ライフサイエンスコーパス: ovarian follicle

1 granulosa cell compartment of the mammalian ovarian follicle.

2 ractions with somatic granulosa cells of the ovarian follicle.

3 triggered by luteinizing hormone (LH) in the ovarian follicle.

4 on of TAFII105 in the granulosa cells of the ovarian follicle.

5 by which a mature oocyte is released from an ovarian follicle.

6 ch changes rapidly with luteinization of the ovarian follicle.

7 oocytes during their development within the ovarian follicle.

8 red by its own multi-cellular structure, the ovarian follicle.

9 e relies on the protected environment of the ovarian follicle.

10 ell-to-cell communication network within the ovarian follicle.

11 eceptors in the mural granulosa cells of the ovarian follicle.

12 al from the surrounding somatic cells in the ovarian follicle.

13 a genome-scale metabolic model of the mouse ovarian follicle.

14 , and evolutionary conservation of mammalian ovarian follicles.

15 he assembly, preservation, and maturation of ovarian follicles.

16 cells and their projections in mouse antral ovarian follicles.

17 genes are expressed in developing mammalian ovarian follicles.

18 t human gene required for the maintenance of ovarian follicles.

19 in adult females AMH is produced by growing ovarian follicles.

20 genic female revealed eGFP expression in her ovarian follicles.

21 study the hormonal regulation of atresia in ovarian follicles.

22 s associated with major increases of cAMP in ovarian follicles.

23 at fail to break down, leading to polyovular ovarian follicles.

24 ation with developmentally late preovulatory ovarian follicles.

25 nts and 11.8% of prepubertal patients showed ovarian follicles.

26 nergy and building blocks for the developing ovarian follicles.

27 synthesized by the granulosa cells (GCs) of ovarian follicles.

28 rimordial germ cells, meiotic germ cells and ovarian follicles.

29 ween printed layers, affects the survival of ovarian follicles.

30 d serum estrogen and higher numbers of large ovarian follicles.

31 th the interpretation of these structures as ovarian follicles.

32 usive expression of R-spondin2 in oocytes of ovarian follicles.

33 lcyclohexene diepoxide (VCD, n=8) to deplete ovarian follicles.

34 s, short-term in vitro activation of dormant ovarian follicles after stimulation of the PI3K-Akt path

35 between the somatic cells and oocyte of the ovarian follicle and is crucial for the regulation of me

36 quired to maintain meiotic arrest within the ovarian follicle and suggests that the follicle may keep

37 enotypes, including the overgrowth of excess ovarian follicles and anovulation.

38 N-cadherin expression was evaluated in ovarian follicles and corpora lutea utilizing immunohist

39 gonadotropins exhibit normal distribution of ovarian follicles and corpora lutea.

40 Ovarian follicles and endometrium thickness less than or

41 n (M105I mutation) causes early depletion of ovarian follicles and female subfertility.

42 ing effector Yes-associated protein (YAP) in ovarian follicles and follicle growth.

43 r the development of Drosophila melanogaster ovarian follicles and NE morphology of myonuclei.

44 llerian hormone (AMH) is produced by growing ovarian follicles and provides a diagnostic measure of r

45 cles have demonstrated a high sensitivity of ovarian follicles and spermatogenic cells to HZE particl

46 and coordinate the development of mammalian ovarian follicles and that the rate of follicular develo

47 ceptors are required for the early growth of ovarian follicles and that they exert this function by p

48 The growth of oocytes within ovarian follicles and their development to mature eggs h

49 ongly expressed by granulosa cells in normal ovarian follicles, and by ovarian dysgerminomas and gran

50 els primarily in ova cytoplasm of developing ovarian follicles, and in the nucleus of spermatogonia a

51 oocyte death, early depletion of functional ovarian follicles, and secondary infertility.

52 pellucida in the functional and degenerative ovarian follicles, and the ovaries remained histological

53 In the ovarian follicle, anti-Mullerian hormone (Amh) mRNA is e

54 Cocaine-induced ovarian follicle apoptosis and adult lethality appear to

55 Oocytes within ovarian follicles are transcriptionally active, producin

56 erial grafts for transplantation of isolated ovarian follicles as a means to preserve fertility.

57 bursa of Fabricius and comparatively low in ovarian follicles at all stages of development.

58 ties abrogated LH-induced steroidogenesis in ovarian follicles but not MA-10 cells, suggesting that L

59 In conclusion, obesity disturbs the equine ovarian follicle by promoting lipid accumulation and alt

60 and triggers the rupture of the preovulatory ovarian follicle by stimulating proteolysis and apoptosi

61 ion of luteinizing hormone (LH) on the mouse ovarian follicle causes meiotic resumption by inhibiting

62 H) in the outer granulosa cells of mammalian ovarian follicles causes meiosis to resume in the oocyte

63 cytokinesis failure, accumulate in Myb-null ovarian follicle cell and wing disc epithelia.

64 drive Sd-mediated cell proliferation in the ovarian follicle cell epithelium in response to mechanic

65 In the Drosophila ovarian follicle cell epithelium, apical membranes are s

66 DPP and EGF signals set the boundary for an ovarian follicle cell fate.

67 ATD, and enzymatic and manual removal of the ovarian follicle cell layers significantly increased spo

68 protein is initially expressed uniformly in ovarian follicle cell nuclei, and is subsequently downre

69 By studying Drosophila ovarian follicle cell progenitors, we identified lysine-

70 Furthermore, by measuring polyploid 16C ovarian follicle cell underreplication we estimated the

71 fly Drosophila melanogaster, where polyploid ovarian follicle cells amplify genomic regions containin

72 s of chorion (eggshell) proteins, Drosophila ovarian follicle cells amplify the chromosomal loci cont

73 f membrane skeletal components in Drosophila ovarian follicle cells and in somatic clones of mutant c

74 The fates of two small subgroups of the ovarian follicle cells appear to be linked: mutations in

75 velopmental gene amplification in Drosophila ovarian follicle cells as a model to investigate how chr

76 phological analyses of the roles of Notch in ovarian follicle cells during Drosophila oogenesis.

77 al for viability, although it is required in ovarian follicle cells for normal eggshell development.

78 lification at the chorion loci in Drosophila ovarian follicle cells is a model for the developmental

79 two clusters of chorion genes in Drosophila ovarian follicle cells is essential for rapid eggshell b

80 Gene clusters amplified in the ovarian follicle cells of Drosophila serve as powerful m

81 patterning by regulating pipe expression in ovarian follicle cells, before its previously described

82 In ovarian follicle cells, in contrast, Vps4 does not affec

83 lls acquire cell behaviors characteristic of ovarian follicle cells, including incomplete cytokinesis

84 In ovarian follicle cells, localization of Baz at the apica

85 In ovarian follicle cells, loss of Nup54 and Nup58 results

86 lamenco locus, which is expressed in somatic ovarian follicle cells, suggesting a role for piRNAs bey

87 overexpression of sprouty in wing veins and ovarian follicle cells, two other tissues where EGF sign

88 Because the fusilli RNA is present in ovarian follicle cells, we propose that fusilli acts dow

89 nes all contribute to replication control in ovarian follicle cells, which become 16C polyploid and s

90 Here, we utilize the Drosophila ovarian follicle cells, which exhibit re-replication und

91 m requires the activity of the nudel gene in ovarian follicle cells, which provide dorsoventral posit

92 NA requires the action of fettucine (fet) in ovarian follicle cells.

93 recognition complex to specific sites in the ovarian follicle cells.

94 cturally modular protein that is secreted by ovarian follicle cells.

95 ically reduces chorion gene amplification in ovarian follicle cells.

96 s required for Hippo signaling in Drosophila ovarian follicle cells.

97 menco, are specifically expressed in OSS and ovarian follicle cells.

98 promote cellular growth and proliferation in ovarian follicle cells.

99 discs, as well as for gene amplification in ovarian follicle cells.

100 The mammalian ovarian follicle consists of a multilayered complex of s

101 Taken together, these results show that ovarian follicles contain membrane-associated beta-arres

102 ant BaP dose x Gclm genotype interactions on ovarian follicle counts and ovarian tumor multiplicity a

103 In vitro ovarian follicle culture is an active area of research t

104 In the epithelium of Drosophila ovarian follicles, cytoplasm-filled intercellular bridge

105 in ovarian transcriptomes and reductions in ovarian follicle density between juvenile alligators fro

106 Menopause as a result of ovarian follicle depletion is thought to contribute to h

107 e age of 40 and is associated with premature ovarian follicle depletion.

108 Activation of a limited pool of diminishing ovarian follicles determines women's reproductive lifesp

109 WNT5a is required for normal ovarian follicle development and antagonizes gonadotropi

110 beta) superfamily and is required for normal ovarian follicle development and female fertility.

111 EB-containing silicone capsule also reduced ovarian follicle development and significantly inhibited

112 The signals regulating ovarian follicle development and the mechanisms by which

113 many of the signaling pathways orchestrating ovarian follicle development are known, the downstream t

114 inhibition of YAP1 activity disrupted mouse ovarian follicle development in vitro and in vivo.

115 , including cumulus and mural cells), during ovarian follicle development in vivo.

116 hormone receptors, known to be required for ovarian follicle development in vivo.

117 The classical view of ovarian follicle development is that it is regulated by

118 del (Mouse Recon 2) and contains several key ovarian follicle development metabolic pathways.

119 vely studied in multiple organs, its role in ovarian follicle development remains largely unknown.

120 t, they showed reductions in FSH production, ovarian follicle development, and fertility.

121 knockout mice exhibit increased FSH levels, ovarian follicle development, and litter sizes.

122 display reduced fertility due to defects in ovarian follicle development, decreased efficiency of ov

123 able, and the most marked defect is abnormal ovarian follicle development, resulting in impaired fert

124 ls has been limited due to dynamic nature of ovarian follicle development, thus warranting a systems

125 roles for zinc in preceding stages in early ovarian follicle development, when cooperative interacti

126 ds and is necessary for normal embryonic and ovarian follicle development.

127 tocrine/paracrine roles in the regulation of ovarian follicle development.

128 terile and their ovaries exhibited defective ovarian follicle development.

129 processes ranging from muscle contraction to ovarian follicle development.

130 of YAP1 in granulosa cells is essential for ovarian follicle development.

131 ne and that Ced-6 expression correlates with ovarian follicle development.

132 multiple functions of TAF4b during postnatal ovarian follicle development.

133 that the Hippo signaling pathway influences ovarian follicle development; however, its exact roles r

134 ds are the major source of energy supporting ovarian follicles development in mosquitoes.

135 AMH is produced by ovarian follicles during their early growth stages and i

136 were conducted to characterize divergence in ovarian follicle dynamics and transcriptomes between sit

137 melatonin does not confer the protection of ovarian follicles, either directly or indirectly.

138 logous tissues including human placenta, the ovarian follicle epithelium of matrotrophic poeciliid fi

139 tissue and support continuous growth of the ovarian follicle epithelium.

140 Ovarian follicles exhibited structural dysgenesis with g

141 mone/choriogonadotropin receptor (LH/CGR) in ovarian follicles exhibits desensitization of effector a

142 Ovarian follicle formation in Drosophila melanogaster re

143 enile hormone and/or serotonin in Drosophila ovarian follicle formation, but also a cocaine-sensitive

144 The severe oocyte loss observed and lack of ovarian follicle formation, together with the patterns o

145 Primordial and primary ovarian follicles from young female mice were extracted

146 physiological/pathophysiological changes in ovarian follicle functions.

147 ous tissues from the domestic hen, including ovarian follicle granulosa and theca layers.

148 Within the ovarian follicle, granulosa cells (GCs) surround and sup

149 (WNT) signaling pathway in the regulation of ovarian follicle growth and steroidogenesis are now esta

150 Gonadotropins induce ovarian follicle growth that is coincident with increase

151 Within the ovarian follicle, immature oocytes are surrounded and su

152 ur RNA pulldown (FUS, PA2G4 and TRA2beta) in ovarian follicles in a FMR1 premutation mouse model.

153 logically, lesions appear as areas devoid of ovarian follicles in all stages of development that have

154 We address the identity of putative ovarian follicles in Early Cretaceous bird fossils from

155 Primordial ovarian follicles in mice form when somatic cells surrou

156 Ovarian follicles in native and transplanted ovaries wer

157 Mammalian oocytes grow within ovarian follicles in which the oocyte is coupled to surr

158 Maturation of secondary ovarian follicles into corpora lutea, which express high

159 yte and the somatic cell compartments of the ovarian follicle is highly coordinated; this coordinatio

160 The development of fetal ovarian follicles is a critical determinant of adult fem

161 mammalian ovary formation, the production of ovarian follicles is accompanied by an enormous loss of

162 Controlled maturation of ovarian follicles is necessary for fertility.

163 ablished dogma that the initial endowment of ovarian follicles is not supplemented by an appreciable

164 ages of follicular development in laying hen ovarian follicles is not well understood.

165 one/choriogonadotropin receptor (LH/CG R) in ovarian follicles is triggered by activation of ADP-ribo

166 ligand (KL), a product of granulosa cells in ovarian follicles, is a putative regulator of oocyte dev

167 In the Drosophila ovarian follicle, it has been proposed that after Fat2-d

168 m cells can be induced to differentiate into ovarian follicle-like cells (FLCs) in vitro.

169 In the preovulatory ovarian follicle, mammalian oocytes are maintained in pr

170 and molecular processes that regulate mouse ovarian follicle maturation and ovulation with important

171 ion may have physiologic implications during ovarian follicle maturation given that both receptors ma

172 present pharmacological data that Drosophila ovarian follicle maturation requires COX-like activity a

173 h much has been learned about the process of ovarian follicle maturation through studies of oogenesis

174 ovaries showed impaired spermatogenesis and ovarian follicle maturation.

175 regulation of chorion gene expression during ovarian follicle maturation.

176 ic oophorectomies, suggest that depletion of ovarian follicles might underlie the epidemiological fin

177 eroids promoted oocyte maturation in several ovarian follicle models, doing so by signaling through c

178 lso greatest on high P:C diets (1:1) whereas ovarian follicle number was greatest on P:C 3:1 associat

179 We observed no effects on F3 ovarian follicle numbers with either of the shorter dosi

180 In rodents, the formation of ovarian follicles occurs after birth.

181 lly expressed between lines in the ovary and ovarian follicles of different size classes, respectivel

182 In preovulatory ovarian follicles of mice, meiotic prophase arrest in th

183 In ovarian follicles of Oncopeltus fasciatus, and of Xyloco

184 the transcriptional landscape of laying hen ovarian follicles, offering a foundation for further exp

185 The Drosophila ovariole tip produces new ovarian follicles on a 12-hour cycle by controlling nich

186 Exposure to CY75X4 reduced the loss of ovarian follicles (p < 0.05), and body weight (p < 0.001

187 ls is critical for the normal development of ovarian follicles, perturbations in oocyte-GC communicat

188 Thus, although the somatic compartment of ovarian follicles plays an essential role in the mainten

189 ood from germ-line stem cells to sustain the ovarian follicle pool has recently generated controversy

190 izing the role of Foxo3 as a guardian of the ovarian follicle pool in mammals and a potential determi

191 rgely results from the depletion of a finite ovarian follicle pool that is produced during embryonic

192 Women with FXPOI have a depleted ovarian follicle population, resulting in amenorrhea, hy

193 ritical for LH-induced steroid production in ovarian follicles, probably through matrix metalloprotei

194 oidogenesis, breast and prostate growth, and ovarian follicle recruitment, all of which are processes

195 Rupture of the ovarian follicle releases the oocyte at ovulation, a tim

196 stem cells in vitro, but generating a human ovarian follicle remains a challenge.

197 kout or pharmacological inhibition preserved ovarian follicle reserve after radiation and chemotherap

198 During female reproductive life, ovarian follicle reserve is reduced by maturation and at

199 The ovarian follicle reserve, formed pre- or perinatally, co

200 Cancer treatments can damage the ovarian follicle reserve, leading to primary ovarian ins

201 females were assessed for estrous cyclicity, ovarian follicle reserve, oocyte functional competence,

202 one acetate (DMPA) inhibits proliferation of ovarian follicles, resulting in anovulation and a decrea

203 VCD is shown to selectively destroy small ovarian follicles, resulting in early depletion of funct

204 sts have long realized the importance of the ovarian follicle's somatic cells in nurturing oogenesis

205 and isolated cells, we showed in vitro that ovarian follicles secrete factor(s) that suppresses the

206 /UAS transgene programming during Drosophila ovarian follicle stem cell differentiation and used them

207 og (Hh) signaling in Drosophila melanogaster ovarian follicle stem cells (FSCs) induces the activity

208 We have used Drosophila ovarian follicle stem cells (FSCs) to study how stem cel

209 an unbiased genetic screen using Drosophila ovarian follicle stem cells to probe essential functions

210 ces apoptotic death in cultured cells and in ovarian follicles, suggesting apoptosis as a mechanism o

211 osa cell gene expression required for normal ovarian follicle survival and proliferation in response

212 Interestingly, the rerouted FSH enhanced ovarian follicle survival, caused a dramatic increase in

213 In developing ovarian follicles, the regulation of cell proliferation

214 ic dorsal-ventral polarity originates in the ovarian follicle through the restriction of pipe gene ex

215 y low levels of caspase-1 mRNA expression in ovarian follicle tissues plus the inability of IL-1beta

216 e coordination of multiple events within the ovarian follicle to ensure ovulation of a fertilizable e

217 w that a microfluidic system supports murine ovarian follicles to produce the human 28-day menstrual

218 Luteinizing hormone (LH) acts on ovarian follicles to reinitiate meiosis in prophase-arre

219 (LH) acts on the somatic cells of vertebrate ovarian follicles to stimulate meiotic resumption in the

220 esponse of LH/CG R-stimulated AC activity of ovarian follicles to the preovulatory surge of LH can be

221 The majority of ovarian follicles undergo atresia, a hormonally controll

222 Ovarian follicles undergo exponential growth in response

223 ltihour imaging of both compartments of live ovarian follicles, using mice expressing an improved cAM

224 rease in vitellogenin yolk protein uptake in ovarian follicles were observed by western blots in ODC-

225 pecifically in granulosa cells of developing ovarian follicles where it regulates the late stages of

226 rge initiates a cascade of events within the ovarian follicle which culminates in ovulation.

227 r brn and weak grk or Egfr mutations produce ovarian follicles with multiple sets of nurse cell-oocyt

228 arian inflammation to the growing and mature ovarian follicles, with destruction of the ovarian funct

229 An in vitro model of human ovarian follicles would greatly benefit the study of fem

230 lates the growth and development of multiple ovarian follicles, yielding heterogeneous oocytes with v