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1 tions of missense alleles of unc-15 (encodes paramyosin).
2  library revealed that UNC-89 interacts with paramyosin.
3 eviously described component of M-lines, and paramyosin.
4 ization of a major thick filament component, paramyosin.
5 oform-specific interaction between MHC A and paramyosin.
6 erhaps through phosphorylation of myosin and paramyosin.
7 he binding of CaGC to native and recombinant paramyosin, 125I-CaGC was used as a binding tracer in SD
8                                              Paramyosin, a myofibrillar protein found only in inverte
9 analysis of normal embryos demonstrated that paramyosin accumulates as a cytoplasmic protein in early
10 UNC-98 and anti-paramyosin colocalize in the paramyosin accumulations of missense alleles of unc-15 (
11 o paramyosin was confirmed using recombinant paramyosin and 125I-CaGC.
12  UNC-89's SH3 domain and residues 294-376 of paramyosin and has a KD of approximately 1.1 muM.
13                                              Paramyosins and tropomyosins were previously known mainl
14 (calreticulin, tropomyosin 1, tropomyosin 2, paramyosin, and triose phosphate isomerase) did not.
15 nstrated that Th2-biased immune responses to paramyosin are associated with resistance to reinfection
16 tokine responses, these data further support paramyosin as a leading vaccine candidate for human schi
17 in will facilitate preclinical evaluation of paramyosin as a vaccine for schistosomiasis.
18  a periodicity matching the 72-nm repeats of paramyosin, as revealed by immunoelectron microscopy.
19         Anti-CSN-5 antibody colocalized with paramyosin at A-bands in wild type and colocalized with
20 monstrating the antigenic specificity of the paramyosin-CaGG-binding complex.
21 ngent needles, which contain both UNC-98 and paramyosin, can be suppressed by starvation or by exposu
22                         Anti-UNC-98 and anti-paramyosin colocalize in the paramyosin accumulations of
23                    The SH3-binding region of paramyosin contains a "skip residue," which is likely to
24 phosphorylation sites near the N-terminus of paramyosin disabled.
25                        Coiled-coil dimers of paramyosin form a paracrystalline core of these filament
26 tudied the core proteins that, together with paramyosin, form the core structure of the thick filamen
27 d colocalized with abnormal accumulations of paramyosin found in unc-98, -96, and -15 (encodes paramy
28 e responses is confirmed by experiments with paramyosin from the tropical parasites Onchocerca volvul
29 onally disrupted the Drosophila melanogaster paramyosin gene by mobilizing a P element located in its
30 in the pilot-scale production of schistosome paramyosin have hampered further studies of this promisi
31 s mediating close contacts between MHC A and paramyosin in an antiparallel arrangement at the filamen
32 otein that coassembles with either myosin or paramyosin in C. elegans to form tubular filaments.
33  one isoform of myosin heavy chain (MHC) and paramyosin in Caenorhabditis elegans to probe the molecu
34 t discoveries include Rap v 2, an allergenic paramyosin in molluscs, and Sal s 4 and Pan h 4, allerge
35               To investigate the function of paramyosin in myofibril assembly and muscle contraction,
36 diates an avid interaction between MHC A and paramyosin in parallel arrangement in formation of the f
37 be the molecular interaction between MHC and paramyosin in vivo.
38 ere is no difference in the overall level of paramyosin in wild-type, unc-96, and -98 animals.
39 ilagenin assembled with the myosin homologue paramyosin into the tubular cores of wild-type nematodes
40 s chaperones to promote the incorporation of paramyosin into thick filaments.
41                           The phosphoprotein paramyosin is a major structural component of invertebra
42                                              Paramyosin is a major structural protein of thick filame
43                      In CB1214 mutants where paramyosin is absent, beta-filagenin assembled with myos
44                                              Paramyosin is an invertebrate-specific coiled-coil dimer
45 hat N-terminal phosphorylation of Drosophila paramyosin is essential for optimal force and oscillator
46 f-function mutants that lack the SH3 domain, paramyosin is found in accumulations.
47                                              Paramyosin is identified as a CaGC-binding protein in B.
48        When the SH3 domain is overexpressed, paramyosin is mislocalized.
49 red strains had decreases in the most acidic paramyosin isoforms, with a corresponding increase in mo
50                                              Paramyosin lacking the C-terminal UNC-96 binding region
51 paramyosin, UNC-98 is diminished, whereas in paramyosin missense mutants, UNC-98 is increased.
52 ramyosin-specific by rescuing the homozygous paramyosin mutant to adulthood with a paramyosin transge
53                                   Homozygous paramyosin mutants die at the late embryo stage.
54 ed by an embryonic version; the other group (paramyosin mutants) had one or more putative phosphoryla
55 nge-switch group, but a 15% reduction in the paramyosin mutants.
56 yosin found in unc-98, -96, and -15 (encodes paramyosin) mutants.
57 horylation sites in Drosophila suggests that paramyosin phosphorylation is important for maintaining
58  mechanical defects observed upon disrupting paramyosin phosphorylation sites in Drosophila suggests
59             To investigate the importance of paramyosin phosphorylation, we produced transgenic Droso
60                             We conclude that paramyosin plays an unexpected role in myoblast fusion a
61 ing purified proteins, UNC-98 interacts with paramyosin residues 31-693, whereas UNC-96 interacts wit
62 s UNC-96 interacts with a separate region of paramyosin, residues 699-798.
63 and purification of recombinant S. japonicum paramyosin (rSj97).
64             We demonstrate that, like native paramyosin, rSj97 adopts an alpha-helical coiled-coil te
65 ess in IFM myofibrils, probably by affecting paramyosin's interaction with other sarcomeric proteins.
66                All positive clones contained paramyosin sequences.
67          We confirmed that these defects are paramyosin-specific by rescuing the homozygous paramyosi
68                                         Anti-paramyosin stains the needles in unc-96 and -98 mutant m
69 e-rich consensus sequence, but the region of paramyosin that interacts with UNC-89's SH3 is alpha-hel
70 zygous paramyosin mutant to adulthood with a paramyosin transgene.
71             By immunoblot, in the absence of paramyosin, UNC-98 is diminished, whereas in paramyosin
72                  In vitro binding of CaGC to paramyosin was confirmed using recombinant paramyosin an
73                                              Paramyosin was thus considered the major CaGC-binding pr
74 hobic rod surface, making it more similar to paramyosin, which forms the thick filament core.
75 -scale production of recombinant full-length paramyosin will facilitate preclinical evaluation of par