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1 the absence of TDP-43 aggregation or loss of nuclear protein.
2 -3 or AIB1), a large and mostly unstructured nuclear protein.
3 reonine residues of membrane, cytosolic, and nuclear proteins.
4 ration of [4Fe-4S] clusters in cytosolic and nuclear proteins.
5 f serine/threonine residues of cytosolic and nuclear proteins.
6 ntrolling the subnuclear localization of the nuclear proteins.
7 ill no reliable and quantitative resource of nuclear proteins.
8 ell immunoblots to detect both cytosolic and nuclear proteins.
9 the export of nuclear RNA and the import of nuclear proteins.
10 correlates with increased ubiquitination of nuclear proteins.
11 g the linker histone in the context of other nuclear proteins.
12 n RNR and the Fe-S clusters in cytosolic and nuclear proteins.
13 atrophy restricted the transport of smaller nuclear proteins.
14 sm distinct from the Srp1-mediated import of nuclear proteins.
15 e and/or threonine residues of cytosolic and nuclear proteins.
16 ohydrate modification found on cytosolic and nuclear proteins.
17 to investigate cofractionation of groups of nuclear proteins.
18 important role for export in the turnover of nuclear proteins.
19 r (EGFR) that phosphorylates cytoplasmic and nuclear proteins.
20 neutrophil extracellular traps that contain nuclear proteins.
21 disorganization of lamin A/C and leakage of nuclear proteins.
22 otein lamin A distorts nuclei and sequesters nuclear proteins.
23 HBoV1 encodes a small nonstructural protein, nuclear protein 1 (NP1), that plays an essential role in
25 poptotic markers and increased expression of nuclear protein 1 and tribbles related protein-3 compare
28 ase of the high-mobility group box 1 (Hmgb1) nuclear protein, activating the sterile inflammatory res
29 n increased levels of constitutively cleaved nuclear protein and increased transcription and secretio
33 (HMGB1) is an abundant chromatin-associated nuclear protein and released into the extracellular mili
34 reactivity to the conserved influenza virus nuclear protein and to heterovariant and heterosubtypic
36 n of OGT affects O-GlcNAcylation of numerous nuclear proteins and acetylation of Lys-9 on histone 3 i
38 nonstructural proteins, the presence of cell nuclear proteins and the viral nucleocapsid protein incr
39 histones, which are the major components of nuclear proteins and their consequences in COPD, has not
40 SUMO system appears to predominantly target nuclear proteins and, to a lesser extent, cytosolic prot
43 -redundant: USP28 stabilizes c-MYC and other nuclear proteins, and USP25 regulates inflammatory TRAF
44 d B cells; NO generation; S-nitrosylation of nuclear proteins; and DNA accessibility as reflected by
45 s lack of understanding of the site(s) where nuclear proteins are degraded because the subcellular di
46 to the nucleus, it is also evident that some nuclear proteins are degraded only after export to cytos
50 ochemistry using neuronal (neuronal-specific nuclear protein), astrocytic (glial fibrillary acidic pr
52 with the C-terminal SANT/Myb-like domain of nuclear protein, ataxia-telangiectasia locus (NPAT), a t
55 s (rat 832/13 and mouse MIN6), and increased nuclear protein binding compared with the rs11708067-G a
56 ficant SNP, rs4730222, exhibits differential nuclear protein binding in electrophoretic mobility shif
57 obility shift assays indicated that specific nuclear protein bindings occur at the three SNPs in HepG
60 ormation are found not only in cytosolic and nuclear proteins, but also in membrane-associated protei
61 cause nuclear rupture and mislocalization of nuclear proteins, but damage to DNA remains uncertain, a
62 syltransferase that modifies cytoplasmic and nuclear protein by transfer of N-acetylglucosamine (O-Gl
64 gulates mitochondrial respiration, but how a nuclear protein can orchestrate the function of an organ
66 merase-1 (PARP-1), a ubiquitous and abundant nuclear protein, catalyzes the synthesis of a negatively
67 endocytosed ligands, and on a motley crew of nuclear proteins, chromatin modifiers, ubiquitin ligases
70 ,389 mutants in the library, covering 83% of nuclear protein-coding genes, are available to the commu
71 inth interrelationships based on hundreds of nuclear protein-coding genes, exploring phylogenetic sig
72 odelling, replacing the separate cytoplasmic/nuclear protein compartments that were characteristic of
78 inct substructures and distinguishes between nuclear proteins confined to the nucleus and those that
83 tal Cell, Cooper et al. (2014) report that a nuclear protein, cyclin C, is recruited from nuclei to m
86 trophoretic mobility shift assays with MCF-7 nuclear protein demonstrate differential binding of the
89 K51 by Sirt1 allows LC3 to interact with the nuclear protein DOR and return to the cytoplasm with DOR
91 e provide definitive evidence that the viral nuclear protein EBNA3C is essential in EBV-infected prim
92 ivity is critically dependent on C11orf46, a nuclear protein encoded in the chromosome 11p13 WAGR ris
95 ticularly dependent on the EBV SM protein, a nuclear protein expressed early during lytic reactivatio
100 responses, we performed mass spectrometry on nuclear proteins extracted from Cre-negative controls an
102 based on its presence in sugarcane internode nuclear protein extracts, and protoplast transactivation
103 DNA was much lower in mitochondrial than in nuclear protein extracts, and resulted in persistent DNA
105 e formation of microscopically visible RAD51 nuclear protein foci occurring in the absence of any DNA
109 EMSAs) were performed to investigate whether nuclear proteins from these cell lines bind SNP alleles
114 erizing a Phaeodactylum tricornutum bHLH-PAS nuclear protein, hereby named RITMO1, we shed light on t
119 sically and functionally interacts with some nuclear proteins, i.e. the lymphoid enhancer-binding fac
121 ent of IMPbeta1- or IMPalpha/beta1-dependent nuclear protein import specifically, whereas specific al
125 Here we document that BTBD18 is a pachytene nuclear protein in mouse testes that occupies a subset o
126 roscopy that Ago2 is distributed mainly as a nuclear protein in primary human foreskin keratinocytes
127 es reveals that Ago2 exhibits primarily as a nuclear protein in skin, normal cervix, and cervical can
128 valuation in a phase I/II clinical trial for nuclear protein in testis (NUT) midline carcinoma and ot
129 ain helicase DNA-binding protein 5) and NUT (nuclear protein in testis) were also demonstrated to be
132 proteasome-dependent degradation of specific nuclear proteins in mammalian cells and zebrafish embryo
133 e demonstration of O-GalNAc glycosylation of nuclear proteins in mammalian cells reported here has im
134 that NAD(+)-dependent SIRT1, RELB, and SIRT6 nuclear proteins in monocytes regulate a switch from the
136 that the transport properties of these model nuclear proteins in myotubes depended on molecular weigh
138 oteins, including membrane, cytoplasmic, and nuclear proteins in T cells and embryonic stem cells.
140 control molecules, generally presumed to be nuclear proteins in the human beta-cell, are in fact con
141 -linked glycosylation (O-GalNAc) as a PTM of nuclear proteins in the human cell has not been previous
142 an biosynthesis, representing a novel PTM of nuclear proteins in the nucleus of human cells, with an
144 xploring San1, which ubiquitinates misfolded nuclear proteins in yeast for proteasomal degradation.
146 sly shown to interact with a growing list of nuclear proteins including chromatin remodeling complexe
147 ty is mediated in part by S-nitrosylation of nuclear proteins, including MTA3 (Metastasis Associated
148 eles showed differential binding to multiple nuclear proteins, including stronger IRF2 binding to the
149 intained by the concerted action of numerous nuclear proteins, including that of the linker histone H
150 ccinylation is also present on cytosolic and nuclear proteins; indeed, we show that a substantial fra
151 5fC uniquely interacts and reacts with key nuclear proteins, indicating functions in genome regulat
153 -dependent differences for rs13082711 in DNA-nuclear protein interactions, where the risk allele is a
154 AF-A), originally identified as a structural nuclear protein, interacts with chromatin-associated RNA
156 nji domain-containing protein 6 (JMJD6) is a nuclear protein involved in histone modification, transc
157 ed here demonstrate that CPS1 is a bona fide nuclear protein involved in homocitrullination (hcit), i
158 , and Runt-related transcription factor 2, a nuclear protein involved in osteoblastic differentiation
159 talloproteinases-2 and -9), and nucleolin (a nuclear protein involved with synthesis and maturation o
160 eome analysis highlighted acetylation on key nuclear proteins involved in the DNA damage response and
162 ne (GlcNAc) to Ser or Thr in cytoplasmic and nuclear proteins is a well known post-translational modi
165 hown that p63, a member of the p53 family of nuclear proteins, is expressed in proliferative cytotrop
166 One hour postinhalation, sputum was induced, nuclear proteins isolated from purified macrophages, and
167 result of SIRT6-mediated deacetylation, PKM2 nuclear protein kinase and transcriptional coactivator f
170 ell-conserved family of essential eukaryotic nuclear proteins known to be stress activated and involv
171 formability by twofold overexpression of the nuclear protein lamin A or we introduce into the cells s
175 the formation of NETs through proteolysis of nuclear proteins leading to chromatin decondensation.
177 dementia (IBM-PFD)-together with its adaptor nuclear protein localization (NPL)4, specifically intera
180 ist that upregulates CD1d expression via the nuclear protein, lymphoid enhancer-binding factor 1 (LEF
181 pathway regulated by retinoic acid-regulated nuclear protein made the largest contribution to this ge
183 ple motile cilia (RGMC), have implicated the nuclear protein MCIDAS (MCI), in the transcriptional reg
185 Previously we identified the multifunctional nuclear protein NONO as a partner of circadian PERIOD (P
189 teins identified HAI1-Interactor 1 (HIN1), a nuclear protein of unknown function which could be depho
192 ve cellular injury results in the release of nuclear proteins, of which histones are the most abundan
196 Damaged DNA-binding protein 2 (DDB2), a nuclear protein, participates in both nucleotide excisio
197 Here, we report that the recently described nuclear protein, Pax2 transactivation domain interaction
199 DUF2128 family is related to the eukaryotic nuclear protein positive cofactor 4 (PC4) family and to
200 ormaldehyde (FA) that binds to cytosolic and nuclear proteins producing proteotoxic stress and genoto
202 r, unlike NMNAT1, NAMPT is not known to be a nuclear protein, prompting the question of how the nucle
203 mmarize the known and implicated pathways of nuclear protein quality control, and identify the unreso
204 m chloroplasts and mitochondria merge at the nuclear protein RADICAL-INDUCED CELL DEATH1 (RCD1).
205 9 (HEAT9) loop, which regulates GTP-binding nuclear protein Ran binding and cargo release, contains
206 fects on the nucleus by trapping Ras-related nuclear protein (RAN) and preventing it from transportin
209 to those found in the eukaryotic Ras-related nuclear protein (Ran) guanine nucleotide exchange factor
210 further show that the flagellar Ras-related nuclear protein (Ran) guanosine 5'-triphosphate (GTP) gr
211 ctroscopy technique to study the ras-related nuclear protein (Ran) pathway, which forms soluble gradi
212 tional insight into the details of misfolded nuclear protein recognition and demonstrate that there i
213 rate that endogenous cGAS is predominantly a nuclear protein, regardless of cell cycle phase or cGAS
214 e (O-GlcNAc) modification of cytoplasmic and nuclear proteins regulates fundamental cellular processe
215 Immunofluorescence microscopy studies of nuclear proteins revealed costaining between PABP1 and m
216 o nuclei, thus favoring local NO production, nuclear protein S-nitrosylation, and induction of mitoch
219 In order to determine whether activated nuclear protein STAT3 binds to the MMP3 promoter and reg
221 RAN) and preventing it from transporting key nuclear proteins such as, DNMT3A, for maintaining normal
222 AHLs also share interactions with other nuclear proteins, such as transcription factors, suggest
224 liver revealed a striking depletion of most nuclear proteins, suggesting that nuclear protein export
226 Ramazzottius varieornatus contains a unique nuclear protein termed Dsup, for damage suppressor, whic
230 me to our knowledge that TRAF3 is a resident nuclear protein that associates with the transcriptional
231 Here we investigate the role of Ldb1, a nuclear protein that binds directly to all LIM-HD factor
232 es pombe histone chaperone Sim3 is a soluble nuclear protein that binds the histone variant CenH3 and
235 RBM14 that is associated with XPO1 (CRM1), a nuclear protein that binds to the HIV-1 Rev protein and
236 up protein B-1 (HMGB1) is a highly conserved nuclear protein that can be actively secreted by innate
240 Pre-mRNA processing protein 40 (Prp40) is a nuclear protein that has a role in pre-mRNA splicing.
242 5 and the active kinase domain of JAK2, is a nuclear protein that has the ability to bind to wild-typ
243 Rad23 can bind Ho-endonuclease (Ho-endo), a nuclear protein that initiates mating-type switching in
246 Defective entry into mitosis 1 (Dim1) is a nuclear protein that is implicated in pre-mRNA splicing
247 angiectasia mutated (ATM) is predominantly a nuclear protein that is involved in the early recognitio
249 ependent mutations in PRDM6, which encodes a nuclear protein that is specific to vascular smooth musc
253 hatase 1 (NIPP1) is a ubiquitously expressed nuclear protein that regulates functions of protein seri
256 asis suppressor 1 (BRMS1) is a predominantly nuclear protein that suppresses metastasis in multiple h
258 s in methyl-CpG-binding protein 2 (MeCP2), a nuclear protein that, in neurons, regulates transcriptio
260 allowing for the cytoplasmic accumulation of nuclear proteins that are then available to function in
261 nate chromosomal regions via modification of nuclear proteins that in turn may regulate genes in the
262 alian mRNA m(6)A methylosome is a complex of nuclear proteins that includes METTL3 (methyltransferase
263 chromatography-mass spectrometry to identify nuclear proteins that interact with the -794 CATT5-8 sit
267 n of lncRNAs could serve as "grip holds" for nuclear proteins to pull the genome into new positions.
268 xcessive DNA methylation, reduced binding of nuclear proteins to the methylated region and altered ex
269 es the trafficking of histone protein H2B, a nuclear protein, to the mitochondria in cancer cells.
270 each other and themselves, as well as other nuclear proteins, to form complexes which modulate plant
272 highlight a disruption of multiple essential nuclear protein trafficking pathways by polyQ-ataxin-1,
273 the transcription factor ATF4 and identified nuclear protein transcriptional regulator 1 (Nupr1), a s
274 control transcriptional regulation and intra-nuclear protein translocation of FoxM1 in polyploid cell
275 We have developed a mathematical model of nuclear protein transport within a myotube that recapitu
277 reveal an increased association of TFEB with nuclear proteins upon GSK3 and mTOR inhibition suggestin
278 normal isoaspartyl residues predominantly in nuclear proteins upon seed-specific expression in Arabid
281 ly interacted with Acinus (Acn), a primarily nuclear protein, which promotes starvation-independent,
283 eased the transport of high molecular weight nuclear proteins, while atrophy restricted the transport
284 little or no (15)N-protein contents in most nuclear proteins, while there were a broad range of (14)
288 zymes in the prenylation pathway and SAFB, a nuclear protein with both DNA and RNA binding domains.
289 that HP1BP3 is a ubiquitous histone H1 like nuclear protein with distinct and non-redundant function
292 SFPQ) is a ubiquitously expressed, essential nuclear protein with important roles in DNA damage repai
293 Methyl-CpG binding protein 2 (MeCP2) is a nuclear protein with important roles in regulating chrom
296 genetic screen in mice to identify ZFP318, a nuclear protein with two U1-type zinc fingers found in R
297 ted modifier (SUMO) to a large collection of nuclear proteins, with studies in Arabidopsis (Arabidops
300 , the principles underlying the transport of nuclear proteins within multinucleated cells remain poor