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1 imensional culture conditions (physiomimetic organotypic culture).
2 eric and submucosal plexuses after 7 days in organotypic culture.
3 Intact otic capsules were maintained in organotypic culture.
4 ture dish than the much more labor-intensive organotypic culture.
5 uced expression of interleukin-1alpha by the organotypic culture.
6 elium is formed by the NIKS keratinocytes in organotypic culture.
7 helial stratification and differentiation in organotypic culture.
8 of the mouse utricle after short periods in organotypic culture.
9 sponses as modeled in three-dimensional (3D) organotypic culture.
10 rized architecture in three dimensional (3D) organotypic culture.
11 at postnatal days (P7-P14) and maintained in organotypic culture.
12 dence for the defective DNA damage repair in organotypic culture.
13 role of oxidative stress was investigated in organotypic cultures.
14 ologous components in chimeric monolayer and organotypic cultures.
15 ted with dominant-negative CaSR in postnatal organotypic cultures.
16 important for binding to p130 in extracts of organotypic cultures.
17 N lesions, condylomata, and HPV16-transduced organotypic cultures.
18 n rat cochlea outer hair cells maintained in organotypic cultures.
19 ulate a normal epidermis, REKs were grown in organotypic cultures.
20 from single basket interneurons in cortical organotypic cultures.
21 n primary visual cortex in vivo and cortical organotypic cultures.
22 were made from SGNs in P0-P5 mouse cochlear organotypic cultures.
23 , brefeldin A was used to block secretion in organotypic cultures.
24 up-regulated following Shh treatment in the organotypic cultures.
25 f II-4 cells was altered by ultraviolet B in organotypic cultures.
26 tion and established novel three-dimensional organotypic cultures.
27 abnormality was not detected in neocortical organotypic cultures.
28 liferation, and apoptosis in HaCaT-ras/bcl-2 organotypic cultures.
29 g ultraviolet irradiation in HaCaT-ras/bcl-2 organotypic cultures.
30 increased expression of GLT-1 in spinal cord organotypic cultures.
31 latory region during the viral life cycle in organotypic cultures.
32 pallidosubthalamic projection was studied in organotypic cultures.
33 aintained in either submerged cultures or in organotypic cultures.
34 ars) were differentiated ex vivo to generate organotypic cultures.
35 ate steroidogenesis and steroid signaling in organotypic cultures.
36 y restricted the number of infected cells in organotypic cultures.
37 erneuron migration in mouse MGE explants and organotypic cultures.
38 rin beta1; and increased cell invasion in 3D organotypic cultures.
39 ammary epithelia in vivo, ex vivo, and in 3D organotypic cultures.
40 h two-colour Ca(2+) and glutamate imaging in organotypic cultures.
41 ld be unlike other herpesviruses examined in organotypic cultures.
42 opment and also upon stimulation in cortical organotypic cultures.
43 drocytes, mixed glial cells, and spinal cord organotypic cultures.
44 ingle epithelial cells and three-dimensional organotypic cultures.
45 alization of beta-catenin in vitro and in 3D organotypic cultures, accompanied by upregulation of WNT
46 tested in three-dimensional tracheospheres, organotypic cultures, air-liquid interface cultures, and
48 ion of M-CSFR on microglia endogenous to the organotypic culture also rescued neurons from excitotoxi
50 ering RNA (siRNA)-mediated knockdown in skin organotypic culture and functional assessment of barrier
52 ally relevant drugs blocked invasion both in organotypic culture and in animals, suggesting a new tre
54 lionic axons based on their disappearance in organotypic culture and on their expression of tyrosine
55 l day 6 cerebellar slices were maintained in organotypic culture and treated with glutamate receptor
57 ECs in rigid and compliant three-dimensional organotypic cultures and 2) restores the induction of th
58 69 pairs in cortex-striatum-substantia nigra organotypic cultures and 538 pairs in acute striatal sli
60 is model for monitoring CMA in live animals, organotypic cultures and cell cultures from these mice,
61 use of biomechanically compliant or rigid 3D organotypic cultures and combined them with global micro
62 were recorded from hair cells in denervated organotypic cultures and in acutely excised epithelia.
63 sualize nests of marked, dysplastic cells in organotypic cultures and in cultures transplanted to nud
66 ion was significantly inhibited in HaCaT-ras organotypic cultures and was associated with high rates
67 A expression, reduced tumor cell invasion in organotypic culture, and restricted tumor growth in vivo
69 orted long-term epidermal regeneration in 3D organotypic cultures, and resulted in the manifestation
70 loss and dendritic regression in hippocampal organotypic cultures, and selective blockade of the CRFR
71 ctors that differed between wild-type and MT organotypic cultures, and then corrected these differenc
72 ian cells lines, as well as mouse cerebellar organotypic cultures, and we also show that they exhibit
74 ion or by growth and maturation in epidermal organotypic culture) as well as a cytokine or bacterial
75 nicotinic activation of alpha7-nAChRs in WT organotypic culture, as well as cell culture, increases
76 differentiation of the epithelium formed in organotypic culture, assessed by basal K19 and suprabasa
79 d an invasive phenotype in three-dimensional organotypic cultures but failed to cause HBECs to form t
80 missive for complete epithelial formation in organotypic culture, but imposes a growth constraint in
81 spase-14) were normally expressed in control organotypic cultures, but were expressed at reduced leve
82 e investigated in nonobese diabetic mice and organotypic cultures by immunohistochemistry, microarray
83 resembles that induced in murine spinal cord organotypic cultures by tumor necrosis factor alpha (TNF
84 analysis procedure for structurally complex organotypic cultures (CALYPSO) applied to fluorescence-b
85 cellular P. gingivalis in both monolayer and organotypic cultures compared to free antibiotic or poly
90 RNA interference studies both in vivo and in organotypic culture demonstrate that the beta2*-nAChRs a
91 el quantitative image analysis tool with 3-D organotypic cultures, demonstrate that stromal changes a
92 induced in primary astrocytes, neurons, and organotypic cultures, demonstrating that this phenomenon
102 and filaggrin/beta-gal of mixtures grown in organotypic cultures for 7 days demonstrated that when i
103 nd rescues gap junction coupling in cochlear organotypic cultures from connexin-deficient mice that a
104 We have developed and characterized two new organotypic cultures from hamster brainstem and lung tis
105 in IPF fibroblasts and collagen secretion in organotypic cultures from IPF patients, thus suggesting
106 commissure can regenerate across a lesion in organotypic cultures from postnatal day (P) 6 gerbils, b
107 In the present study, we further exploit organotypic cultures from wild-type and SOD1(G93A) mice
108 phoproteomic analyses, longitudinal imaging, organotypic cultures, functional assays, animal studies,
110 fected auditory and vestibular hair cells of organotypic cultures generated from the postnatal mouse
112 eurons from cortex-striatum-substantia nigra organotypic cultures grown for 5-6 weeks using somatic w
113 Controlling the microenvironment of such organotypic cultures has impact in tissue engineering, c
115 in authentic functional properties in mature organotypic culture, hippocampal slice cultures were est
117 solated cells of the ICC lineage and gastric organotypic cultures, hyperglycemia stimulated prolifera
118 ange in regenerative capacity can develop in organotypic cultures, IC slices with an intact commissur
119 potential decline and is rescued in cochlear organotypic cultures in low potassium milieu, indicating
120 ardial biopsies were harvested and plated as organotypic cultures in the presence or absence of MSC f
121 agging of endogenous proteins in primary and organotypic cultures in vitro and developing, adult, age
122 , we have generated novel, three-dimensional organotypic cultures in which skin keratinocytes were gr
124 ) cycle intermediates in vivo and in ex vivo organotypic cultures, indicating that suppressed labelli
125 ssion of shh in HaCaT keratinocytes grown in organotypic cultures induced a basal cell phenotype, as
126 ells by either methylcellulose suspension or organotypic culture induces LMP1 expression prior to Z a
127 pically along the margin of the hindbrain in organotypic cultures, inferior olivary axons could pathf
129 These putative progenitors were absent from organotypic cultures lacking mature ICC (Kit(+)CD44(+)CD
131 and knockdown of Scrib in lung explants and organotypic cultures leads to reduced cohesion of lung e
132 We here describe that in stable hippocampal organotypic cultures, LTD also is not a unitary event bu
133 elium exists as a stratified tissue in vivo, organotypic cultures may serve as a better model of EBV
135 that the pattern of GABAergic neurons within organotypic cultures mimicked the expression pattern see
136 e observations illustrate the utility of the organotypic culture model for the investigation of intra
137 al equivalents (HEEs) are a state-of-the-art organotypic culture model in preclinical investigative d
141 ection of S631G variant into a 3-dimensional organotypic culture model of normal esophageal squamous
145 in rat keratinocytes, we created an in vitro organotypic culture model that closely mimics the diseas
146 udy inductive mechanisms, a rat keratinocyte organotypic culture model that faithfully mimics HA meta
147 To accomplish this, we have established an organotypic culture model that mimics a preneoplastic ti
148 re mutant (Kv2.1W365C/Y380T: Kv2.1 DN) in an organotypic culture model to manipulate channel expressi
151 cytes are induced to differentiate in a skin organotypic culture model, both matriptase and prostasin
154 idering the physiological relevance of human organotypic culture models and their utility for high-th
155 have all led to valuable clinical insights, organotypic culture models have emerged as tractable sys
156 including from in vivo imaging and in vitro organotypic culture, now suggests that both programmes c
159 amined the real-time behavior of cells in an organotypic culture of the mammary glandular epithelium.
161 xpression of Kv channels were explored using organotypic cultures of brainstem prepared from P9-P12 r
162 nisms, we used microscopy-based assays on 3D organotypic cultures of Caco-2 cysts as a model system.
167 endogenous soluble factor was NRG1, we used organotypic cultures of E24 MAM-treated ferret neocortex
168 le of Cux-1 in mammalian kidney development, organotypic cultures of embryonic mouse kidney were incu
169 Using a combination of genetic approaches, organotypic cultures of embryonic pancreata, and genomic
171 e, we demonstrate that EBV is able to infect organotypic cultures of epithelial cells to establish a
172 Addition of either FasL or TNF-alpha to organotypic cultures of fetal rat olfactory epithelium r
174 reported that KA-mediated neuronal damage in organotypic cultures of hippocampal slices was associate
176 on and reduce proviral genome integration in organotypic cultures of human cervicovaginal tissue.
177 rmaceutical agents and treatment regimens on organotypic cultures of human disease to expedite drug a
179 gulated cyclin E in epithelial tissues using organotypic cultures of human mammary epithelial cells a
186 d (ii) acinar filling upon three-dimensional organotypic cultures of p130Cas-FL or -CT expressing MEC
187 amplification initiates in spinous cells in organotypic cultures of primary human keratinocytes duri
188 e differentiated cells that reenter S phase, organotypic cultures of primary human keratinocytes tran
191 , we examined the viral infection process in organotypic cultures of primary human keratinocytes.
192 ces of cell-free A beta, and then applied to organotypic cultures of rat brain for varying periods of
196 of this clock-regulated pathway by treating organotypic cultures of SCN with botulinum toxin A or dy
197 rrier in Pelo-deficient mice, we made use of organotypic cultures of skin explants from control and m
198 n the developing human brain by using living organotypic cultures of the human subplate and neighbour
200 n carcinogenesis was assessed using in vitro organotypic cultures of the spontaneously immortalized,
204 l epithelial cells and the application of 3D organotypic culture (OTC), a form of tissue engineering.
206 ough diminished target gene expression in 3D organotypic cultures, particularly in relatively undiffe
208 tro analysis of nigrostriatal development in organotypic cultures prepared from LPS-exposed rat fetus
211 of 2.5 microM TTX for 2 weeks to the SON in organotypic culture produced a 73% decrease in the survi
212 5-positive tumor biopsy specimens (plugs) or organotypic cultures (rafts) consisting of ChHV5-positiv
214 with morpholino antisense oligos in cochlear organotypic cultures revealed a negative correlation bet
215 ns grown in cortex-striatum-substantia nigra organotypic cultures show morphological and electrophysi
217 homogenates and of prion-infected cerebellar organotypic cultured slices and decreased the amount of
219 e of Herpes simplex virus (HSVTK) cerebellar organotypic cultured slices markedly aggravated prion-in
221 cellular mechanisms for elongation using an organotypic culture system as a model of mammary epithel
231 ro models of neurodegeneration such as mouse organotypic culture systems and human organoid models pr
232 liferation, and highlighted the potential of organotypic culture systems for chemogenomic interrogati
234 ed to deposit their own basement membrane in organotypic culture, TGF-beta2 production was reduced.
235 isms, we present a novel breathing brainstem organotypic culture that generates rhythmic neural netwo
236 ting the growth of breast cancer cells in 3D-organotypic cultures that recapitulated pulmonary microe
237 d the effect of ultraviolet B irradiation on organotypic cultures that were fabricated by mixing norm
238 ive protocols for downstream applications of organotypic cultures that will allow users to (i) test t
239 infection are observed in wild-type-infected organotypic cultures, the majority of cells observed in
242 inflammation in mouse primary astrocyte and organotypic cultures, through the AMPK signaling pathway
244 ously reported that exposure of HPV-positive organotypic cultures to benzo[a]pyrene (BaP), a major ca
245 this study, we used isogenic benign mammary organotypic cultures to interrogate the role of mTOR-med
246 6 days) of defined-medium, serum-free spinal organotypic cultures to study intracellular calcium ([Ca
247 either presenilin or APP/APLP2 as well as in organotypic cultures treated with gamma-secretase inhibi
249 ers, retinas from adult mouse were placed in organotypic culture under serum free conditions and allo
250 voltage-sensitive dye changes in hippocampal organotypic cultures undergoing SD were processed via op
252 , FN enhanced outgrowth in three-dimensional organotypic cultures via a mechanism that is dependent u
253 in the rat suprachiasmatic nucleus (SCN) in organotypic culture was studied by in situ hybridization
257 anized knockin (KI) mouse model and in vitro organotypic cultures, we found that reoxygenation or cal
258 emistry in murine cells, tissues, or retinal organotypic cultures, we report that a naphthoquinone/qu
260 p-states in cortex-striatum-substantia nigra organotypic cultures, we show that the delay between up-
263 pression of differentiation markers in these organotypic cultures were analyzed by using immunohistol
265 ine the ligand responsible for this process, organotypic cultures were exposed to untreated HIV, HIV
268 d at the epithelial-mesenchymal interface of organotypic cultures, where a BM-like structure is forme
269 ion into three-dimensional matrix gels or in organotypic culture, whereas re-expression of siRNA-resi
270 d stabilized cysts in three-dimensional (3D) organotypic culture with E-cadherin fragment expression
275 an increased IL1A and treatment of wild-type organotypic cultures with IL1A was sufficient to induce
278 s and immunohistochemistry and correlated in organotypic cultures with the beta(3)-induced progressio