ライフサイエンスコーパス: optimistic

1 uman studies suggest there are reasons to be optimistic.

2 seen early may not be real or may be overly optimistic.

3 ial stages; but the preliminary data make us optimistic.

4 acute renal failure, there are reasons to be optimistic.

5 ctations were lower, while patients remained optimistic.

6 increasing CO2 in the atmosphere, are unduly optimistic.

7 These results are probably overly optimistic.

8 rformance during development is often overly optimistic.

9 epidemics during the ART era might have been optimistic.

10 Are there reasons to be optimistic?

11 r percentage of respondents are also falsely optimistic (15% of all respondents).

12 l group was less than 9% even under the most optimistic a priori assumptions, and further trial accru

13 erence, poor participant retention, and over-optimistic AAA growth reduction targets.

14 Parents of children with cancer are overly optimistic about chances of cure but not about other out

15 Parents tend to be overly optimistic about cure when physicians have little confid

16 I am moderately optimistic about improving predictions of large events f

17 scourse routinely assumes that Americans are optimistic about mobility prospects in society.

18 assical Lewis structure nevertheless make us optimistic about the chances of detecting and even isola

19 Not only are we more optimistic about the current state of the art in behavio

20 rms "pessimists" are often considerably more optimistic about the prospects for progress in moral inq

21 ford such high rate accelerations, making us optimistic about the prospects of designing more sophist

22 ding suggests that there is reason to remain optimistic about the therapeutic potential of these drug

23 In my view, however, they are too optimistic about the versatility of the paradigm and, mo

24 In contrast, transplant recipients were optimistic about their ability to age successfully, beli

25 However, even if we are optimistic about their source (i.e., reasoning), some pe

26 ding 29 (23%; 95% CI: 16, 30) with an overly optimistic abstract, 10 (8%; 96% CI: 3%, 13%) with a dis

27 , we show that wild New Caledonian crows are optimistic after tool use, a complex, species-specific b

28 confidence interval [CI], 70 to 74) with the optimistic analysis and 51% (95% CI, 49 to 52) with the

29 Corresponding figures for the optimistic analysis were 9%, 12%, 5%, and 7%.

30 lysis") or assumed negative for metastases ("optimistic analysis").

31 rs, 42.7 [6.9] years), 196 (89.1%) preferred optimistic and 24 (10.1%) preferred pessimistic framing

32 ernal age and performed with the use of both optimistic and conservative methods.

33 tives cost <$50 000/life-year only under the optimistic and intermediate scenarios.

34 les over the last 10 years has led to a more optimistic and interventionist approach to the surgical

35 Fifth, he was perceived as cautiously optimistic and judiciously positive as he interacted wit

36 ely tree-species extinctions under published optimistic and nonoptimistic Amazon scenarios.

37 ee species in the Brazilian Amazon under the optimistic and nonoptimistic scenarios, respectively.

38 l of these common species persist under both optimistic and nonoptimistic scenarios.

39 Consequently, many expectations are wildly optimistic and over-estimate the speed and extent of the

40 ere investigated at 1481 sites in Iran under optimistic and pessimistic climate heating scenarios for

41 producibility Project: Psychology data, both optimistic and pessimistic conclusions about reproducibi

42 s between the amount of habitat converted in optimistic and pessimistic land-use scenarios, highlight

43 ation areas with associated CO2 emissions in optimistic and pessimistic scenarios.

44 his review, the evidence for and against the optimistic and pessimistic viewpoints is discussed.

45 l assumptions, that is, intermediate between optimistic and pessimistic, is estimated to be approxima

46 All are optimistic and predict enormous positive impact on scien

47 ations of "5% chance of surviving" were more optimistic and showed substantial variability (median, 9

48 not only generous, but are also consistently optimistic and uncompromising.

49 nstruction of urinary diversion (ECUD) looks optimistic as favored by the patients and surgeons alike

50 We are cautiously optimistic, as the field of MAGL inhibitor development t

51 Their very optimistic assessment is limited by statistical misconce

52 n average ratio less than one indicates more optimistic assessments with HRs.

53 <0.1%) did not occur by 30 years, even with optimistic assumptions about the linkage rate.

54 creening may be reasonable in younger men if optimistic assumptions consistent with existing observat

55 Under the optimistic assumptions in the primary analysis, the inci

56 Although optimistic assumptions would be required to achieve cost

57 of $2700/year of life saved, and may, under optimistic assumptions, achieve cost savings.

58 With optimistic assumptions, they can turn WWTPs into net ene

59 Even under such optimistic assumptions, we find that the widespread depl

60 hepatology providers is predicted even under optimistic assumptions.

61 with using triple therapy first, even under optimistic assumptions.

62 nces occurred outside outpatient visits; (2) optimistic attitudes from transplant teams hindered the

63 style were less depressed than those with an optimistic attributional style and the nonpregnant group

64 ttributional style but not for those with an optimistic attributional style.

65 as an energy resource have often been overly optimistic, based in part on its very high methane conte

66 We suggest that their conclusion is overly optimistic because of a limited selection and interpreta

67 s, correlations, etc.) are frequently overly optimistic because the training sets are dominated by pa

68 S180 animals failed to develop the same more optimistic behavioural profile as controls in response t

69 for this type of prognosis discordance, and optimistic belief difference was present for 94 of 173 p

70 .94; P = .03), and physician perception with optimistic belief differences (OR, 2.32; 95% CI, 1.10-4.

71 Optimistic belief differences were analyzed as a subgrou

72 ind ways to target both misunderstanding and optimistic belief differences.

73 Despite our optimistic belief that we would behave honestly when fac

74 actors that place parents at risk for overly optimistic beliefs about prognosis.

75 However, optimistic beliefs can at times appear surprisingly resi

76 ic of some enthusiasts focuses instead on an optimistic best-case scenario of the future of DNA scien

77 Optimistic bias (better learning of positive relative to

78 Conversely, a lack of this optimistic bias in depression and social anxiety may per

79 Both groups of patients exhibited an optimistic bias in that they considered themselves to be

80 y measure, with bootstrapping to correct for optimistic bias.

81 cy measure with bootstrapping to correct for optimistic bias.

82 fold cross-validation to limit the effect of optimistic bias.

83 nostications by surrogates arise partly from optimistic biases rather than simply from misunderstandi

84 As optimistic biologists passionate about the future of our

85 The analysis also reveals that optimistic business-as-usual scenarios in the U.S. will,

86 wer C statistics, bootstrapping tended to be optimistic but with lower absolute and mean squared erro

87 nd the prospect of eradicating malaria is an optimistic, but reachable, target in the 21(st) century.

88 hat the initial estimates of efficacy may be optimistic, but the overall benefits of the procedure re

89 Overall, the outlook is optimistic, but there is still some way to go.

90 In an optimistic case, liquid hydrogen (LH2) and power-to-liqu

91 ed from the National Research Council (2013) optimistic case.

92 Optimistic claims about the ability of recently proposed

93 were derived experimentally, leading to over-optimistic classifier performance estimates.

94 The optimistic climate-land-use projection (Sustainability a

95 Even with the most optimistic CO2 emissions scenario (Representative Concen

96 CD45RA+ CD4+ T cells are consistent with the optimistic conclusions that (i) renewal mechanisms have

97 Although these studies report optimistic conclusions, we identify troubling indication

98 Here we show that the most optimistic cost-effective demand-side solution can reduc

99 gh risk for hemorrhage or meet the following optimistic criteria: prevent greater than 32% of major b

100 ning future space-based telescopes, but that optimistic definitions may be useful in interpreting the

101 binations of evidence-based interventions at optimistic (drawn from best available evidence) or ideal

102 of vital organs for transplant predicted by optimistic early estimates.

103 oritism, this favoritism manifests as overly optimistic earnings forecasts after corporate site visit

104 cases representing conservative, medium, and optimistic engine-out emission reduction benefits are an

105 thods to detect deletions, thus providing an optimistic estimate of SV detection performance as the S

106 x traits; when applied to epilepsy, our most optimistic estimate suggests that at least 400 variants

107 very low probability, less than 10% in most optimistic estimate, to survive without facing a catastr

108 oductivity is low, which lies in contrast to optimistic estimates based on regional statistical analy

109 We find that with optimistic estimates for the stall stress of actin gel g

110 studies that may provide misleading, overly optimistic estimates of aging changes.

111 ter precision at small x, leading to falsely optimistic estimates of detection and quantification lim

112 Even with optimistic estimates, few Atlanta MSM (15%) are projecte

113 Optimistic estimation of the C statistic is a frequent p

114 Our objective was to determine the causes of optimistic expectations about prognosis among surrogates

115 Optimistic expectations about prognosis by surrogate dec

116 all, 45% of surrogates (95% CI, 38-51%) held optimistic expectations about prognosis, which arose fro

117 ents with advanced illness often have overly optimistic expectations about prognosis.

118 Our findings indicate overly optimistic expectations about return home and unmet pall

119 atients with ESKD may harbor unrealistically optimistic expectations about their prognoses.

120 Optimistic expectations by surrogates were associated wi

121 ntial outcomes, and surrogates' unreasonably optimistic expectations seem to be potentially modifiabl

122 multivariable regression to examine whether optimistic expectations were associated with length of s

123 determined the proportion of surrogates with optimistic expectations, defined as a prognostic estimat

124 Even using the most optimistic expert judgements, the lower bound on time is

125 ower bound on that figure, obtained using an optimistic exposure scenario, was 0.3%.

126 ns and then they act according to their most optimistic forecast.

127 unchanged when pessimistic framing followed optimistic framing (mean difference, 2.15; 95% CI, 0.91

128 d video, state anxiety scores decreased when optimistic framing followed pessimistic framing but rema

129 Optimistic framing may lead to more realistic expectatio

130 The primary factor differentiating optimistic from pessimistic projections was the degree t

131 erns over disease progression or dying, used optimistic future talk to address patient concerns, or e

132 )-approximately 3 times larger than the most optimistic GIF calculated here.

133 ep ahead of the beta-lactamases is an overly optimistic goal; the best that can be expected is to avo

134 atients; 2) surrogate stress and anxiety; 3) optimistic health expectations; 4) poor planning for med

135 There are reasons to be optimistic, however, as emerging therapies have shown pr

136 This may be overly optimistic, however, given that HIV-1 envelope proteins

137 Even under our most optimistic HR scenario, the reduction in TB incidence fr

138 diate grade sandpaper): a rat was classed as optimistic if it chose the bowl ordinarily associated wi

139 t-resuscitation patients but remained overly optimistic in do-not-attempt-resuscitation patients.

140 hat these effect sizes are likely to be over-optimistic in every empirical study that we found that r

141 iour in the elevated plus maze and were more optimistic in the cognitive bias test.

142 ng statistics for such estimates are falsely optimistic in their assessment of the estimation precisi

143 n E efficacy, in hindsight, have been overly optimistic in their expectation that a vitamin could rev

144 ficantly pessimistic in patients without and optimistic in those with do-not-attempt-resuscitation or

145 orest carbon sink persistence are likely too optimistic, increasing the need to curb greenhouse gas e

146 However, highly optimistic individuals exhibited reduced tracking of est

147 nature of probability may lead to an overly optimistic interpretation of new evidence.

148 The impact of optimistic interventions including immediate ART initiat

149 ces for biomarker development are published, optimistic investigators may not appreciate the statisti

150 faster than birds in low-complexity pens-an optimistic judgement bias, suggesting the former were in

151 an expectation of reward under ambiguity-an "optimistic" judgement bias, suggesting positive emotiona

152 ger in practice than we estimate here due to optimistic laboratory vehicle efficiency tests used in p

153 sed censorship causes firms to become overly optimistic, leading to irrational booms in adoption.

154 ptom onset to first injection predicted less optimistic letter gains in unadjusted and adjusted model

155 s, reflecting more pessimistic-like and less optimistic-like behavior, respectively.

156 s depressed individuals tend to adopt a less optimistic-like interpretation of ambiguous appetitive s

157 he reader up, giving the opposing view of an optimistic, limitless future a voice.

158 he reader up, giving the opposing view of an optimistic, limitless future.

159 up, giving voice to the opposing view of an optimistic, limitless future.

160 es that can resist invasion by defectors are optimistic (make high initial offers), generous (always

161 tients referred to a phase I clinic remained optimistic, many had discussed a living will, medical po

162 hysician as trustworthy vs 39 after the less optimistic message (P = .03).

163 More research is needed in structuring less optimistic message content to support health care profes

164 message type: 63 patients observing the more optimistic message ranked the physician as trustworthy v

165 ician discussing treatment information (more optimistic message vs less optimistic message) with a pa

166 information (more optimistic message vs less optimistic message) with a patient with advanced cancer.

167 optimistic vs an equally empathetic but less optimistic message.

168 and preferred physicians who provided a more optimistic message.

169 Optimistic methods assumed that patients who did not ret

170 The most optimistic mitigation of noise and contaminants would ma

171 Under optimistic model assumptions, oral pre-exposure prophyla

172 s for about 30 days per year, while the most optimistic model results suggest that existing land cult

173 ian analysis included four different priors (optimistic, neutral, null, and pessimistic) for mortalit

174 health care professionals in delivering less optimistic news.

175 But, on a more optimistic note, we show that sufficiently high levels o

176 IAPP) and leptin (LEP) analogues was once an optimistic option in treating obese animals and patients

177 Additionally, we study the effects of optimistic or pessimistic biases in individual beliefs a

178 om underpowered studies, resulting in overly optimistic or unwarranted conclusions.

179 We argue that an optimistic outlook by the nuclear medicine community is

180 new peptide radiopharmaceuticals present an optimistic outlook for clinical translation into recepto

181 d in the last year has continued the initial optimistic outlook for human papillomavirus vaccination

182 scular complications have resulted in a more optimistic outlook for people with diabetes.

183 An optimistic outlook should be cultivated to promote civic

184 ortant in MSP1-mediated immunity provides an optimistic outlook that a subunit MSP1 vaccine may be ef

185 In 152 accurate or optimistic parents, we determined factors associated wit

186 top quartile) versus least (bottom quartile) optimistic participants had a 24% increased likelihood o

187 Optimistic perception of illness and greater self-effica

188 A more optimistic perceptual set, despite equivalent objective

189 Standard cross-validation led to over-optimistic performance estimates due to the presence of

190 Optimistic, pessimistic, and baseline projections of the

191 ates of the probability of survival with the optimistic/pessimistic forecast given in the case.

192 for SARS-CoV-2 RATs might provide an overly optimistic picture of the sensitivity of a test.

193 outcomes are random, and we note examples of optimistic prediction in the literature.

194 Despite optimistic predictions on the eventual end of COVID-19,

195 will be more depressed after childbirth than optimistic pregnant teenagers.

196 Our results offer an optimistic premise that effective local management, alon

197 years per 1000 patients were gained from the optimistic prior derived posterior HR and a 10% incidenc

198 benefit using Bayesian regression models (an optimistic prior for the primary outcome and neutral pri

199 Using an optimistic prior, posterior median odds ratios were 0.61

200 rt among dying patients whose surrogates had optimistic prognostic expectations compared with those w

201 According to the most optimistic projections, it will take more than a year to

202 Although there are optimistic proponents for each strategy, the lack of wel

203 a problem, we developed a new method called Optimistic Protein Assembly from Reads (OPAR).

204 ross-validation procedure leads to an overly optimistic quality estimate, while the density-weighted

205 ed to empirical optimism, or what May calls "optimistic rationalism." I place May's book in the liter

206 developed for three climate change scenarios-optimistic (RCP2.6), moderate (RCP4.5), and pessimistic

207 because adaptive theories are generally more optimistic regarding prospects for medical intervention

208 roduction is observed within the century for optimistic regeneration of reserves and a collection-rec

209 rk datasets, which lead to biased and overly optimistic reported performances.

210 Finally, early optimistic reports of the use of bisphosphonates in juve

211 nity, high levels of activity, intelligence, optimistic resilience, and flexibility.

212 Relatively optimistic responses were more common among parents and

213 rsifies, do previous findings present overly optimistic restoration expectations?

214 looked in ML studies but will result in over-optimistic results and misinterpreted variable importanc

215 skepticism that U.S. studies will yield the optimistic results that have characterized the European

216 n of biofortified rice for white rice in the optimistic scenario (20 ppm and 70% substitution) decrea

217 Under our optimistic scenario (OPT) we find 15% and 47% adoption o

218 Given this optimistic scenario and given the prospect of rigorously

219 However, even in the most optimistic scenario arrival screening will miss the majo

220 Compliance with the UK and optimistic scenario could avert approximately an additio

221 to decrease slightly by 2050 under the most optimistic scenario of land-use change and to substantia

222 In an optimistic scenario, assuming a 35% 5-year PFS, tisagenl

223 In an optimistic scenario, assuming a 40% 5-year progression-f

224 pessimistic scenario to $40.0 billion in an optimistic scenario, based on changes in US cuts.

225 Even under the most optimistic scenario, we found continued declines in near

226 n approximately 37% loss rate even under the optimistic scenario.

227 -effective interventions, while only certain optimistic scenarios (low coverage of 5% and some or hig

228 For the 2024 to 2025 season, optimistic scenarios of high immunization coverage (50%

229 Under more optimistic scenarios of reduced CO2 emissions, calcifica

230 1 g CO(2) equiv/kWh, whereas pessimistic and optimistic scenarios provide extreme values of 5.4-122 g

231 Even in the most optimistic scenarios, vaccine shortages will likely occu

232 Even under optimistic scenarios, we conclude that only a small frac

233 uitable area (> 90%) in both pessimistic and optimistic scenarios.

234 Even if a relatively optimistic schedule of future capacity addition is met,

235 Even in such optimistic settings, no polymerization of RNA longer tha

236 ampion PCE of over 20% was yielded under the optimistic simulation conditions.

237 Among "optimistic" simulations in which sexual transmission was

238 Even under the most optimistic sluicing scenario, sediment load at the Mekon

239 Even under the most optimistic socioeconomic scenarios (excluding food waste

240 Economic modelling suggests that even under optimistic socioeconomic scenarios future supply will be

241 s from our transect was twofold greater than optimistic soil carbon gains achievable from agricultura

242 ings show that the gene transfers provide an optimistic solution to the insufficiencies of the intrin

243 One version offered optimistic survival forecasts; the other, pessimistic fo

244 study are significantly higher than the most optimistic survival rates in the medical literature, and

245 The majority of parents (61%) were more optimistic than physicians about the likelihood of cure.

246 7.0%]; P = 0.23) and were substantially more optimistic than results of a validated prediction model

247 d beliefs about the prognosis that were more optimistic than that of the physician, the most common r

248 ts conveying a high risk for death were more optimistic than the actual meaning (P < 0.001; generaliz

249 ognostic estimate that was at least 20% more optimistic than the physician's, then determined how fre

250 ime points, patients' expectations were more optimistic than their experiences.

251 rly all of them (155 of 161 [96%]) were more optimistic than their oncologists.

252 to participate in a phase I trial being more optimistic than those declining phase I participation.

253 projections of food security are often more optimistic than what historical yield trends would suppo

254 We are optimistic that a better understanding of these changes

255 There is good reason to be optimistic that approaches to block complement activatio

256 to have widespread practical utility, we are optimistic that deep learning-based structural modeling

257 pid pace of development in the field, we are optimistic that designer enzymes will begin to play an i

258 ch strategies to improve reliability, we are optimistic that fMRI can fulfill its potential as a clin

259 or phenylketonuria, experts in this area are optimistic that further public health benefits will foll

260 We remain optimistic that human therapeutic cloning is achievable

261 The results to date lead us to be optimistic that new candidate vaccines could soon be con

262 essful bariatric surgery, gives reason to be optimistic that novel precision medicines that mimic, en

263 modifiable disorder of motor control, we are optimistic that research will yield novel therapeutic av

264 From this pilot trial, we are cautiously optimistic that targeting the IL-6/IL-6R pathway could o

265 ferent neurodegenerative diseases, we remain optimistic that tau-targeting therapies will eventually

266 Overall, we are optimistic that the big-data revolution will vastly impr

267 to ameliorate disease, there is reason to be optimistic that the dibenzofuran-based inhibitors will d

268 udy of neural circuits provide reasons to be optimistic that the field is headed in the right directi

269 There is every reason to be optimistic that the wealth of knowledge about the molecu

270 Here, we present reasons to be optimistic that this new policy will be valuable for neu

271 Numerous stakeholders are optimistic that this strategy will improve healthcare qu

272 We are optimistic that, in a planned clinical trial, addition o

273 The more optimistic the inventor, the higher are the projected re

274 tinuing investment of telescope time, we are optimistic these uncharted atmospheres will be detected

275 e last 18 weeks of follow-up are maintained (optimistic), to $30 550 (95% CI, 30 503-30 597) per life

276 duce CO2 abatement costs even under the most optimistic trajectories for improvements in fuel efficie

277 Looking forward, we delineate an optimistic trajectory for polydiene waste management, ad

278 s that overestimate warming and gives overly optimistic uncertainty estimates.

279 s at higher risk for recurrence; however, an optimistic under-estimation of recurrence risk is a comm

280 These accounts are often wildly optimistic, understating outstanding challenges while tu

281 An 'optimistic' UPR output aims at restoring homeostasis by

282 t and is likely to be cost-effective if more optimistic vaccine scenarios apply.

283 Optimistic versus pessimistic vaccine-sentiment assumpti

284 e optimistic video as compared with the less optimistic video (median [interquartile range], 15 [5-23

285 er compassion scores after watching the more optimistic video as compared with the less optimistic vi

286 ctive interventions holds promise for a more optimistic view of neurocognitive status in later life.

287 his testing strategy can result in an overly optimistic view of the performance of an RNA-seq analysi

288 use of ineffective strategies and an overly optimistic view of the potential for ecosystem migration

289 The author summarizes the reasons for this optimistic view.

290 ymptom onset and first injection led to less optimistic vision gains and were associated with higher

291 "forest transition model" projects an overly optimistic vision of a future where increased agricultur

292 technologic and process innovations inspire optimistic visions.

293 ian compassion after being exposed to a more optimistic vs an equally empathetic but less optimistic

294 uli in a negative (pessimistic) or positive (optimistic) way.

295 akes and is frequently interpreted in overly optimistic ways in the literature.

296 about efficacy of these mechanisms have been optimistic, we lack detailed analyses of their expected

297 ell within each group, but tended to be over-optimistic when predicting bilingual language outcomes:

298 sus for the future of surgery leadership was optimistic while recognizing that the demands of chairma

299 to this definition, the picture is much more optimistic, with perhaps greater than 20% of overweight/

300 d molecular release platforms and provide an optimistic, yet critical perspective on the fundamental