ライフサイエンスコーパス: periplasm

1 (FBPase) are in the extracellular fraction (periplasm).

2 lower (37 +/- 3 vs 221 +/- 10 pg/muL for the periplasm).

3 rface where the domains meet facing into the periplasm.

4 e and transfers the product, nitrite, to the periplasm.

5 at stall early in the folding process in the periplasm.

6 y coupling motif termed the Ton box into the periplasm.

7 r associated lipoproteins, BamB-BamE, in the periplasm.

8 gene by sensing Mg(2+) concentrations in the periplasm.

9 nked substrates to proteins in the bacterial periplasm.

10 CueP, a major copper-binding protein in the periplasm.

11 ophobic tunnel sufficiently long to span the periplasm.

12 eral secretion-mediated translocation to the periplasm.

13 ved to be exclusively located in T. pallidum periplasm.

14 n the transmembrane pore as FeEnt enters the periplasm.

15 tive environment of the POTRA domains in the periplasm.

16 ope by anchoring the beta-barrels within the periplasm.

17 donuclease activity that is localized to the periplasm.

18 ns for the transport of small solutes to the periplasm.

19 ectively import various C27 sterols into the periplasm.

20 s to modulate pilus assembly from within the periplasm.

21 ked an AT passenger remained unfolded in the periplasm.

22 MOSP(N)-like domains are tethered within the periplasm.

23 tant to a process understood to occur in the periplasm.

24 and a large C-terminal region exposed to the periplasm.

25 domain remains unfolded until it reaches the periplasm.

26 alysis of oxidative folding in the bacterial periplasm.

27 domains of the FtsB and FtsL proteins in the periplasm.

28 studies suggested that BB0744 resides in the periplasm.

29 f pre-folded, fully active endolysins to the periplasm.

30 ure of MalK2 and opening of MalFG toward the periplasm.

31 nown for disulfide bond isomerization in the periplasm.

32 hoQ is activated by different signals in the periplasm.

33 is connected to a cage-like vestibule in the periplasm.

34 ulfide bond catalyst DsbA, LacZ folds in the periplasm.

35 thiols from the oxidizing environment of the periplasm.

36 e and the C-terminal signaling domain in the periplasm.

37 erophore enterobactin, which collects in the periplasm.

38 YfiR disulfide bonds stabilized YfiR in the periplasm.

39 (-1), respectively, and was localized in the periplasm.

40 metal ion transfer from CusF to CusA in the periplasm.

41 eously occurring OMP folding reaction in the periplasm.

42 -length protein remained inactive in E. coli periplasm.

43 abolic enzyme in that it is localized in the periplasm.

44 e, through the channel of MlaD, and into the periplasm.

45 ing intact the inner and outer membranes and periplasm.

46 the cytoplasmic membrane into the bacterial periplasm.

47 ulating FMN and FAD levels in the treponemal periplasm.

48 y for the translocation of lipids across the periplasm.

49 ibly acts by oxidation of toxic Cu(I) in the periplasm.

50 ine binding protein (LBP) from the bacterial periplasm.

51 rojection of the N-terminal domains into the periplasm.

52 with a pseudopilus structure that spans the periplasm.

53 carbon dioxide, which buffer the pathogen's periplasm.

54 predominant orientation facing in toward the periplasm.

55 a role in sensing or oxidizing metals in the periplasm.

56 nB displaces the N-terminus further into the periplasm.

57 in folding soluble proteins in the bacterial periplasm.

58 ng as the prerequisite to gain access to the periplasm.

59 box and blocks access of the Ton box to the periplasm.

60 unctional due to misfolding in the bacterial periplasm.

61 proteins on disulphide bond formation in the periplasm.

62 xoS sensor through direct interaction in the periplasm.

63 leading to Mn(2+) preloading of PSII in the periplasm.

64 s or released as free oligosaccharide in the periplasm.

65 CPAF is available for processing OmcB in the periplasm.

66 and Rz1 form complexes that span the entire periplasm.

67 the few residues of ExbB known to occupy the periplasm.

68 iate the formation of disulfide bonds in the periplasm.

69 s for active transport of nutrients into the periplasm.

70 subset of F-plasmid-encoded proteins in the periplasm.

71 oglycan biosynthetic apparatus active in the periplasm.

72 iated proteins targeted for secretion to the periplasm.

73 AcrA contacts the peptidoglycan layer of the periplasm.

74 in polymerization and filament growth in the periplasm.

75 hannel with openings toward the membrane and periplasm.

76 chinery exports phospholipids to MlaC in the periplasm.

77 r channel across the outer membrane into the periplasm.

78 ce (PMF) is not required to keep P(i) in the periplasm.

79 events accumulation of toxic products in the periplasm.

80 eria of numerous proteins that reside in the periplasm.

81 cterized proteins predicted to reside in the periplasm.

82 uld be coupled to substrate secretion to the periplasm.

83 tein required for the import of DNA into the periplasm.

84 membrane and Lpt protein interactions in the periplasm.

85 and Ag(I) to the CusCBA transporter from the periplasm.

86 very of its own TonB1-binding epitope to the periplasm.

87 coil-coiled platform spanning the bacterial periplasm.

88 rophore moiety to facilitate uptake into the periplasm.

89 urface-exposed, while MOSP(N) resides in the periplasm.

90 y electronegative surface of PelC toward the periplasm.

91 irmed that the protein is transported to the periplasm.

92 e outer leaflet of the inner membrane to the periplasm.

93 physiological importance of the size of the periplasm.

94 mation about flavin utilization in bacterial periplasms.

95 As the polymer passages through the periplasm, 22-44% of the mannuronate residues are conver

96 und was located in the cytoplasm than in the periplasm (592 +/- 50 pg vs 277 +/- 13 pg per 3.9 x 10(9

97 The OM and the IM are separated by the periplasm, a compartment that contains the peptidoglycan

98 (patA) for translocation of acetate into the periplasm, a PG O-acetyltransferase B (patB) for O-acety

99 contrast, the accumulation of P(i) into the periplasm across the OM is PMF-dependent and can be enha

100 ansport protein D) translocates LPS from the periplasm across the outer membrane (OM).

101 aminopeptidase, PepN, expression of PepN in periplasm allowed us to carry out a quantitative determi

102 ex, where its role is to reorient DPA to the periplasm, allowing this arabinose donor to then be used

103 le compounds are conveyed across the aqueous periplasm along specific molecular transport routes: the

104 in reducing pathways in the Escherichia coli periplasm, also possess denitrosylating activity.

105 l-asparaginase II localizes primarily to the periplasm and acts together with l-asparaginase I to pro

106 rotein, and similar to BB0323, exists in the periplasm and as a membrane-bound protein.

107 ut how precursors of such proteins cross the periplasm and assemble into the OM.

108 in is localized in the thylakoids and in the periplasm and can be functionally replaced by a plant or

109 libactin) is assembled, transported into the periplasm and cleaved to release the mature product(7-10

110 ependent conformational changes, in both the periplasm and cytoplasm of E. coli.

111 are thought to be distinctly located in the periplasm and cytoplasm respectively.

112 , four interconnected ring structures in the periplasm and cytoplasm, a cytoplasmic disc and dome, an

113 onnector between the stress responses in the periplasm and cytoplasm.

114 tsKN and other division proteins in both the periplasm and cytoplasm; thus, a clear understanding of

115 lding environment encountered by OMPs in the periplasm and demonstrate the key role of Skp in holding

116 tamase is functional in the Escherichia coli periplasm and enables the bacteria to survive treatment

117 Cellular compartments like periplasm and extracellular medium are difficult to pred

118 independent shuttling of the DNA through the periplasm and into the cytoplasm.

119 asm and involving FtsA, and the other in the periplasm and involving FtsQLB.

120 mH is involved in the import of DNA into the periplasm and its delivery to the inner membrane translo

121 PgaB is located in the periplasm and likely bridges the inner membrane synthesi

122 As these complexes traverse the periplasm and link inner and outer membranes, it remains

123 aggregation-prone curli subunits across the periplasm and outer membrane, and coordinates subunit se

124 s a two-domain protein that localizes to the periplasm and outer membrane.

125 transferring reducing power to the oxidizing periplasm and protecting against copper stress by cooper

126 dues at the substrate entry site towards the periplasm and provide a model for polysaccharide translo

127 e determined that MarP is located in the Mtb periplasm and showed that this localization is essential

128 nding proteins (PBPs) that bind cargo in the periplasm and shuttle it to an ATP-binding cassette (ABC

129 g disulfide bond generation in the bacterial periplasm and suggests that the strategy of linked disul

130 toxic when targeted to the Escherichia coli periplasm and that it depolarizes the cytoplasmic membra

131 lA to the PEL secretion apparatus within the periplasm and that this may allow for efficient deacetyl

132 the F0 proton half-channels that access the periplasm and the cytoplasm are exposed to the same pH,

133 due to protection of the nucleic acid by the periplasm and the extensive cell aggregation that we obs

134 OspC/Vsp1 surface lipoproteins traverse the periplasm and the outer membrane as unfolded monomeric i

135 ciate with additional subunits to bridge the periplasm and the outer membrane.

136 be involved in copper detection in both the periplasm and the thylakoid lumen.

137 in signal transduction between cytoplasm and periplasm and the transition from ExbB homodimers to hom

138 conduit connecting the sensing event in the periplasm and the unleashing of resistance mechanisms in

139 r-membrane proteins (OMPs) accumulate in the periplasm and their C-terminal peptides activate DegS by

140 itional cytoskeletons, CrvA localizes to the periplasm and thus can be considered a periskeletal elem

141 a low false negative rate, particularly, on "periplasm" and "extracellular medium".

142 fibrillar state of CsgA within the bacterial periplasm, and upon recruitment to the curli pore, CsgG,

143 sporter, consistent with modification in the periplasm, and was eliminated by deletion of the glucosy

144 the handling of the incoming DNA within the periplasm are poorly understood.

145 oligosaccharides that after transport to the periplasm are processed by BoGal36A.

146 d that paramagnetic spin labels entering the periplasm are selectively reduced to achieve specific la

147 g the phage to be drawn into the V. cholerae periplasm as an extension of the pilus filament.

148 lasmic Fes and IroD, Cee is localized in the periplasm as demonstrated by immunoblotting using Cee-sp

149 rel folding by the Bam complex begins in the periplasm at the membrane interface.

150 logical and alkaline pH, while entrapment in periplasm at weakly acidic pH and retention in external

151 s cells that import enterobactin only to the periplasm become morphologically aberrant.

152 The peptidoglycan wall, located in the periplasm between the inner and outer membranes of the c

153 het model where binding of chaperones in the periplasm biases DNA diffusion through a membrane pore i

154 otect the polymer as it passages through the periplasm but that it also plays a role in alginate acet

155 ufficient for the accumulation of DNA in the periplasm, but not for DNA internalisation into the cyto

156 sembly is therefore not only arrested in the periplasm, but the preservation of conformational flexib

157 in lacking a classical signal peptide to the periplasm by a SecA-dependent, but SecB-independent targ

158 y, which releases secreted proteins into the periplasm by cleaving the inner membrane-bound leader.

159 n aromatic chromophore that is formed in the periplasm by intramolecular cyclization steps.

160 o serine resulted in release of OPH into the periplasm, confirming that OPH is a lipoprotein.

161 antibiotic-treated bacterial cells to obtain periplasm, cytoplasm, and membrane fractions of high pur

162 ligosaccharides are further processed in the periplasm, degalactosylated by BoGal36A, and subsequentl

163 suggests how LptD/E can insert LPS from the periplasm directly into the outer leaflet of the OM to e

164 facilitate glycosaminoglycan import into the periplasm; distinct kinetic and genetic specificities of

165 ted Q-site (Q(D)) to proton release into the periplasm during anaerobic respiration.

166 f FBPase were in the extracellular fraction (periplasm) during glucose starvation.

167 When exported to the Escherichia coli periplasm, each domain disrupted cell growth, and combin

168 te membrane reorganization, during which the periplasm extrudes into a mega outer membrane vesicle or

169 large cytoplasm-facing funnel and a smaller periplasm-facing funnel.

170 the structural architecture of an alternate, periplasm-facing state.

171 he inner-membrane-bound Sec machinery to the periplasm, followed by secretion across the outer membra

172 c N-terminal domains that reach out into the periplasm for communication with the inner membrane plat

173 diated processing of prepilin amassed in the periplasm for rapid pilin elaboration and subsequent BRP

174 arriers to transport cargo proteins into the periplasm for storage during glucose starvation.

175 n this pathogen may confer protection of the periplasm from copper-mediated damage while sustaining v

176 entire sequence of events that occurs in the periplasm from the unfolded-reduced state to the folded-

177 P(i) because bacteria accumulate P(i) in the periplasm, from which it can be removed hypo-osmotically

178 ansmembrane domains and a globular domain in periplasm has been recently identified as a CL transport

179 brane to impede entry of vancomycin into the periplasm, hindering access to its target, an intermedia

180 r the aqueous interface of UppP and face the periplasm, implicating that its enzymatic function is on

181 ally not found in bacteriocins targeting the periplasm, implying a specific role in translocating the

182 evoid of export signals, are escorted to the periplasm in a piggyback fashion by the Tat signal pepti

183 -membrane transporters and imported into the periplasm in a process dependent on the inner-membrane p

184 the membrane until it is translocated to the periplasm in a subsequent step involving the electrochem

185 TMCM) enables its efficient transport to the periplasm in Corynebacterium glutamicum and that acetyla

186 o four fractions, namely the outer membrane, periplasm, inner membrane, and cytoplasm, and we observe

187 be useful in removing O2 from the bacterial periplasm; instead, the four-electron reduction of molec

188 r transmembrane helices that protrude in the periplasm into a binding domain for interaction with the

189 hus only needs to transport protons from the periplasm into the active site without the requirement t

190 ovo disulfide bond generation in the E. coli periplasm involves a transient complex consisting of Dsb

191 and Ag(I) ions; this system, located in the periplasm, involves four proteins, CusA, CusB, CusC, and

192 radical in both cytosol and thylakoid lumen/periplasm irrespective of the N-status of growth by regu

193 As the periplasm is an oxidizing environment as compared with t

194 mbranes through the hydrophilic space of the periplasm is not known.

195 ys in attachment to the peptidoglycan of the periplasm is unknown.

196 Because the periplasm lacks ATP, the source of energy that drives pa

197 Because the periplasm lacks ATP, vectorial folding of the passenger

198 bacteriocin is required for activity in the periplasm leading to hydrolysis of peptidoglycan.

199 dicating a delivery mechanism by which these periplasm-located yet immunogenic glycoproteins can inte

200 arge number of flagella and the absence of a periplasm make B. subtilis a premier organism for the st

201 some components in the relatively accessible periplasm make it an attractive target for the developme

202 o of 3:6:3 CusA/CusB/CusC to form the CusCBA periplasm membrane transporter.

203 ) was taken up and found associated with the periplasm, membrane or cytoplasm fractions of the cells.

204 ivers AmpDh3 (but not AmpD or AmpDh2) to the periplasm of a prey bacterium upon contact.

205 lymerization of a major pilin protein in the periplasm of a wide range of bacteria and archaea.

206 he lumen of the endoplasmic reticulum or the periplasm of bacteria is mediated by a highly conserved

207 metallic Cu,Zn-SODs are widespread, from the periplasm of bacteria to virtually every organelle in th

208 t CdiA-CT toxins can be transferred into the periplasm of de-energized target bacteria, indicating th

209 Here we show that an assay in the periplasm of E. coli linking aggregation directly to ant

210 ith slightly substoichiometric zinc from the periplasm of Escherichia coli and is capable of binding

211 several site-directed mutant proteins in the periplasm of Escherichia coli facilitated a detailed in

212 oxification of copper and silver ions in the periplasm of Escherichia coli.

213 o further study folding and targeting in the periplasm of Escherichia coli.

214 in the presence of mammalian cells or in the periplasm of Escherichia coli.

215 rol degradation of misfolded proteins in the periplasm of gram-negative bacteria and is required for

216 ed proteins are known to be delivered to the periplasm of Gram-negative bacteria, the growth medium o

217 rm in vivo as the entry domain dwells in the periplasm of inhibitor cells prior to target-cell recogn

218 cretion exported 3) can be injected into the periplasm of neighboring bacterial competitors by a Type

219 Predatory Bdellovibrio bacteria invade the periplasm of other bacterial prey cells, usually crossin

220 PldB targets the periplasm of prokaryotic cells and exerts an antibacteri

221 We isolated FlhE from the periplasm of Salmonella and solved its structure to 1.5A

222 known about how PF are assembled within the periplasm of spirochaetal cells.

223 ved from the effector upon transfer into the periplasm of target bacteria.

224 ion domain and degrades peptidoglycan in the periplasm of target bacteria.

225 The periplasm of the DeltanlpA DeltadegP strain was determin

226 e crowded electron transport proteins in the periplasm of the organism constituted an electron conduc

227 to kill E. coli cells when addressed to the periplasm of these bacteria.

228 Ccps are located in the periplasms of bacteria and the mitochondrial intermembra

229 t with OspC mutants that mislocalized to the periplasm or contained C-terminal epitope tags.

230 could attack substrates found either in the periplasm or cytosol of target bacteria.

231 membrane with the lipoprotein domain in the periplasm or outside the cell.

232 Rv0203 transports heme across the bacterial periplasm or scavenges heme from host heme proteins, Mmp

233 polysaccharides)--in the form of cell walls, periplasms or gel-like matrices--are ubiquitously presen

234 tion, the tail tube penetrates the host cell periplasm, pausing while it degrades the peptidoglycan l

235 ure that consists of the inner membrane, the periplasm, peptidoglycan and the outer membrane, and pro

236 remature amyloidogenesis within the cellular periplasm, preventing early aggregation and cellular tox

237 r of changes of individual cell membrane and periplasm properties of live E. coli cells in response t

238 CTXPhi transit across the bacterial periplasm requires binding between the minor coat protei

239 ith the N and C termini in the cytoplasm and periplasm, respectively.

240 ant of R. l. bv. viciae exported SodA to the periplasm, ruling out export of SodA as a complex with a

241 a decrease in the oxidizing activity of the periplasm stimulates PhoQ/PhoP and may reveal a new inpu

242 mediate phospholipid trafficking across the periplasm, such as MCE (Mammalian Cell Entry) transporte

243 hydrolysis is coupled to transport into the periplasm, such that little to no low-molecular weight (

244 nking of TM2 and the connected region in the periplasm suggest a piston-type shift of TM2 by four res

245 ward the membrane or push it down toward the periplasm, suggesting a possible mechanism for providing

246 C-terminal domain of CpaB is exposed to the periplasm, suggesting that this is the site where CpaA a

247 ires as extensions of the outer membrane and periplasm that include the multiheme cytochromes respons

248 contain an N-terminal module located in the periplasm that includes two polypeptide transport-associ

249 gments fold into a trimeric structure in the periplasm that persists until the termination of passeng

250 ns of the cytochrome-rich outer membrane and periplasm that, when dried, collapse to form filaments w

251 Dsb (disufide bond) system of the bacterial periplasm, the compartment from which the IMS was derive

252 hat, following delivery of CdiA-CTs into the periplasm, the N-terminal domains bind specific inner-me

253 terminus of bound-form Lpp is located in the periplasm, the precise location of free-form Lpp has nev

254 cessive l-cysteine from the cytoplasm to the periplasm, thereby maintaining redox homeostasis.

255 m Rcs component, for RcsF binding across the periplasm, thereby regulating the Rcs response.

256 ding subunits and are bulk components of the periplasm, they represent a Ca(2+) capacitor discharged

257 YbcL requires liberation from the bacterial periplasm, though the mechanism of release is undefined.

258 at establishes an energy gradient across the periplasm, thus driving their sorting by chaperones to t

259 ed to 27 and 24 kDa forms in the cytosol and periplasm/thylakoid lumen.

260 zing entering protons and thus buffering the periplasm to a pH of roughly 6.1 even in gastric juice a

261 F C-terminal signaling domain located in the periplasm to activate the stress response.

262 conformational changes via SecDF across the periplasm to BAM.

263 module TamB to nucleate proper folding from periplasm to cell surface through a cooperative mechanis

264 zed role in transport of inorganic iron from periplasm to cytoplasm, FtrABCD system function did not

265 ) family of serine proteases function in the periplasm to degrade damaged or improperly folded membra

266 it along a filament that extends across the periplasm to directly deliver lipopolysaccharide into th

267 in the transition from rod completion in the periplasm to extracellular hook polymerization.

268 (c20) was isolated directly from S. meliloti periplasm to identify its N-terminal amino acids and the

269 his supports a model in which LpoB spans the periplasm to interact with PBP1B and stimulate PG synthe

270 he cuprous oxidase CueO is secreted into the periplasm to oxidize the more membrane-permeable and tox

271 single pathway for proton delivery from the periplasm to the active site that is shared by all cNORs

272 the secretion of substrate proteins from the periplasm to the cell exterior.

273 move LPS from the inner membrane through the periplasm to the cell surface.

274 confirm that LptD/E transports LPS from the periplasm to the external leaflet of the outer membrane.

275 is required for CDI toxin transport from the periplasm to the target-cell cytoplasm.

276 rather requiring them to be converted in the periplasm to their respective sugar acid forms before tr

277 on-type shift of TM2 by four residues to the periplasm upon activation (or fumarate binding).

278 f TM2 by four residues (or 4-6 A) toward the periplasm upon activation is complementary to the peripl

279 uild a peptidoglycan (PG) cell wall in their periplasm using the precursor known as lipid II.

280 Our data indicated that, in the periplasm, various periplasmic and peripheral membrane e

281 transit from the bacterial cytoplasm to the periplasm via an inner-membrane pore complex (TraC and T

282 minus in the cytoplasm and C-terminus in the periplasm, was much more particular, requiring an intact

283 port cannot explain P(i) accumulation in the periplasm we propose that periplasmic P(i) anions pair w

284 ep and HS oligosaccharides imported into the periplasm were degraded by a repertoire of lyases, with

285 enzyme binding and/or mass-transfer into the periplasm were rate-limiting.

286 TAT secretion signal, were able to reach the periplasm when expressed in the bacterial cytosol.

287 e that OMPs have a prolonged lifetime in the periplasm where an unfolded OMP makes, on average, hundr

288 Tat-dependent manner, delivering Bla to the periplasm where it hydrolyzed beta-lactam antibiotics.

289 mbled in the cytoplasm and exported into the periplasm where it undergoes considerable maturation, mo

290 ellular side of OmpF and translocates to the periplasm where the polypeptide chain does an about turn

291 then transported across the membrane to the periplasm where they act as donors for other reactions.

292 o leakage of unfolded FlaB proteins into the periplasm where they are degraded by HtrA, a protease th

293 ed) form of PhoP by removing Mg(2+) from the periplasm, where it functions as a repressing signal for

294 ses Hap to mislocalize and accumulate in the periplasm, where it is degraded by HtrA.

295 that LacZ can be fully translocated into the periplasm, where it is toxic.

296 s of Omp85 family members are located in the periplasm, where they interact with other partner protei

297 ng disulfide bond formation in the bacterial periplasm, which is topologically equivalent to the plas

298 r expressing these proteins in the bacterial periplasm with the help of signal peptide paves the way

299 ance distribution of spin label pairs on the periplasm with those calculated using inward- and outwar

300 orm is overcome by PulC linkers spanning the periplasm, with PulC HR domains binding independently at