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2 Thus, evolution has fashioned macrophages to orchestrate a coordinated inflammatory and hypoxic gene
3 endothelial cell-derived angiocrine signals orchestrate a favorable immune milieu to facilitate meta
4 to transcription-blocking DNA damage, cells orchestrate a multi-pronged reaction, involving transcri
5 a UTI, whereas monocyte-derived macrophages orchestrate a strong, but ineffective, inflammatory resp
6 binds beta-galactoside glycan structures to orchestrate a variety of important biological events, in
7 analyses, we demonstrated that the enhancer orchestrates a balance between pro- and anti-fate circui
8 efects in the endoplasmic reticulum (ER) and orchestrates a complex program of adaptive cellular remo
9 e that signaling via IL-36 receptor (IL-36R) orchestrates a crucial innate-adaptive immune link to co
11 ic neurotransmission plays a crucial role in orchestrating a multitude of brain functions, including
12 ate that PIFs interact with ABA receptors to orchestrate ABA signaling in darkness by controlling ABI
14 monstrate that p62 (Sqstm1) binds to ATF2 to orchestrate activation of the Ucp1 enhancer and Pgc-1alp
15 environment and activates innate immunity to orchestrate adaptive immunity when synergized with an an
18 t on cardiac myocyte protein phosphorylation orchestrates alterations in the kinase/phosphatase balan
21 find that N260, located in the REC3 domain, orchestrates an extensive network of contacts between RE
22 iated role for tumor cell-derived IL1beta in orchestrating an immune-modulatory program that supports
24 anding of how microbiota-derived metabolites orchestrate and support physiological responses in the h
27 ivity in the supplementary motor area (SMA), orchestrated and sequenced by activity in the dorsal str
28 ping, a persistent question is how the brain orchestrates and integrates the grasp with lift forces o
29 sters are avoided in part as a result of our orchestrated anticipatory efforts to integrate and coord
31 elopment is controlled at multiple levels to orchestrate appropriate choices of cell fate and differe
32 membrane in resting cells that is poised to orchestrate assembly of key signaling components upon re
33 ola virus (EBOV) VP40 matrix protein (eVP40) orchestrates assembly and budding of virions in part by
34 hat subclass-specific cytokine production is orchestrated at the posttranscriptional level through di
36 steoblasts and bone-resorbing osteoclasts to orchestrate balanced progenitor cell recruitment and act
38 ings demonstrate that primary cilia not only orchestrate beta-cell-intrinsic activity but also mediat
43 ave shown that the fetal origin of asthma is orchestrated by a disrupted airway epithelium and furthe
49 ow that a signal from a postsynaptic neuron, orchestrated by endocannabinoids, astrocytic calcium sig
50 nching, BRANCHED 1 (BRC1) coordinates and is orchestrated by endogenous and environmental signals inv
51 iption occurs in a cell type specific manner orchestrated by epigenetic mechanisms including DNA meth
52 onconventional hypersprouting morphology was orchestrated by lymphoma-provided VEGFC and lymphotoxin
53 ic switch from lipid to glucose utilization, orchestrated by modifications in glucose levels and the
54 al for nervous system development, and it is orchestrated by molecular cues that activate receptors o
55 rmation resembles a patterning event that is orchestrated by molecular signaling and the extracellula
58 vergence of ideas and collaborative research orchestrated by Randy Schekman led to the discovery of t
62 espiratory system in people with COVID-19 is orchestrated by specific leukocyte trafficking molecules
63 a feather, micro-regional specificities are orchestrated by temporospatial chromatin looping of the
64 otide excision repair (NER) in eukaryotes is orchestrated by the core form of the general transcripti
66 a process of liquid-liquid phase separation orchestrated by the epigenetic marking and operated by p
68 Asthma-like symptoms in young children are orchestrated by the local airway immune response, but cu
69 ates that initiation of colorectal cancer is orchestrated by the mesenchymal niche and reveals a mech
70 e timing of the root gravitropic response is orchestrated by the reversible inhibition of the TMK1 si
73 processes, such as V(D)J recombination, are orchestrated by the three-dimensional organization of ch
74 emical and transcriptional programs that are orchestrated by the transcription factors MYC and BCL6,
75 ntiation and selection of T cells, a process orchestrated by their interaction with multiple thymic c
77 erentiation involve gene expression programs orchestrated by transcription factors and epigenetic reg
78 melanosome neutralization that is initially orchestrated by transient OCA2 activity to support melan
80 alpha), through phosphorylated S100 residue, orchestrated CAR-HNF4alpha interaction on the CYP2B6 pro
81 -Ser100 RORalpha bridging the PBREM and OARE orchestrates CAR and HNF4alpha to form active chromatin
85 ers of the nuclear receptor (NR) superfamily orchestrate cellular processes that can impact on numero
86 Heat shock transcription factor 1 (HSF1) orchestrates cellular stress protection by activating or
87 ndwork for understanding the role of Pax7 in orchestrating changes in the three-dimensional chromatin
88 vealed thousands of molecular changes and an orchestrated choreography of biological processes involv
90 The metaphase spindle is a dynamic structure orchestrating chromosome segregation during cell divisio
92 obacterium tuberculosis (Mtb) harbors a well-orchestrated Clp (caseinolytic protease) proteolytic mac
93 es, circadian rhythms are also important for orchestrating complex biological processes such as immun
94 we found serine 100-phosphorylated RORalpha orchestrates constitutive androstane receptor (CAR) and
98 r that the Z-ring plays an essential role in orchestrating cytokinesis, precisely what its functions
99 wth speed, and invasion of filopodia by MTs, orchestrating cytoskeletal dynamics toward axonal growth
101 te reptiles, while symmetrical and precisely orchestrated deposition of hard tissue during tooth form
102 n complexes of the innate immune system that orchestrate development of inflammation by activating th
103 ipening of tomato fruit is a complex tightly orchestrated developmental process that involves multipl
104 ectively, our results imply that L. donovani orchestrates different SOCS isoforms to impair macrophag
106 ted enhancers (HICE) act as integration hubs orchestrating differentiation by the formation of three-
107 miR-9/9(*)-124) as reprogramming agents that orchestrate direct conversion of human fibroblasts into
108 roles of the mechanosensory channel Piezo in orchestrating dissemination of Ras(V12)-transformed cell
113 he FG is a few-celled haploid structure that orchestrates division of labor to coordinate successful
117 ve changes in platelet form and function are orchestrated downstream of specific receptors on the pla
118 tion of cell-cycle and self-renewal genes is orchestrated during these conversions remains unclear.
120 nces in our understanding of how nitrogenase orchestrates electron transfer (ET) from the Fe-protein
123 brain-the gene regulatory network (GRN)-that orchestrates expression levels of hundreds to thousands
126 dent Ca(2+) channel activity is dependent on orchestrated fluctuations in the plasma membrane potenti
128 e changes require coordination and are often orchestrated from the CNS, through as of yet poorly unde
129 scription is epigenetically regulated by the orchestrated function of chromatin-binding proteins that
130 cules and postsynaptic transmitter receptors orchestrates functional synaptic specification in a neur
131 R4-NOT complex, which is a master regulator, orchestrating gene expression, RNA deadenylation, and pr
132 ory elements of core pluripotency genes, and orchestrated global changes in chromatin accessibility o
134 infection of a host, Pseudomonas aeruginosa orchestrates global gene expression to adapt to the host
135 circuit mechanisms by which VLM(CA) neurons orchestrate glucoprivation-induced food seeking behavior
136 cular glutamate receptor (VGLUT) 3 machinery orchestrates glutamate release, and its distribution ove
137 ructural dissection of the genetic loci that orchestrates glycosaminoglycan metabolism in the organis
138 of outer mitochondrial membrane 34 (TOMM34) orchestrates heat shock protein 70 (HSP70)/HSP90-mediate
139 nd immune and epithelial cells of the gut to orchestrate host defense in homeostasis and following Sa
140 s, with allosteric elements in each protomer orchestrating host receptor-induced exposure of the co-r
143 G) has been shown to play a critical role in orchestrating immune responses to various pathogens thro
144 se dynamic pathways must therefore be finely orchestrated in order to ensure that the DNA methylation
147 pressed a distinct chemokine axis, which may orchestrate inflammatory myeloid cell recruitment and ex
149 leased by these early-born SST(+) neurons to orchestrate inhibitory circuit formation in the developi
150 e mechanism by which early-born SST(+) cells orchestrate inhibitory circuit formation in the developi
157 ific receptor Notch3 signaling independently orchestrates leukocyte infiltration and organ fibrosis.
159 epatic tissue macrophages are key players in orchestrating liver inflammation, and ER stress can enha
160 s and cellular interactions, ILC3s crucially orchestrate lymphoid organogenesis, promote tissue prote
161 ree key genes that are known to coordinately orchestrate mammary luminal lineage specification and en
163 temperature, or fever, is an important brain-orchestrated mechanism for fighting against infectious o
165 signaling interplay and timing of cues that orchestrate melanocyte lineage progression in the hair f
166 3) is induced in exercising muscle, where it orchestrates metabolic reprogramming that preserves glyc
167 le for the type 2 cytokine interleukin-13 in orchestrating metabolic reprogramming that drives adapta
170 n germinal centers (GCs), complex and highly orchestrated molecular programs must balance proliferati
171 MHC-II restricted CD4(+) T cells control and orchestrated most immune responses, this shortcoming sev
174 circuits exhibit deficits in the ability to orchestrate multiple forms of synaptic plasticity and to
176 uronal circuits that control motor behaviors orchestrate multiple tasks, including inhibition of sens
177 uronal circuits that control motor behaviors orchestrate multiple tasks, including the inhibition of
180 ia are innate immune cells of the brain that orchestrates neurodevelopment, synaptic function, and im
183 nt-derived data showed that the two paralogs orchestrated nonoverlapping transcriptional programs in
184 2 hours of Drosophila development, precisely orchestrated nuclear cleavages, cytoskeletal rearrangeme
185 programme and show how chromosome signalling orchestrates nuclear organisation and meiotic progressio
186 the CCKergic TCs in olfactory processing by orchestrating OB inhibitory activities.SIGNIFICANCE STAT
187 ce of cis-regulatory elements is decoded and orchestrated on the genome scale to determine immune cel
188 fies a core set of transcription factors for orchestrating oocyte growth, and provides an alternative
194 ment to recruit the chromatin factor SMC1 to orchestrate pluripotency-specific intrachromosomal loopi
195 nnervates hundreds of principal neurons, and orchestrates population activity through its powerful an
198 s play a central role in gene expression and orchestrate production, function, and turnover of mRNAs.
203 he disulfide bonds in cbEGF domains uniquely orchestrate protein unfolding by showing that MFS disulf
205 in the hierarchy play to achieve it, through orchestrated reduction of manifolds' radius, dimensional
208 nonenzymatic effects of HYAL2 are crucial in orchestrating RhoA signaling and downstream pathways tha
209 circadian oscillator is a gene network which orchestrates rhythmic expression across the day/night cy
210 t, which helps understanding how plant cells orchestrate root morphogenesis to gene expression with t
211 id core, and oligosaccharide domain together orchestrate saponin adjuvant's potentiation of immune re
212 Our work offers insights into mechanisms orchestrating selective promoter activation in metabolic
213 lity, such as the Val66Met polymorphism, may orchestrate sensitivity to stress, trauma, and risk of s
217 m constitutes a subcellular compartment that orchestrates signal transduction independent from the ce
218 trinsic clock as a sensor of feeding cues to orchestrate skeletal muscle oxidation required for globa
220 is organized into multiple compartments for orchestrating stepwise adult stem cell development and h
222 sident group 2 innate lymphoid cells (ILC2s) orchestrated suppression of natural killer (NK) cell-med
224 into how mitochondrial dynamics and quality orchestrate T cell antitumor responses and commitment to
227 ite myrocin C (1), that featured a carefully orchestrated tandem fragment coupling-annulation cascade
228 ibited properties of a flexible coordinator (orchestrating task changes), while CON acted as a flexib
229 Moreover, our data suggest that islet clocks orchestrate temporal profiles of insulin and glucagon se
230 findings lend insights into mechanisms that orchestrate the (de)acylation that fine-tunes ion channe
232 exes, indicating that its primary role is to orchestrate the assembly of the transport machinery.
233 f functional cross-talk and its potential to orchestrate the cell-wide redistribution of organelles o
235 dentify the regulatory processes required to orchestrate the diel pattern of carbon fluxes within mes
236 ral properties of physiological signals that orchestrate the ejection of milk from alveolar units and
237 of synaptic inhibition, a property that will orchestrate the extent and duration of neuronal excitabi
238 ulate LD biogenesis and lipid homeostasis to orchestrate the formation of the permeability barrier fo
240 To gain access to the N-RNA template and orchestrate the L(RdRP), L(PRNT), and L(MT), an oligomer
242 neurons modulates growth and puberty and may orchestrate the sex differences in endocrine function ob
243 araventricular nucleus of the thalamus (PVT) orchestrates the acquisition and maintenance of opiate-a
244 going forward is to uncover how the rosette orchestrates the behavior of a functional network of con
247 ur data elucidate the mechanism by which Vpx orchestrates the challenging task of nuclear translocati
248 e 10A (PDE10A) activity in the basal ganglia orchestrates the control of coordinated movement in huma
249 ry immunization, the GM-CSF released by AECs orchestrates the cross-talk between cDC2s and CD4(+) T c
252 n factors and cis-regulatory elements (CREs) orchestrates the dynamic and diverse genetic programs th
254 ellular linear strands, we examined how FHF2 orchestrates the interdependency of sodium, calcium, and
255 An overarching molecular mechanism that orchestrates the multitude of factors controlling epider
256 etween ROS and different plant hormones that orchestrates the plant response to abiotic stress and dr
259 ver the unexplored metabolic adaptation that orchestrates the survival and functions of intratumoral
261 reous shell layer, whereas the second module orchestrates the transport of both ions and proteins to
262 es may detect immune complexes through CD16, orchestrating the inflammatory response through intravas
264 n Recognition Complex (ORC) is necessary for orchestrating the initiation process by binding to origi
266 thelial cells sense the microbiome, actively orchestrating the localization of immune cells, to optim
267 ole of a plastidial retrograde metabolite in orchestrating the transduction of a repertoire of signal
268 ch genes and pathways act in cancer cells to orchestrate their evasion of CTLs, and shows that discre
269 d view of how these two presynaptic proteins orchestrate their functions to achieve synaptic transmis
272 e methyltransferases and lysine demethylases orchestrate these events, their role remains elusive in
273 ntrolateral medulla (VLM(CA)) are thought to orchestrate these responses, the circuit and cellular me
278 DNA methylation plays an essential role in orchestrating these learning-induced transcriptional pro
279 mesenchymal cells, acts as a guidance cue to orchestrate this epithelial pathfinding behavior, but ho
285 against homeostatic premature involution and orchestrates thymic regeneration following stress, while
286 IFNgamma and IL-17 responses, and failed to orchestrate tissue repair, resulting in severe graft fib
288 cquired information, but how this process is orchestrated to avoid interference with ongoing cognitio
289 three epigenetic modifiers of chromatin can orchestrate transcriptional decisions and demonstrate th
290 eneration as a process of highly dynamic and orchestrated transcriptomic and chromatin accessibility
291 n the function of multidomain scaffolds that orchestrate transient interactions among multiple signal
292 ubiquitously expressed adaptor proteins that orchestrate transmembrane signaling cascades triggered b
295 uss the vital role of lncRNA surveillance in orchestrating various biological processes, including th
296 ical activation of these pathways evolved to orchestrate vascular development but also drives atheros
297 ese fluctuating auxin response gradients are orchestrated via auxin transport to control lobe formati
298 of great interest because of its ability to orchestrate well-organized motion of self-propelled part
300 the specific role of these Zalpha domains in orchestrating ZBP1 activation and subsequent inflammatio