ライフサイエンスコーパス: parathyroid hormone-related protein

1 sis in the absence of the receptor (PPR) for parathyroid hormone-related protein.

2 n turn leads to a reduction in the levels of parathyroid hormone-related protein.

3 ored epidermis expressed increased levels of parathyroid hormone-related protein.

4 and infiltrating macrophages also expressed parathyroid hormone-related protein.

5 Topical application of parathyroid hormone related protein (1-36) or parathyroi

6 parathyroid hormone-related protein agonist [parathyroid hormone-related protein (1-36)] and a parath

7 d the effects of topical administration of a parathyroid hormone-related protein agonist [parathyroid

8 It appears that parathyroid hormone-related protein and fibroblast growt

9 gated the spatial and temporal expression of parathyroid hormone-related protein and mRNA by immunohi

10 hyroid hormone-related protein (1-36)] and a parathyroid hormone-related protein antagonist [parathyr

11 mammary epithelial cells, r3T, which express parathyroid hormone-related protein but not receptor act

12 in the restoration of epidermal homeostasis, parathyroid hormone-related protein does not appear to b

13 ts and macrophages also represent sources of parathyroid hormone-related protein during the healing o

14 l line) confirmed that macrophages expressed parathyroid hormone-related protein, especially after ac

15 th progressive restoration of the pattern of parathyroid hormone-related protein expression in normal

16 growth factor [HGF], placental lactogen, or parathyroid hormone-related protein) have been targeted

17 Although the data suggest a role for parathyroid hormone-related protein in the healing of sk

18 To define better the role of parathyroid hormone-related protein in the skin, we inve

19 as been made in determining the roles of the parathyroid hormone-related protein, Indian hedgehog, fi

20 astatic cancer cells produce factors such as parathyroid hormone-related protein, interleukin-7, and

21 The humoral hypercalcemia factor parathyroid hormone-related protein is a paracrine-signa

22 gnal transduction by parathyroid hormone and parathyroid hormone-related protein is necessary and suf

23 Parathyroid hormone-related protein is produced by many

24 ss-breeding experiments employing keratin 14-parathyroid hormone-related protein mice and fibroblast

25 hair were 30-40% shorter in adult keratin 14-parathyroid hormone-related protein mice as compared wit

26 The dorsal skin of the keratin 14-parathyroid hormone-related protein mouse was used to ev

27 nditions demonstrated a 2.5-fold increase in parathyroid hormone-related protein mRNA expression acco

28 In the adult, parathyroid hormone-related protein mRNA expression was

29 PTHrP (parathyroid hormone-related protein) overexpression by p

30 n, increases Smad2/Smad3 phosphorylation and parathyroid hormone-related protein (PTH-rP) production

31 Conversely, treatment with parathyroid hormone related protein (PTHrP) increased ex

32 keratinocytes express, but do not respond to parathyroid hormone related protein (PTHrp), which incre

33 min D3, estrogen, parathyroid hormone (PTH), parathyroid hormone-related protein (PTHrP 1-34), and Ca

34 g endochondral bone and in developing teeth, parathyroid hormone-related protein (PTHrP) acts in chon

35 Parathyroid hormone-related protein (PTHrP) and hepatocy

36 n of Bone Morphogenetic Protein 4 (BMP4) and Parathyroid Hormone-related Protein (PTHrP) and inhibiti

37 ells are regulated by autocrine signaling by parathyroid hormone-related protein (PTHrP) and its para

38 Parathyroid hormone-related protein (PTHrP) and macropha

39 re it has been shown to inhibit secretion of parathyroid hormone-related protein (PTHrP) and particip

40 alpha also enhanced OCL formation induced by parathyroid hormone-related protein (PTHrP) and receptor

41 to localized disruption of the expression of parathyroid hormone-related protein (PTHrP) and the morp

42 Parathyroid hormone-related protein (PTHrP) and the PTH/

43 Prior reports have demonstrated that both parathyroid hormone-related protein (PTHrP) and the type

44 dentified hepatocyte growth factor (HGF) and parathyroid hormone-related protein (PTHrP) as two poten

45 eir cartilaginous moiety and the presence of parathyroid hormone-related protein (PTHrP) at their dis

46 e are regulated by the Indian hedgehog (IHH)-parathyroid hormone-related protein (PTHrP) axis.

47 yroid hormone (PTH) and its paracrine factor parathyroid hormone-related protein (PTHrP) both increas

48 mmonly caused by the increased production of parathyroid hormone-related protein (PTHrP) by a maligna

49 lignancy (HHM) is caused by the secretion of parathyroid hormone-related protein (PTHrP) by tumor cel

50 Parathyroid hormone-related protein (PTHrP) contributes

51 2, promotes chondrocyte hypertrophy, whereas parathyroid hormone-related protein (PTHrP) delays this

52 Parathyroid hormone-related protein (PTHrP) enhances rod

53 ng Colon-26 tumors develop increases in both parathyroid hormone-related protein (PTHrP) expression a

54 d hormone (PTH) and the functionally similar parathyroid hormone-related protein (PTHrP) have served

55 The role of parathyroid hormone-related protein (PTHrP) in fetal cal

56 dihydroxyvitamin D(3) (1,25-(OH)(2)D(3)) and parathyroid hormone-related protein (PTHrP) in mouse and

57 K14-PTHrP transgenic mice [which overexpress parathyroid hormone-related protein (PTHrP) in their dev

58 Parathyroid hormone-related protein (PTHrP) is a critica

59 Although parathyroid hormone-related protein (PTHrP) is a major m

60 Parathyroid hormone-related protein (PTHrP) is a major,

61 Parathyroid hormone-related protein (PTHrP) is a master

62 Previous studies have shown that parathyroid hormone-related protein (PTHrP) is a member

63 Parathyroid hormone-related protein (PTHrP) is a normal

64 Parathyroid hormone-related protein (PTHrP) is a prohorm

65 Parathyroid hormone-related protein (PTHrP) is essential

66 Parathyroid hormone-related protein (PTHrP) is expressed

67 Parathyroid hormone-related protein (PTHrP) is initially

68 Parathyroid hormone-related protein (PTHrP) is present i

69 Parathyroid hormone-related protein (PTHrP) is produced

70 Parathyroid hormone-related protein (PTHrP) is produced

71 Parathyroid hormone-related protein (PTHrP) is produced

72 Parathyroid hormone-related protein (PTHrP) is the agent

73 To determine whether the osteolytic factor parathyroid hormone-related protein (PTHrP) is the prima

74 Several studies have suggested that parathyroid hormone-related protein (PTHrP) might be sec

75 est that breast cancer cells in bone express parathyroid hormone-related protein (PTHrP) more frequen

76 Of particular interest was the lack of parathyroid hormone-related protein (PTHrP) mRNA express

77 The functions of parathyroid hormone-related protein (PTHrP) on morphogen

78 volves apoptosis and that, in the absence of parathyroid hormone-related protein (PTHrP) or its recep

79 Indian hedgehog (Ihh) and Parathyroid Hormone-related Protein (PTHrP) play a criti

80 Here we addressed the hypothesis that the parathyroid hormone-related protein (PTHrP) potentiates

81 In this report, we demonstrate that parathyroid hormone-related protein (PTHrP) production a

82 We have previously shown that the parathyroid hormone-related protein (PTHrP) promoter con

83 Parathyroid hormone-related protein (PTHrP) promotes ost

84 developing organs, parathyroid hormone (PTH)/parathyroid hormone-related protein (PTHrP) receptor (PP

85 expression of the Indian hedgehog (IHH) and parathyroid hormone-related protein (PTHrP) receptor gen

86 tors including extracellular nucleotides and parathyroid hormone-related protein (PTHrP) regulate ker

87 Parathyroid hormone-related protein (PTHrP) regulates ce

88 Parathyroid hormone-related protein (PTHrP) regulates pr

89 Parathyroid hormone-related protein (PTHrP) regulates th

90 Transgenic mice overexpressing parathyroid hormone-related protein (PTHrP) targeted to

91 h factor beta3 in the presence or absence of parathyroid hormone-related protein (PTHrP) to regulate

92 explant in serum-free culture, we have found parathyroid hormone-related protein (PTHrP) to regulate

93 Parathyroid hormone-related protein (PTHrP) treatment of

94 ) against the amino terminal region of human parathyroid hormone-related protein (PTHrP) was labeled

95 Parathyroid hormone-related protein (PTHrP) was original

96 Parathyroid hormone-related protein (PTHrP) was original

97 Parathyroid hormone-related protein (PTHrP), a normal pr

98 The bioactive conformation of parathyroid hormone-related protein (PTHrP), a single-ch

99 ceptor activator of NF-kappaB (RANK) ligand, parathyroid hormone-related protein (PTHrP), and macroph

100 Other proteins, including parathyroid hormone-related protein (PTHrP), are importe

101 t cancer cells increased tumor production of parathyroid hormone-related protein (PTHrP), enhanced os

102 h induces the expression of a second signal, parathyroid hormone-related protein (PTHrP), in the peri

103 Increased levels of parathyroid hormone-related protein (PTHrP), known to in

104 e receptor for parathyroid hormone (PTH) and parathyroid hormone-related protein (PTHrP), the PTH-1 r

105 nscription factor Gli2 as a key regulator of parathyroid hormone-related protein (PTHrP), which is pr

106 egulates endochondral ossification in both a parathyroid hormone-related protein (PTHrP)-dependent an

107 Parathyroid hormone-related protein (PTHrP)-expressing D

108 ed the ability of muRANK.Fc to inhibit human parathyroid hormone-related protein (PTHrP)-induced reso

109 s study, we show that neuroendocrine-derived parathyroid hormone-related protein (PTHrP)-mediated sig

110 tion of important osteolytic factors such as parathyroid hormone-related protein (PTHrP).

111 These events further activate parathyroid hormone-related protein (PTHrP).

112 ells were immunohistochemically positive for parathyroid hormone-related protein (PTHrP).

113 ivation, increased Indian hedgehog (Ihh) and parathyroid hormone-related protein (Pthrp, also known a

114 hway and that both Indian hedgehog (IHH) and parathyroid hormone-related protein (PTHrP, PTHLH) negat

115 Previous studies have shown that parathyroid hormone-related protein (PTHrP; also known a

116 Colony-stimulating factor-one (CSF-1) and parathyroid-hormone-related protein (PTHrP) down-regulat

117 cancer cachexia, we show that tumour-derived parathyroid-hormone-related protein (PTHrP) has an impor

118 or the quantification of a cancer biomarker (parathyroid hormone-related protein, PTHrP) in a real cl

119 +/Pi homeostasis via the parathyroid hormone/parathyroid hormone-related protein receptor (PTHR) in k

120 gen, fibroblast growth factor receptors 1-3, parathyroid hormone-related protein receptor, retinoic a

121 e mediated by the type I parathyroid hormone/parathyroid hormone-related protein receptor.

122 ng constitutively active parathyroid hormone/parathyroid hormone-related protein receptors (PPR*Tg).

123 ed that both colony-stimulating factor-1 and parathyroid hormone-related protein reduced OPG gene exp

124 Finally, the relationship between parathyroid hormone-related protein signaling and other

125 es such as hypercalcemia and in development, parathyroid hormone-related protein signaling appears to

126 sion data suggested that the Indian Hedgehog-parathyroid hormone-related protein signaling axis was i

127 ndrocytes and growth plate maturation by the parathyroid hormone-related protein signaling pathway.

128 In all samples, high levels of parathyroid hormone-related protein transcripts were exc

129 not only by parathyroid hormone, but also by parathyroid hormone-related protein, vasoactive intestin

130 Parathyroid hormone-related protein was expressed in nor