-native species are lacking, even though such knowled

215 ermine whether the ecological changes due to non-native species are modulated by co-occurring anthrop

216 Changing climate extremes and invasion by non-native species are two of the most prominent threats

217 wever, it remains unclear whether impacts of non-native species arise from their high abundance or wh

218 e was almost no establishment success of the non-native species at moderate dispersal and reduced suc

219 ts at elevations above the invasive range of non-native species can clarify the relative contribution

220 Invasive, non-native species can have tremendous impacts on biotic

221 plant communities may accumulate additional non-native species even if direct interactions between n

222 d global warming in the field and found that non-native species flowered earlier and were more phenol

223 systems inhibit establishment of generalist non-native species from less diverse communities.

224 We found that non-native species had greater negative effects on nativ

225 use across the region, while the fraction of non-native species has increased in the majority of land

226 Invasive non-native species have pervasive impacts on native biod

227 s in the Arctic where the cumulative risk of non-native species introduction is increasing.

228 folded proteins, but only degradation of the non-native species is accelerated.

229 ories suggest that the ecological effects of non-native species may be related to other concomitant a

230 e identified several marine ecoregions where non-native species may have the greatest ecological effe

231 phenological differences between native and non-native species may influence invasion outcomes under

232 would be of value both to bioassessment and non-native species monitoring.

233 on, establishment success and effects of the non-native species on native community structure and eco

234 e and non-native species richness and (2) do non-native species originate from higher diversity syste

235 At both spatial scales, however, nearly all non-native species originated from river basins with hig

236 nd non-Arctic ports that could be sources of non-native species over 15 years (1997-2012) and observe

237 This is the first evidence of non-native species reaching the Antarctic continent aliv

238 the invasibility of native communities by a non-native species represented by core, midrange and per

239 gative relationship exist between native and non-native species richness and (2) do non-native specie

240 vational studies, which find that native and non-native species richness are positively related at br

241 conflicting relationship between native and non-native species richness found at different spatial s

242 A negative relationship between native and non-native species richness in local assemblages was fou

243 r basin characteristics, species traits, and non-native species richness using binomial logistic regr

244 ctive of basin-wide differences in native or non-native species richness.

245 eaty have called for regional assessments of non-native species risk.

246 s is a prerequisite for the establishment of non-native species that become invasive, so knowledge of

247 The risk of introduction of invasive non-native species to the APR is likely to increase with

248 analysis of the ecological effects of marine non-native species with human footprint proxies to deter

249 naturalization and accumulation of multiple non-native species within ecosystems, which is frequentl

250 troductions into the Arctic and dispersal of non-native species within the Arctic.

251 Non-native species' flowering also became more synchrono

252 s by altering competition between native and non-native species, but these effects may depend on biot

253 associated with greater geographic spread of non-native species, implicating phenology as a potential

254 es of native species induced by invasions of non-native species, native species reintroductions might

255 environments also preclude invasions by most non-native species, so identifying especially cold habit

256 Spain where, following the introductions of non-native species, the last resident native species (th

257 Sinanodonta woodiana, a non-native species, was introduced from China.

258 Increases in non-native species, which generally originate from warme

259 irect predation by and resource overlap with non-native species, which occurred in conjunction with h

260 invasions resulting from the introduction of non-native species.

261 ely ignored when forecasting the dynamics of non-native species.

262 xtirpations and preparing for the arrival of non-native species.

263 story-related intraspecific variation of the non-native species.

264 uence local biotic resistance to invasion by non-native species.

265 an temperature to favor the establishment of non-native species.

266 t and indirect interactions among native and non-native species.

267 acts can intensify the ecological effects of non-native species.

268 asions by marine, freshwater and terrestrial non-native species.

269 species even if direct interactions between non-natives species are negative.

270 (native target species) and non-sown (mostly non-native) species.

271 ble regions of proteins and in proteins in a non-native state (i.e. misfolded or unfolded states).

272 This enhancement in the non-native state was due to glycine, as demonstrated by

273 mental and computational methods to describe non-native states at atomic resolution.

274 between the native state and the average of non-native states versus the roughness measured by the v

275 As aggregation can be triggered by non-native states, whose population is not necessarily r

276 s that are most sensitive to the presence of non-native states.

277 Atlantic distribution, casting doubt on its non-native status in the NW Atlantic.

278 Pacific, several genetic traits support the non-native status of C. robusta.

279 ability to confidently ascertain native vs. non-native status of populations, particularly of those

280 n accurately discriminate between native and non-native structural conformations from protein docking

281 e found two reintroduced females were from a non-native subspecies, and have since produced at least

282 uorinase FlA1 for improved conversion of the non-native substrate 5'-chloro-5'-deoxyadenosine (5'-ClD

283 ishing regulatory links between a MAPK and a non-native substrate.

284 Reactions pairing wildtype PKS modules with non-native substrates primarily resulted in poor convers

285 In contrast, non-native substrates were converted by most hybrid modu

286 hibits increased catalytic efficiency toward non-native substrates, especially coprostanol (>200-fold

287 m) of the protein in complex with native and non-native substrates.

288 es in the 2016 checklist that are not trees, non-native, synonyms, or misspellings were removed and c

289 ide assemblies could complex with native and non-native systems to generate novel functional material

290 e demonstrate that PfACTI, when expressed in non-native systems, is capable of binding to and release

291 m with low conformational free energy, while non-native tetraloop/tetraloop-receptor interactions are

292 cell differentiation, and local delivery of non-native therapeutic payloads, such as antibodies, in

293 s are mostly composed of components that are non-native to the human body, such as aluminum salt, bac

294 The catalytic efficiency of P450s in these non-native transformations is however significantly infe

295 n is restored by increased tRNA levels or by non-native tRNAs with exact-matching anticodons.

296 While most researchers have injected non-native ureolytic bacteria to complete bio-cementatio

297 ture herbivores on phylogenetically distinct non-natives vs. natives.

298 sceptibility to mountain pine beetle and the non-native white pine blister rust (WPBR).

299 e have high infection and mortality from the non-native white pine blister rust caused byCronartium r

300 tive species richness prior to invasion by a non-native zooplankter, Daphnia lumholtzi.