ライフサイエンスコーパス: optogenetic stimulation

1 m light repetitively in the intact brain for optogenetic stimulation.

2 modulated vHPC-mPFC terminal activity using optogenetic stimulation.

3 s area reflects their choosing to experience optogenetic stimulation.

4 re-entrant AT (induced via rapid pacing) via optogenetic stimulation.

5 ng the intensity, duration, and frequency of optogenetic stimulation.

6 s temporal resolution by MRI with sensory or optogenetic stimulation.

7 ic acid and chronic activation of the ACC by optogenetic stimulation.

8 physiological recordings with electrical and optogenetic stimulation.

9 prediction, we aligned periodic tactile and optogenetic stimulation.

10 nce was achieved through subnetwork-specific optogenetic stimulation.

11 o be restored in a controllable manner using optogenetic stimulation.

12 ons, using closed-loop signal processing and optogenetic stimulation.

13 kisspeptin neurons in vivo using continuous optogenetic stimulation.

14 ronal network using continuous low-frequency optogenetic stimulation.

15 Three hours after SE onset, unilateral optogenetic stimulation (450nm, 25mW, 20-millisecond pul

16 as been reported on the response kinetics of optogenetic stimulation across different neuronal subtyp

17 In our laboratory, optogenetic stimulation after trauma exposure was suffic

18 del thus offers a theoretical account of how optogenetic stimulation alters the excitability of corti

19 Using a combination of optogenetic stimulation and 2-photon imaging in mice, we

20 We therefore combined cerebellar optogenetic stimulation and CA1 calcium imaging with an

21 E STATEMENT A new technique for simultaneous optogenetic stimulation and calcium imaging across wide

22 avioural assays, volumetric calcium imaging, optogenetic stimulation and circuit modelling to reveal

23 Here, we combined electrical or optogenetic stimulation and fast-scan cyclic voltammetry

24 Using optogenetic stimulation and in vivo two-photon imaging i

25 By combining optogenetic stimulation and intracellular recordings in

26 ibitory input fields measured with patterned optogenetic stimulation and intracellular recordings rev

27 ictable chronic mild stress and repeated ACC optogenetic stimulation and is reversed by fluoxetine.

28 Optogenetic stimulation and recording of these GABA neur

29 This was obtained through optogenetic stimulation and subsequent confocal imaging

30 Our system exploits the interplay between optogenetic stimulation and time lapse fast impedance as

31 Optogenetic stimulation and visual stimuli are used to s

32 By combining optogenetic stimulation and voltammetry, we address this

33 using optical imaging of intrinsic signals, optogenetic stimulation, and multi-unit recording.

34 hronic multielectrode recording, closed-loop optogenetic stimulation, and pharmacology to show that r

35 iode (LED)-based fluorescence microscopy and optogenetic stimulation as well as a Peltier-based tempe

36 response to sleep deprivation, whereas tonic optogenetic stimulation at a rate similar to baseline ac

37 We show that targeted optogenetic stimulation based on analysis of AT morpholo

38 We show that targeted optogenetic stimulation based on automated, non-invasive

39 Population dynamics emerging after optogenetic stimulation both correctly predicted behavio

40 locked the dopamine release induced by local optogenetic stimulation but only partially antagonized d

41 gation of spontaneously occurring ripples by optogenetic stimulation, but not randomly induced ripple

42 Both in vivo neuropharmacology and optogenetic stimulation can be used to decode neural cir

43 tonic currents, and that both electrical and optogenetic stimulation can evoke NMDA-mediated synaptic

44 cortex in unrestrained mice, demonstrate its optogenetic stimulation capabilities to examine cerebell

45 s synchronization by delivering out-of-phase optogenetic stimulation caused mice to perseverate on ou

46 Optogenetic stimulation combined with axonal tracing ind

47 Here, we show that repetitive optogenetic stimulation confined to cholinergic axons is

48 Finally, optogenetic stimulation confirmed the functional role of

49 ptors to their axon terminals in the EB, and optogenetic stimulation coupled with electrophysiologica

50 Surprisingly, we find the effects of optogenetic stimulation depend primarily on distance and

51 Optogenetic stimulation designed to saturate LTD produce

52 s study, we develop an implantable multisite optogenetic stimulation device (MOSD) based on shape-mem

53 sequence of impaired motor function, because optogenetic stimulation did not alter motor performance.

54 These results demonstrate that optogenetic stimulation driven coherent neuronal dynamic

55 ition controls spike timing, suggesting that optogenetic-stimulation-driven coherence may arise from

56 g and experiments to study the mechanisms of optogenetic-stimulation-driven coherent neuronal dynamic

57 However, the mechanisms by which optogenetic stimulation drives coherent dynamics remain

58 Long-term in vivo recordings, optogenetic stimulation, drug perturbation and analysis

59 Our results demonstrate that optogenetic stimulation during neural differentiation ca

60 fire immediately before slow waves and their optogenetic stimulation during ON periods of NREM sleep

61 ynaptic to specific populations targeted for optogenetic stimulation, giving rise to all-optical func

62 y, artificial disruption of iMSN output with optogenetic stimulation heightened avoidance of open are

63 ltaneous patch-clamp recordings and targeted optogenetic stimulation in acute mouse hippocampal slice

64 Optogenetic stimulation in awake head-fixed mice consist

65 Using single or dual optogenetic stimulation in brain slices from male and fe

66 istry, whole-cell patch-clamp recordings and optogenetic stimulation in hippocampal slices obtained f

67 ion-making tasks [9-13], previous studies of optogenetic stimulation in primates have not demonstrate

68 wever, seizure probability was higher during optogenetic stimulation in PV-ChR2 compared to PV-Cre an

69 Optogenetic stimulation in the caudate-putamen and neoco

70 ted basal forebrain regions upon MgRA-driven optogenetic stimulation in the lateral hypothalamus.

71 ne how coherent neuronal dynamics arise from optogenetic stimulation in the primate brain.

72 issue by using extracellular recordings and optogenetic stimulations in mice across postnatal develo

73 The wireless optogenetics stimulation in the subcutaneous adipose tis

74 Optogenetic stimulation, in contrast, initiated and main

75 r ablation of the raphe reduces sleep, while optogenetic stimulation increases sleep.

76 In vivo optogenetic stimulation induced a synchronized down-stat

77 Interestingly, burst optogenetic stimulation induces wakefulness in accordanc

78 Importantly, we also show that LDT-VTA optogenetic stimulation is reinforcing, and that iuGC an

79 his spatiotemporal dynamic using closed-loop optogenetic stimulation is sufficient to increase moveme

80 An optogenetic stimulation mimicking this LC-CA1 activity i

81 s from layer V pyramidal neurons showed that optogenetic stimulation normalized cortical hyperexcitab

82 Remarkably, repeated M2-DLS optogenetic stimulation normalized motor behavior in HD

83 Optogenetic stimulation of 5-HT input to the VTA combine

84 for the anxiolytic effect observed following optogenetic stimulation of 5-HT inputs into the dBNST.

85 on, Lee et al. (2014) show that subthreshold optogenetic stimulation of a brainstem locomotion area c

86 t spindle density is markedly reduced by (i) optogenetic stimulation of a major GABA/PV inhibitory in

87 Here, we show that selective optogenetic stimulation of a molecularly defined subset

88 Here we replaced the odor CS with optogenetic stimulation of a specific olfactory glomerul

89 Further, within the PVN, selective optogenetic stimulation of afferents that arise from the

90 e resolve this paradox by showing that brief optogenetic stimulation of AgRP neurons before food avai

91 Despite these observations, optogenetic stimulation of AgRP neurons reliably produce

92 Furthermore, we find that constant optogenetic stimulation of anesthetized cat area 21a pro

93 to the hypothalamic paraventricular nucleus; optogenetic stimulation of ARC TH axons inhibited parave

94 Optogenetic stimulation of ARC TH cells inhibited pro-op

95 ly, working memory deficits were restored by optogenetic stimulation of astrocytes with melanopsin.

96 ing an animal to associate a foot shock with optogenetic stimulation of auditory inputs targeting the

97 Responses to self-generated optogenetic stimulation of auditory thalamocortical term

98 ts by increasing germline proliferation, and optogenetic stimulation of AWB neurons is sufficient to

99 Moreover, optogenetic stimulation of axon collaterals of double-pr

100 Optogenetic stimulation of axons in the BLA arising from

101 Similarly, optogenetic stimulation of Bar(Vglut2) neurons triggers

102 Constant, low wattage optogenetic stimulation of basal forebrain (BF) neurons

103 ing cholinergic levels in the cortex through optogenetic stimulation of basal forebrain cholinergic n

104 us, the wake-promoting effect of "selective" optogenetic stimulation of BF cholinergic neurons could

105 Prior evidence indicates that optogenetic stimulation of BLA projections to the medial

106 d by C3 neurons is less than that induced by optogenetic stimulation of C1 neurons; however, combined

107 Here we demonstrate in rats that optogenetic stimulation of C3 neurons induces sympathoex

108 Specifically, we used 1 Hz optogenetic stimulation of calcium/calmodulin-dependent

109 Optogenetic stimulation of CANE-captured social-fear neu

110 Optogenetic stimulation of cardiac cycles with in-animal

111 express ChR2 solely in Tac2 neurons, in vivo optogenetic stimulation of CeA Tac2-expressing neurons d

112 It involves optogenetic stimulation of cells stably transfected to e

113 Dentate hyperactivity was abolished by optogenetic stimulation of cholinergic fibers.

114 , we now provide physiological evidence that optogenetic stimulation of cholinergic interneurons trig

115 Using optogenetic stimulation of cholinergic neurons in ChAT-C

116 Furthermore, optogenetic stimulation of ChR2 expressing DRGs induces

117 cits a flavor aversive effect, and selective optogenetic stimulation of ChR2-expressing SF1 projectio

118 A single short-lasting (30-300 milliseconds) optogenetic stimulation of CN neuron activity abruptly s

119 Here we show that optogenetic stimulation of cortical glutamatergic affere

120 assembly and display calcium activity after optogenetic stimulation of cortical neurons.

121 Therefore, we hypothesized that optogenetic stimulation of cortical projections would re

122 Unilateral optogenetic stimulation of cortical pyramidal neurons bo

123 Glutamate uncaging or optogenetic stimulation of cortical spheroids triggers r

124 We investigated the effects of optogenetic stimulation of D1+ (direct) and A2A+ (indire

125 gonists also suppressed DA release evoked by optogenetic stimulation of DA axons.

126 Optogenetic stimulation of different projection targets

127 pecific olfactory glomerulus and the US with optogenetic stimulation of distinct inputs into the vent

128 Electrical and optogenetic stimulation of dopamine terminals evoked rob

129 ts of choice behavior, we employed selective optogenetic stimulation of dopamine terminals in the NAc

130 Conversely, optogenetic stimulation of dopamine-excitable cells in d

131 We found that optogenetic stimulation of DRN 5-HT neurons enhanced dow

132 However, combining optogenetic stimulation of DRN 5-HT neurons with a low d

133 Optogenetic stimulation of DRN Pet-1 neurons reinforces

134 Although optogenetic stimulation of either cell type significantl

135 We used optogenetic stimulation of either glutamatergic or choli

136 is specific to vHIP afferents to the NAc, as optogenetic stimulation of either mPFC or AMY afferents

137 Furthermore, song performance-contingent optogenetic stimulation of either VTA afferent was suffi

138 tion channels that have been widely used for optogenetic stimulation of electrically excitable cells.

139 Optogenetic stimulation of fear acquisition neurons incr

140 Consistent with these results, we found that optogenetic stimulation of GABAergic interneurons in the

141 aventricular hypothalamic nucleus (PVH), and optogenetic stimulation of GABAergic LH --> PVH fibers i

142 drives voracious water consumption, and that optogenetic stimulation of GABAergic neurons in the same

143 Optogenetic stimulation of GAD65(+) TBCs increased chord

144 Optogenetic stimulation of GAD65(+) TBCs on the anterior

145 onditions to assess the behavioral impact of optogenetic stimulation of GAD65(+) TBCs.

146 the first definitive evidence that selective optogenetic stimulation of glial-like GAD65(+) TBCs evok

147 Pathway-specific, optogenetic stimulation of glutamatergic LHA-LHb circuit

148 In mice, we show that optogenetic stimulation of glutamatergic neurons in MnPO

149 Responses to optogenetic stimulation of glutamatergic premotor neuron

150 tions of SNr neurons, which we confirm using optogenetic stimulation of GPe terminals within the SNr.

151 Moreover, optogenetic stimulation of graft-derived axons extending

152 Optogenetic stimulation of host corticospinal tract axon

153 sults demonstrate that ketamine infusions or optogenetic stimulation of IL-PFC are sufficient to prod

154 n vivo reversal of this pathophysiology with optogenetic stimulation of infralimbic cortex-accumbens

155 her, our findings indicate that the targeted optogenetic stimulation of intracellular Ca(2+) signal a

156 Electrical or optogenetic stimulation of lateral hypothalamic (LH) GAB

157 ne neuron activity and food seeking, whereas optogenetic stimulation of left vagus nerve neurons sign

158 oduced a real-time place preference, whereas optogenetic stimulation of LHA-LHb glutamatergic fibers

159 Optogenetic stimulation of LN-innervating sensory fibers

160 Optogenetic stimulation of M1 afferents produced the opp

161 Optogenetic stimulation of MeApv using a synaptic depres

162 We found that 20-Hz optogenetic stimulation of MFC axon terminals increased

163 e show, using sniff-triggered, dynamic, 2-D, optogenetic stimulation of mitral/tufted cells, that vir

164 Consistently, optogenetic stimulation of MnR neurons suppressed ripple

165 Optogenetic stimulation of mouse ARC TH neurons increase

166 Using patterned optogenetic stimulation of mouse hippocampal CA3 neurons

167 We find that optogenetic stimulation of mouse zona incerta (ZI) gamma

168 We previously found that optogenetic stimulation of mPFC neurons in susceptible m

169 Chemogenetic or optogenetic stimulation of mPFC->pPVT neurons in adultho

170 inhibited EPSCs evoked at -70 mV in vitro by optogenetic stimulation of mPFC-NAcore terminals in alco

171 Intersectional optogenetic stimulation of MPOA neurons that express ESR

172 Furthermore, optogenetic stimulation of mPOA(Nts)-VTA circuitry promo

173 of actomyosin network topology in vivo using optogenetic stimulation of myosin-II in Drosophila embry

174 Optogenetic stimulation of NAc cell bodies induced a pos

175 Reality (PiVR) system to conduct closed-loop optogenetic stimulation of neural functions in unrestrai

176 Optogenetic stimulation of neurons in the left or right

177 -aspartate microinjection in the SNpc and/or optogenetic stimulation of nigro-vagal terminals in the

178 forated patch-clamp recording, we found that optogenetic stimulation of nigrostriatal dopamine axons

179 We also demonstrate that chemogenetic or optogenetic stimulation of npvf-expressing neurons induc

180 To explore this directly, we paired optogenetic stimulation of OH cells (at rates that promo

181 y, and latency) using holographic two-photon optogenetic stimulation of olfactory bulb neurons with c

182 Finally, selective optogenetic stimulation of olfactory cortical projection

183 al that both the application of oxytocin and optogenetic stimulation of oxytocinergic terminals suffi

184 Optogenetic stimulation of P2ry1 neurons acutely silence

185 cked endogenous oscillatory activity through optogenetic stimulation of parvalbumin-expressing intern

186 ated chloride channel abolishes pumping, and optogenetic stimulation of pharyngeal muscle in these an

187 We show that the optogenetic stimulation of Pitx2(ON) neurons drives thre

188 Indeed, optogenetic stimulation of PPN axons reliably evoked spi

189 In this study, we show that in vivo optogenetic stimulation of prelimbic (PrL) and infralimb

190 Optogenetic stimulation of projections from these neuron

191 eptor-mediated IPSCs evoked by electrical or optogenetic stimulation of Purkinje cells were more than

192 arkinson's disease, where cell type-specific optogenetic stimulation of PV(+) neurons over other neur

193 tent with their central role in NVC, in vivo optogenetic stimulation of pyramidal cells evoked COX-2-

194 IL-17 deficiency can be bypassed by optogenetic stimulation of RMG.

195 Optogenetic stimulation of RTN with channelrhodopsin-2,

196 Furthermore, optogenetic stimulation of S1 in expert mice was suffici

197 Critically, in vivo optogenetic stimulation of S1-corticostriatal afferents

198 Optogenetic stimulation of S1-corticostriatal afferents

199 adults rescued the transport defects, while optogenetic stimulation of select synapses revealed CaMK

200 Serotonin release elicited by direct optogenetic stimulation of serotonergic neurons activate

201 Optogenetic stimulation of serotonin neurons in the dors

202 Furthermore, optogenetic stimulation of SGNs restored auditory activi

203 Optogenetic stimulation of single neurons of either clas

204 Finally, closed-loop optogenetic stimulation of SOM, but not PV, terminated s

205 lectrical stimulation of dmPFC layer I or by optogenetic stimulation of specific interneurons ex vivo

206 l neurons in combination with mechanical and optogenetic stimulation of specific mechanoreceptor type

207 Optogenetic stimulation of spiral ganglion neurons (SGNs

208 ized step function opsin (SSFO) in the mPFC; optogenetic stimulation of SSFO at mPFC-to-NAc projectio

209 Intra-NAc optogenetic stimulation of SSFO selectively at mPFC-to-N

210 Our results show that optogenetic stimulation of Sst-GABA neurons results in a

211 Direct optogenetic stimulation of STN neurons was effective in

212 at/vglut2) neurons produces minimal wake and optogenetic stimulation of SuM(vgat/vglut2) terminals el

213 Local optogenetic stimulation of sympathetic inputs induces a

214 motility patterns produced by electrical and optogenetic stimulation of sympathetic pathways.

215 Furthermore, optogenetic stimulation of terminals modulated time-rela

216 pproach, our results indicate that selective optogenetic stimulation of TH(VTA) neurons enhanced cere

217 ns of the facial vibrissae and electrical or optogenetic stimulation of thalamic neurons that project

218 Finally, delta-frequency optogenetic stimulation of thalamic synaptic terminals o

219 in the cortex in response to repeated brief optogenetic stimulation of thalamocortical afferents.

220 We evaluated the reinforcing properties of optogenetic stimulation of thalamostriatal terminals, wh

221 Furthermore, optogenetic stimulation of the ACC was sufficient to ind

222 tching and prevented induction of hunting by optogenetic stimulation of the anterior-ventral tectum.

223 rvate distinct sets of subnuclei, and strong optogenetic stimulation of the axon terminals induces di

224 Postspatial training optogenetic stimulation of the BLA-mEC pathway altered t

225 In vitro optogenetic stimulation of the claustrum induced excitat

226 ivo and disrupted locomotor activation after optogenetic stimulation of the direct pathway.

227 Similarly, optogenetic stimulation of the DMS-GPe iMSNs reduced eth

228 Random optogenetic stimulation of the DOG thermosensory neurons

229 We combined optogenetic stimulation of the dorsal raphe nucleus (DRN

230 We also found that optogenetic stimulation of the IL-PFC produced rapid and

231 Here, we find that optogenetic stimulation of the MLR in awake, head-fixed

232 In this work, we use optogenetic stimulation of the premotor cortex in awake,

233 e dendritic spines of single V1 neurons with optogenetic stimulation of the presynaptic neural popula

234 aventricular thalamus (PVT), selective chemo/optogenetic stimulation of the PVT-projecting SF1 neuron

235 We first demonstrated that optogenetic stimulation of the STN excited its major pro

236 and evoked responses to either electrical or optogenetic stimulation of the subfornical organ.

237 ed locomotion could be reversed in adults by optogenetic stimulation of the touch receptor (mechanose

238 reduced aggression-seeking behavior, whereas optogenetic stimulation of the VMHvl accelerated moment-

239 e and are functionally connected to Bar, and optogenetic stimulation of these axon terminals reliably

240 Furthermore, optogenetic stimulation of these GABAergic projections f

241 We found that optogenetic stimulation of these neurons enabled learnin

242 ion promotes both wakefulness and REM sleep, optogenetic stimulation of these neurons in sleep select

243 Functionally, optogenetic stimulation of these neurons promotes the ac

244 Next, we studied how optogenetic stimulation of these projections affects beh

245 g reward with fear extinction training or by optogenetic stimulation of this circuit during fear exti

246 Optogenetic stimulation of this circuit has net excitato

247 Optogenetic stimulation of this liver-projecting melanoc

248 We also demonstrate that optogenetic stimulation of this population of TRP-expres

249 We find that optogenetic stimulation of TRN neurons and their axons e

250 Optogenetic stimulation of tVTA neurons inhibited VTA DA

251 e activated during theta network activity or optogenetic stimulation of ventral CA1 pyramidal cell ax

252 Optogenetic stimulation of VMHvl in male mice evokes att

253 th that of a reference stimulus (sucralose + optogenetic stimulation of VTA dopamine neurons) and fou

254 We report that optogenetic stimulation of VTA glutamate neurons or term

255 , we show in mouse brain slices that a brief optogenetic stimulation of VTA-to-NAc projection induced

256 pressed on glutamatergic neurons in the PFC, optogenetic stimulation of which elicited activation of

257 Optogenetic stimulation of wM1 evokes rhythmic whisker p

258 Optogenetic stimulation of wS1 drove activity in wM1 wit

259 Finally, chemogenetic or optogenetic stimulations of LH MCH neural activity incre

260 osing the loop optogenetically (i.e., basing optogenetic stimulation on simultaneously observed dynam

261 Optogenetic stimulation or inhibition of bursty subicula

262 that endogenous NPY, released in response to optogenetic stimulation or synaptically evoked spiking o

263 Here, we investigated how optogenetic stimulation (OS) of SCs regulates their deve

264 A novel, low power, waxing-and-waning optogenetic stimulation paradigm preferentially induced

265 ity to manic behaviors, we developed a novel optogenetic stimulation paradigm that produces a sustain

266 colliculus (SC), was established via a novel optogenetic stimulation paradigm.

267 Cortical electrical and local optogenetic stimulation produced significant increases i

268 esponses and memory formation, whereas their optogenetic stimulation produces defensive responses and

269 Optogenetic stimulation promises to provide new ways to

270 We report that optogenetic stimulation raises firing rates uniformly ac

271 utamatergic antagonists and circuit specific optogenetic stimulation revealed that behavioral respons

272 re not responsible for this increased drive; optogenetic stimulation revealed that lateral orbitofron

273 Interestingly though, animals that received optogenetic stimulation showed significantly improved fe

274 ns have a strong influence on the effects of optogenetic stimulation.SIGNIFICANCE STATEMENT Whether S

275 ther these effects could be recapitulated if optogenetic stimulation specifically targeted 5-HT termi

276 Previous optogenetic stimulation studies have confirmed that rein

277 t was ipsilateral, but not contralateral, to optogenetic stimulation, suggesting involvement of inter

278 After local optogenetic stimulation, SWA and cortical synchrony decr

279 However, this effect was not observed when optogenetic stimulation targeted 5-HT terminals in the N

280 Constant optogenetic stimulation targeting both pyramidal cells a

281 gularity were independently controlled using optogenetic stimulation, the eye movements elicited were

282 Upon optogenetic stimulation, the fly's behavior changes dram

283 tested this hypothesis using electrical and optogenetic stimulation to determine if brain slices cou

284 glutamatergic terminals (lower frequency of optogenetic stimulation to induce glutamate release).

285 functional effect of such networks, we used optogenetic stimulation to trigger antidromic spikes in

286 ists even under the artificial conditions of optogenetic stimulation, underscoring the canonical natu

287 Optogenetic stimulation using cre recombinase-dependent

288 The reduction in MTC firing during optogenetic stimulation was confirmed in recordings in a

289 rtex as a Wilson-Cowan neural field in which optogenetic stimulation was represented by an external c

290 Using optogenetic stimulation, we demonstrate that this suppre

291 Using optogenetic stimulation, we determined that these neuron

292 Using optogenetic stimulation, we show that GLP-1 excites medi

293 Electrical and optogenetic stimulations were used to analyze amygdala-d

294 These observations, based on optogenetic stimulation, were confirmed by direct anatom

295 locally transformed into a type II medium by optogenetic stimulation which predominantly targets inhi

296 effects of STN DBS using cell type-specific optogenetic stimulation with a much faster opsin, Chrono

297 Here, we demonstrate a simple method for optogenetic stimulation with body side-, body segment-,

298 implant produces sufficient light power for optogenetic stimulation with minimal tissue heating (<1

299 at pairing central nucleus of amygdala (CeA) optogenetic stimulation with one option for earning intr

300 The consequences of optogenetic stimulation would optimally be recorded by n