ライフサイエンスコーパス: pair bond

1 athways interact in the establishment of the pair bond.

2 onditioned partner preference, observed as a pair bond.

3 r bonded baseline after the dissolution of a pair bond.

4 ng that is necessary to maintain the initial pair bond.

5 n, expression, and maintenance of monogamous pair bonds.

6 n species differences in the ability to form pair bonds.

7 productive activation or to the formation of pair bonds.

8 anges that result in the formation of stable pair bonds.

9 ing partner health and maintaining long-term pair bonds.

10 attributed to paternal provisioning based on pair bonds.

11 er pairs typically show strong and selective pair bonds.

12 ion (STI) in populations with such ephemeral pair bonds.

13 d birds with multi-year, socially monogamous pair bonds.

14 s of jackdaws, a species that forms lifelong pair-bonds.

15 ial sex differences in the CRF modulation of pair bonding.

16 nsible for the enduring nature of monogamous pair bonding.

17 thin these subregions differentially mediate pair bonding.

18 ned the effects of repeated AMPH exposure on pair bonding.

19 of brain regions previously associated with pair-bonding.

20 direct evidence for epigenetic regulation of pair-bonding.

21 tion of selective aggression associated with pair-bonding.

22 We propose that long-term pair bonds, affinal kin recognition, exogamy, and multi-

23 ike many other rodents, they are gregarious, pair bond after copulating, and are biparental.

24 ocially monogamous rodent species that forms pair bonds after mating, a behavior in which central dop

25 ially monogamous rodent that forms long-term pair bonds after mating--we demonstrate that amphetamine

26 contributes to the neuroprotective effect of pair bonding against drug reward.

27 us Peromyscus maniculatus, the disruption of pair bonds altered the size and morphology of spheroids

28 ful of primates that, like humans, routinely pair bond and care cooperatively for their young.

29 aracterized their aggression associated with pair bonding and examined the related neuronal activatio

30 ributors to the effects of VP-OT peptides on pair bonding and gregariousness; reveal previously unkno

31 mine receptor subtype-specific influences on pair bonding and how dopamine receptor activation may in

32 d with female reproductive behaviors such as pair bonding and kin recognition.

33 ng a previously undescribed role for glia in pair bonding and loss.

34 e evolution of OT's female-specific roles in pair bonding and maternal functions.

35 at OXTR binding in the presubiculum supports pair bonding and parenting behavior, potentially by medi

36 s to examine the effects of drug exposure on pair bonding and related neural circuitry.

37 overlap between the processes that underlie pair bonding and those that mediate responses to abused

38 reeding grounds is important for maintaining pair bonds and is achieved by pairs that remain together

39 mine release reflect the selective nature of pair bonds and may drive the partner- and novel-directed

40 y predicts that in species lacking long-term pair bonds and menopause, males should not exhibit a pre

41 g in general and the stability of monogamous pair bonds and offspring care in particular.

42 appear to be important for the initiation of pair bonds and parental behaviors as well as the infant'

43 are thought to represent a greater threat to pair bonds and, consequently, elicit greater jealousy.

44 tion that ASR influences multiple aspects of pair-bond and mating behavior in wild populations.

45 Unbalanced ASRs are predicted to influence pair-bond and mating behavior, since the rarer sex in th

46 Our results suggest that pair-bonding and increased sex egalitarianism in human e

47 ociation between variation in OXTR and human pair-bonding and other social behaviors, possibly indica

48 cin receptor gene (OXTR) are associated with pair-bonding and related social behaviors in humans.

49 uptake were found between males in long-term pair-bonds and lone males in areas including the nucleus

50 ences in courtship, mate competition, social pair-bonds and parental care.

51 on, (c) motivation for parental behavior and pair bonding, and (d) the neural consequences of social

52 ry for group living, selective reproduction, pair bonding, and dominance hierarchies.

53 female-specific deficits in gregariousness, pair bonding, and nest cup ownership; reduces side-by-si

54 les (Microtus ochrogaster) form opposite-sex pair bonds, and upon partner separation, show stress phe

55 ebrate taxa, focusing on female mate choice, pair-bonding, and aggressive behavior.

56 that sex-naive animals age differently from pair-bonded animals.

57 Short-term pair bonds are also associated with unbalanced ASRs: mal

58 Coordinated pair bonds are common in birds and also occur in many ot

59 rove with pair-bond duration, yet multi-year pair bonds are common, could be explained by benefits af

60 ch individuals form pairs just to mate (i.e. pair bonds are ephemeral) and later move on to sexually

61 that extended partner separation diminishes pair bond-associated behaviors and causes pair bond tran

62 ir bonding, but increase and return to a pre-pair bonded baseline after the dissolution of a pair bon

63 plicated in increased partner preference and pair bonding behavior in mammalian lineages.

64 ial problems, which longitudinally predicted pair-bonding behavior in the TCHAD sample.

65 peline to identify brain circuits underlying pair-bonding behavior.

66 1240), comprising measures of self-reported pair-bonding behavior.

67 in plays a central role in the regulation of pair-bonding behavior.

68 cus of such research, especially its role in pair bonding between mates in species that display monog

69 cially monogamous rodent that forms enduring pair bonds between adult mates.

70 g the formation and maintenance of selective pair bonds between mates.

71 of human origins is the emergence of strong pair-bonding between males and females accompanied by a

72 h levels of affiliative behaviors, including pair-bonding, biparental care, and cooperative breeding.

73 ions and beyond the mother-offspring, kin or pair bond broadens the generality of the social bufferin

74 g that PVN OT neural densities decrease with pair bonding, but increase and return to a pre-pair bond

75 ces to other divergent human traits, such as pair bonds, but our study reveals that intergroup male a

76 , potentially promoting the maintenance of a pair bond by inhibiting aggressive responses.

77 te change by pair members and/or breaking of pair bonds by unmated individuals is more frequent when

78 The formation of monogamous pair bonds, by prairie voles, is facilitated by activati

79 In the laboratory, pair bonds can be assessed by testing for a partner pref

80 chrogaster) are monogamous rodents that form pair bonds characterized by a preference for a familiar

81 We find little evidence of a "pair-bonding circuit" in Eulemur akin to those proposed

82 ogamous species in regions part of putative "pair-bonding circuits".

83 nd female prairie voles, animals were either pair bonded, co-housed with a same-sex sibling, separate

84 ominent scenarios of the human transition to pair-bonding: communal care, mate guarding, food for mat

85 (i.e., alpha-helix N conformation, DNA base pair bonding, conformation of protein residues in the vi

86 How such a transition from promiscuity to pair-bonding could be achieved is puzzling.

87 effects are observed for social preferences, pair bonding, courtship, maintenance behaviors, or anxie

88 paration erodes transcriptomic signatures of pair bonding despite core behavioral features of the bon

89 -associated gene clusters sensitive to acute pair bond disruption and loss adaptation.

90 nmentally induced changes in demographic and pair-bond disruption rates as crucial factors shaping de

91 sults highlight the pro-oncogenic effects of pair-bond disruption, point to the acquisition of expres

92 Overall, pair-bond disruptions reduced subsequent vital rates and

93 g in monogamous prairie voles, we found that pair bonding does not elicit differences in overall nucl

94 Divorce propensity declined with pair-bond duration and reproductive success in both sexe

95 l reproductive success does not improve with pair-bond duration, yet multi-year pair bonds are common

96 gitudinal relationship between precursors of pair-bonding during childhood and subsequent behavior in

97 und that environmental conditions can affect pair-bond dynamics both directly and indirectly.

98 pulations of monogamous species by affecting pair-bond dynamics.

99 rns despite similar behavioral indicators of pair-bond establishment.

100 Parrotlets are monogamous with long-term pair bonds, exhibit a strongly male-biased adult sex rat

101 Together, our data demonstrate that pair-bonding experience decreases the rewarding properti

102 s (sEPSCs) in sexually naive virgin, but not pair-bonded, female voles, while it increases the amplit

103 Hergic neurons play in regulating changes in pair bonding following social conflict.

104 Males that were pair-bonded for 2 weeks displayed intense levels of aggr

105 are mediated by neural mechanisms regulating pair bond formation and not alcohol's effects on mating,

106 cies differences in the behaviors, including pair bond formation and paternal care, found selectively

107 potential role for CART in the regulation of pair bond formation between monogamous mates and suggest

108 se data demonstrate opposing regulation over pair bond formation by cAMP signaling within the NAcc sh

109 ing that AVP in the lateral septum regulates pair bond formation in male prairie voles and that this

110 Reward mechanisms are involved in pair bond formation in monogamous prairie voles.

111 es of action for CRF-induced facilitation of pair bond formation in prairie voles, as well as potenti

112 interaction of these circuits in a model of pair bond formation in rodents with a discussion of the

113 the regulation of alloparental behavior and pair bond formation in the socially monogamous prairie v

114 ich receptors in these brain regions mediate pair bond formation in this monogamous species.

115 ntagonist in the lateral septum also blocked pair bond formation induced by either mating or AVP admi

116 tested the hypothesis that DA regulation of pair bond formation is mediated via the cAMP signaling c

117 how that dopamine transmission that promotes pair bond formation occurs within the rostral shell of t

118 the dorsomedial NAc shell appear to mediate pair bond formation through the positive hedonics associ

119 ve affiliation between adult mates, known as pair bond formation, as assessed by partner preference i

120 m in not only the impact of social defeat on pair bond formation, but also in the role BNST CRHergic

121 knowledge of central dopamine involvement in pair bond formation, expression, and maintenance.

122 posite effects: D1-like activation prevented pair bond formation, whereas D2-like activation facilita

123 of maintaining signals of quality well after pair bond formation.

124 t AVP in the lateral septum is important for pair bond formation.

125 ction, and the subsequent mating facilitates pair bond formation.

126 to investigate the impact of this stress on pair bond formation.

127 uitry during social interactions facilitates pair bond formation.

128 e distinct subregions differentially mediate pair bond formation.

129 in the NAcc, resulting in the impairment of pair bond formation.

130 gh dopamine is necessary for mammalian adult pair-bond formation and maternal behavior, its function

131 Pair-bond formation depends vitally on neuromodulatory s

132 A neurobiological model for pair-bond formation has emerged from studies in monogamo

133 the hypothesis that NAcc DA is critical for pair-bond formation in male prairie voles.

134 ogamy, as oxytocin and vasopressin influence pair-bond formation in the monogamous species.

135 Blocking CB1 receptors after pair-bond formation increases the occurrence of a specif

136 that V1aR activation in this region promotes pair-bond formation via a mechanism similar to condition

137 familiar opposite-sex partner, used to index pair-bond formation) by male voles.

138 ehaviors associated with monogamy, including pair-bond formation, are facilitated by the neuropeptide

139 icetines that differ in the extent of social pair-bond formation, Siberian (Phodopus sungorus) and Dj

140 CpGs in five genes strongly associated with pair bonding: Foxp4, Phf2, Mms22l, Foxb1, and Eif1ad.

141 that the mate-guarding hypothesis for human pair bonds gains strength from explicit links with our g

142 Voles that were pair bonded had fewer PVN OT neurons, suggesting that PV

143 a monogamous rodent that forms long-lasting pair bonds, has proven useful for the neurobiological st

144 Also, consistent with the pair bonding hypothesis of the function of romantic kiss

145 Next, we assessed how pair bonding impacts epigenetic aging.

146 eronasal organ (VNO) in estrus induction and pair bonding in female prairie voles.

147 ation of enduring aggression associated with pair bonding in male prairie voles.

148 Naderi et al. published in eLife shows that pair bonding in monogamous mice is protective against tu

149 been directly linked to the neurobiology of pair bonding in monogamous species.

150 the cognitive building blocks of monogamous pair bonding in prairie voles (Microtus ochrogaster), as

151 costerone and central CRF receptors modulate pair bonding in the monogamous prairie vole.

152 We utilized pair bonding in the socially monogamous prairie vole as

153 ssociated with the formation of opposite-sex pair bonds in microtine rodents.

154 T) receptors (OTRs) impairs the formation of pair bonds in prairie voles (Microtus ochrogaster) and z

155 be important in the maintenance of long-term pair bonds in specific environments.

156 rain play critical roles in the formation of pair bonds in the monogamous prairie vole.

157 Previous studies have related pair-bonding in Microtus ochrogaster, the prairie vole,

158 ences in the molecular mechanisms underlying pair-bonding in prairie voles and paves the way to furth

159 n OXTR was associated with traits reflecting pair-bonding in women in the TOSS and TCHAD samples.

160 ormation of partner preferences (an index of pair bonding) in female prairie voles.

161 rence (PP) formation (a laboratory proxy for pair bonding) in socially monogamous prairie voles (Micr

162 results based on assuming long-term, stable pair bonds, in which case one is capable of preventing o

163 Furthermore, pair bonding increased corticotropin-releasing hormone (

164 ypically characterized by the formation of a pair bond, increased territorial defense, and often bipa

165 Microtus ochrogaster) display mating-induced pair bonding indicated by social affiliation with their

166 ting behavior: divorce, social polygamy, and pair-bond infidelity.

167 Adult pair bonding involves dramatic changes in the perception

168 r) have shown that although formation of the pair bond is accompanied by a suite of behavioral change

169 The establishment of a pair bond is associated with a behavioral transition fro

170 in monogamous rodents at which disruption of pair bonds is linked to anxiety and stress.

171 and the subsequent development of monogamous pair-bonds is substantially predicted by influential imp

172 In monogamous species, pair bonding leads to striking changes in social behavio

173 Opposite-sex pair bonding led to changes in accumbal transcription th

174 to forgoing access to resources, maintaining pair bonds led individuals to develop a flexible "scroun

175 ovements in annual reproductive success with pair-bond length could be a secondary factor favouring p

176 ogenous opioid systems, opiate regulation of pair bond maintenance has never been studied.

177 le, male voles showed behavior indicative of pair bond maintenance-namely, selective aggression towar

178 erstanding of neural mechanisms that mediate pair bond maintenance.

179 rsive social motivation that is critical for pair bond maintenance.

180 attractive because humans maintain long-term pair bonds, making reproductive value (i.e. future repro

181 In the present study, we separated pair bonded male and female prairie voles after five day

182 Pair-bonded male prairie voles (Microtus ochrogaster) we

183 re we show that this selective aggression in pair-bonded male prairie voles is associated with increa

184 nctional MRI experiment with 20 heterosexual pair-bonded male volunteers.

185 After pair-bonding, male prairie voles (Microtus ochrogaster)

186 Twelve pair-bonded males (including six with a lesion of the pr

187 Pair-bonded males also showed an increased density in V1

188 blockade diminished selective aggression in pair-bonded males.

189 In many species that form pair bonds, males display to their mate after pair forma

190 ehavior, controlling lactation, parturition, pair bonding, maternal behavior, anxiety, and sociabilit

191 ) with the option to provide food rewards to pair-bonded mates.

192 involves significant cooperation, selective pair-bonds may develop between 2 nestmates.

193 at if early hominins had mating systems with pair-bonds (monogamous or polygynous), then food sharing

194 showed better visual acuity than that of the pair-bonding, monogamous X. flavipinnis.

195 Rodent studies have focused on pair-bonded, opposite-sex mates and suggest that a varie

196 le males and their choice is unrestricted by pair bonds or the need for biparental care, yet some fem

197 P in the regulation of aggression induced by pair-bonding or drug experience in socially monogamous m

198 scuous mating system without one-male units, pair bonds, or male parental care.

199 ith a same-sex sibling, separated from their pair bond partner, or separated from their sibling.

200 ehaviors associated with monogamy, including pair bonding, paternal care and mate guarding.

201 erence (CPP) in sexually naive (SN), but not pair-bonded (PB), males.

202 ), suggesting that the protective effects of pair bonds persisted even after bonding ceased.

203 ed through the cleavage of covalent electron-pair bonds, play an important role in diverse fields ran

204 Pair-bonded prairie voles (Microtus ochrogaster) are bip

205 It is often claimed that pair bonds preferentially form between individuals that

206 mpal OXTR in male and female titi monkeys, a pair-bonding primate species that exhibits biparental ca

207 singly few genes have been implicated in the pair-bonding process in either sex.

208 enes, networks, and pathways involved in the pair-bonding process in the nucleus accumbens, our work

209 dimorphic involvement of stress hormones in pair bonding provides a proximate mechanism for regulati

210 We show that the 002 pair bonds rapidly under a wide range of conditions and

211 ed potential epigenetic mechanisms mediating pair-bond regulation and found that the histone deacetyl

212 ially monogamous monkeys that display strong pair bonds similar to human romantic attachments, preced

213 ASR is strongly correlated with long-term pair bonds, since the divorce rate is higher in species

214 We investigated the sensitivity of jackdaws, pair-bonded social corvids that exhibit an analogous eye

215 s complex mammalian social behaviors such as pair bonding, social recognition and aggression causally

216 tioned stimulus) while potentially promoting pair-bonding, social memory and parental care.

217 on in the nucleus accumbens as a function of pair-bonding status.

218 this structure is crucial for mating-induced pair bonding, suggesting an important role for the VNO i

219 ghly social, monogamous species and displays pair bonding that can be assessed by the presence of sel

220 crotus ochrogaster), mating induces enduring pair-bonds that are initiated by partner preference form

221 Owing to its ability to form long-term pair-bonds, the socially monogamous prairie vole has eme

222 Consistent with evolutionary models of human pair bonding, these findings suggest that both consensua

223 suggest that repeated AMPH exposure impairs pair bonding through an OT-mediated mechanism, and that

224 rgument that connects the evolution of human pair bonds to the male-biased mating sex ratios that acc

225 es pair bond-associated behaviors and causes pair bond transcriptional signatures to erode.

226 For both sexes, we show that pair bonding up-regulates mRNA expression for genes enco

227 We did not find evidence that pair-bonded voles exhibit accelerated or decelerated epi

228 a partner preference, a choice test in which pair-bonded voles regularly prefer their partner to a co

229 receptor type 1 (CB1) receptor signaling in pair-bonded voles.

230 ccumbens in the formation and maintenance of pair bonds was assessed in a series of experiments using

231 ted with cognitions and behaviors related to pair bonding; we thus leveraged longitudinal data from a

232 e bonding was attributed to the reduced lone pair bond weakening effect, LPBWE, upon substitutions wi

233 sioned females failed to show mating-induced pair bonding whereas intact and sham-lesioned females di

234 cies of vole, one of which is monogamous and pair bonds whereas the other species is promiscuous and

235 in the lateral septum blocked mating-induced pair bonding, whereas administration of AVP induced this

236 Prairie vole breeder pairs form monogamous pair bonds, which are maintained through the expression

237 Divorce-terminating a pair bond whilst both members are alive-is a mating stra

238 prairie voles (Microtus ochrogaster) form a pair bond with a female partner after mating, and this b

239 es can dissolve and individuals can form new pair bonds with other conspecifics.

240 ormation of a sigma-complex through electron-paired bonding within the triplet manifold.

241 We show that pair-bonded zebra finches (Taeniopygia guttata) communic