ライフサイエンスコーパス: only a single

1 nts were included as a control group and had only a single (111)In-girentuximab injection and scintig

2 We find that RAG1/2 binds only a single 12RSS or 23RSS and reserves the second DNA

3 all predicted secondary structural elements, only a single 15-nt stem-loop showed a strong correlatio

4 n a subset of bacteria and archaea, contains only a single 6-TM domain and functions as a tetramer.

5 th OR and OL are tripartite, the presence of only a single active CI binding site in one of the two o

6 -state models where the receptor can achieve only a single active state.

7 For most outcomes, there was at most only a single adequately adjusted study, which usually f

8 Because (89)Zr has a half-life of 78 hours, only a single administration of tracer was needed to obt

9 e exists demonstrating the same effect after only a single administration.

10 e family history compared with families with only a single affected proband (singleton).

11 strains of the 'deep clade' ecotype contain only a single alginate lyase in a separate 7 kb island.

12 sease, and current vaccine strategies target only a single alphavirus species.

13 However, apoE4 differs from apoE3 by only a single amino acid at position 112, which is argin

14 on assays, isoallelic strains that varied by only a single amino acid in CovS, and transcriptome anal

15 trated in the previous studies, to targeting only a single amino acid without compromising the intens

16 Furthermore, lampreys express only a single, ancestral corticosteroid receptor (CR).

17 lification in the system hardware, requiring only a single antenna to achieve DoA estimation.

18 Only a single antibody (Cosmo Bio Co) detects PHLPP1alph

19 We found that only a single antibody molecule can be bound to each prM

20 There is no vaccine and only a single approved drug that provides no benefit for

21 hic purification of products is avoided, and only a single aqueous workup is performed.

22 l "primer." Thus, these studies suggest that only a single arabinan chain attached near the middle of

23 in the general population and typically used only a single assessment of diet.

24 an and Chinese ancestries generalized, while only a single association previously discovered in a peo

25 to sensors with uniformly oriented VHH (with only a single azide group).

26 ticularly challenging due to the presence of only a single base mismatch in the middle of the 251 bas

27 allele differs from the wild-type allele at only a single base pair.

28 of the let-7 microRNA family that differ in only a single base position.

29 s in hexane or chloroform self-assemble into only a single bcc superlattice.

30 fly genome encodes three proteins that bear only a single BEN domain ("BEN-solo" factors); namely, I

31 rd-occluded and inward conformations present only a single beta-d-glucose interaction site.

32 nals: The first considers DNA fragments with only a single binding event, whereas the second consider

33 ue culture, or in vitro; typically addresses only a single biochemical function of a protein; and is

34 cost manufacturing, but they tend to measure only a single biomarker and provide no information about

35 The reliance on only a single bp with the 3' nucleotide of the acceptor

36 were determined in the same experiment using only a single bulk concentration of SBN.

37 cillations in response to Ca(o) , initiating only a single [Ca(2+) ](cyt) spike.

38 ery strongly suggests that the possession of only a single calcareous shell plate and the presence of

39 ions on other known kinesins, which can bind only a single "canonical" site per tubulin dimer.

40 etric reactions and the most popular install only a single carbon rather than uniting larger fragment

41 By contrast, to date, only a single case of naturally acquired P cynomolgi has

42 ed conditions in clinical medicine, there is only a single case report of a patient with MS and HIV t

43 threshold concentration, BMP4 gives rise to only a single cell fate, contrary to its role as a morph

44 labeling of select interneurons--frequently only a single cell in a large region.

45 em cell-derived cells because of the loss of only a single cell type-the insulin-producing beta-cell.

46 allenged multiple times by the same route or only a single challenge is performed.

47 e in a simulated world and are supplied with only a single channel of communication.

48 us, however, on maternal effects that affect only a single character, whereas the evolution of matern

49 ibit up-regulation of two products even when only a single chemical reaction is addressed catalytical

50 Only a single chimpanzee in control groups, who had not

51 Only a single cholangiocarcinoma was misdiagnosed as cat

52 found that each painting probe hybridized to only a single chromosome in all other five species, sugg

53 Most previous studies have investigated only a single clotting protein and lipid composition and

54 ne in rodents has eight non-coding exons and only a single coding exon (IX).

55 hic images can be realized in real time with only a single coding metasurface.

56 Only a single colony was recovered from 1 of 60 C57BL/6

57 V variants revealed that their genomes share only a single common difference from that of CpGV-M, whi

58 ecially at wide scattering angles, even when only a single conformational state is significantly popu

59 ith a large stabilization energy difference, only a single conformer was found (BEA, LTA and MFI).

60 Multi-species sequence comparisons revealed only a single conserved non-coding element, in the lampr

61 ese phenotypes were exacerbated in mice with only a single copy of p300 or CBP expressed in islets.

62 utations that improve virus replication with only a single copy of rhtrs1 to evolve, we passaged rhtr

63 sage, we isolated two viruses that contained only a single copy of rhtrs1 yet replicated as well as t

64 Because cohesin contains only a single copy of Smc3p or Mcd1p, these examples of

65 ely on nonhomologous end joining (NHEJ) when only a single copy of the genome is available and mainta

66 oach could detect the BCR-ABL biomarker when only a single copy was present, although multiple screen

67 Twenty-three patients received only a single course of HDCT because of progressive dise

68 orly known clades, previously represented by only a single cranium and isolated jaws and teeth(1-5).

69 able fluorescent states, as long as there is only a single dark state.

70 nt compositions, on the same Si wafer, using only a single deposition process and a single anneal pro

71 ather and generate clinical data, a focus on only a single disease or treatment, and high development

72 mediate partially reduced species containing only a single disulfide bond were also generated, from w

73 ndependence would be achieved routinely with only a single donor.

74 r compact two-electron spin qubits requiring only a single dot and no additional magnetic field gradi

75 rs for oral application in the past decades, only a single double prodrug with very modest oral bioav

76 sequential imaging of multiple targets using only a single dye and a single laser source.

77 nding orbital of the radical cation contains only a single electron, giving rise to an elongated C-C

78 oupling of two fluorophores, our design uses only a single emitter, which simplifies ratiometric sens

79 reduce the bias problem caused by minimizing only a single energy function due to the very diversity

80 e distal and lingual cusps; this resulted in only a single enlarged cusp in the basin-like heel (talo

81 ged signal sequences were identical, or when only a single entity produced the variable sound sequenc

82 The reaction requires only a single equivalent of substrate and proceeds with

83 assification of three koala subspecies, with only a single evolutionary significant unit supported.

84 Some forms of associative learning require only a single experience to create a lasting memory [1,

85 mans have significant scale-invariance after only a single exposure to a novel object.

86 Upon repeat testing, only a single false-positive MCR-2 producer remained, as

87 known to be derived from aerobic organisms, only a single family of polyketides has been identified

88 escales are observed in aqueous solution but only a single, faster decay in the soft drink matrix.

89 nup graphene nanoflakes can be fabricated by only a single femtosecond laser pulse, which is efficien

90 al recessive condition described thus far in only a single First Nations population and causes intrau

91 Using only a single fitting parameter that accounts for experi

92 normative view that the motor system selects only a single, flexible motor plan, optimized for uncert

93 binding state was probed simultaneously with only a single fluorescent label.

94 unresolved dark states, as long as there is only a single fluorescent state, or if there are differe

95 resulted in several absorbing components and only a single fluorescing component.

96 dict where motifs are likely to appear using only a single-force parameter and uncover the localizati

97 First, while to date only a single form of body-care-related tool use has bee

98 alues are observed in offshore environments, only a single formation, evidently the shallowest, shows

99 mental data from Salmonella typhimurium with only a single free parameter.

100 4-10), probing the properties of the atom at only a single frequency.

101 brane vesicles, a variant of CTxB containing only a single functional GM1 binding site exhibits signi

102 ible for antibiotic-associated diarrhea, has only a single functional sortase (SrtB).

103 of the actin nucleator Cobl, despite having only a single G-actin-binding Wiskott-Aldrich syndrome p

104 apid melt growth technique that comprises of only a single Ge growth step and a single anneal step.

105 In five loci, only a single gene was involved: FURIN, TSNARE1, CNTN4,

106 in human erythroid cells directly activates only a single gene, the NuRD component CHD4.

107 Only a single gene, TREML4, was upregulated in CAC cases

108 y in their gene expressions, despite forming only a single genetic cluster.

109 Indices producing only a single global statistic (7 of the 8 indices) are

110 iocins across the outer membrane, containing only a single globular ferredoxin domain connected to it

111 A mutant CTxB capable of binding only a single GM1 fails to generate curvature either in

112 lso remarkable in that they are derived from only a single heavy atom change in the structure.

113 charides in length, are capable of accepting only a single heavy chain (HC) from inter-alpha-inhibito

114 ll population of alphabeta dimers containing only a single heme ligand and having a dioxidation modif

115 Of six probands with only a single heterozygous mutation in TYR, all were fou

116 evel of reported missing heritability, where only a single heterozygous mutation is found in TYR.

117 d periodic acid-Schiff staining, even though only a single histologic section for each PEC marker was

118 Only a single homolog to the cargo carrier protein Unc11

119 nd pandemic control, a vaccine that requires only a single immunization would be optimal.

120 efficiently induced antibody responses after only a single immunization.

121 Most basic and translational studies utilize only a single inbred mouse strain.

122 55% of 3,659 different genotypes occurred in only a single individual.

123 The key study limitation was that only a single infant sample was collected to minimize ve

124 When a cell was infected by only a single infectious particle, variation in the kine

125 neously activates at least two NLRs, whereas only a single inflammasome complex is formed in a macrop

126 died in "well-controlled" environments where only a single input is varied, potentially missing impor

127 -graft group, 13.9% of the patients received only a single internal-thoracic-artery graft, and in the

128 tion through interferometric measurements of only a single ion in the chain.

129 o achieve silencing are inefficient, pumping only a single ion per photon across the cell membrane ra

130 lated non-heme diiron proteins, but revealed only a single iron ion in the active site.

131 r dendrites ensures self-avoidance even when only a single isoform is expressed.

132 tical cohort of 10,000 patients who received only a single kidney transplant and terminated when all

133 at vanishes in the ultra-quantum limit, when only a single Landau level is occupied.

134 small sample size, retrospective nature, and only a single lapse being evaluated.

135 ering reduces when the pores can accommodate only a single layer of ions.

136 The lens-loaded cavity requires only a single lens and output port, making the hardware

137 More importantly, APOM uses only a single lens near the sample to achieve selective-

138 post-diagnostic interventions assuming that only a single lesion progresses to invasive carcinoma du

139 spontaneously even in a membrane containing only a single lipid component.

140 uish between hemifusion and full fusion with only a single lipid dye, thereby freeing up a fluorescen

141 d locations, transistor fabrication requires only a single lithographic step.

142 existing location prediction systems assign only a single location per protein.

143 ps within this group have been studied using only a single locus (the rRNA operon), leaving the origi

144 ore factor co-localise in each chromosome at only a single locus, which corresponds with previously m

145 antimicrobial-exposed patients, and requires only a single LRT specimen.

146 th WT as well as Lys-48-ubiquitin, which has only a single lysine residue at position 48.

147 Although only a single MAGE gene exists in lower eukaryotes, the

148 he predominant oligomeric forms of MBL carry only a single MASP homodimer.

149 ative as, unlike the double-spike procedure, only a single mass spectrometric measurement is required

150 In angiosperms, only a single maturase has been retained in the mitochon

151 Invertebrates generally have only a single MBD protein, MBD2/3, that does not always

152 vironments are still poorly understood, with only a single member of this genus (Ca. N. devanaterra)

153 ich may be quite numerous, or may consist of only a single member.

154 ugh complex "pipelines", even in cases where only a single metabolite or peak is of interest.

155 on of dinuclear palladium complexes, wherein only a single metal center is directly involved in the c

156 uce YSNs that cannot be obtained directly by only a single method.

157 H3 K79 methylation, which is carried out by only a single methyltransferase, disruptor of telomeric

158 In only a single MHCI-peptide combination, trimming of an H

159 implest of Type IV pilus systems and possess only a single minor pilin.

160 nefits of amphibian embryology but crucially only a single Mix and Nodal gene required for the specif

161 r strategy is simple to implement, requiring only a single mixing step at room temperature for each o

162 tional systemic antimicrobial agents, having only a single mode or site of action, will not alleviate

163 Its biosynthetic gene cluster contains only a single-module polyketide synthase-nonribosomal pe

164 multidimensional grid methods, assures that only a single molar mass can be associated with a given

165 Although only a single molecule of alphaSNAP binds to a soluble f

166 ter if they are polymorphic than if there is only a single morph present in the population.

167 of Hfq-binding sRNAs but surprisingly target only a single mRNA, which encodes the outer membrane lip

168 average length of fatty acids-than FASs with only a single multifunctional version of each enzyme (i.

169 Most mutants carry only a single mutation.

170 -rabbit host jump over 40 years ago and that only a single naturally occurring nucleotide mutation wa

171 The last two decades have produced only a single new drug but have represented a renaissanc

172 ften can be assembled in a few contigs using only a single Nextera Mate Pair library of short reads.

173 In fact, only a single non-enzymatic domain within SypF, the HPt

174 % of GPR42 haplotypes differed from FFAR3 by only a single non-synonymous substitution and that the G

175 Var1 differs from those in the wild type by only a single, non-synonymous substitution (Gly734Glu) i

176 ntified in the TR transactivation assay, but only a single novel, direct agonist was found, the pharm

177 o-temperature approximation and assumed that only a single nuclear species was present at any given d

178 present systems start from units containing only a single nucleobase.

179 scriminate it from miR-10a, which differs by only a single nucleotide (12th base from the 5' end), an

180 ns, and an additional 12% (6/51) differed by only a single nucleotide across a 603-bp region of the p

181 fied peptides would need to reliably contain only a single O-glycosite.

182 as been studied in situations that comprised only a single object.

183 is almost always no replication; typically, only a single observation exists for a particular site o

184 data, especially when the data set comprises only a single observation of one network, often leading

185 This structure persists even when only a single OH group is present in the HD2O(+) isotopo

186 n AZ harbors 4 docked vesicles in human, but only a single one in rats.

187 elic variants (allelic-drive) resulting from only a single or a few nucleotide alterations.

188 n algae express many different OPR proteins, only a single orthologous OPR protein is encoded in the

189 We find only a single oscillatory component with no signatures o

190 Syntheses tend to employ only a single OSDA, but there are a few examples where t

191 Only a single OTU, TM7-3a, was found to increase with sl

192 Discussion: Although only a single outcome indicator goal (at least 10% annua

193 t and protein is turnover-dependent and that only a single oxygen is exchanged into the protein even

194 ls flowing through 5 different outlets using only a single pair of impedance electrodes, showing clas

195 through multiple microfluidic outlets using only a single pair of microelectrodes.

196 ning, in which the brain learns rapidly from only a single pairing of a stimulus and a consequence.

197 rther show that in some cases, the data from only a single paramagnetic tag are sufficient for accura

198 , our single-layer model with CSN or DSN and only a single parameter achieved a prediction performanc

199 Only a single parasite (Haemoproteus nucleocondensus) wa

200 In trees, vertices may have only a single parent (ancestor), while networks allow fo

201 ection is within, or among, families sharing only a single parent (half-siblings), which is common in

202 However, only a single pathway for Np(4)N signaling has been deli

203 In contrast, only a single pathway has been identified for C. parvum

204 e disorders detected, 39 (59%) were found in only a single patient.

205 e central cavity of the BK channel, and that only a single PAX molecule can interact with the BK chan

206 ing site via the central cavity and involves only a single PAX molecule would be consistent with bind

207 ssion followed by mass spectrometry revealed only a single peptide expressed from both the cryptic OR

208 wed consistent binding in this region but to only a single peptide.

209 the enteric pathogen Vibrio cholerae, encode only a single PG amidase, AmiB.

210 ring human pancreas development, we detected only a single-phase of Neurogenin 3 (NEUROG3) expression

211 e population of individuals that can express only a single phenotype.

212 p38alpha bearing only a single phosphocysteine (pCys) as a mimic of pThr

213 putational periscopy technique that requires only a single photograph captured with an ordinary digit

214 present a mechanism by which organisms with only a single photoreceptor, which have a monochromatic

215 -free, rapid, highly sensitive, and requires only a single pipetting step.

216 nts in the majority of vaccinees compared to only a single placebo recipient.

217 measures, and they had to rely on data from only a single point in time (2000-2001).

218 is designed with the two criteria of having only a single point of S-S scission and maximizing the r

219 amily in the 1990s, the de novo synthesis of only a single polycyclic furanobutenolide-derived cembra

220 flect across the full visible spectrum using only a single polymer (M(n) = 290 kDa) by altering the i

221 le isoforms are expressed at the mRNA level, only a single polypeptide that co-migrates with the huma

222 sing a shorter huntingtin variant containing only a single polyproline tract, is shown to be on the s

223 mpared with 82.8% for PLS-DA) occurred using only a single pre-processing step.

224 The human gene uses only a single promoter, whereas the mouse uses two: P2,

225 Whereas most viruses require only a single protein to bind to and fuse with cells, he

226 In contrast, the B-type CcO uses only a single proton input channel for all consumed and

227 s, but current biochemical techniques detect only a single proximity partner per probe.

228 e yield of each step is >91% and it requires only a single purification step.

229 l-N-arylindoles in high yields followed with only a single purification step.

230 The Streptomyces coelicolor genome encodes only a single putative lipoate ligase.

231 , most of these approaches enable the use of only a single reagent at a time.

232 son to that of systems capable of exploiting only a single recognition-mediated pathway.

233 Because there is only a single redox moiety the faradaic process occurs a

234 ain to the oxidase domain, which reveal that only a single reductase domain participates in electron

235 ory support compared with infants exposed to only a single repeat course.

236 of the entire fragment-ion series instead of only a single reporter ion.

237 Even when the TMDs differ in length by only a single residue, hydrophobic mismatch can segregat

238 d, Form III of this drug despite there being only a single resolved form for almost 70 years.

239 electronic properties, despite differing by only a single ring in the link between the PDI units.

240 bullet-shaped GroEL/GroES complexes in which only a single ring is capped by GroES interact with the

241 ctively, although half of all CRUs contained only a single 'rogue' RyR.

242 osed to explain this result by assuming that only a single row of vortices is allowed inside a nanowi

243 Fourth, only a single sample incubation step is required before

244 ly, we measured quantifiable PBDE burdens in only a single sample of predaceous ground spiders from t

245 DeepCyTOF requires labeled cells from only a single sample.

246 red capsid structures on a large scale using only a single screening round in vivo.

247 ts and external presses simultaneously, with only a single sensor in real time.

248 y a few species stably to coexist, including only a single shade tolerant.

249 quid crystalline behavior in spite of having only a single side chain.

250 Alternatively, if only a single site is involved, GpIbalpha may serve as a

251 These simple pathways with only a single SK are not well suited to making complex d

252 the periphery of the bulk MOF crystals with only a single SMM molecule isolated in the transverse di

253 ric analyses support the idea that there was only a single species of middle to late Pleistocene NWSL

254 ixture of two DNA molecules, each possessing only a single specific site, indicate that transfer betw

255 me-point (STP) dosimetry, particularly using only a single SPECT scan, is on the rise.

256 ermy and ensure that eggs normally fuse with only a single sperm.

257 pairing, reactivity modes can be missed when only a single spin-pairing/orbital interaction descripto

258 ared with the CAR(tcp):RXR.SRC1, which binds only a single SRC1.

259 thography for the print of the features, and only a single-step surface pretreatment is needed.

260 structures have been available in detail for only a single strain (GI.1).

261 g disease was consistent with infection with only a single strain.

262 whereas 2 women had acute HEV detectable at only a single study visit.

263 in variants from the ChH1A cluster, whereas only a single substitution in antigenic site Sa (G155E)

264 Remarkably, to date only a single subtype of inhibitory neuron has been docu

265 thereby accounting for the observation that only a single subunit of the p66 homodimer precursor is

266 RNA polymerase III (Pol III) that differ in only a single subunit, with POLR3G in one form (Pol IIIa

267 vents fits the data better than a model with only a single successful reactivation event.

268 y few SNVs (average of 5.9 per megabase) and only a single SV.

269 Nine (64.3%) had only a single symptom.

270 This requires building only a single system-specific construct by placing a tar

271 indicate that modification or disruption of only a single target nucleosome results in significant c

272 -2 in a single tube within 40 min, requiring only a single temperature control (62 degrees C).

273 n studies of virus epidemiology that rely on only a single test at symptom onset.

274 elix, whereas prokaryotic SemiSWEETs contain only a single THB and require homodimerization to form t

275 ith escape mutants were 100% protected after only a single therapeutic dose of the antibody used to g

276 were compared to a model compound containing only a single thiophene-substituted quinoxaline ring.

277 urate short-term forecasts, even while using only a single time series from the multivariate system.

278 C. trachomatis phylogeny show that there is only a single trachoma-causing clade, which is distinct

279 hieved without cumbersome circuitry and with only a single transducer, thus significantly reducing sy

280 domains, whereas metazoan Mitofusins contain only a single transmembrane domain.

281 utations in CCHFV recovered from ticks after only a single transstadial transmission, whereas none we

282 udy was that dexamethasone patients received only a single treatment during the 6-month study.

283 gm, memory requirements are minimized (often only a single tree or sequence in memory at any instance

284 s subsequent fear conditioning training with only a single trial.

285 to contextual information alone, even after only a single-trial conditioning procedure, and that sle

286 either model complexes containing no tRNA or only a single tRNA, or complexes where EF-G was directly

287 This requires only a single tunnel contact to the nanoparticles thus s

288 s, most glycomics databases allow storing of only a single type of experimental data.

289 Each recombinant BaF3 cell line expresses only a single type of fibroblast growth factor receptor

290 ing adenine and cytosine base editors induce only a single type of modification, limiting the range o

291 tability with their surroundings, respond to only a single type of stimulus and are unable to achieve

292 ut how Bre1 directs Rad6 toward transferring only a single ubiquitin to a specific lysine residue.

293 n pigment composition of any model wine with only a single UPLC-MS/MS analysis.

294 The device requires only a single user step and delivers (i) the sample, (ii

295 lation of var gene expression, ensuring that only a single var gene is expressed at a time while the

296 robands had no variants and six probands had only a single variant, including four with a heterozygou

297 cular phenotypes in model systems expressing only a single VEGF isoform.

298 sure doses in humans that typically transmit only a single virus.

299 last ablation, VT-free survival was 71% with only a single VT episode in additional 9 patients (15%).

300 h diastereoselectivity during catenation, as only a single (Z)-isomer is formed.