ライフサイエンスコーパス: paraben

1 , lotion (BP-3 and parabens), and cosmetics (parabens).

2 08 (2005-2008 for analyses of phthalates and parabens).

3 elatively low for BPA to moderate for propyl paraben.

4 ng and added a preservative containing ethyl paraben.

5 us 24 hr had higher concentrations of propyl paraben.

6 enol A to a high of > 180,000 ppm for methyl paraben.

7 t weight) for all analytes except for methyl paraben.

8 ctrophoresis (CE) for the extraction of four parabens.

9 , antioxidants, UV filters, musks, PBDEs and parabens.

10 levels of several phthalate metabolites and parabens.

11 men's exposures to environmental phenols and parabens.

12 between the active site of FsC and different parabens.

13 cal significance for some LMW phthalates and parabens.

14 inated diphenyl ethers (PBDEs), 3 phenols, 4 parabens, 10 phthalates, 4 organophosphate pesticides, 5

15 e sum of parabens (methyl, ethyl, and propyl parabens), 2,5-dichlorophenol, and triclosan.

16 te de l'Enfant) cohort for whom 9 phenols (4 parabens, 2 dichlorophenols, triclosan, benzophenone-3,

17 ary concentrations of five phenols and three parabens: 2,4-dichlorophenol (24-DCP), 2,5-dichloropheno

18 mong the four countries studied, the EDIs of parabens (5.4 ng/kg-bw/day) and BADGEs (6.5 ng/kg-bw/day

19 low those of phthalates (6431 pg/g f.w.) and parabens (6234 pg/g f.w.).

20 The removal efficiencies for parabens (89.6-99.9%) were higher than those for their m

21 An extraction efficiency of 86-101% for all parabens achieved using the optimum-sized cartridge and

22 The effects of HER ligands on paraben activation of c-Myc expression and cell prolifer

23 was observed in patch-clamp experiments with parabens added from either the cytoplasmic or periplasmi

24 Parabens (alkyl esters of p-hydroxybenzoic acid) are wid

25 Limited evidence on parabens also failed to demonstrate a clear link with GD

26 Concentrations of parabens also were determined in sewage sludge collected

27 th lower concentrations of propyl and methyl parabens among men.

28 tions were found among the concentrations of paraben analogues in sediment and sludge, which suggeste

29 In this study, six paraben analogues, methyl- (MeP), ethyl- (EtP), propyl-

30 res to mono-hydroxyisononyl phthalate, ethyl paraben and 4-ethylbenzoic acid were associated with met

31 with altered respiratory health, with ethyl-paraben and bisphenol A exhibiting some consistency acro

32 ined the cross-sectional association between parabens and asthma morbidity among 450 children with as

33 Concentrations of four phthalates, seven parabens and BPA were determined in forty-two milk produ

34 ne incorporation differed between brominated parabens and brominated salicylates, suggesting that the

35 In this study, six parabens and four common metabolites of parabens were me

36 Parabens and human epidermal growth factor receptor liga

37 Human exposure to parabens and other antimicrobial chemicals is continual

38 The positive association between the sum of parabens and placental weight was consistent with result

39 Parabens and salicylates were examined as disinfection b

40 ds into C-Cl bonds was confirmed for several parabens and salicylates.

41 entrations of 11 target chemicals, viz., six parabens and their common hydrolysis product, 4-hydroxyb

42 le is known about the occurrence and fate of parabens and their metabolites in wastewater treatment p

43 The environmental emission of parabens and their metabolites through WWTP discharges w

44 The respective mass loadings of parabens and their metabolites were 46.3 and 6210 mg/d/1

45 ls, including phthalates and phenols such as parabens and triclosan, is ubiquitous within the U.S. ge

46 p-Hydroxybenzoic acid esters (parabens) and bisphenol A diglycidyl ether (BADGE) are w

47 ap (TCS), sunscreen (BP-3), lotion (BP-3 and parabens), and cosmetics (parabens).

48 emical combination (2-phenoxyethanol, methyl paraben, and ethyl paraben) appears in 1,059 products.

49 ed total and free BPA, butyl paraben, propyl paraben, and methyl paraben in 100% of samples, total be

50 Reducing phthalate, paraben, and phenol exposure from personal care products

51 Triclosan, methyl paraben, and propyl paraben concentrations were quantifi

52 s of biomarkers of diethyl phthalate, methyl paraben, and triclosan in rats.

53 FAS), 10 phthalate metabolites, 3 phenols, 4 parabens, and 4 organophosphate pesticide metabolites me

54 e is documented widespread human exposure to parabens, and some experimental data suggest that they a

55 mples contained measurable concentrations of parabens, and the total concentrations (Sigmaparabens; s

56 presence of endocrine disrupting chemicals, parabens, and their metabolites is of concern.

57 enols and triclosan), phthalate metabolites, parabens, and triclocarban measured in prenatal urine sa

58 ophenone-3; propyl, methyl, butyl, and ethyl parabens; and specific IgE levels were available for 860

59 (2-phenoxyethanol, methyl paraben, and ethyl paraben) appears in 1,059 products.

60 Despite evidence of estrogenicity, parabens are among the most widely used xenoestrogens in

61 Parabens are broad-spectrum antimicrobial preservatives

62 Parabens are common preservatives and environmental horm

63 Parabens are compounds used as chemical preservatives in

64 Parabens are emerging environmental contaminants with kn

65 Parabens are esters of p-hydroxybenzoic acid and are wid

66 The parabens are extracted from the samples using SPME, and

67 Parabens are preservatives commonly used in personal car

68 Parabens are preservatives that are widely used in cosme

69 Parabens are suspected endocrine disruptors and ubiquito

70 Parabens are synthetic preservatives present in many con

71 p-Hydroxybenzoic acid esters (parabens) are amphipathic compounds widely used as food

72 e products, such as phenols, phthalates, and parabens, are potentially modifiable and plausibly linke

73 ysis of the samples by SPME-IMS using benzyl paraben as an internal standard yields good comparison t

74 ), bisphenol A (BPA), triclosan (TCS), butyl paraben (B-PB), methyl paraben (M-PB), and propyl parabe

75 henol, butyl paraben, methyl paraben, propyl paraben, benzophenone-3, bisphenol A, and triclosan in u

76 phthalate metabolites and nine phenols (four parabens, benzophenone-3, BPA, two dichlorophenols, tric

77 The fecal excretion rates of parabens, benzophenones, bisphenols, naphthalene, 2,4-di

78 sion to examine associations between urinary paraben biomarker concentrations (butyl paraben, ethyl p

79 We sought to measure phenol and paraben biomarker concentrations for the Norwegian Mothe

80 Ethyl-paraben, bisphenol A, 2,5-dichlorophenol, and DIDP tende

81 The compounds that contain a phenolic ring (parabens, bisphenol A, and triclosan) were completely tr

82 Other exposures (total parabens, bisphenol A, triclosan, benzophenone-3, total

83 hat cytoplasmically presented ethyl or butyl parabens both hasten the process of desensitization of M

84 tions of methyl (MP), propyl (PP), and butyl paraben (BP) among couples from a fertility center.

85 DEP), di-n-butyl phthalate (DnBP), and butyl paraben (BP) and diluted to make creams with concentrati

86 zoate (SB), potassium sorbate (PS) and Butyl paraben (BP) have been widely used in food and pharmacy

87 confirmed-including two alkylphenols, ethyl paraben, BPF, PFOSAA, benzophenone-3, benzyl p-hydroxybe

88 MeP), ethyl- (EtP), propyl- (PrP), and butyl parabens (BuP) were on the order of 1000 mug per gram of

89 sphenol F, bisphenol S, and triclosan), four parabens [butyl paraben, ethyl paraben (ETPB), methyl pa

90 organic emerging contaminants (viz., methyl paraben, butyl paraben, diclofenac, and triclosan) from

91 ruits, and vegetables, and analyzed for five parabens by high-performance liquid chromatography-tande

92 d differential effects of exposure to select parabens by sex on asthma morbidity.

93 The EDI values of total parabens (calculated from the mean concentrations measur

94 estigated the hypothesis that the potency of parabens can be increased with HER ligands, such as here

95 24 h had significantly higher geometric mean paraben concentrations (80-110%) in their urine than wom

96 n models to estimate associations of urinary paraben concentrations (in tertiles) with ovarian reserv

97 Paraben concentrations [methylparaben (MP), propylparabe

98 There were no significant differences in paraben concentrations among the eight food categories,

99 between prenatal and early-life triclosan or paraben concentrations and childhood asthma, recurrent w

100 ere fit to examine demographic predictors of paraben concentrations and to calculate intraclass corre

101 Methyl and propyl paraben concentrations decreased by 43.9% (95% CI: -61.3

102 ng to PRISMA guidelines, this study analyzes paraben concentrations in foods globally, with no tempor

103 tal sensitization associated with increasing paraben concentrations in male compared with female subj

104 xpectedly, concentrations of ethyl and butyl paraben concentrations increased, although concentration

105 Among 129 pregnant women, urinary paraben concentrations were 25-45% lower during pregnanc

106 Urinary paraben concentrations were more variable in women compa

107 Triclosan, methyl paraben, and propyl paraben concentrations were quantified in maternal plasm

108 maternal plasma or child urine triclosan or paraben concentrations with asthma or recurrent wheeze o

109 We examined the association of urinary paraben concentrations with markers of ovarian reserve i

110 luated predictors and variability of urinary paraben concentrations.

111 d predicted a 254-1,333% increase in MEP and parabens concentrations.

112 allowed us to identify likely BPA and butyl paraben contamination of archived MoBa urine specimens.

113 investigate any possible external phenol or paraben contamination of specimens.

114 e findings and elucidate mechanisms by which parabens could affect respiratory health and elicit dimo

115 itial catalytic activity after six rounds of paraben degradation reaction.

116 ng contaminants (viz., methyl paraben, butyl paraben, diclofenac, and triclosan) from exposed mussels

117 However, previous cell-based studies with parabens do not take into account the signaling cross-ta

118 lar associations were observed between ethyl paraben (EP) and couple fecundity for both partner and c

119 enol S, and triclosan), four parabens [butyl paraben, ethyl paraben (ETPB), methyl paraben (MEPB), an

120 nary paraben biomarker concentrations (butyl paraben, ethyl paraben, methyl paraben [MP], and propyl

121 closan), four parabens [butyl paraben, ethyl paraben (ETPB), methyl paraben (MEPB), and propyl parabe

122 The regression equations of these parabens exhibited good linearity (r(2)=0.998, 0.1-10mug

123 an inverse association between triclosan and paraben exposure and allergic sensitization was observed

124 etween prenatal and early-life triclosan and paraben exposure and childhood allergic disease in a pro

125 Here, we investigated whether prenatal paraben exposure can influence the risk for atopic derma

126 odestly increased internal LMW phthalate and paraben exposure in 4-9 year old children.

127 The differential effects of triclosan or paraben exposure on allergic sensitization by sex observ

128 er worldwide controls are required to reduce paraben exposure through food.

129 e reproductive health effects in relation to paraben exposure.

130 netic predisposition are more susceptible to paraben exposure.

131 reclude possible adverse effects of paternal paraben exposures on such outcomes, given the modest sam

132 assisted cloud point extraction (SA-CPE) for paraben extraction.

133 trated successful enzyme-mediated removal of parabens for the first time.

134 iciencies, and environmental emission of six parabens, four of their metabolites (4-hydroxy benzoate,

135 Back-extraction of parabens from chloroform into a 50mM sodium hydroxide so

136 nique was better suited to the extraction of parabens from complex matrices.

137 In contrast, dermal intake of parabens from PCPs by infants and toddlers was higher th

138 Widespread exposure of humans to parabens has raised significant public health concerns.

139 PrP), butyl- (BuP), benzyl-(BzP), and heptyl parabens (HepP), were determined in surface sediment and

140 PCPs) are exposure sources to phthalates and parabens; however, their contribution to men's exposure

141 A, butyl paraben, propyl paraben, and methyl paraben in 100% of samples, total benzophenone-3 in 95%

142 were modified successfully to determine four parabens in 19 commercial products.

143 nd within-person variability for phenols and parabens in a MoBa sample (n = 45), including a subgroup

144 chlorophenol, 2,5- dichlorophenol, and three parabens in at least 60% of the pools suggesting childre

145 ot consistently associated with TCS or total parabens in children or adolescents of either sex.

146 table applicability for the determination of parabens in complex matrices.

147 c method that simultaneously determines four parabens in complex samples such as sweeteners without a

148 concentrations of phthalate metabolites and parabens in Danish children.

149 Concentrations of sum of six parabens in dust were on the order of several hundred to

150 Information on the occurrence of parabens in foodstuffs and dietary exposure of humans to

151 the first study to report the occurrence of parabens in foodstuffs.

152 an effective medium for determination of the parabens in human breast milk samples using micro solid

153 le and rapid method for the determination of parabens in human milk and food with relative recoveries

154 ducts (BADGEs) in indoor dust samples and of parabens in indoor dust from Asian countries.

155 and quartiles of urinary BPA, BP-3, TCS, and parabens in male and female children (ages 6-11 years) a

156 s, little is known about the accumulation of parabens in marine organisms.

157 concentrations of phthalate metabolites and parabens in men.

158 spite the widespread usage of phthalates and parabens in personal care products (PCPs), little is kno

159 Vertical profiles of parabens in sediment cores from the U.S. showed a gradua

160 Thus, the determination of parabens in such products is of particular importance.

161 mistry alternative for advanced treatment of parabens in sustainable water reclamation.

162 mination of methyl, ethyl, propyl, and butyl parabens in sweeteners.

163 ern, little is known about the occurrence of parabens in the environment.

164 The detection of parabens in the placenta or amniotic fluid raised concer

165 es but may not be the primary target for the parabens in their antimicrobial activity.

166 No studies have assessed the variability of parabens in women, including during pregnancy.

167 of parabens (methyl, ethyl, propyl and butyl paraben) in different samples (food, cosmetics and water

168 chemicals (i.e., benzophenone-3, triclosan, parabens) in human urine, milk, and serum to identify po

169 phenol A, benzophenone-3, and triclosan) and parabens is widespread in the population.

170 posure to phenols, including bisphenol A and parabens, is widespread.

171 nt of the sum of six parent parabens (Sigma6 Parabens) leached from teethers ranged from 2.0 to 1990

172 bisphenol A, benzophenone-3, triclosan, and paraben levels in male and female children and adolescen

173 Phthalate metabolite and paraben levels were generally higher in children with fr

174 In this group are common parabens, lower molecular weight phthalates, o-phenylphe

175 in comparison with sorbates (5% of ADI) and parabens (<1% of ADI), when mean consumption is consider

176 riclosan (TCS), butyl paraben (B-PB), methyl paraben (M-PB), and propyl paraben (P-PB).

177 Parabens may be added to cosmetic and personal care prod

178 Exposures to environmental phenols and parabens may be harmful, especially in utero.

179 All parabens measured in maternal urine had moderate to high

180 Methyl paraben (MeP) was the predominant compound found in the

181 Methyl paraben (MeP), propyl paraben (PrP), BADGE.2H(2)O, and B

182 [butyl paraben, ethyl paraben (ETPB), methyl paraben (MEPB), and propyl paraben (PRPB)], and tricloca

183 droxybenzoic acid (4-HB) was the predominant paraben metabolite found in all tissue samples.

184 ens (Sigmaparabens = 6 parent compounds) and paraben-metabolites (Sigmametabolites = 4 metabolites) w

185 ein, benzophenone-3, bisphenol A, the sum of parabens (methyl, ethyl, and propyl parabens), 2,5-dichl

186 oposed for the quantitative determination of parabens (methyl, ethyl, propyl and butyl paraben) in di

187 omarker concentrations (butyl paraben, ethyl paraben, methyl paraben [MP], and propyl paraben [PP]) a

188 ,4-dichlorophenol, 2,5-dichlorophenol, butyl paraben, methyl paraben, propyl paraben, benzophenone-3,

189 ration in vitro via ERalpha, suggesting that parabens might be active at exposure levels not previous

190 ommon allergens were fragrance mix (n = 87), paraben mix (n = 75), and tocopherol (n = 74).

191 he highest quartile of female urinary methyl paraben (MP) concentrations relative to the lowest refle

192 ations (butyl paraben, ethyl paraben, methyl paraben [MP], and propyl paraben [PP]) and asthma attack

193 ingredients [diethyl phthalate (DEP), methyl paraben (MPB), and triclosan] and urine and serum concen

194 mass spectrometry was developed to determine parabens, musks, antimicrobials, UV filters, and an inse

195 Increasing concentrations of parabens on the cytoplasmic side of excised patches shif

196 describe effects of ethyl, propyl, and butyl parabens on the gating of the bacterial mechanosensitive

197 centrations (phenols, phthalate metabolites, parabens, or triclocarban) from at least 1 time point in

198 s and females, respectively, including PFAS, parabens, organic UV-filters, plastic additives, antimic

199 en (B-PB), methyl paraben (M-PB), and propyl paraben (P-PB).

200 with lower FEV(1)%: copper (p=0.041), ethyl-paraben (p=0.029), five phthalate metabolites (mono-2-et

201 icrobial EDCs triclosan and propyl and butyl parabens (P </= .04).

202 Parabens (p-hydroxybenzoic acid esters), bisphenols, ben

203 eriments suggested that the more hydrophobic parabens partition more strongly into the lipid and exer

204 compared with the lowest quartile of methyl paraben, paternal concentrations in the second quartile

205 thalate esters (PEs), bisphenol A (BPA), and parabens (PBs), which are used in numerous consumer prod

206 Analytes included parabens, phthalates, bisphenol A (BPA), triclosan, etha

207 insecticides, organophosphate esters (OPEs), parabens, phthalates/alternative plasticizers, and polyc

208 Laboratory animal studies have shown that parabens possess weak estrogenic activity.

209 hyl paraben, methyl paraben [MP], and propyl paraben [PP]) and asthma attacks and emergency departmen

210 pressure of 35 mN/m, ethyl, propyl, or butyl paraben present in the subphase at 1 mM increased the su

211 The widespread exposure of humans to parabens present in personal care products is well-known

212 We detected total and free BPA, butyl paraben, propyl paraben, and methyl paraben in 100% of s

213 l, 2,5-dichlorophenol, butyl paraben, methyl paraben, propyl paraben, benzophenone-3, bisphenol A, an

214 Methyl paraben (MeP), propyl paraben (PrP), BADGE.2H(2)O, and BADGE.HCl.H(2)O were th

215 en (ETPB), methyl paraben (MEPB), and propyl paraben (PRPB)], and triclocarban in 760 urine samples c

216 f their four transformation products (Sigma4 Parabens) ranged from 0.47 to 839 ng.

217 l concentrations (Sigmaparabens; sum of five parabens) ranged from below the limit of quantitation to

218 37 and 31.0 mug/kg-bw/day for phthalates and parabens, respectively, for adult females.

219 urinary levels of one LMW phthalate and two parabens, respectively, when compared to children withou

220 Parabens showed their highest concentrations for fresh-m

221 The total amount of the sum of six parent parabens (Sigma6 Parabens) leached from teethers ranged

222 e median respective concentrations of sum of parabens (Sigmaparabens = 6 parent compounds) and parabe

223 We present evidence that paraben/sorbate induction of EPA6 expression involves bo

224 Eight paraben species were quantified in maternal urine obtain

225 Neither of the parabens strongly affects the rate of recovery and does

226 To achieve this, the paraben substituted cyclotetraphosphazene compounds have

227 The sum concentrations of six parabens ( summation operatorPBs) in sludge (geometric m

228 fits of the methodology are demonstrated for paraben test solutes and for phenolic compounds in a blu

229 are an important source of human exposure to parabens; the contribution of PCPs to phthalate exposure

230 ake (EDI; ng/kg of body weight (bw)/day)) of parabens through food ingestion.

231 onception urinary chemical concentrations of parabens, triclosan and triclorcarban in relation to TTP

232 ine-disrupting chemicals such as phthalates, parabens, triclosan, and benzophenone-3 (BP-3) for adole

233 les were analyzed for phthalate metabolites, parabens, triclosan, and BP-3 using high-performance liq

234 s that are labeled to be free of phthalates, parabens, triclosan, and BP-3, can reduce personal expos

235 In cross-sectional studies triclosan and parabens, ubiquitous ingredients in personal care and ot

236 des under ion-exchange conditions and propyl paraben under reversed-phase conditions.

237 urine collection strongly predicted MEP and paraben urinary concentrations.

238 The EDIs of parabens via dust ingestion were 5-10 times higher in ch

239 Ethyl-paraben was associated with increased asthma rate [hazar

240 Perinatal exposure to certain parabens was associated with gut microbiota alpha- and b

241 n contrast, the largest percent increase for parabens was associated with the use of suntan/sunblock

242 The estrogenic activity of parabens was considerably reduced as the parent parabens

243 , theoretical plates, and drift times of the parabens were also evaluated based on the direct interfa

244 These parabens were also measured in breast milk samples colle

245 abens was considerably reduced as the parent parabens were degraded into 4-hydroxybenzoic acid via hy

246 In this study, nine phthalates and six parabens were determined in 170 PCPs (41 rinse-off and 1

247 concentrations of phthalate metabolites and parabens were determined, and children were genotyped fo

248 Parabens were found in approximately 40% of rinse-off pr

249 Increases in MEP and parabens were generally greater with PCP use within 6 h

250 Butyl- and benzyl-parabens were less frequently detected.

251 six parabens and four common metabolites of parabens were measured in 121 tissue samples from eight

252 The effects of both parabens were predominant in children without a history

253 the nano/microfibrous composite sorbent, the parabens were retained.

254 vels of the antimicrobial EDCs triclosan and parabens were significantly associated with allergic sen

255 on, while concentrations of BPA, 24-DCP, and parabens were similar.

256 Methyl-, ethyl-, and propyl-parabens were the predominant compounds, accounting for

257 ermal intake doses (sum of all phthalates or parabens) were calculated to be 0.37 and 31.0 mug/kg-bw/

258 disrupting chemicals, such as phthalates and parabens, which are commonly found in cosmetics, and the

259 Parabens, which have known antimicrobial properties, mig

260 al weight, and benzophenone-3 and the sum of parabens, which were positively associated with this out

261 Parabens, widely used as preservatives in cosmetics, foo

262 Parabens with different side chain structures had differ

263 In recent years, certain phenols and parabens with known adverse health effects are being reg

264 The SDFsC preferentially degraded the parabens with relatively long alkyl or aromatic side cha

265 benzophenone-3 (BP-3), triclosan (TCS), and parabens with serum total testosterone (TT) levels in ch

266 of EDC mixtures (i.e., phthalates, phenols, parabens) within SES groups, defined using k-modes clust