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1 ced pex4 defects, confirming that PEX22 is a peroxin.
2 p, and the intraperoxisomal presence of this peroxin.
3 d that the encoded protein, Pex22p, is a new peroxin.
4 ng and subsequent budding of the RING-domain peroxins.
5 suggesting distinct roles of individual RING peroxins.
6  PEX13 and possibly PEX14 and all three RING peroxins.
7 ikely to require interaction with additional peroxins.
8 , showing distinct differences between these peroxins.
9 hich is required for recognition by the AAA+ peroxins.
10 on requires the peroxisomal membrane protein Peroxin 11 (Pex11p), which remodels the membrane, result
11  stimuli such as arsenic and is regulated by peroxin 11a (PEX11a), as Arabidopsis pex11a RNAi lines a
12                                  Homologs of peroxin 16 genes (PEX16) have been identified only in Ya
13 ort that the peroxisomal E3 ubiquitin ligase peroxin 2 (PEX2) is the causative agent for mammalian pe
14    The predicted Gim1 protein is related the peroxin 2 family of integral membrane proteins, which ar
15                                              Peroxin 5 (PEX5), the peroxisomal protein shuttling rece
16 signal recognition by the cytosolic receptor peroxin 5 (PEX5).
17 uman MCD onto the peroxisomal import protein peroxin 5, which revealed interactions that extend beyon
18  have revealed numerous Arabidopsis thaliana peroxins acting in peroxisomal matrix protein import; th
19 4p, Pex17p) and RING (Pex2p, Pex10p, Pex12p) peroxins and is also implicated in cargo release of PTS1
20 the peroxisome membrane via interaction with peroxins, and during pexophagy it colocalizes transientl
21                                              Peroxins are genetically defined as proteins necessary f
22 5 with peroxisomes, demonstrating that these peroxins are not required for receptor docking.
23                                              Peroxins are proteins involved in peroxisome, glycosome
24        Although at least 20 proteins (mostly peroxins) are required for peroxisome biogenesis, the ro
25  (Pp) Pex8p, the only known intraperoxisomal peroxin at steady state, is targeted to peroxisomes by e
26 Mutations in peroxisome biogenesis proteins (peroxins) can lead to developmental deficiencies in vari
27 etermine whether destabilization of the RING peroxin complex observed in pex12-1 stems from PEX4-depe
28 kes the functional characterization of human peroxins critical.
29                      Altered activity of the peroxin defective in CG7 cells leads to accumulation of
30  PTS1 receptor was extremely unstable in the peroxin-deficient CG1, CG4, and CG8 cells.
31 as of progress are the identification of new peroxins, definition of protein-protein interactions amo
32 Peroxisomal defects were exacerbated in RING peroxin double mutants, suggesting distinct roles of ind
33  and that AMC functions in gametophytes as a peroxin essential for protein import into peroxisomes.
34 indicating that they constitute a two-member peroxin family specifically required for Pex7p and PTS2
35 he adrenoleukodystrophy-related gene and the peroxin gene, PEX11alpha, was found in PBD fibroblasts.
36 uing possibility that other "yeast-specific" peroxins have eluded discovery in plants and mammals bec
37 ome biogenesis to the parasite, render these peroxins highly promising drug targets.
38 ummary, AtPex16p is the only authentic plant peroxin homolog known to coexist at steady state within
39 eptor PEX5 and is the most commonly affected peroxin in human peroxisome biogenesis disorders.
40 es, aspects of import/biogenesis the role of peroxins in human disease, and involvement of the endopl
41 he elucidation of the role of many conserved peroxins in human disease.
42            Unlike the roles of specific RING peroxins in Pex5 ubiquitination, we found that all the R
43 7 levels, supporting the involvement of RING peroxins in receptor ubiquitination in Arabidopsis.
44 ort of peroxisomal enzymes is facilitated by peroxins including PEX5, a receptor that delivers cargo
45                            Furthermore, this peroxin interacts with Pex5p and Pex13p(SH3) and is dire
46                          PEX14 and PEX13 are peroxins involved in docking cargo-receptor complexes at
47 ling was used to identify PEX genes encoding peroxins involved in peroxisome assembly and genes invol
48                                        Among peroxins involved in peroxisome biogenesis, only Pex8p i
49              This includes mutants that lack peroxins involved in receptor docking at the membrane (D
50 resenting a defect in a peroxisomal protein (peroxin) involved in peroxisome biogenesis.
51     The identification of vesicle-associated peroxins is novel and implies a role for these vesicles
52 ng that PEX1, like several other Arabidopsis peroxins, is essential for embryogenesis.
53 nition of protein-protein interactions among peroxins leading to the recognition of complexes involve
54 rved that disruption of any Arabidopsis RING peroxin led to decreased PEX10 levels, as seen in yeast
55 ation and characterization of an Arabidopsis peroxin mutant, pex7-1, which displays peroxisome-defect
56 tination-related mutants and found that RING peroxin mutants displayed elevated PEX5 and PEX7 levels,
57                                          Two peroxins of the AAA family, PpPex1p and PpPex6p, are req
58  matrix protein import, suggesting that this peroxin pair may have novel plant targets in addition to
59                Several peroxisome biogenesis PEROXIN (PEX) genes encode proteins acting in the import
60  required enzymes from the cytosol through a peroxin (Pex) import system.
61                                              Peroxin (PEX) proteins generate and maintain peroxisomes
62 y enzymes enter peroxisomes with the help of peroxin (PEX) proteins is increasing, mechanisms by whic
63 amoeba balamuthi We found a conserved set of peroxin (Pex) proteins that are required for protein imp
64 eroxisome biogenesis require the function of peroxin (PEX) proteins, among which PEX12 is a RING fing
65 rganelle matrix depends on more than a dozen peroxin (PEX) proteins, with PEX5 and PEX7 serving as re
66 ed into the organelle with the assistance of peroxin (PEX) proteins.
67  import proteins to the peroxisome matrix by peroxins (PEX proteins), but how the function of the PEX
68 teins from the cytosol through the action of peroxins (PEX proteins), many of which are conserved amo
69 isome division is regulated by the conserved peroxin Pex11p.
70  We also show that another integral PMP, the peroxin PEX13, also contains two independent sets of per
71 nterference (RNAi)-mediated knockdown of the peroxin PEX14.
72 ng complex PEX13-PEX14 and the (RING)-finger peroxin PEX2.
73 5 ubiquitination, we found that all the RING peroxins (Pex2, Pex10, and Pex12) are required as E3 ubi
74  (ER) sorting and budding of the RING-domain peroxins (Pex2, Pex10, and Pex12).
75 ors Pex8p, Pex10p, and Pex12p, and two other peroxins, Pex2p and Pex17p.
76                      We demonstrate that the peroxin Pex3 is not required for the formation of peroxi
77 ructure of the first three TPR-motifs of the peroxin PEX5 from Trypanosoma brucei, the causative agen
78 roxisomal biogenesis proteins (also known as peroxins (PEXs)) cause devastating disease.
79 1 gene, codes for a predicted 42-kD membrane peroxin protein (AtPex16p).
80 which the functional roles of many of the 23 peroxins (proteins involved in peroxisomal protein impor
81  study, we report that two integral membrane peroxins (proteins required for peroxisome biogenesis) i
82 8p and Pex21p are structurally related yeast peroxins (proteins required for peroxisome biogenesis) t
83          The role of most PEX gene products, peroxins, remains to be determined, but a variety of stu
84          Ypl112p, renamed Pex25p, is a novel peroxin required for the regulation of peroxisome size a
85 g signal (PTS1) receptor, one of at least 15 peroxins required for peroxisome biogenesis.
86 Pex18p and ScPex21p, two novel S. cerevisiae peroxins required for protein targeting via the PTS2 bra
87                                      Loss of peroxins required for protein translocation into the per
88 usly uncharacterized protein, is a cytosolic peroxin that facilitates the import of PTS2-containing p
89                                   Pex11 is a peroxin that regulates the number of peroxisomes in euka
90  GPT1 contacted two oxidoreductases and also peroxins that mediate import of peroxisomal membrane pro
91 EX genes and the altering of their proteins, peroxins, which are necessary for the importation of tar
92 e biogenesis is mediated by proteins called "peroxins," which are considered to be promising drug tar