ライフサイエンスコーパス: paralogue

1 able databases) and 49% are gene duplicates (paralogues).

2 protein gene RPL22A, but not its unenriched paralogue.

3 ponds with a key, conserved eukaryotic Rad51 paralogue.

4 gment cell patterning not seen in the second paralogue.

5 B. napus with the participation of ABI1-like paralogues.

6 vars, rather than expression of specific FLC paralogues.

7 nce and functional divergence of the BnaABI1 paralogues.

8 nBank and the large number of highly similar paralogues.

9 s, but in S. maritima is encoded by over 100 paralogues.

10 Most teleost fish possess two MSTN paralogues.

11 tic conservation with respect to their human paralogues.

12 n function between the closely related SEC23 paralogues.

13 ects in OXS2 and three of the four OXS2-like paralogues.

14 ncluding RAD51-related proteins termed Rad51 paralogues.

15 ation with immune cell types compared to its paralogues.

16 Multiple myosin II paralogues accumulate at mammalian epithelial cell-cell

17 S domain-containing protein ENL, but not its paralogue AF9, is required for disease maintenance in ac

18 rst reported comprehensive analysis of Hsp90 paralogue affinity and selectivity in the clinical Hsp90

19 The Mdm4 (alias MdmX) oncoprotein, like its paralogue and interaction partner Mdm2, antagonizes the

20 FLC expression during cold treatment between paralogues and accessions.

21 d the zebrafish genome to identify potential paralogues and confirmed their homology, bringing the to

22 n IPTL, as shown by the accumulation of LC3B paralogues and diminishment of lysosome associated membr

23 , has revealed that these proteins are Rad51 paralogues and mediate DNA binding of this complex.

24 s, which are the most diverged region of the paralogues and probably evolved independently after a ge

25 ized non-conserved functional domains in ATL paralogues and show that the ATL interactome is profound

26 protein-coupled receptors consists of 10 FZD paralogues and Smoothened (SMO).

27 monstrate correlation between Notch and Mef2 paralogues and support the notion that Notch-MEF2 synerg

28 suggesting functional coupling between Cas6 paralogues and their downstream effector complexes.

29 SM/type III-A and CMR/type III-B), five Cas6 paralogues and two different CRISPR-repeat families (AB

30 a suggest the involvement of two other mak-1 paralogues and two orthologues of p38 MAP kinase.

31 residues in evolutionarily related proteins (paralogues) and, where appropriate, transfers annotation

32 agonists that selectively target each Jagged paralogue, and determine a crystal structure that explai

33 ust and reproducible sets of orthologues and paralogues, and enriched views of gene expression and ge

34 including their stoichiometry, compositions, paralogues, and posttranslational modifications.

35 ed sequence heterogeneity in mammalian Notch paralogues, and should allow the development of paralogu

36 lt of the expression of multiple Kir2 family paralogues, and the inwardly rectifying conductance cont

37 The functionally conserved paralogues appear to target to compartments associated w

38 r because of the observation that various PC paralogues are activated at different organellar pH valu

39 In human and primates, ATAD3 paralogues are encoded by three genes (ATAD3A, 3B and 3C

40 at is found in budding yeast where the RAD51 paralogues are fully dependent on the SRS2 anti-recombin

41 n supernumerary chromosomes and whether EBR1 paralogues are functional is currently unknown.

42 Because the functionally diversifying paralogues are still closely related to and derived from

43 ARID3B has two closely related paralogues, ARID3A and ARID3C.

44 an contains approximately the same number of paralogues as found in the two soybean homeologues combi

45 itration calorimetry studies show that these paralogues bind the product of the methylation reaction,

46 only the major binding modes that relay pan-paralogue binding or, conversely, paralogue selectivity,

47 ession pattern of two evolutionarily distant paralogues, BnaA01.ABI1.a and BnaC07.ABI1.b in B. napus

48 a, Interference hedgehog (Ihog) or its close paralogue Brother of Ihog (Boi) forms a receptor complex

49 ling tight co-expression between the IGF-IRa paralogues, but expression divergence comparing IGF-IRa

50 ared the physical binding properties of each paralogue by surface plasmon resonance and determined th

51 Inhibition of TTBK paralogues by RNA interference (RNAi) revealed a specifi

52 The caspase-8 paralogue c-FLIP is a good candidate for a molecular rhe

53 The conformations of C4b and its paralogue C3b are shown to be remarkably conserved, sugg

54 A TsdA paralogue (C8j_0040), lacking the unusual His-Cys haem l

55 etwork identified a pair of redundant kinase paralogues called Ark1 and Prk1.

56 ome duplication, which suggests that ancient paralogues can remain in the same regulatory networks fo

57 is a key effector in abscission, whereas its paralogue, CHMP4C, is a component in the abscission chec

58 that in zebrafish two subfunctionalized cmas paralogues co-exist, we introduce a novel and unique mod

59 CXXC motif are replaced by their motif-free paralogues, collectively called C- r-proteins.

60 that HELQ interacts directly with the RAD51 paralogue complex BCDX2 and functions in parallel to the

61 us proteins, evolved from a more ancient two-paralogue complex because of a gene duplication that was

62 pression of the endogenous MAF2 gene and its paralogues, confounding functional assessment.

63 The transcripts of these clustered paralogues contribute to a large majority of the mRNA po

64 In contrast, the paralogue Cr-AGO2 is nuclear enriched and exclusively bi

65 KIX domain of the histone acetyltransferase paralogues CREB-binding protein (CBP) and E1A-binding pr

66 terrelationship between the three NMCP1-type paralogues (CRWN1, 2, and 3) and the lone NMCP2-type par

67 es (CRWN1, 2, and 3) and the lone NMCP2-type paralogue, CRWN4.

68 Finally, we show that Dchs1, and its paralogue Dchs2, function in a partially redundant fashi

69 Relative expression of the EBR1 paralogues depends on growth conditions and on the prese

70 These findings indicate that different SUMO paralogues determine the fates of WT and mutant CFTRs, a

71 Here we show in mice that different NAIP paralogues determine the specificity of the NLRC4 inflam

72 Here, we study how these multiple FLC paralogues determine vernalization requirement as a syst

73 aeruginosa genome encodes a closely related paralogue DksA2 that lacks the Zn-finger motif.

74 ot observed acetylation of Poliota's closest paralogue, DNA polymerase eta (Poleta), with which Polio

75 acking Dcx and/or its structurally conserved paralogue, doublecortin-like kinase 1 (Dclk1), show impa

76 ABI1 gene orthologue and Brassica napus gene paralogues encoding protein phosphatase 2C (PP2C, group

77 irst inhibitors selective for ERAP1 over its paralogues ERAP2 and IRAP.

78 Eukaryotic-specific ribosomal protein paralogues eRpL22 and eRpL22-like are essential in devel

79 Conversely, the ESX-1 paralogue EspG(1) interacted with a PE/PPE couple secret

80 blished with what degree of specificity CheR paralogues exert their activity.

81 These paralogues exhibit sequence and copy number variation am

82 epithelia, as well as a repertoire of genome paralogues expressed complimentarily in each organ.

83 To determine how tissue-specific septin paralogue expression may shape core heteromer repertoire

84 chemical function of its yet uncharacterized paralogue FAM173A.

85 plasmic domain 6 amino acids longer than its paralogue, Fcgr3.

86 ic protein FlaG and the association with its paralogue FlaF are essential for archaellation and motil

87 indicated that expression of two fibronectin paralogues, fn1 and fn1b, are induced by injury in epica

88 In zebrafish, there are 2 paralogues for adtrp (i.e., adtrp1 and adtrp2).

89 These SUMO paralogues form polychains, which are recognized by the

90 GOLPH3L is a GOLPH3 paralogue found in all vertebrate genomes, although prev

91 l locus shared with the dual TOR1A and TOR1B paralogues found in tertrapods.

92 heniformis and Bacillus pumilus as well as a paralogue from B. subtilis called YweA.

93 the kinetic properties of two different Cas6 paralogues from S. solfataricus.

94 establish that salmonids retain two IGF-IRa paralogues from ssWGD and a single IGF-IRb copy.

95 Individual AdoMetDC-SpdSyn fusion protein paralogues from Tetrahymena exhibit undetectable AdoMetD

96 proteins in Paramecium cells, we found that paralogues from the two most recent whole-genome duplica

97 and I304N mutant FMRP isoforms and the FMRP paralogues FXR1P and FXR2P (also known as FXR1 and FXR2)

98 et al. investigate the role of Gata6 and its paralogue Gata4 in mouse embryonic pancreas and show tha

99 ry microRNAs and temporal divergence of gene paralogues generated in the teleost genome duplication.

100 In T. brucei, four putative RAD51 paralogue genes have been identified by sequence homolog

101 The paralogue GLO1, from which GLO2 arose by duplication, ha

102 an Golgi reassembly stacking protein (GRASP) paralogues, GRASP55 (GORASP2) and Rab8a.

103 ttempts of direct inhibition of N-MYC or its paralogues has led to the conclusion that this protein i

104 We conclude that it is unlikely that the paralogues have a function in primary myogenesis.

105 ion and ablation of nonmuscle myosin 2 (NM2) paralogues have demonstrated their importance for contac

106 Our data demonstrate that Survivin paralogues have different characteristics of phosphospec

107 bstitute fully for eRpL22 function, and that paralogues have functionally distinct roles, not yet def

108 However, the specific roles of the NM2 paralogues have not been systematically studied.

109 ic clones showed that the effects that these paralogues have on proliferation serve to promote cell c

110 Mutant analysis indicates that the paralogues have shared, non-redundant roles in regulatin

111 ound that it includes a cohesive outgroup of paralogues (herein coined LoaP), which are often positio

112 Using zebrafish, we found that the HNF1beta paralogues hnf1ba and hnf1bb, which encode homeodomain t

113 expression assays reveal that Hoxb4 and its paralogue Hoxd4 are necessary and sufficient for cell se

114 l extension (CTE) by contrasting HP1a to its paralogue, HP1b.

115 uctures of tau55-HPD and its closely related paralogue Huf and used in silico docking methods to iden

116 1b has been duplicated twice, yielding three paralogues: Ifit1, Ifit1b, and Ifit1c.

117 Different IL-4/13 paralogues (IL-4/13 A and IL-4/13B) exist in teleost fis

118 omain and compared it to its closely related paralogue in ATAD2.

119 er, the specific cells expressing this Notch paralogue in the mammary gland remain unknown.

120 switching from the clag 3.2 to the clag 3.1 paralogue in vitro.

121 ssed the in vivo activities of SCCRO and its paralogues in cullin neddylation.

122 or understanding the role of the human RAD51 paralogues in Fanconi anaemia and cancer predisposition.

123 The exclusive presence of highly conserved paralogues in higher organisms led us to assess whether

124 There are 13 confirmed septin paralogues in mammals, which may be ubiquitous or tissue

125 .graminearum and other fungi but as multiple paralogues in pathogenic F.oxysporum strains.

126 The relative sparsity of paralogues in sequence space suggests that new insulated

127 ay in dicots may have functionally redundant paralogues in switchgrass and therefore require further

128 th nuclear localization signal (NLS)-bearing paralogues in the NMCP1-clade was discounted based on re

129 trand invasion, however, the function of the paralogues in the process of homologous recombination is

130 tentially broad role for RNase G, an RNase E paralogue, in the trimming of 5'-monophosphorylated ends

131 The conserved budding yeast Rad51 paralogues, including Rad55, Rad57, Csm2 and Psy3 are in

132 We identified seven Wnt paralogues, including the major PCP regulator Wnt5a, whi

133 rlY/- mice, where the lethal deletion of the paralogue Inpp5b was rescued by human INPP5B insertion,

134 We also show that the T. brucei RAD51 paralogues interact, and that the complexes they form ma

135 that requires Arg67, a residue conserved in paralogues, IRAK-1 and 3(M).

136 dies suggest that silencing of either clag 3 paralogue is associated with the enrichment of specific

137 sociated ClpX must recruit ClpP, for which a paralogue is not duplicated within any of the nitrogen f

138 A distinguishing feature of these paralogues is an H-to-R change in an amino acid that int

139 esults show that the presence of these three paralogues is associated with different activities, both

140 The Shu complex, which contains RAD51 paralogues, is involved in the decision between homologo

141 vated protein kinase Slt2p, its pseudokinase paralogue, Kdx1p, and an associating transcription facto

142 k-out mouse models for both Kiaa0319 and its paralogue Kiaa0319-like reported effects in the auditory

143 lso report that a high dose of either of two paralogue kinases, Kin1 and Kin2, overcomes the defectiv

144 n of both the two AG and two SEEDSTICK (STK) paralogues lacked both seeds and associated seed hairs.

145 esults in an increased reliance on the FabHb paralogue leading to a greater proportion of straight ch

146 ucing a single historical mutation from each paralogue lineage into the resurrected ancestral protein

147 Mammals express three paralogues: lipins 1, 2, and 3.

148 Gain/amplification of MIR17HG and its paralogue loci was observed in 50% of adult-mBL.

149 d the possibility that additional JAM family paralogues may also function in muscle development.

150 circle accumulation, suggesting that the two paralogues mediate overlapping and nonredundant function

151 on assays show that CheR2, but not the other paralogues, methylates the McpS and McpT chemotaxis rece

152 In vertebrates, two mitofusin paralogues, Mfn1 and Mfn2, are required for efficient mi

153 nnotation errors, nomenclature variation and paralogues; moreover, GenBank's structure and tools are

154 In contrast, TRIM family paralogues most closely related to TRIM5 did not.

155 Vertebrate SoxE paralogues, most notably Sox9/10, are essential for NC i

156 higher order mutants of MUR4 with its three paralogues, MURL, DUR, MEE25, reveals that the paralogue

157 transcription factor FOUR LIPS (FLP) and its paralogue MYB88 regulate terminal divisions during stoma

158 A third paralogue, Mycl1, is dispensable for normal embryonic de

159 RNAi against the NDE1 paralogue NDEL1 has no such effects.

160 Here we show that the NPR1 paralogues NPR3 and NPR4 are SA receptors that bind SA w

161 The transaldolase paralogue NQM1 and the transcription factor VHR1 interac

162 Genetic ablation of Nsd1 and its paralogue Nsd2 in mouse cells results in a redistributio

163 previously reported role of Nup157, and its paralogue Nup170, in chromatin organization.

164 TBC1D1), a Rab GTPase-activating protein and paralogue of Akt substrate of 160 kDa (AS160), has been

165 The paralogue of Alx1, Alx4, was not functionally interchang

166 Gene expression studies identified MtLAX2, a paralogue of Arabidopsis (Arabidopsis thaliana) AUX1, as

167 We also show that iBraf, a paralogue of Braf35, forms heterodimers with Braf35.

168 protease 50 (TSP50) and the testis-specific paralogue of CCCTC-binding factor, BORIS (brother of the

169 By contrast, the germ-cell-specific paralogue of CTCF, BORIS (brother of the regulator of im

170 efect, is to modulate utrophin, a functional paralogue of dystrophin, able to compensate for the prim

171 phin expression, a structural and functional paralogue of dystrophin, can successfully prevent the dy

172 hin with increases of utrophin, an autosomal paralogue of dystrophin.

173 nants of PC activation, we analyzed PC1/3, a paralogue of furin that is activated at a pH of approxim

174 However, POLRMT also interacts with the paralogue of h-mtTFB2, h-mtTFB1, which is a 12S ribosoma

175 ein, which suggests that NS1 is a structural paralogue of hRSV matrix (M) protein.

176 ORP4 (OSBP2) is a closely related paralogue of OSBP, but its function is unknown.

177 and also inhibit the activity of RNase G, a paralogue of RNase E.

178 of SLC25A51 or SLC25A52 (a nearly identical paralogue of SLC25A51) increases mitochondrial NAD(+) le

179 protein (TBP)-associated factor 7l (Taf7l; a paralogue of Taf7) and TBP-related factor 2 (Trf2) are c

180 Here we report that TAF7L, a paralogue of TFIID subunit TAF7, is enriched in adipocyt

181 As the endoplasmic reticulum paralogue of the cytosolic HSP90, gp96 (GRP94, HSP90b1)

182 Blo t 21 is a paralogue of the group 5 allergen, Blo t 5, a major alle

183 SYCP2L is a paralogue of the synaptonemal complex protein SYCP2 and

184 The SAS6-like (SAS6L) protein, a truncated paralogue of the ubiquitous basal body/centriole protein

185 hiamin pyrimidine synthase (thiC) revealed a paralogue of thiC (bzaF) clustered with anaerobic vitami

186 s are only partially conserved in C2CD2, the paralogue of TMEM24 primarily expressed in nonneuronal t

187 The recently identified paralogue of XRCC4 and XLF (PAXX) factor has homology to

188 demonstrate the retention of two functional paralogues of csf1r in zebrafish.

189 4(yeast)/Pelota(mammals) and Hbs1, which are paralogues of eRF1 and eRF3, are implicated in these pro

190 iRNA precursors, and previously unrecognized paralogues of functionally important miRNA families (e.g

191 Signatures of subfunctionalisation of paralogues of Hox genes are revealed in the appendages o

192 ralogues, MURL, DUR, MEE25, reveals that the paralogues of MUR4 also contribute to the biosynthesis o

193 Three paralogues of NudC are known in vertebrates: NudC, NudC-

194 specific Pgp lineage, Pgp-18, as well as two paralogues of Pgp-11 and Pgp-16.

195 ere a comparative analysis of the three CheR paralogues of Pseudomonas putida.

196 cific sublocalization cases with specialized paralogues of tAPX and sAPX.

197 gent of Chagas disease, possesses two unique paralogues of the mitochondrial calcium uniporter comple

198 Plastid paralogues of trafficking-associated proteins potentiall

199 of critical amino acid residues of the four paralogues on mitochondrial Ca(2+) uptake.

200 coactivator CREB binding protein (CBP), its paralogue p300, and the retinoblastoma protein (pRb; als

201 The histone acetyltransferase paralogues p300 and CREB-binding protein (CBP) are key t

202 ve novel salmonid-specific AMPK subunit gene paralogue pairs.

203 NA strands recruit the protein PARP1 and its paralogue PARP2 to modify histones and other substrates

204 roteins interact directly with ATML1 and its paralogue PDF2 and that silencing of both HD-ZIP transcr

205 tivator Yes-associated protein (YAP) and its paralogue PDZ-binding motif (TAZ) with associated declin

206 This observation led us to identify a pelX paralogue, PFL_5533, which we designate here PgnE, that

207 B forms homodimers and heterodimers with its paralogue PHOX2A in vitro, we tested the hypothesis that

208 ing either the POLR3G subunit or the related paralogue POLR3GL.

209 istoyl sequence in SCCRO3, one of four SCCRO paralogues present in humans that localizes to the membr

210 r the evolution of complexity in other multi-paralogue protein complexes.

211 product of RAD51B interacts with that of its paralogue RAD51, which is associated with congenital mir

212 In yeast the two Rad51 paralogues, Rad55 and Rad57, have been shown to be invol

213 The paralogue ratio test (PRT) is a simple, cost-effective m

214 DEFB copy number was determined by paralogue ratio test.

215 urpose of this study was to evaluate whether paralogue ratio tests (PRT) using real-time PCR can accu

216 In this work, we use paralogue ratio tests, microsatellite analysis, read dep

217 RNA-binding motif protein 15 (RBM15) and its paralogue RBM15B, which bind the m(6)A-methylation compl

218 Five paralogues (RecQ1, Bloom, Werner, RecQ4, and RecQ5) are

219 likely that the overlapping roles of the two paralogues released functional constraints on csf1ra, al

220 ge of protists, demonstrating that the Rad51 paralogue repertoire in T. brucei is unusually large amo

221 g mutants in both ecotypes lacking the DELLA paralogues REPRESSOR OF ga1-3 (RGA) and GA INSENSITIVE (

222 d us to assess whether compensation by SCCRO paralogues rescues lethality in SCCRO(-/-) mice.

223 erized the interaction between NUPR1 and the paralogue RING1B in vitro, in silico, and in cellulo.

224 thin the genome in a strain lacking the Rpl8 paralogue RPL8A, demonstrating that the gene targeted fo

225 Missense mutations in the human COPII paralogues SEC23A and SEC23B result in craniolenticulosu

226 es and set the ground for the development of paralogue selective inhibitors.

227 analysis that allows for rationalization of paralogue selectivity and defines not only the major bin

228 relay pan-paralogue binding or, conversely, paralogue selectivity, but also identifies molecular cha

229 tion patterns, and that less closely related paralogues showed evidence of both conservation and dive

230 lear positioning in guard cells, whereas its paralogue SINE2 contributes to innate immunity against a

231 Trypanosoma brucei encodes three paralogue single-protein OSTs called TbSTT3A, TbSTT3B, a

232 Humans have a paralogue, SMN2, whose exon 7 is predominantly skipped,

233 Two smyd1 paralogues, smyd1a and smyd1b, have been identified in z

234 udied the poorly characterized SNX20 and its paralogue SNX21, which contain an N-terminal PX domain a

235 These SUMO paralogue-specific effects of PIAS4 were reproduced in v

236 alogues, and should allow the development of paralogue-specific ligand-blocking antibodies.

237 ar determinants of the bound orientation and paralogue specificity of a SIM are unclear.

238 In some cases, these paralogues specify distinct biochemical and/or functiona

239 and the L. monocytogenes genome contains two paralogues, spxA1 and spxA2 Here, we demonstrate that sp

240 xidative stress requires the activity of two paralogues, SpxA1 and SpxA2.

241 ific splicing regulator Srrm4/nSR100 and its paralogue Srrm3.

242 erminal region (RQC) found in the other RecQ paralogues; such a region consists of a zinc domain and

243 Deletion of IscA and its paralogue SufA results in an E. coli mutant that fails t

244 other protists possess highly divergent XPB paralogues suggesting that XPBs specialized in transcrip

245 Structure-guided mutagenesis of the close paralogue SWEET1 from Arabidopsis identified key residue

246 WT and mutant CFTRs, and they suggest that a paralogue switch during biogenesis can direct these prot

247 om other chromatin remodellers including its paralogue SWR1.

248 ed structure is similar to that found in the paralogue Talin head domain.

249 -43, we knocked out zebrafish Tardbp and its paralogue Tardbp (TAR DNA binding protein-like), which l

250 ls in the presence of low levels of the TatA paralogue TatE.

251 f the xenophagy cargo receptor Ndp52 and its paralogue Tax1bp1, which we demonstrate here to be a bon

252 Yap1 and its paralogue Taz largely control epithelial tissue growth.

253 ATA binding protein (TBP) is replaced by its paralogue, TBPL2 (TBP2 or TRF3), which is essential for

254 e show that downregulation of TCF7L1 and its paralogue TCF7L2 reduces tumor growth in a xenograft mod

255 CUL3(KBTBD8) monoubiquitylates NOLC1 and its paralogue TCOF1, the mutation of which underlies the neu

256 ed by heterodimer formation with an inactive paralogue termed prozyme.

257 that a knockout of the gene for the smaller paralogue, termed XPB-R (R for repair) resulted in viabl

258 T-STAR is a tissue-specific paralogue that regulates the alternative splicing of neu

259 Finally, we document the Rad51 paralogues that are encoded by a wide range of protists,

260 otic cells express transcription factor (TF) paralogues that bind to nearly identical DNA sequences i

261 in vivo, which preferred endogenous SUMO-2/3 paralogues that form poly-chains.

262 2 and RING 1A, which are partially redundant paralogues that together account for the E3 ubiquitin li

263 istent with the Shu complex containing Rad51 paralogues, the methyl methanesulphonate sensitivity of

264 mited use for environmental barcoding due to paralogues, the potential for unidentifiable chimaeras a

265 that Csm2 interacts with Rad51 and the Rad51 paralogues, the Rad55-Rad57 heterodimer and that the Shu

266 cellular roles for these P. aeruginosa SPase paralogues; the role of PA1303 is integrated with the qu

267 that, as predicted for the TcMCU and TcMCUb paralogues, they are composed of two helical membrane-sp

268 ate cell-specific expression of the teashirt paralogue tiptop, which is not normally expressed in lar

269 mental expression affects the ability of one paralogue to compensate for the loss of the other.

270 olic enzyme non-quiescent mutant 1 (NQM1), a paralogue to the pentose phosphate pathway enzyme transa

271 ction pressure has allowed expression of FLC paralogues to diverge, resulting in variation of FLC exp

272 For some genes S. maritima has evolved paralogues to generate coding sequence diversity, where

273 ignaling pathways recruit distinct myosin II paralogues to generate the contractile apparatus at apic

274 ome insulated from each other and from other paralogues to prevent unwanted crosstalk(3).

275 The contribution of PXY and ER paralogues to stem patterning is not known, nor is their

276 rsing out the contribution of the four Hsp90 paralogues to the perceived biological activity with the

277 l element that is recognized by TUT7 and its paralogues, TUT4 (ZCCHC11) and TUT2 (GLD2/PAPD4).

278 a showed differences in the induction of the paralogues under dehydration stress.

279 ma-carboxylation in osteoblasts, whereas its paralogue, VKORC1L1, is dispensable for this function an

280 Two of these paralogues, VPS26A and VPS26B, are expressed in humans.

281 -2/simian immunodeficiency virus (SIV) SIVsm paralogue Vpx, hijack the CRL4(DCAF1) E3 ubiquitin ligas

282 Arabidopsis thaliana VTC2 and its paralogue VTC5 function as GDP-L-galactose phosphorylase

283 The functional divergence between kindlin paralogues was assessed using the sequence swap (chimera

284 is of conserved sequence fingerprints within paralogues, we predicted functional residues and residue

285 hat led to the functional diversification of paralogues, we tracked duplicate retention patterns, exp

286 new inhibitors targeting MraY as well as its paralogues, WecA and TarO.

287 omains are extremely similar, WelLFY and its paralogue WelNDLY exhibit distinct DNA-binding specifici

288 the miR-17 approximately 92 cluster and its paralogues were also highly expressed in ALK(+) ALCL and

289 cmas paralogues were maintained in fishes of the Otocephala c

290 In mammals, 13 septin paralogues were recently shown to assemble into core het

291 inding to histone tails of the human class A paralogue, which has a histidine at this position, is se

292 or the potential function of the human RAD51 paralogues, which are known to be involved in cancer pre

293 nd that Hoxa2/Hoxb2 NC enhancers are ancient paralogues, which diverged in hindbrain and NC activitie

294 t nonmammalian vertebrates have two Survivin paralogues, which we name class A and B.

295 Eukaryotes also possess Rad51 paralogues, whose exact role in recombination remains to

296 The combination of multiple FLC paralogues with different expression dynamics leads to r

297 There are three MII paralogues with distinct biophysical properties expresse

298 s, however, possess two highly divergent XPB paralogues with only the larger being identified as a TF

299 This suggests that EB1 paralogues within one species may interact with overlapp

300 We also show that Mdm1 and its paralogue Ydr179w-a (named Nvj3 in this study) localize