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1 the only Ln-proteins identified to date are periplasmic.
2 e, although BoMan26A and BoGal36A are likely periplasmic.
5 mplex machinery comprised of outer membrane, periplasmic adaptor, and inner membrane protein componen
6 -ATPase proton pump efflux that dissociates periplasmic AGP-Ca(2+) resulting in a Ca(2+) influx that
9 nduced displacement of an alpha helix in the periplasmic and transmembrane domains, but it is unknown
10 y which OprM is activated via opening of its periplasmic aperture through a concerted interaction wit
11 novel Hechtian oscillator that integrates a periplasmic arabinogalactan glycoprotein-calcium (AGP-Ca
12 rface endo-1,6-beta-glucanase, BT3312, and a periplasmic beta-glucosidase that targets primarily 1,6-
13 o results show that MtrE can be regulated by periplasmic binding events and that the interaction betw
14 or that, together with its integral membrane periplasmic binding partner ToxS, is conserved across th
15 h-throughput method relies upon the thiamine periplasmic binding protein (TBP) from Escherichia coli
18 orescence spectroscopy showed that MatC, the periplasmic binding protein from this system, binds to l
20 e pathogenicity and are mediated through the periplasmic binding protein NspS and the transmembrane b
23 structures and ligand binding affinities of periplasmic binding proteins from bacterial phosphite an
24 the potential for using genetically encoded periplasmic binding proteins such as RBP to measure meta
26 nts and imported into the bacterial cell via periplasmic-binding proteins (PBPs) and ABC-transporters
29 ght-transmembrane helix fold that supports a periplasmic carbon-nitrogen hydrolase domain containing
30 esent crystal structures revealing the MCR-1 periplasmic, catalytic domain to be a zinc metalloprotei
32 formation in which an aromatic belt near the periplasmic channel exit seals the transporter in a rest
34 RND) system) and of a putative Cu(+)-binding periplasmic chaperone and the unusual presence of two cy
36 s thought to explain the essentiality of the periplasmic chaperone LolA and its OM receptor LolB that
39 asmic protein stability over external pH and periplasmic chaperone protection mechanisms, and 3) chan
43 ved chaperone-usher (CU) pathway, in which a periplasmic chaperone works together with an outer membr
45 of membrane thickness, the Escherichia coli periplasmic chaperones Skp and SurA, and BamA, the centr
46 apidly and were effectively engaged by fewer periplasmic chaperones than their urea-denatured counter
47 gram-negative bacteria involves delivery by periplasmic chaperones to the beta-barrel assembly machi
48 e through the Sec-translocon for delivery to periplasmic chaperones, for example SurA, which prevent
49 of the pilus and then taken up by binding to periplasmic ComEA, acting as a Brownian ratchet to preve
51 lls), but owing to the smaller volume of the periplasmic compartment, its concentration in the cytopl
52 he 1.56 angstrom resolution structure of the periplasmic complex of the C-terminal CSS domain (CCSSD)
54 brane efflux protein TolC and with PstS, the periplasmic component of the ABC transporter complex (Ps
55 , the structure, assembly and roles of other periplasmic components remain enigmatic, limiting our kn
56 ia acquire phosphate (P(i)) by maintaining a periplasmic concentration below environmental levels.
57 ux kinetics through the determination of its periplasmic concentrations by quantitation of the first
58 cal BAM pathway, while formation of a stable periplasmic conformer involves an export-related, foldin
62 al envelope-restricts the expression of this periplasmic copper resistance protein solely to cells en
64 u and the high-affinity CcoI feeds Cu into a periplasmic Cu relay system required for cbb(3) -Cox bio
65 ane transporters, whereas CopR/S responds to periplasmic Cu(+) Analysis of DeltacopR and DeltacueR mu
66 a CopR regulon composed of genes involved in periplasmic Cu(+) homeostasis and its putative DNA recog
69 on flow from sulfide to oxygen that involves periplasmic cytochromes, yet-unidentified conductive per
71 Cytochrome c nitrite reductase (ccNiR) is a periplasmic, decaheme homodimeric enzyme that catalyzes
73 y, nickel import ATP-binding protein (NikE), periplasmic dipeptide transport protein (DppA), and oute
75 velocity depends on the concentration of the periplasmic DNA-binding protein ComE, indicating that Co
76 and produced a soluble version of AcrB [AcrB periplasmic domain (AcrBper)], which is highly congruent
77 o 190) is essential for viability, while the periplasmic domain (residues 191 to 586) is dispensable.
78 d LptG are composed of a beta-jellyroll-like periplasmic domain and six alpha-helical segments in the
79 How the inner membrane protein YejM with its periplasmic domain changes membrane properties remains u
81 r supported by results showing that the ToxR periplasmic domain contributed to indole-mediated increa
82 e pbgADelta191-586 mutant (in which the PbgA periplasmic domain from residues 191 to 586 is deleted).
83 esent the 2.1 angstrom structure of the FtsX periplasmic domain in complex with its periplasmic partn
84 ish that RcsF interacts with the C-terminal, periplasmic domain of OmpA, not with the N-terminal beta
85 pair in which the electron transfer from the periplasmic domain of ScsB (n-ScsB) to ScsC is thermodyn
87 rotein allows the interaction of ComH with a periplasmic domain of the inner-membrane channel ComEC,
89 se requires that at least one subunit of the periplasmic domain of the Tsr homodimer (pTsr) has an in
91 PelB, a membrane-embedded porin with a large periplasmic domain predicted to contain 19 tetratricopep
92 ToxRp to have a higher affinity for the ToxS periplasmic domain than the non-disulfide bonded conform
93 2 gene product contains a ~200-aa N-terminal periplasmic domain that is anchored in the membrane by t
100 rane 'insertase' YidC - contacts BAM through periplasmic domains of SecDF and YidC, ensuring efficien
102 erwhelming structural similarity between the periplasmic domains of two YejM homologues with hydrolas
104 mains drives opening and closing of the MacB periplasmic domains via concerted movements of the secon
105 f Ca(2+) with a wide-open pore and remodeled periplasmic domains, including increased contacts betwee
111 hydrophobic cavity toward the transporter's periplasmic domains.Lipopolysaccharides (LPS) are synthe
113 ogical membrane, lipid molecules occupy this periplasmic exit and prevent water flux in the transport
118 dant outer membrane lipoprotein, Lpp, at the periplasmic face of the inner membrane leads to lethal i
121 ate that the double labeling of sites on the periplasmic-facing surface of BtuB is possible using a d
122 mic cytochromes, yet-unidentified conductive periplasmic fibers, and periplasmic oxygen reduction.
124 ease bacterium Borrelia burgdorferi has 7-11 periplasmic flagella (PF) that arise from the cell poles
125 gy with hook-shaped ends and the presence of periplasmic flagella (PF) with pronounced spontaneous su
126 investigated the role played by T. denticola periplasmic flagella (PF), unique motility organelles of
129 ike flagella of other bacteria, spirochetes' periplasmic flagella possess a complex structure called
130 pathogenicity; indeed, spirochaete flagella (periplasmic flagella) reside and rotate within the perip
131 hete, and motility, which is provided by its periplasmic flagella, is critical for every part of the
137 pathogen, Campylobacter jejuni, possesses a periplasmic formate dehydrogenase and two terminal oxida
138 equent electron transfer could proceed via a periplasmic formate dehydrogenase and/or hydrogenase, al
141 the first two crystal structures of soluble periplasmic globular domain of PbgA from S. typhimurium
143 first high resolution crystal structures of periplasmic glucose-binding protein fromPseudomonas puti
144 have developed probes based on the bacterial periplasmic glutamate/aspartate binding protein with eit
145 rprising discovery that the Escherichia coli periplasmic glycerol-3-phosphate (G3P)-binding protein U
146 are consistent with the conclusion that the periplasmic half-channel is more easily protonated in a
147 es acidification through protonation of CpxA periplasmic histidine residues, and upregulates the fabA
148 ToxR requires its operon partner ToxS, a periplasmic integral membrane protein, for full activity
149 dhesion proteins of the outer membrane via a periplasmic interaction platform, which presumably invol
150 Both the ATPase activity of FtsEX and its periplasmic interaction with EnvC are required for amida
151 Both the ATPase activity of FtsEX and its periplasmic interaction with EnvC are required for resis
154 flet of the inner membrane is flipped to the periplasmic leaflet by MsbA, an ATP-binding cassette tra
155 rane on a lipid anchor and reoriented to the periplasmic leaflet by the channel-forming WzmWzt ABC tr
157 binds deep inside MsbA at the height of the periplasmic leaflet, establishing extensive hydrophilic
159 from the nitrilase domain interacts with the periplasmic lipid leaflet, forming an interfacial entran
160 a gene, virJ, that codes for a protein with periplasmic localization that is involved in the intrace
163 ach, we demonstrate that LpqN interacts with periplasmic loop domains of the MmpL3 and MmpL11 transpo
164 ng binds and the other located in the second periplasmic loop of DsbB, which interacts with DsbA.
165 tutions in transmembrane domains 2 and 8 and periplasmic loops of MurJ could be cross-linked with hom
166 er contains 12 transmembrane helices and two periplasmic loops that suggest a plausible pathway for s
167 kinetic and genetic specificities of various periplasmic lyases which dictate glycosaminoglycan metab
169 in modifications are well characterized, the periplasmic maturation steps are far from understood.
172 de two routes for methylamine oxidation: the periplasmic methylamine dehydrogenase (MaDH) and the cyt
173 tric and electronic structure of the E. coli periplasmic molybdenum-dependent methionine sulfoxide re
174 MS also identified candidate partners for periplasmic MOSP, including TDE1658, a spirochete-specif
175 d by a localized 16-mer stoichiometry in the periplasmic-most coupling domain of the otherwise 15-mer
176 of a respiratory arsenate reductase (arrA), periplasmic nitrate reductase (napA) and membrane-bound
177 iated growth inhibition, whereas all but the periplasmic nitrite reductase NrfA provide protection ag
178 e Escherichia coli K-12 nrf operon encodes a periplasmic nitrite reductase, the expression of which i
179 ulfofustis deltaproteobacterium, including a periplasmic NTD fused to the conventional ligand-binding
182 itrosoglutathione (GSNO) in vitro However, a periplasmic or extracellular denitrosylase has not been
185 actin, and their fluorophore is generated by periplasmic oxidation and cyclization reactions of d-tyr
189 ccumulation in the periplasm we propose that periplasmic P(i) anions pair with chemiosmotic cations o
191 single H(+)-driven stator have only the core periplasmic P- and L-rings; those with dual H(+)-driven
193 ch is highly congruent in structure with the periplasmic part of the full-length protein, and is capa
196 ia coli, a proteolytic system comprising the periplasmic PDZ-protease Prc and the lipoprotein adaptor
197 C transporter that regulates the activity of periplasmic peptidoglycan amidases via its interaction w
200 upon cellular demand while still maintaining periplasmic plasticity; this could be broadly relevant t
202 he predatory behaviour of two strains of the periplasmic predator B. bacteriovorus and of the epibiot
205 ies have established the essentiality of the periplasmic protease MarP for Mtb to survive in acidifie
208 ed by LapD, a c-di-GMP receptor, and LapG, a periplasmic protease, which together control whether Lap
209 from the inner membrane and places it onto a periplasmic protein bridge through a poorly understood m
210 a coli disulfide bond formation pathway, the periplasmic protein DsbA introduces disulfide bonds into
214 es and chaperones exhibit important roles in periplasmic protein quality control and stress responses
216 e lipid fatty acid composition, 2) change in periplasmic protein stability over external pH and perip
218 uter membrane MlaA-OmpC/F complex, a soluble periplasmic protein, MlaC, and the inner membrane ATPase
222 Two general groups - metalloproteins and periplasmic proteins - show enrichment of their antioxid
223 NAs encoding outer-membrane, cytoplasmic and periplasmic proteins are distributed throughout the cyto
225 to be specifically involved in the repair of periplasmic proteins oxidized by hypochlorous acid.
227 n protein, connecting MmpL transporters with periplasmic proteins, and provide general insight into t
230 Here we identify the protein ComH as the periplasmic receptor for the transforming DNA during nat
231 ant predators can replicate unusually in the periplasmic region between the peptidoglycan wall and th
232 uorimetry showed interaction of the isolated periplasmic region of McpX (McpX(PR) and McpX34-306 ) wi
233 olves association of the plug helices in the periplasmic region of the MotB dimer into a parallel coi
235 s with most of the transmembrane helices and periplasmic regions of SecY, with a clustering of intera
239 cterial flagellar motor, including two novel periplasmic ring structures, and the stator ring harbori
240 sought to determine whether PelB serves as a periplasmic scaffold that recruits other components of t
241 s direct interactions with transmembrane and periplasmic segments, as well as peripheral interactions
243 experiments uncover a model in which direct periplasmic sensing of LPS by PbgA coordinates the biosy
244 hosphatase domain but also contains a unique periplasmic sensor domain that is expected to control th
247 he interfacial metal-binding sites in CusS's periplasmic sensor domains, prior to ATP binding and aut
252 polysaccharides (LPS) are synthesized at the periplasmic side of the inner membrane of Gram-negative
253 within the lumen of an OmpF subunit from the periplasmic side of the membrane, a binding mode reminis
258 at rod length is limited by the width of the periplasmic space between the inner and outer membranes.
259 d that their small size and relatively large periplasmic space might enable them to outcompete other
260 y coexpressing 3 recombinant proteins in the periplasmic space of Escherichia coli-an antibody clone,
264 cetes, including a defined outer membrane, a periplasmic space that can be greatly enlarged and convo
266 of moving Braun's lipoprotein (BLP) from the periplasmic space to the outer membrane of E. coli, via
267 ipids are exported from the cytoplasm to the periplasmic space via the mycobacterial membrane protein
269 hich polar substrates move directly into the periplasmic space, PpF1 TodX and CymD direct their hydro
281 , which is able to bind both Hep and HS, and periplasmic sulfatases reveal the major specificity dete
288 ther proteobacteria that we termed PtaA for "periplasmic transaminase A" An in-frame-deleted ptaA mut
290 verdine-producing bacteria, its catalysis of periplasmic transaminations is most likely a general too
292 us influenzae use tripartite ATP-independent periplasmic transporters (TRAPs) to scavenge sialic acid
293 proteins, including overwhelmingly abundant periplasmic transporters for nutrient acquisition and pr
295 OSP in TDE exists as outer membrane (OM) and periplasmic trimeric conformers; PelB-MOSP, in contrast,
297 e inner membrane, the T2SS has a much longer periplasmic vestibule and it has a short-lived flexible
298 that this discrepancy can be resolved if the periplasmic volume decreases as the cell wall becomes so
300 The length of Braun's lipoprotein determines periplasmic width by tethering the outer membrane to the