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1 psoriasis," "pustular," "skin," "rash," and "palmoplantar." All relevant articles in English were rev
2 he protein expression levels of DKK1 between palmoplantar and non-palmoplantar areas and the effects
4 can cause Olmsted syndrome characterized by palmoplantar and periorificial keratoderma, itch, and ha
7 ffering types of psoriasis (plaque, guttate, palmoplantar, and late-onset), which excluded the possib
9 levels of DKK1 between palmoplantar and non-palmoplantar areas and the effects of DKK1 on melanocyte
10 apping skin disorders: multiple self-healing palmoplantar carcinoma (MSPC) and familial keratosis lic
11 verlap exists between different inflammatory palmoplantar diseases that supersedes clinical and histo
13 idermolytic palmoplantar keratoderma (PPK or palmoplantar ectodermal dysplasia type III) is associate
15 We demonstrate here a role for AQP5 in the palmoplantar epidermis and propose that the altered AQP5
16 hanisms underlying hyperproliferation of the palmoplantar epidermis in both physiological and disease
18 protein which is predominantly expressed in palmoplantar epidermis is implicated in AD may shed new
19 ferentiation, and help explain why DKK1-rich palmoplantar epidermis is paler than non-palmoplantar ep
20 ich palmoplantar epidermis is paler than non-palmoplantar epidermis via mesenchymal-epithelial intera
21 clusively in the suprabasal keratinocytes of palmoplantar epidermis, have previously been demonstrate
22 focal epidermolysis in the spinous layer of palmoplantar epidermis, in comparison with cases of bull
23 riate keratoderma particularly affecting the palmoplantar epidermis, woolly hair and a dilated left v
27 anges, with conjunctival injection (n = 21), palmoplantar erythema (n = 18), lip hyperemia (n = 17),
33 ual facies, dental anomalies, hypotrichosis, palmoplantar hyperkeratosis and onychodysplasia, syndact
34 f life, affected individuals later developed palmoplantar hyperkeratosis with patchy erythema and sca
40 For example, the transcriptome of in vivo palmoplantar (i.e., volar) epidermis is globally unique,
49 (PC, OMIM:167200) or focal non-epidermolytic palmoplantar keratoderma (FNEPPK, OMIM:613000), which ea
50 ified KRT6C mutations in patients with focal palmoplantar keratoderma (FPPK), but debate concerning o
51 ophageal cancer (TOC), and non-epidermolytic palmoplantar keratoderma (NEPPK); increased iRhom2 cleav
54 desmoglein (DSG) 1, cause the skin diseases palmoplantar keratoderma (PPK) and severe dermatitis, mu
57 delG in the V2 domain of keratin 5), striate palmoplantar keratoderma (PPK), and ichthyosis hystrix C
58 in SLURP1 lead to a rare autosomal recessive palmoplantar keratoderma (PPK), Mal de Meleda (MdM), whi
62 a dominantly inherited skin disease, striate palmoplantar keratoderma (SPPK), mapping to chromosome 1
65 characterize three Cx43 mutations linked to palmoplantar keratoderma and congenital alopecia-1, eryt
66 autosomal recessive pattern, manifests with palmoplantar keratoderma and early, destructive periodon
67 ause a dominant Mendelian disorder featuring palmoplantar keratoderma and lamellar ichthyosis, a phen
68 olidify a link between Slurp2 deficiency and palmoplantar keratoderma and to be confident that the di
69 eratitis-ichthyosis-deafness (KID) syndrome, palmoplantar keratoderma associated with hearing loss, a
70 paper, we report three patients with severe palmoplantar keratoderma associated with ichthyosis and
71 ed patients and affected family members with palmoplantar keratoderma between September 1, 2016, and
72 h mild skin fragility, woolly hair, and mild palmoplantar keratoderma but without a cardiac phenotype
75 d, scaly skin at birth, experience worsening palmoplantar keratoderma in childhood, and develop hundr
76 msted syndrome with severe periorificial and palmoplantar keratoderma in multiple unrelated kindreds.
80 Autosomal-dominant diffuse nonepidermolytic palmoplantar keratoderma is characterized by the adoptio
81 8 years or older either newly diagnosed with palmoplantar keratoderma or being followed up for the di
83 smoplakin mutation in a proband with striate palmoplantar keratoderma that also results in a null all
84 abrogated by a mutation that causes punctate palmoplantar keratoderma type 1 (PPKP1), a human skin di
89 osis on the volar surface of the paws (i.e., palmoplantar keratoderma), increased keratinocyte prolif
90 the K9 gene are known to cause epidermolytic palmoplantar keratoderma, a rare dominant-negative skin
93 n that presents with nail dystrophy, painful palmoplantar keratoderma, and other clinical manifestati
95 inant skin disease, diffuse nonepidermolytic palmoplantar keratoderma, and was investigated as a poss
96 s for the triad of autosomal recessive ARVC, palmoplantar keratoderma, and woolly hair (Naxos disease
97 gene that results in skin fragility, diffuse palmoplantar keratoderma, and woolly hair with no sympto
99 s leading to keratinopathies such as striate palmoplantar keratoderma, as reported in this study.
100 of the autosomal dominant disorder, striate palmoplantar keratoderma, as well as an autosomal recess
101 ermatosis characterized by focal and diffuse palmoplantar keratoderma, hyperkeratotic plaques on the
102 prised nail dystrophy or nail loss, marginal palmoplantar keratoderma, hypodontia, enamel hypoplasia,
103 bilateral hearing loss, blinding keratitis, palmoplantar keratoderma, ichthyosiform erythroderma and
104 epidermolysis bullosa simplex, epidermolytic palmoplantar keratoderma, junctional epidermolysis bullo
105 characterized by sensorineural hearing loss, palmoplantar keratoderma, knuckle pads, and leukonychia,
107 ensive mucocutaneous blisters, epidermolytic palmoplantar keratoderma, nail dystrophy, enamel dysplas
109 in silico panel containing genes related to palmoplantar keratoderma, or by Sanger sequencing for sp
110 autosomal-dominant syndrome characterized by palmoplantar keratoderma, oral precursor lesions, and a
111 l for pachyonychia congenita (PC)-associated palmoplantar keratoderma, prompted us to examine the rol
112 with AAGAB variants presented with punctate palmoplantar keratoderma, showing a clear genotype-pheno
124 recapitulated the clinical features of human palmoplantar keratoderma: overcornification and thickeni
127 roup of disorders, known collectively as the palmoplantar keratodermas, are unified by the phenotypic
131 nce of cardiac dysfunction or fibroadiposis, palmoplantar keratosis, and alopecia, resembling the hum
136 involved 21 adults with PPP (11 patients) or palmoplantar plaque psoriasis with pustules (10 patients
138 d be an appealing approach for treating PPP, palmoplantar plaque psoriasis with pustules, and SAPHO s
140 r pustular psoriasis (PPPP) and non-pustular palmoplantar psoriasis (NPPP) are localized, debilitatin
141 difficult to differentiate from non-pustular palmoplantar psoriasis (palmPP) and dyshidrotic palmopla
142 was reported in 68.1% (n = 28), clearance of palmoplantar psoriasis was reported in 90.0% (n = 10), c
144 er, this was not the case when patients with palmoplantar pustular psoriasis were not included in the
145 ns including generalized pustular psoriasis, palmoplantar pustular psoriasis, acrodermatitis continua
146 mutations were identified in both localized (palmoplantar pustular psoriasis, acrodermatitis continua
153 d nonlesional skin from patients with GPP or palmoplantar pustulosis (PPP) with skin from healthy vol
154 rders: generalized pustular psoriasis (GPP), palmoplantar pustulosis (PPP), and acute generalized exa
155 nical data from 125 patients with AGEP, GPP, palmoplantar pustulosis (PPP), plaque psoriasis (PSO), a
156 tular psoriasis [GPP]) or chronic localized (palmoplantar pustulosis [PPP] and acrodermatitis continu
157 30.6%; eczema, 23.5%; xerosis cutis, 10.6%; palmoplantar pustulosis, 5.3%; psoriasis, 3.8%; other, 2
158 onpustular psoriasis, 127 patients developed palmoplantar pustulosis, and 12 patients developed gener
159 atopic dermatitis, Mal de Meleda, vitiligo, palmoplantar pustulosis, and pemphigus may be mediated,
161 ermis elicits the hypopigmented phenotype of palmoplantar skin due to suppression of melanocyte funct
162 icroarray analysis, fibroblasts derived from palmoplantar skin expressed high levels of dickkopf 1 (D
164 l innervation and substantial alterations in palmoplantar skin immune composition in Slurp2X knock-ou
167 Subsequently, iRhom2 was found to affect palmoplantar thickening to modulate the stress keratin r
168 h oesophageal cancer (TOC), characterized by palmoplantar thickening, upregulate K16 with robust down
169 lar) skin of amputees to pressure-responsive palmoplantar (volar) skin to enhance prosthesis use and