ライフサイエンスコーパス: peripheral nerve

1 +/- 0.1 MPa, very similar to that of native peripheral nerve.

2 macrophage communication after damage to the peripheral nerve.

3 ctivity-dependent signaling mechanism in the peripheral nerve.

4 motor neurons by electrical stimulation of a peripheral nerve.

5 are essential for functional regeneration of peripheral nerve.

6 ominothoracic organs, skin, soft tissue, and peripheral nerves.

7 s inside the spinal cord following injury to peripheral nerves.

8 a signature resembling response to injury in peripheral nerves.

9 e local immune responses and diseases in the peripheral nerves.

10 ted in adaptive and maladaptive functions in peripheral nerves.

11 dulthood benign tumors involving cranial and peripheral nerves.

12 ted to the CNS via indirect sensitization of peripheral nerves.

13 ishes a latent reservoir in neurons of human peripheral nerves.

14 merged as the preferred modality for probing peripheral nerves.

15 ion of microvilli in the nodes of Ranvier of peripheral nerves.

16 lity of muscle fibres and the myelination of peripheral nerves.

17 ium retention in the brain, spinal cord, and peripheral nerves 24 hours after the last GBCA administr

18 of criticality were found in subcortical or peripheral nerve activity.

19 Diabetes triggers peripheral nerve alterations at a structural and functio

20 Therapies that target the highly accessible peripheral nerve and muscle system provide a promising n

21 nternal structure and pathophysiology of the peripheral nerves and diseases that involve them.

22 ibutes to promote axon regeneration in adult peripheral nerves and highlight that the sensory neuron

23 expression in vivo blocks myelination in the peripheral nerves and maintains Schwann cells in a proli

24 tially fatal, immune-mediated disease of the peripheral nerves and nerve roots that is usually trigge

25 anical, and chemical challenges posed by the peripheral nerves and organs.

26 motor capabilities, analogous approaches to peripheral nerves and peripheral myelin have fallen behi

27 ) are making it possible to assess different peripheral nerves and plexuses, including small sensory

28 nerves reverses functional alteration of the peripheral nerves and restores the homeostatic profiles

29 ids mainly found on brain neurons as well as peripheral nerves and skin melanocytes and are reported

30 ut the relationship between the stiffness of peripheral nerves and the severity of peripheral neuropa

31 Loss of myelin in the peripheral nerves and the spinal cord (SC) contributes t

32 xamine the evidence that ROS manipulation in peripheral nerves and/or muscle modifies mechanisms of p

33 ectromagnetic field simulations, an atlas of peripheral nerves, and a neurodynamic model to predict t

34 of the glia and extracellular matrix in the peripheral nerves, and reduction in larval locomotion.

35 polyneuropathy, which primarily affects the peripheral nerves, and transthyretin cardiomyopathy (TTR

36 Novel clinical treatments to target peripheral nerves are being developed which primarily us

37 r, these studies highlight the importance of peripheral nerves as a new therapeutic target for metabo

38 and reduced inflammation in lumbar roots and peripheral nerves at 10 months of age, along with enhanc

39 te mice present with early and age-dependent peripheral nerve axon defects.

40 ical signals for neural activity read-out in peripheral nerve axons.

41 inoids, and ketamine, and techniques such as peripheral nerve block and local infiltration analgesia

42 nase-2 inhibitors, gabapentinoids, ketamine, peripheral nerve blocks, and local infiltration analgesi

43 C-fiber compound action potential in distal peripheral nerves, but not proximal nerves or dorsal roo

44 for the first time, that the excitation of a peripheral nerve can be accomplished by 12-ns PEF withou

45 study, we found that injection of ATP into a peripheral nerve can mimic the effect of peripheral nerv

46 Peripheral nerves can modulate phenotype and behavior of

47 (LOS) that cross-react with gangliosides at peripheral nerves causing polyneuropathy.

48 of a spectrum of autoimmune diseases of the peripheral nerves, causing weakness and sensory symptoms

49 es as well as enhancing our understanding of peripheral nerve circuits.

50 Cells residing within peripheral nerves collaborate with cancer cells to enabl

51 ggests an anatomic etiology of pain, such as peripheral nerve compression, in select patients.

52 rt to an anatomic etiology of pain, that is, peripheral nerve compression, in select patients.

53 GM crops with the blood chemistry panel and peripheral nerve conduction of Chinese farmers.

54 Improvements in peripheral nerve conduction positively correlated with c

55 ith serial assessments of clinical features, peripheral nerve conduction, H and F components, thresho

56 Peripheral nerves contain axons and their enwrapping gli

57 tion.SIGNIFICANCE STATEMENT Although injured peripheral nerves contain repair Schwann cells that prov

58 Imaging compound action potentials (CAPs) in peripheral nerves could help avoid side effects in neuro

59 Hence, neuroinflammation in PD and peripheral nerve damage due to inflammation in T1R share

60 ermine what role this crystallin plays after peripheral nerve damage, we found that loss of alphaBC i

61 is reduced in sensory neurons in response to peripheral nerve damage.

62 Peripheral nerve degeneration or small fibre neuropathy

63 highlighting a novel role for these cells in peripheral nerve degeneration that spans genotypes.SIGNI

64 ignal through CCR2 to recruit macrophages to peripheral nerves, deletion of Ccr2 did not improve surv

65 ent herpes simplex virus (HSV) reactivation, peripheral nerve destruction and sensory anesthesia are

66 nuclear YAP/TAZ are essential regulators of peripheral nerve development and myelin maintenance.

67 nly one Ral GTPase was dispensable for early peripheral nerve development, ablation of both RalA and

68 Notch ligand Jagged1 (or JAG1) as a cause of peripheral nerve disease in 2 unrelated families with th

69 o identify the genetic cause for progressive peripheral nerve disease in a Venezuelan family.

70 severe vocal fold paresis, a rare feature of peripheral nerve disease that can be life-threatening.

71 sociated GBS, a potentially life-threatening peripheral nerve disease, remains unclear.

72 cot-Marie-Tooth disease type 2D (CMT2D) is a peripheral nerve disorder caused by dominant, toxic, gai

73 nd the mediators of leukocyte trafficking in peripheral nerves during normal immunosurveillance.

74 ed associative stimulation (a combination of peripheral nerve electrical stimulation and transcranial

75 els and by morphological differences between peripheral nerve endings of small and large fibers.

76 anglia (DRG), the morphology and location of peripheral nerve endings of spinal afferents that transd

77 ast cells can be found in close proximity to peripheral nerve endings where, upon activation, they re

78 y tight junction-forming microvessels within peripheral nerve endoneurium, exists to regulate its int

79 SP released from the peripheral nerves exerts its biological and immunologica

80 europathy affecting only the spinal cord and peripheral nerves (Expanded Disability Status Scale scor

81 round adventitial nerve bundles and form the peripheral nerve-extrafascicular tissue barrier (perineu

82 ATION: The recovered function of regenerated peripheral nerve fibers and reinnervated mechanoreceptor

83 l model was developed to study activation of peripheral nerve fibers by different cutaneous electrode

84 tes from the skin and is transferred through peripheral nerve fibers to the central nervous system.

85 axonal membrane of nociceptive, unmyelinated peripheral nerve fibers, but clarifying the role of sodi

86 orsal root ganglia (DRG) to the axon and any peripheral nerve fibre type.

87 bMed was searched for articles investigating peripheral nerve fluorescence.

88 Artificial electrical stimulation of peripheral nerves for sensory feedback restoration can g

89 uding the cerebral leptomeninges, brainstem, peripheral nerves from both fore and hind limbs, stifle

90 tail tip to the origin of the most posterior peripheral nerves from the dorsal nerve cord.

91 e Schwann cells (SCs) play a central role in peripheral nerve function and can be the target for dama

92 s and presents as distal-to-proximal loss of peripheral nerve function in the lower extremities.

93 Impairment of peripheral nerve function is frequent in neurometabolic

94 for both the development and maintenance of peripheral nerve function.

95 in sensory neurons are necessary for proper peripheral nerve function.

96 virus 1 (HSV-1) establishes latency in both peripheral nerve ganglia and the central nervous system

97 ) establishes a lifelong latent infection in peripheral nerve ganglia.

98 ost contusive spinal cord injury, we built a peripheral nerve graft bridge (PNG) through the cystic c

99 Similar to peripheral nerves, GSK3-mediated MAP1B phosphorylation/a

100 pecific macrophages dedicated to homeostatic peripheral nerves have come into focus.

101 Imaging studies of peripheral nerves have increased considerably in the las

102 transporters with relevance to understanding peripheral nerve homeostasis and pharmacology, including

103 clinical applications of conduction block of peripheral nerve hyperactivity, for example in pain and

104 nt attention, recent studies have identified peripheral nerve hyperexcitability as a driver of persis

105 Peripheral nerve imaging might assist this differential

106 ary of the current knowledge of COVID-19 and peripheral nerve imaging.

107 also has the potential to invade the CNS via peripheral nerves in a prion-like manner.

108 molecular mechanisms of paranodal damage at peripheral nerves in both the immune-mediated and the ge

109 n this review, we summarize the functions of peripheral nerves in glucose regulation and metabolism.

110 onships between the systemic circulation and peripheral nerves in health, adaptations to intrinsic or

111 studied the role of Golgi in myelination of peripheral nerves in mice through SC-specific genetic in

112 topically exit the spinal cord and myelinate peripheral nerves in myelin with CNS characteristics.

113 Imaging of peripheral nerves in patients with COVID-19 may help to

114 wave elastography (SWE) in the evaluation of peripheral nerves in patients with neuropathy of various

115 dolinium was retained in the spinal cord and peripheral nerves in rats exposed to multiple administra

116 nanoclip - for chronic interfacing with fine peripheral nerves in small animal models that begins to

117 illustrate an unexpected and novel role for peripheral nerves in the creation of acini throughout de

118 ment-improved electronic conductivity of the peripheral nerves increased mobility and restored mitoch

119 I3Kdelta in Treg cells developed spontaneous peripheral nerve inflammation.

120 Peripheral nerve injuries can be extremely debilitating,

121 Neuropathic pain caused by peripheral nerve injuries significantly affects sensory

122 tion as distal stimulators in a rat model of peripheral nerve injuries, thereby demonstrating the pot

123 eat neurological diseases such as stroke and peripheral nerve injuries.

124 y processing in excitatory neurons following peripheral nerve injuries.

125 d molecular therapies to improve outcomes of peripheral nerve injuries.

126 animals with spared nerve injury, a model of peripheral nerve injury (PNI)-induced neuropathic pain.

127 Peripheral nerve injury accounts for roughly 2.8% of all

128 wann cells readily dedifferentiate following peripheral nerve injury and become repair cells.

129 dynamics in the dorsal horn associated with peripheral nerve injury and pain.

130 A detailed background of peripheral nerve injury and repair pathology, and an in-

131 nation during both development and following peripheral nerve injury and repair.

132 o a peripheral nerve can mimic the effect of peripheral nerve injury and significantly increase the n

133 Peripheral nerve injury can occur in patients with COVID

134 nization of essential motor circuits after a peripheral nerve injury can result in permanent motor de

135 at transcription factors induced early after peripheral nerve injury confer the cellular plasticity r

136 lia (DRG), the primary sensory cell body for peripheral nerve injury generated hypersensitivity, and

137 then discuss the pathways that contribute to peripheral nerve injury in DN.

138 scular junctions and hastened recovery after peripheral nerve injury in wild type mice.

139 Here, we report that peripheral nerve injury increases expression of the DNA

140 Mechanistically, peripheral nerve injury induces DNA demethylation and up

141 Interestingly, peripheral nerve injury induces tactile allodynia and up

142 he activation of dorsal horn microglia after peripheral nerve injury is a significant expansion and p

143 o find that cold hypersensitivity induced by peripheral nerve injury is reduced in eIF4E(S209A) and M

144 These RNA-Seq data analyses indicate that peripheral nerve injury may result in highly selective m

145 s mechanical and thermal hypersensitivity in peripheral nerve injury models of neuropathic pain.

146 eus accumbens (NAc) neurons in mouse and rat peripheral nerve injury models of neuropathic pain.

147 While a regeneration-competent peripheral nerve injury mounts a regenerative gene expre

148 Peripheral nerve injury results in persistent motor defi

149 ndergo a similar transcriptional response to peripheral nerve injury that both promotes axonal regene

150 Peripheral nerve injury upregulated DNMT1 expression in

151 Following peripheral nerve injury, innocuous stimuli activated thi

152 There is consensus that, distal to peripheral nerve injury, myelin and Remak cells reorgani

153 during development of SC lineage and during peripheral nerve injury, so we sought to study their fun

154 adult dorsal root ganglion neurons following peripheral nerve injury, triggering selective degenerati

155 al horn (lamina II) neurons before and after peripheral nerve injury-induced pain.

156 echanical and thermal hypersensitivity after peripheral nerve injury.

157 ription factor CREB in the injured DRG after peripheral nerve injury.

158 aling and sensitization of nociceptors after peripheral nerve injury.

159 neuropathic and inflammatory pain following peripheral nerve injury.

160 i silkworms can support axon regeneration in peripheral nerve injury.

161 Sensation is essential for recovery after peripheral nerve injury.

162 al and behavioral alterations resulting from peripheral nerve injury.

163 get muscle is a determinant of outcome after peripheral nerve injury.

164 mechanism for activation of autophagy after peripheral nerve injury.

165 to manage chronic neuropathic pain following peripheral nerve injury.

166 al root ganglion neurons using two models of peripheral nerve injury: chronic constriction injury (CC

167 niscent of IRF8-driven reactive microglia in peripheral-nerve injury.

168 ight a critical role for JAG1 in maintaining peripheral nerve integrity, particularly in the recurren

169 ake meaningful comparisons between different peripheral nerve interfaces.

170 de a strategy to better define axon types in peripheral nerve interfaces.

171 LV2-14 patients were more likely to have peripheral nerve involvement, an intact circulating immu

172 al differences in mitochondrial responses of peripheral nerve, kidney, and retinal tissues to T2D in

173 INTERPRETATION: Peripheral nerve lesions could be visualized and quantif

174 To detect and quantify peripheral nerve lesions in multiple sclerosis (MS) by m

175 from their cell body, but partial injury to peripheral nerves may leave the integrity of damaged axo

176 Injury of peripheral nerves may quickly induce severe pain, but th

177 In the peripheral nerve, mechanosensitive axons are insulated b

178 nical studies have suggested that changes in peripheral nerve microcirculation may contribute to nerv

179 r interacting networks provide insights into peripheral nerve microvascular morphogenesis, restrictiv

180 we hypothesize that injection of ATP into a peripheral nerve might mimic the stimulatory effect of n

181 ith shortened lifespan in rodents and severe peripheral nerve myelin abnormalities in several species

182 Copy number variation of the peripheral nerve myelin gene Peripheral Myelin Protein 2

183 ions in the formation and maintenance of the peripheral nerve myelin sheath.

184 MPZ/P0) is the most abundant glycoprotein of peripheral nerve myelin.

185 onal neuregulin 1 type III (Nrg1TIII) drives peripheral nerve myelination by activating downstream si

186 and secreted by Schwann cells that regulates peripheral nerve myelination via its cognate receptor AD

187 Hippocampal axonal guidance and peripheral nerve myelination were not affected.

188 ave shown that NECL4 is necessary for proper peripheral nerve myelination.

189 nd the sets of reference values for specific peripheral nerves need to be determined.

190 rtefacts, such as bones, on the stiffness of peripheral nerves needs to be verified.

191 ne treated rhesus macaque, and adjacent to a peripheral nerve of an untreated animal.

192 In conclusion, DTI-MRN enables detection in peripheral nerves of abnormalities related to DPN, more

193 In the dorsal roots and proximal peripheral nerves of mice and nonhuman primates, TTX red

194 observed in heart, skeletal muscle, and near peripheral nerves of treated and untreated animals.

195 Peripheral nerves pass from the dermis to the epidermis

196 have led to the identification of structural peripheral nerve pathologies in NA, most notably hourgla

197 bsence of brain alters subsequent muscle and peripheral nerve patterning during early development.

198 brain early in development alters muscle and peripheral nerve patterning, which can be rescued by mod

199 As peripheral nerves ramify within the dermis, all the nucl

200 In peripheral nerves, recording movement intent is challeng

201 K3(S/A) knock-in mice reportedly accelerates peripheral nerve regeneration via increased MAP1B phosph

202 as a comprehensive, in-depth perspective on peripheral nerve regeneration, particularly nerve guidan

203 nse may be a major constraint on the rate of peripheral nerve regeneration.

204 rived cells at two differentiation stages on peripheral nerve regeneration.

205 sor helps reprogram Schwann cells to promote peripheral nerve regeneration.

206 ent.SIGNIFICANCE STATEMENT Repair of injured peripheral nerves remains a critical clinical problem.

207 control of Schwann cell (SC) plasticity and peripheral nerve repair after injury.

208 ngineering an alternative "nerve bridge" for peripheral nerve repair remains elusive; hence, there is

209 Schwann cells, the key regulators of peripheral nerve repair, have recently been shown to dir

210 alternative paradigm to stimulate endogenous peripheral nerve repair.

211 The myelination of axons in peripheral nerves requires precisely coordinated prolife

212 ings and videography to identify central and peripheral nerves responsible for nociception and sensit

213 al depigmentation and absence of myelin from peripheral nerves, resulting from alterations in melanoc

214 e diabetes-induced ROS production in SCs and peripheral nerves reverses functional alteration of the

215 n potentials (C-CAPs) of proximal and distal peripheral nerve segments and dorsal roots from mice and

216 Thus, peripheral nerves serve as a stem cell niche for neuroen

217 g of the highly specialised nodal regions of peripheral nerves serves to strengthen the links between

218 expression in the TME of cutaneous malignant peripheral nerve sheath tumor (C-MPNST) and spindle cell

219 Malignant peripheral nerve sheath tumor (MPNST) is an aggressive s

220 Malignant peripheral nerve sheath tumor (MPNST) is an aggressive s

221 coma (LMS), synovial sarcoma (SS), malignant peripheral nerve sheath tumor (MPNST), and undifferentia

222 PN can undergo transformation to a malignant peripheral nerve sheath tumor, an aggressive soft-tissue

223 ed imaging characteristics of lipoma, benign peripheral nerve sheath tumor, and vascular malformation

224 gues explore epigenetic drivers of malignant peripheral nerve sheath tumors (MPNST) harboring loss-of

225 d role has not been established in malignant peripheral nerve sheath tumors (MPNST) where NF1 mutatio

226 , Ewing sarcomas, leiomyosarcomas, malignant peripheral nerve sheath tumors (MPNST), solitary fibrous

227 ity and is altered in about 90% of malignant peripheral nerve sheath tumors (MPNST).

228 be precursor lesions of aggressive malignant peripheral nerve sheath tumors (MPNST).

229 fector pathways in the majority of malignant peripheral nerve sheath tumors (MPNST).

230 Malignant peripheral nerve sheath tumors (MPNSTs) are a type of ra

231 Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive n

232 Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive,

233 Malignant peripheral nerve sheath tumors (MPNSTs) are devastating

234 Malignant peripheral nerve sheath tumors (MPNSTs) are soft-tissue

235 In malignant peripheral nerve sheath tumors (MPNSTs), Polycomb repres

236 this approach is being applied to malignant peripheral nerve sheath tumors (MPNSTs), rare Schwann ce

237 as a central oncogenic driver for malignant peripheral nerve sheath tumors (MPNSTs), which are highl

238 logic potential (ANNUBP) and/or to malignant peripheral nerve sheath tumors (MPNSTs).

239 In malignant peripheral nerve sheath tumors and CNS tumors, the cance

240 c sarcomas, myxofibrosarcomas, and malignant peripheral nerve sheath tumors are characterized by comp

241 N/S HNSTs cluster in a distinct subgroup of peripheral nerve sheath tumors based on genome-wide DNA

242 Malignant peripheral nerve sheath tumors often arise in patients w

243 Intraneural perineuriomas are benign peripheral nerve sheath tumors that cause progressive de

244 ignant gliomas, neurofibromas, and malignant peripheral nerve sheath tumors, as well as behavioral, c

245 and RalB act downstream of Ras in malignant peripheral nerve sheath tumors.

246 -fixed, paraffin-embedded specimens of human peripheral nerve sheath tumors.

247 s trial was deemed inappropriate), malignant peripheral nerve sheath tumour, non-metastatic and gross

248 tumour of bone to chondrosarcoma, malignant peripheral nerve sheath tumour, synovial sarcoma, epithe

249 Compound muscle action potentials in peripheral nerves showed peripheral neuropathy associate

250 ld apply to other techniques for controlling peripheral nerve signaling.

251 Finally, we introduce a preparation of peripheral nerve slices for patch-clamp recordings.

252 We established a novel preparation of living peripheral nerve slices with preserved cellular architec

253 theless, the sources of heterogeneity in the peripheral nerve stiffness in healthy persons need to be

254 ll these issues, elastographic evaluation of peripheral nerve stiffness might become a reliable, easi

255 ces electric fields powerful enough to cause Peripheral Nerve Stimulation (PNS).

256 Multiple studies have demonstrated that peripheral nerve stimulation and targeted reinnervation

257 ng-term manner if afferent volleys evoked by peripheral nerve stimulation are repeatedly associated w

258 spinal excitability of repeatedly delivering peripheral nerve stimulation at three time points (-30 m

259 5) We suggest that peripheral nerve stimulation with train-of-four monitori

260 olving transcranial magnetic stimulation and peripheral nerve stimulation.

261 specific group, and the reference values for peripheral nerve strain in sportspersons need to be dete

262 eptors in other tissues, including brain and peripheral nerves, suggests a potential wider biological

263 s in such cases, indicating the viability of peripheral nerve surgery as a valuable treatment option

264 Recent studies have shown that peripheral nerves (sympathetic, parasympathetic and sens

265 abolism and calcium handling in cells of the peripheral nerve system (PNS).

266 17c is a neurotrophic cytokine that protects peripheral nerve systems during HSV reactivation.

267 ub-populations of sensory neurons, and their peripheral nerve terminal endings, interact with bone.

268 Immune cells at peripheral nerve terminals and within the spinal cord re

269 in the whole body and found degeneration of peripheral nerve terminals in the torso.

270 veal a remarkable self-healing capability of peripheral nerves that are affected by SC loss.

271 ation.SIGNIFICANCE STATEMENT After injury to peripheral nerves, the myelin and Remak Schwann cells di

272 t target muscle, the neuromuscular junction, peripheral nerves, the spinal cord or the brain and disc

273 Sensory information is transmitted from peripheral nerves, through the spinal cord, and up to th

274 Sensory information is transmitted from peripheral nerves, through the spinal cord, and up to th

275 n which patients develop benign tumors along peripheral nerves throughout the body.

276 nt an in vitro biomimetic model of all-human peripheral nerve tissue capable of showing robust neurit

277 organization of the extracellular matrix in peripheral nerve tissue in MS.

278 features of highly purified cells from human peripheral nerve tissues.

279 ike cell underlies the remarkable ability of peripheral nerves to regenerate following injury.

280 l-tRNA synthetase (GlyRS), mediate selective peripheral nerve toxicity resulting in Charcot-Marie-Too

281 Peripheral nerve transection is associated with permanen

282 aximise functional outcomes following severe peripheral nerve trauma.

283 his end, we built a computational model of a peripheral nerve trunk in which the interstitial space b

284 Plexiform neurofibroma, a benign peripheral nerve tumor, is associated with the biallelic

285 Neurofibromas are benign peripheral nerve tumors driven by NF1 loss in Schwann ce

286 When NMES is delivered to a mixed peripheral nerve, typically both efferent and afferent f

287 ed B cell type, with posterior resolution of peripheral nerves uptake after beginning chemotherapy.

288 ng ocular neovascularization and suppressing peripheral nerve virus replication in the near absence o

289 clude: "intraoperative, nerve, fluorescence, peripheral nerve, visualization, near infrared, and myel

290 significant variants and gene expression in peripheral nerves was evaluated in the Genotype-Tissue E

291 shows reduced inactivation, suggesting that peripheral nerves were more sensitive to painful stimuli

292 icrophysiological system of myelinated human peripheral nerve which can be used for evaluating electr

293 t frequently using electrical stimulation of peripheral nerves, which is not a physiological or selec

294 ama1 was upregulated in skeletal muscles and peripheral nerves, which prevented muscle fibrosis and p

295 e in Nox4 expression and activity in SCs and peripheral nerves, which were further verified in skin b

296 ly, infrared (IR) light was shown to inhibit peripheral nerves with high spatial and temporal specifi

297 The interaction of peripheral nerves with myeloid cells has largely been in

298 DPN presents deterioration of peripheral nerves with pain, feebleness, and loss of sen

299 hy techniques available for the study of the peripheral nerves, with special emphasis on new sequence

300 Better understanding myelination of peripheral nerves would benefit patients affected by per