ライフサイエンスコーパス: oxo

1 ated fifth (or isocyclic) ring bearing 13(1)-oxo and 13(2)-carbomethoxy substituents.

2 (DOPO(q); DOPO = 2,4,6,8-tetra- tert-butyl-1-oxo-1 H-phenoxazin-9-olate) was prepared.

3 ylide [2-(3,4-dihydro-2 H-pyrrolium-1-yl)-1-oxo-1 H-inden-3-olate, DHPO] to differently substituted

4 ying basicity of the decaniobate ([Nb(10) ]) oxo-caps can be exploited to build 1D, 2D, and 3D inorga

5 demonstrate that the more potent analogue 11-oxo-12S-hydroxylithocholic acid methyl ester (BAA473) ca

6 nts with JA, methyl jasmonate, or cis-(+)-12-oxo-phytodienoic acid restored wild-type levels of resis

7 fungus Trichoderma virens and identified 12-oxo-phytodienoic acid (12-OPDA) and alpha-ketol of octad

8 s and herein report the identification of 12-oxo-lithocholic acid (BAA485), a potential microbiome-de

9 that the constitutively higher levels of 12-oxo-phytodienoic acid (OPDA) in Mp708 plants contributed

10 aled significantly higher basal levels of 12-oxo-phytodienoic acid, a precursor in the jasmonic acid

11 The level of 15-oxo-eicosatetraenoic acid (15-Oxo-ETE), a downstream pro

12 -oxo-1,3-diarylpropyl)malononitrile and 2-(2-oxo-2-arylethyl)malononitrile, respectively, under mild

13 ave differences in expression profiles and 2-oxo substrate preferences, which account for the diversi

14 mation of the 2-oxo-1,2-oxaphosphinane and 2-oxo-1,2-oxaphospholane ring systems in different carbohy

15 -2 H-benzo[ h]chromene-3-carbonitriles and 2-oxo-2,5-dihydrothiochromeno[4,3- b]pyran-3-carbonitriles

16 aminoaryl N-monosubstituted hydrazones and 2-oxo-3-butenoates under Bronsted acid catalysis, has been

17 4-phenylbutyl)oxazole-3-carboxamide 8a and 2-oxo-5-phenyl-N-(4-phenylbutyl)oxazole-3-carboxamide 12a,

18 controlling the specificity for different 2-oxo substrates and the determinants of side chain length

19 chemical optimization of our initial hits, 2-oxo-4-phenyl-N-(4-phenylbutyl)oxazole-3-carboxamide 8a a

20 N-(2-(Hydroxyamino)-2-oxo-1-(3',4',5'-trifluoro-[1,1'-biphenyl]-4-yl)ethyl)-4-

21 actonization via a denitration reaction of 2-oxo-5,6-dihydro-2 H-benzo[ h]chromene-3-carbonitriles an

22 -[4-fluoro-2-(1-methyl-4-piperidyl)phenyl]-2-oxo-N-pentyl-oxazole-3-carboxamide 32b as a potent AC in

23 The structure and conformation of the 2-oxo-1,2-oxaphosphinane and 2-oxo-1,2-oxaphospholane ring

24 2-aminobenzaldehyde arylhydrazones toward 2-oxo-3-butenoates to afford (E)-diazoaryl-benzo[b]azepine

25 provided alternative redox signaling when 2-oxo-isocaproate or fatty acid oxidation formed superoxid

26 t study of FtmOx1, a fungal iron(II)- and 2-(oxo)glutarate-dependent oxygenase that installs the endo

27 d along the Jahn-Teller axis due to the u(3)-oxo and u-oxime bridges.

28 g after photoexcitation of a trinuclear u(3)-oxo-bridged Mn(III)-based SMM, whose magnetic anisotropy

29 3-oxo-C12-HSL disrupts mitochondrial morphology, attenuate

30 lyzed coupling of arylboronic acid with 2-(3-oxo-1,3-diarylpropyl)malononitrile and 2-(2-oxo-2-arylet

31 ecular acceptor of TrBTIC (2,7,12-tris((2-(3-oxo-2,3-dihydroinden-1-ylidene)malononitrile-7-benzothia

32 -)truxene) is designed by attaching the 2-(3-oxo-2,3-dihydroinden-1-ylidene)malononitrile-benzothiadi

33 A series of 2-(3-oxo-2H-[1,2,4]triazino[5,6-b]indol-5(3H)-yl)acetic acid

34 hase redistribution process between the 2-(3-oxo-indan-1-ylidene)-malononitrile-derived end-groups (E

35 OH was crucial: 3-acetylated, 3-deoxy, and 3-oxo analogs of 3alpha5alpha-P, as well as 3beta-OH analo

36 on in 4-vinylguaiacol, acetovanillone, and 3-oxo-alpha-ionol, providing spicy and fruity notes at the

37 of our lead compound 1 (( Z)-2-benzylidene-3-oxo-2,3-dihydrobenzofuran-7-carboxamide; PARP-1 IC(50) =

38 hibition in cellular respiration caused by 3-oxo-C12-HSL.

39 of allelopathic 3-hydroxy-alpha-damascone, 3-oxo-alpha-ionol, 3-oxo-7,8-dihydro-alpha-ionol (Blumenol

40 reduce virulence and abate dermonecrosis: 3-oxo-olean-12-en-28-oic acid (1), 3-oxotirucalla-7,24Z-di

41 ses to dienone compounds with a 1,5-diaryl-3-oxo-1,4-pentadienyl pharmacophore have been studied exte

42 diyl)bis(methanylylidene))bis(5,6-difluoro-3-oxo-2,3-dihydro-1H-indene-2,1-diylidene))dimalononitrile

43 accumulation of intermediates derived from 3-oxo-mycolate precursors.

44 s to a new series of biorelevant 2-hydroxy-3-oxo-2,3-dihydrobenzofuran-2-carboxamides and 2-hydroxy-3

45 drobenzofuran-2-carboxamides and 2-hydroxy-3-oxo-2,3-dihydrobenzofuran-2-carboxylates using rose beng

46 -ring of the steroid metabolite 17-hydroxy-3-oxo-4-pregnene-20-carboxyl-CoA (17-HOPC-CoA).

47 ydroxy-alpha-damascone, 3-oxo-alpha-ionol, 3-oxo-7,8-dihydro-alpha-ionol (Blumenol C), and 3-hydroxy-

48 1-ethyl-5-methoxy-1H-indol-3-yl)methylene)-3-oxo-2,3-dihydrobenzofuran-6-yl)oxy)acetonitrile (5a) and

49 - b']dithiophene-2,8-diyl]-bis[methylidyne(3-oxo-1 H-indene-2,1(3 H)-diylidene)]]bis[propanedinitrile

50 strate that the P. aeruginosa QS molecule, 3-oxo-C12-HSL, alters mitochondrial pathways critical for

51 In vivo, P. aeruginosa releases N-(3-oxo-dodecanoyl) homoserine lactone to suppress host immu

52 N-(3-oxo-dodecanoyl) homoserine lactone, the autoinducer of t

53 at this efflux pump extrudes the QS signal 3-oxo-C12-HSL, we show otherwise.

54 Mechanistically, we show that 3-oxo-C12-HSL attenuates expression of peroxisome prolifer

55 g opening of oxepin-CoA and converts it to 3-oxo-5,6-dehydrosuberyl-CoA.

56 es barrier integrity in cells treated with 3-oxo-C12-HSL.

57 leophilic acyl substitution reaction of 2-(4-oxo-2-thioxothiazolidin-5-ylidene)acetates and alpha,alp

58 tive compound, 4-(dimethylamino)-N-(3-{2-[(4-oxo-4H-chromen-7-yl)oxy]acetamido}phenyl) (12j).

59 The lipid aldehyde 4-oxo-2-nonenal (ONE) is a highly reactive protein crossli

60 enal (HHE), 4-hydroxy-2-nonenal (HNE), and 4-oxo-2-nonenal (ONE) in cod liver-, anchovy-, krill-, and

61 reover, different epsilon-apoluteinals and 4-oxo-apo-beta-carotenals were detected in Capsicum specie

62 In this study, a small molecule CM14 [N-(4-oxo-4H-thieno[3,4-c]chromen-3-yl)-3-phenylprop-2-ynamide

63 oped beginning with N-TIPS-pyrrole or with 4-oxo-2-pentene and TosMIC, affording multi-gram-quantitie

64 ing the epimerization of RS to RR via (4R)-5-oxo-4-decanolide (ODL) as intermediate.

65 odrug of the glutaminase inhibitor 6-diazo-5-oxo-L-norleucine (DON) ameliorates social avoidance and

66 6-Diazo-5-oxo-l-norleucine (DON) is a glutamine antagonist with ro

67 ploy a broad glutamine antagonist, 6-diazo-5-oxo-l-norleucine (DON), to target a metabolic program th

68 a small molecule glutamine analog (6-diazo-5-oxo-l-norleucine [DON]).

69 otent than the known GGT inhibitor 6-diazo-5-oxo-l-norleucine and are not toxic toward human embryoni

70 pound (3-amino-N-(3-chloro-2-methylphenyl)-5-oxo-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxami

71 to previously reported 1,2,3,5-tetrahydro-5-oxo-imidazo[1,2-a]pyridine-7-carboxylic acid (IPCA).

72 protodecarboxylation of the corresponding 6-oxo nicotinic acid to furnish 2-pyridone.

73 ermediate of the Dornow reaction-5-hydroxy-6-oxo-4-aryl-6H-1,2-oxazine-3-carboxylates.

74 tion sequence for the synthesis of various 6-oxo nicotinic acid esters is described.

75 more complex oxocarboxylic acids (oxo-C(7) + oxo-C(8)).

76 particularly susceptible to oxidation, and 8-oxo-dG (OG), when produced in situ or incorporated by DN

77 des are commonly misinserted into DNA, and 8-oxo-G causes replication errors, we were motivated to in

78 ir (NER), binds avidly to abasic sites and 8-oxo-guanine (8-oxoG), suggesting a noncanonical role in

79 yde provokes modifications of RNAs such as 8-oxo-7,8-dihydroguanine (8-oxoG) and the role that these

80 DNA damage, as reflected by the biomarkers 8-oxo-G, gammaH2AX and pATM were reduced in conditioned ve

81 nucleobase whose deoxyribonucleotide form, 8-oxo-dGTP, has been widely studied and demonstrated to be

82 Second, free 8-oxo-dGTP can be misincorporated by DNA polymerases into

83 ances in duplex DNA, ultimately generating 8-oxo-7,8-dihydroguanine at a redox-sensitive sequence suc

84 8-Oxo-7,8-dihydro-2'-guanosine (8-oxo-G) is a common oxidized nucleobase whose deoxyribonu

85 use of mutation due to oxidative damage is 8-oxo-2'-deoxyguanosine (8-oxoG) mispairing with adenine (

86 d opposite the oxidatively damaged lesion, 8-oxo-7,8-dihydroguanine (OG), to initiate base excision r

87 Moreover, 8-oxo-guanine impedes EXO1 but enhances resection by BLM-D

88 rimary pathway to remove the pre-mutagenic 8-oxo-7,8-dihydroguanine (8-oxoG) from DNA.

89 Addition of 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodGuo) as a sacri

90 damage-as indicated by the accumulation of 8-oxo-dG and gammaH2AX-which was suppressed by the NADPH o

91 instead of deoxyribonucleotides, opposite 8-oxo-2'-deoxyguanosine (8-oxodG) are efficiently ligated

92 al of adenine (A) misincorporated opposite 8-oxo-7,8-dihydroguanine (OG).

93 hosphorylated heavy chain), DNA oxidation (8-oxo-2'-desoxyguanosine), lipid peroxidation (4-hydroxy-2

94 bstitutions with the major product of ROS, 8-oxo-7,8-dihydroguanine ((oxo)G), and evaluated the G-qua

95 bed DNA break repair containing a template 8-oxo-7,8-dihydro-2'-guanosine (8OG) by Family X Polymeras

96 site dA, respectively, indicating that the 8-oxo moiety greatly facilitated error-prone replication.

97 xidation of the guanine (G) heterocycle to 8-oxo-7,8-dihydroguanine (OG) in mammalian gene promoters

98 on of DNA by ROS drives conversion of G to 8-oxo-7,8-dihydroguanine (OG) to mark target promoters for

99 graphic analyses revealed that, similar to 8-oxo-dGTP, r8-oxo-GTP adopts an anti conformation opposit

100 However, unlike 8-oxo-dGTP, r8-oxo-GTP did not form a planar base pair wit

101 holine, lysophosphocholine, 1-palmitoyl-2-(9-oxo-nonanoyl)- sn-glycero-3-phosphocholine, 1-palmitoyl-

102 w photocage, {bis[(2-pyridyl)methyl]amino}(9-oxo-2-xanthenyl)acetic acid (XDPAdeCage, 1), which utili

103 3-oxobutan-2-yloxy)-2-hydroxypropanoic acid (oxo-C(7) product), and 2-(1-carboxy-1-hydroxyethoxy)-2-m

104 -hydroxyethoxy)-2-methyl-3-oxobutanoic acid (oxo-C(8) product) are formed under all conditions invest

105 ry forming more complex oxocarboxylic acids (oxo-C(7) + oxo-C(8)).

106 arrangement can be readily realized by alpha-oxo gold carbenes oxidatively generated from TBS-termina

107 this strategy, one of the hallmarks of alpha-oxo carbene/carbenoid chemistry, that is, the Wolff rear

108 oxides offer direct access to reactive alpha-oxo gold carbene intermediates from benign and readily a

109 ZrT(d), an oxo-centered tetrahedron fully formulated [Zr(4)(OH)(4)(

110 ing product states of many FDOs, it lacks an oxo-bridge.

111 r its NMO complex, through protonation of an oxo ligand to give more electrophilic species.

112 enated species including terminal peroxo and oxo complexes, (O(2))Zr(MesNP (i)Pr(2))(3)CoCN (t)Bu (2)

113 ring-opening metathesis polymerization, and oxo/imido heterometathesis.

114 om reductions of these iron(IV)-hydroxo and -oxo porphyrin species that are within 1 kcal/mol of expe

115 importantly, tetragonal iron(V)-nitrido and -oxo complexes 1-3 and 5 all possess an orbitally nearly

116 hat tetragonal low spin iron(V)-nitrido and -oxo complexes feature electronic structures akin to thos

117 Iron(V)-nitrido and -oxo complexes have been proposed as key intermediates in

118 l-characterized genuine iron(V)-nitrido and -oxo complexes, [Fe(V)(N)(MePy(2)tacn)](PF(6))(2) (3, MeP

119 after O-insertion, namely a rare arylbismuth oxo dimer and a unique monomeric arylbismuth hydroxide.

120 nyl)hydrazinylidene]-5-(1,1-dimethylethyl)-b-oxo-3-isoxazolepropanenitrile.

121 ons on the regiochemical effects of the beta-oxo-auxochrome.

122 This study examined biodegradable, oxo-biodegradable, compostable, and high-density polyeth

123 -surface dimerization to give surface-bound, oxo-bridged dimers.

124 ransition-metal complexes, H-abstractions by oxo-metal species, ionic cleavage of halogen bonds, meth

125 duced hydrogen-bonding capability caused by (oxo)G, a loss of G-quadruplex structure was observed for

126 The C19-oxo-functionalized eburnane alkaloids display unique che

127 educed to two O(2-), that create two Cu-O-Ce oxo-bridges at 453 K.

128 r molecules via hydroxylation of the cluster oxo bridges for all investigated clusters.

129 gy for stabilization of the molecular cobalt-oxo cubane core (Co(4)O(4)) by immobilizing it as part o

130 petition between each target and competitive oxo-anion pair is classified.

131 of competition between target and competitor oxo-anions to sorb on commonly used, nonselective, metal

132 ecreases at the expense of CO(4) and complex oxo-carbon polymers (C(x)O(y)) displaying multiple C-C b

133 cribed through a sequential cyclopropanation/oxo-amination.

134 nd in vivo and find the synthetic derivative oxo-aglaiastatin to possess such activity.

135 r product of ROS, 8-oxo-7,8-dihydroguanine ((oxo)G), and evaluated the G-quadruplex forming ability o

136 s a four-helix bundle motif and has a diiron oxo cofactor that binds oxygen.

137 e catalytic power was established for direct oxo-scissoring of a wide range of alkenes to furnish ald

138 ased cation charge decreases selectivity for oxo-site bonding, leading to higher dimensional linking.

139 g conformation, while a novel residue, gamma-oxo-delta-azaproline, features rapid amide isomerization

140 These compounds make use of hard oxo donors as hydroxamate or catecholate groups to coord

141 ) pyrazine nitrate selectively traps harmful oxo-anions from water such as permanganate, perrhenate a

142 The 16-palladium(II)-oxo cluster [Pd(16) O(24) (OH)(8) ((CH(3) )(2) As)(8) ]

143 The 24-palladium(II)-oxo cluster [Pd(24) O(44) (OH)(8) ((CH(3) )(2) As)(16) ]

144 e(34) ], bulk iron oxides, previous Fe(III) -oxo cages, and polyoxometalates (POMs), hints that much

145 nclusion that C-H activation by this Co(III)-oxo complex proceeds by a p K(a)-driven "asynchronous" c

146 The reactivity of the Fe(III)-oxo center in proton-coupled electron transfer with X-H

147 been synthesized bearing a terminal Fe(III)-oxo center stabilized by hydrogen-bonding interactions f

148 allenging to link into frameworks; the inert oxo-caps that provide solubility are resistant to replac

149 lfides and benzyl alcohols by a nonheme iron-oxo complex have been studied.

150 orrelated with slight elongation of the iron-oxo bond with increasing donation from the axial ligands

151 me iron systems to form the high-valent iron-oxo intermediates.

152 rom a substrate C-H bond by high-valent iron-oxo oxidants is already encoded in the HAA step when the

153 e iron(III)-hydroperoxo and high-valent iron-oxo species have been trapped and identified in investig

154 nzymes use O(2) to generate high valent iron-oxo species to homolyze unactivated C-H bonds in substra

155 uranose appears to be less reactive than its oxo counterpart, the thio- ara-, lyxo-, and xylo-furanos

156 on(V)-nitrido species and contrasts with its oxo congener, compound I, which contains a ferryl unit i

157 The protonation state of the iron(IV) oxo (or ferryl) form of ascorbate peroxidase compound II

158 ically characterized synthetic heme iron(IV) oxo complexes, F(8)Cmpd-II (F(8) = tetrakis(2,6-difluoro

159 A basic iron(IV) oxo species has yet to be spectroscopically observed in

160 Our data indicate that APX-II is an iron(IV) oxo species with an Fe-O bond distance of 1.68 angstrom,

161 ) that leads to the formation of the Fe(IV) -oxo and release of water through a concerted mechanism.

162 wards the selective generation of an Fe(IV) -oxo intermediate.

163 The Fe(IV) -oxo species was characterized by UV/Vis absorption and M

164 The reaction starts with an Fe(IV) -oxo-catalyzed hydroxylation.

165 e of a redox-active Ce(4+) ion-bound Mn(IV) -oxo complex and its spectroscopic characterization and c

166 e water nucleophilic attack to single Co(IV)-oxo or Co(III)-oxyl centers.

167 Diiron(IV)-oxo species are proposed to effect the cleavage of stron

168 eed through C-H bond activation by an Fe(IV)-oxo species, followed by azido-directed C=N bond formati

169 is drastically different from nonheme Fe(IV)-oxo synthetic model complexes; (3) The OAT step most lik

170 (HAT) from a substrate carbon to an iron(IV)-oxo (ferryl) intermediate initiates a diverse array of e

171 endent (Fe/2OG) oxygenases generate iron(IV)-oxo (ferryl) intermediates that can abstract hydrogen fr

172 esaturation and hydroxylation by an iron(IV)-oxo active-site model.

173 ries of hydrocarbons by the nonheme iron(IV)-oxo complex [(N4Py)Fe(IV)=O](2+) is efficiently mediated

174 e are consistent with the catalytic iron(IV)-oxo complex being able to support the coordination of an

175 ates O(2) to form the corresponding iron(IV)-oxo complex, 2-trans, via a mechanism reminiscent of the

176 Herein, various axially ligated iron(IV)-oxo complexes were prepared to examine the influence of

177 hat splits homolytically to form an iron(IV)-oxo heme (Compound II) and a free NO(2) radical via a sm

178 e first reported synthetic H-bonded iron(IV)-oxo heme systems were made in the presence of the protic

179 We posit that an iron(IV)-oxo intermediate that stably forms under a low-coordinat

180 re unpredicted pathway involving an iron(IV)-oxo species, Fe(4+)=O.

181 geometric structures of these heme iron(IV)-oxo species.

182 often is performed by a high-valent iron(IV)-oxo species.

183 avage of dioxygen often produces an iron(IV)-oxo that has been characterized in a number of enzymatic

184 A mononuclear nonheme manganese(IV)-oxo complex binding the Ce(4+) ion, [(dpaq)Mn(IV) (O)](+

185 esized a well-defined silica-supported W(IV)-oxo species, (=SiO)WO(OtBuF(6))(py)(3) (F6@SiO(2-700); O

186 ty and initiation mechanism of surface W(IV)-oxo species, we synthesized a well-defined silica-suppor

187 tivation mechanism, like the molecular W(IV)-oxo species.

188 It has been proposed that reduced W(IV)-oxo surface species act as precatalysts.

189 reduction of other important heavy non-metal oxo species (e.g., SiO(2), phosphine oxides, SO(2)) with

190 ized and characterized late transition metal oxo complex PhB ( (t)BuIm)(3)Co(III)O.

191 C-H activation by transition metal oxo complexes is a fundamental reaction in oxidative che

192 ation reactions mediated by transition metal oxo complexes.

193 ity paradigm for many other transition metal oxo complexes.

194 risons both with carbon and transition metal oxo species.

195 Metal-oxo clusters offer an opportunity to assemble inorganic

196 Reduction of d(2) metal-oxo ions of the form [MO(PP)(2) Cl](+) (M=Mo, W; PP=chel

197 erplay between electrolyte cations and metal-oxo species opens an avenue for controlling the formatio

198 ating three high-Z components-Hf-based metal-oxo clusters, Ir-based bridging ligands, and W-based pol

199 oxidative cyclization of 1,5-dienes by metal-oxo species is a powerful method for stereocontrolled sy

200 the formation of intrinsically chiral metal-oxo frameworks.

201 erein, we report that discrete hafnium metal-oxo cluster [Hf(18) O(10) (OH)(26) (SO(4) )(13) .(H(2) O

202 (POMs) represent an important group of metal-oxo nanoclusters, typically comprised of early transitio

203 e a large group of anionic polynuclear metal-oxo clusters with discrete and chemically modifiable str

204 While generating stable metal-oxo species for late transition metals remains synthetic

205 Fe(IV)=O intermediates with a terminal metal-oxo moiety are key oxidants in many enzymatic and synthe

206 e), for their ability to form terminal metal-oxo sites and subsequently activate the C-H bond of meth

207 The electronic structure of the metal-oxo active site is analyzed for each combination of meta

208 High-valent transition metal-oxo, -peroxo, and -superoxo complexes are crucial interm

209 donor in the generation of high-valent metal-oxo complexes.

210 O-O bond cleavage, and the reactivity of Mn oxo intermediates.

211 xample of a well-defined silica-supported Mo oxo alkylidene, which is an analogue of the putative act

212 This Mo oxo metathesis catalyst also outperforms its correspondi

213 Grafting a molybdenum oxo alkylidene on silica (partially dehydroxylated at 70

214 orts have been made to synthesize molybdenum-oxo complexes of different ligand environments.

215 ng alkyl hydroperoxides, that the molybdenum-oxo moiety is an active catalytic species.

216 ated six-coordinate iron center lacking a mu-oxo bridge.

217 R2lox cofactor to an R2c-like cofactor, a mu-oxo/mu-hydroxo-bridged Mn(III)/Fe(III) dimer.

218 wis acid Sc(3+) and transforms into a bis(mu-oxo)diiron(IV) complex, thus providing a synthetic prece

219 sMMO-Q was previously reported as a bis-mu-oxo Fe(IV)(2)(mu-O)(2) diamond core but was recently des

220 ntermediate (high-valent diamond-core bis-mu-oxo-[Fe(IV)](2) unit) is involved in the reaction mechan

221 Fe dimer is linked by two oxygen bridges (mu-oxo/mu-hydroxo), whereas in R2lox, a two-electron oxidan

222 ting the first structurally characterized mu-oxo, mu-nitrosyl metal complex.

223 lex with nitric oxide produces a dicopper mu-oxo, mu-nitrosyl complex [LCu(2)(mu-O)(mu-NO)](2+), repr

224 ly, reacts with water to form an isolable mu-oxo bis-cubane complex [(py)(3)(OAc)(4)Co(3)(mu(3)-O)(4)

225 he synthesis and characterization of two new oxo-molybdenum(V)-corrolato complexes are described here

226 Putative, high-valent nickel-oxo or nickel-oxyl intermediates have been proposed to c

227 eric, homoleptic, all-oxygen-ligated but non-oxo 4d(1) Mo(V) complex known to date; as such, it prove

228 enging, notably, a number of high-valent non-oxo-metal species of late transition metals have been re

229 Five "competing" co-occurring oxo-anions (phosphate, sulfate, bicarbonate, silicate, a

230 ve competition between commonly co-occurring oxo-anions in water and mechanistic approaches for the d

231 competitive adsorption between co-occurring oxo-anions, overestimating realistic pollutant removal p

232 The biological activity of oxo-aglaiastatin was shown to be a consequence of inhibi

233 The catalytic application of oxo-molybdenum(V)-corrolato complexes in the epoxidation

234 eranions in solution on the self-assembly of oxo clusters.

235 respect, the energy-intense deoxygenation of oxo compounds of silicon, phosphorus, and sulfur is of p

236 Other examples of oxo-group functionalization of [U(VI)O(2)](2+) that do n

237 s, critically establishing the importance of oxo H-bonding (or protonation) in heme complexes and enz

238 A series of oxo-phenylacetyl (OPAc)-protected saccharides, with dive

239 Accommodation of (oxo)G at sites originally in syn or anti in nonsubstitut

240 we report a photoredox-coupled ring-opening oxo-amination of electronically unbiased cyclopropanes,

241 (8) ] (Pd(16) ) comprises a cyclic palladium-oxo unit capped by eight dimethylarsinate groups.

242 he first three examples of neutral palladium-oxo clusters (POCs).

243 derivative of Pd(16) with a tetra-palladium-oxo unit grafted on either side.

244 We anticipate that polymerized oxo-carbon species were a significant reservoir for carb

245 mechanistically driven access to polynuclear oxo clusters and related materials remains a grand chall

246 Based on mechanistic studies, the present oxo-amination is proposed to proceed through an S(N)2-li

247 ymerase beta (pol beta) and characterized r8-oxo-GTP insertion with DNA substrates containing either

248 ses revealed that, similar to 8-oxo-dGTP, r8-oxo-GTP adopts an anti conformation opposite a templatin

249 However, unlike 8-oxo-dGTP, r8-oxo-GTP did not form a planar base pair with either temp

250 has a diminished catalytic efficiency for r8-oxo-GTP compared with canonical deoxyribonucleotides but

251 and provide structural insights into how r8-oxo-GTP is processed by DNA polymerases.

252 These results suggest that r8-oxo-GTP is a potential mutagenic substrate for DNA polym

253 h canonical deoxyribonucleotides but that r8-oxo-GTP is inserted mutagenically at a rate similar to t

254 bonucleotides are analogously oxidized to r8-oxo-GTP, which can constitute up to 5% of the rGTP pool.

255 r conformational changes of pol beta with r8-oxo-GTP, we demonstrate impaired pol beta closure that c

256 Si(7)O(11)(OH)}UO(2)], which undergoes rapid oxo silylation by HN(SiMe(3))(2), followed by silyloxy l

257 terocycles, which can be converted to a rare oxo complex [{Th(Tren(TIPS) )(mu-ORb)}(2) ] (6) and the

258 As part of our efforts to develop rhenium-oxo corroles as photosensitizers for oxygen sensing and

259 st spectroscopically characterized high spin oxo-Fe(V) complex and constitutes a paradigmatic example

260 e trans to the oxo atom in 2 with subsequent oxo-hydroxo tautomerism for its incorporation as the oxo

261 hemical reduction routes to deoxygenate such oxo precursors produce tons of reagent waste or, in the

262 resulting in decreased removal of the target oxo-anions.

263 ue to their potential to compete with target oxo-anions for sorption sites resulting in decreased rem

264 Six "target" oxo-anion pollutants (arsenate, arsenite, selenate, sele

265 between the metal binding site and terminal oxo ligand during the C-H activation process can greatly

266 The oxo cubane oxidizes organic substrates and, notably, rea

267 r(i) (2) CH(Me)CH(2) C(O)mu-P]}] (3) and the oxo complex [{Th(Tren(TIPS) )(mu-OCs)}(2) ] (7) were iso

268 oxo tautomerism for its incorporation as the oxo atom of 1.

269 ed by radical coupling reactions between the oxo cubane and both 2,4,6-tri-tert-butylphenoxyl and tri

270 cally coupled through the H-bond between the oxo(Fe) and hydroxo(Cu) ligands, while the Cu(II) and Ty

271 whereas those with phosphines that leave the oxo ligand exposed are more reactive and observed transi

272 For each mechanism, the oxo-anions, both target and competitors, are ranked in t

273 xpected trigonal bipyramidal geometry of the oxo complex [U(O)(NP(pip)(3))(4)], 2-U(PN)O.

274 uranyl ion which entailed conversion of the oxo ligands into siloxy ligands and reductive metalation

275 ology, differing only in the position of the oxo unit bound to the iron center.

276 The efficacy of the oxo-molybdenum(V)-corrolato complexes for the catalytic

277 d we find that spin density localized on the oxo ligand is not an inherent requirement for low C-H ac

278 atives with bulky phosphines that shield the oxo ligand are stable enough to be isolated, whereas tho

279 d spectroscopic experiments suggest that the oxo- and thiosquaramide bolaamphiphiles self-assemble in

280 It is therefore not clear that the oxo-biodegradable or biodegradable formulations provide

281 These results indicate that the oxo-centered reactivity of d(3) complexes may be control

282 ect binding of a water molecule trans to the oxo atom in 2 with subsequent oxo-hydroxo tautomerism fo

283 ramolecular nucleophilic oxygen close to the oxo group to facilitate O-O bond formation and at a late

284 er with triethylsilane, reminiscent of their oxo counterparts.

285 res can be efficiently desulfurized to their oxo derivatives, thus restoring strong emission of the f

286 design of a new nMOF, Ti-TBP, composed of Ti-oxo chain secondary building units (SBUs) and photosensi

287 Due to (oxo) G's preference for the syn conformation, distinct r

288 the importance of the heterogeneous tungsten-oxo-based olefin metathesis catalyst (WO(3)/SiO(2)) in i

289 , strongly covalent, and chemically robust U-oxo groups.

290 on reductive functionalization of the uranyl oxo groups has been discovered and developed.

291 gands and reductive metalation of the uranyl oxo with Group 1 and f-block metals.

292 is capable of accessing a high-valent Mn(V)-oxo species which can transfer an O atom to a thioether

293 Redox activity of the Ru(V)-oxo fragment is easily tuned by the electron-donating ab

294 High-valent Ru(V)-oxo intermediates have long been proposed in catalytic o

295 the [Co(3)O(4)] unit in supporting the Ru(V)-oxo moiety via a strong pai-electron donation.

296 e featuring an isolable, yet reactive, Ru(V)-oxo moiety.

297 nificant oxyl radical character in the Ru(V)-oxo unit is experimentally demonstrated by radical coupl

298 re with a molecular catalyst of vanadium (V)-oxo dimer.

299 s by retaining or switching to a fold where (oxo)G is in syn conformation.

300 e were found to tolerate substitutions with (oxo)G.