ライフサイエンスコーパス: nuclear hormone receptor

1 thesis of ligands that inhibit the DAF-12, a nuclear hormone receptor.

2 oform a, suggesting an anabolic role for the nuclear hormone receptor.

3 s transcription by thyroid hormone and other nuclear hormone receptors.

4 e largely been credited to the activation of nuclear hormone receptors.

5 actor Nur77 belongs to the NR4A subfamily of nuclear hormone receptors.

6 juba as a unique corepressor for a subset of nuclear hormone receptors.

7 esylation, can act as an agonist for several nuclear hormone receptors.

8 aracteristic of coactivators/corepressors of nuclear hormone receptors.

9 ax lethal toxin (LeTx) selectively represses nuclear hormone receptors.

10 tional repression complexes recruited by the nuclear hormone receptors.

11 ation by SHP is dependent on the presence of nuclear hormone receptors.

12 with inactivation of repression mediated by nuclear hormone receptors.

13 gand-dependent transcriptional activation by nuclear hormone receptors.

14 t suggests a new paradigm for this family of nuclear hormone receptors.

15 ds to and influences the activity of several nuclear hormone receptors.

16 se in O-GlcNAc levels inhibits activation of nuclear hormone receptors.

17 re members of the family of ligand-dependent nuclear hormone receptors.

18 g delivery to tumor cells with overexpressed nuclear hormone receptors.

19 also shed light on the natural evolution of nuclear hormone receptors.

20 LBPs is to deliver small-molecule ligands to nuclear hormone receptors.

21 the clinical efficacy of agents that target nuclear hormone receptors.

22 led an evolutionarily conserved template for nuclear hormone receptors.

23 homeostatic processes that are controlled by nuclear hormone receptors.

24 Pase 12 (vha-12) and its upstream regulator, nuclear hormone receptor 31 (nhr-31), abolished the resc

25 ceptors (RXRs) are important transcriptional nuclear hormone receptors, acting as either homodimers o

26 dynamics that drive this unusual PL-mediated nuclear hormone receptor activation.

27 been reported to be involved in influencing nuclear hormone receptor activities.

28 and HEXIM1 is required for the inhibition of nuclear hormone receptor activity by KDM5B.

29 breast cancer cells with probe 4 attenuates nuclear hormone receptor activity mediated by retinoic a

30 ponent of the Mediator complex that controls nuclear hormone receptor activity, are repressed by miR-

31 he diversification of binding motifs for the nuclear hormone receptor and C2H2 zinc finger families a

32 rkers of the basal-like phenotype, including nuclear hormone receptor and HER2 negativity, cytokerati

33 These results indicate a link between nuclear hormone receptor and insulin signaling pathways,

34 The androgen receptor (AR) is a type I nuclear hormone receptor and the primary drug target in

35 r gamma (PPARgamma) belongs to the family of nuclear hormone receptors and consists of two isotypes,

36 d prevents these fatty acids from activating nuclear hormone receptors and driving fat-7 expression.

37 ted the binding of 75 TFs, including several nuclear hormone receptors and ETS factors, to the highly

38 s (PPARs) (alpha, gamma, and delta/beta) are nuclear hormone receptors and ligand-activated transcrip

39 ctivator is a property shared with mammalian nuclear hormone receptors and likely allows greater tran

40 st metabolic genes via its interactions with nuclear hormone receptors and nuclear respiratory factor

41 Mediator (MED) facilitates transcription of nuclear hormone receptors and other transcription factor

42 r (NRC) is a 2,063-amino-acid coregulator of nuclear hormone receptors and other transcription factor

43 ochondrial biogenesis through stimulation of nuclear hormone receptors and other transcription factor

44 of TRAP/Mediator that targets the complex to nuclear hormone receptors and other types of activators.

45 of 0.7 nM with great selectivity over other nuclear hormone receptors and potently activated AR in a

46 we show that the direct interaction between nuclear hormone receptors and Prox1 is also necessary fo

47 s that logically explain the coordination of nuclear hormone receptors and the clock are poorly under

48 role of mammalian hADA3 as a coactivator of nuclear hormone receptors and the potential role of thes

49 nalysis will stimulate further research into nuclear hormone receptors and their associated transcrip

50 region in the ZnF_C4 signature motif of the nuclear hormone receptors and thus against the entire re

51 ative lipophilic hormone receptors, known as nuclear hormone receptors, and analyzed their functions

52 of drug targets (receptor tyrosine kinases, nuclear hormone receptors, and cytoplasmic protein kinas

53 mplex relationships among the immune system, nuclear hormone receptors, and inflammation during regre

54 uch an analysis has been carried out for the nuclear hormone receptors, and the conclusions tested by

55 Mechanisms controlling nuclear hormone receptors are a central question to mamm

56 ligand-regulated transcription factors, the nuclear hormone receptors are nearly ideal drug targets,

57 ole in mediating the effects of ligand-bound nuclear hormone receptors as well as other transcription

58 ies of transcriptional regulators, including nuclear hormone receptors, basic helix-loop-helix, ETS-

59 arly perfect direct repeats of the consensus nuclear hormone receptor binding element AGGTCA separate

60 PGC-1alpha differ in their interactions with nuclear hormone receptors but are highly similar in thei

61 essors contributes to specific regulation of nuclear hormone receptors by O-GlcNAc.

62 transcriptional efficacy of ligand activated nuclear hormone receptors by up to 8-fold in vitro and i

63 17 cell markers retinoic acid-related orphan nuclear hormone receptor c (RORc), IL-17A, and IL-23R.

64 pression of the retinoic acid-related orphan nuclear hormone receptor C and IL-17A and secretion of I

65 e inhibition of retinoic acid-related orphan nuclear hormone receptor C and IL-17A gene expression an

66 e expression of retinoic acid-related orphan nuclear hormone receptor C, a transcription factor that

67 g, in part through the local availability of nuclear hormone receptors called retinoic acid receptors

68 hat MED1 phosphorylation is required for its nuclear hormone receptor coactivator activity.

69 usly been demonstrated to associate with the nuclear hormone receptor coactivator AIB1/SRC-3, the que

70 The nuclear hormone receptor coactivator PGC-1 (peroxisome p

71 3 (SRC-3) is a histone acetyltransferase and nuclear hormone receptor coactivator, located on 20q12,

72 60 coregulators were initially identified as nuclear hormone receptor coactivators.

73 We demonstrate that dUTX binds to the nuclear hormone receptor complex Ecdysone Receptor/Ultra

74 ic Ecdysone receptor/Ultraspiracle (ECR/USP) nuclear hormone receptor complex throughout the entire n

75 significantly, the footprint sequences bind nuclear hormone receptor complexes in male, but not fema

76 ata are consistent with the possibility that nuclear hormone receptor complexes participate in the es

77 The nuclear hormone receptors comprise one of the largest cl

78 Nuclear hormone receptor coregulator (NRC) is a 2,063-am

79 ression of friend of GATA (FOG)-2, a cardiac nuclear hormone receptor corepressor protein.

80 Here we demonstrate that the nuclear hormone receptor Coup-TFII is necessary for the

81 We examined the role of the orphan nuclear hormone receptor CoupTFI in mediating cortical d

82 the FOXO transcription factor DAF-16 and the nuclear hormone receptor DAF-12 and influences metabolic

83 We show that the nuclear hormone receptor daf-12 is a let-7 target in sea

84 l timing and longevity through the conserved nuclear hormone receptor DAF-12, a homolog of mammalian

85 lifespan of C. elegans are controlled by the nuclear hormone receptor DAF-12, an important model for

86 gulating the transcriptional activity of the nuclear hormone receptor DAF-12.

87 lic hormone, which serves as a ligand to the nuclear hormone receptor DAF-12.

88 A nuclear hormone receptor, daf-12, previously implicated

89 developmental trajectories interact with the nuclear hormone receptor, DAF-12, to initiate and regula

90 The nuclear hormone receptor Dax1 functions during developme

91 We identified a nuclear hormone receptor, DHR96, as an essential mediato

92 cadian and major hormonal circuits involving nuclear hormone receptors display interlinked diurnal cy

93 s known about the expression of TRs or other nuclear hormone receptors during the cell cycle.

94 XA7 promoter identified a cluster of steroid nuclear hormone receptor elements, including V$GREF (V$G

95 lk" between a membrane receptor (CD44) and a nuclear hormone receptor (ER alpha) signaling pathway du

96 nhr-23 and nhr-25, genes encoding conserved nuclear hormone receptors essential for larval molting.

97 The nuclear hormone receptor estrogen receptor alpha (ERalph

98 We identified the orphan nuclear hormone receptor estrogen-related receptor beta

99 The nuclear hormone receptor, estrogen receptor alpha (ERalp

100 interact with the androgen receptor (AR), a nuclear hormone receptor expressed at high levels in Ser

101 ted basal-like differentiation and repressed nuclear hormone receptor expression after short-term PTE

102 d entry mechanism for members of the steroid nuclear hormone receptor family (androgen receptor, estr

103 oic acid receptors (RARs) are members of the nuclear hormone receptor family and regulate the prolife

104 d receptors (PPARs) and other members of the nuclear hormone receptor family are important drug targe

105 he androgen receptor (AR) is a member of the nuclear hormone receptor family of transcription factors

106 he androgen receptor (AR) is a member of the nuclear hormone receptor family of transcription factors

107 ERBalpha (encoded by Nr1d1), a member of the nuclear hormone receptor family, as a transcriptional re

108 receptor-gamma (PPARgamma), a member of the nuclear hormone receptor family, is a master regulator o

109 tivated receptors (PPARs) are members of the nuclear hormone receptor family, playing pivotal roles i

110 farnesoid X receptor (FXR), a member of the nuclear hormone receptor family, plays important roles i

111 receptor gamma (PPARgamma), a member of the nuclear hormone receptor family, represents a possible n

112 n bisphenols and ERs or other members of the nuclear hormone receptor family, such as estrogen-relate

113 rogen receptor alpha (ER) is a member of the nuclear hormone receptor family, which upon binding estr

114 ay be easily adapted to other members of the nuclear hormone receptor family.

115 r prior studies with the bile acid-activated nuclear hormone receptor farnesoid X receptor (FXR) and

116 Bile acids are ligands for the nuclear hormone receptor farnesoid X receptor (FXR) and

117 Bile acids are ligands for the nuclear hormone receptor, farnesoid X receptor (FXR).

118 Here, we show that the nuclear hormone receptor for oxysterols, the liver X rec

119 ated three dominant, X-linked mutants in the nuclear hormone receptor gene nhr-40 that are haploinsuf

120 nzalutamide via activation of an alternative nuclear hormone receptor, glucocorticoid receptor (GR),

121 ember of the p160 family of coactivators for nuclear hormone receptors, has been frequently detected

122 Numerous coactivators that bind nuclear hormone receptors have been isolated and charact

123 dermal ontogenesis is poorly understood, but nuclear hormone receptors have been shown to have an imp

124 Loss of the nuclear hormone receptor hepatocyte nuclear factor 4alph

125 The nuclear hormone receptors hepatocyte nuclear factor 4 (H

126 five footprinted areas contains at least two nuclear hormone receptor hexad binding sites arranged wi

127 d oxidation through its association with the nuclear hormone receptors HNF-4 and PPAR-alpha, respecti

128 expressed from lentiviruses and (3) that the nuclear hormone receptor HNF4A is essential for specific

129 We find that the SF1-related Drosophila nuclear hormone receptor HR39 is also essential for sexu

130 The NR5A-class nuclear hormone receptor Hr39 is essential for precursor

131 down expression after adult eclosion of the nuclear hormone receptor Hr39, a master regulator of gla

132 ell-described cotranscriptional activator of nuclear hormone receptors (i.e., Sp1), the hypothesis th

133 previously unrecognized role for this orphan nuclear hormone receptor in regulating STAT1 signaling a

134 s requires understanding the pivotal role of nuclear hormone receptors in lipid and inflammatory home

135 o explore the roles of dynamically expressed nuclear hormone receptors in molting, and to analyze mei

136 Our studies identify a role for nuclear hormone receptors in planarian reproductive matu

137 to potentiate transcriptional activation by nuclear hormone receptors in podocytes.

138 uggest a potential role for dysregulation of nuclear hormone receptors in the pathogenesis of ADPKD.

139 tion studies, and elucidation of the role of nuclear hormone receptors in the regulation of bile salt

140 amined the expression patterns of a panel of nuclear hormone receptors in these two cell lines and de

141 The superfamily of nuclear hormone receptors includes transcription factors

142 (also known as GPBAR1, M-BAR, and BG37) and nuclear hormone receptors including farnesoid X receptor

143 le cross-reactivity against a panel of human nuclear hormone receptors including PPARdelta.

144 ember of the p160 family of coactivators for nuclear hormone receptors including the androgen recepto

145 ow-density lipoprotein receptor (LOX-1); the nuclear hormone receptors, including peroxisome-prolifer

146 are not available to cell surface receptors, nuclear hormone receptors, ion channels, transporters, a

147 Liver X receptor (LXR), a nuclear hormone receptor, is an essential regulator of i

148 dogenic factor SF-1, a constitutively active nuclear hormone receptor, is essential to the developmen

149 factor 4alpha (HNF4alpha), a liver-enriched nuclear hormone receptor, is markedly inhibited, whereas

150 though NIF-1 does not directly interact with nuclear hormone receptors, it enhances activation by nuc

151 binding site in the AKR1C4 promoter for the nuclear hormone receptor known as liver X receptor alpha

152 Small heterodimer partner (SHP), an orphan nuclear hormone receptor lacking a DNA binding domain, i

153 The two nuclear hormone receptor ligands progesterone and vitami

154 The nuclear hormone receptor liver X receptor (LXR) is induc

155 Previously, we have shown that the nuclear hormone receptor liver X receptor-alpha (LXRalph

156 The nuclear hormone receptors liver X receptor alpha (LXRalp

157 r of metabolism and inflammation, the orphan nuclear hormone receptor, liver receptor homolog-1 (LRH-

158 nd genetic evidence establishing the liver-X nuclear hormone receptor (LXR) as a therapeutic target i

159 thesis in HepG2 cells suggests that multiple nuclear hormone receptors mediate viral replication in t

160 tion of the androgen receptor (AR) and other nuclear hormone receptor-mediated actions.

161 the development of BPA substitutes devoid of nuclear hormone receptor-mediated activity and more gene

162 raction identifies a site of convergence for nuclear hormone receptor-mediated and VSMC-specific gene

163 s Jmjd1a and Kdm3a) has an important role in nuclear hormone receptor-mediated gene activation and ma

164 eptor lacking a DNA binding domain, inhibits nuclear hormone receptor-mediated viral transcription an

165 soid X receptor (FXR), a bile acid-activated nuclear hormone receptor, modulates renal SREBP-1 expres

166 One of these proteins, the DAF-12 nuclear hormone receptor, modulates the transcription of

167 xpression during molting, likely through the nuclear hormone receptor NHR-23.

168 The Caenorhabditis elegans Nuclear Hormone Receptor NHR-49 coordinates expression o

169 occurs with precise timing, and requires the nuclear hormone receptor NHR-67.

170 , which promoted longevity by activating the nuclear hormone receptors NHR-49 and NHR-80.

171 thway, the abnormal DAuer Formation (DAF) 12 nuclear hormone receptor (NHR) pathway, functions cell-i

172 lapping feedback loops that are modulated by nuclear hormone receptors (NHR), miRNAs, and epigenetic

173 er in controlling gene regulation in nature, nuclear hormone receptors (NHRs) have largely eluded uti

174 Nuclear hormone receptors (NHRs) regulate the expression

175 ted ion channels and, in a recent update, 49 nuclear hormone receptors (NHRs).

176 )) that solely disrupts its interaction with nuclear hormone receptors (NHRs).

177 ID) for detecting ligands that interact with nuclear hormone receptors (NHRs).

178 d hormone receptors (TRs) are members of the nuclear hormone receptor (NR) superfamily and regulate d

179 by inactivation of a photoreceptor-specific nuclear hormone receptor, NR2E3.

180 Nuclear hormone receptors (NRs) are major targets for ph

181 Certain nuclear hormone receptors (NRs) play a pivotal role in l

182 Nuclear hormone receptors (NRs) regulate physiology by s

183 d on G protein-coupled receptors (GPCRs) and nuclear hormone receptors (NRs), respectively.

184 an acetyl-CoA carboxylase (ACC) and certain nuclear hormone receptors (NRs).

185 The orphan nuclear hormone receptor, nuclear receptor subfamily 4,

186 Nuclear hormone receptors of the NR4A subgroup have been

187 Synthetic peptides that specifically bind nuclear hormone receptors offer an alternative approach

188 Pathway analyses implicated nuclear hormone receptors, particularly retinoic acid an

189 vestigated the possibility that the GATA and nuclear hormone receptor pathways are functionally linke

190 One of these pathways - that of the nuclear hormone receptor peroxisome proliferator activat

191 The nuclear hormone receptor peroxisome proliferator-activat

192 The nuclear hormone receptor peroxisome proliferator-activat

193 The nuclear hormone receptor peroxisome proliferator-activat

194 Activation of the nuclear hormone receptor peroxisome proliferator-activat

195 The nuclear hormone receptor peroxisome proliferator-activat

196 The nuclear hormone receptor peroxisome proliferator-activat

197 The nuclear hormone receptor peroxisome proliferator-activat

198 tion (mediated by CDK9), and activity of the nuclear hormone receptor peroxisome proliferator-activat

199 responses, we examined the expression of the nuclear hormone receptor peroxisome proliferator-activat

200 nosa (PAO1) is enhanced by activation of the nuclear hormone receptor peroxisome proliferator-activat

201 We investigated whether the nuclear hormone receptor peroxisome proliferator-activat

202 -inflammatory actions both by activating the nuclear hormone receptor peroxisome proliferator-activat

203 ized low-density lipoprotein receptor-1, the nuclear hormone receptors peroxisome proliferator-activa

204 of CML through their ability to activate the nuclear hormone receptor, peroxisome proliferator activa

205 The nuclear hormone receptor, peroxisome proliferator-activa

206 thyl ascochlorin (AS-6) is an agonist of the nuclear hormone receptor PPARgamma and has been shown to

207 pase D2 (PLD2) and binds to and inhibits the nuclear hormone receptor PPARgamma with nanomolar affini

208 G-protein-coupled receptors (GPCRs) and the nuclear hormone receptor PPARgamma.

209 This nuclear hormone receptor (PPARgamma) regulates glucose h

210 hormone receptors, it enhances activation by nuclear hormone receptors presumably through its interac

211 iferator-activated receptor (PPAR)gamma is a nuclear hormone receptor primarily characterized for its

212 Conserved nuclear hormone receptors promote expression of the mlt-

213 Two new nuclear hormone receptors, PXR and SXR, have been identi

214 ism regulated by DNA demethylation-dependent nuclear hormone receptor recruitment.

215 Nuclear hormone receptors regulate diverse metabolic pat

216 The difficulty in identifying ligands for nuclear hormone receptors remains an obstacle to underst

217 which encode a cytochrome P450 enzyme and a nuclear hormone receptor, respectively.

218 dden Markov model for predictive modeling of nuclear hormone receptor response elements coupled with

219 ediate transcriptional activation by RA, the nuclear hormone receptor retinoic acid receptor (RAR) an

220 of the transcriptional repressor Id2 and the nuclear hormone receptor retinoic acid-related orphan re

221 In particular, the nuclear hormone receptor retinoic-acid-receptor-related

222 LG100268 (LG268), a synthetic ligand for the nuclear hormone receptor retinoid X receptor, on the exp

223 We screened the nuclear hormone receptor RevErbalpha (Nr1d1), a key cons

224 Their differentiation requires the nuclear hormone receptor RORgammat working with multiple

225 ptional activation cell assays and in silico nuclear hormone receptor screening revealed that certain

226 ents for a series of target families: GPCRs, nuclear hormone receptors, serine proteases, protein kin

227 The orphan nuclear hormone receptor Seven-up (Svp) is necessary and

228 on factor Wt1 to stimulate expression of the nuclear hormone receptor Sf-1 (Nr5a1) in the AGP prior t

229 4,5) triphosphate, a proposed ligand for the nuclear hormone receptor SF-1 (NR5A1).

230 ction cascades (PI3K and MAPK) converging on nuclear hormone receptors (SF-1/LRH-1) to modulate their

231 , we report that an evolutionarily conserved nuclear hormone receptor signaling pathway governs devel

232 ated intersection between these two critical nuclear hormone receptor signaling pathways provides a g

233 ide G-protein-coupled receptors (GPCRs), and nuclear hormone receptors significantly exceed limits fo

234 By screening the human nuclear hormone receptor siRNA library, we identified re

235 The orphan nuclear hormone receptor small heterodimer partner (SHP)

236 We demonstrate that the nuclear hormone receptor ssFTZ-F1 is a key modulator of

237 ortant mediators of CYP3A4 expression is the nuclear hormone receptor, steroid and xenobiotic recepto

238 The vertebrate nuclear hormone receptor steroidogenic factor 1 (SF1; NR

239 hree members of the NR4A1/Nur77/NGFIB orphan nuclear hormone receptor subfamily (NR4A1, NR4A2, and NR

240 r coactivator-1 (SRC-1) is a coactivator for nuclear hormone receptors such as estrogen and progester

241 has been shown to act as a co-activator for nuclear hormone receptors such as estrogen receptor (ER)

242 For example, Hsp90 maintains several nuclear hormone receptors, such as the estrogen receptor

243 seven-transmembrane G-coupled receptors, and nuclear hormone receptors, suggesting that they provide

244 Members of the nuclear hormone receptor superfamily function as key tra

245 Members of the NR4A subgroup of the nuclear hormone receptor superfamily have emerged as key

246 The ER is a member of the nuclear hormone receptor superfamily of transcription fa

247 ted receptor (PPAR)-gamma is a member of the nuclear hormone receptor superfamily that can promote ce

248 farnesoid X receptor (FXR), a member of the nuclear hormone receptor superfamily, and TGR5, a G prot

249 We report here that a member of the nuclear hormone receptor superfamily, chicken ovalbumin

250 the liver X receptor (LXR), a member of the nuclear hormone receptor superfamily, inhibits inflammat

251 r the Liver X Receptor (LXR), members of the nuclear hormone receptor superfamily, prevent the develo

252 or alpha (PPARalpha) is a member of the PPAR nuclear hormone receptor superfamily, which can be activ

253 d X receptor (FXR, NR1H4) is a member of the nuclear hormone receptor superfamily, which plays an ess

254 ligand-activated transcription factor of the nuclear hormone receptor superfamily.

255 and ligand-independent NR4A subfamily of the nuclear hormone receptor superfamily.

256 erved and most ancient NR4A subfamily of the nuclear hormone receptor superfamily.

257 s a ligand-activated transcription factor of nuclear hormone receptor superfamily.

258 arnesoid X receptor (FXR) is a member of the nuclear hormone receptor superfamily.

259 ted transcription factors that belong to the nuclear hormone receptor superfamily.

260 ted receptor (PPAR) delta is a member of the nuclear hormone receptor superfamily.

261 TH receptors (TRs), which are members of the nuclear hormone receptor superfamily.

262 transcription factor that is a member of the nuclear hormone receptor superfamily.

263 en receptor (ER), an important member of the nuclear hormone receptor superfamily.

264 tivated receptors (PPARs) are members of the nuclear hormone receptor superfamily.

265 receptor homolog 1 (LRH-1; NR5A2), an orphan nuclear hormone receptor that controls lipid and glucose

266 Estrogen receptor alpha (ER-alpha) is a nuclear hormone receptor that controls selected genes, t

267 The vitamin D receptor (VDR) is a nuclear hormone receptor that controls transcription of

268 ator-activated receptor gamma (PPARgamma), a nuclear hormone receptor that exhibits wound-healing and

269 or-activated receptor-gamma (PPARgamma) is a nuclear hormone receptor that is critical for adipogenes

270 is elegans, uncoordinated (unc)-55 encodes a nuclear hormone receptor that is necessary for coordinat

271 -regulated genes, including Nr4a1, an orphan nuclear hormone receptor that negatively regulates NF-ka

272 soid X receptor (FXR), a bile acid-activated nuclear hormone receptor that regulates bile acid metabo

273 The vitamin D receptor (VDR) is a nuclear hormone receptor that regulates cell proliferati

274 ceptor homolog 1 (NR5A2, LRH-1) is an orphan nuclear hormone receptor that regulates diverse biologic

275 nist of the farnesoid X receptor, which is a nuclear hormone receptor that regulates glucose and lipi

276 ptor (PXR) and formally known as NR1I2] is a nuclear hormone receptor that regulates inducible metabo

277 patterning requires thyroid hormone beta2, a nuclear hormone receptor that regulates transcription in

278 Rev-erbbeta is a heme-binding nuclear hormone receptor that represses a broad spectrum

279 proliferator-activated receptors (PPARs) are nuclear hormone receptors that act as ligand-activated t

280 tivated receptors (PPARs) are a subfamily of nuclear hormone receptors that function as ligand-activa

281 d gamma (RARalpha, RARbeta and RARgamma) are nuclear hormone receptors that regulate fundamental proc

282 NCOA4 is a transcriptional coactivator of nuclear hormone receptors that undergoes gene rearrangem

283 tional expression of coactivators and of the nuclear hormone receptors themselves.

284 e following pregnancy lack the expression of nuclear hormone receptors, thereby recapitulating many c

285 e ability to interact with and transactivate nuclear hormone receptors through its N-terminal transac

286 unction in the nucleus, including the orphan nuclear hormone receptor TLX.

287 primarily through cognate sterol-responsive nuclear hormone receptors to control these processes thr

288 ific nuclear receptor (PNR/NR2E3), an orphan nuclear hormone receptor, to human breast cancer.

289 motor neurons and, together with the UNC-55 nuclear hormone receptor, to prevent aberrant VD synapti

290 alpha/PPARalpha, plus potentially additional nuclear hormone receptors, to HBV RNA synthesis and repl

291 g the well-established role of the conserved nuclear hormone receptor transcription factor, NHR-23/NR

292 rotein classes (G protein-coupled receptors, nuclear hormone receptors, voltage- and ligand-gated ion

293 nism of ligand dependence is not specific to nuclear hormone receptors, we anticipate that our protei

294 erythroid-derived 2, heat shock factor, and nuclear hormone receptors, which regulate stress-respons

295 ator-activated receptor gamma (PPARgamma), a nuclear hormone receptor with anti-inflammatory effects,

296 ivation of the liver X receptor, LXRalpha, a nuclear hormone receptor with known roles in hepatic lip

297 lting through the ecdysone receptor (EcR), a nuclear hormone receptor with numerous targets including

298 which combine the ligand-binding domains of nuclear hormone receptors with a highly sensitive thymid

299 This approach has been recently expanded to nuclear hormone receptors with the introduction of "phot

300 fold selectivity versus PR and other related nuclear hormone receptors, with improved solubility as c