ライフサイエンスコーパス: noncatalytic

1 nduced protein kinase SGK1; the mechanism is noncatalytic.

2 e of the substrate, phenylpyruvate (PPA), is noncatalytic.

3 role of VRK1 in neuronal migration is partly noncatalytic.

4 that A3G, A3F, and, to a lesser extent, the noncatalytic A3GC291S block human immunodeficiency virus

5 yze ring formation and thus may be more than noncatalytic accessory proteins.

6 opanoic acids or halides requires the use of noncatalytic acid promoters.

7 The possibilities for noncatalytic activation and the reversibility or irrever

8 ght on the regulation of their catalytic and noncatalytic activities in autophagy initiation.

9 HDAC6 also exerts noncatalytic activities through its interaction with ubi

10 subunits, and the ULK1 complex has essential noncatalytic activities.

11 formation through two genetically distinct, noncatalytic activities: activation of MamE-dependent pr

12 ubiquitin moieties but also strengthened its noncatalytic activity in reducing Lys-63 polyubiquitylat

13 pecificity depends in part on binding of the noncatalytic ADAMTS13 spacer domain to the C-terminal al

14 Crk and CrkL are noncatalytic adaptor proteins necessary for the formatio

15 The organism is highly proteolytic, and noncatalytic adhesin domains of the major proteases, gin

16 binding and catalytic activity but promoted noncatalytic allosteric functions.

17 The noncatalytic alpha domain in the N-terminus appeared to

18 This tight fit places two noncatalytic amino acid residues, Phe-259 and Thr-314, w

19 pression of either catalytic domain with the noncatalytic amino-terminal portion of HUGT1 conferred U

20 on required to induce PDR5 expression to the noncatalytic amino-terminal portion of Psd1.

21 lls lacking PI3Kgamma revealed that only the noncatalytic, amino-terminal domain of p110gamma was nec

22 The conservation of noncatalytic ancillary modules among these enzymes sugge

23 hanistically distinct active vaccines, i.e., noncatalytic and catalytic, for cocaine treatment.

24 e DinB tertiary structure suggests these are noncatalytic, and multiple-sequence alignments indicate

25 fold) in the hemostasis models tested than a noncatalytic antidote that is currently in clinical deve

26 phagosome deliver an array of catalytic and noncatalytic antimicrobial peptides, while activation of

27 coumarin-containing oligonucleotide and the noncatalytic APE1, the dye's absorption spectrum is shif

28 lution, 19 aaRSs expanded by acquiring novel noncatalytic appended domains, which are absent from bac

29 The noncatalytic B subunit of Shiga toxin 1 causes apoptosis

30 bacterial expression system, we demonstrate noncatalytic BADCs facilitate the assembly and activatio

31 act with the redox polymer thus converts the noncatalytic base layer into a catalyst for the electror

32 Hepatocystin functions as the noncatalytic beta subunit of Glucosidase II, an endoplas

33 catalytic alpha subunit and a homologous but noncatalytic beta subunit.

34 ermed "protein kinase C substrate 80K-H" or "noncatalytic beta-subunit of glucosidase II." This prote

35 tion of the APLTs, Dnf1p and Dnf2p, or their noncatalytic beta-subunit, Lem3p, blocked the import of

36 The noncatalytic betaGRPs may be evolutionarily derived from

37 ilico experiments reveal that stoichiometric noncatalytic binding and inhibition can generate a robus

38 In addition, we identify a unique, noncatalytic binding mode for the substrate bicarbonate

39 BTK inhibitors, the mechanism involving the noncatalytic BTK uncovered here may contribute to preexi

40 n a highly conserved region that may serve a noncatalytic but essential function.

41 The enzyme-derived domains appear to be noncatalytic, but they determine the function of the two

42 Their interaction requires the kinase noncatalytic C-lobe domain (KIND) domain of Spire and th

43 t, is increased by interaction with the Nek9 noncatalytic C-terminal domain, suggesting a mechanism i

44 n 3A but also on determinants located in the noncatalytic C-terminal domains of GBF1.

45 Noncatalytic carbohydrate binding modules (CBMs) are com

46 Noncatalytic carbohydrate binding modules (CBMs) fulfill

47 ell wall degrading enzymes generally contain noncatalytic carbohydrate binding modules (CBMs) that fu

48 aTuSC depends on its kinase activity and its noncatalytic central domain.

49 The ability of Pgamma to stimulate noncatalytic cGMP binding to the GAF domains of PDE6 has

50 efect of H257N is not due to perturbation of noncatalytic cGMP binding to the PDE6alpha' GAF domains.

51 ding of the inhibitory gamma-subunit and the noncatalytic cGMP to the GAFa domains of rod PDE6, as we

52 The noncatalytic cGMP-binding characteristics of the H257N m

53 catalytic chain, Trm61, and a homologous but noncatalytic chain, Trm6, repurposed as a tRNA-binding s

54 es not distinguish between the catalytic and noncatalytic clades, and should be revised.

55 Moreover, and consistent with a noncatalytic clearance-based model for inhibition, appre

56 proteolytic ClpP proteins and four different noncatalytic ClpR proteins, with each present in one or

57 ana consists of five catalytic ClpP and four noncatalytic ClpR subunits.

58 (ORF15) C-terminal basic domain binds to the noncatalytic cofactor interaction domain unique to TTLL5

59 In Bacillus subtilis, P protein is the noncatalytic component of ribonuclease P (RNase P) that

60 mprising the C-terminal domains of E2p and a noncatalytic component, E3-binding protein (E3BP), which

61 rotein subunit (Est2p/TERT) and at least two noncatalytic components (Est1p and Est3p).

62 lectivity observed at low temperatures under noncatalytic conditions roughly predicts the regioselect

63 cyl-enzyme complexes has been acquired under noncatalytic conditions.

64 kinase that utilizes its autophosphorylated noncatalytic cryptic polo-box (CPB) to phase separate an

65 Surprisingly, we found that the two noncatalytic Cys around the active center exert an oppos

66 We hypothesize that noncatalytic cysteine pairs in Ero1p sense the level of

67 ted by attenuation of Ero1p activity through noncatalytic cysteine pairs.

68 nt-reversible and irreversible engagement of noncatalytic cysteine residues as well as other amino ac

69 Currently, targeting noncatalytic cysteine residues with acrylamides and othe

70 be unperturbed from pK(a) values of typical noncatalytic cysteine residues.

71 cue flies that express either wild-type or a noncatalytic cysteine-serine mutant PGRP-SC1a, we find t

72 ased ligand design and covalent targeting of noncatalytic cysteines have been employed to develop pot

73 bitors are frequently designed to react with noncatalytic cysteines, many ligand binding sites lack a

74 The noncatalytic DEP-GGL domain of RGS9 antagonized endogeno

75 Here, we show that ADAM11, a transmembrane noncatalytic disintegrin, is the first reported Kv1-inte

76 merization reaction, explain the role of the noncatalytic divalent cation in 6 RdRp, and pinpoint the

77 ret these results to suggest that there is a noncatalytic docking site closely associated with PS1-ga

78 l analysis suggests that the WNK1 C-terminal noncatalytic domain mediates vesicle localization.

79 d protein with weak sequence similarity to a noncatalytic domain of class B penicillin-binding protei

80 The amino-terminal noncatalytic domain of MKP-3 is both necessary and suffi

81 ERK binding to the N-terminal noncatalytic domain of MKP3 has been shown to increase (

82 We find that the noncatalytic domain of NHK-1 is crucial for its kinase a

83 cytoplasmic domain, a transmembrane helix, a noncatalytic domain of unknown function, and a catalytic

84 ugu AID catalytic domain to the entire human noncatalytic domain restores activity in mammalian cells

85 motif was identified in the Nek2 C-terminal noncatalytic domain that allows both microtubule binding

86 ish the specific structural features of this noncatalytic domain that are essential to DNA conjugatio

87 ally associates with Cdt1 via its N-terminal noncatalytic domain, a region we had previously shown to

88 to membrane affinity: (1) the amino-terminal noncatalytic domain, and (2) a region with sequence simi

89 gesting that AID features mapping within the noncatalytic domain, but outside the NES, influence its

90 action motif (KIM) within its amino-terminal noncatalytic domain.

91 kinase activity or, surprisingly, any of the noncatalytic domain.

92 had lesions in one of eight residues in the noncatalytic domain.

93 of these large protein complexes consists of noncatalytic domains and subunits, and the ULK1 complex

94 r progressive and accretive proliferation of noncatalytic domains as the Tree of Life is ascended.

95 mechanisms involving both the catalytic and noncatalytic domains determine the distinct substrate sp

96 Defined noncatalytic domains in USP4 and USP15 are known to inte

97 Noncatalytic domains may perform similar functions in ot

98 Additionally, noncatalytic domains of ADAM17 affected the size/shape o

99 We found that noncatalytic domains of ADAM17 did not directly bind the

100 This suggests that noncatalytic domains of ADAM17 play a role in substrate

101 Y(551) phosphorylation, and the role of the noncatalytic domains of Btk in the activation process.

102 Our results suggest a mechanism by which the noncatalytic domains of pollen-specific/enriched RopGEFs

103 ears to interact with both the catalytic and noncatalytic domains of the protease.

104 The noncatalytic domains of TPS1 ensure its targeting to the

105 specific contribution of their catalytic and noncatalytic domains remain elusive.

106 Splicing events retain noncatalytic domains while ablating the catalytic domain

107 ational modification of the protease, intact noncatalytic domains, and its cognate inhibitor.

108 With its noncatalytic domains, DNA-binding regions, and a catalyt

109 ation of the fXIa catalytic domain (CD) from noncatalytic domains.

110 alytic domains and more divergent C-terminal noncatalytic domains.

111 ckets or single residues, and into targeting noncatalytic domains.

112 attributed to multiple interactions between noncatalytic dynein subunits and an array of regulatory

113 een subunits, insights into the functions of noncatalytic editosome proteins, and a global understand

114 nitiate synaptic transmission and CaMKII has noncatalytic effects on presynaptic plasticity.

115 Because this indicated a potential noncatalytic ERK1/2 function, we generated stable lines

116 t DNA polymerase epsilon (Pol epsilon) has a noncatalytic essential role during the early stages of D

117 mutagenesis of ADAMTS-5 identified that the noncatalytic first thrombospondin and spacer domains med

118 BoNT/A(RYM) was noncatalytic for SNAP25 and nontoxic for mice.

119 tive mTP, indicating the conservation of the noncatalytic function across plant species.

120 lin D1 promotes cell cycle progression and a noncatalytic function has been described to sequester th

121 ulatory subunits of cohesin, implicating its noncatalytic function in inactivating cohesin's ability

122 These data show that FIG4 plays a critical noncatalytic function in maintaining lysosomal membrane

123 se observations suggest that SUS has a novel noncatalytic function in plant cells.

124 ing that this mammalian MAPK may also have a noncatalytic function in vivo.

125 The sensitizing mutation also impaired a noncatalytic function of Cdk2 in restricting assembly of

126 increased CDK2 activity associated with the noncatalytic function of CDK4, sequestration of p21(Cip1

127 ganisms, fully effective TLS also requires a noncatalytic function of the Y family polymerase REV1.

128 -dependent UTX stabilization is an essential noncatalytic function of Trr/MLL3/MLL4, suggesting that

129 ere, we report that ERK1/2 also utilizes its noncatalytic function to mediate certain signal transduc

130 idly advancing knowledge of how they perform noncatalytic functions and is enabling the discovery of

131 inhibitors have been shown to influence the noncatalytic functions of active kinases, providing hope

132 plasmic domain to uncouple the enzymatic and noncatalytic functions of CD45 in lymphocytes.

133 Both catalytic and noncatalytic functions of HDACs are being actively studi

134 l surface, inhibiting both the catalytic and noncatalytic functions of LPL.

135 Both catalytic and noncatalytic functions of SHP2 are required for Fyn acti

136 e that these "pseudogenes" have alternative, noncatalytic functions that have not yet been uncovered.

137 that the EVH1 domain of Spred1 binds to the noncatalytic (GAPex) portion of the GAP-related domain (

138 m scale, and was not exceptional compared to noncatalytic groups.

139 Human CBS possesses a noncatalytic heme cofactor with cysteine and histidine a

140 The noncatalytic hemopexin domain of MMP9 binds to the low-d

141 on of both catalytically active ISA1 and the noncatalytic homolog ISA2.

142 dicots carry a pseudoenzyme PDX1.2 that is a noncatalytic homolog of the PDX1 subunit of the vitamin

143 Under noncatalytic (i.e., no H2 present) reaction conditions,

144 In our search for noncatalytic inhibitors of MT1-MMP, we compared the prot

145 -selective manner through the development of noncatalytic inhibitors of this deubiquitinase to abroga

146 Many noncatalytic Integrator subunits, which are largely disp

147 bunit disulfide bonds were identified in the noncatalytic interaction domains; two in the MAM (meprin

148 ach of the related b and b' subunits, down a noncatalytic interface of the F1 domain and interacts in

149 l of mutual solvation of the partners of the noncatalytic "intimate" ion pair should release the nucl

150 unctional kinase, whereas phosphorylation of noncatalytic intracellular domains is required for recog

151 e second Glu was involved in binding a third noncatalytic ion in bacteriophage RB69 DNA polymerase.

152 mes (ISAs), including the catalytic ISA1 and noncatalytic ISA2, are major starch biosynthesis determi

153 For instance, the potato tuber enzyme has a noncatalytic L subunit that complements an S subunit wit

154 These data illustrate how changes within the noncatalytic lectin domain can alter the recognition of

155 sphorylation of Ser(886) and Ser(999) in the noncatalytic linker connecting the synthetase cores.

156 The noncatalytic lobe is anchored to the motor of the helica

157 t library by targeting imperfectly conserved noncatalytic loop residues and examined the effects on p

158 dentify arylsulfonyl fluorides that target a noncatalytic lysine (Lys162) in eIF4E.

159 by using its catalytic DUB activity or in a noncatalytic manner by inhibiting the E2-conjugating enz

160 ug et al. propose a polyubiquitin-dependent, noncatalytic mechanism by which the deubiquitinase A20 i

161 Our results suggest a noncatalytic mechanism of IKK inhibition by A20 and a me

162 cell wall integrity signaling pathway uses a noncatalytic mechanism to activate the SBF (Swi4/Swi6) t

163 the yeast cell wall integrity pathway uses a noncatalytic mechanism to activate transcription of stre

164 1) and its pseudokinase paralog (Mlp1) use a noncatalytic mechanism to activate transcription of the

165 nts transport activity of MCT1 and MCT4 by a noncatalytic mechanism, while leaving transport activity

166 acellular carbonic anhydrase IV (CAIV) via a noncatalytic mechanism.

167 ase superfamily but signal primarily through noncatalytic mechanisms.

168 JARID2 is a noncatalytic member of the polycomb repressive complex 2

169 In summary, this PTEN noncatalytic missense mutation exposes a core tumor supp

170 Rp from bacteriophage varphi6 uses the bound noncatalytic Mn(2+) to facilitate the displacement of th

171 We find that this displacement releases the noncatalytic Mn(2+), which must be replaced for elongati

172 The additional noncatalytic module is therefore proposed to be required

173 Cel8 (SlCel9C1), with a distinct C-terminal noncatalytic module that represents a previously unchara

174 mounts of sodium hydroxide needed to titrate noncatalytic montmorillonites as compared to the catalyt

175 It was noted that noncatalytic montmorillonites have a higher negative cha

176 In addition, a noncatalytic mutant (D210N) binds tightly to the same ol

177 In addition, structures of a noncatalytic mutant LC/A (Arg362Ala/Tyr365Phe) complexed

178 Noncatalytic mutations affecting the only cyclophilins w

179 We deleted the noncatalytic N and C termini in both GSK-3 isoforms and

180 Like other MKPs, MKP3 consists of a noncatalytic N-terminal domain and a catalytic C-termina

181 Deletion of the noncatalytic N-terminal domain led to loss of nucleolar

182 a dual-specificity phosphatase domain and a noncatalytic NH(2) terminus.

183 atalytic nucleotidyltransferase domain and a noncatalytic oligonucleotide/oligosaccharide binding (OB

184 s not excessively mutagenic, indicating that noncatalytic or other functions of Polkappa could mediat

185 associated with characterizing catalytic and noncatalytic outputs in cells, and describe successes an

186 ain insight into activating mutations in two noncatalytic p110alpha domains-the adaptor-binding and t

187 structural elements at the C terminus of the noncatalytic p51 subunit and the nucleic acid duplex in

188 prised of the catalytic p261 subunit and the noncatalytic p59, p17, and p12 small subunits.

189 nd the apicoplast of the genus Plasmodium, a noncatalytic paralog of ClpP, termed ClpR, has been iden

190 lization in a multisynthetase complex (MSC), noncatalytic peptide appendages, and ancillary functions

191 with either Cik1 or Vik1, both of which are noncatalytic polypeptides.

192 etion of PP1-87B or depletion of a conserved noncatalytic PP1 phosphatase subunit Sds22 leads to defe

193 hK1 and SphK2 depended on both catalytic and noncatalytic properties of Fyn.

194 ensional diffusion along protein surfaces, a noncatalytic protein bridge was inserted between GOx and

195 A variety of catalytic and noncatalytic protein domains are deployed by select micr

196 Nore1, a noncatalytic protein identified by its ability to bind s

197 tribution led us to report the first direct, noncatalytic quantitative observation of hydrogenolysis

198 bstrate, NAD+ and TbSIR2rp1 as follows: 1) a noncatalytic reaction between the deacetylation product

199 the mechanisms of signal initiation of this noncatalytic receptor, as well as to develop therapeutic

200 tive catalytic reduction (SCR) and selective noncatalytic reduction (SNCR) technology.

201 A noncatalytic reduction path on the Au surface and a cata

202 Plks are characterized by a C-terminal noncatalytic region containing two tandem Polo boxes, te

203 to search for proteins with homology to the noncatalytic region of NIMA and identified mixed lineage

204 mic portion of ADAM17 through the C-terminal noncatalytic region of PLK2 containing the Polo box doma

205 mbinant SH3.1 domain of the adaptor molecule noncatalytic region of tyrosine kinase (Nck) can bind to

206 Although it is known that noncatalytic region of tyrosine kinase (Nck) regulates c

207 sults in binding of the adapter protein Nck (noncatalytic region of tyrosine kinase) to the CD3e subu

208 als that the KIM docking site, situated in a noncatalytic region opposite of the kinase catalytic poc

209 of these resemble NIMA within its extensive noncatalytic region, a region critical for NIMA function

210 kinetics led to the identification of three noncatalytic regions in MMP-1 (residues 285-295, 302-316

211 This binding supports the involvement of noncatalytic regions to the tight binding of the MK2:p38

212 s new structure supports the idea that these noncatalytic regions work together as a "conformational

213 Previous work has implicated noncatalytic regions, including the C2 domain and/or WW

214 ull-length kinase and the functional role of noncatalytic regions, we performed hydrogen-deuterium ex

215 Human mutations in KATNB1, which encodes the noncatalytic regulatory p80 subunit of katanin, cause se

216 reconstitution assay system, we now report a noncatalytic requirement for cyclin A-cdk2.

217 tion, a post-translational modification on a noncatalytic residue that increases its peroxidase activ

218 Interestingly, viruses with a mutation at a noncatalytic residue, D324A, could not be recovered desp

219 Results show that CS uses a noncatalytic residue, M120, located 20 angstrom away fro

220 lutionary interactions between catalytic and noncatalytic residues have been difficult to define and

221 ytic metal-binding residues and two adjacent noncatalytic residues in LAGLIDADG homing endonucleases

222 s in favorable hydrogen bonds with conserved noncatalytic residues in the active site.

223 cale to create motifs of mixed catalytic and noncatalytic residues that identify enzyme activity and

224 ary for catalysis and structurally important noncatalytic residues that together maintain the archite

225 panosoma brucei which contains a degenerate, noncatalytic RNase III domain.

226 In yeast, Rev1 plays a noncatalytic role as an indispensable component of Polze

227 We identify a noncatalytic role for CD45 in regulating tonic, but not

228 We also reveal a critical, noncatalytic role for Exo1, through noncanonical interac

229 omoted COPII assembly in vitro, suggesting a noncatalytic role for Nm23H2.

230 s support a model in which DBT plays a novel noncatalytic role in recruiting additional kinases that

231 Rev1's noncatalytic role in recruiting other DNA polymerases is

232 nt of the Polzeta-Rev1 complex, Rev1 plays a noncatalytic role in the association with DSBs.

233 uggest that cyclin A-cdk2 plays an ancillary noncatalytic role in the ubiquitination of p27 by the SC

234 hese surprising, yet exciting, noncanonical, noncatalytic roles, and highlight how these revelations

235 ace-exposed region of one subunit while in a noncatalytic RT pocket of the other subunit.

236 The core of the cellulosome is a noncatalytic scaffoldin protein, which contains several

237 both the catalytic site and a portion of the noncatalytic, second phosphotyrosine binding site.

238 and Nek7 (303AA), 76% identical, have little noncatalytic sequence but bind to the carboxyl-terminal

239 ivation of transcription by nitroalkenes via noncatalytic sequestration of these ligands, and their g

240 Here we show that the Anopheles gambiae noncatalytic serine protease CLIPA8, an essential factor

241 work of hemolymph serine proteases (HPs) and noncatalytic serine protease homologs (SPHs) and inhibit

242 plex allosteric interactions involving their noncatalytic SH3 and SH2 domains.

243 is accessible by the optimal expression of a noncatalytic signaling component and that altering the e

244 or the i + 2 template position can bind to a noncatalytic site and increase the rate of RNA synthesis

245 demonstrates that L-serine binds to a second noncatalytic site and produces a conformational change i

246 oA levels, the binding of acyl-CoA with this noncatalytic site facilitates homotropic allosteric acti

247 The second, noncatalytic site for L-serine is likely to be the ASB d

248 nds to the active site and a unique proximal noncatalytic site formed by Lys-41, Arg-47, and Asp-48.

249 interact at either the catalytic site or the noncatalytic site interface.

250 nucleotides or alters communication between noncatalytic sites and catalytic sites during ATP hydrol

251 duce a global effect that alters affinity of noncatalytic sites for nucleotides or alters communicati

252 Inhibitors that bind to noncatalytic sites of MMPs and disrupt protease signalin

253 escued by compensatory mutations at adjacent noncatalytic sites that restore an optimal coevolving ne

254 Noncatalytic sites, such as those identified here, can u

255 e subunit were observed at its analogous but noncatalytic sites.

256 In the heterodimeric enzymes, a noncatalytic small subunit (GPPS.SSU) determines the pro

257 CaPPS interacts with the noncatalytic spacer domain of ADAMTS-4 and the cysteine-

258 (1668) segment in the same domain and on the noncatalytic spacer domain of ADAMTS13, suggesting that

259 comprising a catalytic subunit (PriS) and a noncatalytic subunit (PriL).

260 in with one catalytic subunit (Kar3) and one noncatalytic subunit (Vik1).

261 Each complex contains one catalytic and one noncatalytic subunit and exhibits endonuclease activity

262 uring NER requires the presence of a second, noncatalytic subunit called ERCC1.

263 its termed IKKalpha and IKKbeta as well as a noncatalytic subunit called IKKgamma/NEMO.

264 t-translationally by the availability of the noncatalytic subunit collagen Q, and others have shown t

265 alpha4 is an evolutionarily conserved noncatalytic subunit for PP2A-like phosphatases.

266 Polycomb group (PcG) repressor that is a key noncatalytic subunit in the ESC-Enhancer of zeste [E(Z)]

267 h synthase III (SSIII), and isa2, encoding a noncatalytic subunit of heteromeric isoamylase-type star

268 Here we show that alpha4, a noncatalytic subunit of protein phosphatase 2A (PP2A), i

269 In contrast, Psidin functions as the noncatalytic subunit of the N-acetyltransferase complex

270 Capns1 encodes the small noncatalytic subunit that is required for the proteolyti

271 NdmE is proposed to function as a noncatalytic subunit that serves a structural role in th

272 The noncatalytic subunit, Cdc50p, also was reconstituted in

273 re we report the identification of a primase noncatalytic subunit, denoted PriX, from the hyperthermo

274 serine kinases, IKKalpha and IKKbeta, and a noncatalytic subunit, IKKgamma.

275 The IMP also has at least one noncatalytic subunit, Som1p, which is required to cleave

276 which we attribute to the differences in the noncatalytic subunit.

277 Diverged domains are present in the noncatalytic subunits and may be required for substrate

278 through concerted interactions with the two noncatalytic subunits in primer synthesis.

279 The noncatalytic subunits include p270/ARID1A, which is of p

280 B3GAP1 and RAB3GAP2 encode the catalytic and noncatalytic subunits of the hetrodimeric enzyme RAB3GAP

281 Thus, the presence of p261C and the three noncatalytic subunits optimizes the dual enzymatic activ

282 So far, the contribution of the noncatalytic subunits to hPolepsilon function is not wel

283 talytic SET domain subunit, E(Z), plus three noncatalytic subunits, SU(Z)12, ESC, and NURF-55.

284 PRC2 modulation by conserved inputs from its noncatalytic subunits.

285 a-proteobacteria-derived ancestors by adding noncatalytic subunits.

286 The complexes contain seven or more noncatalytic subunits; only one of which, hSNF5/Ini1/BAF

287 L1 activation in the Golgi utilizes the same noncatalytic surface, whereas B4GALT1 uses its active-si

288 ALT1 and ST6GAL1 interact via highly charged noncatalytic surfaces, leaving the active sites exposed

289 c sequence but bind to the carboxyl-terminal noncatalytic tail of Nercc1/Nek9, a NIMA family protein

290 Noncatalytic targeting represents a novel approach to re

291 ogether, our data support the existence of a noncatalytic template-specific NTP binding site in the m

292 oxane, 105 degrees C) or into oxazoles under noncatalytic thermolysis (o-dichlorobenzene, 170 degrees

293 The results demonstrate that noncatalytic thrombospondin-1/cysteine-rich/spacer domai

294 ant stability vs metastability, catalytic vs noncatalytic transduction, pre- vs post-transcriptional

295 Our proteomic studies identified noncatalytic tyrosine and phosphotyrosine sites that can

296 a previously unknown binding site in USP11's noncatalytic ubiquitin-like (UBL) region.

297 As, one enzyme homodimer plays a role of the noncatalytic unit that positions CCA ends of two tRNA(Se

298 between the globular domain of LpoB and the noncatalytic UvrB domain 2 homolog domain of PBP1B and m

299 id-solid growth and vertical facet-selective noncatalytic vapor-solid growth and their parallel integ

300 nsfer was fast enough to afford a reversible noncatalytic wave.