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1 elle via the TOM complex (translocase of the outer mitochondrial membrane).
2 eins use an alternative pathway to cross the outer mitochondrial membrane.
3 osol, BAK is constitutively localized to the outer mitochondrial membrane.
4 and VDAC1 thus reducing permeability of the outer mitochondrial membrane.
5 tial but was absent in mitoplasts lacking an outer mitochondrial membrane.
6 t include the endoplasmic reticulum (ER) and outer mitochondrial membrane.
7 chondria, leading to its accumulation on the outer mitochondrial membrane.
8 ion by increasing Ca(2+) transfer across the outer mitochondrial membrane.
9 that drives the assembly of proteins in the outer mitochondrial membrane.
10 leavage product to the cytosolic face of the outer mitochondrial membrane.
11 ns (DRPs) must bind specific adaptors on the outer mitochondrial membrane.
12 s 1, 2, and 3), pore-forming proteins in the outer mitochondrial membrane.
13 d demonstrate that it is integrated into the outer mitochondrial membrane.
14 tor, Daedalus (Daed), that is located on the outer mitochondrial membrane.
15 to function as a supportive receptor for the outer mitochondrial membrane.
16 forms the protein-translocating pore in the outer mitochondrial membrane.
17 that is involved in the rearrangement of the outer mitochondrial membrane.
18 an integral membrane protein imbedded in the outer mitochondrial membrane.
19 nsmembrane helices anchor the enzymes to the outer mitochondrial membrane.
20 polyQ domains might associate early with the outer mitochondrial membrane.
21 all molecules and ions across the eukaryotic outer mitochondrial membrane.
22 urified mitochondria and associates with the outer mitochondrial membrane.
23 oapoptotic BCL-2 proteins BAX and BAK at the outer mitochondrial membrane.
24 oform enables colocalization with HK1 on the outer mitochondrial membrane.
25 ied 2Fe-2S-containing protein located in the outer mitochondrial membrane.
26 oltage-dependent anion channel (VDAC) of the outer mitochondrial membrane.
27 s a survival protein that is tethered to the outer mitochondrial membrane.
28 that erastin alters the permeability of the outer mitochondrial membrane.
29 toNEET is an integral protein present in the outer mitochondrial membrane.
30 ysiologic exchange of ATP and ADP across the outer mitochondrial membrane.
31 involving Bax's integral insertion into the outer mitochondrial membrane.
32 which assemble into fission complexes on the outer mitochondrial membrane.
33 own to be sufficient for localization to the outer mitochondrial membrane.
34 ltage-dependent anion channel present in the outer mitochondrial membrane.
35 tochondria shows that TARP is located in the outer mitochondrial membrane.
36 promote the timely loss of integrity of the outer mitochondrial membrane.
37 uitylation of subunits of the translocase of outer mitochondrial membrane.
38 atment, suggesting eNOS association with the outer mitochondrial membrane.
39 ated that huntingtin was associated with the outer mitochondrial membrane.
40 recruitment of the large GTPase Dnm1p to the outer mitochondrial membrane.
41 protein 1) and its receptor proteins on the outer mitochondrial membrane.
42 raction of mislocalized TA proteins from the outer mitochondrial membrane.
43 me biosynthesis during erythropoiesis at the outer mitochondrial membrane.
44 A), RNAs, and other signaling enzymes to the outer mitochondrial membrane.
45 l membrane protein or is integrated into the outer mitochondrial membrane.
46 rst identified Fe-S protein of the mammalian outer mitochondrial membrane.
47 tochondria by ubiquitinating proteins on the outer mitochondrial membrane.
48 nstead, Nrf2 was found to associate with the outer mitochondrial membrane.
49 of dozens of proteins on the surface of the outer mitochondrial membrane.
50 eus, and a third population localizes to the outer mitochondrial membrane.
51 ization of immune regulatory proteins on the outer mitochondrial membrane.
52 (VDAC) proteins are major components of the outer mitochondrial membrane.
53 is commitment is the permeabilization of the outer mitochondrial membrane.
54 rs permeability alterations of the inner and outer mitochondrial membranes.
55 forms at contact sites between the inner and outer mitochondrial membranes.
56 age-dependent anion channel 1 (VDAC1) at the outer mitochondrial membranes.
57 he mitochondrial translocase, translocase of outer mitochondrial membrane 22 (Tom22), steroidogenic a
59 ear factor 4, alpha), TOMM34 (translocase of outer mitochondrial membrane 34) and SRC (SRC proto-onco
60 80 kDa complexes with the translocase of the outer mitochondrial membrane 40 (TOM40) import channel a
61 o studies, 449 participants), translocase of outer mitochondrial membrane 40 gene (one study, 723 par
62 e apolipoprotein E (APOE) and translocase of outer mitochondrial membrane 40 homolog (TOMM40) genotyp
63 ovel BMI associations in loci translocase of outer mitochondrial membrane 40 homolog (yeast) - apolip
64 75650, located in TOMM40 (translocase of the outer mitochondrial membrane 40 homolog)--had a genome-w
65 elated protein 6), and TOM40 (translocase of outer mitochondrial membrane 40), for which antisense ex
66 ing system 60-kD subunit, the translocase of outer mitochondrial membrane 40-kD subunit (TOM40), the
67 chondrial Rho (Miro) GTPases localize to the outer mitochondrial membrane and are essential machinery
68 -2 proteins Bax and Bak can permeabilize the outer mitochondrial membrane and commit cells to apoptos
69 l (VDAC) is the most abundant protein in the outer mitochondrial membrane and constitutes the primary
71 EET is a homodimeric protein anchored to the outer mitochondrial membrane and has a C-terminal [2Fe-2
72 , ceramide formation might occur both in the outer mitochondrial membrane and in the mitochondrial ma
73 nal fragment tBid, which translocates to the outer mitochondrial membrane and induces massive cytochr
74 rrier protein that has been recruited to the outer mitochondrial membrane and interacts with the inne
75 that mitochondrial MRP-1 is expressed in the outer mitochondrial membrane and is a client protein of
76 that mitochondrial MRP-1 is expressed in the outer mitochondrial membrane and is a client protein of
77 the flux of metabolites and ions across the outer mitochondrial membrane and is a key player in cell
78 nthesis that is exclusively localized to the outer mitochondrial membrane and is composed of CYB5B, M
79 strate that ABCB6 is uniquely located in the outer mitochondrial membrane and is required for mitocho
80 This is dependent upon MAO anchoring to the outer mitochondrial membrane and shuttling electrons thr
81 t phospholipase A(2) promotes rupture of the outer mitochondrial membrane and spontaneous release of
82 lls, mitofusin 2 (Mfn2), located on both the outer mitochondrial membrane and the ER surface, has bee
83 VDACs) are the most abundant proteins in the outer mitochondrial membrane and the major transport pat
85 cular weight forms, is localized to both the outer mitochondrial membrane and the plasma membrane, an
86 teins are imported by the translocase of the outer mitochondrial membrane and the presequence translo
87 e A (PKA) and other signaling enzymes at the outer mitochondrial membrane and thereby controls mitoch
88 s from the mitochondria by clustering on the outer mitochondrial membrane and thereby permeabilizing
89 totic Bcl-2 protein Bax can permeabilize the outer mitochondrial membrane and therefore commit human
90 as the crucial anti-apoptotic protein in the outer mitochondrial membrane, and additionally as a gate
91 tant for cytosolic Bax to integrate into the outer mitochondrial membrane, and c-Myc is critical for
93 , differential localization to the inner and outer mitochondrial membranes appears to regulate PINK1
94 localized tail-anchored (TA) proteins of the outer mitochondrial membrane are cleared by a newly iden
97 hat suggest that active BAX inserts into the outer mitochondrial membrane as a monomer and then under
99 ndrial CCP activity because Ccp1 crosses the outer mitochondrial membrane as the heme-free protein.
100 -dependent RNA polymerase interacts with the outer mitochondrial membranes as an integral membrane pr
102 stead employs the archaic translocase of the outer mitochondrial membrane (ATOM), a protein that show
104 n of dAKAP1-PKA "signaling islands" from the outer mitochondrial membrane augments progression toward
105 , however the precise mechanism by which the outer mitochondrial membrane becomes permeable to these
107 flets of the Golgi complex, peroxisomes, and outer mitochondrial membrane, but only detect very low s
108 increased the content of cardiolipin in the outer mitochondrial membrane, but the distribution of ot
109 e, we report that Bbeta2 is localized to the outer mitochondrial membrane by a novel mechanism, combi
110 e, demonstrating that it associates with the outer mitochondrial membrane by binding a protein partne
111 can directly induce permeabilization of the outer mitochondrial membrane by forming a inhibitory com
112 n, Drp1 is recruited from the cytosol to the outer mitochondrial membrane by one, or several, integra
114 wild-type cells, where it is detected on the outer mitochondrial membrane by virtue of its sensitivit
115 n of a protein complex that assembles at the outer mitochondrial membrane called the transduceosome.
116 sure of VDAC leads to the opening of another outer mitochondrial membrane channel through which cytoc
118 e show that exclusive delivery of p53 to the outer mitochondrial membrane confers a significant growt
119 sol and its C-terminal TMD inserted into the outer mitochondrial membrane, consistent with a tail-anc
121 ese findings support the hypothesis that the outer mitochondrial membrane contains receptors specific
123 onformational plasticity in ferric rat liver outer mitochondrial membrane cytochrome b5 (rOM b5) and
124 tochondrial permeability transition, whereas outer mitochondrial membrane damage can occur independen
125 injury during endotoxemia and that inner and outer mitochondrial membrane damage occurs through diffe
126 ay participate in lipopolysaccharide-induced outer mitochondrial membrane damage, but further investi
127 ion of Mcl-1L, which localizes mainly to the outer mitochondrial membrane, decreases significantly in
128 ic mutant stably interacts with Mdv1p on the outer mitochondrial membrane, demonstrating that assembl
132 terparts that face the cytosolic side of the outer mitochondrial membrane/endoplasmic reticulum (ER).
133 carnitine palmitoyltransferase-1 (CPT1), an outer mitochondrial membrane enzyme that controls entry
134 ot detectably cleaved and is retained at the outer mitochondrial membrane, even though it interacts w
135 ndria in association with both the inner and outer mitochondrial membranes facing the intermembrane s
136 ay crystal structure of the first identified outer mitochondrial membrane Fe-S protein, mitoNEET.
137 dases (MAO) A and B are approximately 60-kDa outer mitochondrial membrane flavoenzymes catalyzing the
138 M7 as essential for stabilizing PINK1 on the outer mitochondrial membrane following mitochondrial dam
139 d 2 that mediate mitochondrial tethering and outer mitochondrial membrane fusion, were interrupted by
142 nd fusion machinery via interaction with the outer mitochondrial membrane GTPase proteins Miro1 and M
144 sion requires division of both the inner and outer mitochondrial membranes (IMM and OMM, respectively
145 ports cellular mitochondrial proteins to the outer mitochondrial membrane import receptors, and thus
146 s argue in favor of eNOS localization to the outer mitochondrial membrane in endothelial cells and id
147 late the permeability characteristics of the outer mitochondrial membrane in their nonoligomerized st
148 on, both of which are known to reside at the outer mitochondrial membrane, increases the mitochondria
149 s deposited onto the cytoplasmic face of the outer mitochondrial membrane, increasing antigenic acces
150 irus (FHV) RNA replication complexes form on outer mitochondrial membranes inside approximately 50-nm
151 d with respect to their roles in controlling outer mitochondrial membrane integrity and apoptosis.
153 transmembrane protein primarily found in the outer mitochondrial membrane, is evolutionarily conserve
156 mides can form large, stable channels in the outer mitochondrial membrane, leading to the proposal th
157 o and phosphorylation of Sab by p-JNK on the outer mitochondrial membrane leads to SHP1-dependent and
158 Tim23 tightly associates with both inner and outer mitochondrial membrane-like membranes through a hy
160 ational boost by the MDI-Larp complex on the outer mitochondrial membrane might be essential for mtDN
161 t that the specific lipid composition of the outer mitochondrial membrane might be of crucial relevan
163 ssion are mediated by several GTPases in the outer mitochondrial membrane, notably mitofusin-2 (Mfn-2
164 ed and identified endogenous proteins on the outer mitochondrial membrane (OMM) and endoplasmic retic
165 taVD mutants constitutively localized to the outer mitochondrial membrane (OMM) and fragmented mitoch
166 lly into the endoplasmic reticulum (ER), the outer mitochondrial membrane (OMM) and peroxisomes.
167 ontaneous Ca(2+) pacing, Ca(2+) peaks on the outer mitochondrial membrane (OMM) are much greater than
168 active caspase 8 are localized mainly on the outer mitochondrial membrane (OMM) as integral proteins.
169 been studied in their detergent-purified and outer mitochondrial membrane (OMM) bound forms using a s
172 lular lifespan is contingent upon preserving outer mitochondrial membrane (OMM) integrity, as permeab
175 , but not by Bcl-2, implying that changes in outer mitochondrial membrane (OMM) permeability leading
178 ripheral-type benzodiazepine receptor, is an outer mitochondrial membrane (OMM) protein necessary for
180 ax and Bak spontaneously associated with the outer mitochondrial membrane (OMM) through their respect
182 a mitochondrial matrix protein, acts on the outer mitochondrial membrane (OMM) to facilitate the mov
183 show that IkappaBalpha also localises to the outer mitochondrial membrane (OMM) to inhibit apoptosis.
184 roapoptotic BCL-2 proteins converge upon the outer mitochondrial membrane (OMM) to promote mitochondr
185 increasing the flow of cholesterol from the outer mitochondrial membrane (OMM) to the inner membrane
186 nels (VDACs) are predominant proteins of the outer mitochondrial membrane (OMM) where they contribute
187 ansferase 1 (CPT1), which is anchored in the outer mitochondrial membrane (OMM), controls the rate-li
188 chondrion-associated membranes (MAMs) to the outer mitochondrial membrane (OMM), where it robustly in
189 oscopy showed that Tom22 is localized at the outer mitochondrial membrane (OMM), while 3betaHSD2 is l
191 ome system in the regulation and turnover of outer mitochondrial membrane (OMM)-associated proteins.
198 Here, we report that mitoNEET regulates the outer-mitochondrial membrane (OMM) protein voltage-depen
199 Transmembrane beta-barrels of eukaryotic outer mitochondrial membranes (OMMs) are major channels
200 abolism in yeast by re-directing Psd1 to the outer mitochondrial membrane or the endomembrane system
203 robustly induced by PINK1 expression on the outer mitochondrial membrane, Parkin recruitment to mito
205 n vitro models of lipotoxicity, we show that outer mitochondrial membrane permeability is altered and
206 ell death that is not initiated by increased outer mitochondrial membrane permeability or translocati
207 the BH1,2,3 effector protein Bak, leading to outer mitochondrial membrane permeabilization (OMMP) wit
208 SK3-mediated phosphorylation status controls outer mitochondrial membrane permeabilization in hepatos
209 e as Bax coalescence on the mitochondria and outer mitochondrial membrane permeabilization, and it ma
214 of mitochondria prior to engulfment, and the outer mitochondrial membrane protein FUNDC1 interacts wi
215 iazepine receptor (PBR), is a crucial 18-kDa outer mitochondrial membrane protein involved in numerou
216 likely by influencing protein levels of the outer mitochondrial membrane protein Miro that anchors m
217 nt of kinesin-1 to mitochondria involves the outer mitochondrial membrane protein mitochondrial Rho G
220 pioglitazone led to the discovery of a novel outer mitochondrial membrane protein of unknown function
225 gosomes and is sufficient to deliver another outer mitochondrial membrane protein, Fis1, to autophago
226 ong form of B-cell lymphoma-x (Bcl-x(L)), an outer mitochondrial membrane protein, has been proposed
227 Here we show that VAPB interacts with the outer mitochondrial membrane protein, protein tyrosine p
228 we utilized a cell-permeable peptide of the outer mitochondrial membrane protein, Sab (SH3BP5), as a
235 hich is, in turn, known to interact with the outer mitochondrial membrane proteins Miro1/2, linking m
237 ligase activity is required to ubiquitinate outer mitochondrial membrane proteins, allowing optineur
238 olarized mitochondria where it ubiquitinates outer mitochondrial membrane proteins, initiating lysoso
239 o not regulate PTP activity through TSPO, 3) outer mitochondrial membrane regulation of PTP activity
240 /killer (Bak) undergo oligomerization in the outer mitochondrial membrane resulting in the release of
241 A damage-induced p53/Bcl2 interaction at the outer mitochondrial membrane results in a Bcl2 conformat
242 f these and other signaling molecules to the outer mitochondrial membrane results in the rapid induct
243 otein A recruits FHV RNA specifically to the outer mitochondrial membrane sites of RNA replication co
244 copy imaging method to observe the inner and outer mitochondrial membrane structures and selectively
248 2-associated X apoptosis regulator (BAX), an outer mitochondrial membrane-targeting pro-apoptotic pro
249 mbles into large multimeric complexes on the outer mitochondrial membrane that are visualized as punc
250 ndent proteins take another route across the outer mitochondrial membrane that involves Tom40 in a fo
251 e formation of a multivalent scaffold in the outer mitochondrial membrane that mediates the effect of
252 A and B (MAO-A and MAO-B) are enzymes of the outer mitochondrial membrane that metabolize biogenic am
253 dase A (MAO-A) is an important enzyme on the outer mitochondrial membrane that participates in the ce
254 een Bcl2 and c-Myc in the nucleus and on the outer mitochondrial membrane that significantly enhances
255 el 1 (VDAC-1) is an important protein of the outer mitochondrial membrane that transports energy meta
256 ppress tumor formation by permeabilizing the outer mitochondrial membrane, thereby releasing pro-apop
257 ne protein that forms an aqueous pore in the outer mitochondrial membrane, through which metabolites
258 AKAP1 recruits protein kinase A (PKA) to the outer mitochondrial membrane to phospho-inhibit DRP1.
259 eroidogenesis by moving cholesterol from the outer mitochondrial membrane to the inner mitochondrial
260 litates the movement of cholesterol from the outer mitochondrial membrane to the inner mitochondrial
262 Self-interacting BAX proteins permeabilize outer mitochondrial membranes to trigger apoptotic cell
264 a central component of the translocon of the outer mitochondrial membrane (TOM) complex, is essential
266 rmore, Tim29 contacts the Translocase of the Outer Mitochondrial Membrane, TOM complex, enabling a me
268 ing the interaction of MAM proteins with the outer mitochondrial membrane translocase, Tom22, to acti
269 ropose that 3betaHSD2 associates with IMM or outer mitochondrial membrane translocases facing the int
270 omolecular signaling complex composed of the outer mitochondrial membrane translocator protein (TSPO)
273 annels: voltage-dependent anion channel from outer mitochondrial membrane VDAC, bacterial porin OmpC
274 K II) that is overexpressed and bound to the outer mitochondrial membrane via the porin-like protein
276 ix, and formation of vesicles and tubules of outer mitochondrial membrane, was also observed in both
278 ependent monooxygenase and is located in the outer mitochondrial membrane where it converts l-kynuren
279 -Ras off of the plasma membrane and onto the outer mitochondrial membrane where it induces cell death
280 punctate structures that are targeted to the outer mitochondrial membrane where they mediate mitochon
281 ia an N-terminal transmembrane domain to the outer mitochondrial membrane, where FHV RNA replication
282 cumulates as a 63-kD full-length form on the outer mitochondrial membrane, where it can recruit Parki
283 mic BAX is activated and translocates to the outer mitochondrial membrane, where it forms an oligomer
285 Mammalian Bcl-x(L) protein localizes to the outer mitochondrial membrane, where it inhibits apoptosi
286 ine phosphoprotein (FAST) is tethered to the outer mitochondrial membrane, where it interacts with BC
287 l MRP-1 is glycosylated and localized to the outer mitochondrial membrane, where it is coexpressed wi
288 rved eukaryotic AAA+ ATPase localized to the outer mitochondrial membrane, where it is thought to ext
289 nserved, ubiquitous protein localized in the outer mitochondrial membrane, where it is thought to pla
290 T-treated BL-3 cells revealed lesions in the outer mitochondrial membrane, which are larger than prev
291 ized by the rapid accumulation of BIM on the outer mitochondrial membrane, which could be functionall
292 monstrate that its apoptotic activity at the outer mitochondrial membrane, which involves conformatio
293 we showed that internalized LKT binds to the outer mitochondrial membrane, which results in the relea
294 rgeting induced ceramide accumulation on the outer mitochondrial membrane, which then directly bound
295 ia demonstrated that ABCB6 is present in the outer mitochondrial membrane, while back-titration assay
296 ed inside a 30- to 90-nm invagination of the outer mitochondrial membrane, whose necked aperture to t
297 nctional E3 ubiquitin ligase anchored in the outer mitochondrial membrane with its RING finger domain
298 ng in dissociation of hexokinase II from the outer mitochondrial membrane with subsequent mitochondri
299 modimeric iron-sulfur protein located in the outer mitochondrial membrane with unknown function, but
300 state, MondoA:Mlx complexes localize to the outer mitochondrial membrane, yet shuttle between the mi