ライフサイエンスコーパス: nontoxic

1 ce to enzymatic degradation, while remaining nontoxic.

2 r of magnitude more effective than CLR01 and nontoxic.

3 the Orb2 protein can stabilize memory and be nontoxic.

4 complex 6 is also remarkably photostable and nontoxic.

5 stabilized low molecular weight species are nontoxic.

6 operon in Y. pseudotuberculosis rendered it nontoxic.

7 minal beta-amyloid fragment is monomeric and nontoxic.

8 embryos/larvae while selenate and SeNPs were nontoxic.

9 em 100 % CEES was transformed selectively to nontoxic 2-chloroethyl ethyl sulfoxide and vinyl ethyl s

10 IV administration of a nontoxic 5-mL dose of iohexol.

11 ion through stabilization of small (dimeric) nontoxic Abeta conformers.

12 eta38 or Abeta40) and other longer peptides (nontoxic Abeta42 G33A substitution or Abeta43) did not a

13 urotoxicity by promoting the accumulation of nontoxic aggregates.

14 forms of polyQ proteins and direct them into nontoxic aggregates.

15 Taken together, 10-Cl-BBQ is an effective, nontoxic AhR ligand for the intervention of immune-media

16 ducted a chemical library screen to identify nontoxic AhR ligands with anti-cancer effects and discov

17 The reaction is catalyzed by nontoxic, air-stable, and inexpensive Cp*Co(CO)I(2) cata

18 w that the HaloTag pulse-chase approach is a nontoxic alternative to inhibition of protein synthesis

19 The replacement of lead with nontoxic alternatives such as tin has been demonstrated

20 The recent introduction of nontoxic ammunition has made impossible the characteriza

21 ristatin E (MMAE) are partially activated by nontoxic amounts of platinum salts.

22 n favor of the formation of larger insoluble nontoxic amyloid fibrils, there by counteracting Abeta-m

23 literature, and (3) the redox products were nontoxic and appropriate for medical applications.

24 lly attractive alternative, because of their nontoxic and biodegradable nature.

25 rsal Heparin Reversal Agent (UHRA), which is nontoxic and can neutralize the anticoagulant activity o

26 etate as the nitrogen source, and aldehydes (nontoxic and cheap alternatives of amines) for the first

27 y gained increasing attention as potentially nontoxic and defect-tolerant solar absorbers.

28 ical inhibition of Mnks therefore provides a nontoxic and effective strategy for cancer therapy.

29 An ST vaccine should be nontoxic and elicit an immune response that neutralizes

30 well-defined materials are synthesized from nontoxic and environment-friendly CDs, which possess a u

31 Oxoammonium salts are metal-free, nontoxic and environmentally friendly oxidants.

32 itation for crosslinking and thus provides a nontoxic and facile approach to encapsulate cells and pr

33 tein is expressed in Escherichia coli and is nontoxic and immunogenic in mice, rabbits, and humans.

34 perational simplicity and the application of nontoxic and inexpensive CeCl3.7 H2O as precatalyst.

35 Bi, as a nontoxic and inexpensive diamagnetic heavy metal, has be

36 In this protocol, the nontoxic and inexpensive Fe(NO3)3.9H2O plays a dual role

37 es an experimental in vitro model system for nontoxic and low-dose coexposures of human mammary carci

38 trum homodimeric tobramycin adjuvant that is nontoxic and more potent than the gold standard permeabi

39 ic activity and have hyaluronidase, which is nontoxic and nonproteolytic but promotes diffusion of to

40 economy, (v) a metal-free process, and (vi) nontoxic and reusable organocatalysts.

41 Besides being nontoxic and specific, desirable labelling probes should

42 We report here a series of nontoxic and stable bismuth-based perovskite nanocrystal

43 animals, labeling of the target cells with a nontoxic and stable contrast agent is a prerequisite.

44 e without host-specific promoters, achieving nontoxic and tuneable gene expression in diverse Gram-po

45 bonate has been put forth as an inexpensive, nontoxic, and "green" potential methylating reagent.

46 ch can also benefit from having sustainable, nontoxic, and degradable materials.

47 ally manipulate, exhibit exquisite SARs, are nontoxic, and elicit improved and qualitatively differen

48 g nanocrystals described here offer a cheap, nontoxic, and environmentally friendly alternative to in

49 eplacing such a precious metal with a cheap, nontoxic, and environmentally friendly substitute such a

50 and on-board power supplies that are benign, nontoxic, and even biodegradable.

51 st abundant element in the earth's crust, is nontoxic, and is a robust material offering high efficie

52 ontinued our effort to generate new, potent, nontoxic, and multiply effective inhibitors of the three

53 eveloped inhibitors that are cell permeable, nontoxic, and selectively bind to the inactive IRF5 mono

54 studied concentrations (1 nM-5 microM), are nontoxic, and showed efficacy in reducing the rate of tu

55 Our data introduce APP-103 as a novel, nontoxic, and site-activating therapeutic approach that

56 tems as they are water-soluble, photostable, nontoxic, and their surface chemistry can be easily modi

57 gnesium or aluminum), combined with a cheap, nontoxic, and water-soluble proton source (dimethylurea)

58 on of neomycin, an inexpensive and vaginally nontoxic antibiotic, is sufficient to pull CD8 T cells t

59 Myo-Inositoltrispyrophosphate (ITPP), a nontoxic, antihypoxic compound, has recently shown signi

60 istant (MDR) Enterobacterales on the rise, a nontoxic antimicrobial agent with a unique mechanism of

61 mmune restriction factors is a promising and nontoxic approach for improving LV-mediated gene therapy

62 rations than aspirin, and thus may provide a nontoxic approach to harnessing aspirin's anticancer act

63 en found to contain a high proportion of the nontoxic arsenic compound arsenobetaine (AB), but data g

64 gation in cells, leading to the formation of nontoxic aSyn species.

65 on black (CB) nanoparticles were found to be nontoxic at all concentrations, while hydrophobic (annea

66 Cer-SiR is nontoxic at concentrations as high as 2 muM and does not

67 macokinetic (PK) profile than sTRAIL and was nontoxic at doses ranging from 32 fmol/kg to 3.2 pmol/kg

68 Monodisperse multifunctional and nontoxic Au@MnO Janus particles with different sizes and

69 To meet this demand, we synthesized nontoxic, azido-functionalized ceramides allowing for bi

70 However, such strategies are likely to be nontoxic because deploying toxins against related indivi

71 ated cytotoxicity peaks, en route to forming nontoxic beta-sheet fibrils.

72 e double-perovskite structure to incorporate nontoxic Bi(3+) into the perovskite lattice in Cs2AgBiBr

73 nanoparticles and it is envisaged that these nontoxic bioactive nanostructures can be used as food pa

74 to develop a highly stable, NIR fluorescent, nontoxic, biocompatible, and highly excreted compound th

75 roperties, CNM is strong and stiff, but also nontoxic, biodegradable, and sustainable with a very lar

76 efforts to replace these with biodegradable, nontoxic, biologically synthesized alternatives.

77 tosan is a biodegradable, antibacterial, and nontoxic biopolymer used in a wide range of applications

78 ts that can be accessed from inexpensive and nontoxic bismuth salts.

79 eceptor antagonists are still susceptible to nontoxic BRD9 inhibitors, making them a promising altern

80 rough one-step rapid polycondensation of two nontoxic building blocks: L-cystine ester and versatile

81 Both are nontoxic by a variety of measures and display good stabi

82 Furthermore, we show that 7,11-HD is nontoxic, can mask underlying substrates (for example, y

83 Here, an inexpensive and nontoxic carbon nitride/nickel phosphide (CN(x)|Ni(2)P)

84 ducts of the polynitro-CNT decomposition are nontoxic: carbon dioxide and molecular nitrogen.

85 The method employs inexpensive and nontoxic catalyst (iron(II) bromide) and reductant (zinc

86 l synthesis of hinduchelins A-D, a family of nontoxic catechol derivatives from Streptoalloteichus hi

87 Finally, an optimized nontoxic cationic NP contrast agent was evaluated in an

88 In this study, we developed a nontoxic cell-permeable ORF45-derived peptide from the R

89 We designed a nontoxic cell-permeable peptide derived from ORF45, TAT-

90 se a positive hit needs simultaneously to be nontoxic, cell permeable, and inhibiting precursor autop

91 profile similar to plant safeners, which are nontoxic chemicals stimulating detoxification pathways i

92 ural constructs treated with 34 toxic and 26 nontoxic chemicals.

93 A nontoxic chromatographic matrix, with low cost and high

94 A reliable nontoxic CNI-free regimen may ultimately require the com

95 stems, both IF-MoS2 and INT-WS2 NPs remained nontoxic compared to equivalent concentrations (up to 10

96 These nontoxic composites can be three-dimensionally printed o

97 iation (lambda > 400 nm), in contrast to the nontoxic compound 7, which is in accord with the results

98 etylates processed McC, converting it into a nontoxic compound.

99 ng doxorubicin antiproliferative activity at nontoxic concentration.

100 mpaired differentiation, whereas addition of nontoxic concentrations of Cu(+)-enhanced MTF1 expressio

101 TAT5 phosphorylation, which was abrogated by nontoxic concentrations of the JAK1/2 inhibitor ruxoliti

102 lcicytes allow for fast calcium flow at low, nontoxic concentrations through undifferentiated cells b

103 e reduction in a colon cancer mouse model at nontoxic concentrations.

104 ty focused ultrasound (LOFU), a noninvasive, nontoxic, conformal therapy, to deliver acoustic stress

105 adsorption and reduction of toxic Cr(VI) to nontoxic Cr(III).

106 eads were functionalized with citric acid as nontoxic cross linker and activated by 1-ethyl-3-(3-dime

107 Laminarin (LAM-OH) is a highly abundant, nontoxic, degradable polysaccharide found in marine orga

108 ormation of chlorobenzene via benzene to the nontoxic degradation products, CO2 and CH4.

109 tes BMMSCs and that restoring H2S levels via nontoxic donors may provide treatments for diseases such

110 paper demonstrates that an application of a nontoxic dosage of GHz ultrasonic waves [Formula: see te

111 the external environment, MDMA at a moderate nontoxic dose (9 mg/kg or ~1/5 of LD50 in rats) can caus

112 s.c. B16F10 melanoma model, we found that a nontoxic dose of IL-2 immunocytokine synergized with tum

113 iravir demonstrate that an antiviral drug at nontoxic doses exhibits a marked protective effect again

114 ts and demonstrate that clinically relevant, nontoxic doses of 5-azacytidine can restore erythropoiet

115 n of the spinal cord, systemic injections of nontoxic doses of amphotericin B and another activator,

116 Nontoxic doses of brefeldin A also prevented the dorsal

117 We show that nontoxic doses of l-buthionine sulfoximine increase the

118 Elevated, nontoxic doses of manganese (Mn) protect against Shiga t

119 Supplementation with nontoxic doses of micronutrient selenium has been shown

120 At nontoxic doses, 1 promoted osteogenic differentiation.

121 At nontoxic doses, atorvastatin and mevastatin were unable

122 as when administered at supraphysiologic but nontoxic doses.

123 so, therapy with stable, less-expensive, and nontoxic EGFR peptide mimics will block EGFR signaling a

124 In addition to being made of abundant and nontoxic elements, we show that this material behaves as

125 , water consumption, pesticide toxicity, and nontoxic emissions linked to fertilizer use.

126 Because it is a natural, nontoxic, environmentally benign cobalt complex, cobalam

127 The major product was nontoxic ethane (94% selectivity).

128 logenation at contaminated sites can produce nontoxic ethene but often stops at toxic cis-1,2-dichlor

129 ced dechlorination of chlorinated ethenes to nontoxic ethene was observed long after the expected nZV

130 We used nontoxic eutectic gallium-based alloys as a reaction sol

131 g, toxic repeat expansions, but not shorter, nontoxic expansions.

132 there is a need to achieve efficient, safe, nontoxic, fast, and economical processing of clinically

133 d on the cell membrane by treatment with the nontoxic FDA approved drug, trimethoprim.

134 egation reaction could be modulated to favor nontoxic fibrils over toxic fibrils.

135 Bright, photostable, and nontoxic fluorescent contrast agents are critical for bi

136 inding and activation of a cell-permeant and nontoxic fluorogenic ligand (a so-called fluorogen).

137 f relapsed and chemotherapy-resistant BPL at nontoxic fmol/kg dose levels.

138 salt nanoparticles can be tuned to be either nontoxic for enhanced imaging, or phototoxic for improve

139 ve toward the analyzed cell lines and almost nontoxic for healthy cell, indicating a high specific ac

140 of the intestinal pathogen Vibrio cholerae A nontoxic fragment of the first 386 aa of cholix was gene

141 While many substances were nontoxic, frequent disclosures also included notorious g

142 cury (Hg)-based liquid metal electrodes, the nontoxic Ga alloys maintain high environmental benignity

143 Room-temperature liquid metals, such as nontoxic gallium alloys, show enormous promise to revolu

144 (siRNAs) for highly effective, specific, and nontoxic gene silencing in plants.

145 f the hydroxyguanidine moiety and provided a nontoxic group that could be easily bioactivated by glyc

146 HD was oxidized to the nontoxic HD-sulfoxide.

147 in inside the infected erythrocytes, forming nontoxic hemozoin crystals from large quantities of heme

148 c, so malarial parasites crystallize heme to nontoxic hemozoin.

149 We discovered that fibers are nontoxic if they are washed free of adsorbed nonfibrilla

150 rtant framework for the design of potent and nontoxic immunomodulating agents derived from subglutino

151 and rapamycin (aCD40/rapa) to be a reliable, nontoxic, immunosuppressive regimen for combined islet a

152 forms of drug resistance, and are active and nontoxic in animal infection models.

153 tructs engineered to be cytoplasmic are also nontoxic in HEK293 cells.

154 osomal acidification or degradation and were nontoxic in primary cell cultures.

155 ed time course anticonvulsant studies, being nontoxic in subacute toxicity studies.

156 All BODIPYs were nontoxic in the dark (IC50 > 200 muM) and showed low pho

157 The complex is nontoxic in the dark, with cellular clearance within 96

158 A nontoxic in vivo single-dose evaluation for two binuclea

159 wise, overexpressing a SENP1(Eu) protease is nontoxic in yeast.

160 ene expression levels by administration of a nontoxic inducer will have positive effects on the safet

161 dentification of NEU-617 (1) as a potent and nontoxic inhibitor of proliferation for the HAT pathogen

162 R) may be reversed by selective, potent, and nontoxic inhibitors of ABCG2.

163 Glutamine serves, with alanine, as a major nontoxic interorgan ammonia carrier.

164 s was developed by using iodosylbenzene as a nontoxic iodine(III)-based oxidant and ammonium iodide a

165 rties allowed the selection of 11 (INF39), a nontoxic, irreversible NLRP3 inhibitor able to decrease

166 lead, compound 4, was relatively potent and nontoxic, it exhibited poor stability to oxidative metab

167 osomes containing either silica particles or nontoxic latex particles.

168 H3PbI3, demonstrating that it is a promising nontoxic lead-free replacement for lead iodide perovskit

169 Oral delivery of nontoxic levels of DMG to mice previously inoculated wit

170 eveal that starvation leads to production of nontoxic levels of reactive oxygen species (ROS).

171 unstable ferroptotic lipid hydroperoxides to nontoxic lipid alcohols in a tissue-specific manner.

172 cells processed via a sol-gel process using nontoxic, low boiling point mixed solvents.

173 The method allows rapid, nontoxic measurement of the three-dimensional (3D) spati

174 triking effect was explained by formation of nontoxic metabolites after 1 h incubation in human liver

175 f-life of 160 min, resulting in formation of nontoxic metabolites.

176 This method employs an inexpensive, nontoxic metal source (copper) and incorporates a stable

177 agents were perhydrolyzed to the respective nontoxic methylphosphonic acids.

178 The easily handing, nontoxic, mild, environmentally friendly (green oxidants

179 ons in the buccal network of Aplysia at low, nontoxic Mn(2+) concentrations.

180 CPMV nanoparticles are stable, nontoxic, modifiable with drugs and antigens, and their

181 pressible by QS, and is inducible by a small nontoxic molecule (quinic acid).

182 We suggest that treatment with the small, nontoxic molecule AS101 may be an effective early therap

183 We identified 3 novel, nontoxic molecules demonstrating selective bacterial upt

184 se compounds, we selected the ten top-ranked nontoxic molecules proposed to be experimentally tested

185 t action of cholera toxin (CT) and two novel nontoxic molecules, multiple-mutated CT (mmCT) and doubl

186 igomers in order to maintain the presence of nontoxic monomers and to prevent fibrillization.

187 onto brain membranes much more rapidly than nontoxic monomers and were recovered in part as bound to

188 lly bound synaptotoxic oligomers rather than nontoxic monomers, and the method of oligomer preparatio

189 ibitor presented could provide an effective, nontoxic monotherapy or be used in combination with immu

190 -antigen and core sugars (OAg) of LPS to the nontoxic mutant of diphtheria toxin (CRM(197)).

191 We found that diphtheria toxin and its nontoxic mutant, called CRM197, can interact with HS.

192 iation at pH 7.4 results in the formation of nontoxic, native monomers.

193 ignificantly increased by treatment with the nontoxic, natural disaccharide trehalose.

194 We chose to use trehalose, a nontoxic naturally occurring disaccharide that is found

195 Nontoxic nature and cell membrane permeability are key f

196 f a highly photostable, renal clearable, and nontoxic new NIR probe (CyG) for precise quantification

197 hat PCDD/Fs are reductively dechlorinated to nontoxic non-2,3,7,8 PCDD/F congeners in sewers and land

198 formation and also promotes the formation of nontoxic, nonamyloid amorphous aggregates, which are mor

199 However, nontoxic, nonbactericidal polymyxin derivatives have bee

200 ormaldehyde and NO(x)-providing a relatively nontoxic, noncaustic, and inexpensive source for catalyt

201 entirely of Earth-abundant elements and are nontoxic, nonflammable, and safe for use in residential

202 he effect on HIV replication of trehalose, a nontoxic, nonreducing disaccharide that induces autophag

203 These oligomeric solvents are nontoxic, nonvolatile, and recyclable alternatives to he

204 duction of engineered nanoparticles that are nontoxic or biocompatible, and also allow for the design

205 hic amphipod Melita plumulosa was exposed to nontoxic or reproductively toxic concentrations of coppe

206 excellent radioprotection in mice at single nontoxic oral dose by a dose-reduction factor of 1.28.

207 It is nontoxic, orally bioavailable, metabolically stable, and

208 igated the influence of selected natural and nontoxic organic macromolecules (carboxymethyl cellulose

209 57 mug L(-1) year(-1)), there was a shift to nontoxic, organic aluminum.

210 Importantly, the nontoxic orlandin significantly reduced P. falciparum in

211 ahead to the development of efficacious and nontoxic PAI-1 inhibitors as anticancer agents.

212 -uridine phosphoramidate nucleotide 16, as a nontoxic pan-genotypic anti-HCV agent.

213 phosphoramidate diastereomers 27 and 28, as nontoxic pan-genotypic anti-HCV agents.

214 This precious metal-free and nontoxic photocatalytic system displays better performan

215 a suggest that this self-assembling, largely nontoxic platform may have broad utility for the specifi

216 of the qualities of an ideal reagent: it is nontoxic, plentiful, and inexpensive.

217 e developed from versatile, inexpensive, and nontoxic poly(acrylic acid) hydrogels containing calcium

218 Here, we report that nontoxic poly(ethylene glycol)-functionalized hydrophili

219 d scaffold-hopping approach, more potent and nontoxic polyamido derivatives were identified, highligh

220 In this study, we examined a novel class of nontoxic polycationic compounds initially designed as un

221 pherical dextran nanoparticle assembled from nontoxic polyglucose.

222 arene derivatives has been introduced, using nontoxic potassium thiocyanate as a cyanating reagent in

223 lectively oxidizes CEES to the comparatively nontoxic product 2-chloroethyl ethyl sulfoxide (CEESO) w

224 or rapid and efficient VX degradation to the nontoxic product EMPA (ethyl methylphosphonic acid).

225 ers and can be designed to depolymerize into nontoxic products.

226 lead(II) acetate, bismuth is used due to its nontoxic properties, as Bi(III) has been a reagent in me

227 ty, rapid activation, tumor selectivity, and nontoxic properties, the NIR-ASM appears to be a promisi

228 patients and not showing cross-reactivity to nontoxic proteins such as maize, soya, and rice.

229 n relationship in PSMs, our study identifies nontoxic PSMalpha3 derivatives for active vaccination st

230 = 4 h at 25 degrees C, using inexpensive and nontoxic reagents (NaCl, diluted HCl, water).

231 ve bioorthogonal "click" reactions employing nontoxic reagents are in high demand for their great uti

232 -forming toxin, equinatoxin II (Eqt), into a nontoxic reporter termed Eqt-SM and used it to monitor i

233 to disintegrate the artificial scaffold into nontoxic residues with smaller dimensions to ensure rena

234 oxic hIAPP peptide and the nonamyloidogenic, nontoxic rIAPP peptide remain unclear.

235 Conclusion:(68)Ga-NOTA-UBI is considered a nontoxic, safe-to-administer radiopharmaceutical unlikel

236 n target binding, were metabolically stable, nontoxic, selective, and potent in inhibiting formation

237 Furthermore, nontoxic short UGGAA repeat RNA suppressed mutated RBP a

238 of DU011, our previously discovered potent, nontoxic, small-molecule inhibitor of UPEC polysaccharid

239 s approaches for development of inexpensive, nontoxic solar cell contacting pastes.

240 llization while stabilizing its monomers and nontoxic soluble assemblies of nonfibrillar morphology.

241 3-phenylprop-2-enoate (ethyl cinnamate) as a nontoxic solvent-based clearing reagent that can be hand

242 oxic conformer compared with non-aggregated, nontoxic species or mature fibrils.

243 However, recent studies demonstrated that nontoxic STa derivatives (toxoids), after being fused to

244 TePhe is synthetically accessible, nontoxic, stable under biological conditions, and the te

245 gn of stable, protease-resistant, potent and nontoxic StAMP prototypes.

246 rt through its effect on REV1 is a promising nontoxic strategy to increase p53-dependent cell death a

247 Nanodiamonds are of interest as nontoxic substrates for targeted drug delivery and as hi

248 lar replication using a naturally occurring, nontoxic sugar.IMPORTANCE Induction of autophagy through

249 omoting the formation of more aggregated and nontoxic tau aggregates.

250 Quantitative uptake studies of a nontoxic Tb-containing compound by individual cells were

251 In a nontoxic Tc toxin variant, we can visualize part of the

252 Specifically, we demonstrate that the nontoxic tellurium compound AS101, currently being evalu

253 These features of ESKM make it a promising nontoxic therapeutic agent for sensitive and resistant P

254 ) represent a new, potentially effective and nontoxic therapeutic approach for patients with relapsed

255 ding on these results, we developed a novel, nontoxic therapeutic strategy to target dormant breast c

256 It is inexpensive, earth-abundant, and nontoxic; therefore, it can be used in catalysis, sensor

257 Monophosphoryl lipid A (MPLA), a nontoxic TLR4 ligand derived from lipopolysaccharide (LP

258 A selection assay for nontoxic TNT variants in Escherichia coli identified fou

259 thers reported in the literature while being nontoxic to cells even at high concentrations.

260 The sensor by itself is nontoxic to cells in culture and has been used to monito

261 2 is nontoxic to cells, but potently cytotoxic to cancer cell

262 chables at pH 7 from all the composites were nontoxic to dental pulp stem cells.

263 The complexes were nontoxic to either bacterial or mammalian cells.

264 on of lung cancer cells in vitro while being nontoxic to endothelial cells.

265 hly active to cancer cells and less toxic or nontoxic to fibroblasts.

266 oxicity studies reveal that the alt-PASs are nontoxic to HEK, HeLa, and NIH3T3 cells.

267 gents were shown to be chemically stable and nontoxic to HEK293T cells at concentrations as high as 5

268 ar growth of Mycobacterium tuberculosis, are nontoxic to human cell lines, and are active against mul

269 anti-HIV and anti-HBV inhibitor, while being nontoxic to human hepatoblastoma cells.

270 as PLLA is biocompatible, biodegradable and nontoxic to humans.

271 nm aggregates, the aggregates are stable and nontoxic to macrophage cells up to 55 x 10(-3) m Au.

272 en coadministered with 36 (at concentrations nontoxic to mammalian cells), the minimum inhibitory con

273 While nontoxic to mammalian cells, the single-site variant has

274 The peptide was bactericidal and nontoxic to mammalian cells.

275 omising compound in the series, HSGN-218, is nontoxic to mammalian colon cells and is gut-restrictive

276 ACHP, but not IKK 16, was nontoxic to mouse or human keratinocytes at any dose tes

277 Nontoxic to myeloma cells when used as a single agent, 4

278 In addition, CQ is nontoxic to neuronal cells and shows significant blood b

279 he proliferation of cancer cells while being nontoxic to normal cells.

280 and human MPNST cell lines, while remaining nontoxic to normally dividing Schwann cells or mouse emb

281 tably, the optimized molecule is shown to be nontoxic toward human cells (HEK 293) at a concentration

282 Nontoxic toward mammalian cells, these rapidly bacterici

283 kB antagonist cyclotraxin-B was fused to the nontoxic transduction domain of the tat protein from hum

284 to overcome using siRNA, we also developed a nontoxic transfection vector: poly(lactic-coglycolic aci

285 ions via a cheap, highly atom-efficient, and nontoxic transition-metal free aldol polycondensation.

286 A new class of nontoxic triaryl benzimidazole compounds, derived from e

287 An effective, nontoxic, tumor-specific immunotherapy is the ultimate g

288 table for therapy must be both effective and nontoxic, typical screening focuses on efficacy, whereas

289 merized right after use, the best siCPDs are nontoxic under conditions where cell-penetrating peptide

290 ults demonstrate that doses of MDMA that are nontoxic under cool, quiet conditions can become highly

291 ct based HDAC inhibitors, 4a was found to be nontoxic under in vivo conditions.

292 equently encountered in clinical practice in nontoxic uninodular or multinodular goiter.

293 nstrate that RNA labeling with the modified, nontoxic uridine analog 5-ethynyl uridine (5-EU) in Arab

294 The identification of nontoxic variants of L9 strongly suggests that it is a n

295 d cell tropism of HSV, our design provides a nontoxic vector that can accommodate large transgene con

296 Importantly, the nontoxic, vinyl ether duocarmycin double prodrug was suc

297 Finally, although largely reported as nontoxic, we have found that chitosan, as either polyple

298 dly without inducing drug resistance and was nontoxic when applied topically.

299 insoluble and stable Abeta species that were nontoxic which indicates that p-FTAA might have therapeu

300 Both compounds are nontoxic with ideal pharmacokinetic properties for furth