ライフサイエンスコーパス: organizing center

1 factor, or morphogen, that is secreted by an organizing center .

2 ys in the absence of a dedicated microtubule-organizing center.

3 y recruited around the polarized microtubule-organizing center.

4 omes to distribute away from the microtubule-organizing center.

5 with the trans-Golgi network and microtubule-organizing center.

6 ation of CV membranes around the microtubule-organizing center.

7 go on microtubules away from the microtubule-organizing center.

8 he centrosome, also known as the microtubule-organizing center.

9 transport on microtubules to the microtubule organizing center.

10 obular structure adjacent to the microtubule-organizing center.

11 port that the myddosome is a multifunctional organizing center.

12 from the plasma membrane to the microtubule organizing center.

13 material, is the cell's central microtubule-organizing center.

14 e location of the centrosome meiotic-vegetal organizing center.

15 t the tip of the meristem and the underlying organizing center.

16 adopts the function as cellular microtubule organizing center.

17 f an apical stem cell pool and an underlying organizing center.

18 le pole bodies (SPBs), the yeast microtubule organizing centers.

19 microtubule minus-end detachment from their organizing centers.

20 of multipolar spindles and free microtubule-organizing centers.

21 me organisms, for duplication of microtubule-organizing centers.

22 the duplication of a variety of microtubule organizing centers.

23 d by specialized cellular groups that act as organizing centers.

24 both Mbo1p and Gfh1p localize to microtubule organizing centers.

25 in PAR-2 in regions distant from microtubule organizing centers.

26 modulin-like proteins present in microtubule-organizing centers.

27 Nin localizes to noncentrosomal microtubule-organizing centers.

28 complexes localized at specific microtubule-organizing centers.

29 y of either centrosomes or other microtubule organizing centers.

30 from the cell body and the main microtubule-organizing center?

31 at Golgi outposts serve as local microtubule-organizing centers [8] and secretory stations in dendrit

32 mber of gamma-tubulin-containing microtubule-organizing centers, a phenotype reminiscent of cells ove

33 tor, BRAVO (BRASSINOSTEROIDS AT VASCULAR AND ORGANIZING CENTER), acting as a cell-specific repressor

34 egation that led to acentrosomal microtubule-organizing center (aMTOC) formation and subsequent spind

35 to reside in the centrosome, or microtubule-organizing center, an amembranous organelle that regulat

36 Third, inhibition of microtubule organizing center and centrosome polarization impairs ne

37 We present evidence for a tip organizing center and confirm two of its main components

38 tin ring and polarization of the microtubule-organizing center and cytolytic granules to the center o

39 a recycling compartment near the microtubule organizing center and Golgi apparatus.

40 nstitutes a key component of the microtubule-organizing center and nucleates microtubule assembly.

41 entrosome functions as the major microtubule-organizing center and plays a vital role in guiding chro

42 nockdown of C19ORF5 disrupts the microtubule-organizing center and results in microtubule nucleation

43 ed an aster, which is nucleated by a central organizing center and spans the entire cytoplasm.

44 preading and polarization of the microtubule organizing center and the actin cytoskeleton were ineffi

45 We also establish a link between the tip organizing center and the filament-forming protein FilP.

46 sequently, the relocation of the microtubule organizing center and the Golgi apparatus in the directi

47 bled via active transport at the microtubule-organizing center and thereby initiated the formation of

48 M2 inflammasomes colocalize with microtubule organizing centers and autophagosomes.

49 become competent to function as microtubule-organizing centers and basal bodies.

50 s, they failed to polarize their microtubule organizing centers and perforin-containing granules to t

51 Centrosomes are microtubule-organizing centers and play a dominant role in assembly

52 rm for investigating hRPe and hCPe as neural organizing centers and provide support for the model tha

53 WOX gene products are expressed in stem cell-organizing centers and traffic to adjoining cells to act

54 ccumulation, polarization of the microtubule organizing center, and the convergence of cytolytic gran

55 At the core is the dermal papilla, the organizing center, and the epithelial stem cells that re

56 sosome-related organelles to the microtubule-organizing center, as an early step in the cell biologic

57 n of pM140 to an aggresome-like, microtubule organizing center-associated structure that is known to

58 hat the Caulobacter PopZ scaffold creates an organizing center at the cell pole that actively regulat

59 otubule overlaps associated with microtubule organizing centers at both interphase and mitosis.

60 cleosome packing mechanism creates chromatin organizing centers at the 5' ends of genes where importa

61 ganize a bipolar spindle without microtubule organizing centers at the poles.

62 uppression of activation impacts microtubule organizing center-based cytoskeletal rearrangement and g

63 uited to the cap of CD20 and the microtubule organizing center became polarized toward the cap.

64 accumulated in acentriolar microtubule (MT)-organizing centers but failed to adopt a higher-order st

65 ell-induced reorientation of the microtubule-organizing center, but is required for the subsequent ex

66 e ER is concentrated at the microtubule (MT)-organizing center by dynein and is spread by outward ext

67 to the centrosome (the principal microtubule organizing center) by minus-end-directed transport and t

68 bly occurs in the absence of the microtubule-organizing centers called centrosomes.

69 us end interactions from oppositely oriented organizing centers can provide the force for organelle t

70 calcium and evokes dispersal of microtubule organizing center-clustered WPBs.

71 arin and dextran sulfate showed that pattern organizing centers correspond precisely with WntA, wingl

72 accumulation of 6-PGDase at the microtubule-organizing centers could be blocked by colchicine, sugge

73 8), have been cornerstones in studies of how organizing centers differentially pattern tissues.

74 ntiated myofibers, where it forms ectopic MT organizing centers, disrupts perinuclear MT arrays, redu

75 has important functions at the microtubular organizing center during cell division.

76 ain-hindbrain boundary (MHB) is a well-known organizing center during vertebrate brain development.

77 re that C19ORF5 localizes to the microtubule-organizing centers during microtubule regrowth after noc

78 st cells, lose their function as microtubule organizing centers during neuronal development.

79 Equatorial microtubule organizing center (eMTOC) activity was not affected in c

80 ecruit granzyme B+ granules, the microtubule-organizing center, F-actin, Wiskott-Aldrich syndrome pro

81 ranslocation of the virus to the microtubule-organizing center following endosome penetration.

82 n specificity directly but rather acts as an organizing center for a multitude of specificity interac

83 akens-Bogdanov bifurcation that serves as an organizing center for different types of EAD dynamics.

84 the morphogenetic furrow is a developmental organizing center for patterning and cell proliferation.

85 ose that GPR is a structural component of an organizing center for peptidoglycan and membrane synthes

86 exchange protein (cdb3) serves as a critical organizing center for protein-protein interactions that

87 The APR serves as microtubule-organizing center for the 22 subpellicular microtubules

88 mmetric organisms, the midline is a critical organizing center for the developing central nervous sys

89 This suggests that the cilium serves as an organizing center for the early steps of the signal tran

90 The intercalated disc serves as an organizing center for various cell surface components at

91 sterol and are believed to be highly dynamic organizing centers for receptors and their cognate signa

92 ing studies have revealed that lysosomes are organizing centers for signal transduction.

93 Lipid raft microdomains act as organizing centers for signal transduction.

94 molecules, which suggests that they serve as organizing centers for the activation of NF-kappaB.

95 These sites are organizing centers for triaging substrates to distinct q

96 zation, tubulin multimerization, microtubule organizing center formation, calcium/calmodulin signalin

97 hat, after decapitation, planarians build an organizing center from stem cells at the old midline tha

98 gamma-tubulin complexes to microtubule (MT)-organizing centers from yeast to human cells.

99 rotate in the same direction around a common organizing center) have not been demonstrated and studie

100 Centrosomes are the major microtubule-organizing center in animal cells.

101 ear sites as follows: around the microtubule organizing center in association with the cis-Golgi and

102 tes the size of the WUSCHEL (WUS)-expressing organizing center in inflorescence meristems.

103 The centrosome is the major microtubule organizing center in mammalian cells.

104 V-1) disrupts the centrosome, the primary MT organizing center in many cell types.

105 lusters that colocalize with the microtubule-organizing center in patient cells.

106 endosomes (LEs)/lysosomes to the microtubule-organizing center in response to stress in mouse cells.

107 e spindle pole body (SPB) is the microtubule organizing center in Saccharomyces cerevisiae.

108 keletal filaments radiate from a microtubule organizing center in the cVAC.

109 The roof plate is an organizing center in the dorsal CNS that controls specif

110 ve along microtubules toward the microtubule-organizing center in the minus-end direction.

111 rosome, serves as the major microtubule (MT) organizing center in the yeast cell.

112 centrosomes are major microtubule organizing centers in animal cells, and they comprise a

113 Centrosomes are the main microtubule-organizing centers in animal cells.

114 only a few conserved proteins at microtubule-organizing centers in animals, plants, and flagellate pr

115 Centrosomes are the principal microtubule organizing centers in eukaryotic cells and centrosome du

116 goes retrograde transport to the microtubule-organizing centers in neutrophils from pregnant women.

117 rin is an essential component of microtubule-organizing centers in organisms ranging from algae and y

118 Organizing centers in the developing brain provide an as

119 activity of multiple acentriolar microtubule organizing centers in the oocyte.

120 e positioning of the centrosome (microtubule organizing center) in the leading process in front of th

121 ibutable to loss of signaling from forebrain-organizing centers including Fgf8 from the anterior neur

122 Nucleating from MT-organizing centers, including but by no means limited to

123 ons of distal and proximal stem cells and an organizing center known as the quiescent center.

124 l death response initiated by supramolecular organizing centers known as inflammasomes.

125 he behavior of the fission yeast microtubule-organizing center (known as the spindle pole body or SPB

126 ule arrays without a conspicuous microtubule organizing center like a centrosome.

127 ants lack a structurally defined microtubule-organizing center like the centrosome, organization of t

128 HC complexes, lytic granules and microtubule organizing center localization into synaptic areas are s

129 ranscriptionally silent EPODs as the elusive organizing centers, long proposed to topologically isola

130 spindle assembly checkpoints and chromosomal organizing centers may provide a new way to treat p53-de

131 e assembly checkpoints (SAC) and chromosomal organizing centers may provide a way to treat p53-defici

132 ost rostral cranial vessels and the midbrain organizing center (MOC) which gives rise to the posterio

133 Microtubule-organizing centers move from centrosomes to the nuclear

134 microtubules but focuses to the microtubule organizing center (MTOC) after NK cell activation, when

135 ased DGAT1 expression leading to microtubule-organizing center (MTOC) amplification.

136 ization, and polarization of the microtubule organizing center (MTOC) and cytolytic granules to the N

137 udy, we report that, whereas the microtubule organizing center (MTOC) and cytosolic granules follow t

138 orous vacuole (inclusion) to the microtubule-organizing center (MTOC) and promotes its fusion with ly

139 some." This centrosome acts as a microtubule organizing center (MTOC) and remains stationary, forming

140 t granule concentration near the microtubule-organizing center (MTOC) and subsequent delivery by the

141 movement of vesicles toward the microtubule organizing center (MTOC) and translocation of the MTOC t

142 lytic granule convergence to the microtubule-organizing center (MTOC) as an early, prerequisite step

143 utants do not retain a discrete posterior MT organizing center (MTOC) capable of supporting ectopic p

144 The centrosome acts as the microtubule-organizing center (MTOC) during mitosis in animal cells.

145 FA1 polarization, spreading, and microtubule organizing center (MTOC) formation in NK cells.

146 es significant separation of the microtubule organizing center (MTOC) from the nuclear envelope.

147 triolar material, is the primary microtubule-organizing center (MTOC) in animal cells.

148 The centrosome is the major microtubule organizing center (MTOC) in dividing cells and in many p

149 arization and recruitment of the microtubule organizing center (MTOC) in HIV-1-infected cells.

150 lly located distal from the microtubule (MT)-organizing center (MTOC) in IQGAP1-deficient cells.

151 The nucleus is the main microtubule-organizing center (MTOC) in muscle cells due to the accu

152 The microtubule-organizing center (MTOC) is reoriented between the nucle

153 buted to aberrant release of the microtubule organizing center (MTOC) linker protein, C-NAP1, and the

154 e for CENP-F at the centrosome, the major MT organizing center (MTOC) of the cell.

155 otein, moves cargo away from the microtubule-organizing center (MTOC) on microtubules.

156 h actin reorganization preceding microtubule-organizing center (MTOC) polarization to the synapse.

157 ncluding increased calcium flux, microtubule organizing center (MTOC) polarization, phosphorylation o

158 ll killing in part through its effects on MT organizing center (MTOC) polarization.

159 d the location of the centrosome/microtubule organizing center (MTOC) relative to the cell nucleus an

160 and acetylation of MTs emanating from the MT-organizing center (MTOC) shortly after viral entry and m

161 l complex that contains a unique microtubule-organizing center (MTOC) that organizes the cytoskeleton

162 e (MT) cytoskeleton and a movement of the MT organizing center (MTOC) to a position that is just unde

163 lymphocytes, polarization of the microtubule-organizing center (MTOC) to the immunological synapse en

164 t is required for connecting the microtubule organizing center (MTOC) to the nucleus.

165 al synapse, translocation of the microtubule-organizing center (MTOC) to the synapse, and focused sec

166 , signal the polarization of the microtubule organizing center (MTOC) together with cytolytic granule

167 Polarization of the T cell microtubule-organizing center (MTOC) toward the antigen-presenting c

168 The reorientation of the T cell microtubule-organizing center (MTOC) toward the antigen-presenting c

169 as well as reorientation of the microtubule-organizing center (MTOC) toward the APC.

170 the IS implies relocation of the microtubule organizing center (MTOC) toward the contact zone, which

171 splitting and separation of the microtubule-organizing center (MTOC) well before nuclear envelope br

172 ore, blocked the movement of the microtubule organizing center (MTOC), granzyme B (a component of cyt

173 can function as an acentrosomal microtubule-organizing center (MTOC), nucleating new microtubules at

174 ely constant localization at the microtubule-organizing center (MTOC), Nuf is present at the MTOC onl

175 The centrosome acts as a microtubule organizing center (MTOC), orchestrating microtubules int

176 hr505) co-localized with two key microtubule organizing center (MTOC)-associated proteins, pericentri

177 ls involves reorientation of the microtubule organizing center (MTOC).

178 lgi itself functions as an unconventional MT-organizing center (MTOC).

179 , the initiation of the daughter microtubule organizing center (MTOC).

180 ion of lytic granules toward the microtubule-organizing center (MTOC).

181 sembly takes place near the host microtubule-organizing center (MTOC).

182 e the cell nucleus) known as the microtubule organizing center (MTOC).

183 MTs and inducing the reorientation of the MT organizing center (MTOC).

184 membranes and apparently at the microtubule-organizing center (MTOC).

185 can function as an acentrosomal microtubule-organizing center (MTOC).

186 on by linking the nucleus to the microtubule organizing center (MTOC).

187 on the later polarization of the microtubule-organizing center (MTOC).

188 IL-1beta conversion occur at the microtubule-organizing center (MTOC).

189 EC directional migration and mislocalized MT organizing center (MTOC)/Golgi and myosin IIB cell rear

190 crotubule- (MT) and centrosome- [microtubule organizing center (MTOC)] associated protein that regula

191 Moreover, the microtubule-organizing center (MTOC, or centrosome), which rapidly r

192 A can stimulate the formation of microtubule organizing centers (MTOC) on its own.

193 n Mto1 recruits the gamma-TuC to microtubule-organizing centers (MTOCs) [14, 20-22], and analysis of

194 somes, but more diverse types of microtubule organizing centers (MTOCs) also exist, especially in dif

195 OZART1, Mzt1/Tam4, is located at microtubule-organizing centers (MTOCs) and coimmunoprecipitates with

196 ts gamma-TuCs specifically to cytoplasmic MT organizing centers (MTOCs) and interphase MTs.

197 ortin beta in the coalescence of microtubule organizing centers (MTOCs) and MI spindle assembly are f

198 C becomes active specifically at microtubule-organizing centers (MTOCs) and not more broadly througho

199 In young embryos, hundreds of microtubule-organizing centers (MTOCs) are assembled completely from

200 Microtubule-organizing centers (MTOCs) are large, multi-subunit prot

201 Non-centrosomal microtubule organizing centers (MTOCs) direct microtubule (MT) organ

202 Microtubule-organizing centers (MTOCs) form, anchor, and stabilize t

203 a) family members associate with microtubule-organizing centers (MTOCs) from yeast to humans, but the

204 gamma-tubulin and pericentrin at microtubule-organizing centers (MTOCs) in mouse oocytes arrested at

205 Positioning of microtubule-organizing centers (MTOCs) incorporates biochemical and

206 the spindle that can persist as microtubule organizing centers (MTOCs) into interphase.

207 e mitotic spindle originate from microtubule-organizing centers (MTOCs) located at either pole.

208 Microtubule-organizing centers (MTOCs) nucleate microtubules that ca

209 Centrosomes, the main microtubule organizing centers (MTOCs) of metazoan cells, contain an

210 Regulation of microtubule organizing centers (MTOCs) orchestrates the reorganizati

211 e in microtubule nucleation from microtubule organizing centers (MTOCs) such as the animal centrosome

212 epithelial cells, attachment of microtubule-organizing centers (MTOCs) to intermediate filaments (IF

213 The switch from centrosomal microtubule-organizing centers (MTOCs) to non-centrosomal MTOCs duri

214 larization of lytic granules and microtubule-organizing centers (MTOCs) toward the immune synapse bet

215 embled from randomly distributed microtubule-organizing centers (MTOCs) without centrioles, because o

216 rom noncentrosomal intracellular microtubule organizing centers (MTOCs), although such structures rem

217 representing the most prominent microtubule organizing centers (MTOCs), disappeared during plant evo

218 Microtubule-organizing centers (MTOCs), known as centrosomes in anim

219 etosomes, centrosomes, and other microtubule organizing centers (MTOCs), whether by direct filiation

220 gamma-tubulin complexes to microtubule (MT) organizing centers (MTOCs).

221 core structure of centrosomes or microtubule-organizing centers (MTOCs).

222 Centrosomes are primary microtubule (MT)-organizing centers (MTOCs).

223 he de novo formation of multiple microtubule-organizing centers (MTOCs).

224 ted proteins present at specific microtubule organizing centers (MTOCs).

225 centrin and gamma-tubulin within microtubule organizing centers (MTOCs).

226 gregates were not transported to microtubule organizing centers (MTOCs).

227 ymmetrically dividing cells, the microtubule-organizing centers (MTOCs; mammalian centrosome and yeas

228 rtical anchor for noncentrosomal microtubule organizing centers (ncMTOCs) in the Drosophila oocyte.

229 iption factor produced in cells of the niche/organizing center (OC) of shoot apical meristems.

230 ense network of proteins, is the microtubule-organizing center of animal cells.

231 The centrosome is the microtubule organizing center of human cells and facilitates a myria

232 containing vacuoles close to the microtubule organizing center of infected epithelial cells.

233 The centrosome is the major microtubule-organizing center of most mammalian cells and consists o

234 e spindle pole body (SPB) is the microtubule organizing center of Saccharomyces cerevisiae.

235 which is normally expressed in the stem cell organizing center of shoot meristems.

236 le body (SPB) serves as the sole microtubule-organizing center of the cell, nucleating both cytoplasm

237 The centrosome is the primary microtubule organizing center of the cells and templates the formati

238 nterior neural ridge (ANR), which acts as an organizing center of the forebrain by producing FGF8 mor

239 Centrosomes are the microtubule-organizing centers of animal cells that organize interph

240 number of centrosomes, the major microtubule-organizing centers of animal cells, is critical for the

241 ntrioles represent the principal microtubule organizing centers of animal cells.

242 hat build centrosomes, the major microtubule-organizing centers of animal cells.

243 It is found in microtubule-organizing centers of organisms ranging from algae and y

244 ltaNLS mutant was blocked at the microtubule organizing center or immediately upstream of nuclear por

245 ericentriolar sites close to the microtubule organizing center or in specialized nuclear domains call

246 tructures either adjacent to the microtubule-organizing center or widely distributed in the cytoplasm

247 ation of the two proteins in the microtubule organizing center, our results suggest that centrin is c

248 elle that functions as the major microtubule-organizing center, plays an essential role in the format

249 Surprisingly, microtubule organizing center polarity at the IS, which does not dep

250 thymocyte development as well as microtubule organizing center polarization and cytolytic function in

251 Microtubule organizing center polarization and granule reorientation

252 s range significantly suppressed microtubule organizing center polarization and granzyme B release in

253 e contact site with APC, altered microtubule-organizing center polarization and the IS structure, and

254 le secretion and by showing that microtubule organizing center polarization is dispensable for effici

255 d for conjugate formation, MTOC (microtubule organizing center) polarization, and NKG2D-dependent cel

256 ive CD8(+) T cells polarized the microtubule organizing center, produced IL-2, proliferated, and diff

257 tatic Golgi elements, associated with the MT-organizing center proteins gamma-tubulin and pericentrin

258 aling within and between these two embryonic organizing centers remained intact in FN-null mutants.

259 ase and diacylglycerol-dependent microtubule organizing center reorientation, while depleting the poo

260 Centrosomes are microtubule-organizing centers required for error-free mitosis and e

261 The basal body is a microtubule-organizing center responsible for organizing the cilium,

262 rs of bilateral clusters include the rostral organizing center (ROC) which gives rise to the most ros

263 -strands and two alpha-helices with the zinc organizing center showing remote resemblance to the treb

264 ectious agents and the use of supramolecular organizing centers (SMOCs) as signaling organelles that

265 ic protein complexes known as supramolecular organizing centers (SMOCs).

266 e find no evidence for a canonical stem-cell organizing center subtending these cells.

267 the action of mediators released from nearby organizing centers, such as the floor plate and paraxial

268 al meristem is composed of the quiescent (or organizing) center surrounded by stem (initial) cells fo

269 differentiation by limiting the size of the organizing center that maintains stem cell identity in n

270 he floor plate, an essential ventral midline organizing center that produces the morphogen Shh, has d

271 Centrosomes are key microtubule-organizing centers that contain a pair of centrioles, co

272 Primary cilia are important organizing centers that control diverse cellular process

273 is, we demonstrate the presence of forebrain organizing centers that express secreted growth factors,

274 Centrosomes are microtubule-organizing centers that facilitate bipolar mitotic spind

275 till speculative, lack the major microtubule organizing centers that most cells use to assemble and p

276 Inflammasomes are supramolecular organizing centers that operate to drive interleukin-1 (

277 arallel color stripes mirrored around linear organizing centers that run between the anterior and pos

278 onic organizer and for formation of the head organizing center (the anterior mesendoderm, or AME).

279 Our studies identify a new core organizing center, the assembly zone that controls aECM

280 re organized with plus-ends away from the MT organizing center, the regulation of non-centrosomal MT

281 the importance of centrosomes as microtubule-organizing centers, the mechanism and regulation of PCM

282 s states that centrosomes act as microtubule-organizing centers throughout the cell cycle.

283 as indicated by a failure of the microtubule-organizing center to align with the direction of cell mi

284 t the trans-Golgi network as an alternate MT organizing center to facilitate virus spread.

285 fenestration to enable a single microtubule organizing center to nucleate both cytoplasmic and nucle

286 es emanating from the equatorial microtubule-organizing center to position the nuclei away from the c

287 F5 plays a role in anchoring the microtubule-organizing center to the centrosomes.

288 and induce reorientation of the microtubule-organizing center to the immunologic synapse (IS).

289 mined by the polarization of the microtubule-organizing center to the immunological synapse.

290 A-4 and the reorientation of the microtubule-organizing center to the site of T-cell receptor engagem

291 thin protrusions remote from the microtubule organizing center triggers actomyosin contractility cont

292 cted cells did not begin to lose microtubule-organizing centers until 13 hpi.

293 These observations reveal that microtubule organizing centers use minus to plus-end directed remote

294 PLK1, and gamma-tubulin) to the microtubule-organizing center via the RhoA signaling pathway.

295 unsuccessful polarization of the microtubule-organizing center, which alters the polarity of the rece

296 is determined in most cells by a microtubule-organizing center, which nucleates microtubule assembly

297 resulted from molecular reprogramming of an organizing center whose activity controls outgrowth and

298 showed the formation of multiple microtubule organizing centers with Aurora kinase A and gamma-tubuli

299 EL (WUS) transcription factor establishes an organizing center within the shoot meristem that is esse

300 a model system for understanding microtubule organizing centers, yet very little is known about the m