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1 patch area and connectivity (area-isolation paradigm).
2 es questions not addressed by this bacterial paradigm.
3 rs, thus contributing to the Power-of-Things paradigm.
4 etabolic modulation as a promising treatment paradigm.
5 nd electrophysiology during a visual oddball paradigm.
6 addition to the glaucoma surgical treatment paradigm.
7 gative disease eluding the classic monogenic paradigm.
8 eta-thalassemia, a hemoglobin disorder, as a paradigm.
9 ial to challenge the one donor-one recipient paradigm.
10 ial development does not completely fit this paradigm.
11 rter duty cycles when delivered in a blocked paradigm.
12 by using the TraA cell surface receptor as a paradigm.
13 led statistically; the so-called "brain-age" paradigm.
14 ted a proteomic analysis to investigate this paradigm.
15 in the richer rational framework of the new paradigm.
16 ough the prevailing deep targeted sequencing paradigm.
17 ous materials, beyond the current dispersion paradigm.
18 at is observed in other experimental disease paradigms.
19 cit task compared with passive comprehension paradigms.
20 P-1 alters behavioral plasticity in multiple paradigms.
21 plified by psychodynamic, DSM/ICD, and HiTOP paradigms.
22 greatly facilitated by microglial depletion paradigms.
23 re, I describe the bases for these shifts in paradigms.
24 odels and standardization of opioid exposure paradigms.
25 item, as assessed by different false-memory paradigms.
26 ditional new compound families and signaling paradigms.
28 f drinks consumed during an alcohol drinking paradigm (ADP) before and after 1 week of supervised 100
30 a large sample (N = 72) using an established paradigm and a preregistered protocol, we found that TMS
32 introduce such a method within the Bayesian paradigm and apply it to anonymized mobile call detail r
33 e influenced by the selected neuromodulation paradigm and arguably also the prior experience of the p
34 use a noninvasive and reversible deprivation paradigm and converging neural and behavioral approaches
35 inic challenge central tenets of the current paradigm and demonstrate that our understanding of the R
38 roelectronics but also they are an important paradigm and model system to study the intricacies of th
39 es de la Reina may preserve the oligotrophic paradigm and the metabolic dependence of the community o
40 naerobic" peroxisomes that shift the current paradigm and turn attention to the reductive evolution o
41 ultiple experimental approaches into pathway paradigms and discuss future prospects for disease-subty
42 n auditory cortex for a number of behavioral paradigms and mammalian species, less is known about how
45 ranger, being exposed to a fear conditioning paradigm, and (2) the subsequent fear extinction process
46 eCRF modulation using a reverse correlation paradigm, and found three principal eCRF mechanisms: tun
47 a in the context of the writer-reader-eraser paradigm, and progress toward ascribing regulatory signi
48 with unique illness trajectories, treatment paradigms, and potential for curability, which affect pa
50 e we used Magnetoencephalography in a memory paradigm assessing correct rejection (CR) of lures, item
51 muli were presented in the classical oddball paradigm at jittered ISI (0.8-1.2 s), neural responses i
52 inked with spatial synchrony, the prevailing paradigm being that populations with cyclic dynamics are
55 generally follow the multi-instance learning paradigm by viewing each gene as a bag and the spliced i
58 dapting the random-dot motion discrimination paradigm, classically used in primate studies, to larval
59 n electrode and battery designs, stimulation paradigms, closed-loop and on-demand stimulation, and se
61 y, a fast periodic visual stimulation (FPVS) paradigm coupled with EEG was used to assess the ability
64 will enable us to design more valid research paradigms, develop more effective management strategies,
66 ures across locations, and the three novelty paradigms diverge widely in their climate change vulnera
70 ontrols (HC) underwent a symptom provocation paradigm during which subjects watched video clips of sp
71 gical anxiety depends on the availability of paradigms effective in inducing anxiety in a simple, con
73 However, in striking counterpoint to the paradigm established by numerous human and murine exampl
76 th their tetraradial symmetry, offer a novel paradigm for addressing patterning mechanisms during reg
79 r (DTG)-based dual therapy is becoming a new paradigm for both the initiation and maintenance of HIV
81 molecular dynamics simulations, providing a paradigm for connecting protein filament structure and m
83 designable structure space and offers a new paradigm for designing proteins with tunable geometries
84 ne Nematostella vectensis as an experimental paradigm for developmental patterning across distinct li
86 understanding of JAM in cancer and provide a paradigm for exploring additional roles of TJ proteins.
89 ling via other TLRs, suggesting a convergent paradigm for fine-tuning macrophage inflammatory respons
91 nd colleagues in this issue introduces a new paradigm for generating new mouse models for melanoma re
92 s under physiological settings and present a paradigm for how such events could occur across developm
93 infectious disease are quickly forming a new paradigm for how we understand and model host-pathogen r
95 ur findings suggest a new, to our knowledge, paradigm for lncRNA-mediated modulation of lymphocyte ac
96 These considerations create a generalized paradigm for M-M bonding in the transition-elements peri
102 though this process has been an experimental paradigm for reproduction and sperm chemotaxis studies,
103 Autonomous experimentation is an emerging paradigm for scientific discovery, wherein measurement i
104 ential to significantly change the treatment paradigm for severe hemophilia A by providing optimal pr
106 vation and G protein coupling, and provide a paradigm for studying membrane protein-lipid interaction
109 tide synthase (PKS) machinery, expanding the paradigm for the biosynthesis of quinolone-gamma-lactam
111 This research accounts very well for the "paradigm for the electron requirements of clusters", in
113 embranes, exemplified by signalosomes, are a paradigm for the regulation of many membrane signaling p
114 and reproductive processes is forming a new paradigm for the study of within-host pathogen evolution
116 this logistical challenge, we propose a new paradigm for trace contaminant monitoring based on dry p
118 The Caenorhabditis elegans vulva has been a paradigm for understanding many aspects of organogenesis
120 more coexisting phases has emerged as a new paradigm for understanding subcellular organization, pre
122 UV-4B-derived compounds may alter treatment paradigms for acute viral disease through development of
124 s a springboard for the development of novel paradigms for genetic networks that will help develop mu
125 SAGA coactivator complex are generating new paradigms for how the components of these complexes func
127 an-inspired, discrimination-based behavioral paradigms for studying selective visuospatial attention
129 plinary medicine to FH care and can serve as paradigms for the prevention of premature atheroscleroti
131 and genome editing, which are switching the paradigm from bottom-up discovery and testing of individ
135 large phenotypic effects in contrast to this paradigm, genome-wide population genetic estimates have
136 sider the limits of the current 'myocentric' paradigm given the wide-ranging array of impacts that ex
141 e compounds identified through our screening paradigm have the potential to be used as prophylactics
142 oderate-intensity continuous training (MICT) paradigms have been shown to confer vascular benefits tr
146 llic Mn/Fe proteins represent a new cofactor paradigm in bioinorganic chemistry and pose countless ou
148 a differential pavlovian threat-conditioning paradigm in eight patients with a bilateral vmPFC lesion
149 loped a stress-enhanced fear learning (SEFL) paradigm in inbred mice that produces PTSD-like characte
152 les are established as a potentially general paradigm in photoredox Ni-catalyzed carbon-heteroatom cr
153 macroscopic order and patterns is a central paradigm in systems of (self-)propelled agents and a key
154 nd act as further validation of a burgeoning paradigm in targeted therapy, namely the disruption of c
158 cdysone production, creating an experimental paradigm in which the wing stops growing at the correct
159 participants underwent an emotion regulation paradigm in which they either watched negative or neutra
160 findings establish an ethologically relevant paradigm in zebrafish for studying how the brain is shap
161 It also highlights some of the emerging paradigms in cancer diagnosis that may transform the dia
162 generative demands, SCs often follow similar paradigms in communicating with their microenvironmental
163 two exploratory approach-avoidance conflict paradigms in mice: the elevated zero maze and open field
164 nges facing current treatment and prevention paradigms in the clinic, there is an increasing push for
165 of diagnosis, risk stratification and modern paradigms in the treatment and management of patients wi
166 ated onto a substrate is one of the simplest paradigms in which angular symmetry-breaking assemblies
167 -contingent simulated visual field (VF) loss paradigm, in which participants experienced a variable m
171 mately 3 weeks later, they completed an fMRI paradigm involving extinction recall, in which they rate
174 paired with aging and establish that the OUL paradigm is an effective, sensitive method of assessing
178 in use because the optimal patient transfer paradigm is highly dependent on local geography and hosp
179 odel-informed drug discovery and development paradigm is now well established among the pharmaceutica
181 To focus on specific cell types, the current paradigm is to physically isolate subsets of interest pr
183 he gastrointestinal stromal tumour treatment paradigm, it was decided by the sponsor's medical direct
184 been previously shown to be recruited by VWM paradigms, it is unclear whether any portion of cerebell
185 tic rodent model of ELS, the limited bedding paradigm (LB) between postnatal days 1-10, we previously
188 the continuous exploration of novel storage paradigms, materials, and devices with increasing data d
191 ruggable susceptibilities, thus updating the paradigm of adaptive resistance development in an isogen
192 should be aligned with anatomy in the modern paradigm of AEG management and design of clinical trials
196 g of endo sulfatase activity questioning the paradigm of how the 'sulfation problem' is handled by th
197 its in learning acquisition in a touchscreen paradigm of intermediate pattern separation or MWM platf
198 /KIT inhibitor midostaurin has validated the paradigm of KIT inhibition in advSM, and the efficacy an
199 Our results provide proof-of-concept for a paradigm of microbially-derived biosensors adaptable to
200 in the nervous system to inform a major new paradigm of neuroimmunology and therapeutic development
201 a-cage hierarchy in male mice, but also as a paradigm of novel territorial competition in animals fro
202 o circumvent these constraints, we realize a paradigm of phonon trapping using mechanical bound state
203 in the conventional magnetization-switching paradigm of pinning-type magnets, suggesting a critical
205 transitions within a novel, non-homeostatic paradigm of sleep regulation.SIGNIFICANCE STATEMENT We s
208 es during this crisis challenges the current paradigm of traditional drug discovery and development,
220 the social defeat or vicarious defeat stress paradigms-procedures that mediated a depression-related
221 evolutionarily conserved signal transduction paradigm, providing mechanisms for rapid receptor-to-nuc
222 ss a wide variety of tasks and computational paradigms, ranging from regression to image classificati
223 d provides evidence contrary to the existing paradigm regarding the biological role of computationall
224 rogress almost entirely rests on this single paradigm, resulting in a very specialized knowledgebase
227 or self-powered sensor, but also presents a paradigm shift for large-scale energy harvesting by TENG
228 ding of the pathophysiology of depression, a paradigm shift from monoamine to glutamatergic neurotran
232 pressant effects of ketamine has 1) led to a paradigm shift in our perception of what is possible in
233 iplexed "QCR-on-chip" technology, bringing a paradigm shift in speed, accessibility and affordability
238 in ASD as a monolithic deficit and suggest a paradigm shift that deconstructs BM into distinct levels
239 rs are poised to play an important role in a paradigm shift that fundamentally challenges the current
241 improvements in pain treatment may require a paradigm shift toward more personalized approaches.
244 atory syndrome in children (MIS-C) has had a paradigm-shifting effect on the perception of severe acu
245 ophosphatemic rickets, has also driven major paradigm shifts in our understanding of the pathophysiol
246 Therapeutic strategies and experimental paradigms should operate under the assumption that trunc
248 voluntary, gelatin oral self-administration paradigm that allowed male and female mice to consume De
250 te, the field has lacked a simple behavioral paradigm that can measure whether original and updated i
251 regulatory loop represents a novel signaling paradigm that connects autocrine and endocrine signaling
253 thin these three frameworks to move toward a paradigm that formulates RNA-targeting questions at the
255 mune functions, which contradict the current paradigm that microglia are the main immune effector cel
257 ise followed by 1 week of 7 kHz tone pips, a paradigm that results in the functional over-representat
265 arvation in E. coli These results serve as a paradigm to demonstrate that bacterial adaptation to lon
266 devised an ethologically inspired behavioral paradigm to directly test the hypothesis that echolocati
272 works and assess the capacity of each stress paradigm to recapitulate the transcriptional organizatio
273 applicability of this marine reserve network paradigm to riverine biodiversity and inland fisheries r
274 ve of an acute respiratory distress syndrome paradigm to see if any specific mechanical ventilation s
275 cell persistence after radiation provides a paradigm to study mechanisms that may contribute to unan
276 describe and test a more ecologically-valid paradigm to study the brain response to bladder filling
277 tegrate these new findings with the previous paradigm to synthesize a current molecular and cellular
278 times were recorded using a visual detection paradigm to two types of centrally-presented stimuli.
279 ited for current tissue-specific therapeutic paradigms to augment the endogenous osteogenic cells for
280 uce motion artifacts, and limit experimental paradigms to isolated subjects in open, two-dimensional
284 both chemogenetics and a volitional behavior paradigm, we identified a core set of brain endothelial
285 sing a dramatic one-shot perceptual learning paradigm, we observed that prior knowledge results in sh
286 e, using an acute restraint-tailshock stress paradigm, we report that both authentic and transmitted
287 347) classic performance-morphology-fitness paradigm, we tested for pre- to post-fledging carryover
289 properties of TPC2 and they establish a new paradigm whereby a single ion channel mediates distinct,
290 , wild-type mice to distinct chronic jet-lag paradigms, which showed that long-term circadian misalig
292 tarianism and common-sense morality, and new paradigms will be necessary to investigate other key asp
293 ole central actors and toward a more complex paradigm with B cells having an essential role in both t
296 decade has witnessed a fundamental change of paradigm with the discovery that the vascular endotheliu
297 ynamics in engineering studies is a powerful paradigm with which to engineer the next generation of d
298 onnected words than to sentences, and (2) in paradigms with an explicit task compared with passive co