ライフサイエンスコーパス: nucleoprotein

1 capsid, but also acts as a chaperone for the nucleoprotein.

2 ssays targeting Ebola virus glycoprotein and nucleoprotein.

3 AM134B resulted in 80% of cells positive for nucleoprotein.

4 Ebola virus proteins, most notably the viral nucleoprotein.

5 senger RNA that encodes Marburg virus (MARV) nucleoprotein.

6 including neuraminidase, matrix protein 2 or nucleoprotein.

7 odies primarily recognized spike protein and nucleoprotein.

8 by the viral polymerase and oligomeric viral nucleoprotein.

9 ural protein with a Zinc-Finger domain and a nucleoprotein.

10 ts, the viral polymerase, and multiple viral nucleoproteins.

11 VHHs uniquely specific for their respective nucleoproteins.

12 t peptides belonging to the viral matrix and nucleoproteins.

13 of autoantibodies against nucleic acids and nucleoproteins.

14 t after, infection reduced the percentage of nucleoprotein 1-positive cells by 85, 56, and 66%, respe

15 on levels were measured by the percentage of nucleoprotein 1-positive cells using flow cytometry.

16 ike domains from PRX and its homologue AHNAK nucleoprotein 2 (AHNAK2).

17 Using hemagglutinin and nucleoprotein Ag-specific B cell tetramers and intracell

18 ted packaging sequence with sets of specific nucleoprotein amino acid substitutions greatly impairs t

19 e to each RNA segment together with specific nucleoprotein amino acids are thought to ensure the prec

20 enza A virus (FLUAV) are encapsidated by the nucleoprotein and associated with RNA polymerase, posing

21 ecognized by the respiratory syncytial virus nucleoprotein and compatible with weak interactions requ

22 ed lower affinity of 627E-containing PB2 for nucleoprotein and is increased by further nucleocapsid i

23 Notably, the rapid accumulation of viral nucleoprotein and matrix (M) gene RNA in chicken and duc

24 of Ab responses to SARS-CoV-2 spike (S) and nucleoprotein and nAb titers correlate with clinical sco

25 her RdRP subunits (PB1 and PA) and the viral nucleoprotein and neuraminidase, as well as 171 cellular

26 al studies on isolated DNA, polynucleotides, nucleoprotein and nucleohistone complexes.

27 e-sense RNA genomes that are encapsidated by nucleoprotein and other viral proteins to form a helical

28 M) protein gene is identical to those of the nucleoprotein and phosphoprotein genes except that it co

29 can utilize its viral proteins, such as the nucleoprotein and phosphorylation protein, to subvert th

30 tantial cross-reactivity for binding to LASV nucleoprotein and two engineered (linked and prefusion)

31 virus replication by directly targeting IAV nucleoproteins and disrupting virus ribonucleoprotein ex

32 g the simultaneous presence of antibodies to nucleoproteins and glycoproteins to define positivity, w

33 sive human protein interactome of arenavirus nucleoproteins and uncovers a potent antiviral host prot

34 ides (four from spike protein and three from nucleoprotein) and the top three to four transitions, wa

35 tic diversity in the viral hemagglutinin and nucleoprotein, and (iii) intrahost viral evolution conti

36 l studies of oligomerized, RNA-encapsidating nucleoprotein, and cryo-electron microscopy of nucleocap

37 n (H3 numbering), I109T in the gene encoding nucleoprotein, and T10I in the gene encoding neuraminida

38 detection of viral RNA and induction of anti-nucleoprotein antibodies after SARS-CoV-2 challenge.

39 es in ALT cancer cells exhibit a distinctive nucleoprotein architecture shaped by the mismanagement o

40 ling during spermiogenesis is not limited to nucleoproteins as part of the nucleoprotein exchange.

41 rt a hollow vesicle-like condensate phase of nucleoprotein assemblies that is distinct from RNA-prote

42 Retroviral integrase forms a higher order nucleoprotein assembly (intasome) to catalyze the integr

43 d by the virally encoded IN protein within a nucleoprotein assembly called an intasome.

44 The HIV intasome is a large nucleoprotein assembly that mediates the integration of

45 ing with DnaB then translocating away to aid nucleoprotein barrier removal ahead of the fork, another

46 sory helicases promote fork movement through nucleoprotein barriers and exist in viruses, bacteria an

47 DNA replication must cope with nucleoprotein barriers that impair efficient replisome t

48 tial roles in replication in the presence of nucleoprotein barriers, but how they operate inside the

49 whereas MDA5 and LGP2 specifically bound MV nucleoprotein-coding region.

50 eeded for molecular assembly of a high-order nucleoprotein complex and for ParB spreading.

51 partitioning mechanism, ParB proteins form a nucleoprotein complex at parS sites.

52 The intasome, a higher-order nucleoprotein complex composed of viral integrase (IN) a

53 Transposition requires the assembly of a nucleoprotein complex containing all four Tns proteins a

54 some of the models proposed in H-NS-mediated nucleoprotein complex formation.

55 ranscription and in the establishment of the nucleoprotein complex formed at telomeres.

56 ntributes to the formation of the beta-clamp nucleoprotein complex on origin DNA.

57 The structure of this post-transposition nucleoprotein complex reveals that the terminal single-s

58 suggest that a specific DNA geometry of the nucleoprotein complex stabilized on concomitant binding

59 able double-strand breaks and form an active nucleoprotein complex that can nick DNA substrates in tr

60 nals and the DNA is the chromatin, a dynamic nucleoprotein complex that helps to mediate gene regulat

61 Chromatin is the nucleoprotein complex that protects and compacts eukaryo

62 integrase (IN) functions within the intasome nucleoprotein complex to catalyze insertion of viral DNA

63 rB dimers tetramerize to form a higher order nucleoprotein complex.

64 th the protein and DNA components of a large nucleoprotein complex.

65 ules are tightly compacted into a dynamic 3D nucleoprotein complex.

66 ted for knowledge-based design of long-range nucleoprotein complexes and purposeful manipulation of t

67 inspires speculation about the links between nucleoprotein complexes and the origins of viruses.

68 croscopic interactions between or throughout nucleoprotein complexes by microscopically altering wrap

69 and observed intramolecular condensation of nucleoprotein complexes exceeding expectations based on

70 eaction chemistries and architectures of the nucleoprotein complexes involved.

71 y improves the solubility of the protein and nucleoprotein complexes of IN with viral DNA ends (intas

72 al assays, we explored the formation of H-NS nucleoprotein complexes on circular DNA molecules having

73 portant function in serving as a hub to form nucleoprotein complexes on DNA and RNA.

74 t the same way that RecBCD disrupts isolated nucleoprotein complexes on otherwise naked DNA.

75 h the formation of large membrane-associated nucleoprotein complexes physically occludes assembly of

76 essed quorum sensing loci by disrupting H-NS nucleoprotein complexes that block transcription.

77 nd Fis to assemble two distinct, very large, nucleoprotein complexes that carry out either integrativ

78 Telomeres are specialized nucleoprotein complexes that comprise the ends of linear

79 e novel ATMSI4-associated proteins help form nucleoprotein complexes that determine pleiotropic funct

80 Telomeres are nucleoprotein complexes that protect the ends of linear

81 Telomeres are nucleoprotein complexes that reside at the ends of linea

82 equired for processing protein substrates in nucleoprotein complexes, and that Lon may help regulate

83 h as DNA-protein crosslinks (DPCs) and tight nucleoprotein complexes, can block replication forks.

84 s helix is weak and requires the assembly of nucleoprotein complexes, thus establishing a mechanism f

85 e the structural dynamics of DNA and diverse nucleoprotein complexes.

86 ith the formation of larger, poorly defined, nucleoprotein complexes.

87 ring structures that constrict around viral nucleoprotein complexes.

88 structural dynamics and mechanochemistry in nucleoprotein complexes.

89 tes and chemotherapeutics, as well as stable nucleoprotein complexes.

90 ids to the physical remodeling or removal of nucleoprotein complexes.

91 ase assembled into two functionally distinct nucleoprotein complexes; the maturation complex and the

92 uctures including forked ssDNA overhangs and nucleoprotein conjugates.

93 om the disordered carboxy-terminal region of nucleoprotein-core links nucleoprotein oligomerization,

94 iferase, or influenza virus hemagglutinin or nucleoprotein) could decrease, while the RepRNA structur

95 ry for the detection of SARS-CoV-2 spike and nucleoprotein detection was approximately 2 x 10(5) vira

96 t differences in the polymerase proteins and nucleoprotein determined the altered virulence.

97 one antibody had the capacity to capture the nucleoprotein directly in lysis buffer used for releasin

98 generated against SARS-CoV spike protein and nucleoprotein, double stranded RNA, and RNA probe for sp

99 ggering range of functions from transport to nucleoprotein dynamics.

100 role in EBOV transcription initiation at the nucleoprotein (eNP) gene, with additional roles in the r

101 (+) T cell response to an H-2D(b)-restricted nucleoprotein epitope (NP366) is characterized by prefer

102 not limited to nucleoproteins as part of the nucleoprotein exchange.

103 human RAD51 (HsRAD51) recombinase can form a nucleoprotein filament (NPF) on double-stranded DNA (dsD

104 A when bound to single-stranded (ss)DNA as a nucleoprotein filament (RecA*).

105 , which stimulates ATP turnover in the Rad51 nucleoprotein filament and causes dissociation of Rad51

106 s with nucleation and extension of the RAD51 nucleoprotein filament and that the entropic penalty ass

107 tes, implicating the remodelling of the H-NS nucleoprotein filament and the subsequent restoration of

108 Here, we studied the kinetics of the nucleoprotein filament assembly of Saccharomyces cerevis

109 and highlight a regulation strategy in Dmc1 nucleoprotein filament assembly.

110 two different mechanisms, modifies the RAD51 nucleoprotein filament formation, and allows RAD51 to co

111 with straightening of single-strand DNA upon nucleoprotein filament formation.

112 process, a single-stranded DNA (ssDNA)-RecA nucleoprotein filament invades homologous dsDNA, pairing

113 RAD51 is an ATPase that forms a nucleoprotein filament on single-stranded DNA.

114 timulatory effect is not the result of RAD51 nucleoprotein filament stabilization; rather, we demonst

115 The active form of RAD51 is a nucleoprotein filament that assembles on single-stranded

116 The nucleoprotein filament then invades homologous DNA to dr

117 fully covered with a viral protein forming a nucleoprotein filament with attractive interactions betw

118 es is an ability to stabilize the Rad51/Dmc1 nucleoprotein filament, and we propose that it is this p

119 The resulting nucleoprotein filament, known as the presynaptic complex

120 s of human RAD51 and properties of the RAD51 nucleoprotein filament.

121 a strong RAD51-RAD51 interaction within the nucleoprotein filament.

122 on of RAD51 onto ssDNA to form a presynaptic nucleoprotein filament.

123 ing that a high interaction rate between the nucleoprotein filaments and the dsDNA can be achieved.

124 ScDmc1 nucleoprotein filaments are less stable than the ScRad51

125 Disruption of H-NS nucleoprotein filaments by DNA bending is a suggested me

126 The mechanism by which pre-synaptic RecA nucleoprotein filaments efficiently locate sequence homo

127 mplished by RecA proteins that are active as nucleoprotein filaments formed on single-stranded segmen

128 s been implicated in the disassembly of RecA nucleoprotein filaments in vivo and in vitro.

129 s the RAD51 recombinase, which forms helical nucleoprotein filaments on single-stranded DNA (ssDNA) a

130 During homology search, Rad51 nucleoprotein filaments probe and interact with dsDNA, f

131 Rad52 helps assemble Rad51-ssDNA nucleoprotein filaments that catalyze DNA strand exchang

132 flects a physical interaction with the RecA* nucleoprotein filaments that has been detected previousl

133 Bacterial H-NS forms nucleoprotein filaments that spread on DNA and bridge di

134 G151D forms mixed nucleoprotein filaments with WT RAD51 that have intermed

135 ion of DNA molecules and on the size of RecA nucleoprotein filaments, in agreement with experimental

136 tions alter the physical properties of RAD51 nucleoprotein filaments, with G151D showing the most dra

137 mediator complex, which stabilizes RAD51-DNA nucleoprotein filaments.

138 therwise occur during assembly of Dmc1-ssDNA nucleoprotein filaments.

139 During nucleoprotein formation HOP2-MND1 helps to load RAD51 on

140 e) but consistently negative for Ebola virus nucleoprotein gene (not in the vaccine).

141 ntly positive for vesicular stomatitis virus nucleoprotein gene and Ebola virus glycoprotein gene (bo

142 f 20-nt target sequences from the Ebolavirus nucleoprotein gene in a constant-temperature environment

143 By targeting SARS-CoV-2's nucleoprotein gene, two CRISPR RNAs without protospacer

144 (IgG), 89 (15.8%) were seroreactive for anti-nucleoprotein IgG, and 54 (9.5%) were VP40 positive.

145 wer the limit of detection of an influenza A nucleoprotein immunoassay by over 50%.

146 lated from plasma samples in which anti-EBOV nucleoprotein immunoglobulin G was detected.

147 he detection of SARS-CoV-2 spike protein and nucleoprotein in a relevant biological matrix.

148 S165) within the groove of influenza A virus nucleoprotein inhibits oligomerization and, consequently

149 Although a number nucleoprotein interactions involving PAN have been impli

150 astic network of RNA-RNA and potentially RNA-nucleoprotein interactions to coordinately incorporate i

151 Further analysis of the nucleoprotein intermediates demonstrated that the transp

152 d, the nature of the catalytically competent nucleoprotein intermediates, and the mechanism describin

153 oprotein complex, the oligomerization of the nucleoprotein is mediated by an interaction between the

154 n a sandwich immunoassay for influenza virus nucleoprotein; it used an enzyme-labeled antibody and a

155 rget autoantigens are derived from a protein/nucleoprotein mixture prepared from an inexpensive sourc

156 d nucleic-acid components to form engineered nucleoprotein motors may enable additional sophisticated

157 Our designs include nucleoprotein motors that reversibly change direction in

158 virus is wrapped around the virally encoded nucleoprotein N to form the ribonucleoprotein complex (R

159 capsid (the viral RNA genome packaged by the nucleoprotein N) we present crystallographic structures

160 ial virus (RSV) is encapsidated by the viral nucleoprotein N.

161 dered C-terminal domain of the measles virus nucleoprotein (N(TAIL)) and the X domain (XD) of the mea

162 We find that the viral nucleoprotein (N) and phosphoprotein (P) are sufficient

163 Here, we show that the hRSV nucleoprotein (N) could be at least partially responsibl

164 xpression system to produce recombinant RVFV nucleoprotein (N) for use as serodiagnostic antigen in a

165 ing to certain outbreaks on the basis of the nucleoprotein (N) gene sequence only, as the diversity o

166 similar to those of complete genome and the nucleoprotein (N) gene.

167 tly embedded within a nucleocapsid made of a nucleoprotein (N) homopolymer.

168 Nucleoprotein (N) is an immunodominant antigen in many e

169 .3 kb encapsidated by multiple copies of the nucleoprotein (N), giving rise to helical nucleocapsids.

170 tics to create chimeric VHSVs in which viral nucleoprotein (N), P (phosphoprotein), or M (matrix prot

171 form inclusion bodies, minimally composed of nucleoprotein (N), phosphoprotein (P), and viral RNA (vR

172 In a previous analysis in HEp-2 cells, the nucleoprotein (N), phosphoprotein (P), matrix protein (M

173 The viral genome, packaged by the nucleoprotein (N), serves as a template for the polymera

174 immunosorbent assays (ELISAs) targeting the nucleoprotein (N), the S1 domain of the spike protein (S

175 -RNA template and acts as a chaperone of the nucleoprotein (N), thereby preventing nonspecific encaps

176 rmined the 3D X-ray crystal structure of the nucleoprotein (N)-RNA complex from PIV5 to 3.11-A resolu

177 ARS-CoV-2 antibodies targeting spike (S) and nucleoprotein (N).

178 ), polymerase protein (L), M2-1 protein, and nucleoprotein (N).

179 d by viral RNAs that are encapsidated by the nucleoprotein (N).

180 ated rhabdovirus MPs only with their cognate nucleoproteins (N) and phosphoproteins (P).

181 either the hemagglutination (HA [H]) or the nucleoprotein (NP [P]) gene of the influenza A/PR8 virus

182 e, that the HLA-B27 immunodominant influenza nucleoprotein (NP) 383-391 epitope is made as an N-termi

183 A restriction can be achieved when the viral nucleoprotein (NP) acquires the critical human-adaptive

184 Interestingly, the expression of the viral nucleoprotein (NP) alone is sufficient for the generatio

185 expression levels of reporter genes from the nucleoprotein (NP) and glycoprotein precursor (GPC) loci

186 , we found that the combined introduction of nucleoprotein (NP) and hemagglutinin (HA) from an H5N1 v

187 nia Ankara (MVA)-vectored vaccine expressing nucleoprotein (NP) and M1 (MVA-NP+M1) to activate M1-spe

188 an increased ratio of hemagglutinin (HA) to nucleoprotein (NP) and M1 compared to values for their w

189 ersal" vaccines targeting the viral antigens nucleoprotein (NP) and matrix 2 (M2), which are conserve

190 We define all epitopes in the nucleoprotein (NP) and matrix protein (M1) with experime

191 hat efficient interaction between arenavirus nucleoprotein (NP) and RNA-dependent RNA polymerase (L p

192 P also interacts with the viral nucleoprotein (NP) and self-associates to form a homotet

193 Interestingly, virus protein 24 (VP24) and nucleoprotein (NP) appear to be major virulence factors

194 show that distinct amino acids of the viral nucleoprotein (NP) are required for packaging of specifi

195 hin the virus surface glycoprotein (GPC) and nucleoprotein (NP) are the main targets of the Lassa vir

196 Additional incorporation of Aichi nucleoprotein (NP) but not the hemagglutinin (HA), neura

197 tope within an alpha-helical assembly at the nucleoprotein (NP) C-terminus that was conserved through

198 We recently demonstrated that the viral nucleoprotein (NP) determines resistance of seasonal and

199 T-cell responses to A(H3N2) virus nucleoprotein (NP) dominated and strongly cross-reacted

200 of a ribonucleoprotein complex in which the nucleoprotein (NP) encapsidates the single-stranded RNA

201 We found that nucleoprotein (NP) enhances the phosphorylation of P.

202 Accordingly, the arenavirus nucleoprotein (NP) has been identified as a potent IFN-I

203 B1), polymerase basic 2 (PB2), and also with nucleoprotein (NP) in an RNA-dependent manner.

204 ng influenza virus hemagglutinin (HA) and/or nucleoprotein (NP) in cynomolgus macaques.

205 The influenza A virus nucleoprotein (NP) is an essential multifunctional prote

206 IAV nucleoprotein (NP) is known to mediate the nuclear impor

207 lation we demonstrate the reduction of viral nucleoprotein (NP) level and inhibition of influenza vir

208 species, including hemagglutinin (HA) A125T, nucleoprotein (NP) M105V, and NP S377N.

209 randed RNA segments that are coated by viral nucleoprotein (NP) molecules.

210 ing the glycoprotein precursor (GPC) and the nucleoprotein (NP) of CCHFV.

211 A was able to form stable complexes with the nucleoprotein (NP) of IAV.

212 ion between polymerase basic 2 (PB2) and the nucleoprotein (NP) of influenza A viruses.

213 The nucleoprotein (NP) of influenza viruses is a multifuncti

214 We recoded the nucleoprotein (NP) of the prototypic arenavirus lymphocy

215 irected toward an extended influenza-derived nucleoprotein (NP) peptide and show that only ~35% indiv

216 hemagglutinin (HA), neuraminidase (NA), and nucleoprotein (NP) proteins.

217 viruses in the presence of cycloheximide or nucleoprotein (NP) small interfering RNA (siRNA), which

218 strictors with increased binding to the THOV nucleoprotein (NP) target protein and 10-fold higher ant

219 aryopherins (KPNAs), which bind to the viral nucleoprotein (NP) via its N-terminal nuclear localizati

220 ens, wherein direct infection drives optimal nucleoprotein (NP)(366-374) presentation, while cross-pr

221 ody fragments (VHHs) against influenza virus nucleoprotein (NP), a viral protein essential for nuclea

222 RNA polymerase, glycoproteins G(n) and G(c), nucleoprotein (NP), and a nonstructural S segment (NSs)

223 s were located in the polymerase complex and nucleoprotein (NP), and all isolates carried mutations i

224 uences and specific amino acids in the viral nucleoprotein (NP), both components of each vRNP, ensure

225 ed viral proteins, primarily ISGylated viral nucleoprotein (NP), in infected cells.

226 l acetylation sites of the influenza A virus nucleoprotein (NP), including the lysine residues K77, K

227 usion bodies (IB), comprised mainly of viral nucleoprotein (NP), similar to those observed in BIBD an

228 1, migrating to the nucleus to phosphorylate nucleoprotein (NP), the major constituent of vRNPs.

229 3 expression cassette that expresses a viral nucleoprotein (NP)-specific artificial microRNA from an

230 n assay, and hemagglutinin (HA)-specific and nucleoprotein (NP)-specific CD4(+) T-cell responses were

231 Nucleoprotein (NP)-specific CD8(+) T cells encountered a

232 viral polymerase, genomic RNA and oligomeric nucleoprotein (NP).

233 lymerase subunits (PB2, PB1, and PA) and the nucleoprotein (NP).

234 ormation through interactions with the viral nucleoprotein (NP).

235 ctors (LV) coexpressing 4-1BBL and influenza nucleoprotein (NP).

236 ay for viable virus, and production of virus nucleoprotein (NP).

237 he T-to-C substitutions at the 3'-UTR of the nucleoprotein (NP; positions 3008 and 3011), observed in

238 d with Xpert (targets: glycoprotein [GP] and nucleoprotein [NP] genes) and Trombley (target: NP gene)

239 he internal proteins (matrix protein 1 [M1], nucleoprotein [NP], polymerase basic protein 1 [PB1]).

240 Vaccinia Ankara-vectored vaccine expressing nucleoprotein(NP) and M1(MVA-NP+M1) to activate M1-speci

241 al factor in Ebola virus IB formation is the nucleoprotein, NP, which also is important in RNA encaps

242 The nucleoprotein (NPs) of all arenaviruses carry a unique e

243 Arenavirus nucleoproteins (NPs) contain a highly conserved exoribon

244 e overall fold of PepMV CP resembles that of nucleoproteins (NPs) from the genus Phlebovirus (family

245 entify human proteins that interact with the nucleoproteins (NPs) of the Old World arenavirus lymphoc

246 ctural and functional analyses of arenavirus nucleoproteins (NPs) revealed a conserved DEDDH exoribon

247 etween the disordered domain of Sendai virus nucleoprotein (NT) and the C-terminal domain of the phos

248 rdered C-terminal domain of the Hendra virus nucleoprotein (NTAIL) and compared its interfacial prope

249 Insights into nucleoprotein-nucleoprotein interactions have been deriv

250 ld strengths on the C-terminal domain of the nucleoprotein of Sendai virus, over a large range of tem

251 ncreased binding of unmethylated oligos with nucleoproteins of cells maintained under HG.

252 clonal antibodies raised against recombinant nucleoproteins of representative strains from the three

253 We propose that nucleoprotein oligomerization in infected cells is regul

254 -terminal region of nucleoprotein-core links nucleoprotein oligomerization, nucleocapsid condensation

255 ParA is an ATPase that interacts with nucleoprotein ParB complexes - segrosomes and non-specif

256 Furthermore, the amount of viral nucleoprotein per focus forming unit differed markedly w

257 s, cytosolic inclusion bodies containing the nucleoprotein, phosphoprotein, and respective viral geno

258 r results show that CD8(+) T cells targeting nucleoprotein play an important role in shaping influenz

259 The structure also suggests a model of nucleoprotein-polymerase interaction that would enable r

260 for ultrasensitive detection of recombinant nucleoprotein, reaching a detection limit of 4 +/- 1 fM

261 ompounds targeting the fusion protein or the nucleoprotein) reduced viral load immediately postinfect

262 ormally subdominant, cross-reactive epitope (nucleoprotein residues 205 to 212, or NP205).

263 avirus LCMV encoding codon-deoptimized viral nucleoproteins (rLCMV/NP(CD)).

264 P positions the viral polymerase onto its nucleoprotein-RNA template and acts as a chaperone of th

265 branes composed of amphiphilic lipids, these nucleoprotein-RNA vesicular membranes exhibit local orde

266 ading to exposure and aberrant processing of nucleoprotein self antigens, and discuss their role in t

267 A substantial proportion of lung nucleoprotein-specific memory CD8(+) T cells expressed C

268 ipheral blood, a high frequency of influenza nucleoprotein-specific memory T cells was detected in th

269 ed on spatial and temporal analyses of viral nucleoprotein staining of lung tissue sections and disso

270 consequently, in generating the appropriate nucleoprotein structure for DNA synthetic reactions requ

271 PA-coated single-stranded DNA (RPA-ssDNA), a nucleoprotein structure induced by DNA damage, promotes

272 ized into chromosomes and capped by a unique nucleoprotein structure, the telomere.

273 r DNA replication, creating a recombinogenic nucleoprotein structure.

274 more comprehensive dynamic analysis of large nucleoprotein structures and their mechanisms.

275 needed to load Gp41 onto D-loops, and other nucleoprotein structures containing clusters of Gp32.

276 Chromosome ends contain nucleoprotein structures known as telomeres.

277 ding sequences in the assembly of long-range nucleoprotein structures remains unknown.

278 charomyces cerevisiae, mtDNA is organized in nucleoprotein structures termed nucleoids, which are dis

279 tion of regulatory proteins with the complex nucleoprotein structures that are found in mammalian cel

280 ngements result in various three-dimensional nucleoprotein structures that differ in their shape and

281 Telomeres, the nucleoprotein structures with repetitive (TTAGGG) sequen

282 tes and stabilization of distinct long-range nucleoprotein structures.

283 CRISPR-Cas nucleoproteins target foreign DNA via base pairing with

284 ipid nanoparticle (LNP) delivery of a single nucleoprotein-targeting (NP-targeting) siRNA in nonhuman

285 S DNA interact together to form a high-order nucleoprotein that is required for the loading of the st

286 at the novel H7N9 bird IAV already carries a nucleoprotein that overcomes the inhibition of viral rep

287 olves under pressure to fix mutations in the nucleoprotein that promote escape from T cells.

288 irely embedded into a helical homopolymer of nucleoproteins that constitutes the nucleocapsid.

289 tilizes a complex consisting of genomic RNA, nucleoprotein, the RNA-dependent RNA polymerase, and a p

290 ssociated with specific amino acids in their nucleoproteins, the target of Mx function.

291 Interactions between TARBP2 and the nucleoprotein TPR then promote degradation of these TARB

292 hly conserved E339...R416 salt bridge of the nucleoprotein trimer as a target and compound 1 as an in

293 cal and global conformational changes in the nucleoprotein upon assembly, in particular involving hel

294 subunits S1 and receptor binding domain, and nucleoprotein were coupled to microspheres.

295 Recombinant full-length spike protein and nucleoprotein were digested and proteotypic peptides wer

296 en commercial antibodies against influenza A nucleoprotein were methodically tested for their reactiv

297 10% of wild-type cells contained detectable nucleoprotein, whereas knockout of FAM134B resulted in 8

298 ICP4 is a viral nucleoprotein which binds double-stranded DNA.

299 ts are based upon detection of the influenza nucleoprotein, which are limited in that they are unable

300 neered avian H7N7 influenza virus carrying a nucleoprotein with signature mutations typically found i