ライフサイエンスコーパス: parvovirus

1 e evolution and the biology of this emerging parvovirus.

2 s annotations within NCBI databases, such as parvovirus.

3 erminal domain, the first for any autonomous parvovirus.

4 irus B19 (B19V) is the only human pathogenic parvovirus.

5 n profile that was similar to that of bovine parvovirus.

6 extensive similarities with those of bovine parvovirus.

7 ons: canine distemper virus (CDV) and feline parvovirus.

8 in shaping exposure risk from CDV and feline parvovirus.

9 Muscovy duck- or other duck species-related parvoviruses.

10 wo dominant epitopes reported for autonomous parvoviruses.

11 stic dog TfR that dictates susceptibility to parvoviruses.

12 r how they differ from currently circulating parvoviruses.

13 ggests implications for replication of other parvoviruses.

14 ine tumor cell tropism for oncotropic rodent parvoviruses.

15 elded BLASTx E scores of 7e-05-0.008 against parvoviruses.

16 <31% identities to those of previously known parvoviruses.

17 maviruses, anelloviruses, herpesviruses, and parvoviruses.

18 oted after other infections, for example, by parvoviruses.

19 plant, and animal viruses, as well as other parvoviruses.

20 (GmDNV) but in stark contrast to vertebrate parvoviruses.

21 in many icosahedral viruses, including other parvoviruses.

22 n the fivefold channel as observed for other parvoviruses.

23 ng strategy of the B19 virus is unique among parvoviruses.

24 first noncoding RNA identified in autonomous parvoviruses.

25 ace topologies different from those of other parvoviruses.

26 d divergence of AAVR engagement within these parvoviruses.

27 vovirus (CPV), porcine parvovirus (PPV), rat parvovirus 1A (RPV1A), and H-3 were relatively ineffecti

28 ated virus, bovine influenza D virus, bovine parvovirus 2, bovine herpesvirus 6, bovine rhinitis A vi

29 Parvovirus 4 (PARV4) is a DNA virus frequently associate

30 d in human-derived samples: bocaviruses 1-4, parvovirus 4, bufavirus, tusavirus, and cutavirus.

31 on X-ray crystal structure of mature cricket parvovirus (Acheta domesticus densovirus [AdDNV]) has be

32 The parvovirus adeno-associated virus (AAV) contains a small

33 The life cycle of the human parvovirus adeno-associated virus (AAV) is orchestrated

34 The use of vectors based on the small parvovirus adeno-associated virus has gained significant

35 APOBEC3 proteins restrict herpesviruses and parvoviruses, among others, but whether they also work i

36 ly suggests that bidnaviruses evolved from a parvovirus ancestor from which they inherit a jelly-roll

37 on the basis of genomic similarity to bovine parvovirus and canine minute virus.

38 o human and animal parvoviruses (PVs) in the Parvovirus and Dependovirus genera within genomes of sev

39 isons at the strain (HBoV) and genus (bovine parvovirus and HBoV) levels identified differences in su

40 -1PV nucleotides to those observed in canine parvovirus and minute virus of mice, two members of the

41 Chimeras formed from combinations of canine parvovirus and portions of the parvovirus sequences from

42 EnPVs, one genetically more similar to genus Parvovirus and the other genetically more similar to the

43 ructure and biophysical properties to extant parvoviruses and also bound sialic acids and entered rod

44 d two genera in the family Parvoviridae, the parvoviruses and dependoviruses, were found and were bro

45 sm, pathogenicity, and antigenicity in other parvoviruses and likely play similar roles in these viru

46 ve been characterized that bind to different parvoviruses and mediate their entry into cells.

47 Here, we examine the properties of parvoviruses and their interactions with their hosts tha

48 herpes simplex virus, norovirus, rotavirus, parvovirus, and Epstein-Barr virus.

49 Enterovirus, kobuvirus, parechovirus, parvovirus, and rotavirus sequences were frequently dete

50 d perhaps of other A3s against retroviruses, parvoviruses, and hepatitis B virus.

51 ere used as a model system to detect porcine parvovirus antibody in swine sera via flow cytometry, an

52 acid sequence alone, the antigenic sites of parvoviruses appear to be dictated by structural feature

53 Members of the genus Parvovirus are small, nonenveloped single-stranded DNA v

54 Although parvoviruses are commonly described in domestic carnivor

55 Parvoviruses are commonly found in both vertebrate and i

56 vovirus epidemiology, suggesting that feline parvoviruses are endemic in wild carnivores in the Seren

57 om animals has shown just how widespread the parvoviruses are in nature, but most of the newly discov

58 new host species identified, and that canine parvoviruses are present in the dog population living ar

59 Parvoviruses are single-stranded DNA viruses that use th

60 Parvoviruses are small, rugged, nonenveloped protein par

61 Parvoviruses are structurally simple viruses with linear

62 g transmitted naturally.IMPORTANCE Carnivore parvoviruses are widespread among wild and domestic carn

63 Then, using porcine parvovirus as an example, we use these parameters to inv

64 surface loops from R. norvegicus with canine parvovirus assembled, allowing some of that capsid's str

65 nuclear replication compartments (autonomous parvovirus-associated replication [APAR] bodies) during

66 against human glioblastomas, we screened 12 parvoviruses at a high multiplicity of infection (MOI).

67 ive Finnish casualties from World War II for parvovirus B19 (B19V) DNA, and found a remarkable preval

68 Intrauterine parvovirus B19 (B19V) infection can be asymptomatic or m

69 lates viral DNA replication.IMPORTANCE Human parvovirus B19 (B19V) infection causes hematological dis

70 Human parvovirus B19 (B19V) infection has a unique tropism to

71 Parvovirus B19 (B19V) infection is highly restricted to

72 Human parvovirus B19 (B19V) infection is restricted to erythro

73 Accurate diagnosis of parvovirus B19 (B19V) infection requires the differentia

74 Human parvovirus B19 (B19V) infection shows a strong erythroid

75 Human parvovirus B19 (B19V) is a common pathogen in microvascu

76 Parvovirus B19 (B19V) is a member of the family Parvovir

77 Human parvovirus B19 (B19V) is a member of the genus Erythrovi

78 Parvovirus B19 (B19V) is pathogenic for humans and has a

79 Human parvovirus B19 (B19V) is the only human pathogenic parvo

80 Parvovirus B19 (B19V) nonstructural protein, NS1, a heli

81 ng of the precursor mRNA (pre-mRNA) of human parvovirus B19 (B19V) plays a key role in posttranscript

82 Alternative processing of parvovirus B19 (B19V) pre-mRNA is critical to generating

83 Lytic infection of human parvovirus B19 (B19V) takes place exclusively in human e

84 knowledge of the crystal structure of human parvovirus B19 (genus Erythrovirus).

85 ure red cell aplasia (PRCA) related to human parvovirus B19 (HPV-B19) infection.

86 cluding human papillomavirus 16 (HPV-16) and parvovirus B19 (PB-19), with a picomolar sensitivity.

87 Parvovirus B19 immunoglobulin M positivity was associate

88 irst-trimester serum samples were tested for parvovirus B19 immunoglobulin M positivity.

89 temporary genotypes of hepatitis B virus and parvovirus B19 in ancient human remains demonstrate that

90 gnostic assays, we discovered an outbreak of parvovirus B19 in dengue-suspected patients that occurre

91 Because parvovirus B19 infection during pregnancy has been assoc

92 In conclusion, acute parvovirus B19 infection during the first trimester of p

93 e neighboring VP2 capsid proteins.IMPORTANCE Parvovirus B19 is a common human pathogen and a particul

94 Parvovirus B19 is a long-known human pathogen, whereas a

95 Parvovirus B19 is a typical childhood infection, yet we

96 ly 0.1% of fetal losses were attributable to parvovirus B19 positivity, a proportion which could incr

97 wareness of co-circulating pathogens such as parvovirus B19 that may be hidden in plain sight.

98 ns (such as syphillis, varicella-zoster, and parvovirus B19), cytomegalovirus, and herpes simplex vir

99 1/2, human herpesvirus 8, hepatitis E virus, parvovirus B19).

100 ere detected in EMBs from 37 (39%) patients; parvovirus B19, adenovirus, and Epstein-Barr virus (EBV)

101 oinfection with HBV, and 1 case each of HBV, parvovirus B19, cytomegalovirus, and human herpesvirus 7

102 gene polymorphisms have been associated with parvovirus B19, hepatitis C virus, HIV-1/AIDS infection,

103 Parvovirus B19, one of the most common human pathogens,

104 Infections with human parvoviruses B19 and recently discovered human bocavirus

105 Parvovirus B19V infection can be a serious infection for

106 diversity between the different genera, most parvoviruses bind to negatively charged glycans, such as

107 Bovine parvovirus (BPV), identified in the 1960s in diarrheic c

108 Bovine parvovirus (BPV), the causative agent of respiratory and

109 of mice (MVM), a single-stranded DNA (ssDNA) parvovirus, but not hepatitis B virus.

110 The nonenveloped parvovirus capsid carries determinants of host and tissu

111 During cellular entry and infection, the parvovirus capsid follows a complex path from the cell s

112 tion 300 is the most variable residue in the parvovirus capsid in nature, suggesting that it is a cri

113 ere are common structural features among all parvovirus capsid proteins.

114 little structural resemblance to other known parvovirus capsid proteins.

115 Based on the comparison to other existing parvovirus capsid structures, this study suggests capsid

116 e examined the protein composition of canine parvovirus capsids and evaluated their structural variat

117 Parvovirus capsids are small but complex molecular machi

118 y, showed similarities to rodent and porcine parvovirus capsids.

119 ils that explain cell infection processes of parvovirus capsids.

120 Parvoviruses cause a variety of mild to severe symptoms

121 Mink enteritis virus (MEV), an autonomous parvovirus, causes acute hemorrhagic enteritis in minks.

122 Human bocavirus 1 (HBoV1), a human parvovirus, causes lower respiratory tract infections in

123 ts show GPgV lymphotropism and promote goose parvovirus clinical manifestations.

124 CPV, but not the related feline parvovirus, could use receptors containing a canine TfR-

125 Canine parvovirus (CPV) and feline panleukopenia virus (FPV) ar

126 The structures of canine parvovirus (CPV) and feline parvovirus (FPV) complexed w

127 Canine parvovirus (CPV) and its relative feline panleukopenia v

128 the emergence and pandemic spread of canine parvovirus (CPV) are well documented, the carnivore host

129 y visualize the association of single canine parvovirus (CPV) capsids with cellular transferrin recep

130 Canine parvovirus (CPV) emerged in the late 1970s as a host-ran

131 e capsid substitutions that eliminate canine parvovirus (CPV) infectivity and identify how those muta

132 Canine parvovirus (CPV) is a highly contagious pathogen that ca

133 Canine parvovirus (CPV) is a highly successful pathogen that ha

134 Canine parvovirus (CPV) is an important pathogen causing severe

135 Canine parvovirus (CPV) outbreaks can have a devastating effect

136 ti National Park (SNP) and, second, a canine parvovirus (CPV) route of transmission among domestic do

137 We studied the binding kinetics of canine parvovirus (CPV) variants isolated from raccoons-a newly

138 s important hosts in the evolution of canine parvovirus (CPV), a pandemic pathogen of domestic dogs.

139 , MVMc, MVM-G17, tumor virus X (TVX), canine parvovirus (CPV), porcine parvovirus (PPV), rat parvovir

140 e panleukopenia virus ("FPV-like") or canine parvovirus ("CPV-like").

141 e first study to report the highly conserved parvovirus DE loop at the 5-fold axis as a determinant o

142 However, unlike other parvoviruses, densities extending the 5-fold channel int

143 Parvovirus-derived endogenous viral elements (EVEs) have

144 FN-beta in glia; in contrast, LuIII and MVMp parvoviruses did not evoke a detectable IFN-beta or inte

145 We detected parvovirus DNA in several wildlife tissues.

146 ides the first evidence of the DDR-dependent parvovirus DNA replication that occurs in dividing cells

147 ggesting novel characteristics of autonomous parvovirus DNA replication.

148 Surprisingly, we found that these parvoviruses do not evoke an interferon response in norm

149 ntact was associated with exposure to canine parvovirus, Ehrlichia canis, Neospora caninum and perhap

150 Parvoviruses encode a large nonstructural protein 1 (NS1

151 ures and functions to be examined.IMPORTANCE Parvovirus endogenous viral elements (EVEs) that have be

152 ruses, as well as filovirus, bornavirus, and parvovirus endogenous viral elements.

153 r, phylogenetic analysis of these endogenous parvovirus (EnPV) sequences demonstrated substantial gen

154 The single-stranded DNA (ssDNA) parvoviruses enter host cells through receptor-mediated

155 tudy furthers the understanding of carnivore parvovirus epidemiology, suggesting that feline parvovir

156 To identify the parvovirus(es) with the optimal oncolytic effect against

157 her investigate the properties of autonomous parvovirus EVEs and describe their relationships to cont

158 expressing the capsid proteins of different parvovirus EVEs that were found integrated into the geno

159 irpins are highly conserved within the genus Parvovirus, exemplified by the 121-nucleotide left-end s

160 one using all known representative exogenous parvovirus (ExPV) and EnPV sequences showed two major ge

161 Sequences derived from parvoviruses (family Parvoviridae) are relatively common

162 ndogenous viral elements (EVEs) derived from parvoviruses (family Parvoviridae) in the genomes of the

163 The BPV capsid displays common parvovirus features: a channel at and depressions surrou

164 ctures of canine parvovirus (CPV) and feline parvovirus (FPV) complexed with antibody fragments from

165 es of transmission: first, an endemic feline parvovirus (FPV) route of transmission maintained by wil

166 aviruses with dsDNA genomes have evolved via parvoviruses from CRESS-DNA viruses.

167 s to follow the rocky road of emerging human parvoviruses from discovery of a DNA sequence to current

168 ison of the HBoV capsid structure to that of parvoviruses from five separate genera demonstrates stro

169 ofold-related neighbor similar to the insect parvovirus Galleria mellonella densovirus (GmDNV) but in

170 more clearly understand this unique mode of parvovirus gene expression.

171 ents further characterize the role of NP1 in parvovirus gene expression.IMPORTANCE The Parvovirinae a

172 ly triggered by integration of the ancestral parvovirus genome into a large virus-derived DNA transpo

173 ts characterization reveals another way that parvoviruses govern access to their capsid protein genes

174 arvovirus with a greater similarity to goose parvovirus (GPV) (97% protein homology) than to Muscovy

175 The goose parvovirus (GPV) Rep 1 and Rep 2 proteins are encoded by

176 losely clustered with two known goose-origin parvoviruses (GPVa2006 and GPV1995), together forming a

177 The parvoviruses H-1, LuIII, and MVM target cancer cells; ho

178 of single-stranded DNA (ssDNA) packaging H-1 parvovirus (H-1PV), which is being developed as an antit

179 Because the innate immune response to parvoviruses has received relatively little attention, w

180 Parvoviruses have a roughly cylindrically shaped pore th

181 Some human parvoviruses have already been shown to cause disease du

182 However, variants of some parvoviruses have altered their host ranges to create ne

183 Since 2005, many parvoviruses have been discovered in human-derived sampl

184 risons show that vertebrate and invertebrate parvoviruses have evolved independently, although there

185 Although parvoviruses have only subtle early-to-late expression s

186 MPORTANCE We first report that an autonomous parvovirus, HBoV1, helps the replication of a dependopar

187 Unlike infections with other parvoviruses, HBoV1 infection did not activate the apopt

188 tructural protein (Rep78/68 or NS1) of other parvoviruses, HBoV1 NS1 did not specifically bind OriR i

189 ted in the control of other viruses, such as parvoviruses, herpesviruses, papillomaviruses, hepatitis

190 Listeria monocytogenes, Treponema pallidium, parvovirus, HIV, varicella zoster virus, Rubella, Cytome

191 The parvovirus human bocavirus 1 (HBoV1) is an emerging resp

192 s, Salmonella spp., E. coli O157 and porcine parvovirus in bioreduction vessels containing sheep carc

193 inute virus of canine (MVC) is an autonomous parvovirus in the genus Bocaparvovirus It has a single p

194 nute virus of canines (MVC) is an autonomous parvovirus in the genus Bocaparvovirus.

195 cells plays a role in the oncoselectivity of parvoviruses in human cells.

196 first evidence for widespread circulation of parvoviruses in primates and enables future investigatio

197 The VP structure differs from those of other parvoviruses in surface loop regions that control recept

198 fecal samples were PCR positive for this new parvovirus, including a related bufavirus species showin

199 of these related genomes from those of other parvoviruses indicates the presence of a proposed new Pa

200 Parvoviruses infect a wide variety of hosts, and their a

201 Carnivore parvoviruses infect wild and domestic carnivores, and cr

202 us of the capsid viral protein VP1 (VP1u) in parvovirus infection has been reported.

203 The details of parvovirus infection of cells are still not fully unders

204 %, respectively, were positive for carnivore parvovirus infection, but little evidence of transmissio

205 uld promote clinical manifestations of goose parvovirus infection, including reduced weight gain and

206 been discovered about ATM activation during parvovirus infection, involvement of the ATR pathway has

207 ike most other types of virus, we found that parvovirus infectivity is unaffected by interferon treat

208 Little evidence of transmission of canine parvoviruses into wild carnivore species was found; howe

209 rst to support the notion that an autonomous parvovirus is able to hijack the host DNA damage machine

210 leads to the replication of the DNA of other parvoviruses is facilitated by the cell cycle, the DDR t

211 The diversity of parvoviruses is therefore extensive, and although they a

212 ocalize with PML, PML's functional effect on parvoviruses is unknown.

213 o-associated virus (AAV) serotype 9, a human parvovirus isolate.

214 The virus, provisionally named parvovirus-like hybrid virus (PHV), is nearly identical

215 V in human disease, our data indicate that a parvovirus-like virus is highly prevalent in a cohort of

216 ts and representatives of a clearly distinct parvovirus lineage that also has endogenous representati

217 The interferon-resistant phenotype of parvoviruses may give them an advantage over interferon-

218 s enhanced by oncogenic transformation, some parvoviruses may have potential utility in killing cance

219 (97% protein homology) than to Muscovy duck parvovirus (MDPV) (90% protein homology).

220 One initially human-labeled parvovirus might not even be a human virus, whereas anot

221 antigenic hotspots on AAVs and other related parvoviruses might be evolutionarily conserved.

222 MVM infection.IMPORTANCE Replication of the parvovirus minute virus of mice (MVM) induces a sustaine

223 The parvovirus minute virus of mice (MVM) packages a single

224 ex virus 1 and murine herpesvirus 68 and the parvovirus minute virus of mice (MVM).

225 s) during replication of the single-stranded parvovirus minute virus of mice (MVM).

226 a structural rearrangement that can occur in parvovirus minute virus of mice (MVMp) virions following

227 Human influenza viruses and Parvovirus Minute Viruses of Mice also specifically reco

228 Although dependovirus (AAV) and autonomous parvovirus (minute virus of mice) replication centers ca

229 Upon infection, the parvovirus MVM activates a cellular DNA damage response

230 estingly, we found that IFN did not decrease parvovirus (MVMp, LuIII, and H-1) infectivity in normal

231 Concurrent infections with either parvovirus (n = 1), attaching-effacing Escherichia coli

232 further verified by narrow peaks from murine parvovirus, norovirus, and encephalomyelitis virus sampl

233 and sequence the full VP2 gene of 150 canine parvoviruses obtained from a large cross-sectional sampl

234 Three new parvoviruses of Protoparvovirus genus, bufavirus (BuV),

235 In contrast with other parvoviruses, only expression of the MVC proteins by tra

236 astroviruses, rotaviruses, picobirnaviruses, parvoviruses, papillomaviruses, polyomaviruses, and a ga

237 Herpesviruses, parvoviruses, polyomaviruses, and bacteriophages were al

238 us X (TVX), canine parvovirus (CPV), porcine parvovirus (PPV), rat parvovirus 1A (RPV1A), and H-3 wer

239 NP1 is the first parvovirus protein implicated in RNA processing.

240 en fully elucidated, it represents the first parvovirus protein to be implicated directly in viral RN

241 We show here that MVC NP1, the first parvovirus protein to be implicated in RNA processing, g

242 Sequences from a highly divergent parvovirus, provisionally called bufavirus, were also de

243 In contrast to other parvoviruses, PstDNV probably has only one type of capsi

244 everal sequences related to human and animal parvoviruses (PVs) in the Parvovirus and Dependovirus ge

245 rrently, viruses of two distinct lineages of parvoviruses (PVs, family Parvoviridae; subfamily Hamapa

246 ing that GPV-QH15 evolved from goose lineage parvoviruses, rather than from Muscovy duck- or other du

247 investigate the exposure and circulation of parvoviruses related to B19 virus, PARV4, and HBoV in no

248 The mechanism of parvovirus replication has been studied mostly in the de

249 Because productive infection by parvoviruses requires cell division and is enhanced by o

250 circovirus and the capsid protein of porcine parvovirus, respectively.

251 nonstructural and capsid proteins of canine parvovirus, respectively.

252 2.1% with that of human bocavirus and bovine parvovirus, respectively.

253 -associated virus (AAV) is a single-stranded parvovirus retaining the unique capacity for site-specif

254 hese pipelines were implemented and detected parvovirus sequence in the sample that the ECBC iterativ

255 ons of canine parvovirus and portions of the parvovirus sequences from the brown rat genome allowed u

256 nute virus of mice, two members of the genus Parvovirus, showed both similarity in structure and anal

257 sed to identify a previously uncharacterized parvovirus species, "HBoV2," whose closest phylogenetic

258 s the first description of a vaccine-derived parvovirus strain being transmitted naturally.IMPORTANCE

259 d the alphaA helix, which are present in all parvovirus structures.

260 tropisms, have features in common with other parvoviruses, such as depressions at the icosahedral 2-f

261 , similar to findings for other invertebrate parvoviruses, suggesting domain swapping is an evolution

262 ation, which are processes necessary for all parvoviruses, suggests implications for replication of o

263 repare the nuclear environment for effective parvovirus takeover.

264 A new species of parvovirus, tentatively named human bocavirus 4 (HBoV4),

265 Human bocavirus 1 (HBoV1) is a human parvovirus that causes acute respiratory tract infection

266 bocavirus 1 (HBoV1) is a single-stranded DNA parvovirus that causes lower respiratory tract infection

267 H15 represents a new variant of goose-origin parvovirus that currently circulates in ducklings and ca

268 Human bocavirus 1 (HBoV1) is a parvovirus that gathers increasing attention due to its

269 sociated virus serotype 5 (AAV-5) is a human parvovirus that infects a high percentage of the populat

270 Human bocavirus 1 (HBoV1) is an autonomous parvovirus that infects well-differentiated primary huma

271 s is a newly identified, globally prevalent, parvovirus that is associated with respiratory infection

272 iated virus (AAV) is a replication-deficient parvovirus that is extensively used as a gene therapy ve

273 nute virus of canines (MVC) is an autonomous parvovirus that replicates efficiently without helper vi

274 anleukopenia virus (FPV) are closely related parvoviruses that differ in their host ranges for cats a

275 ssociated viruses (AAV) are helper-dependent parvoviruses that have been developed into promising gen

276 The full extent of the genetic diversity of parvoviruses that have undergone endogenization during e

277 ver recombinant genomes derived from another parvovirus, the adeno-associated virus (AAV).

278 Unlike other parvoviruses, the bocavirus genus controls expression of

279 In contrast to vertebrate parvoviruses, the N-terminal beta-strand of BmDNV-1 VP3

280 ocyte leukemia; infections, particularly B19 parvovirus; thymoma and other solid tumors; or a variety

281 ittle attention, we compared the response to parvoviruses to that of several other types of viruses i

282 Canine parvovirus type 2 (CPV-2) emerged as a variant of a feli

283 Canine parvovirus type 2 (CPV-2) emerged in 1978 and spread wor

284 Canine parvovirus type 2 (CPV-2) is a severe enteric pathogen o

285 Parvoviruses use a variety of means to control the expre

286 's effect on adeno-associated virus (AAV), a parvovirus used for gene delivery.

287 fection associated with enteritis as well as parvovirus viremia in animals with advanced AIDS, indica

288 Progeny production of parvoviruses was also unimpaired by IFN in both glioma a

289 The radiation of bidnaviruses from parvoviruses was probably triggered by integration of th

290 ive amino acid variation among the carnivore parvoviruses, we further investigated its role in determ

291 nversely, higher read numbers from different parvoviruses were associated with healthy animals.

292 Two human parvoviruses were recently discovered by metagenomics in

293 e 2 (CPV-2) emerged as a variant of a feline parvovirus when it acquired mutations that allowed bindi

294 de up 1 to 3% of the viral reads, except for parvoviruses, which made up 23% of the viral reads in th

295 HBoV1 is the first parvovirus whose NS1 has been shown to be able to activa

296 the tropism and pathogenicity of these novel parvoviruses will be facilitated by the availability of

297 and virological studies, which identified a parvovirus with a greater similarity to goose parvovirus

298 , including development of second-generation parvoviruses with enhanced oncolytic and immunostimulato

299 sm of LuIII's phenotype, we used recombinant parvoviruses with the LuIII capsid replacing the MVMp ca

300 most closely related to members of the genus Parvovirus, with >70% and 65% amino acid identities to n