ライフサイエンスコーパス: nub

1 Here, we show that NUBBIN (NUB), a gene closely related to JAG, is responsible for

2 Overall, we propose that nub acts downstream of Notch on the distal part of insec

3 nd gynoecium development, where we find that NUB acts redundantly with JAG to promote the growth of t

4 asciatus (milkweed bug), showed that nubbin (nub) affects antenna morphogenesis, labial patterning, t

5 ession through this silencer also depends on nub, allowing pdm2 to fully respond to the wing enhancer

6 JAG and NUB also act redundantly to promote the differentiation

7 lso show that despite shifting position, the Nub and Tsh domain boundaries, like compartment boundari

8 Unlike classical compartments, the Nub and Tsh domains do not define absolute lineage restr

9 s of the wing and mammalian rhombomeres, the Nub and Tsh domains share some of the attributes of clas

10 Once established, the Nub and Tsh domains, and the intervening region in which

11 due to regulation by Wingless signaling, the Nub and Tsh expression boundaries shift during developme

12 omains of two transcription factors, Nubbin (Nub) and Teashirt (Tsh), present in distal and proximal

13 rane spanning macromolecules linked to these nubs are also attached to the AZM macromolecules.

14 e is nearly the same vesicle to vesicle, and nubs, at their sites of connection to the vesicle membra

15 Both the NEMO ubiquitin-binding (NUB) domain and the zinc-finger (ZF) domain of NEMO medi

16 all constructs functioned properly with a Tc-nub enhancer in Drosophila, complications arose with tis

17 ibia), and in this species we also show that nub expression in the legs is regulated by Notch signali

18 2 to fully respond to the wing enhancer when nub expression is perturbed and functional compensation

19 of-function experiments showing that ectopic NUB expression is sufficient to drive the proliferation

20 Similarly, our re-analysis of nub function in Drosophila reveals that legs lack all tr

21 irst functional evidence defining a role for nub in leg segmentation and highlight the varying degree

22 Unlike JAG, NUB is exclusively expressed in leaves, stamens and carp

23 ends into all cell layers of lateral organs, NUB is restricted to the interior adaxial side.

24 Few SCCs were located on small nub-like papillae during the parasitic juvenile stage, b

25 The nub of the problem lies in the inherent variability of t

26 Posterior embryotoxon appeared as nubs of whorled collagen extending from the corneal stro

27 The connection sites of most nubs on the membrane of docked vesicles are paired with

28 logs of Drosophila temporal identity factors nub/pdm2, regulate the timely production of cones in mic

29 In addition, we find that the distal factor Nub represses the ligand unpaired as well as Stat92E act

30 ir ability to respond to this enhancer, with nub responding in all wing progenitor cells and pdm2 onl

31 While both Acheta and Periplaneta nub-RNAi first nymphs develop crooked antennae, no visib

32 of these two segments and creates a chimeric nub-RNAi tibia-tarsus that retains a tibial identity in

33 e density at veil margins, and protrusion of nubs that transform into filopodia.

34 In cells with two short branches or nubs, the proteins oscillated symmetrically from one end

35 2) "axial" filaments connect focal rings to nub tips, thereby organizing filament bundling and ensur

36 cromolecules attached by narrow projections, nubs, to the vesicle membrane at approximately 25 sites.

37 described, but a peripheral corneal stromal nub variable in location with abnormal extracellular mat

38 These nubs were located anterior to Schwalbe's line (n = 4), p