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1 MRKTKLAPT (residues 16 to 24) that acts as a nuclear localization signal.
2 ted to nuclei after exposure of a C-terminal nuclear localization signal.
3 s induction, although AnkG lacks a predicted nuclear localization signal.
4 mutation is combined with the deletion of a nuclear localization signal.
5 by driving Esp1 into the nucleus with a SV40 nuclear localization signal.
6 tional changes in the STAT3 dimer masked its nuclear localization signal.
7 ed' fluorescent proteins sandwiched around a nuclear localization signal.
8 red a Fyn kinase domain with light-inducible nuclear localization signal.
9 ains a nuclear export signal (NES) but not a nuclear localization signal.
10 uttling of Staufen1 into the nucleus via its nuclear localization signal.
11 -based domains, a proline-rich region, and a nuclear localization signal.
12 Its N-terminus harbors a nuclear localization signal.
13 inase-2 inhibitor or by mutating a predicted nuclear localization signal.
14 ncluding a functional coiled-coil domain and nuclear localization signal.
15 rt, and serine 114, within a PKA site in the nuclear localization signal.
16 h-like nuclear export signal and an adjacent nuclear localization signal.
17 n-fluorescent-protein (CFP), with or without nuclear localization signal.
18 tandem zinc finger domain contains an active nuclear localization signal.
19 n, and (3) in sequence pattern searching for nuclear localization signal.
20 of the importin beta family, via a conserved nuclear localization signal.
21 were full length, containing the N-terminal nuclear localization signal.
22 way for mediating ligand-induced exposure of nuclear localization signal.
23 both the C-terminal basic stretch and basic nuclear localization signal.
24 calize TRAF3 to the nucleus via a functional nuclear localization signal.
25 es its C-terminal transmembrane domain and a nuclear localization signal.
26 band at 95-100 kDa, which lacked N-terminal nuclear localization signals.
27 were achieved by selectively mutating virion nuclear localization signals.
28 y chosen nucleoplasmic sequences and 12% for nuclear localization signals.
29 ith Srp1, a nuclear import factor that binds nuclear localization signals.
30 trast, has little effect on KPNA7 binding to nuclear localization signals.
31 e the nuclear import of viral genome via its nuclear localization signals.
32 identified, including a bipartite classical nuclear localization signal, a mitochondrial matrix targ
33 c that control its localization, including a nuclear localization signal, a nuclear retention domain
35 s introduced to ablate a previously reported nuclear localization signal also resulted in a significa
36 referred to as pUL31, containing a bipartite nuclear localization signal, an intrinsically disordered
37 has four targeting sequences: two classical nuclear localization signals, an INM sorting motif, and
38 ontains 2 separable functional signatures, a nuclear localization signal and a putative EDGE motif, t
39 owed us to identify a structurally conserved nuclear localization signal and amino acids involved in
41 lude that exons 5-15 of kazrin, encoding the nuclear localization signal and C-terminal domain, are n
42 ivities of both a peptide-encoded N-terminal nuclear localization signal and C-terminal nuclear expor
43 vely spliced Set-beta transcript lacking the nuclear localization signal and demonstrated that the fu
45 The truncated Leo1(LA1186) protein lacks a nuclear localization signal and is distributed mostly in
48 thin the catalytic domain of PfCCT acts as a nuclear localization signal and its deletion decreases t
50 One of its isoforms, DNAJB6a, contains a nuclear localization signal and regulates beta-catenin s
51 is behavior requires coordinated action of a nuclear localization signal and reversible G protein (he
52 try to show that ICAP1 contains a functional nuclear localization signal and that nuclear localizatio
53 Both proteins contain a consensus bipartite nuclear localization signal and were found in the nucleu
54 e splicing, but specific Rbfox isoforms lack nuclear localization signals and accumulate in the cytop
55 gle-pass transmembrane protein with multiple nuclear localization signals and no known domains or mot
56 ype of targeting motif that is distinct from nuclear localization signals and that can be computation
57 retains conserved Myc box regions but lacks nuclear localization signals and the bHLHZ domain essent
58 e N-terminally truncated PTBP3 isoforms lack nuclear localization signals and/or most of the RRM1 dom
60 protein sequence indicated the presence of a nuclear localization signal, and subcellular fractionati
62 , in which TAL effectors harbor their T3 and nuclear localization signals, and activation domain.
63 show that NF-kappaB dimerization properties, nuclear localization signals, and binding to cytosolic I
65 E344Q substitution reduces KPNA7 binding to nuclear localization signals, and that this limits KPNA7
66 region 2 of ZO-2, and S261 located within a nuclear localization signal, are critical for the intera
69 the sumoylation site at Lys(1172) or of the nuclear localization signal at Lys(1147) abolished L1-st
70 ion of R495X FUS, which abrogates a putative nuclear localization signal at the C-terminus of FUS, in
71 s to the N-terminal DNA-binding domains, the nuclear localization signal becomes more highly exchangi
73 , tumor-derived mutant LT (MCV350) lacking a nuclear localization signal binds hVam6p but fails to in
74 h a kinase substrate is fused to a bipartite nuclear localization signal (bNLS) and nuclear export si
76 utive import of proteins harboring a classic nuclear localization signal (cNLS) or the spontaneous nu
78 cell death with defects in M9- and classical nuclear localization signal (cNLS)-mediated protein impo
79 elated isoforms contains predicted classical nuclear localization signals (cNLS) within exons 7 and 1
82 A longer DCL4 transcript isoform encoding a nuclear localization signal, DCL4(NLS), is present in Ar
83 A, K364A, and K376A) in conjunction with the nuclear localization signal deletion did not result in c
84 rther, overexpression of TEF3-1, but not its nuclear localization signal-deletion mutant (TEF3-DeltaN
85 mouse overexpressing exogenous FUS without a nuclear localization signal (DeltaNLS-FUS), which develo
87 he RanBP9-Delta1/N60 fragment, which lacks a nuclear localization signal, displayed enhanced cytoplas
89 olipase A2 function for endosomal escape and nuclear localization signals for nuclear targeting and (
90 saturated, nonactivating fatty acids inhibit nuclear localization signal formation by destabilizing t
91 tein, and this localization is dictated by a nuclear localization signal found in the Adi3 T-loop ext
94 dopsis TET genes was investigated by pAtTET::NUCLEAR LOCALIZATION SIGNAL-GREEN FLUORESCENT PROTEIN/be
95 ncharacterized region of Dnmt3a1 including a nuclear localization signal, has very low activity in TK
96 minal 25 amino acids of MxB to function as a nuclear localization signal; however, the ability of the
97 t at residues 11-27 and an isoleucine-lysine nuclear localization signal (IK-NLS) motif at residues 3
98 This difference, together with the lack of a nuclear localization signal in any of the AnkA orthologu
101 mutations have been shown to deteriorate the nuclear localization signal in FUS and thereby facilitat
103 ed function of PHLPP1 depends on a bipartite nuclear localization signal in its unique N-terminal ext
106 l in the hinge domain, we identified a novel nuclear localization signal in the A/B domain of thyroid
107 a mechanism whereby L takes advantage of the nuclear localization signal in the COOH region of 2A to
108 capsid protein, which is positioned within a nuclear localization signal in the cyclophilin A-binding
109 trafficking elements, including a canonical nuclear localization signal in the extreme C terminus an
110 ice expressing human TDP-43 with a defective nuclear localization signal in the forebrain (hTDP-43-De
112 on of WT GRs or those with a mutation in the nuclear localization signal in the muscle of MGRKO mice
114 asmic shuttling protein, and it contains two nuclear localization signals in the basic region and one
115 ucleocapsids, which leads to the exposure of nuclear localization signals in the C terminus of core p
117 tinct host import factors that interact with nuclear localization signals in the Gag MA and NC domain
118 These features include enhancement of the nuclear localization signals in the nucleocapsid protein
119 inantly in the nucleus through the action of nuclear localization signals in the repeated regions of
120 ocalization studies identified and confirmed nuclear localization signals in XLG2 and XLG3 and a nucl
122 intrinsically disordered domains containing nuclear localization signals into the central channel fo
124 nus of green fluorescent protein (GFP) and a nuclear localization signal is fused to the amino termin
125 distribution of NRDE-3 requires a functional nuclear localization signal, is required for nuclear RNA
126 shorter isoform, which lacks the N-terminal nuclear localization signal, is restricted to the cytopl
128 rt of TDP-43 protein, as a disruption of its nuclear localization signal leads to mislocalization and
129 Instead, this ability is dependent on a nuclear localization signal located in its N-terminal 40
132 e these sequences do not correspond to known nuclear localization signal motifs, they represent a new
133 interacted with recombinant NEMO but not the nuclear localization signal mutant version and induced n
136 nlike most substrates that carry a classical nuclear localization signal (NLS) and bind to importin a
137 N-terminal region of FMDV 3D that acts as a nuclear localization signal (NLS) and in template bindin
138 mpelling evidence that Cby harbors bona fide nuclear localization signal (NLS) and nuclear export sig
139 A fusion protein between RecA containing a nuclear localization signal (NLS) and the DNA-binding do
142 plex, eVP24 recognizes a unique nonclassical nuclear localization signal (NLS) binding site on KPNA5
144 in-of-function genetic approach, a bipartite nuclear localization signal (NLS) derived from the nucle
145 ctional studies that UNE-S harbours a robust nuclear localization signal (NLS) directing SerRS to the
146 AR protein domains, including the canonical nuclear localization signal (NLS) in the AR hinge region
147 e describe the identification of a potential nuclear localization signal (NLS) in the C-terminal regi
148 pha) can translocate proteins that contain a nuclear localization signal (NLS) into the nucleus.
152 The study documents multifunctionality of a nuclear localization signal (NLS) located at the N-termi
153 leasing importin alpha/beta from a bipartite nuclear localization signal (NLS) located in the tail do
154 uctural analysis suggests that a monopartite nuclear localization signal (NLS) may reside in the N-te
156 nteraction domain although it does possess a nuclear localization signal (NLS) motif, whilst Cry3 lac
157 ts with hBVR nuclear export signal (NES) and nuclear localization signal (NLS) mutants demonstrated i
159 e recharacterized the importin-alpha binding nuclear localization signal (NLS) of rat ChREBP, identif
161 at Ser826 and Ser828, located in a putative nuclear localization signal (NLS) on the Drosophila mela
162 s simplex virus 1 (HSV-1) mutant lacking the nuclear localization signal (NLS) on the ICP0 gene (0Del
167 ition of the simian virus 40 large-T-antigen nuclear localization signal (NLS) results in the nuclear
171 e analyzed the structure and conservation of nuclear localization signal (NLS) sequences previously i
172 d that the ring component anillin contains a nuclear localization signal (NLS) that binds to importin
173 egument protein VP1-2 contains an N-terminal nuclear localization signal (NLS) that is critical for c
175 inase acting on RNA (ADAR1) carries a unique nuclear localization signal (NLS) that overlaps one of i
177 scent protein (GFP) reporter fusion assays a nuclear localization signal (NLS) that was mapped to a 2
178 1 (M1) of influenza virus A/WSN/33 when its nuclear localization signal (NLS) was disrupted by R101S
179 ted mutant mouse, nBmp2NLS(tm), in which the nuclear localization signal (NLS) was inactivated to pre
180 for nuclear localization, and a nonclassical nuclear localization signal (NLS) was mapped to a short,
182 y, we report that Nurr1 contains a bipartite nuclear localization signal (NLS) within its DNA binding
184 he CTD of topo IIalpha, while preserving the nuclear localization signal (NLS), enhances the decatena
185 ntaining a cell penetrating peptide (CPP), a nuclear localization signal (NLS), or a bifunctional CPP
186 ents and translocated into the nucleus via a nuclear localization signal (NLS), specific among kerati
187 serine and threonine residues adjacent to a nuclear localization signal (NLS), thereby abrogating it
188 at CRWN4 is coimported into the nucleus with nuclear localization signal (NLS)-bearing paralogues in
190 RanGTP is required in the nucleus to release nuclear localization signal (NLS)-containing cargo from
192 plasma membrane and modulates its binding to nuclear localization signal (NLS)-containing proteins th
193 alpha's mediate nuclear transport by linking nuclear localization signal (NLS)-containing proteins to
194 plasmodesmata, targeted to the nucleus in a nuclear localization signal (NLS)-dependent manner, wher
195 pherin heterodimer alpha2beta1 in vitro in a nuclear localization signal (NLS)-dependent manner.
196 triphosphate (RanGTP) gradient that imports nuclear localization signal (NLS)-specific cargoes (NLS-
206 However, M protein mutants with weakened nuclear localization signals (NLS) and deficient nuclear
209 nit, Importin alpha (Imp alpha), and variant nuclear localization signals (NLS) representing a range
210 d the nuclear translocation of CEBPD through nuclear localization signals (NLS) to activate PRKDC-med
211 with (30-nm diameter) and without (< 10 nm) nuclear localization signals (NLS), macroscopic transpor
215 importin Kap95, which functions on classical nuclear-localization signal (NLS)-bearing substrates.
216 amino-terminal residues (1-45) including the nuclear localization signal (NLS1) are dispensable.
218 sine residues within the peptides containing nuclear localization signals (NLSs) 1 and 2 were non-ace
219 ycete plant pathogen Phytophthora sojae uses nuclear localization signals (NLSs) for translocation of
220 classical nucleocytoplasmic import pathway, nuclear localization signals (NLSs) in cargo proteins ar
223 use model with mutations that inactivate the nuclear localization signals (NLSs) of Apc (Apc(mNLS)).
224 The specific interaction of importins with nuclear localization signals (NLSs) of cargo proteins no
225 destined for import into the nucleus contain nuclear localization signals (NLSs) that are recognized
226 , unlike their bacterial homologues, possess nuclear localization signals (NLSs) to enter the cell nu
227 karyotic proteins have been shown to contain nuclear localization signals (NLSs), although its biolog
228 ngaged via the EHM-targeting signals and the nuclear localization signals (NLSs), as well as the nucl
231 l strains of influenza A viruses contain two nuclear localization signals (NLSs): a well-studied mono
232 h NRF-2alpha and NRF-2beta contain intrinsic nuclear localization signals (NLSs): the Ets domain with
234 specific modular signals for nuclear import (nuclear localization signals, NLSs) and export (nuclear
235 ) phosphorylation at S659, which exposed the nuclear localization signal of ACSS2 for importin alpha5
236 Five phosphorylation sites reside around the nuclear localization signal of Alp7, and the phosphodefi
237 mouse with point mutations in the canonical nuclear localization signal of CMAS, which relocated the
239 e novo predicted deleterious variants in the nuclear localization signal of Heterogeneous Nuclear Rib
240 of MxB to bind to HIV-1 capsid and (ii) the nuclear localization signal of MxB, which is important f
242 grow in glycerol medium, and removal of the nuclear localization signal of Rat1, the nuclear homolog
243 leus in SBMA, we genetically manipulated the nuclear localization signal of the polyglutamine-expande
244 hydrophobic domain and a proximal C-terminal nuclear localization signal of VP4 were required for (i)
247 initiation sites: one (short form) with the nuclear localization signal only, exclusively localized
248 tein (FKBP12) fused to a cellular 'address' (nuclear localization signal or nuclear export sequence).
249 r demonstrated via the assembly of stable QD-nuclear localization signal peptide bioconjugates that p
250 tin-beta in its free form or in complex with nuclear localization signal peptides as the starting con
252 BPN1 but not a truncated version lacking the nuclear localization signal protects from pathogenic TDP
254 or transportin recognizes a proline-tyrosine nuclear localization signal (PY-NLS) in the N-terminal t
256 rtin beta1- and 2-dependent proline-tyrosine nuclear localization signal (PY-NLS), which has a unique
259 the cargo proteins, including the classical nuclear localization signals, recognized by the adaptor
260 ed by the adaptor importin-alpha, and the PY nuclear localization signals, recognized by transportin-
261 s a well-characterized basic amino acid-rich nuclear localization signal region at positions 101 to 1
262 data demonstrate that the positively charged nuclear localization signal region in the tail in apo-Os
266 ed cereals showed that all of them contain a nuclear localization signal sequence flanking to the K1
269 targeted to nuclei, through the fusion with nuclear localization signal, still exerts strong antipro
270 chloroplast targeting signal and a putative nuclear localization signal, suggesting that they are du
272 tion factor SP1, and coexpression of SP1 and nuclear localization signal-tagged HSP27 synergistically
274 and that Orc6 and Orc1 each contain a single nuclear localization signal that is essential for nuclea
276 found that residues (20)KY(21) constitute a nuclear localization signal that is not required for the
277 gly, 817-1314 possesses a conserved putative nuclear localization signal that may facilitate the nucl
278 f these elements consists of a high-affinity nuclear localization signal that mediates indirect tethe
279 nteracts with importin alpha via a classical nuclear localization signal that recruits importin alpha
280 rization and restricting access to a primary nuclear localization signal through which the apoptogeni
281 uitment by mutating Ser rich clusters of the nuclear localization signal to Ala abolished nuclear imp
282 eered a Fyn biosensor with a light-inducible nuclear localization signal to demonstrate that the Fyn
283 rions parallels effects of the attachment of nuclear localization signal to Sis1, indicating that Cur
285 ic construction is also used in multipartite nuclear localization signals to provide broad substrate
286 We fuse the ADAR2 domain, tagged with a nuclear localization signal, to an RNA binding peptide f
289 e N-terminal 25 amino acids to function as a nuclear localization signal was not required for restric
290 pocotyl 1 (FHY1) and fhy1-like, an intrinsic nuclear localization signal was proposed to be involved
291 o called PAD4 or PADV), the only PADI with a nuclear localization signal, was previously shown to act
292 e PredictNLS algorithm uncovered a potential nuclear localization signal, whereas the algorithm DBS-P
293 t present in the shorter isoform, contains a nuclear localization signal, whereas the C terminus of B
296 ntry of dreCmas1 was mediated by a bipartite nuclear localization signal, which seemed irrelevant for
297 nvolves both a nuclear export sequence and a nuclear localization signal, whose activities are regula
299 the ligand-sensing beta2 loop and a tertiary nuclear localization signal within the alpha-helical cap
300 reintegration complex is further promoted by nuclear localization signals within the nucleocapsid and