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1 and correlates with PTEN expression and FOXO nuclear localization.
2 ospho-Ser-127 modification and promotes YAP1 nuclear localization.
3 chloroplast, without any clear evidence for nuclear localization.
4 ing the stability of hDNA2 and promoting its nuclear localization.
5 nd promotes its degradation by promoting its nuclear localization.
6 immune responses is independent of SAMHD1's nuclear localization.
7 ll area, which correlated with decreased YAP nuclear localization.
8 formation, while not affecting beta-catenin nuclear localization.
9 appropriate receptor protein expression and nuclear localization.
10 e Esrp1 peptide that is sufficient to confer nuclear localization.
11 prevented decorin-evoked TFEB induction and nuclear localization.
12 beta-catenin while CHIR99021 increased it in nuclear localization.
13 but one mutant in the cytoplasm, as well as nuclear localization.
14 we confirmed that stauprimide inhibits NME2 nuclear localization.
15 -113 is essential for catalytic activity and nuclear localization.
16 cade to control YAP-S397 phosphorylation and nuclear localization.
17 55 and Baf170 and displayed differential sub-nuclear localization.
18 ased TFEB promoter activity, expression, and nuclear localization.
19 ine residues 421 and 423 as critical for its nuclear localization.
20 ism by which cytoskeletal tension can govern nuclear localization.
21 ignals that regulate ICAP1 and, hence, KRIT1 nuclear localization.
22 motif in ZIKV and DENV NS5 proteins directs nuclear localization.
23 ature shared with HIV in which cPPTs promote nuclear localization.
24 vern Tda1 activity, while CK2 regulates Tda1 nuclear localization.
25 S89, another type I MADS box, which enhances nuclear localization.
26 of nuclease activity, as well as failure of nuclear localization.
27 ted primarily in the nucleus as loss of PTEN nuclear localization abrogated its ability to bind to an
29 associated mutations result in loss of SRCAP nuclear localization, alter neural crest gene programs i
30 cologic inhibition of PKCiota decreases YAP1 nuclear localization and blocks OSC tumor growth in vitr
31 llular delivery sequence induced significant nuclear localization and cell cycle arrest in S phase, a
34 dependent regarding their protein stability, nuclear localization and chromatin recruitment and contr
37 B pathway and consequently reduces NF-kappaB nuclear localization and downregulates NF-kappaB targets
38 box deletion of MAF1 leads to increased MAF1 nuclear localization and enhanced repression of ACC1 and
39 t a SUMOylation-mediated mechanism regulates nuclear localization and function of the ICD of ErbB4 re
41 -binding portal region, abolished both FABP1 nuclear localization and GW7647-induced PPARalpha activa
42 decreases ileal FGF15, enhances hepatic TFEB nuclear localization and improves cholesterol homeostasi
43 associated regulatory beta-subunits restrict nuclear localization and inhibit target gene induction.
44 In HPK1ARas cells, 1alpha,25(OH)2D3-induced nuclear localization and interaction of hRXRalpha are re
45 pr F34I and Q65R viral mutants, we show that nuclear localization and interaction with cullin 4A-DBB1
46 by FGF21 signal-activated PKA increases its nuclear localization and interaction with the nuclear re
47 tance to genotoxic agents by modulating YB-1 nuclear localization and interaction with the splicing f
48 l cells through the inhibition of PGC-1alpha nuclear localization and is also required for angiogenes
49 ndings indicate that androgen regulates YAP1 nuclear localization and its transcriptional activity th
51 SIRT1 at Ser-164 substantially inhibited its nuclear localization and modestly affected its deacetyla
53 he role of individual residues of the NLS in nuclear localization and nucleotide incorporation activi
56 (FABP1), GW7647 treatment increases FABP1's nuclear localization and potentiates GW7647-mediated PPA
57 eus and cytosol, whereas RFA4 shows specific nuclear localization and promotes nuclear degradation of
59 Hippo pathway regulation due to constitutive nuclear localization and resistance to degradation of th
61 did not affect heat-induced oligomerization, nuclear localization and specific DNA binding but inhibi
62 ound that NS5 SIM sites are required for NS5 nuclear localization and that SUMO sites regulate NS5 NB
63 s provide a mechanism for regulation of Bag6 nuclear localization and the functional integrity of the
65 d that ALS-associated Sod1 mutations reduced nuclear localization and, consequently, impaired the ant
66 crophthalmia-associated transcription factor nuclear localization, and Chromatin immuno-Precipitation
67 /Thr-to-alanine variants displayed increased nuclear localization, and NACA dephosphorylation was ass
68 rogates cytoplasmic assemblies, promotes ARF nuclear localization, and results in an altered transcri
69 he transcription factor Yap8, promoting Yap8 nuclear localization, and stimulating the transcription
72 late embryonic periods, and this activity is nuclear localization- and TEAD transcription factor-depe
75 enced by decreased percent androgen receptor nuclear localization (%ARNL) and increased microtubule b
76 romotes EGF-induced EGFR internalization and nuclear localization, associated with induction of EGFR-
77 lls post 24-h serum starvation showed PACS-1 nuclear localization at G(1)-S phase of the cell cycle.
78 mbranous localization, whereas mutant showed nuclear localization; both nuclear and non-nuclear local
79 sponsive transcription factor Crz1 undergoes nuclear localization bursts during the pheromone respons
80 lements that contributed multiplicatively to nuclear localization, but the conserved DNA binding resi
81 transcriptional activation and constitutive nuclear localization, bypassing the need for dimerizatio
83 ions that otherwise modulate PBX1 stability, nuclear localization, DNA binding, and transcriptional a
85 t activation resulted in efficient Set2-LANS nuclear localization followed by H3K36me3 deposition in
86 Furthermore, we show that VOZ TFs require nuclear localization for their contribution to BABA-IR b
87 o our knowledge, this is the first time that nuclear localization has been mapped for any geminiviral
88 though several RNA sequences responsible for nuclear localization have been identified-such as repeat
89 ctional nuclear localization signal and that nuclear localization impairs the ability of ICAP1 to sup
93 n and early tumour initiation and displays a nuclear localization in both mouse and human adenomas.
94 Finally, spliced TERT mRNA had primarily nuclear localization in cancer cells and induced pluripo
95 te Cascade expression, complex formation and nuclear localization in human cells, and demonstrate pro
96 tly, EDP-305 decreased TGF-beta1-induced YAP nuclear localization in human kidney 2 cells by increasi
97 uxin-responsive gene expression and exhibits nuclear localization in regions of high auxin responsive
98 tudies have highlighted the importance of AR nuclear localization in SBMA pathogenesis; therefore, in
101 th the GO-203 inhibitor, which blocks MUC1-C nuclear localization, induced DNA double-strand breaks a
103 a phosphorylation significantly disrupts its nuclear localization, interaction with VDR, intra-nuclea
104 onine and adenine auxotrophy of Ppmet6 Thus, nuclear localization is essential for the stability and
106 y SMAX1 domains that are responsible for its nuclear localization, KAR-induced degradation, associati
109 between the cytoplasm and nucleus due to its nuclear localization (NLS) and export sequences (NES).
110 In this study, we manipulated three putative nuclear localization (NLS1 to -3) and two potential nucl
113 is a broadly expressed nuclear protein, and nuclear localization of AFFL-2 is necessary for its role
118 rturbs pro-cancerous Wnt signaling including nuclear localization of beta-catenin and E-cadherin.
120 ase kinase 3beta (GSK3beta) deactivation and nuclear localization of beta-catenin critical to osteoge
121 tivation triggers Akt signaling and enhances nuclear localization of beta-catenin in osteoblasts.
125 tivated before significant downregulation of nuclear localization of Cic and demonstrated that their
127 ion to this scaffolding role, TRIB1 promotes nuclear localization of COP1 by disrupting an intramolec
130 However, the mechanisms controlling the nuclear localization of FLIL33 or its stability in cells
131 diated by functional activation and enhanced nuclear localization of forkhead box protein O1 transcri
132 ignificantly higher percentage of cells with nuclear localization of gammaH2AX & p16 than non-OSA ind
136 F6-mediated polyubiquitination abolishes the nuclear localization of hDNA2, consequently impairing DN
137 Additionally, in progressing HSK lesions, nuclear localization of HIF-2alpha protein was detected
138 se data suggest that the kinase activity and nuclear localization of HIPK2 are essential for the prod
139 ines concomitantly with increases in piRNAs, nuclear localization of HIWI2 and an increase in H3K9me3
140 response to osmotic stress, and promoted the nuclear localization of Hog1 upon exposure of cells to a
141 Sp1 require the N-terminal pyrin domain and nuclear localization of IFI16, but not the HIN domains i
142 ctate the global genome organization and the nuclear localization of individual chromosomes are not f
143 -like antagonist, INS-37, which promotes the nuclear localization of intestinal HLH-30/TFEB, a key pr
144 rylation of ITCH at Ser257 by AKT led to the nuclear localization of ITCH and ubiquitination of H1.2.
147 se M18BP1/CENP-C interaction cause defective nuclear localization of M18BP1 in interphase, resulting
150 d function primarily inside the nucleus, but nuclear localization of mRNAs has been considered rare i
154 tor of beta-catenin activation, by mediating nuclear localization of NFkappaBp65 and beta-catenin.
155 restingly, cell proliferation, migration and nuclear localization of nuclear factor of activated T-ce
158 quely long half-life and unprecedented basal nuclear localization of p53 in NEFs, naked mole-rat p53
159 atment significantly elevated expression and nuclear localization of PAK4 in correlation with inducti
160 mmunohistochemical analyses showed increased nuclear localization of phosphorylated JUN and SMAD prot
165 at R742A as well as D113R mutations abrogate nuclear localization of PpMS and its ability to reverse
166 croscopy, we confirmed the mitochondrial and nuclear localization of RIbeta in cultured neurons.
168 PV4 activation and volume expansion controls nuclear localization of RUNX2, but not YAP, to promote o
169 However, whether the dNTPase activity and nuclear localization of SAMHD1 are required for its supp
170 we report that the dNTPase activity, but not nuclear localization of SAMHD1, is important for its sup
171 beta) pathway, exposure to ligand stimulates nuclear localization of Smad proteins, which then regula
172 hermore, loss of PRL-3 efficiently abolished nuclear localization of STAT3 and reduced its occupancy
176 signaling involving VE-cadherin, triggering nuclear localization of the Hippo pathway transcriptiona
179 tem cell (ESC) differentiation by inhibiting nuclear localization of the MYC transcription factor NME
180 eactive oxygen species production, increased nuclear localization of the NRF2 transcription factor, i
183 d group of LMNB1 result in a decrease in the nuclear localization of the protein and an increase in m
185 in the N-terminal part of Rep is pivotal for nuclear localization of the Rep protein from Tomato yell
187 t chain kinase in the cytoplasm and enhanced nuclear localization of the transcription factor NFAT.
188 n peptide flg22 Moreover, AtOXR2 affects the nuclear localization of the transcriptional coactivator
190 ility are paralleled by modifications in the nuclear localization of the transcriptional regulator YA
191 ermeability, significant cellular uptake and nuclear localization of these Cu complexes was observed.
194 cient B cell progenitors exhibited increased nuclear localization of transcription factor binding to
195 tically, we found that DMF treatment reduced nuclear localization of transcriptional coactivator with
196 ent with NAM is sufficient to facilitate the nuclear localization of TyrRS that activates PARP1.
197 e forming a heterodimer with AR-FL to induce nuclear localization of unliganded AR-FL, AR-V7 does not
198 of virus entry in a manner dependent on the nuclear localization of Vpr and its interaction with the
199 Bcl-6, c-Myc), reduced proliferation (Ki67), nuclear localization of XPO1 cargos (p53, PTEN), and inc
200 In particular, ARF knockdown reduced non-nuclear localization of YAP which led to an increase in
202 ation of Cx43 hemichannels was necessary for nuclear localization of Yap/Taz and induction of prolife
203 kPa) led to a decrease in the cell area and nuclear localization of YAP/TAZ, and subsequent stiffeni
205 sarcoma cell lines, immunoblotting confirmed nuclear localization of YAP1 and TAZ, corresponding to t
208 interactions caused either AHR constitutive nuclear localization or failure to translocate to nucleu
212 RTKs can translocate to the nucleus via a nuclear localization sequence (NLS) present on the recep
214 e LSD1 complex through its domain containing nuclear localization sequence and phosphorylation sites.
216 fused to a yellow fluorescent protein and a nuclear localization sequence to simplify quantitative n
217 trol, PELP1-wt, or mutant PELP1 in which the nuclear localization sequence was altered, resulting in
219 e central region of ING5, which contains the nuclear localization sequence, is flexible and disordere
222 neered variants of Cas12a with two different nuclear localization sequences (NLS) on the C terminus p
224 asmic-nuclear transitions, several classical nuclear localization sequences in the N terminus of the
225 y of importin-alpha (Imp-alpha) to recognize nuclear localization sequences, without effecting the Im
228 uctural analysis suggests that a monopartite nuclear localization signal (NLS) may reside in the N-te
229 s simplex virus 1 (HSV-1) mutant lacking the nuclear localization signal (NLS) on the ICP0 gene (0Del
231 d that the ring component anillin contains a nuclear localization signal (NLS) that binds to importin
232 ted mutant mouse, nBmp2NLS(tm), in which the nuclear localization signal (NLS) was inactivated to pre
233 at CRWN4 is coimported into the nucleus with nuclear localization signal (NLS)-bearing paralogues in
235 plasma membrane and modulates its binding to nuclear localization signal (NLS)-containing proteins th
236 triphosphate (RanGTP) gradient that imports nuclear localization signal (NLS)-specific cargoes (NLS-
239 rtin beta1- and 2-dependent proline-tyrosine nuclear localization signal (PY-NLS), which has a unique
240 owed us to identify a structurally conserved nuclear localization signal and amino acids involved in
241 ivities of both a peptide-encoded N-terminal nuclear localization signal and C-terminal nuclear expor
243 thin the catalytic domain of PfCCT acts as a nuclear localization signal and its deletion decreases t
245 try to show that ICAP1 contains a functional nuclear localization signal and that nuclear localizatio
248 ed function of PHLPP1 depends on a bipartite nuclear localization signal in its unique N-terminal ext
250 capsid protein, which is positioned within a nuclear localization signal in the cyclophilin A-binding
251 trafficking elements, including a canonical nuclear localization signal in the extreme C terminus an
253 e these sequences do not correspond to known nuclear localization signal motifs, they represent a new
255 eered a Fyn biosensor with a light-inducible nuclear localization signal to demonstrate that the Fyn
256 rions parallels effects of the attachment of nuclear localization signal to Sis1, indicating that Cur
261 region 2 of ZO-2, and S261 located within a nuclear localization signal, are critical for the intera
262 ncharacterized region of Dnmt3a1 including a nuclear localization signal, has very low activity in TK
263 We fuse the ADAR2 domain, tagged with a nuclear localization signal, to an RNA binding peptide f
273 However, M protein mutants with weakened nuclear localization signals (NLS) and deficient nuclear
274 d the nuclear translocation of CEBPD through nuclear localization signals (NLS) to activate PRKDC-med
275 ycete plant pathogen Phytophthora sojae uses nuclear localization signals (NLSs) for translocation of
277 The specific interaction of importins with nuclear localization signals (NLSs) of cargo proteins no
278 ngaged via the EHM-targeting signals and the nuclear localization signals (NLSs), as well as the nucl
279 tinct host import factors that interact with nuclear localization signals in the Gag MA and NC domain
280 These features include enhancement of the nuclear localization signals in the nucleocapsid protein
281 intrinsically disordered domains containing nuclear localization signals into the central channel fo
283 , in which TAL effectors harbor their T3 and nuclear localization signals, and activation domain.
284 E344Q substitution reduces KPNA7 binding to nuclear localization signals, and that this limits KPNA7
287 an acetylation-dependent regulation of PD-L1 nuclear localization that governs immune-response gene e
288 domain also plays a critical role in hLysRS nuclear localization, thus facilitating noncanonical fun
289 ing hypothesis that influenza virus exploits nuclear localization to delay activation of the innate i
291 tus loss-of-function alleles decrease Dorsal nuclear localization ventrally, where Toll signals are h
292 s conditions and expression of CTT1 Msn2-GFP nuclear localization was increased in the siw14Delta.
293 d dipeptides were present in the nucleus and nuclear localization was necessary and sufficient for th
295 itionally, the K252 SUMOylation site and NS5 nuclear localization were required for ZIKV NS5 to regul
296 om coalescing into PBs without affecting its nuclear localization, whereas overexpression of PCH1 dra
297 The inhibitory effect of AnkG requires its nuclear localization, which depends on p32-dependent int
298 ect the slope of the correlation between YAP nuclear localization with area, but did decrease overall
300 tly as competitive antagonists, blocking AhR nuclear localization, XRE binding, and target gene induc