ライフサイエンスコーパス: outer

1 ollagen-positive cells led to a disorganized outer AF (OAF) with thinner, loosened, and disconnected

2 lastids, designated as the translocon at the outer and inner envelope membranes of chloroplast (TOC-T

3 ices consist of a bilayer structure with the outer and inner layers derived from the {111} and {100}

4 rious positions along the nephron and in the outer and inner medulla.

5 -lysosome contact sites was modulated by the outer and inner mitochondrial membrane channels, voltage

6 most evident within the middle region, while outer and inner regions resembled that of control mice.

7 iated mouse kidneys and of dissected cortex, outer, and inner medulla, to represent the corticomedull

8 Customized outer annular PPCMv density in the PXG group with a valu

9 ed using custom Matlab software in inner and outer annuli around the optic nerve region in addition t

10 The inner microcapsule is separated from an outer aqueous compartment stabilized by an outer stimuli

11 sufficient information for the resolution of outer arm structure motifs with recognized biological fu

12 , and tetra-), fucosylation (tri-, core, and outer arm), and galactosylation (di-, tri-, and tetra-)

13 Hair cell counts (both inner and outer) as well as frequency maps of the BM were comparab

14 es in the extracellular site surrounding the outer aspect ofphotoreceptor cells (i.e.,the subretinal

15 fic bacteriocins that translocate across the outer bacterial membrane by a poorly understood mechanis

16 er microplastics than samples from inner and outer bends.

17 assembles into a ring-shaped complex on the outer-bilayer leaflet.

18 al frame-column structure formed between the outer braided yarn and inner axial yarn, the 3DB-TENG is

19 The outer capsid forms a hexagonal lattice (triangulation nu

20 s a previously unknown role for the reovirus outer capsid protein sigma3 in limiting the induction of

21 d by introduction of specific changes to the outer capsid, indicating that an optimal fit between inn

22 ere derived from a different strain than the outer capsid.

23 Several virulence lipids populate the outer cell wall of pathogenic mycobacteria.

24 At the morula stage, outer cells acquire an apical-basal cell polarity, with

25 s achieved by active cell-on-cell migration: outer cells migrate with apical, centripetally polarised

26 An intrinsically disordered region in the outer coat protein, Sec31, drives binding with an inner

27 on mutant, lack the pattern of electrondense outer coat striations, but retain the crust.

28 CotB is an abundant component of the outer coat.

29 n for correction via a standard Reed-Solomon outer code that is interleaved across strands.

30 amine groups to present a positively charged outer corona that attracts negative PFOA molecules.

31 The husk-the leaf-like outer covering of maize ear-has multiple functions, incl

32 proteins localize to the filament inner and outer curvatures to define the supercoiling geometry, ex

33 keratins become asymmetrically inherited by outer daughter cells during cell division, where they st

34 e implants have a 47 mm lumen length, 3.6 mm outer diameter, and 200 mum wall thickness.

35 s misaligned with the orbital planes and the outer disk.

36 While outer distant spiral rainbands produce single-peak meteo

37 vide evidence for the stabilization of these outer domain interactions through glycosylation of key r

38 cal vaccine immunogen eOD-GT8, an engineered outer domain of the HIV-1 glycoprotein-120, on DNA origa

39 2 and flanked by longer alpha-helices at the outer edges, and basic side grooves near the dimer inter

40 Studies have shown that many traits of the outer enamel surface evolve neutrally and can be used to

41 e cutinized and non-cutinized domains of the outer epidermal wall, and affects cell size.

42 eedback within the inner cell walls, not the outer epidermal wall, in guiding organ flattening of org

43 The first domain in the outer, exoplasmic leaf is rich in cholesterol and sphing

44 by end-on attachment of microtubules to the outer face of kinetochores.

45 tion model and features to represent a given outer fold based on features that give the maximum inner

46 We suggest renaming the condition outer foveal microdefect instead of macular microhole, w

47 Outer foveal microdefects were observed in association w

48 From this state (inner gate open and outer gate closed), two additional states are observed,

49 ach involving a unique rotameric flip of the outer-gate residue GLUex.

50 In the outer GC light zones, Tfh cells migrate actively and wit

51 a nervous system is ensheathed by a layer of outer glial cells, the perineurial glia, and a specializ

52 Outer hair cell (OHC) nonlinear capacitance (NLC) repres

53 riginating from acoustic pressure and active outer hair cell force to the inner hair cells that synap

54 Our results suggest that fluid motion due to outer hair cell motility can help maintain longitudinal

55 y cells, including those associated with the outer hair cells (OHCs).

56 the electromechanical properties of cochlear outer hair cells (OHCs).

57 ctive or destructive, which implies that the outer hair cells can either amplify or reduce vibrations

58 ted by a type of sensory receptor cells (the outer hair cells) in response to the acoustic vibrations

59 Tuning in mammals uses somatic motility of outer hair cells, underpinned by the membrane protein pr

60 the aged cochlea, together with some loss of outer hair cells.

61 ss which was more pronounced for North Rona, Outer Hebrides (NR) mothers.

62 ner hydrogel layer to Zn(2+)-ions and/or the outer hydrogel layer to acidic pH or crown ether leads t

63 hat high occupancy of nodes in the inner and outer k-shells and low occupancy in the middle shells of

64 ical cell extrusions, during which extruding outer keratinocytes carry out an entosis-like engulfment

65 be sufficient to recruit the Mis12 and Ndc80 outer kinetochore complexes.

66 ow Cenp-T links centromeric Cenp-ANuc to the outer kinetochore through its HFD and N-terminal Ndc80-b

67 in B1 localises to an expanded region of the outer kinetochore, known as the corona, where it scaffol

68 evealed in situ that bacteria formed a dense outer layer at the liquid-air interface of the liquid dr

69 egions of a hypoxic core and a proliferative outer layer from metabolite distribution.

70 The lipid matrix in the outer layer of mammalian skin, the stratum corneum, has

71 The outer layer of the epidermis composes the skin barrier,

72 plification, with concurrent thinning in the outer layer of the retina.

73 The outer layer, the epidermis, is composed predominantly of

74 erating LiF or forming an extra elastomeric "outer layer," is identified as the more critical determi

75 cariogenic pathogens that were surrounded by outer layers of mixed bacterial communities in juxtaposi

76 ipid plasma membrane, one that describes the outer leaf as consisting of sphingomyelin, phosphatidylc

77 Owing to its outer leaflet binding, Pro12A is much more sensitive to

78 consists of inner leaflet phospholipids and outer leaflet lipopolysaccharides (LPS).

79 ne, a phagocyte recognition marker, from the outer leaflet of senescent RBCs.

80 oyl-sn-glycero-3-phospho-rac-glycerol in the outer leaflet only was quantified by zeta-potential meas

81 red domain formation in the SM+PC-containing outer leaflet relative to ordered domain stability in ch

82 osis, these phospholipids move to the cell's outer leaflet where they are recognized by so-called PS

83 the most abundant phospholipids in the RBCs outer leaflet with PC 34:1 and SM 34:1 being the most ab

84 ular the exclusion of phospholipids from the outer leaflet, is key to creating an almost impenetrable

85 morphology and surface electrostatics of the outer leaflet, the insertion of ACs, in particular their

86 the delivery of exogenous lipids to the cell outer leaflet.

87 rge at the inner leaflet exceeds that at the outer leaflet.

88 l community metabolic models with/without an outer-level (community) objective function.

89 The penetration of outer limiting membrane by photoreceptor nuclei and Mull

90 toxicity assays show good correlation at the outer limits of thiol reactivity but less so for compoun

91 y (0.03-0.77 m/s), exit (0.03-0.53 m/s), and outer loop (0.17-1.13 m/s).

92 irst time, we demonstrate that the CV of the outer loop, rather than isthmus, is the principal determ

93 ns (370-373 mum) and thinnest nasally at the outer macular region (median 256 mum).

94 protein expression of NBCn1 and NBCn2 in the outer medulla (OM) of rat kidney.

95 in the abundance of IRBIT and L-IRBIT in the outer medulla.

96 constituents inhibit HCO(3) transport in the outer medullary collecting duct from the inner stripe (O

97 d on the cytosolic side of the mitochondrial outer membrane (MOM) but does not cross it.

98 e, we demonstrate that various treatments to outer membrane (OM) constituents do not affect the buffe

99 cally anticipated that other members with an outer membrane (OM) might exist in this phylum.

100 The outer membrane (OM) of gram-negative bacteria confers in

101 The asymmetric outer membrane (OM) of Gram-negative bacteria functions

102 The outer membrane (OM) of Gram-negative bacteria is a selec

103 The outer membrane (OM) of Gram-negative bacteria is an asym

104 C16 fatty acid (palmitate) to lipid A by the outer membrane acyltransferase enzyme PagP occurs in imm

105 function of the P and L rings is to seal the outer membrane after motor disassembly.

106 ir complex cell envelope, which comprises an outer membrane and an inner membrane, are an important a

107 iciously chosen surfactant permeabilized the outer membrane and enhanced this effect.

108 t in the permeability barrier imposed by the outer membrane and offers a pathogen-associated molecula

109 s driven by phospholipid accumulation in the outer membrane and regulated by the phospholipid transpo

110 tem is required for translocation across the outer membrane and that a cysteine-rich region directs T

111 protein TraH(N) was found to localize to the outer membrane and the presence of significant amounts o

112 barrel outer membrane proteins (OMPs) to the outer membrane are mediated by the beta-barrel assembly

113 ng expression of essential genes involved in outer membrane biogenesis can also trigger T6SS activati

114 between distinct structural features of the outer membrane cap (OMC) and periplasmic ring (PR).

115 teracts on the surface of live cells with an outer membrane component of the efflux pump, TolC, stimu

116 s include multi-gene phase variation (PV) of outer membrane components, multi-allele PV of restrictio

117 We conclude that outer membrane constriction is coordinated with cell div

118 Coordination of outer membrane constriction with septation is critical t

119 -2 proteins oligomerize at the mitochondrial outer membrane during MOMP, inducing pore formation.

120 n implicated in phospholipid trafficking and outer membrane integrity, and includes an ABC transporte

121 longate successfully, and display no loss of outer membrane integrity.

122 cherichia coli by reducing levels of LPS and outer membrane integrity.

123 Permeabilization of the mitochondrial outer membrane is a key step in the intrinsic apoptosis

124 The outer membrane is a key virulence determinant of gram-ne

125 ycocerosate (PDIM), one of the most abundant outer membrane lipids, plays important roles in both def

126 In the outer membrane of Enterobacteriaceae, trimeric porins co

127 The highly asymmetric outer membrane of Gram-negative bacteria functions in th

128 Lipopolysaccharide (LPS) resides in the outer membrane of Gram-negative bacteria where it is res

129 Lipopolysaccharide (LPS), a component of the outer membrane of gram-negative bacteria, disrupts the a

130 ere, we show that the major component of the outer membrane of gram-negative bacteria, lipopolysaccha

131 In the outer membrane of gram-negative bacteria, O-antigen segm

132 Mitochondrial outer membrane permeabilization (MOMP) is a core event i

133 BCL-2) protein family regulate mitochondrial outer membrane permeabilization (MOMP), a phenomenon in

134 sis induces cell death through mitochondrial outer membrane permeabilization (MOMP), which is conside

135 mitochondrial DNA depletion or mitochondrial outer membrane permeabilization blockage via BCL2 overex

136 ive, our findings suggest that mitochondrial outer membrane permeabilization may represent a valid ta

137 hanisms: (i) beta-lactamase inhibitors; (ii) outer membrane permeabilizers; (iii) efflux pump inhibit

138 We conclude that outer membrane perturbation can be sensed by P. aerugino

139 itochondria, and chloroplasts all possess an outer membrane populated with a host of beta-barrel oute

140 cerevisiae IgA or IgG, anti-Escherichiacoli outer membrane porin C, anti-CBir1, anti-flagellin 2, an

141 ed lipopolysaccharide (LPS) and depletion of outer membrane porin OmpT, which confers resistance to h

142 e bacteria only by passive diffusion through outer membrane porins.

143 riplasmic chaperone SurA plays a key role in outer membrane protein (OMP) biogenesis.

144 bility of a C. trachomatis recombinant major outer membrane protein (rMOMP) vaccine to elicit cross-s

145 phagocytophilum surface protein (Asp14), and outer membrane protein A (OmpA) are essential for optima

146 cal sensory rhodopsin II and the beta-barrel outer membrane protein W have been investigated in lipid

147 Bacterial outer membrane proteins (OMPs) contain a unique "beta ba

148 Integral beta-barrel outer membrane proteins (OMPs) function to establish and

149 ia, the folding and insertion of beta-barrel outer membrane proteins (OMPs) to the outer membrane are

150 eponema phylogroups for putative beta-barrel outer membrane proteins and considered their potential a

151 bacterial pathogen Vibrio cholerae jettisons outer membrane proteins and lipids in vesicles as it ent

152 The Escherichia coli outer membrane receptor FepA transports ferric enterobac

153 nce of significant amounts of TraH(N) in the outer membrane requires TraG(N) .

154 nd retracting to thread this DNA through the outer membrane secretin, PilQ.

155 and osmotic protection to the cell, and the outer membrane serves as a permeability barrier against

156 Gram-negative pathogens are enveloped by an outer membrane that serves as a double-edged sword: On t

157 ative bacteria with proteins tethered to the outer membrane through a lipid anchor.

158 ll as the transport of lipid moieties to the outer membrane to establish membrane rigidity and stabil

159 actant that destabilizes the rigidity of the outer membrane to exert pleiotropic effects on the funct

160 protein TonB to dislodge the plug domains of outer membrane TonB-dependent nutrient transporters.

161 nt membrane distortion and the production of outer membrane vesicle-like features, while NPs bearing

162 Outer membrane vesicles (OMVs) produced by Gram-negative

163 The outer membrane vesicles (OMVs) produced by P. gingivalis

164 displayed increased biogenesis of bacterial outer membrane vesicles (OMVs).

165 is dynamically and selectively packaged into outer membrane vesicles (OMVs).

166 Thus, bacteria use outer membrane vesiculation to exchange cell surface com

167 the localization of an adhesin, LapA, to the outer membrane via a variant of the classical type I sec

168 ctors serve to maintain the integrity of the outer membrane, including DolP (formerly YraP) a protein

169 Together with the employment of an outer membrane, the detection range of the sensor with b

170 charides in the extracellular leaflet of the outer membrane.

171 -anchored ER proteins from the mitochondrial outer membrane.

172 but it is associated with the mitochondrial outer membrane.

173 rocess by forming pores in the mitochondrial outer membrane.

174 f precursors blocking the import pore in the outer membrane.

175 ligomer that permeabilizes the mitochondrial outer membrane.

176 the inner membrane and transport them to the outer membrane.

177 gy-dependent pyocin translocation across the outer membrane.

178 beta-Barrel Assembly Machinery (BAM) in the outer-membrane for insertion and folding.

179 hemical perturbation or by a mutation in the outer-membrane pilus secretin CpaC stimulates early init

180 Of note, an outer-membrane porin (omp)-deficient strain of Escherich

181 embrane populated with a host of beta-barrel outer-membrane proteins (betaOMPs).

182 terminal signaling domain (NTSD) of PupB, an outer-membrane TonB-dependent transducer.

183 inner membrane, they failed to identify any outer-membrane translocon homologs, which raised the que

184 nthases and hydrolases require activation by outer-membrane-anchored lipoproteins.

185 acting protein rings, spanning the inner and outer membranes to form the ~45-50-nm protein complex, h

186 Their ears are elaborate, as they have outer-, middle-, and inner-ear components.

187 ances parkin-dependent ubiquitination of the outer mitochondria membrane protein mitofusin1.

188 The translocase of outer mitochondrial membrane (TOMM) complex is the entry

189 nctional E3 ubiquitin ligase anchored in the outer mitochondrial membrane with its RING finger domain

190 flets of the Golgi complex, peroxisomes, and outer mitochondrial membrane, but only detect very low s

191 protein 1) and its receptor proteins on the outer mitochondrial membrane.

192 A), RNAs, and other signaling enzymes to the outer mitochondrial membrane.

193 NT, a middle three-layer BN nanotube, and an outer MoS(2) nanotube.

194 The gain-of-function mutation N629D at the outer mouth of the selectivity filter (SF) disrupts inac

195 ion networks involving residues from the SF, outer-mouth vestibule, P-helices, and S5-P segments.

196 The host's conversion of MUC2 to the outer mucus layer allows bacteria to degrade the mucin g

197 SINE1, an outer nuclear envelope component of a plant Linker of Nu

198 Assessment of the outer nuclear layer (ONL) morphology showed preserved ON

199 ed with faster inner nuclear layer (INL) and outer nuclear layer (ONL) thinning.

200 layer and increased ectopic synapses in the outer nuclear layer compared to controls.

201 Stratified outer nuclear layer with many Muller cells suggests high

202 1-positive EYS secretory vesicles within the outer nuclear layer, and diminished EYS protein near the

203 We identified S. cerevisiae Mps2 as the outer nuclear membrane protein that connects the LINC co

204 stem leads to the triggered unlocking of the outer, pH-responsive hydrogel layer and to the release o

205 tested direct interactions between inner and outer photoreceptors using selective recovery of activit

206 We find that IRK-GFP localizes to the outer plasma membrane domain in endodermal cells but loc

207 ctroretinography amplitudes, and thinned the outer plexiform and inner nuclear layers of both WT and

208 defined as inner nuclear layer thinning with outer plexiform layer (OPL) disruption.

209 e significantly fewer ribbon synapses in the outer plexiform layer and increased ectopic synapses in

210 ated RIMS2 localization in the human retinal outer plexiform layer, Purkinje cells, and pancreatic is

211 WT mice, hWtEPOR mice had thinner inner and outer plexiform layers and a greater number of amacrine

212 on) and inactivated states (with D4S4 in the outer position).

213 s euvesicatoria effector protein Xanthomonas outer protein N (XopN), a suppressor of early defense si

214 d firm mobile masses were found in the upper outer quadrant with overlying skin induration.

215 ntify an invasive cell population similar to outer radial glia (oRG), a fetal cell type that expands

216 ing the length of terminal cell divisions of outer radial glial (oRG) progenitors, suggesting cellula

217 547 Ma onwards, with full ventilation of the outer ramp by ~542 Ma.

218 Fibrils in the inner and outer regions of the ZP are oriented perpendicular and p

219 tina," "avascular," "choriocapillaris," and "outer retina to choriocapillaris (ORCC)" slabs automatic

220 Horizontal cells (HCs) are neurons of the outer retina, which provide inhibitory feedback onto pho

221 relative contributions of HC subtypes in the outer retina.

222 ome is a rare self-limiting condition of the outer retina.

223 Outer retinal abnormalities persisted on OCT in patients

224 (1) complete retinal pigment epithelium and outer retinal atrophy (cRORA) and (2) hypertransmission

225 These features included components of outer retinal atrophy (e.g., ellipsoid zone disruption),

226 omplete retinal pigment epithelium (RPE) and outer retinal atrophy (e.g., RPE perturbation with assoc

227 sion should be seen in the larger context of outer retinal atrophy, previously suggested as a new for

228 egular cone patterns in AO-OCT and irregular outer retinal bands in SDOCT.

229 fidelity IRD provides a unique insight into outer retinal complex function.

230 mouse lines developed progressive and severe outer retinal degeneration.

231 Outer retinal layers (interdigitation zone and ellipsoid

232 on of subclinical RD or early termination of outer retinal layers in selected cases may be helpful in

233 logic analysis, cone lipofuscin was found in outer retinal layers of 25% of healthy aged eyes.

234 retinal pigment epithelium loss, and loss of outer retinal layers.

235 all molecule activator of PKM2, during acute outer retinal stress.

236 ckness (CFT), inner retinal thickness (IRT), outer retinal thickness (ORT), subfoveal choroidal thick

237 tween the horizontal diameter of the largest outer ring and foveal hypoplasia grades (P < 0.0001).

238 ated from HS patients and more precisely the outer root sheath cells (ORSCs).

239 r coat layer recruits and is organized by an outer scaffolding layer to drive local assembly of a sta

240 s a small protein localized to photoreceptor outer segment (OS) disc membranes.

241 f synthesis in the inner segment (IS) to the outer segment (OS) is critical for photoreceptor functio

242 exhibited minor disruptions of photoreceptor outer segment dimensions without any mislocalization of

243 The outer segment is constantly renewed with new discs added

244 ck of a foveal pit and no cone photoreceptor outer segment lengthening.

245 uch as PRPH2, the PRPH2 binding partner, rod outer segment membrane protein 1 (ROM1), and rhodopsin w

246 ein lost the ability to oligomerize with rod outer segment membrane protein 1 (Rom1), but retained th

247 The light-sensitive outer segment organelle of the vertebrate photoreceptor

248 tachment, and interactions needed for normal outer segment phagocytosis.

249 nt dimensions without any mislocalization of outer segment proteins, whereas photoreceptors of F45L m

250 improvements in Prph2 protein levels and rod outer segment structure, but not functional rescue in ro

251 We showed that, in addition to outer-segment volume, the most important differences bet

252 the formation of rod and cone photoreceptor outer segments (OS).

253 prompted the loss of adjacent photoreceptor outer segments and photoreceptor death, which eventually

254 ssion of the mutant causes shortening of the outer segments and photoreceptor death.

255 segments and cell bodies in the dark to the outer segments in the light.

256 present in the cavefish inner segments, the outer segments of the photoreceptors in cavefish are mis

257 inal parts, photoreceptors (particularly the outer segments) were noticeably tilted with respect to t

258 ther, it localizes to a small region of cone outer segments: the cell membranes surrounding the axone

259 multi-level interfaces (Si/Li(x)Si/inner-SEI/outer-SEI), thus offering novel insights into the impact

260 ed core-shell composite anode, comprising an outer sheath of lithiated liquid metal (Li(x) LM(y) ) an

261 ltiple connected DNA double helices, and the outer shell is composed of regularly arranged standing-u

262 cating that an optimal fit between inner and outer shells maintains capsid function.

263 ergic stimulation, Aifm2 associates with the outer side of the mitochondrial inner membrane.

264 hondrite meteorites, which originated in the outer Solar System where water was more abundant.

265 ly, to selectively emit thermal radiation to outer space and simultaneously maximize solar reflectanc

266 e daytime and harnessing the coldness of the outer space through radiative cooling to produce electri

267 tmospheric transparency window (8-13 mum) to outer space without any energy consumption, has attracte

268 tic activity of naked In(I)(+) ions, with an outer sphere mechanism for the C-N bond formation and a

269 ively charged and strongly electron-donating outer sphere nucleophile, result in the lowest reaction

270 re discussed, including comparisons between "outer sphere" mechanisms and "metal-ligand cooperation"

271 r it capable of binding O(2) through such an outer-sphere electron transfer mechanism represents a pr

272 rbed as easily leachable 8- to 9-coordinated outer-sphere hydrated complexes, dominantly onto kaolini

273 In an alternative outer-sphere process, nucleophilic attack of a metal-pho

274 o Au disk electrodes for the oxidation of an outer-sphere redox couple (ferrocene methanol) and two i

275 Although results show that outer-sphere redox probes are unproductive for particle

276 P and TPA(+/0) make them excellent probes of outer-sphere reorganization energy, lambda(o), as lambda

277 free-energy barriers for lateral mobility of outer-spherically adsorbed Mg(2+).

278 n outer aqueous compartment stabilized by an outer stimuli-responsive hydrogel layer (thickness of ~1

279 edominance of spinal cord lesions nearer the outer subpial surface compared to secondary progressive

280 from the inner central canal CSF pool to the outer subpial surface.

281 ecialized infection structures to breach the outer surface of a host plant.

282 The outer surface of CPs and ILFs is demarcated by a poorly

283 e these limitations is the decoration of the outer surface of gram-negative bacteria with proteins te

284 Lipidated ATG8s anchored to the outer surface of the phagophore serve as scaffolds for b

285 bres equally and spirally distributed on the outer surface of the substrate.

286 h dendritic oligonucleotides attached to the outer surface.

287 and a mechanically and dimensionally stable outer surface.

288 h complement by producing a small arsenal of outer-surface lipoproteins that bind host complement com

289 is integrated into a vacuum system with the outer surfaces of the cell electrodes at atmospheric pre

290 each, with pitch of ~8 nm, on its inner and outer surfaces.

291 Using the Yersinia pestis outer transmembrane beta-barrel Ail as a model, we delin

292 on was the most usual, followed by the lower-outer (type IV).

293 ural motif called the G-box in the centriole outer wall protein Sas4 interacts with a short region in

294 h highly mineralized tissues emerge into the outer world, and it occurs concomitantly with tooth root

295 Presence of PPL was associated with thinner outer zone arteriolar caliber (109.7 +/- 26.5mum vs 123.

296 In the outer zone, eyes with thinnest arteriolar calibers (quar

297 In the outer zone, the percentage of eyes in the thinnest quart

298 measured at an optic disc centered inner and outer zone.

299 than GCs closer to the Purkinje cell layer (outer-zone GCs).

300 tween the paired and single filaments at the outer zones of the transitional hourglass, as well as in