ライフサイエンスコーパス: nuclear accumulation

1 substitutions at these sites enhanced ICAP1 nuclear accumulation.

2 stability of the protein and suppressed its nuclear accumulation.

3 cellular G-actin concentration control their nuclear accumulation.

4 within this N-terminal region inhibit ICAP1 nuclear accumulation.

5 with protoporphyrin IX zinc(II) blocked MLP nuclear accumulation.

6 tability in the nucleus, thereby slowing its nuclear accumulation.

7 ncreased the DOX release and facilitated its nuclear accumulation.

8 YC phosphorylation cascade that promoted MYC nuclear accumulation.

9 ntreated patients with AML, leading to eIF4E nuclear accumulation.

10 nteractions through directly regulating YAP1 nuclear accumulation.

11 se aortic constriction (TAC) because of GRK5 nuclear accumulation.

12 o interact with beta-catenin, inhibiting its nuclear accumulation.

13 SO levels, suggesting potential roles in ASO nuclear accumulation.

14 in fibroblasts, despite its TNFalpha-induced nuclear accumulation.

15 erminal regulatory domain that restricts its nuclear accumulation.

16 elevated temperatures, and extra-centromeric nuclear accumulation.

17 er store-operated Ca2+ entry (SOCe) and NFAT nuclear accumulation.

18 are required for both nuclear exclusion and nuclear accumulation.

19 r(194) and Pin1 at Ser(16), as well as their nuclear accumulation.

20 ikely in cytosolic foci that regulate PERIOD nuclear accumulation.

21 Cdc24 cellular localization, preventing its nuclear accumulation.

22 me the principal targeting signal conferring nuclear accumulation.

23 m a loss of cytoplasmic HDAC4 as well as its nuclear accumulation.

24 ner, and Hog1 is required for Rtg1/3 complex nuclear accumulation.

25 ), stabilizing the transcript and supporting nuclear accumulation.

26 cific post-translational regulation of HBL-1 nuclear accumulation.

27 d by decreased phosphorylation and increased nuclear accumulation.

28 xposure, and occurred without significant GR nuclear accumulation.

29 ive stretch, suggesting that HDACs block MLP nuclear accumulation.

30 ore, we found that PWR is important for HDA9 nuclear accumulation.

31 und that blocks exportin 1 (XPO1) and forces nuclear accumulation and activation of tumor suppressor

32 ells, knockdown of E-cad or alpha-cat caused nuclear accumulation and activation of YAP without overt

33 Mechanistically, ROS triggers AhR nuclear accumulation and activation to promote the trans

34 Germline removal increases MML-1 nuclear accumulation and activity.

35 lization that restricts TGFbeta-induced Smad nuclear accumulation and activity.

36 -127 in YAP1, coinciding with increased YAP1 nuclear accumulation and activity.

37 Additionally, HOS15 regulates HDA9 nuclear accumulation and chromatin association.

38 urs at a late post-entry step, with both the nuclear accumulation and chromosomal integration of nasc

39 cells with suppressed PDLIM2 exhibit reduced nuclear accumulation and deneddylation activity of the C

40 Cdc14 activation at anaphase triggers nuclear accumulation and enzymatic activation of Yen1, l

41 Concurrent GAPDH nuclear accumulation and ERK inhibition were required, h

42 ice indicate that deacetylation favors FoxO1 nuclear accumulation and exerts target gene-specific eff

43 thase kinase 3beta inhibition leads to FANCC nuclear accumulation and FA pathway activation, as measu

44 ant mechanism that selectively regulates the nuclear accumulation and function of HIF-1alpha and pote

45 DAF-16 (in the daf-16 (mu86); muIs61 strain) nuclear accumulation and high expression of the SOD-3 ge

46 COP1 in the regulation of UV-B-induced UVR8 nuclear accumulation and in UVR8-mediated UV-B signaling

47 ary cultured neurons, NES mutations increase nuclear accumulation and increase overall aggregation.

48 The latter is triggered by the nuclear accumulation and increased transcriptional activ

49 Additionally, rhubarb inhibited beta-catenin nuclear accumulation and induced its degradation via pro

50 al activity, evidenced by the increased Nrf2 nuclear accumulation and its downstream gene expression.

51 apid cellular uptake, evident enhancement of nuclear accumulation and less drug efflux in the resista

52 duced alphavbeta3 expression, enhancing Slug nuclear accumulation and MaSC clonogenicity.

53 ith the NFAT blocker A-285222 reduced NFATc3 nuclear accumulation and NFAT-luciferase transcriptional

54 exon during virus replication, driving hexon nuclear accumulation and particle assembly.

55 gf stimulates beta-catenin stabilization and nuclear accumulation and protects against epithelial cel

56 d post-translational modifications, inducing nuclear accumulation and regulation of target genes.

57 n importin inhibitor, blocked HE4/importin-4 nuclear accumulation and sensitized HE4-overexpressing o

58 FA also rapidly induced nuclear accumulation and Ser326 phosphorylation of the m

59 ore, the absence of 14-3-3sigma leads to the nuclear accumulation and stabilization of c-Jun, suggest

60 tion of CRABPII at K102 is essential for its nuclear accumulation and subsequent activation of RA sig

61 and proteasomal degradation but promote its nuclear accumulation and subsequent increased transcript

62 TRIM28 stabilizes and promotes the nuclear accumulation and toxicity of both proteins.

63 n of Lats, dephosphorylation of YAP, and YAP nuclear accumulation and transcriptional activation of i

64 Mechanistic investigations revealed that the nuclear accumulation and transcriptional activity of ARv

65 cell cycle reentry, mediated by independent nuclear accumulation and transcriptional activity of fir

66 ytosol and impaired TGF-beta-induced Smad2/3 nuclear accumulation and transcriptional activity.

67 ed AAV capsids, thereby leading to increased nuclear accumulation and transduction.

68 iting beta-catenin neddylation increases its nuclear accumulation and Wnt/beta-catenin signaling.

69 he tyrosine kinase inhibitor BIBF1120, Rad51 nuclear accumulation, and cell cycle arrest at G(2)/M.

70 evealed differences in their cytoplasmic and nuclear accumulation, and data from quantitative PCR ana

71 epeat containing E3 ubiquitin protein ligase nuclear accumulation, and iii) Fyn phosphorylation.

72 nsing of S. aureus RNA, which triggered IRF5 nuclear accumulation, and this could be antagonized by c

73 However, SKN-1 activity and nuclear accumulation are not always correlated, suggesti

74 Critically, blocking afadin nuclear accumulation attenuated activity-dependent dendr

75 PRMT1 or PRMT4 knockdown did not block Nrf2 nuclear accumulation but inhibited Nrf2 binding to the A

76 ly, their treatments do not facilitate SKN-1 nuclear accumulation, but slightly increased intracellul

77 a HDACs in cardiac muscle, resulting in HDAC nuclear accumulation, but this has not been examined in

78 ors that undergo daily changes in levels and nuclear accumulation by means of complex multisite phosp

79 but bypassing the COP1 requirement for UVR8 nuclear accumulation did not rescue the cop1 mutant UV-B

80 OSM/STAT3 activation promoted SMAD3 nuclear accumulation, DNA binding and induced SMAD3-depe

81 ox dramatically decreases the protein level, nuclear accumulation, DNA binding, and transcriptional a

82 from the androgen receptor by inhibiting its nuclear accumulation downstream of microtubule stabiliza

83 Moreover, Rgf1p nuclear accumulation during replication arrest depends o

84 Nuclear accumulation dynamics were initially rapid, cell

85 morigenicity and, conversely, that promoting nuclear accumulation enhances this, providing the first

86 progression, Ser-33 phosphorylation, and p53 nuclear accumulation from SEPW1 depletion require mitoge

87 ed cells and that active PAK4 inhibits ICAP1 nuclear accumulation in a Ser-10-dependent manner.

88 oM concentration, concomitant with reduced C nuclear accumulation in infected cells.

89 The reduced nuclear accumulation in IRS1KO was due to protein instab

90 cin-induced FOXO3a Ser-7 phosphorylation and nuclear accumulation in MCF-7 cells.

91 after PH; however, HDAC5 exhibited transient nuclear accumulation in regenerating liver.

92 e induces the rapid induction of Arc and its nuclear accumulation in striatal neurons.

93 In vivo measurements of phyB nuclear accumulation in the absence of PIF1, -3, -4, and

94 P3 is required for timely NRF2 induction and nuclear accumulation in the estrogen receptor (ER)-posit

95 ants G12S and H50R induce PTEN oxidation and nuclear accumulation in thyroid cancer.

96 phosphorylated at these sites leading to its nuclear accumulation, increased association with pol III

97 We report here that GRK5 nuclear accumulation is dependent on Ca(2+)/calmodulin (

98 or nuclear export sequence demonstrates that nuclear accumulation is required for toxicity in the Dro

99 his model, our data reveal that beta-catenin nuclear accumulation is restricted to the late stage of

100 ever, the mechanism by which CaM facilitates nuclear accumulation is unknown.

101 leus, and certain gene mutations trigger its nuclear accumulation leading to cell transformation and

102 Microscopic evidence of aberrant nuclear accumulation of 5.8S rRNA in La cKO is supported

103 osolic Ca(2+) stimulate the rapid uptake and nuclear accumulation of a DNA-binding fluorescent cation

104 , and HsLap2beta are not sufficient to drive nuclear accumulation of a membrane protein in yeast, but

105 Notably, Ras-induced nuclear accumulation of activated MEK1/2 was reliant on

106 h TGF-beta receptor I (TbetaRI) and inhibits nuclear accumulation of activated Sma- and Mad-related p

107 the cytoplasm and suggest that LSm8 controls nuclear accumulation of all LSm2-7 proteins.

108 ta-cat) and T-cell factor (TCF) and that the nuclear accumulation of alpha-cat depends on beta-cat.

109 Nuclear accumulation of AMPK complexes containing gamma2

110 using specific antisense morpholino promoted nuclear accumulation of beta-catenin and caused ventrali

111 yos, depletion of IQGAP1 reduced Wnt-induced nuclear accumulation of beta-catenin and expression of W

112 In a panel of RCC cell lines, we observed nuclear accumulation of beta-catenin and increased AURKA

113 Nuclear accumulation of beta-catenin and its transcripti

114 nt signaling orchestrates a response through nuclear accumulation of beta-catenin in the cell populat

115 robe the dynamics of signaling by monitoring nuclear accumulation of beta-catenin, the primary transd

116 vation of Smad signaling, leading to reduced nuclear accumulation of beta-catenin, which is crucial f

117 tein degradation as well as reduction of the nuclear accumulation of beta-catenin.

118 xpression of Wnt target genes, and prevented nuclear accumulation of beta-catenin.

119 es partial skipping of the in-frame exon and nuclear accumulation of beta-catenin.

120 t methylation of YAP facilitates Wnt-induced nuclear accumulation of beta-catenin.

121 in Wnt ligand-independent stabilization and nuclear accumulation of betacatenin.

122 C-terminal SIMs blocks export and allows the nuclear accumulation of BGLF4.

123 ith c-ABL in the cytoplasm, thereby blocking nuclear accumulation of c-ABL and phosphorylation of p73

124 3 blocked the iron-induced up-regulation and nuclear accumulation of CCAAT/enhancer-binding protein-d

125 liferation of immune cells, characterized by nuclear accumulation of cell cycle inhibitors, and prese

126 recombinant viruses was functional, inducing nuclear accumulation of cellular poly(A)-binding protein

127 is a ligand for steroidogenic factor 1, and nuclear accumulation of ceramide has been implicated in

128 Nuclear accumulation of Chk1 in CMA-deficient cells comp

129 of intracellular Ca(2+) with ATP caused the nuclear accumulation of ChREBP.

130 onsive element-binding protein) shut-off and nuclear accumulation of class IIa histone deacetylases.

131 IRT1 deficiency induces hyperacetylation and nuclear accumulation of CRABPII, enhancing RA signaling

132 ve night, a brief light pulse induced strong nuclear accumulation of CRTC1 in the SCN.

133 duce the expression of dFmr1 and promote the nuclear accumulation of dFMR1.

134 lexes showed rapid endosomal trafficking and nuclear accumulation of DNA while DOPC-containing formul

135 The nuclear accumulation of DNAS1L3, but not its exit out of

136 ore, we demonstrate that IGFBP2 augments the nuclear accumulation of EGFR to potentiate STAT3 transac

137 Nuclear accumulation of eIF4E in patients who have AML i

138 ERK/RSK axis, DR5 upregulation, and elevated nuclear accumulation of Elk1 and CHOP.

139 plexes can interact with PPARalpha to effect nuclear accumulation of FABP and NHR activation.

140 Nuclear accumulation of FABP on drug binding is driven l

141 We further show that nuclear accumulation of FABP1 and FABP2 is dependent on

142 aling pathways by CSE deficiency resulted in nuclear accumulation of Forkhead box protein O1 and subs

143 -Aza-2-deoxycytidine (5-azadC) induced rapid nuclear accumulation of FOXO3, ATM-dependent CREB phosph

144 Nuclear accumulation of Foxo3a is augmented by a decreas

145 when NF-YC10 is deficient, the heat-induced nuclear accumulation of GAPC is suppressed, or the GAPC-

146 IGF1 and PE both increased nuclear accumulation of GATA4 and phosphorylation at Ser

147 et-7-family microRNA activity, and decreased nuclear accumulation of HBL-1 via action of the lin-28-l

148 IN-46 is necessary and sufficient to prevent nuclear accumulation of HBL-1.

149 t that PTH-mediated Sost repression involves nuclear accumulation of HDAC inhibiting the MEF2-depende

150 A similar nuclear accumulation of HDAC4 and HDAC5 was observed in

151 n, HDAC4, HDAC5, and HDAC9, and also induced nuclear accumulation of HDAC4.

152 ity leads to HDAC4 dephosphorylation and the nuclear accumulation of HDAC4.

153 ppression was associated with specific rapid nuclear accumulation of HDAC5 and co-localization with M

154 ol (ISO) or PKA activation results in strong nuclear accumulation of HDAC5 in contrast to nuclear exp

155 sphate (cAMP) signaling induce the transient nuclear accumulation of HDAC5 in rodent striatum.

156 Moreover, nuclear accumulation of HDAC5 under acute ISO/PKA signal

157 P-dependent signaling pathway that regulates nuclear accumulation of HDAC5, suggesting a mechanism to

158 lavine drug to HSV-1-infected mice inhibited nuclear accumulation of HIF-1alpha and HIF-2alpha protei

159 uperoxide scavenging was sufficient to block nuclear accumulation of HIF2alpha in RCC cells.

160 Single-cell analysis revealed that nuclear accumulation of HIF2alpha was inhibited in hCMV-

161 langiectasia mutated (ATM) deficiency causes nuclear accumulation of histone deacetylase 4 (HDAC4) in

162 We previously found that nuclear accumulation of histone deacetylase-4, HDAC4, co

163 Furthermore, preventing the nuclear accumulation of Hog1 had no impact on C. albican

164 e expression, and reveal that stress-induced nuclear accumulation of Hog1 is dispensable for the viru

165 n of any of the conserved residues increases nuclear accumulation of Htt exon 1.

166 In addition, proteasome inhibition induces a nuclear accumulation of IkappaB kinase (IKK)alpha, and i

167 responsible mechanism involves an increased nuclear accumulation of IkappaB kinase beta (IKKbeta) an

168 R3 Tyr-759 phosphorylation and decreased the nuclear accumulation of interferon regulatory factors 3

169 fusion of viral and endosomal membranes, and nuclear accumulation of IRF3 and viral NP occurred concu

170 A-elicited TLR3 Tyr-759 phosphorylation, the nuclear accumulation of IRF3/IRF7, and IFN-beta generati

171 plateauing, and paired tumor biopsies showed nuclear accumulation of key tumor-suppressor proteins, r

172 , Ccl19/Ccr7 signaling reduces the level and nuclear accumulation of maternal beta-catenin and its ax

173 nd in therapy-resistant melanoma cell lines, nuclear accumulation of MDM2 caused downregulation of FB

174 cription but inhibited actin polymerization, nuclear accumulation of megakaryoblastic leukemia-1 prot

175 lethality of Tgfb1(-/-) embryos and enhances nuclear accumulation of mothers against decapentaplegic

176 d that finerenone delays aldosterone-induced nuclear accumulation of MR more efficiently than spirono

177 ology, abnormal localization of RanGAP1, and nuclear accumulation of mRNA were found in cortex of Hun

178 These include the nuclear accumulation of mRNAs encoding components of the

179 CD44 RNAi promoted nuclear accumulation of MRTF and the binding to its tran

180 F-A and that CCTepsilon is able to alter the nuclear accumulation of MRTF-A after stimulation by seru

181 ormal lung fibroblasts that PGE2 reduced the nuclear accumulation of MRTF-A.SRF complexes and consequ

182 ng and disassembly of cell contacts leads to nuclear accumulation of MRTFs and the activation of the

183 Nuclear accumulation of mutant huntingtin is a hallmark

184 be a critical age-onset stress that triggers nuclear accumulation of mutant huntington in Huntington'

185 anoma-associated CDKN2A mutation, leading to nuclear accumulation of mutant p16ink4a.

186 vascular endothelial growth factor A induces nuclear accumulation of myocardin-related transcription

187 Furthermore, nuclear accumulation of myocardin-related transcription

188 the distribution of neuropil aggregates and nuclear accumulation of N-terminal mutant huntingtin in

189 tion upon gemcitabine treatment precedes the nuclear accumulation of NF-kappaB and HIF-1alpha, and su

190 transcripts and resulted in rapid (<30 min) nuclear accumulation of NF-kappaB and TRIM21 and ehrlich

191 However, nuclear accumulation of NF-kappaB p65 was not observed i

192 Interestingly, our data demonstrate that nuclear accumulation of NF-kappaB results from phosphory

193 ion in miR-301a-inhibited condition restores nuclear accumulation of NF-kappaB to a basal level.

194 Nuclear accumulation of NFAT was highly dependent on sus

195 somal kinase, pERK1/2, pAKT, pGSK-3beta, and nuclear accumulation of NFAT.

196 ated T cells, cytoplasmic 1 (Nfatc1) and the nuclear accumulation of NFATc1, a master regulator of os

197 ), including p38 MAPKs and ERKs, followed by nuclear accumulation of Nrf2 and downregulation of Keap1

198 cells with sulforaphane (2.5 mum) increased nuclear accumulation of Nrf2 over 1-4 h.

199 er (UCB), silencing of GULP1 facilitated the nuclear accumulation of NRF2, led to constitutive activa

200 In turn, PKR stimulates nuclear accumulation of nuclear factor kappaB (NF-kappaB

201 In AA prostate cancer cells, decreased nuclear accumulation of nuclear respiration factor 1 (Nr

202 ion of STAT3 over AKT1 and ERK1/2 (MAPK3/1), nuclear accumulation of P-Y705-STAT3, STAT3-DNA binding,

203 human colonic carcinoma cells with ST led to nuclear accumulation of p21, resulting in cellular senes

204 umor-derived prostaglandin E2 (PGE2) induces nuclear accumulation of p50 NF-kappaB in M-MDSCs, divert

205 lear export protein exportin 1 (XPO1) causes nuclear accumulation of p53 and disruption of NF-kappaB

206 ued G(1) arrest, Ser-33 phosphorylation, and nuclear accumulation of p53 induced by SEPW1 depletion,

207 In contrast, nuclear accumulation of p57kip2 resulted in blocked olig

208 utation in human A549 cells showed increased nuclear accumulation of PA and increased viral polymeras

209 of PA-X was also accompanied by accelerated nuclear accumulation of PA protein and reduced suppressi

210 activates its poly(A)RNA binding, leading to nuclear accumulation of PABP1 and poly(A)RNA and thus fa

211 ndent phosphorylation of TIM(S1404) promotes nuclear accumulation of PER-TIM heterodimers by inhibiti

212 Forced nuclear accumulation of PHB1 in human RKO or SW48 CRC ce

213 nhibitors FK506 or cyclosporin A resulted in nuclear accumulation of phospho-HDAC1 and was neuroprote

214 aling, indicated by increased expression and nuclear accumulation of phospho-RelA/p65, occurred in bo

215 Decreased shuttling limits nuclear accumulation of phosphorylated (activated) SRY,

216 c activation of Ras was sufficient to induce nuclear accumulation of phosphorylated MEK1/2 and ERK1/2

217 Nuclear accumulation of phosphorylated Smad1, a primary

218 F-beta in PKD is not clearly understood, but nuclear accumulation of phosphorylated SMAD2/3 in cyst-l

219 that tyrosine kinase inhibitors can inhibit nuclear accumulation of PKCdelta.

220 Here, we show that fibroblasts diminish nuclear accumulation of platinum in ovarian cancer cells

221 xposure of human HaCaT keratinocytes induced nuclear accumulation of PRMT1 and PRMT4, histone H4R3 an

222 a rare, accelerated aging disorder caused by nuclear accumulation of progerin, an altered form of the

223 to shrink during metamorphosis, followed by nuclear accumulation of Prospero and cell cycle exit.

224 This work helps explain the nuclear accumulation of PTEN observed in many healthy ti

225 Both proteins control the nuclear accumulation of Rgf1p by inhibition of its nucle

226 However, the mechanisms that permit nuclear accumulation of RSK1 remain unknown.

227 its XPO1-mediated nuclear export, leading to nuclear accumulation of RSV M protein and reduction in R

228 her, these findings challenge the dogma that nuclear accumulation of SAPKs is a pre-requisite for SAP

229 We previously observed nuclear accumulation of Ser-552 phosphorylated beta-cate

230 ticulum, less efficient virion secretion and nuclear accumulation of significantly higher amounts of

231 ventually leading to the high expression and nuclear accumulation of Snail and beta-catenin, which fa

232 le1 nucleocytoplasmic shuttling, we detected nuclear accumulation of specific mRNAs with elongated 3'

233 IRS1KOs exhibited low nuclear accumulation of spliced XBP-1 due to its poor st

234 1 is not only positively correlated with the nuclear accumulation of SREBP1 in samples from patients

235 adjacent to a nuclear export signal prevents nuclear accumulation of Stu2 before cells enter mitosis.

236 0007) correlation between IDH1 mutations and nuclear accumulation of TET1, but not with loss of 5hmC.

237 oting cytoplasmic localization, resulting in nuclear accumulation of the clipped protein.

238 In contrast, SUMOylation was required for nuclear accumulation of the ErbB4 ICD.

239 TORC2 is essential for proper expression and nuclear accumulation of the GFAT1 transcriptional regula

240 Furthermore, RASSF1A reduced nuclear accumulation of the Hippo pathway transcriptiona

241 Most phyA responses require nuclear accumulation of the photoreceptor, but interesti

242 Androgen-dependent nuclear accumulation of the polyglutamine-expanded AR is

243 observed overexpression and increased intra-nuclear accumulation of the PRMT5/WDR77 in breast cancer

244 hat decreased p27(kip1) levels and prevented nuclear accumulation of the proapoptotic factor apoptosi

245 Rigid matrix is needed to induce rapid nuclear accumulation of the RARG isoform and for RARG-sp

246 Nuclear accumulation of the small phosphoprotein integri

247 degradation in the cytoplasm, thus reducing nuclear accumulation of the transcription factor in the

248 driven and mechanistically dependent on the nuclear accumulation of the transcription factor NF-kapp

249 hway restricts cellular growth by preventing nuclear accumulation of the Yes-associated protein (YAP)

250 n fused to green fluorescent protein, led to nuclear accumulation of this chimeric protein, indicatin

251 ls expressing the mutant Ku are deficient in nuclear accumulation of TLC1, as expected from the RNA-b

252 d to form proper nuclear pores, leading to a nuclear accumulation of total mRNA and abnormal activati

253 F6 and c-SRC into lipid rafts and preventing nuclear accumulation of transcriptional activator NFATc1

254 interaction and enhanced ATF6 processing and nuclear accumulation of transcriptionally active ATF6, i

255 ronises the circadian clock: cooling induces nuclear accumulation of transcripts that encode negative

256 NAs tested, silencing of TbMex67, led to the nuclear accumulation of tRNAs that are typically modifie

257 charide-(LPS)-cell stimulation, which causes nuclear accumulation of TRX-1 and enhanced transcription

258 In fact, TrxR-1 inhibition prevents nuclear accumulation of TRX-1 and LPS-stimulated hyperpr

259 blocks exportin 1 (XPO1) function, leads to nuclear accumulation of tumor suppressor proteins, and i

260 of paired tumor biopsies revealed increased nuclear accumulation of tumor suppressor proteins, decre

261 ntified SINEs that inhibit CRM-1 and promote nuclear accumulation of tumor-suppressor proteins in pan

262 UV-B photoreception stimulates nuclear accumulation of UVR8 in a presently unknown mann

263 OGENIC 1 (COP1) is required for UV-B-induced nuclear accumulation of UVR8, but bypassing the COP1 req

264 nvironment by inducing hypoxia increases the nuclear accumulation of villin.

265 e postentry step of infection to prevent the nuclear accumulation of viral cDNA.

266 rus type 1 (HIV-1) infection, inhibiting the nuclear accumulation of viral cDNAs.

267 hat antibodies to hsc70 significantly reduce nuclear accumulation of wild type SRY and mutant derivat

268 Nuclear accumulation of WWOX is regulated by its K63-lin

269 he deubiquitination, increased stability and nuclear accumulation of XBP1s protein.

270 aluronan caused nuclear depletion of FRMD4A, nuclear accumulation of YAP and reduced SCC growth and m

271 c-like stemness of PGCCs was associated with nuclear accumulation of YAP, a key mediator of the Hippo

272 at radiation-induced CS-GRP78 stimulates the nuclear accumulation of YAP/TAZ and increases YAP/TAZ ta

273 embers mutations were associated with higher nuclear accumulation of YAP/TAZ, core effectors of the H

274 n cancers strongly correlated with increased nuclear accumulation of Yap1, indicating that the effect

275 nhibits Hippo signaling, leading to enhanced nuclear accumulation of YAP1, which interacted with and

276 h uncoupled Mst1/2 from Lats1/2 and promoted nuclear accumulation of Yap1.

277 and p38 MAPK-dependent cascade that leads to nuclear accumulation of Yes-associated protein (YAP) and

278 large tumor suppressor kinase-1 and reduces nuclear accumulation of yes-associated protein and its t

279 tment of RCC cells did not impair HIF-1alpha nuclear accumulation or transcriptional activity, and ha

280 n C-terminal module and PIF3, abrogates PHYB nuclear accumulation, photobody biogenesis, and PIF3 deg

281 1 transcriptional activation showed that the nuclear accumulation rate of change of the signaling fac

282 v-Src, and Src kinase induction of Trop2 ICD nuclear accumulation required cyclin D1.

283 FAK, Src, PI3K, or PDK1 activity blocked YAP nuclear accumulation stimulated by adhesion to fibronect

284 TGF-beta induced Olfm2 nuclear accumulation, suggesting that Olfm2 may be invol

285 ylation activates the SAPK, and promotes its nuclear accumulation that is necessary for the expressio

286 Moreover, DeltaNp63alpha promotes YB-1 nuclear accumulation thereby reducing the amount of YB-1

287 hibits LPS-induced STAT5 phosphorylation and nuclear accumulation, thereby attenuating its transcript

288 We isolated acinar cells and measured NFAT nuclear accumulation, trypsin activity, and expression o

289 nt nuclear import, with an increased rate of nuclear accumulation upon addition of both CaM and hsc70

290 ut not poly-d-lysine or laminin, induced YAP nuclear accumulation via the FAK-Src-phosphatidylinosito

291 al mutations in SRY that specifically impair nuclear accumulation via this pathway resulting in XY se

292 d nuclear factor of activated T cells (NFAT) nuclear accumulation was abrogated by either antioxidant

293 aemia, increased beta-catenin signalling and nuclear accumulation was identified in osteoblasts and t

294 ever, the genetic mechanisms controlling IYO nuclear accumulation were unknown, and the evidence that

295 AKT inhibition alone maximally induced GAPDH nuclear accumulation, whereas MEK/ERK inhibition alone h

296 up-regulated class I and II HDACs and their nuclear accumulation, whereas PSS (12 +/- 4 dynes/cm(2))

297 Both processes promote beta-catenin nuclear accumulation, which up-regulates epithelial-to-m

298 Mechanistically, SIH did not lead to GRK5 nuclear accumulation, which was confirmed in vitro as in

299 ly increased JunB reporter activity and JunB nuclear accumulation, which were inhibited by the A2B re

300 binding protein calmodulin (CaM) for optimal nuclear accumulation, with clinical mutations in SRY tha