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1 quences were displayed on the HOC protein of phage T4.
2 vI, the other homing endonuclease encoded by phage T4.
3 hat have been invoked for intron mobility in phage T4.
4 and bacteriophages, including the dCTPase of phage T4.
5 cific regions of extensive conservation with phage T4.
6  in vitro and in vivo, compared with that of phage T4.
7 omain--a second RNA ligase (Rnl2) encoded by phage T4.
8  homologous TS gene (td) of Escherichia coli phage T4.
9 of single DNA molecule packaging dynamics in phage T4, a large, tailed Escherichia coli virus that is
10 he ghmC modification cannot abolish the anti-phage T4 activities of Septu, SspBCDE, and mzaABCDE, alt
11                                     The anti-phage T4 activities of the last two systems can also be
12 and Bacillus subtilis, we discover Acb1 from phage T4 and Apyc1 from phage SBSphiJ as founding member
13                         Here, by focusing on phage T4 and its host Escherichia coli, we depicted the
14                         Here, by focusing on phage T4 and its host Escherichia coli, we depicted the
15  a pattern similar to what has been noted in phage T4 and its relatives, in which there is minimal su
16                          In Escherichia coli phage T4 and many of its phylogenetic relatives, gene 43
17 common lytic tracer phages (Escherichia coli phage T4 and marine phage PSA-HS2) and two mycelia of di
18 teria, introns have been encountered only in phage T4 and several of its close relatives.
19 ich includes the introns in Escherichia coli phage T4 and the Bacillus phages beta22 and SPO1.
20 e with those found in the gene 61 primase of phage T4 and the DnaG primase of Escherichia coli.
21 ination factor Rho, that block the growth of phages T4 and lambdar32.
22 e DNA polymerases (gp43s) of the two related phages T4 and RB69 are DNA-binding proteins that also fu
23 coded helicases, including UvsW and D10 from phages T4 and T5.
24 ent (KF) and two other DNA polymerases, from phages T4 and T7.
25 ral recombination is essential for growth of phage T4, because origin initiation of DNA replication i
26 uous packaged DNA structures are favored for phage T4 by a number of lines of evidence.
27                         The data showed that phage T4 can successfully package and transduce 4 to 29
28                                  Unlike most phages, T4 can sense superinfection (which signals the d
29                                          The phage T4 capsid lattice provides a stable biological pla
30  and an engineered gp41 C-peptide trimer, on phage T4 capsid surface through Hoc-capsid interactions.
31 anthrax toxin molecules are assembled on the phage T4 capsid under controlled conditions.
32  6-adenine]-methyltransferase (Dam MTase) of phage T4 catalyzes methyl group transfer from S-adenosyl
33 striction-like system specifically restricts phage T4 containing an hmC-modified genome.
34 sed on the crystallographic structure of its phage T4 counterpart.
35 ly revealed its sequence relationship to the phage T4 dCTPase, phosphoribosyl-ATP pyrophosphatase His
36                                           In phage T4 development the gene 59 protein (gp59) assemble
37                                       Mature phage T4 DNA and linearized plasmid DNAs containing or l
38 ides were used as templates for synthesis by phage T4 DNA polymerase holoenzyme proficient or deficie
39 uble-stranded DNA unwinding catalyzed by the phage T4 DNA replication helicase (gp41).
40 cesses occurring during the formation of the phage T4 DNA sliding clamp, we have performed direct sub
41                                              Phage T4 effects lysis by its holin T and its endolysin
42                       We have identified the phage T4-encoded sigma factor gp55 and the co-activator
43                                              Phage T4 endonuclease VII (endo VII) was the first enzym
44   Like most phages with double-stranded DNA, phage T4 exits the infected host cell by a lytic process
45  protein, sCARfC6.5, that consisted of sCAR, phage T4 fibritin polypeptide, and C6.5 single-chain fra
46  construct by fusing a foldon domain (FD) of phage T4 fibritin to the MA C terminus.
47 different proteins: the Ad serotype 5 fiber, phage T4 fibritin, and the human CD40 ligand (CD40L).
48                                              Phage T4 gene 32 protein (gp32) is a zinc metalloprotein
49 ammed ribosomal bypassing occurs in decoding phage T4 gene 60 mRNA.
50  Half the ribosomes translating the mRNA for phage T4 gene 60 topoisomerase subunit bypass a 50 nucle
51 ncoded by Escherichia coli (SSB protein) and phage T4 (gene 32 protein) also have acidic COOH-termina
52 progeny of mixed infections with the related phage T4 (general, or phage exclusion).
53                            We found that the phage T4 genome modified by cytosine hydroxymethylation
54  terminases and bear great similarity to the phage T4 gp17 but are distinct from podovirus and siphov
55 e report single-molecule measurements of the phage T4 gp17 motor by using dual-trap optical tweezers
56                                          The phage T4 gp45 sliding clamp is a ring-shaped replication
57 nisms such as Escherichia coli, phage T7 and phage T4 has demonstrated the essential nature of primas
58                                  The tail of phage T4 has long served as the paradigm for understandi
59                                              Phage T4 has many optional homing endonuclease genes sim
60                                              Phage T4 has three group I introns, within the td, nrdB
61               Escherichia coli and selective phages T4 have been used as case study.
62                Here, the catalytic centre of phage T4 headful nuclease, present in the C-terminal dom
63  of the interaction was tested by means of a phage T4 HOC (highly antigenicoutercapsid protein) displ
64                    The data suggest that the phage T4 hoc-soc system is an attractive system for disp
65 the complex roles of genomic modification of phage T4 in countering these defense systems.
66                                        A new phage T4 in vitro DNA packaging assay employed purified
67 The end-healing and end-sealing steps of the phage T4-induced RNA restriction-repair pathway are perf
68             A ribosome profiling analysis of phage T4-infected Escherichia coli yielded protected mRN
69 ning systems were found to be active against phage T4 infection.
70 (EcoPrrC) underlies an antiviral response to phage T4 infection.
71 ccumulate in prohead and terminase defective phage T4 infections could be packaged in vitro to approx
72 del describing the nonlinear dynamics of the phage T4 injection machinery interacting with a host cel
73     The DNA-binding DNA polymerase (gp43) of phage T4 is also an RNA-binding protein that represses t
74 richia coli Although the atomic structure of phage T4 is largely understood, the dynamics of its inje
75 ve bacteria and AQUIFEX: Endonuclease VII of phage T4 is shown to serve as a structural template for
76 and "join-cut-copy," can be distinguished in phage T4: join-copy requires only early and middle genes
77 gnition and ATP hydrolysis in the pentameric phage T4 large "terminase" (gp17) motor.
78          We have probed the mechanism of the phage T4 large terminase subunit gp17 by analyzing linea
79                               gp55-dependent phage T4 late promoter transcription is also resistant t
80 lease HI (RNase H) from Escherichia coli and phage T4 lysozyme (T4L) both exhibit such a phenomenon.
81 lease HI from Escherichia coli (RNase H) and phage T4 lysozyme (T4L) reveal that, for both proteins,
82                             The complexes of phage T4 lysozyme L99A with noble gases have been studie
83  solution with a number of cavity containing phage T4 lysozyme mutants show that xenon can report on
84 ned 434 cro variants, as well as a series of phage T4 lysozyme variants.
85 e A2, proteinase A, rubredoxin, thrombin and phage T4 lysozyme) and appear with similar coordination
86                  This strategy was tested on phage T4 lysozyme, a protein whose crystallization as a
87  and another that is structurally similar to phage T4 lysozyme.
88 gram ORBIT, was used to redesign the core of phage T4 lysozyme.
89 seudo wild-type and cavity-containing mutant phage T4 lysozymes in the presence of argon, krypton, an
90              The availability of a series of phage T4 lysozymes with up to 14 methionine residues inc
91 modulated by substrate DNA sequence: (i) the phage T4 motor exhibits large translocation rate fluctua
92                                          The phage T4 motor is composed of a dodecameric portal and s
93                                          The phage T4 motor is composed of the small terminase protei
94                                          The phage T4 motor is constituted by gene product 16 (gp16)
95 sity twice that of an automobile engine, the phage T4 motor is the fastest and most powerful reported
96                                          The phage T4 motor, a pentamer of 70-kDa large terminase, gp
97 he new approach is based on using label-free phages (T4), obligate parasites of bacteria, which are a
98                             Intron homing in phage T4 occurs in the context of recombination-dependen
99 ely 2,000 bp/s, consistent with packaging by phage T4 of an enormous, 171-kb genome in <10 min during
100               These results suggest that the phage T4 packaging machine consists of a motor (gp17) an
101                                          The phage T4 packaging machine consists of three components:
102 id packaging results show that initiation of phage T4 packaging on "endless" concatemeric DNA in vivo
103 g experiments, we observed that the in vitro phage T4 packaging system can package and transduce DNA
104                                    A defined phage T4 packaging system consisting of only two compone
105                                  A bipartite phage T4 peptide library was created by displaying on te
106                     DNA polymerase (gp43) of phage T4 plays two biological roles, one as an essential
107                       Structural analysis of phage T4 portal (gp20) has been hampered because of its
108                                              Phage T4 protects its DNA from the two-gene-encoded gmrS
109 s (equivalent to the 11 residues of 43P from phage T4) protrude from the thumb domain and are free to
110 e two-dimensional gel analysis also revealed phage T4 replication intermediates not previously detect
111 ication structures generated by the in vitro phage T4 replication system were analyzed using two-dime
112 ted sliding-clamp processivity factor of the phage T4 replisome (gp45, the activator).
113                               Loading of the phage T4 sliding clamp gp45 by the gp44/62 clamp loader
114         First, optimization experiments with phage T4 spiked in complex matrices (without a phage amp
115 , the ribosome bypass (or "hop") sequence of phage T4 stands out as a uniquely extreme example of pro
116                                          The phage T4 system offers new direction and insights for HI
117                            DNA polymerase of phage T4 (T4 gp43), an essential component of the T4 DNA
118 ome were inserted upstream of a promoterless phage T4 td gene, and fragments that led to complementat
119  contrasts with efficient inheritance of the phage T4 td group I intron and its endonuclease, I-TevI,
120                                          The phage T4 td intron endonuclease, I-TevI, is responsible
121                                Homing of the phage T4 td intron is initiated by the intron-encoded en
122  Escherichia coli genetic assay based on the phage T4 td intron to systematically test the ability of
123  Escherichia coli genetic assay based on the phage T4 td intron to test the ability of the Neurospora
124                                  I-TevI, the phage T4 td intron-encoded endonuclease, recognizes a le
125 ent and stabilization of functional sites in phage T4 terminase and other double-stranded DNA phage t
126 ET has shown a decrease in distance from the phage T4 terminase C terminus to portal consistent with
127                             Mutations in the phage T4 terminase C-motif lead to loss of stimulated AT
128                                              Phage T4 terminase is a two-subunit enzyme that binds to
129                                              Phage T4 terminase is an enzyme that binds to the portal
130  bipartite library was biopanned against the phage T4 terminase large subunit gp17 to identify T4 gen
131                      We have constructed new phage T4 terminase recombinants under the control of pha
132  packaged into empty viral procapsids by the phage T4 terminase with high efficiency in vitro.
133 t that mutations of basic residues that line phage T4 TerS (gp16) channel do not disrupt DNA binding.
134 G family endonuclease adjacent to gene 32 of phage T4 that is absent from phage T2.
135                                          For phage T4, the most obvious change is the contraction of
136                                           In phage T4, the pseudoknot is contained within 28 contiguo
137                                           In phage T4, there is evidence that the large terminase pro
138                                           In phage T4, there is evidence that this vertex, constitute
139                                           In phage T4 they are genes 16 and 17.
140                                           In phage T4 this complex consists of a trimeric clamp of gp
141 g capabilities that were observed, may allow phage T4 to coordinate DNA packaging with other ongoing
142 vsY, 46 and 59) increased the sensitivity of phage T4 to m-AMSA, strongly suggesting that recombinati
143 nal bypassing of a 50-nt non-coding gap in a phage T4 topoisomerase subunit gene (gp60) requires seve
144 f RNase BN is not required for maturation of phage T4 tRNA precursors, a known specific function of t
145                                              Phage T4, unlike the phages with defined ends (e.g. lamb
146                                          The phage T4 UvsW protein has been shown to play a crucial r
147 hat targets the thymidylate synthase gene of phage T4, we readily isolated variants that dramatically
148 x-site terminated plasmid DNAs injected from phage T4 were recircularized by T4 ligase in vivo with a

 
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