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1 activation, which may aid in regulating YAP nuclear translocation.
2 aving N-cadherin and increasing beta-catenin nuclear translocation.
3 vage of caspase-1, a step required for IL-37 nuclear translocation.
4 ing to TRIM59 binding to importin alpha5 and nuclear translocation.
5 ence, we analyzed the steps involved in DDR1 nuclear translocation.
6 ession via SAPK/JNK phosphorylation and Nrf2 nuclear translocation.
7 ress by promoting the activation of Nrf2 and nuclear translocation.
8 KPNA2), acting to reduce p65 binding and its nuclear translocation.
9 ) genes including HSP60 and GRP75, showed no nuclear translocation.
10 ivity, which stimulates SMAD3 expression and nuclear translocation.
11 s IkappaBalpha phosphorylation and NF-kappaB nuclear translocation.
12 esters NAP1L1 in the cytoplasm, blocking its nuclear translocation.
13 -activating group P65 by phosphorylation and nuclear translocation.
14 nt mTOR inhibition, thereby promoting pSTAT1 nuclear translocation.
15 log 2]) at the cell membrane, preventing its nuclear translocation.
16 ociated Nup153 is critical for its efficient nuclear translocation.
17 ad51 complex dissociation through inhibiting nuclear translocation.
18 bitor blocked STAT3 binding to myoferlin and nuclear translocation.
19 stimulated with IL-33 and resulted in NFAT1 nuclear translocation.
20 nal of ACSS2 for importin alpha5 binding and nuclear translocation.
21 plexes and was essential for TIE2/caveolin-1 nuclear translocation.
22 DG at Tyr(890) is a key stimulus for beta-DG nuclear translocation.
23 IL-6 through increased nuclear factor kappaB nuclear translocation.
24 through mTORC1-dependent repression of TFEB nuclear translocation.
25 ibility at some ER bound loci and impairs ER nuclear translocation.
26 ivated EGFR promotes FUS phosphorylation and nuclear translocation.
27 SIRT1 repression and prevents NF-kappaB p65 nuclear translocation.
28 ain, resulting in diminished DNA binding and nuclear translocation.
29 verexpressing GCB cells this caused enhanced nuclear translocation, a profoundly altered transcriptio
30 ocked NF-kappaB activation by decreasing p65 nuclear translocation, although blunting the degradation
31 activation of SAPK/JNK phosphorylation, Nrf2 nuclear translocation and antioxidant enzymes expression
32 duced increase in Keap1 and facilitated Nrf2 nuclear translocation and antioxidant gene transcription
34 y, PI3K/Akt-mediated SRF activation promotes nuclear translocation and binding of Egr2 to SOCS1 promo
35 ivity induces rapid CRTC1 dephosphorylation, nuclear translocation and binding to endogenous CREB.
36 oduction by B-1a cells in sepsis through its nuclear translocation and binding to putative responsive
37 rylation of PHB1 at Thr258, resulting in its nuclear translocation and binding to the Axin1 promoter.
39 however, C. burnetii actively prevented CHOP nuclear translocation and downstream apoptosis in a T4SS
41 In cells, malbrancheamide attenuated GRK5 nuclear translocation and effectively blocked the hypert
42 KB/Akt-mTORC1 pathway and promotes TFEB/TFE3 nuclear translocation and enhances FAM134B transcription
44 production and its ability to induce GRalpha nuclear translocation and GRE-dependent GILZ expression.
45 onsistent with these findings, impaired ITCH nuclear translocation and H1.2 polyubiquitination sensit
48 pathway mediated YAP gene expression and YAP nuclear translocation and interaction with the TEA domai
50 AMPK inhibitors prevented Ghr-induced FOXO1 nuclear translocation and negative regulation of cell pr
51 ion in response to MSU mediated by NF-kappaB nuclear translocation and NLRP3 inflammasome activation.
52 loss of the IKK complex components prevents nuclear translocation and phosphorylation of NF-kappaB,
53 These phosphorylation events promote SRPK2 nuclear translocation and phosphorylation of SR proteins
54 r analysis reveals that IKBKE regulates GLI1 nuclear translocation and promotes the reactivation of A
55 a Gli antagonist GANT58, which inhibits Gli2 nuclear translocation and PTHrP expression in tumor cell
56 interneuron development, and promoted SATB1 nuclear translocation and repositioning within the somat
57 ficantly decreased high-mobility group box 1 nuclear translocation and secretion in neurons, an effec
58 tiffness-induced CCN1 activates beta-catenin nuclear translocation and signaling and that this contri
59 he TGF-beta pathway in osteoblasts, enhanced nuclear translocation and target gene expression, and in
60 and LRP6 co-receptors, enabling beta-catenin nuclear translocation and TCF/LEF-dependent gene transac
61 RT1) repression and stimulates NF-kappaB p65 nuclear translocation and transactivation of NF-kappaB t
62 R-mediated FUS phosphorylation regulates FUS nuclear translocation and transcription of a major profi
63 ereby PGE(2) promotes Yap dephosphorylation, nuclear translocation and transcriptional activity by si
66 ng a molecular basis for hormone-independent nuclear translocation and transcriptional enhancement.
67 duced IkappaB phosphorylation, NF-kappaB p65 nuclear translocation, and activity of the NF-kappaB-spe
68 ses implicate dysregulation of ciliogenesis, nuclear translocation, and an epigenetic mechanism that
69 he TGF-beta signaling pathway, but not their nuclear translocation, and depended on oxygen availabili
71 father's lymphocytes showed reduced pSTAT4, nuclear translocation, and impaired IFN-gamma production
76 and FOXO3a phosphorylation, increased FOXO3a nuclear translocation, and upregulated high temperature
77 t the onset of differentiation and undergoes nuclear translocation as differentiation progresses.
79 The evaluation of competition relied on a nuclear translocation assay applied in a three-color ima
80 omogeneous time-resolved fluorescence assay, nuclear translocation assay, and immunofluorescence.
81 ormal IkappaBalpha degradation and NF-kappaB nuclear translocation but significantly reduced NF-kappa
82 T. gondii and IL-10 inhibited virus-induced nuclear translocation, but not phosphorylation, of IFN r
83 e applied to the nucleus directly drives YAP nuclear translocation by decreasing the mechanical restr
84 We tracked TNF-stimulated NF-kappaB RelA nuclear translocation by live-cell imaging and then quan
85 the NRON complex affects PER and CRY protein nuclear translocation, dampens amplitude, and alters per
86 amin A expression, as well as YAP and MRTF-A nuclear translocation did not show consistent trends bet
87 iptional performance of GR, but no impact on nuclear translocation, dimerization, or DNA binding capa
88 -267 by Ack1/TNK2 tyrosine kinase results in nuclear translocation, DNA binding, and androgen-depende
89 different types of stresses induce distinct nuclear translocation dynamics of the general stress-res
90 lly interacts with PD-L1 and facilitates its nuclear translocation, enhancing the transcription of th
91 uation of TGF-beta signaling, Smads and XBP1 nuclear translocation, expression of GRP78 and XBP1 (ER
92 NRF2-dependent OSGIN1 expression induced P53 nuclear translocation following MMF administration, lead
93 oplasmic beta-catenin result in insufficient nuclear translocation for full Wnt target gene transcrip
94 totoxic T lymphocyte effector functions.NFAT nuclear translocation has been shown to be required for
96 elated factor 2 (Nrf2) gene expression, Nrf2 nuclear translocation in bronchial epithelial cells, and
101 PEG3 for TFEB transcriptional induction and nuclear translocation in human umbilical vein endothelia
102 f both stimuli via the dynamics of NF-kappaB nuclear translocation in individual cells, suggesting th
104 is able to efficiently block STAT1 and STAT2 nuclear translocation in order to impair transcriptional
105 zation, hormone-dependent monomerization and nuclear translocation in PC-3 and COS-1 cells, by utiliz
106 monstrated that COX-2 was induced and showed nuclear translocation in two neuronal cell lines - mouse
107 ion, NF-kappaB binding to DNA, and NF-kappaB nuclear translocation in WT mice was exacerbated in MIOX
109 phorylates TFEB at Ser467 and represses TFEB nuclear translocation independently of mechanistic targe
111 th live cell reporters, we discover that ERK nuclear translocation is regulated in a graded manner in
112 on 6 to 9 (ARM6-9) of KAP3, required for its nuclear translocation, is also necessary and sufficient
113 it mediates PKCdelta-dependent NF-kappaB-p65 nuclear translocation, leading to inflammasome priming,
114 plays additional roles in human disease, its nuclear translocation mechanism remains unresolved.
115 f impaired SNAI1 proteasomal degradation and nuclear translocation, might be a sign of a diseased pro
117 ion, which enhances IkappaB degradation, p65 nuclear translocation, nuclear exit of MKL, and sequestr
118 ng a hypoxia-tracer, we show that HIF-1alpha nuclear translocation occurred both in hypoxic and non-h
119 ctivation, enhanced spine Ca(2+) transients, nuclear translocation of a CaM shuttle, and nuclear CaMK
120 chaperones have been shown to play a role in nuclear translocation of a variety of proteins including
121 Notably, FCHSD2 depletion results in the nuclear translocation of active extracellular signal-reg
122 n of glioblastoma stem-like cells drives the nuclear translocation of an intracellular fragment of OD
123 evented 5alpha- dihydrotestosterone-mediated nuclear translocation of AR and induced proteasomal degr
124 rt which otherwise dominates over import and nuclear translocation of AR as a transcription factor.
126 g of CD8(+) T cells induces a TNIK-dependent nuclear translocation of beta-catenin with consecutive W
127 endocytosis did not affect accumulation and nuclear translocation of beta-catenin, as measured by si
128 ling in the neoplastic epithelium to promote nuclear translocation of beta-catenin, cellular prolifer
130 ular activation of c-Jun was demonstrated by nuclear translocation of c-Jun, enhanced phosphorylation
132 nscription factor RelA was enhanced, whereas nuclear translocation of c-Rel was decreased in A20-defi
133 sclosed that Importin 4 (IPO4) augmented the nuclear translocation of CEBPD through nuclear localizat
134 ll line HuT78 activates the Notch pathway by nuclear translocation of cleaved Notch1 intracellular do
135 between CLOCK and BMAL1 and interferes with nuclear translocation of CLOCK both in vivo and in vitro
137 rzA, displayed normal alkaline tolerance and nuclear translocation of CrzA was unaffected by ambient
139 e found that BMP-2 stimulated expression and nuclear translocation of Dlx3 and Osx in odontoblasts bo
140 e ERK1/2-importin7 interaction, inhibits the nuclear translocation of ERK1/2, and arrests active ERK1
142 e of the hallmarks of the ERK cascade is the nuclear translocation of ERK1/2, which is important main
143 changes in the kinase domain that result in nuclear translocation of ERK5 and stimulation of gene tr
145 the LKB1-AMPK axis, thereby facilitating the nuclear translocation of FoxO1 and activation of key glu
146 eleases Gli2 from SuFu binding, resulting in nuclear translocation of Gli2 and transcription of parat
149 ing protein calmodulin (CaM), which leads to nuclear translocation of GRK5 and promotion of cardiac h
152 ich Vpx orchestrates the challenging task of nuclear translocation of HIV-2/SIV genome in nondividing
153 to rhinovirus and viral mimics and decreased nuclear translocation of interferon regulatory factors.
155 hermore, NS1 blocked the phosphorylation and nuclear translocation of IRF3 upon stimulation by variou
156 STING-mediated IFN production is mediated by nuclear translocation of IRF3 whereas TLR9-mediated acti
157 TAK1 and IKKbeta activation, leading to the nuclear translocation of IRF5 and induction of inflammat
160 tion signal (NLS) was inactivated to prevent nuclear translocation of nBMP2 while still allowing the
162 idinecarbonitrile) and IKK 16 prevented both nuclear translocation of NF-kappaB and activation of a N
163 to an inflammatory phenotype associated with nuclear translocation of NF-kappaB and production of IL-
164 Treatment with an A(2A)AR agonist decreased nuclear translocation of NF-kappaB and subsequent produc
165 h STING signalosomes and interferes with the nuclear translocation of NF-kappaB and the induction of
166 hronic antipsychotic drug exposure increases nuclear translocation of NF-kappaB in both mouse and hum
167 cFOS, STAT3, p38-MAPK, AKT and IKKs, and the nuclear translocation of NF-kappaB p-65 subunit whereas
170 iR-301a-mediated inhibition of NKRF enhances nuclear translocation of NF-kappaB, which, in turn, resu
173 Mechanistically, phenformin induces the nuclear translocation of NFATc1 in keratinocytes in an A
174 ation duration, the LV showed an increase in nuclear translocation of NFkappaB (p65), whereas the RV
175 exposure of PHH to HBV particles resulted in nuclear translocation of NFkappaB, followed by the expre
176 KKbeta phosphorylation but did not block the nuclear translocation of NFkappaB, which was surprising,
179 lays an important role in the activation and nuclear translocation of Notch intracellular domain (NIC
180 t maternal piRNAs, which prevents precocious nuclear translocation of NRDE-3 in the early embryo.
182 mic reticulum (ER) stress elicited prominent nuclear translocation of Nrf2 in 100% of HCV infected he
184 (ERK1/2), NF-kappaB, and Nrf2 activation and nuclear translocation of Nrf2, and it reduced the expres
185 malized the ER-stress response and prevented nuclear translocation of Nrf2, whereas HCV clearance by
186 increased reactive oxygen species and caused nuclear translocation of Nrf2, which in turn upregulated
188 Moreover, increased BMP signaling promoted nuclear translocation of nuclear factor-activated T-cell
189 ted mmp-3 promoter activity with concomitant nuclear translocation of nuclear factor-kappaB (NF-kappa
190 an increase in both the cellular content and nuclear translocation of p-S552 beta-catenin after 15 mi
192 enetic deficiency inhibits mitochondrial and nuclear translocation of p53 in cultured cells and in AP
193 alization in a p65-dependent fashion and the nuclear translocation of p65 as mediated through SETD1,
195 IkappaBalpha phosphorylation, and suppressed nuclear translocation of p65 in RAW264.7 cells induced b
198 lpha (IkappaBalpha) and p65 phosphorylation, nuclear translocation of p65, and regulation of target g
199 paBalpha and degradation of IkappaBalpha and nuclear translocation of p65, and suppressed basal level
200 ed activation of NF-kappaB via inhibition of nuclear translocation of p65-NFkappaB, the transcription
203 l molecules targeting the NFAT pathway alter nuclear translocation of PER and CRY proteins and impact
204 an cells, and we showed how the mobility and nuclear translocation of PER2 are regulated by casein ki
205 gnaling cascade, which, in turn, induces the nuclear translocation of phospho-Nrf2 protein to regulat
209 cells treated with IFN-alpha, it blocks the nuclear translocation of pSTAT1 by interacting with the
211 Akt activity mediates growth factor-induced nuclear translocation of Raptor, a regulatory scaffoldin
212 ) levels can be independently regulated, and nuclear translocation of receptor tyrosine kinases (RTKs
213 igase which dephosphorylates IkB and impedes nuclear translocation of RelA (p65), thus repressing onc
214 appaB activation, as shown by the absence of nuclear translocation of RelA with a decreased expressio
215 coholic liver disease, we detected increased nuclear translocation of RELB and increased levels of LT
216 duced BCR and NF-kappaB signaling, inhibited nuclear translocation of RelB and p50, and decreased Bcl
218 c study showed the inhibition of EGFR caused nuclear translocation of S6K1 for binding with MDM2 in r
221 ed by decreased STAT1/STAT2 phosphorylation, nuclear translocation of STAT1, and expression of IFN-al
222 aining revealed that the virus prevented the nuclear translocation of STAT2 molecules, confirming the
223 rance induction of monocytes associated with nuclear translocation of STAT3 and BCL-3 as relevant mec
227 ates Aqp2 transcription through induction of nuclear translocation of the acetyltransferase EP300, wh
228 d adrenal explant culture supernatant induce nuclear translocation of the androgen receptor in female
229 ditis elegans, mitochondrial damage leads to nuclear translocation of the ATFS-1 transcription factor
230 chanistically, this phenotype is ascribed to nuclear translocation of the basic helix-loop-helix tran
232 ification in RPE cells, which coincides with nuclear translocation of the lysosomal stress-sensing tr
234 of NF-kappaB inhibitor alpha in IECs led to nuclear translocation of the NF-kappaB subunit p65 and r
235 d extracellular signal-regulated kinase 1/2; nuclear translocation of the NF-kappaB subunit p65; and
236 e optimal IkappaB kinase phosphorylation and nuclear translocation of the nuclear factor kappa light
237 te precursor cells associated with increased nuclear translocation of the nuclear factor of activated
238 multipotent mesenchymal cells stimulated the nuclear translocation of the PC1 C-terminal tail/TAZ (PC
239 F-beta signaling via high-content imaging of nuclear translocation of the profibrotic transcription f
241 ing epithelial oxidative stress and inducing nuclear translocation of the signaling protein beta-cate
242 ut inhibiting IFN-induced phosphorylation or nuclear translocation of the STAT1 and STAT2 transcripti
243 no other tryptophan metabolite promotes the nuclear translocation of the transcription factor aryl h
245 ts antiretroviral responses by promoting the nuclear translocation of the transcription factor EB (TF
246 upregulate autophagic genes by inducing the nuclear translocation of the transcription factor EB (TF
247 complementation, triggers TCRs and activates nuclear translocation of the transcription factor nuclea
248 ssion through a conserved pathway leading to nuclear translocation of the transcriptional effector Yk
249 ated impaired S1P cleavage, which prohibited nuclear translocation of the transcriptionally active fo
250 sulting in distinct cellular trafficking and nuclear translocation of the virus compared to that in o
252 eneity, which was positively associated with nuclear translocation of the YAP/TAZ transcriptional co-
254 Rap and rapalogs induced autophagic flux via nuclear translocation of transcription factor EB (TFEB).
256 pro-inflammatory mediators and viral-induced nuclear translocation of transcription factors from Nucl
257 ch resulted in increased phosphorylation and nuclear translocation of transcription factors NFkappaB,
258 d stimulated them with TNFalpha and analyzed nuclear translocation of transcription regulators -NFkap
259 ncreased focal adhesion kinase signaling and nuclear translocation of transcriptional coactivator TAZ
261 (UPR) by interacting with and regulating the nuclear translocation of XBP-1s, a transcription factor
262 al rise in p38 phosphorylation activated the nuclear translocation of XBP1, which together with the t
265 d destabilized LATS and resulted in enhanced nuclear translocation of YAP and TAZ, accompanied with a
266 osine phosphorylation and strong, continuous nuclear translocation of YAP in ECs that is dependent on
267 ical constraints results in accumulation and nuclear translocation of Yap, which triggers proliferati
269 to elucidate the mechanism of regulation of nuclear translocation of Yes-associated protein (YAP) un
270 ore, elevated cAMP inhibited mitogen-induced nuclear-translocation of MKL1 and MKL2 in VSMCs but not
274 appaB transactivation, and delayed NF-kappaB nuclear translocation, presumably via delayed kinetics o
275 lamina that interferes with nucleokinesis, a nuclear translocation process required for neuronal migr
276 down ATF4 decreased NRF2 expression and its nuclear translocation, reduced HO-1 expression and incre
277 a cell-penetrating peptide that inhibits FUS nuclear translocation reduces FUS nuclear content and co
278 ally modulating PD-L1 acetylation blocks its nuclear translocation, reprograms the expression of immu
280 l site affecting protein phosphorylation and nuclear translocation, resulting in CVID with adrenocort
281 aling and STAT1 activation, it precluded the nuclear translocation specifically of STAT1 in response
282 escent phenotype, correlating with NF-kappaB nuclear translocation, suggesting a mechanism of toleran
283 ependent transactivation ability and altered nuclear translocation, suggesting abnormal interactions
285 ownregulation of NFKBIB by siRNA led to RELA nuclear translocation that could bind to the KIT promote
286 ) by inhibiting NF-kappaB activation and its nuclear translocation (the root cause for inflammation i
287 thesis, or hypoxia) also triggers SnRK1alpha nuclear translocation, thereby controlling induced but n
289 athways of the target cell and mediate their nuclear translocation through components of the nuclear
290 hat photoluminescent Pdots provide selective nuclear translocation to hepatocellular carcinoma cells
291 esenchymal transition (EMT) and beta-catenin nuclear translocation to promote cell migration and inva
293 tivated T cells 1 (NFATc1) and regulates its nuclear translocation via interaction with Ppia, and thi
297 iated YAP1 dephosphorylation and promote its nuclear translocation which induces a pro-survival gene
298 lly, CD82 modulates TLR9-dependent NF-kappaB nuclear translocation, which is critical for inflammator
299 disrupts TFEB phosphorylation, allowing its nuclear translocation, which is synergized by increased
300 ed-forward activates TFEB via promoting TFEB nuclear translocation, while bile acid-induced fibroblas