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1 ppocampal formation in the brain of the tree pangolin.
2  specialized auditory processing in the tree pangolin.
3 ance of the brain of the rarely studied tree pangolin.
4  that nuclear retention is dependent on dTCF/Pangolin.
5 he nucleus, where it cooperates with Arm and Pangolin.
6 ing Chinese rufous horseshoe bat and Malayan pangolin.
7 onse to a viral skin infection in a deceased pangolin.
8 not in closely related viruses from bats and pangolins.
9 avior of less commonly studied species, like pangolins.
10 ns related to the myrmecophagous diet of the pangolins.
11 arding the phylogeny and life history of the pangolins.
12 mblance to that of baleen whales [7] than to pangolins.
13 anis javanica) and Chinese (M. pentadactyla) pangolins.
14 to understand the lipid metabolism system in pangolins.
15 y be highly relevant for the conservation of pangolins.
16 inoceros horn, and novel farming methods for pangolins.
17 ated from bats; 4) nine SL-CoV isolated from pangolins; 5) three SL-CoVs isolated from civet cats; an
18 us resemblances that have made anteaters and pangolins a textbook example of convergent evolution.
19                                              Pangolin, a component of the Wingless pathway, is requir
20                             Here, we present Pangolin, a deep learning model to predict splice site s
21 ely abrogated the usage of horseshoe bat and pangolin ACE2 but enhanced the usage of mouse ACE2 by th
22 ed to SARS-CoV-2, bind strongly to human and pangolin ACE2 receptors.
23                               Interestingly, pangolin ACE2 showed the next highest binding affinity d
24                             In addition, the pangolin and bat coronaviruses, Pangolin-CoV-2020 and Ba
25  the relative levels of activating Armadillo/Pangolin and repressing Groucho/Pangolin complexes prese
26        The sequence lineages were typed with pangolin and the phylogenetic analysis was conducted wit
27 iruses that have been identified in bats and pangolins and that have the potential to cause human inf
28 ncluding human, rhesus macaques, mouse, pig, pangolin, and bat, suggesting a conserved infection path
29 e data are augmented with alignments of bat, pangolin, and other animal and human coronavirus genomes
30                              Instead, 97% of pangolins are captured opportunistically or during gener
31                                              Pangolins are considered the most trafficked mammals in
32                                      African pangolins are hunted for their meat and for use in local
33 beta-CoVs countermeasures.IMPORTANCEBats and pangolins are natural reservoirs of betacoronaviruses (b
34                                              Pangolins are of conservation concern as one of the most
35                                              Pangolins are scale-covered mammals, containing eight en
36  repeated zoonotic transfers between bat and pangolin as a reservoir for future zoonotic transfers to
37 detected in bats of the same colony and in a pangolin at a wildlife checkpoint in Southern Thailand.
38  on the reproductive behavior of the Chinese pangolin based on the monitoring of a female (LF28) usin
39 s, artiodactyls, perissodactyls, carnivores, pangolins, bats and core insectivores).
40 y, threat level, and use type: rhinoceroses, pangolins, bears, sturgeon, horseshoe crabs, and caterpi
41 ucted from 11 gene trees for human, bat, and pangolin beta coronaviruses from samples taken early in
42 e of recent gene flow events between bat and pangolin beta coronaviruses predating the zoonotic trans
43                               To investigate pangolin biology and evolution, we developed genome asse
44  features visible on the surface of the tree pangolin brain, and its overall appearance can be descri
45 ntinue our analysis of the brain of the tree pangolin by providing a comprehensive description of the
46 s of transmembrane receptors and the TCF/LEF/Pangolin class of transcription factors.
47 ected population growth in the white-bellied pangolin coinciding with a dry period during the Pleisto
48 ng Armadillo/Pangolin and repressing Groucho/Pangolin complexes present and to the responsiveness of
49 al chemistry, and fiber pathways of the tree pangolin conform to that typically observed across more
50 3 (Bat-CoV RaTG13) and a recently identified pangolin coronavirus (Pangolin-CoV-2020).
51                         Some human, bat, and pangolin coronavirus lineages found in China are phyloge
52 pike protein between a bat coronavirus and a pangolin coronavirus that endows it humans infectivity.
53 DB formation is conserved in related bat and pangolin coronaviruses but was lost during the evolution
54  pre-miRNA sequences with those from bat and pangolin coronaviruses suggests that single nucleotide m
55                                 However, the pangolin CoV is potentially infectious to humans.
56    We also report the cryo-EM structure of a Pangolin-CoV spike protein and show it adopts a fully-cl
57 ddition, the pangolin and bat coronaviruses, Pangolin-CoV-2020 and Bat-CoV RaTG13, were also found ab
58  a recently identified pangolin coronavirus (Pangolin-CoV-2020).
59 n SARS-CoV-2 that is also present in Guangxi pangolin-CoVs but not other closely related pangolin-CoV
60  pangolin-CoVs but not other closely related pangolin-CoVs or bat-CoVs.
61           We show that spikes from Guangdong Pangolin-CoVs, closely related to SARS-CoV-2, bind stron
62 t tooth innervation, while equally toothless pangolins do not.
63 ould receive specific monitoring to mitigate pangolins' domestic trafficking.
64               The visual portion of the tree pangolin dorsal thalamus appears to be organized in a ma
65 lp by Wg involves binding of the Wg effector Pangolin (Drosophila Lef-1/TCF) to multiple binding site
66 by directly targeting the 3'-UTRs of arm and pangolin (Drosophila TCF) in vivo.
67 iously unnamed zinc finger gene (cucoid), or pangolin (dTcf), respectively.
68 he diencephalon and hypothalamus of the tree pangolin follow the organization typically observed acro
69  Here, we investigate the behaviour of these pangolins, for the first time, using a battery of cognit
70 e first controlled experiment to investigate pangolin foraging behaviour and cognition, which may hav
71 d trace its domestic trade, we genotyped 562 pangolins from local to large bushmeat markets in wester
72 pt at the anterior egg pole, suggesting that pangolin functioned as ancestral axis determinant in fli
73 , WIV-1, SHC014, SARS-CoV-2 D614G, BA.1, and Pangolin-GD) and vesicular stomatitis virus-pseudotyped
74 iants, SARS-CoV, and pre-emergent SHC014 and Pangolin/GD coronavirus strains.
75 rotein derived from either the bat RaTG13 or pangolin GX, two closely related animal coronaviruses, u
76 ve implications for the future protection of pangolin habitat based on the location of prey species.
77 naling components, beta-cat/armadillo or TCF/pangolin, had relatively milder effects on cardiac funct
78  overall call rate genome-wide, SpliceAI and Pangolin have superior sensitivity.
79                    Coronaviruses of bats and pangolins have been implicated in the origin and evoluti
80  pangolin trafficking, we show that targeted pangolin hunts are uncommon in the country's largest pan
81                                 In addition, Pangolin identifies loss-of-function mutations with high
82                                              Pangolin improves prediction of the impact of genetic va
83         Spliformer outperformed SpliceAI and Pangolin in both speed and accuracy in tested splicing e
84 to set up conservation strategies for Indian pangolin in Pakistan.
85  current and future habitat ranges of Indian pangolin in the face of a changing climate.
86                                  Maintaining pangolins in captivity is a significant challenge, in pa
87 arities and differences observed in the tree pangolin indicate that the hippocampal formation is an a
88                            The white-bellied pangolin is subject to intense trafficking, feeding both
89 ajority (88%) of the samples belonged to the pangolin lineage B.1.1.25, whereas the remaining 11% wer
90                             We identified 31 Pangolin lineages of SARS-CoV-2, the majority belonging
91 tion between Sundaland and Indochinese Sunda pangolin lineages.
92 ecasted future distribution ranges of Indian pangolin (Manis crassicaudata) under climate change scen
93 e analysed mitogenome sequences of the Sunda pangolin (Manis javanica) from across their Southeast As
94                                    The Sunda pangolin (Manis javanica) in particular is a critically
95                      Observations of Chinese pangolin (Manis pentadactyla) in the wild are extremely
96                       We obtained 560 Indian pangolin occurrences overall, 175 during the study, and
97                              We note that no pangolins (or bats) were traded, supporting reformed opi
98        Phylogenetic analyses have placed the pangolins, order Pholidota, as a sister group to the ord
99                                              Pangolin outperforms state-of-the-art methods for predic
100 in composed of the regulatory domain of dTCF/Pangolin (Pan) and the DNA binding domain of Ci.
101                The transcription factor dTcf/Pangolin (Pan) is the final effector of the Wg pathway i
102                   RNA interference of wg and pangolin (pan) produce defects in the germband and eyes,
103 cluding wntless (wls), porcupine (porc), and pangolin (pan).
104  number of binding sites for the Wg-effector Pangolin (Pan/Lef-1), which are required for full levels
105                Here we recovered a wild-type pangolin (Pg) CoV GD strain including derivatives encodi
106 ecies of African pangolin, the white-bellied pangolin (Phataginus tricuspis) and the giant pangolin (
107                            The white-bellied pangolin (Phataginus tricuspis) is the world's most traf
108 ificantly contribute to our understanding of pangolin population biology and local trade dynamics.
109 o the evolutionary relationships among Sunda pangolin populations in Southeast Asia, building on othe
110       While the stable habitat of the Indian pangolin ranged between 64.60 and 83.85% under all SSPs
111 scales, but substantial sampling gaps across pangolins' ranges hinder these efforts.
112 our data from a previously unstudied part of pangolins' ranges will help us to better understand inte
113  gene families are significantly expanded in pangolins, reflecting their well-developed olfaction sys
114                                      African pangolins, regarded as the world's most trafficked wild
115                          We suggest that the pangolin's innate gene pseudogenisation is indeed likely
116                                              Pangolin's population genetic structure can be used to t
117  the bat sarbecovirus WIV1, BANAL-236, and a pangolin sarbecovirus.
118                        We found that bat and pangolin sarbecoviruses showed significantly less neutra
119  coronaviruses (CoVs) identified in bats and pangolins, SARS-CoV-2 harbors a polybasic furin cleavage
120                                 SpliceAI and Pangolin show the best overall performance among predict
121 sponses were not upregulated in the infected pangolin skin.
122 angolin (Phataginus tricuspis) and the giant pangolin (Smutsia gigantea) in the underexplored Republi
123 tion of the Critically Endangered East Asian Pangolin species is hampered by the vulnerability of cap
124 y, is pseudogenized in all African and Asian pangolin species that we examined, perhaps impacting res
125  and connectivity among populations of Asian pangolin species, hampering effective conservation manag
126  to coronaviruses infecting bats and Malayan pangolins, species suspected to be an intermediate host
127  M. javanica and other mammals revealed many pangolin-specific genes significantly over-represented i
128  hunts are uncommon in the country's largest pangolin stronghold.
129 the remaining species, ACE2s from rabbit and pangolin strongly bound to the S1 subunit of SARS-CoV-2
130 o and blocked by a dominant negative form of pangolin/TCF.
131  unusual locus coeruleus complex of the tree pangolin, the superior olivary nuclear complex of the au
132 e and dynamics in the two species of African pangolin, the white-bellied pangolin (Phataginus tricusp
133 t current and future distributions of Indian pangolin, then computed the amount of habitat lost, gain
134 t), poultry (duck and pigeon), and wildlife (pangolin, tiger, and deer), and investigated the co-expr
135            Studies have previously shown the pangolin to have a unique pseudogenisation of many immun
136 es, applied the in silico tools SpliceAI and Pangolin to predict variants of functional consequence,
137 port the genetic traceability of the illegal pangolin trade.
138 mmend a multi-locus approach for tracing the pangolin trade.
139 dors in Nigeria, the world's biggest hub for pangolin trafficking, we show that targeted pangolin hun
140 rane flies (Nephrotoma) also enrich maternal pangolin transcript at the anterior egg pole, suggesting
141                                              Pangolins, unique mammals with scales over most of their
142    We collected occurrence records of Indian pangolin using burrow counts, remote camera records and
143  benchmarked Spliformer against SpliceAI and Pangolin using testing datasets and paired whole-genome
144 ction against injuries or stress and reduced pangolin vulnerability to infection.
145 me period highly suitable habitat for Indian pangolin was (7270 km(2), 2.2%), followed by moderately
146 d loss in the suitable habitat of the Indian pangolin was greatest (26.97%) under SSP 585 followed by
147       The gain in suitable habitat of Indian pangolin was less than that of losses on average which r
148  analysis was done using ARTIC pipelines and Pangolin was used to assign lineages.
149 dscape genetics, we found all but one of the pangolins we sampled at bush meat markets originated loc
150 izures representing nearly 1 million African pangolins, we identified Nigeria as one important hub fo
151 rts of the hippocampal formation of the tree pangolin were consistent with that observed in other mam
152 ulation remains mysterious, although bat and pangolin were proposed to be the natural reservoirs.
153  of two containers was baited with food, the pangolins were able to find the food with olfactory info
154         Subsequently, betacoronaviruses from pangolins were identified as close relatives to SARS-CoV
155 ere traded, supporting reformed opinion that pangolins were not likely the spillover host at the sour
156 le, horses, goats, sheep, cats, rabbits, and pangolins, were able to support cell entry of SARS-CoV-2
157 t mitochondrial lineage of the white-bellied pangolin, which was most likely shaped by river barriers
158 RS-CoV and sarbecovirus strains from bat and pangolin zoonotic origin.

 
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