ライフサイエンスコーパス: nonsense-mediated mRNA decay

1 amount of transcript from the mutant allele (nonsense-mediated mRNA decay).

2 odon, and uORFs with strong contexts promote nonsense-mediated mRNA decay.

3 timulation, and abrogates the enhancement of nonsense-mediated mRNA decay.

4 ptional events, translational initiation and nonsense-mediated mRNA decay.

5 idly by a proteasomal pathway rather than by nonsense-mediated mRNA decay.

6 te exon derived from 5S rRNA is coupled with nonsense-mediated mRNA decay.

7 ces a premature termination codon leading to nonsense-mediated mRNA decay.

8 that hERG nonsense mutations are subject to nonsense-mediated mRNA decay.

9 means of an RNA surveillance pathway called nonsense-mediated mRNA decay.

10 odon and, thus, mutant mRNAs were subject to nonsense-mediated mRNA decay.

11 suppressor, and NMD2, which is essential for nonsense-mediated mRNA decay.

12 pt levels, suggesting variable efficiency of nonsense-mediated mRNA decay.

13 All three mutations lead to nonsense-mediated mRNA decay.

14 ture termination codon which is subjected to nonsense-mediated mRNA decay.

15 n mRNA export, cytoplasmic localization, and nonsense-mediated mRNA decay.

16 provides a direct link between splicing and nonsense-mediated mRNA decay.

17 ure stop codon were unstable, as a result of nonsense-mediated mRNA decay.

18 from the mutant allele, as a consequence of nonsense-mediated mRNA decay.

19 delA was also shown to reduce mRNA level via nonsense-mediated mRNA decay.

20 ct and that this interaction is required for nonsense-mediated mRNA decay.

21 Exon E9-long regulates LSD1 levels by Nonsense-Mediated mRNA Decay.

22 ators, altering protein isoforms or inducing nonsense-mediated mRNA decay.

23 ure stop codon readthrough and inhibition of nonsense-mediated mRNA decay.

24 that lead to truncated proteins and promote nonsense-mediated mRNA decay.

25 ease in OTUD7A expression without undergoing nonsense-mediated mRNA decay.

26 TD due to the nonsense mutation, indicating nonsense-mediated mRNA decay.

27 B7 mRNAs harboring r.796c>u were degraded by nonsense-mediated mRNA decay.

28 or penultimate exon, suggesting escape from nonsense-mediated mRNA decay.

29 retention of lipogenic genes, which triggers nonsense-mediated mRNA decay.

30 therefore predicted to result in escape from nonsense-mediated mRNA decay.

31 mulate translation initiation and to inhibit nonsense-mediated mRNA decay.

32 sidered sterile and innocuous as a result of nonsense-mediated mRNA decay.

33 ode a functional protein but was degraded by nonsense-mediated mRNA decay.

34 ing to premature translation termination and nonsense-mediated mRNA decay.

35 mily also resulted in protein truncation and nonsense-mediated mRNA decay.

36 elineated in the initiation factor eIF4G, in Nonsense-mediated mRNA decay 2 protein (NMD2/UPF2), in t

37 ' splice site (A3SS) of SYNGAP1 that induces nonsense-mediated mRNA decay (A3SS-NMD) in mouse and hum

38 tidine-rich region of Upf1p that have normal nonsense-mediated mRNA decay activities but are able to

39 hese results, the role of the Upf complex in nonsense-mediated mRNA decay and nonsense suppression is

40 to the pre-mRNA, which has implications for nonsense-mediated mRNA decay and other mRNA transactions

41 This mutation caused a nonsense-mediated mRNA decay and resulted in the absence

42 a unifying model in which Dbp2p affects both nonsense-mediated mRNA decay and rRNA processing by alte

43 e implies that the mutant message can escape nonsense-mediated mRNA decay and that a truncated RP1 pr

44 families 3 and 4 are predicted to result in nonsense-mediated mRNA decay and the absence of WNT1.

45 In human cells, BlaS inhibits nonsense-mediated mRNA decay and, at subinhibitory conce

46 n occur at low or undetectable levels due to nonsense-mediated mRNA decay, and (iii) the levels of th

47 in a downstream premature termination codon, nonsense-mediated mRNA decay, and abrogation of type XVI

48 o the premature termination codon, countered nonsense-mediated mRNA decay, and allowed protein produc

49 ssenger RNA (mRNA) expression as a result of nonsense-mediated mRNA decay, as well as the production

50 e half-life of TAP-1 mRNA is not mediated by nonsense-mediated mRNA decay because deletions of two ad

51 sted only minimal effects on endonucleolytic nonsense-mediated mRNA decay components, suggesting that

52 gly, the 151insG mutation does not result in nonsense-mediated mRNA decay due to rescue of the transc

53 lternative splicing events, fusion genes and nonsense-mediated mRNA decay events and non-coding RNA s

54 epends on translation and recruitment of the nonsense-mediated mRNA decay factor Upf1 to the ARF1 3'-

55 as most of the remaining transcripts utilize nonsense-mediated mRNA decay factors for Dcp2-mediated t

56 rity of mutations caused loss of mRNA due to nonsense-mediated mRNA decay; however, a recurrent, miss

57 has been completed but is unable to promote nonsense-mediated mRNA decay if it is situated 5' of a t

58 sion, facilitating improved CFTR rescue from nonsense-mediated mRNA decay in a cystic fibrosis human

59 NA decay, suggesting that amlexanox inhibits nonsense-mediated mRNA decay in cells from patients with

60 However, the role of nonsense-mediated mRNA decay in LQT2 mutations has not b

61 al-time PCR, we first evaluated AI caused by nonsense-mediated mRNA decay in patients with frameshift

62 y, the functional association between AS and nonsense-mediated mRNA decay in the context of plant-pat

63 We reveal decreased efficiency of nonsense-mediated mRNA decay in umbilical cord blood, wh

64 from Upf1p and SMG-2, which are required for nonsense-mediated mRNA decay in yeast and Caenorhabditis

65 Both events reduce the nonsense-mediated mRNA-decay-induced degradation of exon

66 Moreover, pateamine A, an inhibitor of nonsense-mediated mRNA decay, inhibits degradation of ab

67 that the degradation of hERG mutant mRNA by nonsense-mediated mRNA decay is an important mechanism i

68 ination codon-containing mRNA transcripts by nonsense-mediated mRNA decay is increasingly recognized

69 These findings provide evidence that nonsense-mediated mRNA decay is related mechanistically

70 an RNA helicase that plays a central role in nonsense-mediated mRNA decay, is conformationally conver

71 human C(87)G-mutated transcripts bypass the nonsense-mediated mRNA decay machinery, suggesting the A

72 us, mutations in other UPF genes involved in nonsense-mediated mRNA decay maintain the M1 virus.

73 CBs in RNA-based regulatory pathways such as nonsense-mediated mRNA decay, mRNA retention, and RNA si

74 ranscript is unstable, presumably because of nonsense-mediated mRNA decay, neither of the aberrant tr

75 potentially targeted for degradation by the nonsense mediated mRNA decay (NMD) surveillance machiner

76 ostly in relation to its cytoplasmic role in nonsense mediated mRNA decay (NMD), here we report high-

77 This decay pathway is often called nonsense- mediated mRNA decay (NMD).

78 s a DNA/RNA helicase with essential roles in nonsense-mediated mRNA decay (NMD) and embryonic develop

79 Despite the ubiquitous nature of nonsense-mediated mRNA decay (NMD) and its demonstrated

80 Nonsense-mediated mRNA decay (NMD) and microRNA (miRNA)-

81 reconstitute Upf1 function in both promoting nonsense-mediated mRNA decay (NMD) and preventing nonsen

82 ion complex core protein Y14 is required for nonsense-mediated mRNA decay (NMD) and promotes translat

83 cally, PTCs induce transcript degradation by nonsense-mediated mRNA decay (NMD) and render such chang

84 mRNA is a naturally occurring mRNA target of nonsense-mediated mRNA decay (NMD) and that the binding

85 Exon 5 inclusion triggers nonsense-mediated mRNA decay (NMD) and unproductive tran

86 Inhibition of protein synthesis and of nonsense-mediated mRNA decay (NMD) by anisomycin shows t

87 The conserved RNA helicase UPF1 coordinates nonsense-mediated mRNA decay (NMD) by engaging with mRNA

88 K) SMG1 monitors the progression of metazoan nonsense-mediated mRNA decay (NMD) by phosphorylating th

89 Johnson et al. (2019) report that inhibiting nonsense-mediated mRNA decay (NMD) contributes to the pa

90 ed intra-axonal protein synthesis coupled to nonsense-mediated mRNA decay (NMD) controls a switch in

91 Nonsense-mediated mRNA decay (NMD) controls the quality

92 Moreover, we found that the nonsense-mediated mRNA decay (NMD) cytoplasmic surveilla

93 Nonsense-mediated mRNA decay (NMD) degrades abnormal and

94 Nonsense-mediated mRNA decay (NMD) degrades EJC-bound mR

95 Disrupting Upf proteins involved in nonsense-mediated mRNA decay (NMD) did not affect Pol pr

96 Nonsense-mediated mRNA decay (NMD) directs rapid degrada

97 Nonsense-mediated mRNA decay (NMD) eliminates transcript

98 UPF3 is a key nonsense-mediated mRNA decay (NMD) factor required for m

99 ng and RNAi, we showed that depletion of the nonsense-mediated mRNA decay (NMD) factor SMG7 or UPF1 s

100 otypes of prt1-1 cells and those lacking the nonsense-mediated mRNA decay (NMD) factor Upf1p led us t

101 requency somatic mutations affecting UPF1, a nonsense-mediated mRNA decay (NMD) factor, in PASC, but

102 Mutations in human nonsense-mediated mRNA decay (NMD) factors are enriched

103 '-to-3' exoribonuclease Xrn1p, and the three nonsense-mediated mRNA decay (NMD) factors, Upf1p, Nmd2p

104 In non-polarized cells, nonsense-mediated mRNA decay (NMD) generally begins duri

105 In mammalian cells, nonsense-mediated mRNA decay (NMD) generally requires th

106 The mechanisms of nonsense-mediated mRNA decay (NMD) have been described i

107 Despite a long appreciation for the role of nonsense-mediated mRNA decay (NMD) in destroying faulty,

108 UPF1 is an RNA helicase that is required for nonsense-mediated mRNA decay (NMD) in eukaryotes, and th

109 Nonsense-mediated mRNA decay (NMD) in mammalian cells is

110 Nonsense-mediated mRNA decay (NMD) in mammalian cells is

111 e assessed the role of factors essential for nonsense-mediated mRNA decay (NMD) in nonsense-mediated

112 terplay of splicing repression by hnRNPC and nonsense-mediated mRNA decay (NMD) in the quality contro

113 Upf3p, which is required for nonsense-mediated mRNA decay (NMD) in yeast, is primaril

114 However, recent studies of nonsense-mediated mRNA decay (NMD) indicate that cap-bin

115 Nonsense-mediated mRNA decay (NMD) is a cellular quality

116 Nonsense-mediated mRNA decay (NMD) is a cellular surveil

117 In mammalian cells, nonsense-mediated mRNA decay (NMD) is a consequence of n

118 Nonsense-mediated mRNA decay (NMD) is a conserved proofr

119 Nonsense-mediated mRNA decay (NMD) is a conserved RNA de

120 Nonsense-mediated mRNA decay (NMD) is a conserved transl

121 Nonsense-mediated mRNA decay (NMD) is a cytoplasmic tran

122 Nonsense-mediated mRNA decay (NMD) is a eukaryotic mRNA

123 Nonsense-mediated mRNA decay (NMD) is a eukaryotic proce

124 Nonsense-mediated mRNA decay (NMD) is a eukaryotic quali

125 Nonsense-mediated mRNA decay (NMD) is a eukaryotic surve

126 Mammalian nonsense-mediated mRNA decay (NMD) is a eukaryotic surve

127 Low CFTR mRNA expression due to nonsense-mediated mRNA decay (NMD) is a major hurdle in

128 Nonsense-mediated mRNA decay (NMD) is a mechanism by whi

129 Nonsense-mediated mRNA decay (NMD) is a network of pathw

130 Nonsense-mediated mRNA decay (NMD) is a quality control

131 Nonsense-mediated mRNA decay (NMD) is a quality control

132 Nonsense-mediated mRNA decay (NMD) is a quality-control

133 mong the various RNA regulatory machineries, nonsense-mediated mRNA decay (NMD) is a stress responsiv

134 Nonsense-mediated mRNA decay (NMD) is a surveillance mec

135 Nonsense-mediated mRNA decay (NMD) is a surveillance pat

136 Nonsense-mediated mRNA decay (NMD) is a surveillance pat

137 Nonsense-mediated mRNA decay (NMD) is a translation-depe

138 Nonsense-mediated mRNA decay (NMD) is a translation-link

139 Nonsense-mediated mRNA decay (NMD) is an essential eukar

140 Nonsense-mediated mRNA decay (NMD) is an evolutionarily

141 emature termination codon (PTC) mutations by nonsense-mediated mRNA decay (NMD) is an important mecha

142 Nonsense-mediated mRNA decay (NMD) is an mRNA degradatio

143 Nonsense-mediated mRNA decay (NMD) is an mRNA surveillan

144 Nonsense-mediated mRNA decay (NMD) is an RNA surveillanc

145 Nonsense-mediated mRNA decay (NMD) is governed by the th

146 Nonsense-mediated mRNA decay (NMD) is of universal biolo

147 Nonsense-mediated mRNA decay (NMD) is the cell's natural

148 Nonsense-mediated mRNA decay (NMD) largely functions to

149 Nonsense-mediated mRNA decay (NMD) limits the production

150 ted to the last intron of target loci due to nonsense-mediated mRNA decay (NMD) making them unsuitabl

151 on of read-through by MoMLV RNase H prevents nonsense-mediated mRNA decay (NMD) of mRNAs.

152 sitide-3 kinase (PI3K) involved in mediating nonsense-mediated mRNA decay (NMD) of transcripts contai

153 Moreover, we found that TANAR could impede nonsense-mediated mRNA decay (NMD) of TWIST1 mRNA by dir

154 This is likely due to nonsense-mediated mRNA decay (NMD) owing to the generati

155 s cerevisiae cells lacking components of the nonsense-mediated mRNA decay (NMD) pathway (Upf1,Upf2, o

156 TC-containing transcripts is mediated by the nonsense-mediated mRNA decay (NMD) pathway and requires

157 We inhibit the nonsense-mediated mRNA decay (NMD) pathway and show that

158 The evolutionarily conserved nonsense-mediated mRNA decay (NMD) pathway degrades aber

159 The nonsense-mediated mRNA decay (NMD) pathway degrades mRNA

160 The nonsense-mediated mRNA decay (NMD) pathway degrades some

161 The nonsense-mediated mRNA decay (NMD) pathway functions by

162 The nonsense-mediated mRNA decay (NMD) pathway functions to

163 The nonsense-mediated mRNA decay (NMD) pathway functions to

164 Components of the nonsense-mediated mRNA decay (NMD) pathway have been imp

165 The nonsense-mediated mRNA decay (NMD) pathway is a highly c

166 The nonsense-mediated mRNA decay (NMD) pathway is an example

167 The nonsense-mediated mRNA decay (NMD) pathway minimizes the

168 The nonsense-mediated mRNA decay (NMD) pathway monitors prem

169 The nonsense-mediated mRNA decay (NMD) pathway monitors tran

170 sociated with multiple mental illnesses, the nonsense-mediated mRNA decay (NMD) pathway presents an u

171 The nonsense-mediated mRNA decay (NMD) pathway rids eukaryot

172 The Nonsense-mediated mRNA decay (NMD) pathway selectively d

173 The nonsense-mediated mRNA decay (NMD) pathway selectively d

174 The nonsense-mediated mRNA decay (NMD) pathway selectively e

175 Inactivation of the yeast nonsense-mediated mRNA decay (NMD) pathway stabilizes no

176 re termination codons (PTCs), activating the nonsense-mediated mRNA decay (NMD) pathway to degrade mo

177 -amino-acid protein that is required for the nonsense-mediated mRNA decay (NMD) pathway, a pathway th

178 escribe advances in our understanding of the nonsense-mediated mRNA decay (NMD) pathway, highlighting

179 The nonsense-mediated mRNA decay (NMD) pathway, present in m

180 productive rearrangements are cleared by the nonsense-mediated mRNA decay (NMD) pathway, the process

181 slated region (UTR) is often degraded by the nonsense-mediated mRNA decay (NMD) pathway.

182 s are recognized and rapidly degraded by the nonsense-mediated mRNA decay (NMD) pathway.

183 of a subset of 3'-UTR splice variants by the nonsense-mediated mRNA decay (NMD) pathway.

184 issue by utilizing the translation-dependent nonsense-mediated mRNA decay (NMD) pathway.

185 g premature termination codons (PTCs) by the nonsense-mediated mRNA decay (NMD) pathway.

186 llelic to NMD2/UPF2, a gene required for the nonsense-mediated mRNA decay (NMD) pathway.

187 t themselves by degrading such mRNAs via the nonsense-mediated mRNA decay (NMD) pathway.

188 tion and decreased mRNA stability due to the nonsense-mediated mRNA decay (NMD) pathway.

189 Robo3.2 is also a predicted target of the nonsense-mediated mRNA decay (NMD) pathway.

190 Nonsense-mediated mRNA decay (NMD) performs two function

191 Nonsense-mediated mRNA decay (NMD) protects cells from t

192 uences in the checkpoint protein p53 and the nonsense-mediated mRNA decay (NMD) protein hUpf1.

193 Nonsense-mediated mRNA decay (NMD) represents a eukaryot

194 Nonsense-mediated mRNA decay (NMD) represents a highly c

195 that APA products include a class of cryptic nonsense-mediated mRNA decay (NMD) substrates with exten

196 ytoplasmic localization of the mRNA, and the nonsense-mediated mRNA decay (NMD) surveillance process.

197 ponse also requires Upf1, a component of the nonsense-mediated mRNA decay (NMD) system.

198 on gene location and resulting efficiency of nonsense-mediated mRNA decay (NMD) to eliminate potentia

199 Here, we show that nonsense-mediated mRNA decay (NMD) underlies clearance o

200 Nonsense-mediated mRNA decay (NMD) was originally concei

201 degraded by the surveillance pathway called nonsense-mediated mRNA decay (NMD) when the selenocystei

202 f2, and Upf3 are the principal regulators of nonsense-mediated mRNA decay (NMD), a cytoplasmic survei

203 nds of transcripts, in some cases triggering nonsense-mediated mRNA decay (NMD), a highly conserved R

204 deposited on spliced mRNAs and functions in nonsense-mediated mRNA decay (NMD), a surveillance mecha

205 These transcripts are apparent targets of nonsense-mediated mRNA decay (NMD), a surveillance mecha

206 eer round of translation (PRT) that precedes nonsense-mediated mRNA decay (NMD), abolishes di-HLA pre

207 Nonsense-mediated mRNA decay (NMD), also called mRNA sur

208 alternative mRNA isoforms are candidates for nonsense-mediated mRNA decay (NMD), an mRNA surveillance

209 ominantly in the cytoplasm and is subject to nonsense-mediated mRNA decay (NMD), and the mature mRNA

210 s selection in vivo is an indirect result of nonsense-mediated mRNA decay (NMD), as conditions that e

211 on of an RNA quality control pathway, termed nonsense-mediated mRNA decay (NMD), by phosphorylating t

212 fth of cases, one isoform appears subject to nonsense-mediated mRNA decay (NMD), supporting the idea

213 Nonsense-mediated mRNA decay (NMD), the loss of mRNAs ca

214 Exemplifying this continuum is nonsense-mediated mRNA decay (NMD), the process wherein

215 ore likely, trigger mRNA degradation through nonsense-mediated mRNA decay (NMD), thus preventing or r

216 ther RNA quality control mechanisms, such as nonsense-mediated mRNA decay (NMD), which degrades both

217 Nonsense-mediated mRNA decay (NMD), which degrades trans

218 Here, we review nonsense-mediated mRNA decay (NMD), which is the best-ch

219 ufen 1 (STAU1)-mediated mRNA decay (SMD) and nonsense-mediated mRNA decay (NMD), which we show here a

220 neuronal cells focused on mRNAs targeted for nonsense-mediated mRNA decay (NMD), which we showed are

221 Transcriptomes of nonsense-mediated mRNA decay (NMD)-impaired and heat-str

222 Upf1 allows disassembly of mRNPs undergoing nonsense-mediated mRNA decay (NMD).

223 get them for destruction, a process known as nonsense-mediated mRNA decay (NMD).

224 mRNAs that contain them, a phenomenon called nonsense-mediated mRNA decay (NMD).

225 CPA1 expression is also controlled by nonsense-mediated mRNA decay (NMD).

226 (PTC) and are therefore potential targets of nonsense-mediated mRNA decay (NMD).

227 ript degradation in eukaryotic cells through nonsense-mediated mRNA decay (NMD).

228 ly and rapidly degraded, a phenomenon termed nonsense-mediated mRNA decay (NMD).

229 virus (CaMV) can function as a suppressor of nonsense-mediated mRNA decay (NMD).

230 hypothesis that these mRNAs were targets of nonsense-mediated mRNA decay (NMD).

231 ex recruits Upf3 and Upf2, which function in nonsense-mediated mRNA decay (NMD).

232 codons (PTCs) are selectively eliminated by nonsense-mediated mRNA decay (NMD).

233 s elegans SMG-1, a protein that functions in nonsense-mediated mRNA decay (NMD).

234 he mutant allele were found to be subject to nonsense-mediated mRNA decay (NMD).

235 eukaryotic cells through a pathway known as nonsense-mediated mRNA decay (NMD).

236 to accelerated mRNA decay is referred to as nonsense-mediated mRNA decay (NMD).

237 les in regulation of DNA damage response and nonsense-mediated mRNA decay (NMD).

238 which frequently acquire mutations inducing nonsense-mediated mRNA decay (NMD).

239 with proteins involved in mRNA decapping and nonsense-mediated mRNA decay (NMD).

240 ns, especially when they are not targeted by nonsense-mediated mRNA decay (NMD).

241 slation of a full-length protein and trigger nonsense-mediated mRNA decay (NMD).

242 RNA silencing, defense against viral RNA and nonsense-mediated mRNA decay (NMD).

243 n codons (PTCs) are rapidly degraded through nonsense-mediated mRNA decay (NMD).

244 ery, and the terminating ribosome to promote nonsense-mediated mRNA decay (NMD).

245 corresponding transcript for degradation by nonsense-mediated mRNA decay (NMD).

246 In eukaryotes, the phenomenon is known as nonsense-mediated mRNA decay (NMD).

247 on (PTC) predicted to elicit degradation via nonsense-mediated mRNA decay (NMD).

248 s, were associated with poor translation and nonsense-mediated mRNA decay (NMD).

249 we analyzed other gene products required for nonsense-mediated mRNA decay (NMD).

250 all eukaryotes tested, a phenomenon termed "nonsense-mediated mRNA decay" (NMD) or "mRNA surveillanc

251 wild-type counterparts, a phenomenon termed "nonsense-mediated mRNA decay" (NMD) or "mRNA surveillanc

252 s) are rapidly degraded by a process termed "nonsense-mediated mRNA decay" (NMD).

253 rapidly in eukaryotes, a phenomenon termed 'nonsense-mediated mRNA decay' (NMD).

254 verview of three quality control mechanisms--nonsense-mediated mRNA decay, nonstop mRNA decay, and no

255 Transition in the extent of nonsense-mediated mRNA decay occurred within a 48-nt seg

256 ive H3K36me3-regulated AS event leading to a nonsense-mediated mRNA decay of BARD1.

257 frameshift mutations to exon 11 resulted in nonsense-mediated mRNA decay of full-length, but not the

258 c.818_821dup/p.(Ser275Asnfs*13) resulting in nonsense-mediated mRNA decay of the CACNA2D1 transcripts

259 Exon 8 inclusion causes nonsense-mediated mRNA decay of Trim46 transcripts.

260 anslation and turnover and the dependence of nonsense-mediated mRNA decay on the activity of the UPF1

261 d cells is not related to the suppression of nonsense-mediated mRNA decay or to the inhibition of TNF

262 mutant mRNA was either degraded partially by nonsense-mediated mRNA decay or translated to a stable,

263 significant mRNA destabilization through the nonsense mediated mRNA decay pathway (NMD), and genetic

264 The human nonsense-mediated mRNA decay pathway (NMD) performs qual

265 nnot be fully translated are degraded by the nonsense-mediated mRNA decay pathway (NMD).

266 The nonsense-mediated mRNA decay pathway and cell type-depen

267 The nonsense-mediated mRNA decay pathway functions to degrad

268 The nonsense-mediated mRNA decay pathway is an example of an

269 We show that upf3a (a member of the nonsense-mediated mRNA decay pathway) and components of

270 lso been linked to mRNA decay, including the nonsense-mediated mRNA decay pathway, and to nucleocytop

271 ic transport of spliced mRNA, as well as the nonsense-mediated mRNA decay pathway, are discussed.

272 One clear example of this linkage is the nonsense-mediated mRNA decay pathway, in which nonsense

273 In one model, Naxos plakoglobin bypassed the nonsense-mediated mRNA decay pathway, resulting in norma

274 % of identified variants are targeted to the nonsense-mediated mRNA decay pathway.

275 this mutation did not have any affect on the nonsense-mediated mRNA decay pathway.

276 to conclude that Dbp2p also functions in the nonsense-mediated mRNA decay pathway.

277 PF3 genes encode trans-acting factors of the nonsense-mediated mRNA decay pathway.

278 ct with Upf1p, an essential component of the nonsense-mediated mRNA decay pathway.

279 pendent, interacting components of the yeast nonsense-mediated mRNA decay pathway.

280 stand the mechanism of Upf1p function in the nonsense-mediated mRNA decay pathway.

281 PF1, a gene whose product is involved in the nonsense-mediated mRNA decay pathway.

282 harboring the mof4-1 allele inactivated the nonsense-mediated mRNA decay pathway.

283 the GCN4 transcript was not degraded by the nonsense-mediated mRNA decay pathway.

284 abilizes some tagged mRNAs by activating the nonsense-mediated mRNA decay pathway.

285 tly spliced pre-mRNA population elicited the nonsense-mediated mRNA decay pathway.

286 rs Y14 and Magoh, two known mediators of the nonsense-mediated mRNA decay pathway.

287 mination codon, destabilizing it through the nonsense-mediated mRNA decay pathway.

288 lifecycle from splicing to surveillance via nonsense-mediated mRNA decay pathway.

289 ns cause a decrease in mutant mRNA levels by nonsense-mediated mRNA decay rather than production of t

290 y tune gene expression through coupling with nonsense-mediated mRNA decay, rather than encode differe

291 te of decay of nonsense mutant mRNAs, called nonsense-mediated mRNA decay, requires three proteins, U

292 utations that are expected to be degraded by nonsense-mediated mRNA decay, resulting in haploinsuffic

293 inding motifs direct the decapping enzyme to nonsense-mediated mRNA decay substrates, a single Edc3-b

294 on of UPF-1, an RNA helicase associated with nonsense-mediated mRNA decay, suggesting that amlexanox

295 codon, yet the K8beta mRNA is insensitive to nonsense-mediated mRNA decay, suggesting that the trunca

296 Although Y567X caused nonsense mediated mRNA decay, the amount of TRPV4 protei

297 le deletions of UPF1, NMD2, and UPF3 inhibit nonsense-mediated mRNA decay to the same extent; and an

298 In addition, a yeast strain deficient in nonsense-mediated mRNA decay was generated to prevent ra

299 a premature termination codon that triggers nonsense-mediated mRNA decay when included in the transc

300 h non-canonical EJCs are capable of inducing nonsense-mediated mRNA decay when present downstream of