ライフサイエンスコーパス: outer root sheath

1 ctedly restricted to the dermal papillae and outer root sheath.

2 ocated in the bulge, a specialization of the outer root sheath.

3 f1, and increased proliferative cells in the outer root sheath.

4 root sheath, and the innermost layers of the outer root sheath.

5 r, proliferate, and appear to migrate up the outer root sheath.

6 t, bulb matrix cells, and basal layer of the outer root sheath.

7 vity was detected in the bulge region of the outer root sheath.

8 xpressed by a subset of keratinocytes in the outer root sheath.

9 the inner root sheath, and the third for the outer root sheath.

10 ow that the nestin-expressing cells form the outer-root sheath.

11 bulge are indeed progenitors of the follicle outer-root sheath.

12 sebaceous glands, hair shafts and inner and outer root sheaths.

13 a tractor mechanism involving the inner and outer root sheaths.

14 o the matrix, sebaceous gland, and inner and outer root sheaths.

15 lso exhibited increased proliferation in the outer root sheath, accelerated hair cycle, reduction of

16 Aldh1a2 expression was seen primarily in the outer root sheath and basal/spinous layer during all sta

17 3 was expressed throughout all layers of the outer root sheath and cyst wall.

18 t at high levels in a subset of cells in the outer root sheath and in precursor cells of the hair sha

19 -stripped hair showed separation between the outer root sheath and inner root sheath of the hair foll

20 detected in the differentiating cells of the outer root sheath and medulla of the follicle during the

21 ckouts, which showed defects in the follicle outer-root sheath and the hair growth cycle, respectivel

22 present in the epidermal layer of the skin, outer root sheath, and hair matrix.

23 al basal cell layer and of the hair follicle outer root sheath, and ~50% reduction of cell numbers in

24 is is where stem cells for the hair follicle outer-root sheath are thought to be located.

25 FP-expressing cells are located in the upper outer-root sheath as well as in the bulge area but not i

26 of normal human epidermis and the inner and outer root sheaths but not the matrix of the hair follic

27 xpression by follicular keratinocytes of the outer root sheath, but not by dermal papilla cells.

28 nective tissue sheath, and EHF for the bulge outer root sheath, by in situ hybridization.

29 ated from HS patients and more precisely the outer root sheath cells (ORSCs).

30 Here, we hypothesized that hair follicle outer root sheath cells act as transducers of mechanical

31 in anagen follicles; and the single layer of outer root sheath cells directly abutting the club hair

32 h reveals a spiral-like downward movement of outer root sheath cells entering the lower bulb region.

33 ser capture microdissection, bulge cells and outer root sheath cells from other follicle regions were

34 K6(+) cells arise from Lgr5-expressing lower outer root sheath cells in anagen, our studies indicate

35 hair bulb cells were depleted, the surviving outer root sheath cells rapidly acquired an SC-like stat

36 arations in vitro, we were able to show that outer root sheath cells release ATP and the neurotransmi

37 combined with pharmacology in a coculture of outer root sheath cells with sensory neurons, we found t

38 rmal differentiation program is activated in outer root sheath cells.

39 colocalize in the hair follicle bulge cells, outer-root sheath cells, and basal cells of the sebaceou

40 model, where a pulling force induced by the outer root sheath contributes to hair fiber extrusion.

41 confirmed that c-Myc immunoreactivity in the outer root sheath correlates with the putative hair foll

42 was limited to the postmitotic cells of the outer root sheath directly abutting the club hair.

43 tner keratin 6 in the companion layer of the outer root sheath during anagen and in the club hair she

44 Melanocytes located in the outer root sheath express Bcl-2 and are TUNEL-negative.

45 ast to hair shaft precursor cells, postnatal outer root sheath expressed TCF3, but not TOPGAL.

46 including the hair shaft, and the inner and outer root sheaths in skin reconstitution assays.

47 gland and in the basal layer of the central outer root sheath including the bulge region.

48 that epithelial compartmentalization of the outer root sheath is more complex than interfollicular e

49 t K15+ cells, but not in supra/proximal bulb outer root sheath K15+ progenitors.

50 complex and multiple subpopulations of basal outer root sheath keratinocytes are described.

51 ably derived from pigment-carrying migrating outer root sheath keratinocytes from the proximal hair f

52 in basal cell carcinoma islands relative to outer root sheath keratinocytes is not simply a reflecti

53 Transgenic overexpression of VEGF in outer root sheath keratinocytes of hair follicles strong

54 pper epidermis and, more prominently, in the outer root sheath keratinocytes of hair follicles.

55 Strong Gli1 immunostaining was seen in the outer root sheath keratinocytes of some hair follicles,

56 d ornithine decarboxylase (ODC) transgene in outer root sheath keratinocytes of the hair follicle wer

57 of foreskin keratinocytes, atopic dermatitis outer root sheath keratinocytes, and H4R-transfected HaC

58 mice that expressed high levels of TSP-1 in outer root sheath keratinocytes, associated with reduced

59 inence in the dermal papilla and in selected outer root sheath keratinocytes.

60 ed H4R mRNA on foreskin keratinocytes and on outer root sheath keratinocytes; H4R mRNA was more abund

61 Therefore, activation is the process whereby outer root sheath melanocytes acquire all of the structu

62 H-1 and alpha-PEP-8 antibodies revealed that outer root sheath melanocytes cannot be identified by an

63 We believe that the inactive outer root sheath melanocytes contain some of the early

64 The majority of the outer root sheath melanocytes were found in the mid to t

65 Overexpression of Dvl2 in the outer root sheath mimics the short-hair phenotype produc

66 ecrease in FGF13 localization throughout the outer root sheath of affected hair follicles.

67 sed in the interfollicular epidermis and the outer root sheath of hair follicles in normal skin as we

68 in the basal layer of the epidermis and the outer root sheath of hair follicles under the regulation

69 f keratin genes known to be expressed in the outer root sheath of hair follicles.

70 ells of cornea and epidermis, as well as the outer root sheath of hair follicles.

71 in basal cells of squamous epithelia and the outer root sheath of hair follicles.

72 of adult mice, where it is restricted to the outer root sheath of hair follicles.

73 son, K14 expression was found throughout the outer root sheath of hair follicles; however, when both

74 sion of K15 was also observed throughout the outer root sheath of the follicles.

75 ential microflora is harboured by the distal outer root sheath of the hair follicle and the hair cana

76 idermis, sebaceous glands, sweat glands, and outer root sheath of the hair follicle with weaker expre

77 prabasal layers of the epidermis, the distal outer root sheath of the hair follicle, and the piloseba

78 to the basal layer of the epidermis and the outer root sheath of the hair follicle, as well as other

79 iating keratinocytes of the epidermis in the outer root sheath of the hair follicle, in myoepithelial

80 found on the scalp and are derived from the outer root sheath of the hair follicle.

81 t directs constitutive ODC expression in the outer root sheath of the hair follicle.

82 ssed in the basal layer of the epidermis and outer root sheath of the hair follicle.

83 lieved that DOPA-negative melanocytes in the outer root sheath of the human hair follicle are activat

84 accentuated in keratinocytes comprising the outer root sheath of the murine hair follicle (HF).

85 olving the interfollicular epidermis and the outer root sheaths of 1 or more hair follicles down to t

86 The ND-GFP stem cells give rise to the outer-root sheath of the hair follicle as well as an ND-

87 repopulated by melanocytes arising from the outer root sheath or follicular papilla of early/mid-cat

88 he present study, hair follicle germinative, outer root sheath or skin basal epidermal cells were sep

89 These findings reveal how the outer root sheath (ORS) and inner hair follicle layers c

90 ut off, and promote features of the follicle outer root sheath (ORS) and multipotent stem cells (bulg

91 e expression was observed exclusively in the outer root sheath (ORS) cells.

92 Histochemistry reports the outer root sheath (ORS) contains high levels of glycogen

93 ive expression in the innermost layer of the outer root sheath (ORS) of hair follicles and inducible

94 the basal keratinocytes of the epidermis and outer root sheath (ORS) of the hair follicle.

95 ure hair its expression is restricted to the outer root sheath (ORS), matrix cells and to the stem ce

96 ng hair follicles, specifically cells of the outer root sheath (ORS), were extensively infected by M-

97 abasal cells of the telogen bulge and anagen outer root sheath (ORS).

98 In addition, as HF-SC numbers dwindle, outer root sheath production is not sustained, and HF do

99 Deletion of CCN2 in dermal papillae and the outer root sheath results in a shortened telogen-phase l

100 r-binding protein-alpha was expressed in the outer root sheath, sebaceous gland, and dermal papilla,

101 and -delta, and Gadd153 were observed in the outer root sheath, sebaceous gland, dermal papilla, and

102 ental and anatomical parallels with follicle outer root sheath, the epithelial component that contain

103 ng, nuclear PS2 staining was observed in the outer root sheath throughout the anagen growth phase.

104 bility of keratinocytes to migrate along the outer root sheath to receive hair inductive stimuli.

105 ss human Bcl-2 in basal epidermis and in the outer root sheath under the control of the human keratin

106 nt accompanied by increased apoptosis in the outer root sheath was significantly accelerated in downl

107 h (IRS), whereas the dermal papilla (DP) and outer root sheath were consistently hr mRNA-negative.

108 ubclass of cells expresses whn, while in the outer root sheath, whn promoter activity is induced as t