ライフサイエンスコーパス: odontoblast

1 associated with pre-secretory ameloblast and odontoblast.

2 did not induce premature differentiation of odontoblasts.

3 ontoblasts in comparison with WT and Dspp-Tg odontoblasts.

4 e number of DMP1-GFP(+) and DSPP-Cerulean(+) odontoblasts.

5 ranscriptional regulation of TRP channels in odontoblasts.

6 hymal stem cells that produce pulp cells and odontoblasts.

7 d TRPM8 that has previously been reported in odontoblasts.

8 functions in the kidney as compared with the odontoblasts.

9 genic and Bmp2-dependent VegfA production in odontoblasts.

10 removal of the Bmp2 gene in early-polarizing odontoblasts.

11 upted and erupted incisors that give rise to odontoblasts.

12 ntoblast polarization and reduced numbers of odontoblasts.

13 cells capable of generating ameloblasts and odontoblasts.

14 bserved in secretory stage ameloblasts or in odontoblasts.

15 , whereas Osx expression was clearly seen in odontoblasts.

16 ly undescribed novel gene synthesized by the odontoblasts.

17 g tooth enamel and reported to be present in odontoblasts.

18 hic chondrocytes, and ameloblasts as well as odontoblasts.

19 cell-specific expression of the DSPP gene in odontoblasts.

20 differentially regulated in osteoblasts and odontoblasts.

21 or the transcriptional regulation of DSPP in odontoblasts.

22 DNA binding site using nuclear extracts from odontoblasts.

23 ypes including neural cells, adipocytes, and odontoblasts.

24 e-related, inter-dependent, and regulated by odontoblasts.

25 l retrieval of total RNA from microdissected odontoblasts.

26 responsible for the formation of functional odontoblasts.

27 at a lower level in bone than in dentin and odontoblasts.

28 xpress active TGF-beta1 predominantly in the odontoblasts.

29 ion of this gene is tightly regulated in the odontoblasts.

30 ected TIP39 RNA in secretory ameloblasts and odontoblasts.

31 pressed in the center of pulp niches but not odontoblasts.

32 scription was mediated by Dlx3 and/or Osx in odontoblasts.

33 prevented their differentiation into mature odontoblasts.

34 te to tooth formation and differentiate into odontoblasts.

35 g osteocytes, hypertrophic chondrocytes, and odontoblasts.

36 DSP is mainly expressed in odontoblasts.

37 exposure, ephrinB1 was strongly expressed in odontoblasts 4 wk postinjury.

38 oth structures formed that contained dentin, odontoblasts, a well-defined pulp chamber, putative Hert

39 These studies suggest that odontoblasts actively synthesize and secrete amelogenin

40 n 1 (DMP1) and dentin sialophosphoprotein in odontoblasts, along with a sharply reduced expression of

41 sor, but the rescued teeth exhibit a delayed odontoblast and ameloblast differentiation.

42 identify a further late function of Msx1 in odontoblast and dental pulp survival.

43 rocessed fragments in extracts from the pulp/odontoblast and dentin.

44 sion identifies cells at different stages of odontoblast and osteoblast differentiation.

45 xpress marker genes of tooth-specific cells, odontoblasts and ameloblasts.

46 ecific markers for terminally differentiated odontoblasts and are encoded by a single gene DSPP (dent

47 t are expressed by terminally differentiated odontoblasts and are responsible for the formation of ti

48 Col2.3-GFP(+) cells composed of both Dspp(+) odontoblasts and Bsp(+) osteoblasts.

49 restingly, despite its lack of expression in odontoblasts and dental pulp during tooth development, t

50 ovide evidence that continuous generation of odontoblasts and dentin on the labial and lingual sides

51 arding the expression and function of BSP by odontoblasts and dentin.

52 otein (DSPP) is a major secretory product of odontoblasts and is critical for proper dentin formation

53 otein (DSPP) is a major secretory product of odontoblasts and is critical for proper tooth dentin for

54 sis showed high expression levels of DMP4 in odontoblasts and low levels in osteoblasts and ameloblas

55 EphrinB1 was continuously expressed in odontoblasts and odontoblastic processes until the compl

56 tion to obtain homogenous populations of pre-odontoblasts and odontoblasts from tissue sections of mo

57 Odontoblasts and osteoblasts develop from multipotent cr

58 that DMP1 is essential in the maturation of odontoblasts and osteoblasts, as well as in mineralizati

59 formation as these cells differentiate into odontoblasts and osteoblasts, respectively.

60 efects in RUNX2-dependent differentiation of odontoblasts and osteoblasts; RUNX2-S319-P was reduced i

61 Results showed that odontoblasts and osteocytes were specifically targeted,

62 ls for expression/deletion of other genes in odontoblasts and osteocytes.

63 n (Dspp) is mainly expressed in teeth by the odontoblasts and preameloblasts.

64 olling Bmp4 expression in mesenchyme-derived odontoblasts and pulp cells existed in other regions of

65 were injected either at the interface of the odontoblasts and the dentin or into the pulp core of man

66 apilla mesenchyme of developing teeth and in odontoblasts and the periodontal ligament (PDL) of adult

67 ated immunoreactivity of pannexin 1 and 2 in odontoblasts and their processes extending into the dent

68 y that these cells can be a single source of odontoblasts and vascular networks in dental tissue engi

69 liferating dental epithelium, differentiated odontoblast, and also hair follicle matrix epithelium.

70 contribute to the formation of pulp cells or odontoblasts, and at ratios of 1:1, they inhibit tooth f

71 ed FAM20A in secretory-stage ameloblasts, in odontoblasts, and in the eruption pathway.

72 TBC1D19 colocalized with DLX3 expression in odontoblasts, and MT-DLX3 significantly reduced expressi

73 dental papilla specific cell types, such as odontoblasts, and produce dentin, if placed in contact w

74 ncrease of immature odontoblasts, few mature odontoblasts, and sharply reduced dentinal tubules; and

75 s 8/9-encoded proteins in ameloblasts, young odontoblasts, and stratum intermedium cells.

76 rated a mouse in which Tgfbr2 was deleted in odontoblast- and bone-producing mesenchyme.

77 Together, our studies demonstrate odontoblast- and PDL-specific expression of Ddr2 in matu

78 t odontoblast cytodifferentiation leading to odontoblast apoptosis, and aberrations of dentin tubule

79 TUNEL assays indicated enhanced odontoblast apoptosis.

80 eth, such as mouse and human molars, primary odontoblasts are long-lived post-mitotic cells that secr

81 Odontoblasts are nonneuronal cells that possess many of

82 gical functions of this growth factor in the odontoblasts are not clearly understood.

83 In severe injury, necrotic odontoblasts are replaced by other pulp cells, which are

84 cascade of gene expression in the exogenous odontoblasts as the dentin formed de novo.

85 both the differentiation and maintenance of odontoblasts as well as in dentin formation.

86 exhibit the potential to differentiate into odontoblasts as well as neurons.

87 ing quality RNA from discrete populations of odontoblasts at different stages of dentinogenesis.

88 lty of targeting the papilla and presumptive odontoblasts at early stages of tooth development.

89 d EphB2 were expressed in preodontoblast and odontoblasts at postnatal day 4.

90 ovides a novel tool for the investigation of odontoblast biology.

91 and nuclear translocation of Dlx3 and Osx in odontoblasts both in vitro and in vivo.

92 erentially bound dental mesenchyme cells and odontoblasts but not dental epithelial cells or nondenta

93 progenitors in pulp cultures into functional odontoblasts but prevented their differentiation into ma

94 PV1, and TRPV4 but not TRPM8 was detected in odontoblasts by reverse transcription polymerase chain r

95 em cells (hDPSCs) and an immortalized murine odontoblast cell line (MDPC-23), to catalyze the formati

96 Thus, a transformed odontoblast cell line was created with high proliferativ

97 Therefore, generation of an odontoblast cell line would be a valuable reproducible t

98 In this study an immortalized odontoblast cell line, which has the required biochemica

99 otein 1 (DMP1) is expressed in both pulp and odontoblast cells and deletion of the Dmp1 gene leads to

100 naling pathways from the mesenchymal derived odontoblast cells and the epithelially derived ameloblas

101 1 transgene was highly expressed in pulp and odontoblast cells during post-natal developmental stages

102 soforms were expressed in preodontoblast and odontoblast cells, and in situ hybridization assay showe

103 ialophosphoprotein is expressed primarily by odontoblast cells, but is also transiently expressed by

104 ctivation of inflammatory pathways while the odontoblast cluster showed greater disturbances in trans

105 licular type while 6/7 of the samples in the odontoblast cluster were of the plexiform type (p < 0.05

106 The pulp-odontoblast complex and dentin were extracted, chromatog

107 However, a mechanism by which odontoblasts could modulate neuronal activity has not be

108 e data indicate that MT-DLX3 acts to disrupt odontoblast cytodifferentiation leading to odontoblast a

109 decreased dentin was accompanied by altered odontoblast cytology that included disruption of odontob

110 preameloblasts and continuously expressed in odontoblasts demonstrating that this -5 kb rat promoter-

111 Phex mRNA was expressed by odontoblasts (dentin), osteocytes (bone), and cementocyt

112 mal stem cells giving rise to pulp cells and odontoblasts derive from neural crest cells after their

113 , which were likely caused by disruptions in odontoblast differentiation and dentin formation.

114 Ablation of Smad4 results in defects in odontoblast differentiation and dentin formation.

115 ficult to establish whether Osx functions in odontoblast differentiation and dentin formation.

116 neural crest results in major impairment of odontoblast differentiation and dentin production.

117 Studies of odontoblast differentiation and function have been limit

118 sed, whereas Runx2 was down-regulated during odontoblast differentiation and maturation.

119 xposure of pulp cells to FGF2 alone promotes odontoblast differentiation and provides critical insigh

120 studying the modulatory effects involved in odontoblast differentiation as well as the molecular eve

121 that BMP signaling not only is important for odontoblast differentiation but also plays a crucial rol

122 Odontoblast differentiation is a complex and multistep p

123 tin sialophosphoprotein (DSPP), an important odontoblast differentiation marker, is necessary for too

124 that Decorin and Col1a1, the key markers for odontoblast differentiation that are downregulated in Wl

125 age-specific activation of transgenes during odontoblast differentiation to FGF2.

126 that BMP2 mediates DSPP gene expression and odontoblast differentiation via NF-Y signaling during to

127 n and reduced Dspp expression indicated that odontoblast differentiation was disrupted in the mutant

128 rated that the inhibitory effects of FGF2 on odontoblast differentiation were mediated through activa

129 owed that the stimulatory effects of FGF2 on odontoblast differentiation were mediated through FGFR/M

130 data suggest that DMP1 is a key regulator of odontoblast differentiation, formation of the dentin tub

131 is required for root formation by regulating odontoblast differentiation, maturation, and root elonga

132 ever, was apparently delayed, due to delayed odontoblast differentiation, mediated by a limited numbe

133 n of a BSP-GFPtpz reporter mouse line during odontoblast differentiation, reparative dentinogenesis,

134 that Twist-1 plays a key role in restraining odontoblast differentiation, thus maintaining homeostasi

135 ous exposure of pulp cells to FGF2 inhibited odontoblast differentiation, whereas early and limited e

136 nx2 and Osx are necessary for osteoblast and odontoblast differentiation, while Dspp is important for

137 egulating the stimulatory effects of FGF2 on odontoblast differentiation.

138 differentiation, while Dspp is important for odontoblast differentiation.

139 2 regulates DSPP gene transcription and thus odontoblast differentiation.

140 gulation of genes that control osteoblast or odontoblast differentiation.

141 by Shh-Cre leads to defective ameloblast and odontoblast differentiation.

142 aling is required for cell proliferation and odontoblast differentiation.

143 ells to FGF2 resulted in marked increases in odontoblast differentiation.

144 , respectively, during the advanced stage of odontoblast differentiation.

145 emonstrate that Klf5 plays a pivotal role in odontoblast differentiation.

146 nflicting results regarding their effects on odontoblast differentiation.

147 age-specific activation of transgenes during odontoblast differentiation.

148 regulating the inhibitory effects of FGF2 on odontoblast differentiation.

149 conflicting results regarding its effects on odontoblast differentiation.

150 sue-specific promoter activity and prompting odontoblast differentiation.

151 ption factors Dlx3 and Osx are essential for odontoblasts differentiation.

152 The expression of Klf5, odontoblast-differentiation markers, Dspp and Dmp1 was c

153 trix protein-1 (DMP-1) gene is identified in odontoblasts during both embryonic and postnatal develop

154 opulation also makes a small contribution to odontoblasts during primary dentinogenesis.

155 o(+) cells to a small number of newly formed odontoblasts during primary dentinogenesis.

156 ble of giving rise to a second generation of odontoblasts during reparative dentinogenesis.

157 ne the contribution of perivascular cells to odontoblasts during the development, growth, and repair

158 n response to hypoxic challenge neurosensory odontoblasts express hypoxia-inducible factor-1alpha and

159 Odontoblasts expressed the gap junction protein, connexi

160 asts synthesizing enamel matrix proteins and odontoblasts expressed the gene.

161 d their rapid transition into differentiated odontoblasts expressing DMP1-Cherry and DSPP-Cerulean tr

162 Odontoblasts extending their cellular processes into the

163 ulp pericytes are already precommitted to an odontoblast fate based on enrichment analysis indicating

164 ent third molar; (4) an increase of immature odontoblasts, few mature odontoblasts, and sharply reduc

165 xpression is required in both early and late odontoblasts for normal odontogenesis to proceed.

166 mogenous populations of pre-odontoblasts and odontoblasts from tissue sections of mouse molar cusp ti

167 Additionally, odontoblast function and pulp vitality are sustained whe

168 netic protein 2 (BMP2) plays a vital role in odontoblast function via diverse signal transduction sys

169 Odontoblasts have been suggested to contribute to therma

170 The DSP domain regulates DSPP expression and odontoblast homeostasis via a positive feedback loop.

171 have shown that high Trps1 levels in mature odontoblasts impair their function in vitro and in vivo.

172 entify the formation of tooth pulp cells and odontoblasts in bioengineered teeth.

173 rase chain reaction analyses showed that the odontoblasts in both Dspp(P19L/+) and Dspp(P19L/P19L) mi

174 are detected in both Trps1-Tg and double-Tg odontoblasts in comparison with WT and Dspp-Tg odontobla

175 Odontoblasts in dentin and osteocytes in bone contain de

176 14 mRNA was expressed by preodontoblasts and odontoblasts in developing teeth.

177 well-characterized, cells giving rise to the odontoblasts in incisors have not been fully characteriz

178 Reactionary dentin is secreted by surviving odontoblasts in response to moderate stimuli, leading to

179 in osteoblasts in virtually all bones and in odontoblasts in teeth of both embryos and postnatal mice

180 acellular matrix protein highly expressed by odontoblasts in teeth.

181 apoptotic marker caspase-3 were increased in odontoblasts in TG mice as well as in odontoblastic-like

182 The odontoblasts in the Bmp2-cKO(od) do not mature properly

183 rming odontoblasts than in the floor-forming odontoblasts in the wild-type mice and mutant mice.

184 entin, a major tooth component, is formed by odontoblasts; in contrast, bone is produced by osteoblas

185 deposition of dentin sialophosphoprotein by odontoblasts into the adjacent MDP hydrogel, indicating

186 rotein (Dspp) as a differentiation marker of odontoblasts is regulated by BMP-2.

187 the nucleus during early differentiation of odontoblasts, is able to bind specifically with the DSPP

188 preodontoblasts, while in mature, secretory odontoblasts, it is expressed at low levels.

189 In the odontoblasts, its primary function is in the extracellul

190 dentin matrix, is strongly down-regulated in odontoblasts lacking Dlx3.

191 showed only moderate disorganization of the odontoblast layer at 24 hours that completely re-organiz

192 Additionally, the odontoblast layer is structurally preserved in appositio

193 d functional ecto-ATPase activity within the odontoblast layer, subodontoblast layer, dental pulp ner

194 bundles, Raschkow's nerve plexus, and in the odontoblast layer.

195 was localized close to connexin43 within the odontoblast layer.

196 ing the nerve fibers and projecting into the odontoblast layer.

197 The cells demonstrated odontoblast-like appearances with elongated bodies and l

198 systems on growth factor solubilization and odontoblast-like cell differentiation of human dental pu

199 Overexpression of Nma/BAMBI in the mouse odontoblast-like cell line MD10-A2 down-regulated expres

200 to the dental pulp cells and restored their odontoblast-like cell phenotype to a biologically signif

201 Dental pulp cells and mouse odontoblast-like cells (MDPC-23) (+/-) treated with G5-F

202 Odontoblast-like cells (MDPC-23) and undifferentiated pu

203 gulates expression of VEGF, we exposed mouse odontoblast-like cells (MDPC-23), undifferentiated pulp

204 Mouse odontoblast-like cells (MDPC-23), undifferentiated pulp

205 spreading and proliferation of encapsulated odontoblast-like cells (OD21), and the formation of endo

206 d functional TRP channel expression in human odontoblast-like cells and measured ATP release in respo

207 cells, which are able to differentiate into odontoblast-like cells and produce a reparative dentin.

208 ogenesis and processed into fragments in the odontoblast-like cells and the tooth compartments.

209 New odontoblast-like cells are only produced in response to

210 Cell lines that differentiate into odontoblast-like cells are useful tools for studying the

211 ivation of TRPA1 and TRPV4 channels in human odontoblast-like cells can stimulate ATP release.

212 ntiation into a new generation of functional odontoblast-like cells constitutes an important step of

213 and calcium microfluorimetry, we showed that odontoblast-like cells express TRPA1 and TRPV4 and that

214 cells to proliferate and differentiate into odontoblast-like cells in response to dentine damage.

215 ghout the scaffold with differentiation into odontoblast-like cells near the dentinal walls.

216 ression of human mitochondria, and contained odontoblast-like cells organized along the dentin, as as

217 zed by the expression of CD31, and contained odontoblast-like cells organized along the length of the

218 xin2-expressing cells differentiate into new odontoblast-like cells that secrete reparative dentine.

219 Short treatment of odontoblast-like cells with tumor necrosis factor (TNF)-

220 In mouse odontoblast-like cells, Osx overexpression increased Dsp

221 tes Nma/BAMBI's expression levels in MD10-A2 odontoblast-like cells.

222 mesenchymal precursor cells into functional odontoblast-like cells.

223 e cells to differentiate and form functional odontoblast-like cells.

224 In this study, the regulation of odontoblast-like differentiation of DPSCs by canonical W

225 nical Wnt signaling negatively regulates the odontoblast-like differentiation of DPSCs.

226 showed that the effects of FGF2 on cells in odontoblast lineage were stage-specific and depended on

227 essing the alphaSMA-CreERT2 transgene to the odontoblast lineage.

228 and Osx in the regulation of osteoblast and odontoblast lineages may be independent of one another.

229 5 represses the expression of early and late odontoblast marker genes and stage-specific proteases in

230 ization as follows: 1) Trps1 is required for odontoblast maturation by supporting expression of genes

231 NA 665 (miR-665) as a potential repressor of odontoblast maturation.

232 entiation and cell fate, oral epithelial and odontoblast mesenchymal cells were reprogrammed by a two

233 ession in mouse preodontoblast (MD10-F2) and odontoblast (MO6-G3) cells.

234 In undifferentiated odontoblasts, Nrf1 and C/EBPbeta repress DSPP promoter a

235 otch expression in the dental pulp cells and odontoblasts of DSPP-null mice when compared with wild-t

236 atrix, they were remarkably increased in the odontoblasts of the Dspp(P19L/+) and Dspp(P19L/P19L) mic

237 cellular retention of the mutant DSPP in the odontoblasts of the DSPP-mutant mice.

238 neural crest cells do, in fact, give rise to odontoblasts of trunk dermal denticles.

239 ls give rise to the dentine-producing cells (odontoblasts) of teeth.

240 cribe an indirect effect of the Bmp2 gene in odontoblasts on formation of the vascular bed and associ

241 d at high levels in cementoblasts but not in odontoblasts or dentin.

242 nd PDL inhibited differentiation of cells to odontoblasts or osteoblasts, respectively.

243 Altered odontoblast organization and reduced Dspp expression ind

244 emble mature mesenchymal phenotypes, such as odontoblasts, osteoblasts, adipocytes, and myoblasts.

245 of a variety of mesenchymal cells, including odontoblasts, osteoblasts, and cementoblasts.

246 ouble-Tg) mice in which Dspp was restored in odontoblasts overexpressing Trps1.

247 ized dental pulp cells were driven toward an odontoblast phenotype by culture in conditioned media.

248 xpression for progressive development of the odontoblast phenotype.

249 enoviral expression system failed to express odontoblast-phenotypic specific genes.

250 defects in the maturation of ameloblasts and odontoblasts point to an important and non-redundant rol

251 may contribute to the observed disruption of odontoblast polarity and apoptosis.

252 toblast cytology that included disruption of odontoblast polarization and reduced numbers of odontobl

253 d eruption rates, decreased proliferation of odontoblast precursors, and increased cell apoptosis in

254 s localized in the dentin, presumably in the odontoblast processes.

255 mechanisms that maintain the equilibrium of odontoblast progenitor cells in dental pulp are unknown.

256 hen isolated from the developing tooth germ, odontoblasts quickly lose their potential to maintain th

257 olds are intercalated between dentin and the odontoblast region, a finding that has significant impli

258 critical and context-dependent functions in odontoblast-regulated mineralization as follows: 1) Trps

259 nd so the embryonic origin of trunk denticle odontoblasts remains unresolved.

260 Functional differentiation of odontoblasts requires unique sets of genes being turned

261 s 0 and 3, gene expression in laser-captured odontoblasts resembled that seen in vivo by in situ hybr

262 l-secreting ameloblasts and dentin-secreting odontoblasts, respectively.

263 etermine the role of TGF-beta1 in modulating odontoblast responses to oral bacteria.

264 ited TLR2 and TLR4 expression and attenuated odontoblast responses.

265 ffect of inflammation on the activity of the odontoblast's mechanosensitive channels remains unknown.

266 periphery of MDP scaffolds injected into the odontoblast space.

267 MDP scaffolds injected into the pulp core or odontoblast space.

268 Odontoblast-specific expression of TGF-beta1 in the toot

269 ndicated that for dental pulp pericytes, the odontoblast-specific gene Dspp was found in a transcript

270 Odontoblast-specific gene expression was studied by RT-P

271 ctor) was not required for the expression of odontoblast-specific genes, indicating the involvement o

272 Tooth injury in mice with odontoblast-specific IGF-1 receptor ablation exhibited a

273 quickly lose their potential to maintain the odontoblast-specific phenotype.

274 tpz was still exclusive to DSPP-Cerulean, an odontoblast-specific reporter gene.

275 cating the involvement of other unidentified odontoblast-specific transcription factors or coactivato

276 To identify genes that are odontoblast-specific, a subtractive hybridization techni

277 Osteoblasts and odontoblasts synthesize a polymeric collagenous matrix,

278 ains 2 additional exons; (2) ameloblasts and odontoblasts synthesize amelogenin 8/9; and (3) amelogen

279 In dentin, the odontoblasts synthesize several biomolecules that functi

280 ression were much higher in the roof-forming odontoblasts than in the floor-forming odontoblasts in t

281 expressed by chondrocytes, osteoblasts, and odontoblasts that functions in skeletal and dentin miner

282 s through the activity of specialized cells, odontoblasts, that are thought to be maintained by an as

283 In fully differentiated odontoblasts, the loss of interaction between Nrf1 and C

284 stribution of MMP9 and DSP overlapped in the odontoblasts, the predentin, and the mineralized dentin,

285 Terminal differentiation of odontoblasts, the principal cells in dentin formation, p

286 During cytodifferentiation of odontoblasts there is a constant change of actively tran

287 ing early development and differentiation of odontoblasts throughout later odontogenesis.

288 lls, fibroblasts to smooth muscle cells, and odontoblasts to adipocytes.

289 n the dentine that are believed to stimulate odontoblasts to secrete new "tertiary" dentine (reaction

290 Re-expression of Dmp1 in early and late odontoblasts under control of the Col1a1 promoter rescue

291 Damage to odontoblasts under injured dentin caused increased influ

292 In contrast, re-expression of Dmp1 in mature odontoblasts, using the Dspp promoter, produced only a p

293 the lineage progression of progenitors into odontoblasts versus osteoblasts.

294 -protein interaction between Dlx3 and Osx in odontoblasts was detected by co-immunoprecipitation.

295 at the total RNA from three-day-old captured odontoblasts was sufficient in quantity and quality.

296 on differentiation of progenitor cells into odontoblasts were stage specific and dependent on the st

297 nsdifferentiation capacities into functional odontoblasts when transplanted into the root canal micro

298 weakly present in osteoblasts, but strong in odontoblasts where Osx was highly expressed.

299 acellular tubules, and then concentrates in odontoblasts, where it remains for weeks.

300 y stage ameloblasts but could be detected in odontoblasts, while transition-stage and maturation-stag