ライフサイエンスコーパス: nonstandard

1 derivative of Ahppa, and two residues of the nonstandard 2,3-dehydro-2-aminobutanoic acid (Dab).

2 A nonstandard abbreviation for milliliter (not mL) was use

3 ting structural features of teixobactin with nonstandard amino acid (three d-amino acids and l-allo-e

4 ins that incorporate selenocysteine (Sec), a nonstandard amino acid encoded by UGA, normally a stop c

5 This bacterium can biosynthesize a nonstandard amino acid from basic carbon sources and inc

6 The N-linked sites are associated with nonstandard amino acid motifs as a result of glycosylati

7 The incorporation of the nonstandard amino acid para-nitro-L-phenylalanine (pN-Ph

8 oparticles, facilitated by incorporating the nonstandard amino acid propargyloxy-phenylalanine, incre

9 s proteomics probes that enable liganding of nonstandard amino acid residues and application in lipid

10 codon that is recognized as a codon for the nonstandard amino acid selenocysteine (Sec).

11 -iodo-Tyr(B26)-lispro thus illustrates how a nonstandard amino acid substitution can mitigate the unf

12 Expansion of the genetic code with nonstandard amino acids (nsAAs) has enabled biosynthesis

13 These nonstandard amino acids are beneficial as they facilitat

14 incorporation has greatly expanded access to nonstandard amino acids by expanding the scope of the tr

15 borious process because many NRPs consist of nonstandard amino acids that are assembled by nonribosom

16 ted improved properties for incorporation of nonstandard amino acids that expand the chemical diversi

17 ole-genome recoding has been shown to enable nonstandard amino acids, biocontainment and viral resist

18 nthesized nonribosomally, they often contain nonstandard amino acids, thus increasing the complexity

19 idue at position 32 in the polypeptide, with nonstandard amino acids.

20 aracterization and lack of transparency, (2) nonstandard and unverified disease labels, and (3) inabi

21 easured in multiple views with zoom mode and nonstandard angulation to optimize its visualization.

22 n stroke and support the need for studies of nonstandard antiplatelet therapies for patients expressi

23 d consortia (CHARGE, GBPgen, and ICBP) and a nonstandard approach (age stratification and metaregress

24 Multiple nonstandard as well as standard amino acids were toxic t

25 eudohyphal differentiation under a number of nonstandard assay conditions including altered temperatu

26 Among oligonucleotides composed entirely of nonstandard backbones, only phosphorothioate DNA support

27 originally encoded by bases attached to the nonstandard backbones.

28 ) pairs with Watson-Crick geometry to both a nonstandard base (2-amino-8-imidazo-[1,2a]-1,3,5-triazin

29 re extra DNA building blocks that form tight nonstandard base pairs without cross-binding to natural

30 flect, in part, the preferred use of certain nonstandard base pairs, e.g., U-G.

31 The standard OLA was optimized by using nonstandard bases in oligonucleotides to allow promiscuo

32 on stem-loops with different combinations of nonstandard bases were performed.

33 if, GAGGXX, that results in NADPH adopting a nonstandard binding mode with the nicotinamide and ribos

34 a meta-analysis of 8 large studies that used nonstandard BMI categories and were published between 19

35 s of BMI and the risk of death sometimes use nonstandard BMI categories that vary across studies.

36 Studies that used nonstandard BMI categories, that were limited to childre

37 os varied the AI recommendation (standard or nonstandard care) and the physician's decision (to accep

38 However, when an AI system recommends nonstandard care, there is no similar shielding effect o

39 Studies were excluded that used nonstandard categories or that were limited to adolescen

40 robes of the B24 pocket and suggest that the nonstandard Cha side chain may have therapeutic utility.

41 y Imp1p, signal peptides having standard and nonstandard cleavage sites can be processed by Imp1p, an

42 ned on a genome-wide scale in yeast grown in nonstandard conditions.

43 ded when these components are implemented in nonstandard configurations outside of manufacturer speci

44 Moreover, the structure revealed a novel, nonstandard conformation of FVIIa active site in the reg

45 y to undergo transitions that "trap" them in nonstandard conformational substates.

46 Nonstandard conformations yielded less favorable PEs by

47 dard matrix to frequencies appropriate for a nonstandard context.

48 at this structural information is encoded in nonstandard correlation functions.

49 ce relative to that in health care settings, nonstandard counseling following receipt of test results

50 derations include accounting for covariates, nonstandard crosses, missing genotypes, genotyping error

51 abase search and error-modeling methods with nonstandard data sets and custom sequence databases.

52 instead of to Jbeta cleavages, resulting in nonstandard Dbeta1-Dbeta2-Jbeta2 joints.

53 d definitions and address the confusion that nonstandard definitions of widely used end point terms f

54 antly lower in animals that had been fed the nonstandard diets.

55 "Twisted" amides containing nonstandard dihedral angles are typically hypersensitive

56 Using the previously described nonstandard DNA base pair constructed from isoguanine an

57 The i-motif is a class of nonstandard DNA structure with potential biological impl

58 modified bases and to replicate beyond such nonstandard DNA structures in a process known as transle

59 tor length K ~ 100 elements) or has required nonstandard DNN models and retraining, hindering widespr

60 es for heart transplant recipients increase, nonstandard donor hearts are increasingly being used for

61 acy, enable continuous QTc surveillance from nonstandard ECG vectors, and identify clinically meaning

62 elations between fourth-order clustering and nonstandard epidemic dynamics.

63 models, current quantitative descriptions of nonstandard epidemic profiles are either abstract, pheno

64 Based on this single animal study using nonstandard evaluation of retinopathy, clinical trials a

65 ntation, and ultimately mitigate reliance on nonstandard exceptions.

66 ors reported by Das and colleagues reflected nonstandard experiment and data processing choices, and

67 erformance of ELISAs often varies because of nonstandard experimental procedures as well as inadequat

68 we show how it can be used to both represent nonstandard gene structures (in the form of trans-splice

69 In particular, nonstandard genetic codes are characteristic of several

70 er general design principles for engineering nonstandard genetic codes for enhanced and diminished ev

71 tricities, such as scrambled coding regions, nonstandard genetic codes, and convoluted modes of postt

72 an the commonly used FastNGSadmix when using nonstandard genomic material.

73 estigators have studied how proteins enforce nonstandard geometries on metal centers to assess the qu

74 solute assay of special nuclear materials in nonstandard geometry samples with an unknown matrix, whi

75 d an unknown nuclear material mixture with a nonstandard geometry, compound matrices, and a wide vari

76 Under the nonstandard GeparSixto polychemotherapy regimen, patient

77 ffects of perturbations, which often exhibit nonstandard growth curves.

78 structure of alpha CTD, alpha CTD contains a nonstandard helix followed by four alpha-helices.

79 on, human leukocyte antigen mismatch, use of nonstandard immunosuppression therapy, deceased donor, p

80 human behavior during epidemics that exhibit nonstandard incidence patterns.

81 ding frame that is initiated by one of three nonstandard initiation codons, and the sequence coding t

82 Nonstandard interventions that led to a detectable impro

83 99 kcal/mol on seven stacked pairs involving nonstandard isocytidine-isoguanosine pairs.

84 and signal joints, they can participate in a nonstandard joining process, forming hybrid and open/shu

85 ement pipet with reconfigurable channels for nonstandard liquid handling applications.

86 advancement of custom analytical tools with nonstandard liquid handling requirements and provides an

87 ch can yield biased, error-prone results; 2) nonstandard lists of microtextures; and 3) relatively la

88 depletion (STED) nanoscopy, applying a novel nonstandard live cell staining protocol.

89 We also present examples of nonstandard marine metazoan model species that have made

90 We discuss how this provides a step toward a nonstandard method of inferring (deciphering) the motiva

91 Using nonstandard methods, we found that all tested Helcococcu

92 using the standard Centiloid pipeline and a nonstandard MRI-based pipeline (native space, cerebellar

93 Restraining the hinge by nonstandard mutagenesis preserves native folding but blo

94 Here, we employ nonstandard mutagenesis to design an insulin analog with

95 e that this trade-off may be circumvented by nonstandard mutagenesis.

96 g is investigated by photo-cross-linking and nonstandard mutagenesis.

97 Improved constraints on nonstandard neutrino interactions with quarks are derive

98 a detectable VL were as follows: exposure to nonstandard nonnucleoside reverse-transcriptase inhibito

99 within the framework of our newly developed nonstandard nucleation theory, which allows prediction o

100 nduce pentameric assembly of DNA bearing the nonstandard nucleobase iso-guanine.

101 uplexes showing this to be the case with two nonstandard nucleobases (Z, 6-amino-5-nitro-2(1H)-pyrido

102 bp exchanged region) were replaced with the nonstandard nucleosides 2'-deoxyisoguanosine (iG) and 2'

103 des an effective platform for exploration of nonstandard nucleosome subtypes.

104 te sequences into sequences that incorporate nonstandard nucleotides (Z and P).

105 ompatibility of the Hel308 motor enzyme with nonstandard nucleotides by tracking the translocation of

106 The most common nonstandard nucleotides found in genomic DNA are ribonuc

107 Modified DNA aptamers containing such nonstandard nucleotides have been developed for >20 diff

108 purpose, PCR workflows are needed to replace nonstandard nucleotides in (for example) a 6-letter DNA

109 the intrinsic orthogonality of standard and nonstandard nucleotides often demand polymerases that vi

110 ver, other applications require standard and nonstandard nucleotides to communicate with each other.

111 ify GACTZP DNA with little loss of the AEGIS nonstandard nucleotides, and (iii) technologies to deep

112 nability to directly sequence DNA containing nonstandard nucleotides.

113 e not been tested in predictive trials or on nonstandard nucleotides.

114 ce and the right hand in the left hemispace (nonstandard oculomotor-somatomotor mapping).

115 We demonstrate that the nonstandard oligonucleotides are substrates for the RecA

116 (the standard G, A, C, and T, and the AEGIS nonstandard P and Z nucleotides, the last having a nitro

117 ions, the orthogonal pairing of standard and nonstandard pairs offers a key advantage.

118 t augmented (and sometimes counterintuitive) nonstandard personalized medicine strategies may lead to

119 ods allow systematic study and evaluation of nonstandard personalized medicine strategies.

120 This results in a nonstandard positioning of the peptide N terminus, which

121 Still, nonstandard positions are used in clinical practice (eg,

122 challenge also identified several potential nonstandard predictors of disease progression including

123 orbidity indices were more likely to receive nonstandard primary tumor therapy, to not receive axilla

124 Inconsistencies and errors resulting from nonstandard processes, together with redundancies, rewor

125 ackbone is obtained through the synthesis of nonstandard protein and DNA analogs.

126 Toxic Abeta oligomers contain a nonstandard protein structure, termed alpha-sheet, and d

127 Ten trials (22%) compared 2 types of nonstandard PT interventions; 26 (57%), nonstandard PT v

128 A meta-analysis compared outcomes of nonstandard PT vs standard PT and standard PT vs no inte

129 [SMD], -1.09; 95% CI, -2.50 to 0.33) or for nonstandard PT vs standard PT in measures of gait (SMD,

130 s of nonstandard PT interventions; 26 (57%), nonstandard PT vs standard PT; and 10 (22%), PT vs no in

131 netic resonance spectroscopy are examples of nonstandard radiographic techniques, which have expanded

132 accuracy and quality assurance for use with nonstandard radionuclides, especially with longer half-l

133 vestigate the underlying mechanisms of these nonstandard recombination events, we took advantage of r

134 CS) with a modern dose-dense dose-escalated (nonstandard) regimen including both an anthracycline and

135 n (P = .021) were associated with the use of nonstandard regimens in univariate analyses.

136 Receipt of nonstandard regimens was examined according to clinical

137 he CALGB-49907 and ELDA trials, and modified nonstandard regimens, for the lack of strong evidence in

138 (P < .0001) were associated with receipt of nonstandard regimens.

139 d to identify factors associated with use of nonstandard regimens.

140 n the second disulfide loop with standard or nonstandard residues and assessing their activity on alp

141 ng optimal sample preparation conditions for nonstandard samples: (i) DMF-DMA at 300 degrees C for 1-

142 nly on corticosteroids, followed by multiple nonstandard second-line options.

143 f different amyloid proteins adopt a common, nonstandard secondary structure, called alpha-sheet.

144 chniques, that these Abeta oligomers adopt a nonstandard secondary structure, termed "alpha-sheet." T

145 as have ITAM-like signaling mechanisms using nonstandard sequence motifs.

146 The nonstandard side chains project into solvent at the edge

147 b and superior to tape strip, especially for nonstandard skin surfaces.

148 d a significant improvement in accuracy with nonstandard, soft-copy review settings (P = .03, one-tai

149 Nonstandard spectral changes occur on CYP51 reduction (u

150 namic model based on published values of the nonstandard state reduction potentials at pH 7.0 (E'H) s

151 A nonstandard strand-specific analysis of the data allowed

152 Nonstandard strategies also consider minor subclones, dy

153 ixture of standard cloverleaf structures and nonstandard structures containing TV replacement loops a

154 active chiral analogue of insulin containing nonstandard substitution allo-Ile(A2) is described at 2.

155 xes show us new twists, such as the use of a nonstandard sushi-type alpha receptors for IL-2 and IL-1

156 veal unexpected problems that can occur with nonstandard synthesis, deprotection, or purification str

157 h relatively short mean durations and use of nonstandard tardive dyskinesia definitions.

158 y relationships were probed via standard and nonstandard techniques (alanine scanning and hydrophile

159 On implantation, some variants demand nonstandard techniques of reconstruction or implantation

160 etrieval was performed, as defined by use of nonstandard techniques, filter fracture, filter tip inco

161 Tier 1 guidance to investigate the impact of nonstandard testing conditions on broth microdilution te

162 Recipients of nonstandard, that is, expanded criteria donor, kidneys a

163 urrent literature regarding the standard and nonstandard therapies for children with autism is review

164 were considered individually, and all other nonstandard therapies were analyzed collectively.

165 ponded, compared to only 9% who responded to nonstandard therapy (p < 0.001).

166 nhances the recombination of substrates with nonstandard topologies which may be more relevant to the

167 mRNA predicted a noncanonical TATA box with nonstandard transcription start site spacing.

168 d RNA editing may be a mechanism for marking nonstandard transcripts, not destined for translation.

169 h antidepressants have prompts addition of a nonstandard treatment (augmentation therapy).

170 Legal scholars argue that following such nonstandard treatment recommendations will increase liab

171 children (80.0%) were recommended to receive nonstandard treatment regimens for potential drug therap

172 re can be generally described as two type IV nonstandard turns around Arg(1)*, Pro(2), Lys(3), and Pr

173 We show that nonstandard V(D)J recombination products (hybrid joints)

174 <9 months, and those using animal models or nonstandard vaccines or administration routes.

175 e respects, it resembles other vernacular or nonstandard varieties, like Cockney or Appalachian Engli

176 nt; 112 of 1,207 segments were reassigned to nonstandard vascular territories.

177 Nonstandard ventilatory support of patients with CDH has

178 ers (baseline and next round), implants, and nonstandard views.

179 in spelling errors, abbreviations, and other nonstandard ways of representing clinical concepts.

180 t with CRISPR/Cas9-generated null mutants in nonstandard wild accessions.

181 rk evening, night, or rotating shifts (i.e. "nonstandard" work hours).