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1 of polarization between these nuclei via the nuclear Overhauser effect.
2 en determined using the exchange-transferred nuclear Overhauser effect.
3 ner similar to the spin-polarization induced nuclear Overhauser effect.
4 GCG) has been determined using time-averaged nuclear Overhauser effects.
5 shift dispersion, and negative heteronuclear nuclear Overhauser effects.
6 rsion, and negative (1)H-(15)N heteronuclear nuclear Overhauser effects.
7 eristic sequential and mid-range transferred nuclear Overhauser effects.
8 e relaxation rates and amide nitrogen-proton nuclear Overhauser effects.
9 nd tert-butyl groups was readily detected by nuclear Overhauser effects.
10 shifts and were confirmed by measurements of nuclear Overhauser effects.
11 pocket was defined through 37 intermolecular nuclear Overhauser effects.
12 relaxation times, T1 and T2, and the 1H-15N nuclear Overhauser effect (1H-15N NOE) indicates that mo
13 ls, was determined utilizing two-dimensional nuclear Overhauser effect (2D NOE) and double-quantum-fi
14 duplex have been made using two-dimensional nuclear Overhauser effect (2D NOE) spectra, at three dif
15 nothiazine and detection of isotope-filtered nuclear Overhauser effects allowed identification of dru
17 resonance techniques using 1290 experimental nuclear Overhauser effect and dipolar coupling constrain
18 spectroscopy in D2O (NOESY (two-dimensional nuclear Overhauser effect and exchange spectroscopy) at
19 nd proton cross-peaks were well dispersed in nuclear Overhauser effect and heteronuclear single quant
23 nstraints based on the observed magnitude of nuclear Overhauser effects and 58 torsion angle restrain
25 e conformations responsible for the observed nuclear Overhauser effects and inter-nuclear coupling.
26 ined structure as indicated by the number of nuclear Overhauser effects and is shown to play a critic
28 ular modeling and NMR spectroscopy including nuclear Overhauser effects and residual dipolar coupling
29 ith aliphatic resonances in [Ca(2+)](4)-CaM (nuclear Overhauser effect) and increases the Ca(2+) affi
30 h-affinity complexes using (15)N R(1), R(2), nuclear Overhauser effect, and chemical-shift anisotropy
31 d D-LDH, such as the chemical shift changes, nuclear Overhauser effect, and solvent-induced isotopic
32 ere chemical shift assignments, (15)N-edited nuclear Overhauser effects, and (1)H-(15)N residual dipo
33 Sequential NMR assignments, intramonomer nuclear Overhauser effects, and circular dichroism spect
34 ts has been obtained using NMR spectrometry, nuclear Overhauser effects, and density functional theor
35 ents using (15)N-(13)C-labeled protein, (1)H nuclear Overhauser effects, and longitudinal relaxation
36 netic relaxation enhancement, intermolecular nuclear Overhauser effects, and targeted mutagenesis con
42 inal and transverse 13C relaxation rates and nuclear Overhauser effects at both 500 and 600 MHz (prot
44 n firmly assigned through (a) measurement of nuclear Overhauser effect connectivities, (b) prediction
45 dence of these H3(+) resonance; and observed nuclear Overhauser effects consistent with Hoogsteen and
46 ogram CYANA to build a network of interchain nuclear Overhauser effect constraints that can be used t
47 acetylated peptide and by weak medium-range nuclear Overhauser effect contacts indicative of alpha-h
48 ymmetric dimer interface, 172 intermolecular nuclear Overhauser effect correlations (NOEs) define the
49 ents Using Satisfiability (MAUS), leveraging Nuclear Overhauser Effect cross-peak data, peak residue
50 the membrane, as supported by intermolecular nuclear Overhauser effect cross-peaks between the peptid
53 were modeled using experimental transferred nuclear Overhauser effect data derived upon binding R*.
54 he conformational ensemble obtained by using nuclear Overhauser effect data in structure calculations
55 r proteins in solution from experimental NMR nuclear Overhauser effect data only and with minimal ass
59 cture was solved based on homonuclear proton nuclear Overhauser effect data using complete relaxation
64 a-helical membrane proteins >15 kDa in size, Nuclear-Overhauser effect-derived distance restraints ar
65 of the resulting alkenes were established by nuclear Overhauser effect difference NMR spectroscopy.
74 d question mark1H inverted question mark-15N nuclear Overhauser effects for the 15N nuclear spins usi
78 and (iii) selective detection of (19)F-(19)F nuclear Overhauser effects in the Escherichia coli pepti
79 ies done by using the heteronuclear [1H]-15N nuclear Overhauser effect indicate that almost half of P
82 agnetic resonance spectroscopy, based on 905 nuclear Overhauser effect inter-proton distance restrain
85 contact zone derived from the intermolecular nuclear Overhauser effects is in agreement with recent b
88 R2) and steady state heteronuclear 15N [1H] nuclear Overhauser effect measurements at 500 and 600 MH
89 ic resonance line-broadening and transferred nuclear Overhauser effect measurements to identify the m
90 Furthermore, based on exchange-transferred nuclear Overhauser effect measurements, we established t
92 hermal titration calorimetry, intermolecular nuclear Overhauser effects, mutagenesis, and protection
93 ts derived from a combination of transferred nuclear Overhauser effect NMR experiments and molecular
95 en determined by two-dimensional transferred nuclear Overhauser effect NMR spectroscopy at 600 MHz.
96 have been studied in aqueous solutions using nuclear Overhauser effect (NOE) and transferred NOE NMR
97 ore region as evidenced by an intermolecular nuclear Overhauser effect (NOE) between each metallopept
98 Analyses of NMR chemical shifts and backbone nuclear Overhauser effect (NOE) connectivities showed th
99 ent was based on 2778 unambiguously assigned nuclear Overhauser effect (NOE) connectivities, 297 ambi
106 ts, and distance restraints derived from the nuclear Overhauser effect (NOE) data were used to calcul
109 l and transverse relaxation rates and 15N-1H nuclear Overhauser effect (NOE) enhancements were measur
110 ) detection of intermolecular contacts using nuclear Overhauser effect (NOE) experiments; (iv) struct
112 in relaxation rate (R(2)), and heteronuclear nuclear Overhauser effect (NOE) have been carried out at
113 we support these assignments with sequential nuclear Overhauser effect (NOE) information obtained fro
114 between different (1)H environments via the nuclear Overhauser effect (NOE) is included in the NMR p
115 relaxation times made it impractical to use nuclear Overhauser effect (NOE) measurements for assignm
117 cytochrome b5 were quantified using {1H}-15N nuclear Overhauser effect (nOe) measurements, which char
119 he 13C relaxation data, T1, and steady-state nuclear Overhauser effect (NOE) obtained at two differen
120 geous when classical NMR parameters like the nuclear Overhauser effect (NOE) or J-couplings fail.
123 tative distance restraints, analogous to the nuclear Overhauser effect (NOE) routinely used in soluti
124 emical shift, T1 values, and one-dimensional nuclear Overhauser effect (nOe) saturation transfer expe
125 omplete relaxation matrix methods to analyze nuclear Overhauser effect (NOE) spectroscopic cross-peak
126 ermining resonance assignments, interpreting nuclear Overhauser effect (NOE) spectroscopy (NOESY) spe
128 C-(13)C-(1)H correlation and (15)N-separated nuclear Overhauser effect (NOE) spectroscopy experiments
131 rted question mark-HN inverted question mark nuclear Overhauser effect (NOE) values of vMIP-II, deter
133 the steep inverse distance dependence of the nuclear Overhauser effect (NOE), from which the distance
135 (r.m.s.d.) = 1.2 A] was determined from 475 nuclear Overhauser effect (NOE)-derived distance restrai
137 angstrom2 were generated with a total of 500 nuclear Overhauser effect (NOE)-derived distance restrai
138 m the human RBCC protein, MID1) based on 670 nuclear Overhauser effect (NOE)-derived distance restrai
139 ed interactions and violated very few of the nuclear Overhauser effect (NOE)-derived distances used i
143 erse relaxation rate (R2), and heteronuclear nuclear Overhauser effect (NOE)] measured at two tempera
145 876 upper distance constraints derived from nuclear Overhauser effects (NOE) and 173 dihedral angle
146 1878 upper distance constraints derived from nuclear Overhauser effects (NOE) and 314 dihedral angle
147 pendent on the observation of intermolecular nuclear Overhauser effects (NOE) and their assignments,
149 on rate constants (RN(Nx,y)=1/T2) and 1H-15N nuclear Overhauser effects (NOE) were obtained for 143 o
156 domain without an inhibitor is based on 2813 nuclear Overhauser effects (NOEs) and has an average RMS
157 ossibly differences in homonuclear (1)H-(1)H nuclear Overhauser effects (NOEs) and heteronuclear (1)H
158 structure was determined on the basis of the nuclear Overhauser effects (NOEs) and the hydrogen bond
159 intensity of both sequential and long-range nuclear Overhauser effects (NOEs) between backbone amide
163 easure (13)C T(1), T(1rho) and heteronuclear nuclear Overhauser effects (NOEs) for sugar and base nuc
164 ns and nitrogens, and (1)H-(1)H interresidue nuclear Overhauser effects (NOEs) for the two mutants wi
165 to DNA chemical shifts and 24 intermolecular nuclear Overhauser effects (NOEs) identify the 5'-ApG an
166 g, chemical shift mapping and intermolecular nuclear Overhauser effects (NOEs) indicate the presence
168 stance and angular restraints based on 1H-1H nuclear Overhauser effects (NOEs), hydrogen-bonding netw
170 Using paramagnetic probes and protein-DPC nuclear Overhauser effects (NOEs), we define portions of
176 J couplings, isotropic chemical shifts, and nuclear Overhauser effects (NOEs)/rotational frame nucle
178 ifts (CSs), intensities of NOESY crosspeaks [nuclear Overhauser effects (NOEs)], and residual dipolar
179 of r-K2 (1)H-NMR signals and two-dimensional nuclear Overhauser effect (NOESY) experiments in the pre
182 degrees), the set of medium- and short-range nuclear Overhauser effects observed for the active N-ter
184 usion rates, the NH chemical shifts, and the nuclear Overhauser effect patterns provided a coherent p
185 ntribution of conformational exchange to the nuclear Overhauser effect peak intensity, we applied inf
186 sonance assignments and detailed analysis of nuclear Overhauser effects permit the direct comparison
187 ts, coupling constants, relaxation rates and nuclear Overhauser effect prediction applied to the thre
189 pecific (15)N-T(1), (15)N-T(2), (15)N-{(1)H} nuclear Overhauser effect, reduced spectral density, and
190 Spin-lattice, spin-spin, and heteronuclear nuclear Overhauser effect relaxation data for backbone a
191 NMR experiments (correlated chemical shifts, nuclear Overhauser effects, residual dipolar couplings)
192 ust and has a high tolerance for misassigned nuclear Overhauser effect restraints, greatly simplifyin
195 ion matrix simulation of the two-dimensional nuclear Overhauser effect spectra at various mixing time
197 hanges upon Zn(2+) binding were supported by nuclear Overhauser effect spectrometry (NOESY) studies.
198 centers was assigned through two-dimensional nuclear Overhauser effect spectroscopic analysis coupled
199 evertheless, structure calculations based on nuclear Overhauser effect spectroscopic data combined wi
200 The two distinct structures are derived from nuclear Overhauser effect spectroscopic distance restrai
202 cal shift measurements, two-dimensional (2D) nuclear Overhauser effect spectroscopy (2D-NOESY) 1H MAS
205 thiol (PTs)] were isolated and identified by nuclear Overhauser effect spectroscopy (NOESY) correlati
206 ance (NMR) experiments, and (5) NMR transfer nuclear Overhauser effect spectroscopy (NOESY) experimen
207 ized by variable temperature NMR studies and nuclear Overhauser effect spectroscopy (NOESY) experimen
209 methyl groups that is based on methyl-methyl nuclear Overhauser effect spectroscopy (NOESY) peak list
210 This, in combination with two-dimensional nuclear Overhauser effect spectroscopy (NOESY) results,
211 cts versus their free components, whereas 2D nuclear Overhauser effect spectroscopy (NOESY) spectra s
212 molecule tend to correlate together in a 2D nuclear Overhauser effect spectroscopy (NOESY) spectrum,
213 thin the same molecule may correlate in a 2D nuclear Overhauser effect spectroscopy (NOESY) spectrum,
214 g (RFDR) and (1)H magic angle spinning (MAS) nuclear Overhauser effect spectroscopy (NOESY) technique
216 combination of (1)H NMR and two-dimensional Nuclear Overhauser Effect Spectroscopy (NOESY) which rev
217 SY), total correlation spectroscopy (TOCSY), nuclear Overhauser effect spectroscopy (NOESY), and rota
219 )C relaxation parameters, and rotating-frame nuclear Overhauser effect spectroscopy (ROESY) crosspeak
220 ect spectroscopy (NOESY), and rotating frame nuclear Overhauser effect spectroscopy (ROESY) data were
221 re determined by transferred two-dimensional nuclear Overhauser effect spectroscopy (TRNOESY) measure
222 n the present work, we have used transferred nuclear Overhauser effect spectroscopy (TRNOESY) to dete
227 ion-ordered spectroscopy, and rotating-frame nuclear Overhauser effect spectroscopy and high-resoluti
228 esidues near Trp191, as shown by transferred nuclear Overhauser effect spectroscopy and hydrogen/deut
231 VSD-phospholipid micelle interactions using nuclear Overhauser effect spectroscopy and showed that t
234 site as reflected in optical spectra and NMR nuclear Overhauser effect spectroscopy cross-peak and hy
237 itionally, NMR(2) relies on isotope-filtered nuclear Overhauser effect spectroscopy experiments requi
238 no-7-iminoindolizin-1-ones) were rejected by nuclear Overhauser effect spectroscopy experiments.
239 ucture of the two isomers is determined with nuclear Overhauser effect spectroscopy NMR and single-cr
242 This method includes the acquisition of nuclear Overhauser effect spectroscopy one-dimensional a
245 trad-bound guanine can be extracted from the nuclear Overhauser effect spectroscopy spectrum based on
248 ct, we have used two-dimensional transferred nuclear Overhauser effect spectroscopy to determine the
249 version recovery method, and the transferred nuclear Overhauser effect spectroscopy was used to study
250 0) IKENLKDCGLF was determined by transferred nuclear Overhauser effect spectroscopy while it was boun
251 d annealing using structural restraints from nuclear Overhauser effect spectroscopy, and scalar and r
253 R spectra, total correlated spectroscopy and nuclear Overhauser effect spectroscopy, show that the mo
254 ation, which is confirmed by two-dimensional nuclear Overhauser effect spectroscopy, the crystal stru
255 (K(a) up to 19,000 M(-1)), and is shown--by nuclear Overhauser effect spectroscopy--to adopt the thr
261 as measured by NMR experiments of (1)H-(15)N nuclear Overhauser effect, spin-lattice relaxation, and
264 internally inconsistent group of long range nuclear Overhauser effects suggest a close proximity of
265 axation-dispersion experiments, and filtered nuclear Overhauser effects suggest that CCL27 does not a
266 R1) or heteronuclear cross relaxation rates (nuclear Overhauser effect), suggesting that the 14-38 di
267 exhibits fewer helix-related and long range nuclear Overhauser effects than does the d-Ser(B8) analo
268 As monitored by two-dimensional (19)F-(19)F nuclear Overhauser effect, the distance between two phen
270 d, and their relaxation, dipolar shifts, and nuclear Overhauser effects to adjacent residues used to
271 an NMR experiment that allows one to exploit nuclear Overhauser effects to determine internuclear dis
272 gion of the talin rod and use intermolecular nuclear Overhauser effects to determine the structure of
274 ositioned in the heme cavity on the basis of nuclear Overhauser effects to the heme and each other, d
277 In previous work, we found using transferred nuclear Overhauser effect (trNOE) analysis that two 13 a
278 ectroscopy experiments, inducing transferred nuclear Overhauser effect (trNOE) and saturation transfe
282 d nucleotide was determined from transferred nuclear Overhauser effects (trnOe) experiments to determ
283 contact surfaces are studied by transferred nuclear Overhauser effects (trNOEs) and saturation trans
286 re determined by two-dimensional transferred nuclear Overhauser effect (TRNOESY) measurements combine
287 re determined by two-dimensional transferred nuclear Overhauser effect (TRNOESY) measurements combine
292 relaxation data and steady-state (1)H- (15)N nuclear Overhauser effects were analyzed using model-fre
293 frame relaxation rates and the heteronuclear nuclear Overhauser effects were carried out on a uniform
295 d question mark1H inverted question mark-15N nuclear Overhauser effects were measured for the backbon
297 y arising from changes in creatine level and nuclear overhauser effects, which were not found using c
299 striking enhancement of multiple native-like nuclear Overhauser effects within the tethered protein.