ライフサイエンスコーパス: perpetuation

1 otein-based genetic elements capable of self-perpetuation.

2 B4 (LTB4), for disease induction as well as perpetuation.

3 LFA-1 I-domain adhesive function in disease perpetuation.

4 eans for adaptation, immune escape and virus perpetuation.

5 nt interneurons from contributing to seizure perpetuation.

6 tion (AF) contributing to its initiation and perpetuation.

7 ibution of each of these pathways to disease perpetuation.

8 hetic drive is less relevant to hypertension perpetuation.

9 that contribute to disease pathogenesis and perpetuation.

10 ontribution of each cytokine axis to disease perpetuation.

11 which on their own are not capable of tumor perpetuation.

12 ion growth and higher probability of species perpetuation.

13 activated lymphocyte survival, promoting its perpetuation.

14 ed, promoting novel mechanisms of arrhythmia perpetuation.

15 the atrium, which enhances AF complexity and perpetuation.

16 in AF and is considered the substrate for AF perpetuation.

17 ia, thus contributing to atrial fibrillation perpetuation.

18 ved to be involved in disease initiation and perpetuation.

19 ple contexts, and how they contribute to the perpetuation and dismantling of racial inequality.

20 uction has been invoked as the sole means of perpetuation and dispersal.

21 diverse and paradoxical roles for RTs in the perpetuation and elimination of genetic parasites.

22 ial scarring may be responsible for both the perpetuation and genesis of AF.

23 presence in live markets contributes to the perpetuation and genetic interaction of influenza viruse

24 storical factors best explain its subsequent perpetuation and growth?

25 The factors that regulate the perpetuation and invasiveness of rheumatoid synovitis ha

26 he SAM maintains a balance between stem cell perpetuation and organogenesis is a central question in

27 reproductive tract is essential for species perpetuation and overall health.

28 tory pathways involved in the establishment, perpetuation and removal of DNA methylation can lead to

29 sage of time and thus may play a role in the perpetuation and spread of these highly pathogenic H5N1

30 ve major implications regarding the relative perpetuation and survival of these two genotypes in mamm

31 Wildlife reservoirs play a role in perpetuation and transmission of this parasite to dogs.

32 isease, suggesting an involvement in disease perpetuation and/or chronicity.

33 ess essential for the controlled initiation, perpetuation, and resolution of inflammatory processes.

34 endogenous lectins can shape the initiation, perpetuation, and resolution of these processes, suggest

35 d monocytes contribute to the establishment, perpetuation, and resolution of tissue inflammation.

36 nding of the mechanisms of AF initiation and perpetuation, and rigorous integration of ablation into

37 Disease onset and perpetuation are mediated by peripherally generated auto

38 Perpetuation arises through focused attention, which fur

39 ect and behavior, (c) their transmission and perpetuation, (d) their alteration on the basis of first

40 iated by cell-mediated cytotoxicity with its perpetuation facilitated by alloantibodies.

41 hway as an important factor in myofibroblast perpetuation, fibrogenesis, and chronic disease progress

42 tion of the role of interleukin-6 in disease perpetuation has led to the use of an antihuman interleu

43 , highly purified HSCs and analyses of their perpetuation in clonally generated progeny HSCs have now

44 athways that potentially drive myofibroblast perpetuation in disease.

45 al remodeling leading to atrial fibrillation perpetuation is highly desirable.

46 are believed to be important triggers and a perpetuation mechanism for paroxysmal atrial fibrillatio

47 e that are part of a cultural system, to the perpetuation of a patient's disorder; the influence of f

48 repressive histone modifications results in perpetuation of a repressive chromatin state that contri

49 and aging in the germline are essential for perpetuation of a species; however, relatively few studi

50 r mechanisms involved in the development and perpetuation of acute spinal cord injury appear particul

51 rent data that pertain to the activation and perpetuation of adaptive immune responses during obesity

52 Rs during early abstinence contribute to the perpetuation of addiction to tobacco smoking.

53 rheumatoid arthritis (RA), especially in the perpetuation of advanced disease, remains unclear.

54 e linking inflammation to the initiation and perpetuation of AF and AF-related thrombosis.

55 the presence of a second factor in the self-perpetuation of AF with a time course comparable to that

56 of the immune system in the development and perpetuation of AF.

57 ant role in the initiation, maintenance, and perpetuation of AF.

58 chycardias may play an important role in the perpetuation of AF.

59 l role in initiating and contributing to the perpetuation of airway allergic inflammation.

60 t as effector cells in the initiation and/or perpetuation of airway inflammation in asthma by produci

61 e responses in the lung, contributing to the perpetuation of airway inflammation.

62 ion is a key component in the initiation and perpetuation of airway obstruction, the triggers underly

63 ies in decision-making neural systems in the perpetuation of AN.

64 ingly, mast cells become dispensable for the perpetuation of arthritis after delivery of IL-1, highli

65 ymphotoxin/LIGHT axis in the development and perpetuation of arthritis.

66 to play a central role in the initiation and perpetuation of autoimmune diseases such as multiple scl

67 y play important roles in the initiation and perpetuation of autoimmune responses, including conditio

68 acid mimics contribute to the initiation and perpetuation of autoimmunity by at first breaking self-t

69 e cytokines in SLE could be important in the perpetuation of B cell hyperactivity.

70 Perpetuation of breakage-fusion-bridge cycles in CML pro

71 CAV1 involved in the perpetuation of cell phenotype-overexpressing anti-stres

72 e elicitation of T effector function and the perpetuation of cellular immune responses.

73 gregation of intact genetic material and the perpetuation of chromatin states through mitotic cell di

74 tive stress may contribute indirectly to the perpetuation of chromosomal instability are discussed.

75 a critical role for epitope spreading in the perpetuation of chronic central CNS pathology.

76 ral pathogens, significantly contributing to perpetuation of chronic inflammation and tissue destruct

77 interleukin (IL)-11, IL-12, and IL-18 in the perpetuation of chronic inflammation continues to stimul

78 ponses, could collectively contribute to the perpetuation of chronic inflammation.

79 itis, especially if IL-17 is involved in the perpetuation of chronic or intermittent arthritis.

80 osters an environment for the development or perpetuation of comorbid conditions, or alternatively th

81 ed overeating, may in turn contribute to the perpetuation of compulsive eating behavior.

82 tor of the inflammatory cascade required for perpetuation of CRC, highlighting the IL-22 axis as a no

83 ost immune dysregulation plays a role in the perpetuation of Crohn's disease that can be corrected by

84 4+ T cells are essential for development and perpetuation of Crohn's disease, a chronic immune-mediat

85 mpelling mechanism for the amplification and perpetuation of DC-driven responses in the RA joint, inc

86 Thus, the perpetuation of DDR-2 expression and activation can be s

87 f infection, yet these cells are involved in perpetuation of different chronic inflammatory diseases.

88 lammation, tissue damage, carcinogenesis and perpetuation of disease and suppress the resolution of i

89 barrier (BBB) is critical to initiation and perpetuation of disease in multiple sclerosis (MS).

90 the roles of cytokines in the initiation and perpetuation of disease.

91 a and may contribute to both development and perpetuation of disease.

92 les of these molecules in the initiation and perpetuation of EAMG.

93 nderlying not only the genesis, but also the perpetuation of electric remodeling in the intact, fibri

94 omplement protein has been implicated in the perpetuation of epidemics caused by serotype M1 strains

95 ies of peer review in medical literature and perpetuation of erroneous science by unfiltered inclusio

96 ic bacteria populations in the induction and perpetuation of experimental colitis.

97 ion with previous studies, suggests that the perpetuation of expression of these factors affects seve

98 is pathway might blunt the initiation and/or perpetuation of extrafollicular humoral responses in SLE

99 We obtained evidence for the perpetuation of Fenton reactions in the presence of the

100 the Ras oncoprotein, is associated with the perpetuation of fibroblast activation and fibrogenesis i

101 ecular mechanisms, we hypothesized that this perpetuation of fibrogenesis is caused by epigenetic mod

102 BPs may be involved in the initiation and/or perpetuation of fibrosis by virtue of their ability to i

103 y type II pneumocytes, in the initiation and perpetuation of fibrosis in response to either endogenou

104 might be necessary during the evolution and perpetuation of FMDV in nature.

105 significant contributor to the severity and perpetuation of graft-versus-host disease.

106 ework provides a deeper understanding of the perpetuation of group-based inequality.

107 gh the indirect pathway is necessary for the perpetuation of GVHD.

108 live markets and create a situation for the perpetuation of H5N1 influenza viruses.

109 these vital mediators in the development and perpetuation of heart disease and the thromboinflammatio

110 te a significant amount of ATP to assure the perpetuation of heartbeats, multiple mechanisms are like

111 C) play a central role in the initiation and perpetuation of hepatic inflammation, which, if uncontro

112 d mechanisms that restrict the emergence and perpetuation of HP avian influenza viruses in these natu

113 mmune effector cells that contributes to the perpetuation of HSC activation in liver fibrosis through

114 The mechanisms responsible for perpetuation of human persistent atrial fibrillation (AF

115 dRP) or through genetic reassortment enables perpetuation of IAV in humans through epidemics or pande

116 gut-brain-axis has a central function in the perpetuation of IBS, and for this reason, it can be cons

117 ignificance of the IL-23/Th17 pathway in the perpetuation of IL-12/Th1-mediated immunopathology in PB

118 ibutes to the predisposition, initiation and perpetuation of immune-mediated diseases in the context

119 This raises concern about the potential for perpetuation of infection via medical procedures, in par

120 oinflammatory, which could contribute to the perpetuation of inflammation in patients with SLE.

121 Mechanisms causing the onset and perpetuation of inflammation in severe allergic patients

122 the diet-induced obese phenotype and for the perpetuation of inflammation in the hypothalamus.

123 The perpetuation of inflammation is an important pathophysio

124 Perpetuation of inflammation is an inherent risk because

125 s, and enzymes involved in amplification and perpetuation of inflammation.

126 of neutrophils but have also been linked to perpetuation of inflammation.

127 de overload, and subsequent exacerbation and perpetuation of inflammation.

128 mune cells contribute to the development and perpetuation of inflammatory bowel disease (IBD), namely

129 poptotic cells is frequently associated with perpetuation of inflammatory conditions.

130 ing the mechanisms behind the initiation and perpetuation of inflammatory processes in vasculitic neu

131 deregulation of Tregs may contribute to the perpetuation of inflammatory processes, including graft-

132 art transplant rejection and may account for perpetuation of inflammatory responses in the allograft,

133 iotic microbiota contribute to initiation or perpetuation of injury.

134 partial agonist with a potential role in the perpetuation of joint inflammation.

135 t and human, requires a mechanism for active perpetuation of L1 asymmetry during bursts of L1 activit

136 a multistep mechanism for the induction and perpetuation of lactotroph hyperplasia, involving the la

137 re likely to be critical for the genesis and perpetuation of leukemic disease, the present studies so

138 This pattern points to the perpetuation of linear thinking, despite the complex nat

139 is likely to contribute to the induction and perpetuation of liver damage in autoimmune hepatitis (AI

140 sfaction, play a role in the development and perpetuation of low back pain.

141 The data suggest that the perpetuation of many of the abnormal phenotypes associat

142 ndent TCR signals in regulating turnover and perpetuation of memory CD4 T cells and their responses t

143 em plays a pivotal role in the induction and perpetuation of metabolic and aging-related diseases.

144 put and regional development, as well as the perpetuation of migration corridors.

145 ific chromatin modifications that aid in the perpetuation of MLL fusion gene driven oncogenic program

146 mulation is necessary for both induction and perpetuation of mucosal inflammation and T-cell activati

147 thought to be critical in the initiation and perpetuation of multiple sclerosis disease activity.

148 cytoid DCs are central to the initiation and perpetuation of muscle inflammation in juvenile DM.

149 Inflammation plays a major role in the perpetuation of myopathy in degenerative muscle diseases

150 ing medical records is needed to prevent the perpetuation of negative bias in medical care.

151 t that fibrinogen in pEVs contributes to the perpetuation of neuroinflammation and relapses in diseas

152 ession program in microglia and blocking the perpetuation of neuroinflammation.

153 s a major component in the transition to and perpetuation of neuropathic pain states.

154 lay an important role in the development and perpetuation of obesity.

155 rdia may serve as a mechanism underlying the perpetuation of PAF.

156 oral microbiota underlying establishment and perpetuation of periodontitis.

157 tute a feedback loop that contributes to the perpetuation of poverty.

158 ls play a central role in the initiation and perpetuation of RA and are implicated in cartilage destr

159 for mucosal dysbiosis in the development and perpetuation of RA, although establishing whether these

160 g that clonal spread also contributes to the perpetuation of resistance.

161 Whether this contributes to the perpetuation of respiratory events and the pathogenesis

162 he form of angiogenesis, is important in the perpetuation of rheumatoid arthritis and, in the form of

163 which oligonucleosomal DNA may contribute to perpetuation of rheumatoid synovitis is proposed.

164 nes could escape subset-targeting therapy by perpetuation of self-reactivity in distinct subsets.

165 ical and structural remodeling contribute to perpetuation of simulated atrial fibrillation, using a m

166 nce, contributing to alcohol relapse and the perpetuation of smoking.

167 evaluation and deployment due to the risk of perpetuation of social disparities.

168 tive reactions to danger are critical to the perpetuation of species and are observed throughout the

169 sential for the initiation and, perhaps, the perpetuation of spontaneous autoimmunity.

170 ogenesis throughout their life cycle via the perpetuation of stem cell pools called shoot apical meri

171 of fibroblast-like synoviocytes (FLS) to the perpetuation of synovitis, we investigated the molecular

172 can have central roles in the initiation and perpetuation of systemic autoimmune disorders and orches

173 t to play a major role in the initiation and perpetuation of T helper cell, type 2 (Th2)-like allergi

174 tors are considered crucial to the onset and perpetuation of tendinopathy.

175 (T-bet, Tbx21) is pivotal for initiation and perpetuation of Th1 immunity.

176 lular signaling mechanisms of activation and perpetuation of the activated phenotype in HSCs are larg

177 creases immune activation, thus resulting in perpetuation of the activation/injury cycle.

178 and is responsible for the stabilization and perpetuation of the activity.

179 ntribute to the loss of immune tolerance and perpetuation of the autoimmune attack in AILD.

180 play an important role in the initiation and perpetuation of the autoimmune process.

181 Moreover, there is a concern that perpetuation of the belief that chronic cough is solely

182 velop an identical ciliary pattern, ensuring perpetuation of the cellular phenotype.

183 role of Escherichia coli in propagation and perpetuation of the chronic inflammation in ulcerative c

184 events in the intestinal cell necessary for perpetuation of the chronic inflammatory state.

185 o the CNS, where they may be crucial for the perpetuation of the CNS-targeted autoimmune response.

186 ycoprotein (MOG), has been implicated in the perpetuation of the disease state.

187 rom human skeletal myosin play a role in the perpetuation of the disease.

188 ovide valuable clues to the pathogenesis and perpetuation of the disease.

189 e grant review procedure, and illustrate the perpetuation of the funding gap, which contributes to th

190 e like, with meaningful implications for the perpetuation of the gender disparity that exists at the

191 r DNA after telomere damage is essential for perpetuation of the genetic information they carry.

192 tic functions and consider the potential for perpetuation of the imprint of experience through epigen

193 d arthritis) or T cells are required for the perpetuation of the inflammation at later stages as well

194 Initiation and perpetuation of the inflammatory intestinal responses in

195 ed lung tissue is an important target of the perpetuation of the inflammatory process occurring durin

196 tivity may thus critically contribute to the perpetuation of the inflammatory response in allergic co

197 tissues is fundamental to the initiation and perpetuation of the inflammatory state during immune and

198 cell properties and are responsible for the perpetuation of the myeloproliferative phenotype.

199 ell prior to cell division, thereby enabling perpetuation of the polar domain in future daughter cell

200 hat underlie the formation, recognition, and perpetuation of the polar domains are largely unknown.

201 may be required to prevent amplification and perpetuation of the rejection process.

202 quence of these competing classifications is perpetuation of the restrictive terms "coronary" and 'di

203 quence of these competing classifications is perpetuation of the restrictive terms 'coronary' and 'di

204 e either the sperm or eggs necessary for the perpetuation of the species.

205 rgans is critical for successful seedset and perpetuation of the species.

206 ucosal immune responses in the initiation or perpetuation of the systemic autoimmunity that occurs wi

207 nerated a lung cytokine profile conducive to perpetuation of the Th1 memory population.

208 re often identified as key components in the perpetuation of these phenomena.

209 ical role of the innate immune system in the perpetuation of this autoimmune disease.

210 une mechanisms underlying the initiation and perpetuation of this condition.

211 is homochiral and effective enforcement and perpetuation of this homochirality is essential for cell

212 The mechanisms of lethality and the perpetuation of this lethal phenotype in ducks in nature

213 acids may play a role in the initiation and perpetuation of this sensitized state.

214 The perpetuation of this system requires that reproductives

215 Perpetuation of tumor-induced osteolysis requires a cont

216 protein was believed to be essential for the perpetuation of two Apicomplexa parasite genera, Plasmod

217 recently been associated with initiation and perpetuation of various neurological disorders, an intac

218 ites that participated in the initiation and perpetuation of various tachyarrhythmias.

219 Excessive expansive remodeling leads to perpetuation, or even exacerbation, of the local low end

220 ssue inhibitor of matrix metalloproteinases (perpetuation phase of stellate cell activation) were als

221 This form of perpetuation, previously unseen in any organism, arises

222 Ca2+ -handling remodeling contribute to the perpetuation/progression of atrial fibrillation (AF).

223 data point to a genomic mechanism for repeat perpetuation rather than a positive cellular role.

224 depends on the balance of factors that favor perpetuation versus resolution.

225 ed to identify the factors involved in viral perpetuation within natural host populations, and driver