ライフサイエンスコーパス: obviate

1 sk for enterococcal IE and that TEE could be obviated.

2 he current requirement for DNA sequencing is obviated.

3 risk of ciTBIs for whom CT can routinely be obviated.

4 This approach could be useful, obviating (18)F-FDG scans when longer-lived amyloid imag

5 al elevation in Ca(2+) dynamics, which would obviate a need for increased beta-AR signaling to improv

6 Taken together, these results obviate a paradox of selective insulin resistance, becau

7 fusion led to important ecological insights, obviated a commonly ignored type of collinearity, and wa

8 , SL identified 94.1% of the DLs and thereby obviated a nontherapeutic laparotomy in 55.9% of patient

9 cell-autoreactive CD8 T cells in NY8.3 mice obviated a role for CD137 in diabetogenesis.

10 This high contrast obviates a following quantum-limited amplifier.

11 It obviates a separate surgical procedure but requires long

12 r reprogramming factor (RF) expression while obviating a cleanup phase to purge residual traces of ve

13 inactivating promoter mutation, in contrast, obviates all three.

14 Obviating an external trigger for reactivity and affordi

15 The strategy used in this study would obviate any potential concerns regarding the use of MIP

16 llaborate, desensitize Hsp104 to inhibition, obviate any requirement for Hsp70, and enhance ATPase, t

17 apacity sterol transport and esterification, obviating any requirement for soluble intermediary prote

18 -care testing method for GAS pharyngitis and obviate backup testing on negative results.

19 ucturally modified superhydrophobic surfaces obviate bacterial resistance common with chemical agents

20 to arrive at an early diagnosis and also to obviate biopsy in cases with classical imaging findings.

21 This obviates both the need for a time zero spectrum as well

22 The iMAP simultaneously obviates both the O1 and O6 protection, and the differen

23 , and nonadherence; these limitations may be obviated by a sustained release formulation.

24 induction of brain death-a decline that was obviated by administration of ethyl nitrite.

25 le the overt consequences of Mcl-1 loss were obviated by combining with the loss of Bax and Bak, mito

26 induction of this tolerant state by ECP was obviated by cotreatment with lipopolysaccharide, suggest

27 n conventional sorbent-based extraction, was obviated by dissolving the sorbent in acid after extract

28 ere, we demonstrate that assumption I can be obviated by equilibrating a silicone sampler with chemic

29 ly-distinct individuals whose cooperation is obviated by evolutionary conflicts of interest.

30 Inactivation/death was obviated by the use of nonbiological colloids in column

31 rboxamide bis(diazaphospholane) ligands that obviates chromatographic purification is presented.

32 cannot be used by Pseudomonas aeruginosa to obviate coaBC.

33 hylene diamine tetraacetic acid treatment to obviate complement interference.

34 sks, to alter the natural history of DCM and obviate complications such as HF/arrhythmias.

35 Here, unadulterated samples obviate concerns about downstream purity and also exhibi

36 ic means to justify l-thyroxine monotherapy, obviating concerns about inconsistencies with desiccated

37 The data added by 3D ultrasound may obviate confirmatory testing with magnetic resonance ang

38 questions in a relevant cell model of FRDA, obviating confounding effects of variable genetic backgr

39 s are under way to determine whether PET can obviate consolidation radiotherapy in patients with diff

40 This approach obviates conventional relative quantification using an i

41 th can be used in paraffin sections, thereby obviating cumbersome oil red O staining of frozen sectio

42 the system provides multi-user support that obviates current practices of sharing data sets as files

43 We anticipate that this approach could obviate currently used needle-based vaccination methods

44 e an alternative strategy for labelling that obviates dependence on viral tropism and promoter penetr

45 placement strategy overcomes this problem by obviating direct labeling of the target DNA.

46 for the determination of As, Hg and Pb that obviate dissolution and mineralization.

47 ore ratios are measureable through the skin, obviating drawbacks of dual sugar absorption tests.

48 is, application of the NOVA score may safely obviate echocardiography in 14%-27% of patients with E-B

49 and diet-induced obesity mice, suggesting CR obviates epigenetic alterations concurrent with chronic

50 in the future, RDTR/SCF-LVs might completely obviate ex vivo handling and simplify gene therapy for m

51 the absence of rigorous temperature control, obviates extended detector equilibration wait times.

52 of patients with a clinical diagnosis of SVT obviates extensive imaging and laboratory workup and may

53 Our procedure obviates extraction into organic solvents, postreaction

54 of the consensus SUMOylation site, Lys(447), obviated Hsp27-mediated F508del NBD1 SUMOylation and deg

55 rapy represents an autologous transplant, it obviates immune suppression before and after transplant,

56 oped a simple peptide vaccine construct that obviates immunodominance, resulting in a broadly protect

57 ys that restrict their explanatory power and obviate important subtleties.

58 Protease inhibitor therapy could be obviated in genotype 1-infected treatment-naive patients

59 ncreasingly complex metal catalysts, thereby obviating in many cases the exact influence of the base,

60 libration curves for all strong acid anions, obviating individual calibrations.

61 fforded by electronically active systems and obviating issues with chronic implants.

62 ion reduces the required amount 100-fold and obviates its dependence on TLR signaling.

63 and a signal enhancement of 4 x 10(3), thus obviating key constraints in semiconductor strain metrol

64 w Vt and Elevated End-Expiratory Pressure to Obviate Lung Injury], and FACTT [Fluids and Catheter Tre

65 y environment, however electronic cigarettes obviate many of these issues, and provide a close simula

66 ver, nuclear PRMT1 was not stable postmortem obviating meaningful evaluation of ALS autopsy cases.

67 Knockdown of AMPD obviated metformin stimulation of glucose transport.

68 g process-labile TT in PLGA was found to: a) obviate micronization- and organic solvent-induced TT de

69 damage, reverse membrane depolarization, and obviate mitophagy.

70 iple be linked to virtually any surface, and obviate monitoring deformations of elastic substrates.

71 The SGS protocol obviated most molecular steps in conventional methods an

72 ivery of a synthetic tumor suppressor mimic, obviating obstacles associated with viral-based miRNA de

73 geted T cells modified to secrete IL-12 will obviate or reduce the need for potentially hazardous con

74 lar BCC or basal cell nevus syndrome and can obviate orbital exenteration in some patients.

75 obilized but releasable misfolded protein to obviate possible chaperone effects on substrate physical

76 ation of MM and if selectively inhibited may obviate progression and relapse.

77 The ability to obviate radical transport by disrupting the hydrogen bon

78 nsequent minimization of toxicity, and could obviate repeated drug administrations or device implanta

79 Coronal-load implants obviate resident bone remodeling without compromising lo

80 s and BCR-ABL may eliminate dormant LSCs and obviate resistance.

81 Such a proposal would not obviate rights under the IQA to obtain raw data at a lat

82 marrow composition and hemodynamics in vitro obviates risks associated with platelet procurement and

83 atients at low risk of cognitive impairment (obviating screening) and (2) to simplify a predictive mo

84 ated; thus, the problem of aberration can be obviated simply by selecting a chip material that matche

85 llogeneic CDCs, if safe and effective, would obviate such limitations.

86 his immunotherapy could enable physicians to obviate suppressive tumors while avoiding systemic treat

87 If supported by further research, CBVT may obviate surgical reentry as a technique for assessing re

88 edforward FGFR1-ETS2 angiocrine cascade that obviates TEC IGFBP7.

89 es how experimentally observed filopodia can obviate the classical Euler buckling condition and remai

90 enable single dose delivery, and potentially obviate the cold chain.

91 crystal structures identified strategies to obviate the DDI liability, leading to compound 16, which

92 r induced illness and their management might obviate the development of this disorder.

93 on, using horizontal saccadic latencies that obviate the impact of limb slowness on executing respons

94 on of aryl carbon-hydrogen (C-H) bonds would obviate the inefficiencies associated with generating ha

95 promising approach is the use of agents that obviate the mutation.

96 To obviate the necessity and complexity of conjugating two

97 This is sufficient to obviate the need for amplification in many cases.

98 tests, the absence of any positive test can obviate the need for antifungal agents with a negative p

99 Deformation-tracking could potentially obviate the need for bespoke strain sequences, reducing

100 latable, belatacept-based regimen that could obviate the need for both CNIs and steroids.

101 e findings show that heat inactivation could obviate the need for category 3 laboratories to perform

102 rtant immune checkpoint has the potential to obviate the need for chronic immunosuppression.

103 Tests that obviate the need for decontamination may offer an altern

104 -energy coronary CT angiographic studies may obviate the need for dedicated CT calcium scoring studie

105 EBFC)-based self-powered biochemical sensors obviate the need for external power sources thus enablin

106 a critical p53-independent function and may obviate the need for genomic alterations to the p53 path

107 As such, our results obviate the need for hidden-reservoir or super-chondriti

108 , prednisone, and rituximab (DA-EPOCH-R) may obviate the need for highly dose-intensive chemotherapy

109 g organogenesis [embryonic day 28 (E28)] can obviate the need for immune suppression in rats or rhesu

110 A 'pro re nata' (PRN) injection protocol may obviate the need for intervention.

111 patients with leptomeningeal metastasis and obviate the need for intra-CSF chemotherapy.

112 These new treatments do not obviate the need for lifestyle and dietary management, a

113 ted or decompensated cirrhosis, and delay or obviate the need for liver transplantation in some patie

114 ring treatment of ovarian cancer as it would obviate the need for more invasive surgical biopsies.

115 t extent sex-specific gametocyte diagnostics obviate the need for mosquito feeding assays to formally

116 urden, concrete, and iron and steel slag) to obviate the need for new mining, as well as uncertaintie

117 eneficial for perioperative pain and perhaps obviate the need for oral narcotics.

118 nd potential treatments for TED patients and obviate the need for reconstructive surgical therapies.

119 with a failed surgical bioprosthesis and may obviate the need for reoperation.

120 ly controllable, resorbable devices not only obviate the need for secondary surgeries and retrieval,

121 led cortical-sparing adrenalectomy which may obviate the need for steroid hormone replacement in pati

122 on (AR) in heart transplant recipients could obviate the need for surveillance endomyocardial biopsie

123 inical, physiological, and radiological data obviate the need for the increased risk associated with

124 me imaging and no ionizing radiation and may obviate the need for the patient to schedule additional

125 ith targeted therapies or immune therapy may obviate the need for WBRT; prospective studies are requi

126 pectral AP alternans during sinus rhythm may obviate the need to actually demonstrate AF, such as on

127 nhanced water heating treatment system could obviate the need to use fuels or electricity to heat wat

128 We show that eIF5A can obviate the polyamine requirement for general translatio

129 H and C1-C2 activation by UndA; these routes obviate the problematic steps of the earlier hypotheses

130 Suppressor mutations were isolated that obviate the requirement for essential PBP2b in periphera

131 on to a highly expressed endogenous gene may obviate the requirement for nucleases and/or vector-born

132 Spy1 confers structural changes to Cdk2 that obviate the requirement of Cdk activation loop phosphory

133 he foundation for genomic manipulations that obviate the requirements for double-strand breaks and ho

134 The reduction of the systemic dose may obviate the side effects.

135 se results highlight the ability of IL-12 to obviate the strict requirement for administering high le

136 he use of the most proven/viable approaches, obviate the use of ineffective measures, and avoid unwar

137 ful application of several key concepts that obviate the well-known disadvantages of SnTe.

138 phatidylinositol 3-kinase inhibitor LY294002 obviated the ability to sense substrate stiffness, sugge

139 etion of p53 at the time of tumor initiation obviated the acquisition of later deletions, establishin

140 inal assessments of the same individuals, we obviated the many sources of variation in brain structur

141 Provision of exogenous IL-2 obviated the need for conventional CD4(+) T cells in the

142 This composition obviated the need for external energy sources and allowe

143 Therapy with DA-EPOCH-R obviated the need for radiotherapy in patients with prim

144 catalytically inactive ternary complexes and obviated the need for using 2',3'-dideoxy-terminated oli

145 ined using nanomolar concentrations of BARAC obviated the need for washing steps.

146 ent transitions to holocentricity in insects obviated the need to maintain CenH3, which is otherwise

147 on of Mycobacterium tuberculosis in vivo, we obviated the requirement for antimicrobial immunity and

148 reation of a "perfect" animal model and have obviated the translation of animal findings.

149 Our approach obviates the choice of the lasso parameter by imposing a

150 s and the inherent flexibility in CGD design obviates the concern that DRAs present in the standing g

151 PCA obviates the customary focus on specific peaks or region

152 Importantly, in situ DNase Hi-C obviates the dependence on a restriction enzyme to diges

153 The stepwise mechanism obviates the electronic requirement inherent to a concer

154 This method obviates the general prerequisite for chromophoric metal

155 work as a first-pass screening device which obviates the necessity of multiple and wasteful specimen

156 -duck/egg system can be scaled as needed and obviates the necessity of using limited blood products o

157 Such a mechanism obviates the need for a decarboxylase and is consistent

158 The approach also obviates the need for a high-resolution microscope and o

159 subducted atmospheric Xe and MORB Xe, which obviates the need for a less degassed deep-mantle reserv

160 This approach obviates the need for a secondary screen to avoid cytoto

161 nduced mechanism of disulfide bond formation obviates the need for a thiol/disulfide oxidoreductase i

162 The latter characteristic obviates the need for an extra framed holder for rapid T

163 ar biosynthesis of spin-labeled proteins and obviates the need for any chemical labeling step usually

164 The method obviates the need for any high frequency RF components a

165 Likewise, this unified approach obviates the need for both electron spin resonance manip

166 erently high cross-selectivity of the system obviates the need for directing groups or a large excess

167 This process obviates the need for exogenous enzymes and redox mediat

168 rom human plasma and tissue derived RNA, and obviates the need for gel-separation, greatly increasing

169 h the CO and an active catalyst, and thereby obviates the need for handling a toxic gas.

170 The use of the tailed primers obviates the need for hapten labelling and consequent us

171 tilage development, but also its elimination obviates the need for Hif1alpha to promote chondrocyte s

172 d (ii) a one-step (18)F-labeling method that obviates the need for HPLC purification.

173 Optimal clustering with missing values obviates the need for imputation-based pre-processing of

174 VAMPS obviates the need for individual research groups to make

175 stick monitoring, a higher HbA1c target that obviates the need for insulin may be appropriate.

176 tteries because, unlike elemental sulfur, it obviates the need for metallic lithium anodes.

177 riability to assign reads to isolates, which obviates the need for molecular barcoding.

178 Here we present a sensor design that obviates the need for optical addressability by operatin

179 sation steps proceeds under mild conditions, obviates the need for oxidants, releases N2 and H2O as t

180 ty and consumer-resource oscillations, which obviates the need for parameterizing complex dynamical m

181 The method we employ obviates the need for permanent implants and could poten

182 and STORM for studies of Ca2+ channels as it obviates the need for photoswitchable labels and provide

183 thod for analyzing heterogeneous populations obviates the need for pre- or post-enrichment and simpli

184 tion, and the absence of host immunity often obviates the need for preconditioning.

185 es via an operationally simple protocol that obviates the need for prefunctionalization or preactivat

186 ly a single sample is required, the approach obviates the need for preparing multiple samples and eli

187 le, low-dispersion electrophoretic transport obviates the need for pumps and valves.

188 The impact of ethnicity is minimal, which obviates the need for race-specific RV reference values.

189 strategy that improves the rate of cure and obviates the need for radiotherapy.

190 amplification of desired sequences and that obviates the need for solid-phase capture, washing, and

191 ions with aryl bromides as coupling partners obviates the need for stoichiometric organometallic reag

192 The CS linkage probably obviates the need for strong interactions between b(5) a

193 This process obviates the need for the harsh deprotection conditions

194 This method obviates the need for the high-dilution conditions usual

195 otein, not merely highly conserved ones, and obviates the need for the time consuming, expensive, and

196 Our approach obviates the need for transcript annotations and circumv

197 topic stimulation of this signalling cascade obviates the need for tuft cells in the epithelial cell

198 ell is potentially more efficient because it obviates the need for two separate cell lines and purifi

199 ability of these simple complementary assays obviates the need for undesirable radiotracer-based assa

200 finding is that the presence of acetonitrile obviates the need for using excess amounts of a more val

201 kylation or alkenylation reactions, and thus obviates the need to access 1,4-dicarbonyl compounds via

202 uctor (SS-OPV) offers several advantages: it obviates the need to control the highly system-dependent

203 blishes the chirality of the tertiary azide, obviates the need to directly forge either a congested C

204 f a photolabile group on the amine precursor obviates the need to employ a photoredox catalyst in thi

205 nomical strategy used by the cell because it obviates the need to further deplete cellular iron level

206 effect helps overcome these limitations and obviates the need to make hard x-ray absorption gratings

207 res, 4- and 6-azaindoles and thienopyrroles, obviates the need to prepare potentially toxic aryl hydr

208 This strategy obviates the need to regulate multiple genes and decreas

209 how PG synthesis might drive engulfment, and obviates the need to synthesize a PG layer de novo durin

210 This convenient method obviates the need to use highly reactive agents for chem

211 This protocol obviates the purification techniques such as column chro

212 tation of either the c-Src SH2 or SH3 domain obviates the RANK/alphavbeta3 association.

213 ditions of stress by resisting apoptosis and obviates the requirement for serum or a feeder layer for

214 repare N(2)-acyl analogues in a fashion that obviates the troublesome acylation of the free 2-aminoim

215 Isothermal amplification, on the other hand, obviates the use of a thermal cycler because reactions o

216 linked enzyme coatings on intact CNTs, while obviating the chemical pretreatment that can seriously d

217 Merely obviating the condition of solution averaging wholly cha

218 used for detection of cell surface antigens obviating the laborious steps of protein purification an

219 etalation occurs with arylboronic acid, thus obviating the necessity of any exogenous photosensitizer

220 ost factor using small interfering RNA, thus obviating the need for a complementing cell line.

221 eered dissipation to counteract decoherence, obviating the need for a complicated external feedback l

222 l cell and simplifies electrode placement by obviating the need for a counter electrode.

223 be rescued by exogenous polyamines, thereby obviating the need for a PTI.

224 ate transient site for sulfur transfer, thus obviating the need for a rhodanese domain.

225 nor T-cell-replete bone marrow allografting, obviating the need for additional prophylactic immunosup

226 alized patients with a label of PenA thereby obviating the need for allergy tests.

227 anges the turnover limiting transition step, obviating the need for an added cocatalyst.

228 consequently decreasing the risk of SCD and obviating the need for an ICD.

229 l pandemic influenza virus strains therefore obviating the need for annual vaccination, and enhancing

230 d for both the cystic duct and artery, thus, obviating the need for any transabdominally placed instr

231 in signals are large (1-20% above baseline), obviating the need for averaging.

232 and aliphatic (18)F-fluorination reactions, obviating the need for azeotropic drying.

233 tracellular loops to some degree, apparently obviating the need for Ca(2+).

234 the success of persistent AF ablation while obviating the need for chronic anticoagulation.

235 em for its sustained local delivery in vivo, obviating the need for chronically implanted catheters a

236 a correctly assembled product in vivo, often obviating the need for clonal isolation.

237 We dramatically accelerate t-SNE, obviating the need for data downsampling, and hence allo

238 rom a graphite electrode is described herein obviating the need for defect inducing oxidative or prol

239 tion framework that uses the raw time series obviating the need for discriminant statistic while acco

240 ssemble genes across distantly-related taxa, obviating the need for draft genome assembly of all taxa

241 ectively limits the elongation rate, thereby obviating the need for evolutionary optimization of FH1

242 ng sinus rhythm and guide targeted ablation, obviating the need for extensive radiofrequency delivery

243 ephalosporin with a short half-life, thereby obviating the need for increasingly challenging SAP timi

244 application through the intact human skull, obviating the need for invasive and risky surgical proce

245 actic-co-glycolic acid) (PLGA) microspheres, obviating the need for invasive intrathecal pumps or cat

246 stic modality for congenital heart diseases, obviating the need for invasive modalities.

247 on of highly contiguous physical genome maps obviating the need for labor-intensive physical genome m

248 and production of a useful chemical oxidant, obviating the need for long-term storage.

249 alleling the extant metabolic mechanisms and obviating the need for metal-catalysed abiotic reductive

250 fractionated lysates (72 hr analysis) while obviating the need for peptide detection prior to quanti

251 onsible for object recognition, in this case obviating the need for PPC contributions and expanding P

252 ever, most patients had improvement in LVEF, obviating the need for primary prevention implantable ca

253 apted to a capillary electrophoresis format, obviating the need for radiolabeled probes and allowing

254 ntly remove water from the reaction mixture, obviating the need for rigorously dry solvents.

255 tocol is characterized by a wide scope while obviating the need for sensitive organometallic species

256 table ammonia surrogate (alpha-amino acids), obviating the need for special experimental setup or han

257 emperature, and ionic strength used, thereby obviating the need for spectral calibration with interna

258 educing concerns about reagent stability and obviating the need for storage of solutions of the highl

259 ariables as predictors of TOC concentration, obviating the need for streamflow.

260 or the treatment of large colorectal polyps, obviating the need for surgery in most instances.

261 ic stabilization from global delocalization, obviating the need for the concept of superaromaticity.

262 bility can be incorporated into the analysis obviating the need for the ubiquitous assumption that th

263 used to efficiently count transcripts while obviating the need for transcript-length normalization a

264 tical to parameters derived from blood, thus obviating the need for venous sampling in these patients

265 ures all genes are derepressed at once, thus obviating the need for VP16 to initiate sequential derep

266 compared with conventional 2-tiered testing, obviating the need for Western blots.

267 ectron temperatures in other nanostructures, obviating the need to adapt traditional, large demagneti

268 eralize the concept of adversarial examples, obviating the need to assume a ground-truth model.

269 rect access to a large minefield area, while obviating the need to endanger personnel and equipment.

270 d from the perspective of inclusive fitness, obviating the need to evoke group selection as a contrib

271 as a diffuse interface on this mesh, thereby obviating the need to explicitly track the (potentially

272 much more rapid analysis of gene function by obviating the need to initially establish stably transfo

273 the alkyl halide is generated in situ, thus obviating the need to isolate either an alkyl electrophi

274 eates the well-known crossover paradox, thus obviating the need to posit common causes of early birth

275 livering the data in a simple parsed format, obviating the need to post-process the alignment results

276 alcohol is oxidized in situ to an aldehyde, obviating the need to prepare sensitive keto aldehyde su

277 ill persisters by altering their metabolism, obviating the need to target active processes.

278 d mRNA, allows rapid screens (<4 h), thereby obviating the potential toxicity of splicing inhibitors.

279 and contains no meat or dairy products, thus obviating the problem of possible prion diseases.

280 chromatography-stable and directly isolable, obviating the requirement for an extra synthetic transfo

281 ected with different HIV-1 subtypes, thereby obviating the requirement for HIV-specific immunity.

282 he RME1 promoter reduces RME1 transcription, obviating the requirement for methylation.

283 tients with OUD, with the further benefit of obviating the risk for misuse and diversion of daily bup

284 n system, while, under the consideration for obviating the risk of mutagenic insertion and enables mo

285 d differentiation to multiple lineages while obviating the stringent needs for complex, exogenous mat

286 HC borane serves as the hydrogen donor, thus obviating the use of tin-based reagents.

287 Two-dimensional materials such as graphene obviate these issues and offer a new paradigm for tunnel

288 To obviate these limitations, we have developed an open-sou

289 id, and inexpensive to use in the office may obviate these problems.

290 e a unique strategy for dimer formation that obviates these difficulties, one which rapidly construct

291 to phenylalanine to prevent phosphorylation obviates these effects.

292 dern computed tomography (CT) technology may obviate this and allow for immediate clearance.

293 To obviate this problem, in this study we generated a human

294 To obviate this problem, silica nanoshells were tested for

295 To obviate this problem, we report here the use of a sensit

296 cellular degradation pathways is relevant to obviate toxic mHtt species and subsequent neurodegenerat

297 ural thickness and shrinking lung, and might obviate unnecessary invasive procedures for MPM.

298 factors that predict disease progression may obviate unnecessary morbidity associated with regional t

299 tiparametric MR imaging may have potentially obviated unnecessary breast biopsies in six of eight les

300 cellular carcinoma (HCC) patients, to try to obviate upfront liver transplantation, with the "safety