ライフサイエンスコーパス: nuclear export sequence

1 ar 'address' (nuclear localization signal or nuclear export sequence).

2 h was further augmented by removal of FMRP's nuclear export sequence.

3 HDAC4 reversal depended on the HDAC4 nuclear export sequence.

4 hift, unmasking an additional CRM1-dependent nuclear export sequence.

5 ctional HCF-binding motif and a leucine-rich nuclear export sequence.

6 ed mTOR nuclear export with the tagging of a nuclear export sequence.

7 omycin B, despite the absence of a classical nuclear export sequence.

8 of IkappaBalpha is mediated by an N-terminal nuclear export sequence.

9 del for the intermolecular regulation of the nuclear export sequence.

10 -export is attributable to its nonfunctional nuclear-export sequence.

11 RCA1 contains at least two leucine-dependent nuclear export sequences.

12 ts demonstrated that Cdc25 contains multiple nuclear export sequences.

13 at functions as cytoplasmic retention and/or nuclear export sequences.

14 CD8 T cells harboring a mutated IkappaBalpha nuclear export sequence abnormally accumulate inactive c

15 uncated Ssd1 proteins, which presumably lack nuclear export sequences, accumulate in the nucleus.

16 This nuclear export sequence also caused nuclear exclusion of

17 n-dependent kinases to inactivate a dominant nuclear export sequence, also in the LRR.

18 nd COS-7 cells as did deletion of a putative nuclear export sequence (amino acids 224 to 233) or muta

19 accumulation in the nucleus involves both a nuclear export sequence and a nuclear localization signa

20 orted from the nucleus in the absence of its nuclear export sequence and in the presence of a strong

21 is serine lies directly within the cyclin B1 nuclear export sequence and, when phosphorylated, preven

22 inase: a mitochondrial targeting sequence, a nuclear export sequence, and a nuclear localization sequ

23 This residue is nested in a classical nuclear export sequence, and phosphorylated Ser-271 5-LO

24 Additionally, ORF 3b contains a consensus nuclear export sequence, and we demonstrate that nuclear

25 m, using typical hydrophobic amino acid-rich nuclear export sequences, and nuclear localization seque

26 ber of other tumor suppressors have multiple nuclear export sequences, and we sought to determine whe

27 into the cytoplasm requires two leucine-rich nuclear export sequences at the C-terminus.

28 her Ran-guanosine triphosphate (GTP) nor the nuclear export sequence binding site.

29 conserved nuclear localization sequences or nuclear export sequences but can accumulate in the nucle

30 smic localization, is actually an autonomous nuclear export sequence, capable of directing nuclear ex

31 Tagging either Rnr2 or Rnr4 with a nuclear export sequence causes cytoplasmic localization

32 th the addition of a nuclear localization or nuclear export sequence demonstrates that nuclear accumu

33 distinct from the LMB-inhibited leucine-rich nuclear export sequence-dependent CRM1 pathway, which is

34 Pik1(Delta10-192), which lacks its nuclear export sequence, displayed prominent nuclear acc

35 hich connects the second helix of Rev to its nuclear export sequence has structural requirements for

36 ion of BRCA1-BARD1 complex and exposure of a nuclear export sequence in BARD1 that is otherwise maske

37 ues 81-99 comprising the previously reported nuclear export sequence in BRCA1.

38 The nuclear export of MPF is mediated by a nuclear export sequence in cyclin B1, and an export-defe

39 oth RGS4 and RGS16, a domain identified as a nuclear export sequence in HIV Rev and other proteins, p

40 wever, the presence of a functional Rev-like nuclear export sequence in hRPF1/Nedd4 ensures a predomi

41 that NPM utilizes a conserved CRM1-dependent nuclear export sequence in its amino terminus to enable

42 show that mutation or deletion of a putative nuclear export sequence in LTV1 is strongly dominant neg

43 , we identified a previously uncharacterized nuclear export sequence in residues 45-54 of IkappaBalph

44 of nuclear export or deletion of a putative nuclear export sequence in the C-terminal tail promotes

45 ctopic expression of Cyclin B1 with a mutant nuclear export sequence induced chromosome condensation,

46 osition 71 between the known RNA-binding and nuclear export sequences interfered with GFPRem accumula

47 the nucleus, possibly due to disruption of a nuclear export sequence located downstream of the FERM-a

48 We show that c-Rel lacks a nuclear export sequence, making the removal of c-Rel-con

49 These novel nuclear export sequences may provide additional routes f

50 functional nuclear localization sequence and nuclear export sequence motifs in ILK, delineated an app

51 Moreover, this nuclear export sequence mutant [NES(-) Crk] interacts st

52 ific function dictated by its amino-terminal nuclear export sequence (N-NES).

53 However, the identity of the nuclear export sequences NES(s) in IkappaBalpha that are

54 RAK shows that PRAK contains both a putative nuclear export sequence (NES) and a nuclear localization

55 DAC4 and -5 each contain a signal-responsive nuclear export sequence (NES) at their extreme carboxy t

56 717-724 that bears strong homology to known nuclear export sequence (NES) domains.

57 that the dsRBD of ILF3 functions as a novel nuclear export sequence (NES) in intact cells, and its a

58 ion repressor of Nrf2 and demonstrate that a nuclear export sequence (NES) in Keap1 is required for t

59 as a leptomycin B-sensitive, CRM1-dependent nuclear export sequence (NES) in the AMPK catalytic subu

60 nd that DHOV M interacts with CRM1 through a nuclear export sequence (NES) located between amino acid

61 tative nuclear localization signal (NLS) and nuclear export sequence (NES) of FAC1, using deletion mu

62 L505R (LR) and R507Q (RQ) located within the nuclear export sequence (NES) of human RGS14.

63 The N-terminal nuclear export sequence (NES) of inhibitor of nuclear fa

64 t is required for functional activity of the nuclear export sequence (NES) of p53.

65 cts of RXRalpha are attributed to a putative nuclear export sequence (NES) present in its carboxyl-te

66 Recently, we identified a specific nuclear export sequence (NES) required to maintain CMK-1

67 st Gle1p, a protein with a leucine-rich (LR) nuclear export sequence (NES) that is essential for poly

68 We have determined that N17 acts as a nuclear export sequence (NES) within Htt exon and when f

69 s identified in ICP27 include a leucine-rich nuclear export sequence (NES), a nuclear localization si

70 n of these cells, we found that a functional nuclear export sequence (NES), ATP, and fractionated cyt

71 rved nuclear localisation sequence (NLS) and nuclear export sequence (NES), suggesting a role in nucl

72 ation which contains a dominant leucine-rich nuclear export sequence (NES), the previously defined cy

73 actors interacting with the Rev leucine-rich nuclear export sequence (NES), we identified a kinesin-l

74 Bepsilon is mediated by a short leucine-rich nuclear export sequence (NES)-like sequence ((343)VLLPFD

75 clear in a crm1 mutant, and Crm1p binds to a nuclear export sequence (NES)-like sequence in Yap1p in

76 d amino acids within N17 that constitute the nuclear export sequence (NES).

77 N-terminal region that includes a potential nuclear export sequence (NES).

78 ich has been shown to require a leucine-rich nuclear export sequence (NES).

79 xport of Upf3p is mediated by a leucine-rich nuclear export sequence (NES-A), but export is not depen

80 ize nuclear localization sequences (NLSs) or nuclear export sequences (NESs) and target the NLS-beari

81 e RRE assembles a Rev oligomer that displays nuclear export sequences (NESs) for recognition by the C

82 In addition, two nuclear export sequences (NESs) within the NTF2-like reg

83 Interestingly, the nuclear export sequence of IkappaB-alpha was not require

84 Mutations in the nuclear export sequence or dimerization interface render

85 Cdc25, allowing nuclear export mediated by a nuclear export sequence present in the N-terminus of Cdc

86 ility of hydrophobic residues (including the nuclear export sequence), providing a rationale for the

87 Our data showed that a nuclear export sequence resides within a 70-amino acid d

88 A cyclin D1 mutation in its nuclear export sequence (T286A) partially rescued nuclea

89 Although nuclear localization sequence- and nuclear export sequence-targeted proteins both activated

90 Here, we report that BRCA1 contains a second nuclear export sequence that comprises amino acid residu

91 A nuclear export sequence that is embedded in the dimeriza

92 RM1, through a specific leucine-rich domain (nuclear export sequence) that regulates its export to th

93 Several candidate nuclear export sequences were also found in CIITA and on

94 xport of a protein containing a leucine-rich nuclear export sequence, whereas nuclear import of a pro

95 This work defines a bona fide nuclear export sequence within N17 and links it to effec

96 ional nuclear localization signals (NLS) and nuclear export sequences, yet nuclear import depended on