ライフサイエンスコーパス: pancreas

1 on cancers (e.g., liver, colorectal, breast, pancreas).

2 h a 120-min dynamic PET scan centered on the pancreas.

3 abnormalities in the hepatobiliary system or pancreas.

4 including those of the breast, prostate, and pancreas.

5 always results in a lethal situation for the pancreas.

6 Tregs) and maintains immune tolerance in the pancreas.

7 intolerance and that Pg translocates to the pancreas.

8 termine drug uptake in tumors growing in the pancreas.

9 nant and malignant conditions related to the pancreas.

10 omeostatic and inflammatory processes of the pancreas.

11 polysynaptically connected to the liver and pancreas.

12 e major pancreatic ducts (MPDs) of the human pancreas.

13 relative to the same cells isolated from the pancreas.

14 MRF at 1.5 T and 3 T was demonstrated in the pancreas.

15 the cause of his symptoms and to assess the pancreas.

16 eneration/developmental studies in the human pancreas.

17 expressed no detectable CTRL protein in the pancreas.

18 ys, brain, heart, intestines, fat tissue and pancreas.

19 ive progenitor-like populations in the adult pancreas.

20 esults from destruction of beta cells in the pancreas.

21 e tumors in the liver, kidney, prostate, and pancreas.

22 and migration into lymphoid tissues and the pancreas.

23 ja1 restores beta-cell expansion in the aged pancreas.

24 adipose tissues including liver, muscle, and pancreas.

25 ue homeostasis in the neoplastic and injured pancreas.

26 y network between the endocrine and exocrine pancreas.

27 ggest MEN1 may also function in the exocrine pancreas.

28 d levels of tissue repair in the human donor pancreas.

29 gan systems including gut, liver, heart, and pancreas.

30 , such as adipose tissue, muscle, liver, and pancreas.

31 mSv/MBq, with the highest organ dose to the pancreas (0.274 +/- 0.099 mSv/MBq).

32 , 14.9-33.4]; 3 h: 28.2 [95%CI, 16.5-40.0]), pancreas (1 h: 42.4 [95%CI, 12.3-72.5]; 3 h: 41.1 [95%CI

33 0.3 +/- 2.2 and 22.5 +/- 1.6, respectively), pancreas (12.2 +/- 0.8 and 9.5 +/- 0.7, respectively), a

34 09-1.12), with highest HRs for liver (3.31), pancreas (2.19) and uterine cancer (1.78).

35 s (kidney 5 years: 76.5% vs 82.3%, P < 0.01; pancreas 5 years: 72.2% vs 76.3%, P = 0.01; respectively

36 We identified 110 kidney, 67 liver, 85 pancreas, 68 heart, and 43 lung TRRs.

37 rs were included: 318 (66%) kidney or kidney/pancreas, 73 (15.1%) liver, 57 (11.8%) heart, and 30 (6.

38 US cohort (kidney: 91.5% vs 87.9%, P = 0.11; pancreas: 87.4% vs 81.3%; P = 0.04, respectively) and pe

39 al-origin deconjugase (rat serum and chicken pancreas) (AE-LC-MS/MS) was used in the LC-MS/MS methods

40 -ghrelin (AG), which is also produced in the pancreas, affects beta-cell function, with particular at

41 donor kidney transplant, and the third had a pancreas after kidney transplant (PAK).

42 are of the possibility of acute and cGVHD in pancreas after kidney transplant recipients and be able

43 of possible cGVHD occurring in recipients of pancreas after kidney transplantation, which were diagno

44 e digestive enzyme chymotrypsin protects the pancreas against pancreatitis by reducing harmful trypsi

45 s protease activity and thereby protects the pancreas against unwanted SPINK1 degradation.

46 dence interval (95% CI) 0.35-0.97, P = 0.04; pancreas aHR: 0.54, 95% CI 0.34-0.85, P = 0.01].

47 The 2014 pancreas allocation system (PAS) intended to decrease ge

48 BMP/SMAD signaling is activated in protocol pancreas allograft biopsies from recipients on tacrolimu

49 Among SPK recipients, 6% had pancreas allograft failure within 3 months (SPK,P-) and

50 were actively followed and had a functional pancreas allograft for >25 years as of October 31, 2018.

51 oncocytic papillary neoplasms (IOPNs) of the pancreas and bile duct contain epithelial cells with num

52 macropinocytic, but not non-macropinocytic, pancreas and breast cancer cells resistant to these trea

53 mechanisms for cardiovascular malformations, pancreas and diaphragm dysgenesis that arise in patients

54 onstrated similar genetic profiles in normal pancreas and early clinical stage primary INS, whereas l

55 uding the lungs, spleen, liver, lymph nodes, pancreas and extrahepatic bile duct with potential for r

56 tch ligands play specific roles in the adult pancreas and highlight a novel function of the Delta/Not

57 cipating at the Ninth International European Pancreas and Islet Transplant Association (EPITA) Worksh

58 is the predominant neoplastic disease of the pancreas and it represents the fourth most frequent caus

59 bility in listing practices for simultaneous pancreas and kidney (SPK) transplant and define eligibil

60 The first simultaneous pancreas and kidney (SPK) transplant was performed in 19

61 he investigational arm died with functioning pancreas and kidney grafts.

62 ntal regulatory gene can generate xenogeneic pancreas and kidney(1,2).

63 hal effects on growth, yolk utilization, and pancreas and liver development.

64 e detected virus in systemic tissues such as pancreas and liver just 20 min after oral inoculation.

65 t fraction (%) in regions of interest in the pancreas and liver.

66 derlying these divergent T cell responses in pancreas and lung cancer are differences in infiltrating

67 Normal canine pancreas and lymph node control tissues were compared wi

68 iverticula are usually asymptomatic, annular pancreas and malrotation may manifest in the first decad

69 PD-L1 platelets) accumulate in the inflamed pancreas and may suppress the activity of pancreas autor

70 Insulin is a peptide secreted by the pancreas and plays an important role in the regulation o

71 e differences in immune response in lung and pancreas and potential approaches to overcome immunoresi

72 expressed in human PDAC compared with normal pancreas and present on both tumor and immune cells.

73 sue-compartment models were used to estimate pancreas and spleen distribution volume.

74 drawn in multiple solid organs including the pancreas and T(1) and T(2) values determined.

75 s, with the main exceptions of cancer of the pancreas and uterus, and multiple myeloma.

76 Six cancer cell lines (breast, prostate, and pancreas) and a mouse model of the mammary tumor were em

77 changes in the trachea, large intestine, and pancreas, and abnormalities in the development of the ma

78 rder, pancreas border with tumor, nontumoral pancreas, and aorta were recorded on pancreatic parenchy

79 Inflammatory factors in the serum and pancreas, and immune populations in the spleen of mice w

80 is novel infection among heart, lung, liver, pancreas, and kidney transplant recipients.

81 of multipotent progenitors in the developing pancreas, and loss of Dll1 leads to premature endocrine

82 sociated with cancers of the uterus, kidney, pancreas, and lung.

83 creatic cancer tissues and cells with normal pancreas, and measured levels of CDH11 protein in human

84 tion in the kidney, insulin secretion in the pancreas, and skeletal muscle function.

85 rtions, we studied adenocarcinomas of colon, pancreas, and stomach, and found a variable number of so

86 angiogenesis and beta-cell expansion in the pancreas are coupled by a distinct age-dependent subset

87 the insulin-producing beta cells within the pancreas are destroyed.

88 SCNs of the pancreas are invariably benign entities.

89 ence with complex cancer operations near the pancreas are similar to PD outcomes at hospitals with hi

90 nks both endocrine and exocrine parts of the pancreas as a single organ through the integrated vascul

91 by hormone-secreting endocrine cells in the pancreas, as well as glucose utilization and production

92 Adenosquamous cancer of the pancreas (ASCP) is a subtype of pancreatic cancer that h

93 gap, we investigated fetal and neonatal pig pancreas at multiple, crucial developmental stages using

94 ed pancreas and may suppress the activity of pancreas autoreactive T cells in newly hyperglycemic non

95 In the pancreas, BB-Cl-amidine treatment preserved insulin prod

96 n RFX6 c.1129C>T, which revealed loss of the pancreas body and tail.

97 ons of interest in tumor core, tumor border, pancreas border with tumor, nontumoral pancreas, and aor

98 e colorectum, esophagus, liver, lung, ovary, pancreas, breast, or stomach.

99 gen and more edema, infiltration of lung and pancreas by inflammatory cells, and plasma amylase activ

100 Although pressure changes in the pancreas can elevate cytosolic calcium (Ca2+) levels, it

101 o describe the indications for screening for pancreas cancer in high-risk individuals.

102 ete tumor regressions in a therapy-resistant pancreas cancer model, but only when combined with immun

103 Het to 84 tumor samples from 14 prostate and pancreas cancer patients, we identify subclonal CNAs and

104 counseling should be considered for familial pancreas cancer relatives who are eligible for surveilla

105 BEST PRACTICE ADVICE 6: Pancreas cancer screening in high-risk individuals shoul

106 12: Clinicians should consider discontinuing pancreas cancer screening in high-risk individuals when

107 BEST PRACTICE ADVICE 2: Pancreas cancer screening should be considered in patien

108 BEST PRACTICE ADVICE 1: Pancreas cancer screening should be considered in patien

109 E 13: The limitations and potential risks of pancreas cancer screening should be discussed with patie

110 reviewed in this work is based on reports of pancreas cancer screening studies in high-risk individua

111 n possible for high-risk patients undergoing pancreas cancer screening.

112 reening modalities in individuals undergoing pancreas cancer screening.

113 ding first-degree relatives of patients with pancreas cancer with at least 2 affected genetically rel

114 s with 1 or more first-degree relatives with pancreas cancer with Lynch syndrome, and mutations in BR

115 ndromes associated with an increased risk of pancreas cancer, including all patients with Peutz-Jeghe

116 uals when they are more likely to die of non-pancreas cancer-related causes due to comorbidity and/or

117 Our human pancreas cell atlas can be interrogated to understand pa

118 assay and with an IC(50) = 2.6 muM in human pancreas cells (HPAF-II).

119 eated the first comprehensive atlas of human pancreas cells including epithelial and nonepithelial co

120 Participation in a registry or referral to a pancreas Center of Excellence should be pursued when pos

121 in deficiency on the pancreas-to-skeleton-to-pancreas circuit has not been studied.

122 o American Society of Transplantation Kidney/Pancreas Community of Practice members and 202 US transp

123 000 genes differentially expressed in normal pancreas compared to primary INS.

124 of IL22 and the IL22 receptor (IL22R) in the pancreas compared with other tissues in mice; IL22 incre

125 not (111)In-IgG-TAT or (18)F-FDG, within the pancreas correlated positively with the age of KPC mice,

126 ow that the number of Pg translocated to the pancreas correlates with the number of bihormonal cells

127 with reduced levels of citrullination in the pancreas, decreased circulating autoantibody titers agai

128 in SLC26A9 expression in ductal cells of the pancreas delays the age at onset of diabetes, suggesting

129 re the requirement of O-GlcNAcylation during pancreas development and show that Ogt is essential for

130 enes, most significantly in genes related to pancreas development or function (GATA4, GATA6, PROX1, O

131 iation spanning a short time-window early in pancreas development, a phenotype we reproduced in mice.

132 Notch signaling is a major regulator of pancreas development, yet how it precisely controls panc

133 novel mechanistic link between nutrients and pancreas development.

134 endocrine and non-endocrine tissues in late pancreas development.

135 However, little is known about pig pancreas development.

136 e show the first evidence that Ogt regulates pancreas development.

137 and function suggest that porcine and human pancreas developmental biology may have useful homologie

138 ssing GATA6 expression and the efficiency of pancreas differentiation.

139 Salmonid alphavirus infection results in pancreas disease causing severe economic losses for Atla

140 ould help improve marker-based selection for pancreas disease resistance.

141 Among congenital conditions, annular pancreas, duplication cyst, superior mesenteric artery s

142 ational modification of proteins impacts the pancreas during development.

143 enzymatic and mechanical dissociation of the pancreas during islet isolation.

144 ession clusters of four highly expressed and pancreas-enriched genes (PRSS1, PNLIP, CLPS, and/or CELA

145 aries age 65 to 99 who underwent surgery for pancreas, esophageal, lung, rectal, and colon cancer fro

146 43,007 Medicare patients underwent either pancreas, esophageal, lung, rectal, or colon resection f

147 In the pancreas, excessive intracellular calcium causes mitocho

148 sive microdevice operating as an "artificial pancreas" for the release of insulin.

149 surrounding microenvironment is pivotal for pancreas formation and differentiation as well as adult

150 velopmental processes, including appropriate pancreas formation from the foregut endoderm.

151 ns at 2-year follow-up with normal liver and pancreas function.

152 t this benefit depends upon successful early pancreas function.

153 isolation of younger and fibrotic pediatric pancreases, gave increased islet yield with improved pat

154 t follow up, all 39 patients with functional pancreas graft had at least one comorbidity, such as hyp

155 %, 88.9%, and 76.0%; P = .3), death-censored pancreas graft survival (CACPR: 89.3%, 82.7%, 75.0%; non

156 sociated with lower probability of prolonged pancreas graft survival (hazard ratio: 0.52; confidence

157 Pancreas graft survival at 52 weeks, defined by insulin

158 tention to complications, some recipients of pancreas grafts have outstanding outcomes.

159 tional graft at last follow up and 9 (18.8%) pancreas grafts were lost due to patient death or graft

160 r inhibition of 12-LOX impairs both exocrine pancreas growth and unexpectedly, the generation of insu

161 77 liver, 286 lung, 213 heart, and 73 kidney-pancreas) had >=12 months of follow-up; 1520 patients (5

162 The uncinate process of the pancreas has an independent ductal drainage system.

163 islet, consisting of 1-2% mass of the whole pancreas, has long been believed to be regulated indepen

164 To date, the endocrine and exocrine pancreas have been studied separately by different field

165 The endocrine and exocrine pancreas have been studied separately by endocrinologist

166 impairs formation of endocrine cells of the pancreas head and tail.

167 The review focuses on kidney, liver, pancreas, heart, and lungs.

168 evidence that Men1 is essential for exocrine pancreas homeostasis in response to inflammation and onc

169 establishes Men1 as an important mediator of pancreas homeostasis in vivo.

170 ation and tumor suppression in the endocrine pancreas; however, intriguing recent data suggest MEN1 m

171 eterogeneity and cellular composition of the pancreas in neonates and adults in healthy and diseased

172 ssenger RNAs in pancreatic tumors and normal pancreas in The Cancer Genome Atlas.

173 underscore a potential role for the exocrine pancreas in the pathogenesis of type 1 diabetes.

174 d density of leukocytes) within the exocrine pancreas in this disease, but the mechanisms underlying

175 y, hazards for specific cancers (e.g. liver, pancreas) in type 2 patients cannot be explained by obes

176 vascular reconstruction of 65 kidneys and 5 pancreases, in 69 recipients.

177 ing analyses in hereditary and idiopathic CP pancreases indicate differences in innate and adaptive i

178 Acute Pancreatitis (AP) is sudden onset pancreas inflammation that causes systemic injury with a

179 hemogenetic stimulation of beta-cells and to pancreas infusion with serotonin, but were not sensitive

180 nhancement gradient (delta) across the tumor-pancreas interface was calculated.

181 ing a beneficial mitochondria-induced fat-to-pancreas interorgan signaling axis.

182 pro-inflammatory signaling in the endocrine pancreas involves activation of NF-kappaB, which is beli

183 Although the developing pancreas is exquisitely sensitive to nutrient supply in

184 Magnetic resonance imaging of the pancreas is increasingly used as an important diagnostic

185 ral damage from inflammation in the exocrine pancreas is not a likely cause of DM in these dogs.

186 here appear to be significant differences in pancreas islet cell lipid handling between species, and

187 hypothesized that transplanting simultaneous pancreas kidney (SPK) grafts from donors with a history

188 National Institutes of Health, simultaneous pancreas-kidney (SPK) recipients were randomized to a ca

189 In simultaneous pancreas-kidney (SPK) transplant recipients, the majorit

190 her kidney allocated for KAT or simultaneous pancreas-kidney transplant (SPK) (n = 7,378).

191 Successful simultaneous pancreas-kidney transplantation (SPK) improves quality-o

192 Tracer activity in the pancreas, kidneys, duodenum, and remainder of the body w

193 oal was to characterize EW gain after kidney-pancreas (KP) transplantation.

194 Pancreas, large and small intestines demonstrated lower

195 d be considered when there are no concerning pancreas lesions, with shortened intervals and/or the pe

196 0-day postoperative events following complex pancreas, liver, and rectal surgeries, and liver transpl

197 H&E staining revealed overt lesions in the pancreas, liver, kidney, esophagus, duodenum, and ileum

198 or types (including colon, breast, prostate, pancreas, lung adenocarcinoma, and squamous cell carcino

199 phagus, stomach, colon, rectum, anus, liver, pancreas, lung, breast, cervix uteri, and prostate) comp

200 s Cre under tissue-specific promoters of the pancreas, mammary gland and other secretory tissues, as

201 Expression of PRSS1R122H protein in the pancreas markedly increased stress signaling pathways an

202 Kazal type 1 (SPINK1) by mesotrypsin in the pancreas may contribute to the pathogenesis of pancreati

203 insulin delivery (also called an artificial pancreas) may improve glycemic outcomes in children with

204 The concentration of iodine in the pancreas measured with dual-energy CT differs significan

205 cancer types, including breast, lung, ovary, pancreas, melanoma, bone, and brain tumors.

206 olism and cell cycle regulation in endocrine pancreas (miR-15a and miR-17).

207 oscillating Notch activity in the developing pancreas, modulated by Jag1, is required to coordinate M

208 Similarities of pancreas morphology and function suggest that porcine an

209 lood flow between the endocrine and exocrine pancreas, not necessarily a unidirectional blood flow as

210 Moreover, immune cells infiltrating the pancreas of humans with T1D exhibited increased expressi

211 an important ferroptosis suppressor, in the pancreas of mice with cerulean- or L-arginine-induced pa

212 clear fluorescent signal was detected in the pancreas of mini pigs.

213 the fluorescent signal of the tracer in the pancreas of mini pigs.

214 observed among GC Tfh cells infiltrating the pancreas of NOD mice, which was enhanced by loss of SAP

215 GLP-1 and CCK are produced in the endocrine pancreas of obese mice.

216 assessment of the pathology of the endocrine pancreas of patients with LADA and for comparison in a f

217 as those affecting the GI tract, liver, and pancreas, on which this review is focused.

218 Patients who had colorectal, liver, and pancreas operations abstracted in 2011-2017 ACS NSQIP Pa

219 evelopment of invasive cancer in the remnant pancreas or metastatic disease.

220 Independent pancreas outlines by two board-certified radiologists (n

221 D accumulation in the intact human and mouse pancreas over a range of ages and states of diabetes.

222 gs suggest that Pg/gingipain translocates to pancreas, particularly beta-cells in both humans and mic

223 clinical investigation of diabetes and other pancreas pathologies.

224 (MECSE) gradient-echo sequence for liver and pancreas PDFF quantification.

225 luding donor selection, pancreas processing, pancreas perfusion and digestion, islet counting and cul

226 ins many of the matrix components present in pancreas, prior to islet transplantation.

227 t critical steps, including donor selection, pancreas processing, pancreas perfusion and digestion, i

228 ve care unit length, amylase concentration), pancreas procurement, isolation procedures (brand and co

229 lying pathology in human as well as rat LADA pancreases provided identical results, allowing the conc

230 deficit should be discussed with prospective pancreas recipients given the potential impact on posttr

231 As the number of pancreas recipients with prolonged graft survival may be

232 measurement of the degree of overlap between pancreas regions of interest between the two readers, wa

233 and pSTAT3 in the PanIN lesions of KC mouse pancreas reinforces the crucial involvement of MUC5AC in

234 icient immunosuppression to reliably prevent pancreas rejection in SPK transplants undergoing CNI wit

235 til CNI was withdrawn, with four of the five pancreas rejections occurring during or after CNI withdr

236 to comorbidity and/or are not candidates for pancreas resection.

237 ain fluids of 128 consecutive patients after pancreas resection.

238 ction of insulin-producing beta-cells of the pancreas, resulting in dependence on exogenously adminis

239 borating earlier results obtained from human pancreas sections.

240 Human and rat LADA pancreases showed differences in areas of the pancreas w

241 ssues that regulate metabolism including the pancreas, skeletal muscle, and adipose tissue, its funct

242 ing tissue-specific RNA-sequencing data from pancreas, small intestine, ovary, kidney, and heart with

243 rson Cancer Center group (MDA) and the Japan Pancreas Society (JPS) have introduced other grading sys

244 EKPC mice with pancreas-specific deletion of HIF1A developed more advan

245 epithelial cells (EKPC), and EKPC mice with pancreas-specific depletion of HIF1A.

246 We studied mice with pancreas-specific disruption of Prkd1 (PRKD1(KO) mice),

247 Here, we show that pancreas-specific Hnf1a null mutant transcriptomes pheno

248 heterotopic skin tumours in mice to restrict pancreas-specific tumour growth.

249 cal analyses of 26 PDACs and 5 nonneoplastic pancreas specimens.

250 n 3 months (SPK,P-) and 94% had a functional pancreas (SPK,P+).

251 s to a pathological process in the endocrine pancreas, suggesting pancreatitis might be a potential p

252 isted for remote IPMNs limited to the dorsal pancreas, suggesting UDD may be associated with an aggre

253 integrated blood flow throughout the entire pancreas suggests direct interactions between islet endo

254 ords: Abdomen/GI, Genetic Defects, Oncology, Pancreas Supplemental material is available for this art

255 l patients receive their care at high-volume pancreas surgery centers.

256 uptake of (111)In-anti-gammaH2AX-TAT in the pancreas survive for a significantly shorter time than m

257 Pancreas SUV ratio minus 1 (SUVR-1) (20-30 min; spleen a

258 iabetes did not significantly correlate with pancreas SUVR-1 (20-30 min) (R (2) = 0.36, P = 0.16).

259 e at diagnosis correlated significantly with pancreas SUVR-1 (20-30 min) (R (2) = 0.67, P = 0.025).

260 Centrally, vagal neurons projecting to the pancreas terminate in the commissural nucleus of the sol

261 ry numbers, but not of perivascular cells in pancreas, testis and thyroid gland, with age in mice and

262 betes includes abnormalities in the exocrine pancreas that may induce endocrine cellular stress as a

263 vation caused a metaplastic phenotype in the pancreas that was missing in mice with acinar-specific p

264 For example, for pancreas the lowest-spending hospitals on average discha

265 I enables the diagnosis and grading of fatty pancreas through simple chemical shift techniques.

266 8 children-digest islet equivalents per gram pancreas tissue (IEQ/g) and digest IEQ per kilogram body

267 ation: (a) poor yield of islets from donated pancreas tissue and (b) the need for life-long immunosup

268 s were obtained from multiple centres: Barts Pancreas Tissue Bank, University College London, Univers

269 We illustrate our approach on heterogeneous pancreas tissues obtained from healthy mice.

270 reatic cancer specimens compared with normal pancreas tissues.

271 er from DM links the disease in the exocrine pancreas to a pathological process in the endocrine panc

272 ranges from quasi-experimental work in human pancreas to multiple meta-analyses of Randomized Control

273 steoblast-specific insulin deficiency on the pancreas-to-skeleton-to-pancreas circuit has not been st

274 K3(bright+) dataset with a single-cell whole-pancreas transcriptome.

275 Reports of GVHD in kidney and pancreas transplant recipients almost uniformly describe

276 transplantation, rarely occurs in kidney and pancreas transplant recipients.

277 All UK pancreas transplant units were surveyed between 2017 and

278 ch were diagnosed at 5.5 and 42 months after pancreas transplant.

279 first case report of simultaneous liver and pancreas transplantation as treatment of WRS in a small

280 ntial for survival of patients with WRS, and pancreas transplantation cures their type I diabetes mel

281 a nonacute, combined, simultaneous liver and pancreas transplantation from a pediatric donor without

282 There have been 6 cases of SCI during pancreas transplantation since 2002.

283 may be a metabolic consequence of successful pancreas transplantation that results in EW gain in a pr

284 The risk of SCI in pancreas transplantation was estimated using the number

285 As) are an invaluable resource in kidney and pancreas transplantation when vascular reconstruction is

286 o combat type 1 diabetes (T1D) include donor pancreas transplantation, exogenous insulin administrati

287 here is approximately a 1:440 risk of SCI in pancreas transplantation.

288 se data demonstrate that MRI measurements of pancreas volume between two readers are repeatable and r

289 tability and inter-reader reproducibility of pancreas volume measurements by MRI.

290 Reduced pancreas volume, as measured by non-contrast magnetic re

291 ts, as stomach volume did not correlate with pancreas volume.

292 the Cox regression analysis, bladder drained pancreas was associated with lower probability of prolon

293 biopsy-proven acute rejection (BPAR) of the pancreas was low in both groups until CNI was withdrawn,

294 o mimic the physiological oxygenation of the pancreas, we demonstrate high viability and preserved en

295 To directly assess the role of NKG2D in the pancreas, we generated NOD mice that express an NKG2D li

296 e esophagus, stomach, colorectum, liver, and pancreas were extracted from the GLOBOCAN database for t

297 Islets in human and rat pancreases were analyzed by immunohistochemistry for imm

298 inuously integrated to those in the exocrine pancreas, which made the islet circulation rather open,

299 eadily migrate into lymphoid tissues and the pancreas while inhibiting autoantibodies.

300 ancreases showed differences in areas of the pancreas with respect to immune cell infiltration and a