ライフサイエンスコーパス: parathyroid adenoma

1 alization procedure and imaging protocol for parathyroid adenoma.

2 can technique in the preoperative imaging of parathyroid adenoma.

3 the successful preoperative localization of parathyroid adenomas.

4 to be technically feasible in patients with parathyroid adenomas.

5 1, a G1-S phase regulator, is upregulated in parathyroid adenomas.

6 ere uremic hyperparathyroidism versus common parathyroid adenomas.

7 ures of this disorder, compared with primary parathyroid adenomas.

8 splicing appears to occur preferentially in parathyroid adenomas.

9 tion-mediated inactivation of these genes in parathyroid adenomas.

10 strategy to identify oncogenes activated in parathyroid adenomas.

11 ccurate in the detection and localization of parathyroid adenomas.

12 lation of CCND1 regulatory genes in sporadic parathyroid adenomas.

13 t contribute commonly to the pathogenesis of parathyroid adenomas.

14 shown promise in presurgical localization of parathyroid adenomas.

15 ior imaging modality for the localization of parathyroid adenomas.

16 ivity of (18)F-FCH PET in detecting abnormal parathyroid adenomas.

17 line PET/CT for preoperative localization of parathyroid adenomas.

18 mary hyperparathyroidism is mainly caused by parathyroid adenomas.

19 e, 0.96-0.98), for the detection of abnormal parathyroid adenomas.

20 precisely identified 51 of 53 (96%) primary parathyroid adenomas, 14 to 15 secondary hyperplasias an

21 f the 168 patients, 120 (71.4%) had a single parathyroid adenoma, 15 (8.9%) had double adenoma, and 3

22 Surgery revealed 19 solitary parathyroid adenomas, 2 parathyroid adenomas in one pati

23 Of the 254 patients, 206 (81%) had a single parathyroid adenoma, 28 (11%) had double adenomas, 19 (8

24 loration in a series of patients with missed parathyroid adenomas after failed procedures for primary

25 ad positive intraoperative identification of parathyroid adenoma and MB staining (100% accuracy, 100%

26 Parathyroid adenomas and hyperplasia can be grouped into

27 Parathyroid adenomas and hyperplasias had similar Ki-67

28 dionuclide counts were highest in the single parathyroid adenomas and lowest in hyperplastic glands.

29 characterized by the development of multiple parathyroid adenomas and multiple fibro-osseous tumors o

30 Endocrine tumors, such as parathyroid adenomas and pheochromocytomas, frequently h

31 QPTH verified the excision of the primary parathyroid adenomas and predicted normocalcemia in 50 o

32 th localizing studies that indicate a single parathyroid adenoma are candidates for such approaches,

33 to insulin-producing islet cell tumors, and parathyroid adenomas are also frequently observed.

34 Parathyroid adenomas are benign tumors in the parathyroi

35 The most common ectopic sites for parathyroid adenomas are thymus (17%), intrathyroidal (1

36 Parathyroid adenomas are usually monoclonal, suggesting

37 rule" for ex vivo counts not only applies to parathyroid adenomas but also to hyperplastic glands.

38 Parafibromin was expressed in four parathyroid adenomas but was absent from two parathyroid

39 Localisation of small parathyroid adenomas by US-guided blue dye injection is

40 s and knowledge of the potential location or parathyroid adenomas can lead to very high cure rates wi

41 zation of parathyroid pathology, generally a parathyroid adenoma, can be difficult in some cases due

42 n is widely ordered preoperatively to locate parathyroid adenomas, concern about a false-positive sca

43 rticularly helpful in locating the 2 ectopic parathyroid adenomas diagnosed in this cohort.

44 Five lesions were interpreted incorrectly as parathyroid adenoma (false-positive), and all lesions ha

45 In 25 parathyroid adenomas, frequent loss of heterozygosity, i

46 tiate between healthy parathyroid tissue and parathyroid adenoma from 18 patients.

47 ectin-3 expression, consistent with atypical parathyroid adenomas, from 9 months of age.

48 in several sporadic or nonhereditary tumors-parathyroid adenomas, gastrinomas, insulinomas, and bron

49 Although preoperative localization of parathyroid adenomas has become sensitive enough for cli

50 All were parathyroid adenomas histologically.

51 vary in the involvement of pheochromocytoma, parathyroid adenoma/hyperplasia and developmental abnorm

52 gery was successful in 57 patients (solitary parathyroid adenoma in 48 patients, double parathyroid a

53 ure, CT correctly identified the side of the parathyroid adenoma in 54 of 62 patients (87%), while se

54 esults: [(18)F]flurpiridaz PET/CT identified parathyroid adenomas in 10 (91%) of the 11 patients stud

55 y parathyroid adenoma in 48 patients, double parathyroid adenomas in 6 patients, and 10 hyperplastic

56 t-PET/CT in the preoperative localization of parathyroid adenomas in a large series of patients with

57 ping permitted identification and removal of parathyroid adenomas in all patients with positive sesta

58 (18)F-fluorocholine PET for the detection of parathyroid adenomas in comparison to (99m)Tc-sestamibi

59 revealed 19 solitary parathyroid adenomas, 2 parathyroid adenomas in one patient; and 3 hyperplastic

60 bi-SPECT in the preoperative localization of parathyroid adenomas in patients with primary hyperparat

61 (18)F]flurpiridaz PET/CT for localization of parathyroid adenomas in patients with primary hyperparat

62 rioperative adjuncts can be used to localize parathyroid adenomas, including sestamibi-SPECT scanning

63 Understanding of the ectopic locations of parathyroid adenoma is of utmost importance in the condu

64 A single missed parathyroid adenoma is the most common cause for a faile

65 gle- or dual-phase planar or SPECT study for parathyroid adenoma localization.

66 addition of CT to SPECT may further improve parathyroid adenoma localization.

67 six patients with a positive PTH gradient, a parathyroid adenoma (mean weight 636 +/- 196 mg) was res

68 he diagnostic sensitivities for detection of parathyroid adenomas of 43% (9 of 21) for dual-phase ses

69 parathyroid tissue, allowing localization of parathyroid adenoma or hyperplasia in 96% of patients.

70 ive reports, with pathologic confirmation of parathyroid adenoma or hyperplasia.

71 of cases, the disease is caused by sporadic parathyroid adenoma or sporadic hyperplasia.

72 onventional SPECT in diagnosing and locating parathyroid adenomas or hyperplasia in patients with pri

73 14 in 94 patients with pathologically proven parathyroid adenomas or hyperplasia.

74 Parathyroid adenomas (PAs) causing primary hyperparathyr

75 g technique for preoperative localization of parathyroid adenomas (PTA) in patients with primary hype

76 al activity, and relative abundance of these parathyroid adenoma subpopulations likely reflect distin

77 Moreover, the parathyroid adenoma subtypes (chief cells and oxyphil ce

78 s had threefold more p27-positive cells than parathyroid adenomas, suggesting that p27 immunostaining

79 CT was used to localize a middle mediastinum parathyroid adenoma that was not detected with planar se

80 ules and recurring thyroid cancer as well as parathyroid adenomas that has yielded promising results

81 g technique for preoperative localization of parathyroid adenomas that involves multidetector CT imag

82 ng showed two related but different types of parathyroid adenomas that we have arbitrarily designated

83 prepared directly from a clinical sample of parathyroid adenoma tissue, transfected into NIH3T3 cell

84 (CDKN2A, CDKN2B and RASSF1A) was analysed in parathyroid adenoma tissues (n = 30).

85 diofrequency ablation of thyroid nodules and parathyroid adenomas to optimize the efficacy and safety

86 ntraoperative frozen section because excised parathyroid adenomas uniformly have radionuclide ex vivo

87 ty of MIBI scintigraphy for the detection of parathyroid adenomas warrants further investigation.

88 The sensitivity for parathyroid adenomas was 89%-98%, while the sensitivity

89 or genes are involved in the pathogenesis of parathyroid adenomas, we performed a more comprehensive

90 In the 37 patients who underwent surgery, parathyroid adenomas were confirmed in 34 (92%) and hype

91 Parathyroid adenomas were exclusively visualized in earl

92 Abnormal parathyroid adenomas were found in 209 of 222 initial pr

93 d not been previously described for sporadic parathyroid adenomas were noted with CGH, i.e., gains on

94 4 cm) and weight (mean = 1.50 +/- 2.56 g) of parathyroid adenoma, whereas patients with false-negativ

95 tudied 25 patients with surgically confirmed parathyroid adenomas with 99mTc-sestamibi parathyroid sc

96 ology and tumor size on the detectability of parathyroid adenomas with 99mTc-sestamibi scans.

97 or was supported by mutation screening in 48 parathyroid adenomas with cystic features, which identif

98 cellent tool in preoperative localization of parathyroid adenomas with sensitivity, specificity, and