ライフサイエンスコーパス: nucleophilic substitution

1 y produced secondary Cl isotope effects (via nucleophilic substitution).

2 itution reactions of SNAr and VNS (vicarious nucleophilic substitution).

3 hore via Ru-catalyzed cross-metathesis and a nucleophilic substitution.

4 n follows base-dependent normal and abnormal nucleophilic substitution.

5 -quinone methide, followed by intramolecular nucleophilic substitution.

6 n intermolecular condensation/intramolecular nucleophilic substitution.

7 r the insertion of more complex moieties via nucleophilic substitution.

8 ative cycloetherification, and (iv) aromatic nucleophilic substitution.

9 olvents in both an aliphatic and an aromatic nucleophilic substitution.

10 m their corresponding mesylate precursors by nucleophilic substitution.

11 iamines, amine elimination by intramolecular nucleophilic substitution.

12 e charge of C1' and, hence, accelerating the nucleophilic substitution.

13 ox cross-coupling followed by intramolecular nucleophilic substitution.

14 thways, a concerted E2 elimination and a SN2 nucleophilic substitution.

15 eophiles with polyfluoroarenes activated for nucleophilic substitution.

16 enter is asymmetric, poised for dissociative nucleophilic substitution.

17 atoms displaced from DTAF in alkaline pH via nucleophilic substitution.

18 benzisoxazole products via an intramolecular nucleophilic substitution.

19 ion at position 6 through cross-couplings or nucleophilic substitutions.

20 /- 0.04, respectively, which are typical for nucleophilic substitutions.

21 cids can act as cofactors for cage-catalyzed nucleophilic substitutions.

22 sm of catalysis consisting of two subsequent nucleophilic substitutions.

23 The competition between bimolecular nucleophilic substitution and base-induced elimination i

24 012-1.002 and 1.0021-1.004 were observed for nucleophilic substitution and dibromoelimination, respec

25 odeling have been used to characterize their nucleophilic substitution and elimination reactions.

26 on-carbon bonds, and the competition between nucleophilic substitution and elimination.

27 from charge transfer and proton transfer to nucleophilic substitution and elimination.

28 Both nucleophilic substitution and reductive dechlorination a

29 2-yl)diphenylmethanol (2) featuring a double nucleophilic substitution and Shi epoxidation as key ste

30 r termination reactions of NDIBr end groups: nucleophilic substitution and solvent end-capping by aro

31 by hydroxylation, may have a higher yield of nucleophilic substitution and subsequent NDMA formation

32 of acetochlor and S-metolachlor to occur via nucleophilic substitution and the predominance of oxalin

33 The products are readily elaborated both by nucleophilic substitution and through transition-metal-c

34 ming reactions through iminium catalysis, in nucleophilic substitutions and additions through enamine

35 gaged in nucleophilic substitution, aromatic nucleophilic substitution, and Pd-catalyzed cross-coupli

36 lecular nucleophilic addition," "Bimolecular nucleophilic substitution," and "Unimolecular eliminatio

37 This general and expeditious MW-enhanced nucleophilic substitution approach uses easily accessibl

38 obtained by this methodology were engaged in nucleophilic substitution, aromatic nucleophilic substit

39 Successful nucleophilic substitution at a methylene attached to the

40 oisomerase (vTopo) catalyzes highly specific nucleophilic substitution at a single phosphodiester lin

41 opoisomerase that shows high specificity for nucleophilic substitution at a single phosphodiester lin

42 polysulfides (R-S(n)-R'; n > 2) also undergo nucleophilic substitution at a sulfur atom, yielding RS(

43 The reaction is a formal stereoretentive nucleophilic substitution at an oxygenated tertiary carb

44 The reaction, formally a nucleophilic substitution at an sp(2) carbon atom, allow

45 tudies suggest that the reaction, formally a nucleophilic substitution at an sp(2) carbon atom, proce

46 ntramolecular cyclization reaction through a nucleophilic substitution at C-5 or C-6 of C-glycosides

47 alpha-D-mannose to GDP and the beta-sugar by nucleophilic substitution at carbon rather than at phosp

48 udix enzymes studied so far, GDPMH catalyzes nucleophilic substitution at carbon rather than at phosp

49 eory (DFT)-computed barriers for bimolecular nucleophilic substitution at methyl derivatives (S(N)2@C

50 Although stereospecific nucleophilic substitution at P(V) provides a general str

51 ynucleoside-triphosphate (NTP) substrates by nucleophilic substitution at Pbeta, to yield a nucleotid

52 he hydrolysis of nucleoside triphosphates by nucleophilic substitution at Pbeta, to yield the nucleot

53 sis of nucleoside diphosphate derivatives by nucleophilic substitution at phosphorus.

54 nzyl-2-azabicyclo[2.2.1]heptane allows ready nucleophilic substitution at the 7-position by C, N, O,

55 Allyl-substituted polysulfides undergo nucleophilic substitution at the alpha carbon of the all

56 attention for the insight they provide into nucleophilic substitution at the hindered anomeric cente

57 ion are restricted to coupling reactions and nucleophilic substitution at the meso position in the ch

58 vatives undergo a regio- and stereoselective nucleophilic substitution at the quaternary carbon cente

59 side triphosphates (NTP) to NMP and PP(i) by nucleophilic substitution at the rarely attacked beta-ph

60 1,3-Dihydro-1,3-azaborines also undergo nucleophilic substitutions at boron and electrophilic ar

61 owed by glycosylation and cross-couplings or nucleophilic substitutions at position 4.

62 In excess of monochloramine, nucleophilic substitution between ranitidine and monochl

63 nti-IL2, where fluoro group of FNP undergoes nucleophilic substitution by amino group of biomolecule

64 For CH(3)Cl only nucleophilic substitution by H(2)O was observed at signi

65 ant carbon isotope effects were observed for nucleophilic substitution by HS(-) (epsilon = -31.6 +/-

66 in these reactions, lowering the barrier for nucleophilic substitution by more than 20 kcal/mol relat

67 The reactivity of 11 with respect to nucleophilic substitution by O-, N-, and S-nucleophiles

68 ated by reductive B-elimination, followed by nucleophilic substitution by surface-bound sulfur nucleo

69 P-alpha-D-hexose to GDP and beta-D-hexose by nucleophilic substitution by water at C1 of the sugar.

70 carbon-carbon bonds, allylic and propargylic nucleophilic substitutions, C-H activation reactions, cr

71 Although the regioselectivity of nucleophilic substitution can be affected by the nature

72 using amidation and intramolecular aromatic nucleophilic substitution chemistry.

73 A one-pot tandem Staudinger/intramolecular nucleophilic substitution converts 8 into 2'-amino-alpha

74 est that this reaction proceeds via aromatic nucleophilic substitution driven by the superacidic natu

75 Sequencing a free radical addition and nucleophilic substitution enables [3 + 2] and [4 + 2] an

76 ysts, and preliminary studies on a classical nucleophilic substitution established that they each gav

77 for an S(N)2 pathway for the intramolecular nucleophilic substitution event.

78 bond-forming step proceeds in a bimolecular nucleophilic substitution fashion.

79 lyl alcohol and tert-butyl mercaptan undergo nucleophilic substitution followed by 5-exo-trig radical

80 The new method involves an intermolecular nucleophilic substitution followed by intramolecular 1,2

81 ge of C-C bonds (extradiol dioxygenase), and nucleophilic substitutions (fosfomycin resistance protei

82 loaddition (Click reaction) was installed by nucleophilic substitution from a bromide precursor.

83 plicity, the concerted S(N)2 thiol-disulfide nucleophilic substitution has been successfully used as

84 s of 1-alkyl-5-((di)alkylamino)tetrazoles by nucleophilic substitution in 1-alkyl-5-sulfonyltetrazole

85 An alternative approach based on nucleophilic substitution in 5-bromomethyl derivatives w

86 at boranephosphonate diesters undergo facile nucleophilic substitution in a stereospecific manner upo

87 correct and complete mechanistic picture of nucleophilic substitution in nitroarenes based on the re

88 suggests that the reaction occurred by S(N)2 nucleophilic substitution, in which the chlorine was rep

89 osed rationale for the retention pathway for nucleophilic substitution involves CO-coordination to fo

90 the few reported examples of stereospecific nucleophilic substitution involving chiral bridged carbo

91 te), the reaction proceeds with the abnormal nucleophilic substitution irrespective of the base and w

92 Bimolecular nucleophilic substitution is one of the fundamental reac

93 the electrodeposited polymer membrane after nucleophilic substitution is presented.

94 The SN2 reaction (bimolecular nucleophilic substitution) is a well-known chemical tran

95 h H2 but leads instead to side products from nucleophilic substitution (k = 4 x 10(-2) L mol (-1) s(-

96 Concerted nucleophilic substitution, known as S(N)2 reaction, is a

97 re of cis and trans isomers and (2) a direct nucleophilic substitution leading to a stereoselective s

98 silver-induced reaction mostly consists of a nucleophilic substitution, leading to polystyrene molecu

99 These structures support an internal nucleophilic substitution-like mechanism, lend new mecha

100 ound to the enzyme, enabling us to propose a nucleophilic substitution mechanism for this biological

101 es indicate that the reaction proceeds via a nucleophilic substitution mechanism involving allyl copp

102 Based on the present experimental results, a nucleophilic substitution mechanism is proposed for the

103 Control studies support a concerted nucleophilic substitution mechanism that proceeds in the

104 substrates have assumed a classical in-line nucleophilic substitution mechanism, in which the 3'-hyd

105 DFT calculations support a concerted nucleophilic substitution mechanism, where anion coordin

106 uctures also suggest a plausible single-step nucleophilic substitution mechanism.

107 pairs per repeating unit are synthesized by nucleophilic-substitution-mediated polymerization or rad

108 AVT-011 was labeled with (18)F using the nucleophilic substitution method, and a standard set of

109 ystems can be readily accessed by sequential nucleophilic substitution methodology which may have app

110 -1,4-diketones has been established from the nucleophilic substitution of 2-bromoacetophenones with N

111 Nucleophilic substitution of 2beta-mesyloxymethyl-N-meth

112 thesized in good to excellent yields via the nucleophilic substitution of 5-(benzotriazol-1-yl)-1-sub

113 ivatives were synthesized through sequential nucleophilic substitution of [(eta(5)-cyclopentadienyl)(

114 The method relies on nucleophilic substitution of a chiral phosphinate derive

115 -L-phenylalanine ((18)F-DOPA), involving the nucleophilic substitution of a diaryliodonium salt precu

116 ine that afforded the (3R*,4S*)-form and the nucleophilic substitution of a fluoroarene with deproton

117 re used as fluoride-binding reagents for the nucleophilic substitution of a model alkyl bromide.

118 have been synthesized for the first time by nucleophilic substitution of a protected aminomalonate o

119 or catalytic phosphorus-based activation and nucleophilic substitution of alcohols has been validated

120 transformations in organic chemistry is the nucleophilic substitution of alcohols.

121 Although the nucleophilic substitution of alkyl halides by azide is p

122 and deutero benzene at 60 degrees C through nucleophilic substitution of an aromatic C-D/H bond.

123 ctionalize aryl methyl ethers through direct nucleophilic substitution of aryl C-OMe bond has been de

124 the synthesis of N-azine sulfoximines by the nucleophilic substitution of azine N-oxides with NH-sulf

125 A highly diastereoselective formal nucleophilic substitution of bromocyclopropanes with oxy

126 ioyl)oxy (oxa)helicenes in a flow reactor or nucleophilic substitution of dichloro (oxa)helicenes wit

127 zation of the thioacetic acid derivative via nucleophilic substitution of halogen in the aromatic rin

128 rmation of 5-indolyl-3-yl derivatives, while nucleophilic substitution of hydrogen (S(N)(H)) at C(5)

129 Methodology of nucleophilic substitution of hydrogen (S(N)(H)) was firs

130 F-05270430 was radiolabeled by 2 methods via nucleophilic substitution of its tosylate precursor.

131 RPHOS/dmpe catalyst (11) was optimal for the nucleophilic substitution of less activated alkyl bromid

132 rane reagents by proton transfer followed by nucleophilic substitution of methanol at the boron atom

133 ts formation has commonly been attributed to nucleophilic substitution of N2 in a guaninediazonium io

134 The nucleophilic substitution of N2 in benzenediazonium ion

135 inary mechanistic studies reveal the initial nucleophilic substitution of QMAs with 2-naphthols in pr

136 talyst components) for the enantioconvergent nucleophilic substitution of racemic secondary alkyl hal

137 Nucleophilic substitution of tetrabromosubstituted napht

138 th sodium diselenide provided 6 via aromatic nucleophilic substitution of the 2-bromo substituent.

139 Nucleophilic substitution of the annulation products and

140 zotriazole and formaldehyde, followed by the nucleophilic substitution of the benzotriazolyl group wi

141 Nucleophilic substitution of the chlorine atom in acivic

142 The fluorine-18 analogue was prepared via nucleophilic substitution of the corresponding tosylate

143 olecular cyclization of these thioamides via nucleophilic substitution of the halogen on the aromatic

144 Subsequent nucleophilic substitution of the omega-bromo groups with

145 stion addressed in this paper is whether the nucleophilic substitution of the p-nitrophenoxy group in

146 ation of o-arylacetophenone, (ii) sequential nucleophilic substitution of the resulting alpha-bromo o

147 e (TAPP) derivatives were obtained by direct nucleophilic substitution of the tetrabrominated TAPP or

148 Synthesis of the latter involved nucleophilic substitution of tosyl group in readily avai

149 ggests that the forward reaction is mainly a nucleophilic substitution of type 2 (S(N)2) with a mix o

150 electron acceptors have been synthesized by nucleophilic substitutions of 2,6-dichloropyrazine with

151 Nucleophilic substitutions of 3 with Grignard reagents,

152 Nucleophilic substitutions of C-3 and C-4 alkyl-substitu

153 propanol, promoting low-temperature aromatic nucleophilic substitutions of chloroheteroarenes, has be

154 te from S(N)1 stereoelectronic models in the nucleophilic substitutions of tetrahydropyran acetals we

155 Nucleophilic substitutions of the benzene ring proceed w

156 Subsequent nucleophilic substitutions of the benzotriazole group in

157 Nucleophilic substitutions of the benzotriazolyl group i

158 So far, classic peptide coupling, nucleophilic substitution, olefin metathesis, and click

159 The nucleophilic substitution on 3-substituted 2-methoxytrop

160 ly regio- and stereoselective manner through nucleophilic substitution on a cyclic sulfate.

161 contrast, the corresponding stereoinvertive nucleophilic substitution on electronically unbiased sp(

162 ate a third reactivity profile of the anion, nucleophilic substitution on heavier halides of group 14

163 The method relies on sequential nucleophilic substitution on the versatile chiral phosph

164 The geometries of the transition states for nucleophilic substitutions on benzyl-silane and -germane

165 Nucleophilic substitution or reductive methylation affor

166 Its nucleophilic substitutions or cross-coupling reactions a

167 e of substrate C-Cl, P-C, and P-OP bonds via nucleophilic substitution pathways.

168 nium salts can be further functionalized via nucleophilic substitution, photoredox coupling, and elec

169 isomerization, leading to an intramolecular nucleophilic substitution process at silicon, and 1,5-si

170 achieved via an unexpected, stereoconvergent nucleophilic substitution process, wherein two diastereo

171 creating silicon-centered chirality during a nucleophilic substitution process.

172 ent with a base to promote an intramolecular nucleophilic substitution process.

173 ether: A general synthetic strategy based on nucleophilic substitution provided B-substituted 1,3-dih

174 ]FAMP and [18F]N-MeFAMP via no-carrier-added nucleophilic substitution provided high yields (>78% dec

175 ich scaffolds through transformation such as nucleophilic substitution, radical addition reactions an

176 imetallic complex catalytically promotes the nucleophilic substitution reaction (here after alpha-ami

177 ith 2-SH-benzazoles and after intramolecular nucleophilic substitution reaction and electrooxidative

178 The nucleophilic substitution reaction at sulfur follows the

179 The first step involves a nucleophilic substitution reaction between aryl-BF3K sal

180 We discovered that the nucleophilic substitution reaction between carboxylate a

181 key step in the synthesis is a new vicarious nucleophilic substitution reaction between p-nitroanisol

182 transferase type I (PGGTase-I) catalyzes the nucleophilic substitution reaction between the C(20) ger

183 The prodrug synthesis involves a nucleophilic substitution reaction between the parent te

184 The reversible nucleophilic substitution reaction catalyzed by the vacc

185 The highly exoergic nucleophilic substitution reaction F(-) + CH3I shows rea

186 duction enlisted a room-temperature aromatic nucleophilic substitution reaction for formation of the

187 entially features an intramolecular aromatic nucleophilic substitution reaction for formation of the

188 left-hand ring system enlisting an aromatic nucleophilic substitution reaction for macrocyclization

189 onstrated through application to a classical nucleophilic substitution reaction for the study of solv

190 The vicarious nucleophilic substitution reaction has also been extende

191 urea-mediated phospha-Mannich/intramolecular nucleophilic substitution reaction has been developed fo

192 d allenes via phospha-Michael/intramolecular nucleophilic substitution reaction has been developed.

193 3-nitro-1,2-diphenylcyclopropene undergoes a nucleophilic substitution reaction in alcohols and thiol

194 en developed from skipped enynes by a direct nucleophilic substitution reaction in HFIP at room tempe

195 mild and highly effective catalyst for this nucleophilic substitution reaction in which N-methyl-2-p

196 y to reverse the stereochemical outcome of a nucleophilic substitution reaction is unprecedented in t

197 e low reactivity of anilines in the aromatic nucleophilic substitution reaction leading to the format

198 The intramolecular nucleophilic substitution reaction of 3-oxo-2-(2'-pyridy

199 banions generated via base-induced vicarious nucleophilic substitution reaction of alkyl dichloroacet

200 e syn-connectivity based on a regioselective nucleophilic substitution reaction of Br4-NDI with aryla

201 een clearly demonstrated on the basis of the nucleophilic substitution reaction of CN(-) on (5F)LOH.

202 The nucleophilic substitution reaction of Cys-SeH on (NO2)L

203 QM/MM potential to study the dynamics of the nucleophilic substitution reaction of dichloroethane by

204 as well as by monitoring the kinetics of the nucleophilic substitution reaction of the imidazole moie

205 Aromatic nucleophilic substitution reaction of the nitro group of

206 ne-thiourea in the sequential intramolecular nucleophilic substitution reaction of the phosphonylatio

207 The rate of the nucleophilic substitution reaction of tributylamine with

208 ined from alkyl bromides and tosylates via a nucleophilic substitution reaction or by hydrothiolation

209 %) and diastereoselective (>/=15:1) aromatic nucleophilic substitution reaction that benefits from su

210 phine derivatives undergo the intramolecular nucleophilic substitution reaction upon treatment with a

211 Alternatively, the oxirane undergoes a nucleophilic substitution reaction where the conjugate b

212 talyzed by SET7/9 is a typical in-line S(N)2 nucleophilic substitution reaction with a transition sta

213 6-Cyanouracil derivatives underwent a direct nucleophilic substitution reaction with alkyl Grignard r

214 Mesylation of the diol followed by double nucleophilic substitution reaction with primary amines l

215 Each enzyme catalyzes a nucleophilic substitution reaction, but IS and SS are un

216 l halide serves as a "textbook example" of a nucleophilic substitution reaction, the selective mono-a

217 hanisms of the OH- + CH3F --> CH3OH + F- SN2 nucleophilic substitution reaction.

218 were radiolabeled with (18)F using aromatic nucleophilic substitution reaction.

219 Radiolabeling was accomplished by a nucleophilic substitution reaction.

220 eotide was assumed to be a classical in-line nucleophilic-substitution reaction in which the 3'-hydro

221 types of alkylating agents defined by their nucleophilic substitution reactions (SN1 and SN2) are st

222 Bimolecular nucleophilic substitution reactions at allylic systems,

223 A series of gas-phase nucleophilic substitution reactions at sulfur of methane

224 are shown to be activated to stereospecific nucleophilic substitution reactions by precisely tailore

225 sulfonium ion is provided, as are data from nucleophilic substitution reactions demonstrating that p

226 ructure, the approach relied on two aromatic nucleophilic substitution reactions for formation of the

227 such as the remarkably lower reactivities in nucleophilic substitution reactions in protic solvents t

228 A series of nucleophilic substitution reactions involving simple spe

229 suggesting that the diastereoselectivity of nucleophilic substitution reactions is attenuated at the

230 owed by the 3,5- and then the 2,6-positions; nucleophilic substitution reactions occur first at the 8

231 Nucleophilic substitution reactions of 2-deoxyglycosyl d

232 Nucleophilic substitution reactions of 4-substituted cyc

233 Nucleophilic substitution reactions of acetals having be

234 Nucleophilic substitution reactions of alcohols are amon

235 Catalytic enantioconvergent nucleophilic substitution reactions of alkyl halides are

236 Nucleophilic substitution reactions of C-4 sulfur-substi

237 on the S(N)1, S(N)2, and syn and anti S(N)2' nucleophilic substitution reactions of chloride anion wi

238 onic models in assessing the stereoselective nucleophilic substitution reactions of cyclic oxocarbeni

239 specially designed phosphine oxide promotes nucleophilic substitution reactions of primary and secon

240 Nucleophilic substitution reactions of small rings incor

241 Lewis acid-mediated nucleophilic substitution reactions of substituted tetra

242 , efficiently promoted intramolecular direct nucleophilic substitution reactions of unsaturated alcoh

243 e triazole as an effective LG for activating nucleophilic substitution reactions on tyrosine sites of

244 this type are not sufficiently activated for nucleophilic substitution reactions that are generally r

245 shown to catalyze a variety of dissociative nucleophilic substitution reactions that proceed via oxo

246 ups allows for further functionalization via nucleophilic substitution reactions to generate new full

247 ition-metal catalysis to expand the scope of nucleophilic substitution reactions to include carbon nu

248 of a masked alcohol and subsequently employs nucleophilic substitution reactions to prepare various d

249 Control experiments confirmed that all nucleophilic substitution reactions were performed under

250 lonate react with lithiated alcohols through nucleophilic substitution reactions where azide acts as

251 lic bromides that are crosslinked in situ by nucleophilic substitution reactions with carboxylates.

252 Through nucleophilic substitution reactions, the chlorides are u

253 nsic gas-phase reactivity and selectivity of nucleophilic substitution reactions.

254 a common reagent for substrate activation in nucleophilic substitution reactions.

255 phane are extremely reactive with respect to nucleophilic substitution reactions.

256 stants and diastereoselectivity results from nucleophilic substitution reactions.

257 ubstituents have on the stereoselectivity of nucleophilic substitution reactions.

258 and n-hexyl iodide as electrophiles in model nucleophilic substitution reactions.

259 which mirror classical SN1 and SN2 models of nucleophilic substitution reactions.

260 itroarenes, such as reductions and vicarious nucleophilic substitution reactions.

261 S of disulfide bond reduction, a bimolecular nucleophilic substitution (S N2) reaction.

262 on between two classical organic mechanisms, nucleophilic substitution (S(N)2) and base-induced elimi

263 yzed the competition between the bimolecular nucleophilic substitution (S(N)2) and base-induced elimi

264 Bimolecular nucleophilic substitution (S(N)2) mechanisms occupy a ce

265 are presented for the bimolecular gas-phase nucleophilic substitution (S(N)2) reaction Cl(-) + CH(3)

266 aromatic substitution (S(N)Ar)/second-order nucleophilic substitution (S(N)2) reaction to give spiro

267 Based on the halogenophilic nucleophilic substitution (S(N)2X) process, this new bas

268 pite the substantial advances in bimolecular nucleophilic substitutions (S(N)2) at saturated carbon c

269 as introduced by an NBS-mediated bromination-nucleophilic substitution sequence.

270 adical addition (ATRA) and an intramolecular nucleophilic substitution (SN) process is proposed to oc

271 ion, and transfer of pyrophosphate through a nucleophilic substitution (SN2) reaction.

272 nation through dynamic water channels, and a nucleophilic substitution (SN2) transition state for tra

273 labeling of arenes not amenable to aromatic nucleophilic substitution (SNAr) with [(18)F]F(-).

274 le cyclization as a result of intermolecular nucleophilic substitution (SNAr).

275 ng functional groups that are susceptible to nucleophilic substitution such as alkyl halides.

276 Also, the initial kinetic profiling for the nucleophilic substitution supports an SN1-like (SN2C+) m

277 tetramethylethylenediamine was followed by a nucleophilic substitution that successfully reversed the

278 nitrogen heterocyclic groups are amenable to nucleophilic substitution, the goal of this study was th

279 on studies are described for bimolecular SN2 nucleophilic substitution, unimolecular decomposition, p

280 /SNAr procedure was performed to achieve C-2 nucleophilic substitution using several amine types.

281 addition/reductive elimination mechanism or nucleophilic substitution via a halogen "ate" intermedia

282 5-nitroisoquinoline, utilizing the vicarious nucleophilic substitution (VNS) as a key step, is descri

283 ntermediate anion derived from the vicarious nucleophilic substitution (VNS) of hydrogen reacts with

284 onamides from sulfonyl azides and amines via nucleophilic substitution was also developed.

285 matic Heck cross-coupling and N-pyridin-2-yl nucleophilic substitution was described.

286 ransformation of Ugi four-component reaction/nucleophilic substitution was developed for the synthesi

287 romolecules formed when the silver-catalyzed nucleophilic substitution was performed in methanol were

288 Several electrophilic and nucleophilic substitutions were also carried out.

289 anic diimide (MDI), that is shown to undergo nucleophilic substitution with a variety of ortho disubs

290 a Lewis acid and a biocatalyst, followed by nucleophilic substitution with amines and reduction.

291 CNBT end groups was synthesized by a sixfold nucleophilic substitution with cyanide on a fluorinated

292 roposed as an intermediate which undergoes a nucleophilic substitution with cysteine.

293 lpha-D-glucose is beta-D-glucose, indicating nucleophilic substitution with inversion at C1' of gluco

294 yzes the hydrolysis of GDP-alpha-d-sugars by nucleophilic substitution with inversion at the anomeric

295 -sugars to yield the beta-D-sugar and GDP by nucleophilic substitution with inversion at the C1' carb

296 esis of both (18)F-fluspidine enantiomers by nucleophilic substitution with K-(18)F-F-Kryptofix 222-c

297 phorodichloridate undergoes enantioselective nucleophilic substitution with phenols at ambient temper

298 o the mechanism and transition states of the nucleophilic substitutions with the neutral nucleophiles

299 This allylic nucleophilic substitution works well with primary and se

300 bstituted p-carboranes I, which upon further nucleophilic substitution yield p-carboranes II.