ライフサイエンスコーパス: palmitic acid

1 regulation) but could be induced in vitro by palmitic acid.

2 obtained through the extent of diffusion of palmitic acid.

3 s may be mediated by lower triglycerides and palmitic acid.

4 er triglyceride levels and lower circulating palmitic acid.

5 lexa Fluor 647 DIBO Alkyne was conjugated to palmitic acid.

6 rived from beta-oxidation of [1,2,3,4-(13)C4]palmitic acid.

7 ydrolyzes retinyl palmitate into retinol and palmitic acid.

8 evidence for beta-oxidation of perfused M+4 palmitic acid.

9 se macrophages treated with high glucose and palmitic acid.

10 id, linoleic acid, alpha-linolenic acid, and palmitic acid.

11 oleic acid > linolenic acid > Stearic acid > Palmitic acid.

12 mice and stimulated with TLR2 ligand and/or palmitic acid.

13 r a breakfast meal that contained deuterated palmitic acid.

14 , or C20-sphing-4-enin derivative coupled to palmitic acid.

15 of toxicity palmitoleic acid > oleic acid > palmitic acid.

16 kdown McA cells incubated in MCD medium with palmitic acid.

17 by the enzymatic product of FA2H, 2-hydroxy palmitic acid.

18 rtially reversed by treatment with 2-hydroxy palmitic acid.

19 cells on conjugated linoleic acid but not on palmitic acid.

20 d with a monolayer of free base porphyrin or palmitic acid.

21 with dipalmitoylphosphatidylcholine and with palmitic acid.

22 by labeling of the protein with [3H]-labeled palmitic acid.

23 oA serve as substrates for FAS to synthesize palmitic acid.

24 recombinant OMP G1a contain covalently bound palmitic acid.

25 re each modified by the covalent addition of palmitic acid.

26 COX-2 is allosterically activated 2-fold by palmitic acid.

27 g, and cysteine and methionine metabolism by palmitic acid.

28 concentrations and more favorable ones than palmitic acid.

29 ntial in peroxisomal oxidation of lauric and palmitic acid.

30 nformational-selection, as did P450 2C8 with palmitic acid.

31 s, and less of the nutritionally-undesirable palmitic acid.

32 (MUFA), Polyunsatured Fatty Acids (PUFA) and Palmitic Acid.

33 ae) showed that NgDelta0-ELO1 could elongate palmitic acid.

34 tion of miR-30b and 378 but not by oleate or palmitic acid.

35 hospholipid fraction were oleic equally with palmitic acids.

36 ined three types of fatty acids, 0.48 microg palmitic acid, 0.61 microg stearic acid and 0.83 microg

37 ence: myristic acid 1.15 [95% CI 1.09-1.22], palmitic acid 1.26 [1.15-1.37], and stearic acid 1.06 [1

38 Metabolic labeling with alkyne-palmitic acid (100 mum for 15 h) also showed that ASBT i

39 Treatment of 2BT cells with saturated palmitic acid (100 mum for 15 h) increased ASBT function

40 similar metabolism (stearic acid: (13) C-SA; palmitic acid: (13) C-PA; oleic acid: (13) C-OA) were or

41 Changes from baseline with an LFD for palmitic acid (16:0) (3-11% increase), behenic (22:0) an

42 ha-synuclein gene-ablated mice with [1-(14)C]palmitic acid (16:0) and assessed fatty acid uptake and

43 n SFAs varying in chain length, specifically palmitic acid (16:0) and stearic acid (18:0), relative t

44 ated associations of major circulating SFAs [palmitic acid (16:0) and stearic acid (18:0)] and MUFA [

45 epidemiologic studies, circulating levels of palmitic acid (16:0) are associated with diabetes; howev

46 .10433-10434AA >GC was associated with lower palmitic acid (16:0) concentration but higher oleic (18:

47 d the hypothesis that high-fat meals rich in palmitic acid (16:0) in the sn-2 position decrease lipem

48 ic acid, oleic acid, and palmitoleic acid to palmitic acid (16:0) ratio were significantly increased

49 elations of 4 fatty acids in the DNL pathway-palmitic acid (16:0), palmitoleic acid (16:1n-7), 7-hexa

50 Palmitic acid (16:0), stearic acid (18:0), palmitoleic a

51 6:1omega-3)] and the ratio of palmitoleic to palmitic acid (16:1n-7/16:0), as an estimation of the ac

52 ains biologically important fatty acids like palmitic acid (2.06%), linolenic acid (2.56%), and oleic

53 d (2.2 wk; 95% CI: 0.8, 3.6; P = 0.002), and palmitic acid (2.9 wk; 95% CI: 1.0, 4.9; P = 0.004) per

54 he principal fatty acids in the species were palmitic acid (23.38-30.49%) and linoleic acid (20.19-29

55 C analysis for MAE cottonseed oil determined palmitic acid (23.6%), stearic acid (2.3%), oleic acid (

56 rimarily of oleic acid (33.35%), followed by palmitic acid (26.16%), stearic acid (10.07%), palmitela

57 In fact, the main fatty acids are palmitic acid (36.47-39.55%) and oleic acid (18.83-22.21

58 Major fatty acids were palmitic acid (44%) and oleic acid (46%) in ghee, while

59 6%), while the main saturated fatty acid was palmitic acid (5-29%).

60 Supplementing the HCT-8 cells with palmitic acid (80 mum), the end product of fatty acid sy

61 id (66.73%) followed by oleic acid (14.78%), palmitic acid (9.74%), and stearic acid (7.37%).

62 er position on the hydroxy fatty acid (e.g., palmitic-acid-9-hydroxy-stearic-acid, 9-PAHSA).

63 tous bound ligands, which were identified as palmitic acid (a fatty acid) and isopropyl laurate (a fa

64 results reveal mechanistic insight about how palmitic acid activates TLR2, upregulates NALP3 expressi

65 In vitro, palmitic acid alone did not increase TLR2 signaling-targ

66 Chop(+/+) and Chop(-/-) were challenged with palmitic acid, an abundant saturated free fatty acid in

67 Palmitic acid, an efficacious stimulator of human PGHS-2

68 we report the metabolic incorporation of the palmitic acid analog 17-octadecynoic acid (17-ODYA) in c

69 e residues or pretreatment of cells with the palmitic acid analog 2-bromopalmitate, reduced the [3H]p

70 ition allowed the conjugation of fatty acid (palmitic acid analog) to Uox with the HSA binding capaci

71 eld likely due to the enhanced solubility of palmitic acid analog.

72 African palm oil) with only 10-15% of total palmitic acid and 6-20% of stearic acid acylated in the

73 was found in the largest amount, followed by palmitic acid and behenic acid.

74 y are modified by the addition of N-terminal palmitic acid and C-terminal cholesterol moieties, both

75 aT cells are stimulated to express IL-17A by palmitic acid and CD1d ligation.

76 o the Western diet fat composition) to a low-palmitic acid and high-oleic acid diet (HOA; similar to

77 Branched esters of palmitic acid and hydroxystearic acid (PAHSA) are anti-i

78 recipitating PLM from ARVM loaded with [(3)H]palmitic acid and immunoblotting following streptavidin

79 In summary, both palmitic acid and linoleic acid exert inhibitory effect

80 cid profiles show significant differences in palmitic acid and long-chain fatty acids.

81 -1beta when challenged with a combination of palmitic acid and LPS or TNF-alpha.

82 s (FAs), including oleic acid, stearic acid, palmitic acid and myristic acid, were the primary chemic

83 ss than 8 nM and turnover numbers similar to palmitic acid and N-palmitoylglycine.

84 e lower after the stearic acid diet than the palmitic acid and oleic acid diets (P < 0.01).

85 ride as the major component and were rich in palmitic acid and oleic acid.

86 dothelial cells (HCAECs) incubated with both palmitic acid and oleic acid.

87 hanistic level, PLA2denat -MB containing 20% palmitic acid and PEG induced PLA2-specific IgA and incr

88 We found a positive association between palmitic acid and risk of total, localized, and low-grad

89 n this large prospective cohort, circulating palmitic acid and stearic acid were associated with high

90 At baseline, circulating palmitic acid and stearic acid were positively associate

91 y myristic acid; instead, it was acylated by palmitic acid and stearic acid.

92 fatty acids, and caveolin-1 was acylated by palmitic acid and stearic acid.

93 sphocholine resulted in the rapid release of palmitic acid and the selective accumulation of 2-arachi

94 Compared with fresh fish samples, palmitic acid and tocopherol content decreased in a 20%

95 (pentacosane and heptacosane), fatty acids (palmitic acid and trans-vaccenic acid), and cholesterol;

96 Here, we confirm that saturated (e.g. palmitic acid) and unsaturated (e.g. docosahexaenoic aci

97 dia supplemented with 28 mM glucose, 200 muM palmitic acid, and 200 muM oleic acid as a cellular mode

98 migration, and tube formation in response to palmitic acid, and a potential target for therapies trea

99 Organoids were incubated with oleic and palmitic acid, and formation of lipid droplets was visua

100 ly by Oil Red O staining in cells exposed to palmitic acid, and it was accompanied by an increase in

101 low concentrations of gamma-linolenic acid, palmitic acid, and long-chain monounsaturated fatty acid

102 e damage than other free fatty acids such as palmitic acid, and mediates selective loss of intrahepat

103 acids, gamma-linolenic acid, linoleic acid, palmitic acid, and oleic acid.

104 114 solubilization, radiolabeling with [(3)H]palmitic acid, and sucrose density gradient membrane par

105 t FR milk had less saturated FA (SFA) and/or palmitic acid, and/or greater alpha-linolenic and rumeni

106 t were measured (14:0 [myristic acid], 16:0 [palmitic acid], and 18:0 [stearic acid]) were positively

107 inhibited Akt-mediated eNOS phosphorylation, palmitic acid appeared to affect the upstream signaling.

108 Here we show that both TLR2 and palmitic acid are required for activation of the inflamm

109 -fat diets, specifically those enriched with palmitic acid, are CNS mediated via PKC-theta activation

110 y lutein esters esterified with myristic and palmitic acid as monoesters or diesters, were found.

111 hases within both leaflets was obtained with palmitic acid as the anchoring group.

112 majority of alpha-retinol was esterified to palmitic acid (as compared with other fatty acids).alpha

113 This finding was specific for palmitic acid, as the monounsaturated fatty acid, oleic

114 ference for choline phospholipids containing palmitic acid at the sn-1 position that could be exploit

115 Adjustment for triglycerides and palmitic acid attenuated the associations toward the nul

116 content of linoleic acid and high content of palmitic acid behaved exceptionally well.

117 Non-substrate FAs like palmitic acid bind Eallo of PGHSs stimulating human (hu)

118 The [(3)H]palmitic acid binds to the coated phospholipid through h

119 ids present in Liposyn II, linoleic acid and palmitic acid, both reduced proliferation.

120 Further, MCD medium with palmitic acid, but not oleic or linoleic acids, maximall

121 process initiated at the elongation step of palmitic acid by Delta0-ELO1, thus acting as a committin

122 s a mixture of saturated and monounsaturated palmitic acid (C(16)).

123 rns of (R)-tuberculostearic acid (C19:0) and palmitic acid (C16:0) and their mass spectral characteri

124 interspecific hybrids is known to have lower palmitic acid (C16:0) content compared to pure African p

125 We examined 8 species: Cer and SM with palmitic acid (Cer-16 and SM-16), species with arachidic

126 These results demonstrate that a palmitic acid-ceramide pathway accounts for impaired int

127 the (2)H NMR order parameter profile of the palmitic acid chain in POPC.

128 Palmitic acid, chosen as the case study of single fatty

129 etabolites, including malonyl-coenzyme A and palmitic acid, completely restored the inhibitory effect

130 of L. interrogans in medium containing [14C]palmitic acid, confirming that it is a lipoprotein.

131 As a proof-of-concept, we show that single palmitic acid conjugated to superfolder green fluorescen

132 Administration of palmitic acid-conjugated ASO (Palm-ASO) in mice results

133 Palmitic acid conjugation increases ASO plasma Cmax and

134 TLR2 and palmitic acid cooperatively activate the inflammasome in

135 13)C-glucose, U-(13)C-glutamine, and U-(13)C-palmitic acid) demonstrated enhanced oxidative metabolis

136 TO901317 also shifted palmitic acid-derived FFAs into biologically inactive tr

137 In the presence of TLR2 ligand, palmitic acid did induce caspase-1 activation and releas

138 e stearic acid and oleic acid diets than the palmitic acid diet (all P < 0.01).

139 , crossover trials that compared a 3-wk high-palmitic acid diet (HPA; similar to the Western diet fat

140 sent multiple lines of evidence showing that palmitic acid directly activates TLR2, a major TLR expre

141 Here, we synthesized the R- and S- palmitic acid ester of 9-hydroxystearic acid (R-9-PAHSA,

142 Specifically, CHO-containing OxPCs with palmitic acid esterified to the sn-1 position of the gly

143 Palmitic acid esters of hydroxy stearic acids (PAHSAs) a

144 Palmitic acid esters of hydroxy stearic acids (PAHSAs) a

145 Palmitic acid esters of hydroxy stearic acids (PAHSAs) a

146 y novel class of endogenous lipids, branched palmitic acid esters of hydroxy stearic acids (PAHSAs),

147 6 different FAHFA families, such as branched palmitic acid esters of hydroxy stearic acids (PAHSAs);

148 Palmitic acid esters of hydroxy-stearic acids (PAHSAs) a

149 This solvent has an efficiency of palmitic acid extraction of 34.14%, and the amount of an

150 h adjustment for demographics and lifestyle, palmitic acid (extreme-quintile HR: 1.89; 95% CI: 1.27,

151 , the enzyme that catalyzes the formation of palmitic acid from malonyl-CoA, drove NF2-deficient cell

152 unt of 2-DCB formed from the model compounds palmitic acid, glyceryl tripalmitate and 1,3-dipalmitoyl

153 ffect decreased in the sequence oleic acid > palmitic acid > myristic acid > linoleic acid > linoleni

154 nd that coating the particles with insoluble palmitic acid had little effect on the deliquescence, ef

155 Conjugation of palmitic acid improved potency of DMPK, Cav3, CD36 and M

156 ified by a fatty acid anchor on Cys-9 with a palmitic acid in about 60% and, surprisingly, an oleic a

157 al cognitive decline increased with elevated palmitic acid in both fractions and with high arachidoni

158 significantly reduced ROS levels induced by palmitic acid in human aortic endothelial cells.

159 fectively prevent oxidation damage caused by palmitic acid in insulinoma cells.

160 mpletely inhibited the induction of MCP-1 by palmitic acid in mesangial cells.

161 are similar, except for a small increase in palmitic acid in plastoglobuli, suggesting a common orig

162 nous upregulation of C(16:0)-Cer mediated by palmitic acid in RAW 264.7 macrophages led to a signific

163 acids with glycine and the high abundance of palmitic acid in the brain, we hypothesized the endogeno

164 ort chain acyl-CoAs, palmitoylcarnitine, and palmitic acid in the presence of CoASH were without effe

165 Fats with a higher proportion of palmitic acid in the sn-2 position decrease postprandial

166 LSFAs), with 20 or more carbons, differ from palmitic acid in their biological activities, and little

167 of excess d-glucose, "saturated cypate" and palmitic acid in two normal-cancer cell line pairs: lung

168 cid analog 2-bromopalmitate, reduced the [3H]palmitic acid incorporation into CD44 and prevented CD44

169 Palmitic acid incorporation kinetics indicated that, at

170 Culture of AML12 hepatocytes with palmitic acid increased cytotoxicity through apoptosis a

171 ncreased in aggressive HCCs; monounsaturated palmitic acid increased migration and invasion of cultur

172 vity led to decreased PTEN expression, while palmitic acid increased PTEN in myotubes in a p38-depend

173 covered that enhancing S-palmitoylation with palmitic acid increases Nav1.6 current, whereas blocking

174 on of autophagy by chloroquine (CQ) enhanced palmitic acid-induced apoptosis accompanied by increased

175 ed generation of ROS was associated with the palmitic acid-induced autophagy in podocytes.

176 expression in cultured podocytes and reduced palmitic acid-induced cell death.

177 imilarly, overexpression of Scd-1 attenuated palmitic acid-induced cell death.

178 ll interfering RNA knockdown of RIP3 reduced palmitic acid-induced cytotoxicity.

179 This study characterizes palmitic acid-induced lipotoxicity (PA-LTx) in Schwann c

180 We showed that palmitic acid-induced oxidative stress caused conjugatio

181 yoblasts, silencing of cathepsin K inhibited palmitic acid-induced release of cytochrome c from mitoc

182 agy by rapamycin (Rap) remarkably suppressed palmitic acid-induced ROS generation and apoptosis.

183 Moreover, lipopolysaccharide or palmitic acid-induced TLR4 activation and high glucose f

184 Palmitic acid induces CRNDE expression by 1.9-fold.

185 Palmitic acid inhibits insulin signaling by promoting PT

186 abolic incorporation of an alkynyl analog of palmitic acid into cellular proteins coupled with click

187 -translational protein modification in which palmitic acid is added to cysteine residues, allowing as

188 In these experiments, the palmitic acid is delivered as a complex with delipidated

189 dodecanoic acid, L-methionine, hypoxanthine, palmitic acid, L-tryptophan, kynurenic acid, taurine, an

190 In this study, we demonstrate using [(3)H]palmitic acid labeling and acyl-biotinyl exchange that n

191 [(3)H]palmitic acid labeling demonstrated that both native and

192 Conversely, [(13)C(16)]-palmitic acid labeling demonstrated that GCBCs generate

193 The synthesis of glucose esters with palmitic acid, lauric acid and hexanoic acid using lipas

194 residual peroxisomal oxidation of lauric and palmitic acid, leading to the production of peroxisomal

195 Activation of TLR2 by palmitic acid leads to expression of pro-IL-1beta that i

196 Gsp sensing, such as refined cottonseed oil, palmitic acid, linoleic acid, and alpha-tocopherol, did

197 ead separation and incubated with or without palmitic acid, LPS, or TNF-alpha for 24 hours, and IL-1b

198 at hearts were perfused with [1,2,3,4-(13)C4]palmitic acid (M+4), and the isotopic patterns of myocar

199 This study also suggests that SFA palmitic acid may play an important role in MetS-associa

200 chromosome 10) activity and transcription by palmitic acid mediated the inhibitory effects on insulin

201 trometry identified 2 saturated fatty acids, palmitic acid methyl ester (PAME) and stearic acid methy

202 hiphilic drug formulation additives based on palmitic acid-modified poly(ethylene glycol) (Pal-PEG) a

203 d from HSV-1 gD, were covalently linked to a palmitic acid moiety (lipopeptides) and delivered subcut

204 lator of human PGHS-2, binds only E(allo) in palmitic acid/murine PGHS-2 co-crystals.

205 t, respectively), and for few individual FA (palmitic acid, oleic acid), having R(CV)(2) higher than

206 fore characterized S-acylation event linking palmitic acid, oleic acid, and stearic acid at C78 of th

207 ficient values indicated higher measures for palmitic acid, oleic acid, unsaturated and monounsaturat

208 Total hepatic FA profiling revealed a higher palmitic acid/oleic acid (PA/OA) ratio in WT mice, compa

209 The reversible thioester linkage of palmitic acid on cysteines, known as protein S-palmitoyl

210 analogue partially reproduces the effects of palmitic acid on insulin signaling.

211 s effects of diets high in fat, specifically palmitic acid, on hypothalamic insulin activity in rats

212 We show that palmitic acid or palm oil increases ceramide production

213 acid, whereas it is decreased in response to palmitic acid or triglycerides.

214 Incubation of lauric acid, palmitic acid, or oleic acid (OA) with human sebocytes d

215 immune cells stimulated with the fatty acid, palmitic acid, or with lipopolysaccharide.

216 data show that the saturated fatty acid (FA) palmitic acid (PA) activates the inflammasome and induce

217 n this study we sought to examine effects of palmitic acid (PA) and oleic acid, two of the common die

218 r these studies, both saturated fatty acids (palmitic acid (PA) and stearic acid (SA)) and unsaturate

219 -sensitizing properties, is synthesized from palmitic acid (PA) catalyzed by stearoyl-coenzyme A desa

220 The levels of saturated palmitic acid (PA) from most of the tested seed oils wer

221 Accumulation of palmitic acid (PA) in cells from nonadipose tissues is k

222 carboxylic acid of atmospherically relevant palmitic acid (PA) is accompanied by binding of the Mg(2

223 of the lung-surfactant peptide SP-B1-25 in a palmitic acid (PA) monolayer.

224 In the present study, we demonstrated that palmitic acid (PA) promoted autophagy in podocytes.

225 as suggested that diets with a high ratio of palmitic acid (PA) to oleic acid (OA) increase risk of c

226 h PKR after induction of metabolic stress by palmitic acid (PA) treatment.

227 omplex of bovine beta-lactoglobulin (Lg) and palmitic acid (PA), (Lg + PA)(n-) --> Lg(n-) + PA, at th

228 AP-1 pathways in response to treatment with palmitic acid (PA), a FFA.

229 ma nonesterified fatty acids discovered that palmitic acid (PA), a natural peroxisome proliferator-ac

230 Relative to diets enriched in palmitic acid (PA), diets rich in oleic acid (OA) are as

231 ated effects of a saturated free fatty acid, palmitic acid (PA), on endothelial cell responses to VEG

232 (DHA), relative to the saturated fatty acid palmitic acid (PA), on the hepatic expression of apo A-I

233 phagosomes), with abundant engulfed cargo in palmitic acid (PA)- or glucose-treated cells, indicating

234 andomly divided in groups and subjected to a palmitic acid (PA)- or oleic acid (OA)-enriched high-fat

235 We have shown that palmitic acid (PA)-induced lipotoxicity (PA-LTx) in nerv

236 c acid (OA) is oxidized more rapidly than is palmitic acid (PA).

237 were provided by the investigators, and the palmitic acid (PA):oleic acid (OA) ratio was manipulated

238 oselinic acid, linoleic acid, myristic acid, palmitic acid, palmitoleic acid and the deoxycholate/cho

239 leation on internally mixed ammonium sulfate/palmitic acid particles, namely optical microscopy coupl

240 re cis-palmitoleic acid (pulp) and oleic and palmitic acid (peel).

241 sess a hydrophobic cavity to bind copurified palmitic acid (PLM).

242 rthermore, characteristic fatty acids (e.g., palmitic acid), quinolone signal, and riboflavin fragmen

243 Serum stearic acid/palmitic acid ratio as a potential predictor of diabetes

244 Treatment of KO hepatocytes with palmitic acid reduced cell viability and increased apopt

245 Binding of palmitic acid renders these regulators incapable of inte

246 Among them, palmitic acid resulted the most abundant, followed by om

247 that treatment with the saturated fatty acid palmitic acid results in sustained JNK activation and in

248 RYGB, we found higher baseline stearic acid/palmitic acid (S/P) ratio.

249 id (OA/SA), and lower levels of stearic acid/palmitic acid (SA/PA) and arachidonic acid/dihomo-gamma-

250 An endogenous ligand, possibly palmitic acid, serves to illuminate the mode and mechani

251 Palmitic acid showed the lower concentration in all expe

252 rocarbon chains, and with replacement of the palmitic acid sn-1 chains by oleic acid.

253 relative comparability of diets enriched in palmitic acid, stearic acid, and oleic acid on inflammat

254 tein, 30%E fat, with ~50% fat contributed by palmitic acid, stearic acid, or oleic acid in each diet;

255 Moreover, in isolated macrophages, palmitic acid stimulated cyclooxygenase-2 induction and

256 , only myristic acid, and to a lesser extent palmitic acid, stimulated eNOS.

257 These decreases are synergistic under palmitic acid stress.

258 Similar to that in the kFABP-palmitic acid structure, the acid moiety in 1 is proxima

259 1-stearoylglycerol, 1-palmitoylglycerol, and palmitic acid, suggesting that the high serum alpha-feto

260 d in melanoma tumor nodules by PET using the palmitic acid surrogate tracer 14(R,S)-18F-fluoro-6-thia

261 alkanes and aromatic acid derivatives, being palmitic acid, tetracosanol and octacosanol the most abu

262 The equation x = 0.02t(0.5) was obtained for palmitic acid that could be used to find its position in

263 is used in the ACC/FAS coupled system, [(3)H]palmitic acid, the final product, is readily detected by

264 were treated with the saturated fatty acid, palmitic acid, the insulin-signaling pathway was impaire

265 However, evidence that palmitic acid, the major dietary saturated fatty acid, c

266 Levels of monounsaturated palmitic acid, the product of SCD activity, were increas

267 flammation, our in vitro studies showed that palmitic acid-the most abundant saturated fatty acid (SF

268 ganic acids (malonic, glutaric, azelaic, and palmitic acids), three saccharides (glucose, sucrose, an

269 d by introducing MC fatty acids with reduced palmitic acid through lipase acidolysis.

270 re given an intravenous infusion of [(2)H(2)]palmitic acid to investigate systemic nonesterified fatt

271 re also fed a mixed meal containing [U-(13)C]palmitic acid to investigate the contribution of dietary

272 hophysiologically relevant concentrations of palmitic acid to simulate the excessive influx of fatty

273 ceramide synthesis improves the response of palmitic acid-treated Caco-2/TC7 enterocytes to insulin.

274 Where palmitic acid treatment activated Chop(+/+) and Chop(-/-

275 In the latter, palmitic acid treatment inhibits glucose-induced insulin

276 n endothelial cells in response to excessive palmitic acid treatment, an obesity-like condition.

277 ll-like receptor signaling as enriched after palmitic acid treatment.

278 ressed by high-fat diet feeding and in vitro palmitic acid treatment.

279 to the PTEN promoter, which was increased by palmitic acid treatment.

280 duction, whereas the formulation bearing 80% palmitic acid triggered the production of IFN-gamma, IgG

281 RNA sequencing, flow cytometry, 3H-labeled palmitic acid uptake, lipidomic analysis, confocal and e

282 pared to their mother, whereas galactose and palmitic acid utilization were similar.

283 CNS exposure to palmitic acid via direct infusion or by oral gavage incr

284 uintile compared with the lowest quintile of palmitic acid was 1.47 (95% CI: 0.97, 2.23; P for trend

285 Importantly, palmitic acid was found to induce significantly elevated

286 The highest palmitic acid was observed in the oil obtained from untr

287 Palmitic acid was predominant in 79% of biscuits and rep

288 Palmitic acid was prevalent among the saturated fatty ac

289 the same TAG molecule together with C18 FAs, palmitic acid was typically in the sn-2 position.

290 bacterial growth when phosphatidylcholine or palmitic acid was used as the sole carbon source.

291 Interestingly, when [(3)H]palmitic acid was used as the substrate for incorporatio

292 efects in macrophage phagocytosis induced by palmitic acid were mimicked by PGE2 and PGD2 and were re

293 Higher amount of oleic, linoleic and palmitic acids were observed in olive oils.

294 cally inhibited up to 50% by common FAs like palmitic acid, whereas COX-2 is allosterically activated

295 NL of 254, 2 u less than the nominal mass of palmitic acid, whereas the analogous terminal COOH-conta

296 nd introduced close to the carboxyl group of palmitic acid, which is specifically esterified to the s

297 bundant fatty acids were linoleic, oleic and palmitic acid, while PUFA was the most abundant fatty ac

298 xis was found to be particularly enriched in palmitic acid, while the seed coat/aleurone layer accumu

299 metabolic and molecular effects of replacing palmitic acid with oleic acid; evidence for a dose-respo

300 ydomonas cells with per-deuterated D31-16:0 (palmitic) acid yielded D31-18:0 (stearic) acid, D29-18:1